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Illumina Body Map 2: averaged replicates

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Results for HOXA1

Z-value: 1.86

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
ENSG00000105991.7 HOXA1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA1hg19_v2_chr7_-_27135591_271356580.421.6e-02Click!

Activity profile of HOXA1 motif

Sorted Z-values of HOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_10697895 9.17 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr2_-_154335300 4.12 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_-_91095099 3.46 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_+_107682629 3.37 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr8_-_27115903 3.03 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr19_-_51192661 3.02 ENST00000391813.1
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr8_+_104152922 2.99 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC
brain and acute leukemia, cytoplasmic
chr6_+_80129989 2.91 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr12_-_95510743 2.63 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr22_+_29834572 2.59 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr17_+_40932610 2.53 ENST00000246914.5
WNK4
WNK lysine deficient protein kinase 4
chr18_-_3874271 2.48 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_65730385 2.39 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_104153126 2.38 ENST00000306391.6
ENST00000330955.5
BAALC
brain and acute leukemia, cytoplasmic
chr8_-_27115931 2.36 ENST00000523048.1
STMN4
stathmin-like 4
chr11_-_93583697 2.34 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr22_+_41968007 2.29 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr17_-_38821373 2.19 ENST00000394052.3
KRT222
keratin 222
chrX_+_134654540 2.19 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_-_22549856 2.18 ENST00000522910.1
EGR3
early growth response 3
chr1_+_240255166 2.11 ENST00000319653.9
FMN2
formin 2
chrX_-_154493791 2.05 ENST00000369454.3
RAB39B
RAB39B, member RAS oncogene family
chrX_-_13835147 2.05 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr18_-_70305745 2.03 ENST00000581073.1
CBLN2
cerebellin 2 precursor
chr2_+_149632783 2.02 ENST00000435030.1
KIF5C
kinesin family member 5C
chr4_+_113970772 1.98 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr15_-_63674034 1.95 ENST00000344366.3
ENST00000422263.2
CA12
carbonic anhydrase XII
chr3_-_161090660 1.90 ENST00000359175.4
SPTSSB
serine palmitoyltransferase, small subunit B
chr20_+_58203664 1.85 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr8_+_143530791 1.83 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr19_-_38746979 1.82 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr2_-_112237835 1.81 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr14_-_106692191 1.78 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr12_-_85306594 1.76 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr1_-_241520385 1.76 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr3_+_125985620 1.76 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr17_-_42988004 1.73 ENST00000586125.1
ENST00000591880.1
GFAP
glial fibrillary acidic protein
chr2_+_24272576 1.72 ENST00000380986.4
ENST00000452109.1
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr15_-_63674218 1.71 ENST00000178638.3
CA12
carbonic anhydrase XII
chr2_-_50574856 1.70 ENST00000342183.5
NRXN1
neurexin 1
chr7_+_20370746 1.59 ENST00000222573.4
ITGB8
integrin, beta 8
chr1_+_107683436 1.59 ENST00000370068.1
NTNG1
netrin G1
chr11_+_63870660 1.58 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr1_-_203198790 1.56 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr14_-_106725723 1.54 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr9_+_132962843 1.52 ENST00000458469.1
NCS1
neuronal calcium sensor 1
chr11_-_88796803 1.49 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr16_+_23847339 1.45 ENST00000303531.7
PRKCB
protein kinase C, beta
chr8_-_22550691 1.44 ENST00000519492.1
EGR3
early growth response 3
chr1_+_2005425 1.42 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr2_-_175711978 1.39 ENST00000409089.2
CHN1
chimerin 1
chr14_+_91709103 1.39 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr17_-_79359154 1.38 ENST00000572077.1
RP11-1055B8.3
RP11-1055B8.3
chr22_-_30642728 1.36 ENST00000403987.3
LIF
leukemia inhibitory factor
chr7_-_100808394 1.35 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr7_-_994302 1.35 ENST00000265846.5
ADAP1
ArfGAP with dual PH domains 1
chr17_+_26800296 1.32 ENST00000444914.3
ENST00000314669.5
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr3_-_150264272 1.32 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr1_+_26872324 1.32 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_+_39975544 1.30 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr12_+_48577366 1.29 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr9_+_33795533 1.29 ENST00000379405.3
PRSS3
protease, serine, 3
chr16_+_25703274 1.27 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr12_-_85306562 1.26 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr12_-_52911718 1.26 ENST00000548409.1
KRT5
keratin 5
chr6_+_121756809 1.26 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_154178520 1.26 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr5_+_159656437 1.26 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr10_+_18689637 1.26 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_+_68071389 1.24 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr9_-_101471479 1.23 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr17_-_42276574 1.19 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr22_+_25615489 1.19 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr17_+_39975455 1.17 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr7_-_100808843 1.17 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr11_-_126870655 1.15 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr1_+_85527987 1.14 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WDR63
WD repeat domain 63
chr2_+_24272543 1.14 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr17_-_79359046 1.12 ENST00000574041.1
RP11-1055B8.3
RP11-1055B8.3
chr7_-_137028498 1.10 ENST00000393083.2
PTN
pleiotrophin
chr20_+_34742650 1.09 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr7_-_137028534 1.08 ENST00000348225.2
PTN
pleiotrophin
chr5_-_125930877 1.07 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr7_+_30174574 1.06 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr14_-_23822061 1.06 ENST00000397260.3
SLC22A17
solute carrier family 22, member 17
chr22_-_22641542 1.05 ENST00000606654.1
LL22NC03-2H8.5
LL22NC03-2H8.5
chr20_-_30458491 1.04 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr9_+_87285257 1.03 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr15_-_64673630 1.03 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr17_-_79359021 1.03 ENST00000572301.1
RP11-1055B8.3
RP11-1055B8.3
chr7_+_79765071 1.02 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_+_151561085 1.02 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr18_-_3874247 1.02 ENST00000581699.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr6_-_154677900 1.02 ENST00000265198.4
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr22_+_42394780 1.02 ENST00000328823.9
WBP2NL
WBP2 N-terminal like
chrX_-_63005405 1.02 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr20_+_36012051 1.02 ENST00000373567.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr8_-_79717750 1.01 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr17_-_42277203 1.01 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr6_-_154677866 1.00 ENST00000367220.4
IPCEF1
interaction protein for cytohesin exchange factors 1
chr11_-_40314652 1.00 ENST00000527150.1
LRRC4C
leucine rich repeat containing 4C
chr13_-_23490508 1.00 ENST00000577004.1
LINC00621
long intergenic non-protein coding RNA 621
chr12_-_55378452 0.99 ENST00000449076.1
TESPA1
thymocyte expressed, positive selection associated 1
chr9_-_10612703 0.99 ENST00000463477.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr5_-_173173171 0.98 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
CTB-43E15.3
chr5_-_125930929 0.98 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr5_+_177433406 0.96 ENST00000504530.1
FAM153C
family with sequence similarity 153, member C
chr6_+_151561506 0.96 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr15_-_74501310 0.96 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr16_+_23847267 0.95 ENST00000321728.7
PRKCB
protein kinase C, beta
chr7_+_30174668 0.95 ENST00000415604.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr9_-_123676827 0.95 ENST00000546084.1
TRAF1
TNF receptor-associated factor 1
chr6_-_36725157 0.93 ENST00000393189.2
CPNE5
copine V
chr14_+_102196739 0.93 ENST00000556973.1
RP11-796G6.2
Uncharacterized protein
chr12_-_101604185 0.92 ENST00000536262.2
SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr11_-_40315640 0.91 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr8_-_27468842 0.90 ENST00000523500.1
CLU
clusterin
chr6_+_99282570 0.90 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chrX_-_10645773 0.89 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr5_-_693500 0.89 ENST00000360578.5
TPPP
tubulin polymerization promoting protein
chr19_-_49944806 0.88 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr2_+_121493717 0.88 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr3_+_4535155 0.88 ENST00000544951.1
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr11_+_105480793 0.87 ENST00000282499.5
ENST00000393127.2
ENST00000527669.1
GRIA4
glutamate receptor, ionotropic, AMPA 4
chrX_+_82763265 0.87 ENST00000373200.2
POU3F4
POU class 3 homeobox 4
chr17_-_79358929 0.85 ENST00000570301.1
RP11-1055B8.3
RP11-1055B8.3
chr19_+_5681011 0.85 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr17_-_40835076 0.85 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr7_-_115670792 0.85 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr11_-_126870683 0.84 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr14_-_106406090 0.84 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr3_+_44916098 0.84 ENST00000296125.4
TGM4
transglutaminase 4
chr1_+_86889769 0.83 ENST00000370565.4
CLCA2
chloride channel accessory 2
chr10_-_28270795 0.83 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr20_+_8112824 0.83 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr14_-_101053739 0.83 ENST00000554140.1
BEGAIN
brain-enriched guanylate kinase-associated
chr16_+_23847355 0.82 ENST00000498058.1
PRKCB
protein kinase C, beta
chr6_+_31021225 0.82 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr15_+_101402041 0.82 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr15_+_48009541 0.81 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr10_-_98945677 0.81 ENST00000266058.4
ENST00000371041.3
SLIT1
slit homolog 1 (Drosophila)
chr12_-_129570545 0.81 ENST00000389441.4
TMEM132D
transmembrane protein 132D
chr7_-_22233442 0.81 ENST00000401957.2
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_162601774 0.81 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr3_-_149688655 0.81 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2
profilin 2
chr3_+_4535025 0.80 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr8_-_27469196 0.80 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr6_+_31021973 0.80 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HCG22
HLA complex group 22
chr3_+_38537960 0.80 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr4_+_166300084 0.80 ENST00000402744.4
CPE
carboxypeptidase E
chr2_+_166326157 0.80 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr8_-_27468945 0.80 ENST00000405140.3
CLU
clusterin
chr11_+_105480740 0.79 ENST00000393125.2
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr11_+_133902667 0.79 ENST00000533091.1
ENST00000527712.1
RP11-713P17.3
RP11-713P17.3
chr12_+_57998400 0.78 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr5_+_36152091 0.78 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr17_-_72619783 0.77 ENST00000328630.3
CD300E
CD300e molecule
chr7_-_115670804 0.76 ENST00000320239.7
TFEC
transcription factor EC
chr19_-_51141196 0.75 ENST00000338916.4
SYT3
synaptotagmin III
chrX_+_128913906 0.75 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr7_+_141418962 0.74 ENST00000493845.1
WEE2
WEE1 homolog 2 (S. pombe)
chr8_+_86099884 0.74 ENST00000517476.1
ENST00000521429.1
E2F5
E2F transcription factor 5, p130-binding
chr3_+_98250743 0.74 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr4_+_86396265 0.74 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr16_+_57680840 0.74 ENST00000563862.1
ENST00000564722.1
ENST00000569158.1
GPR56
G protein-coupled receptor 56
chr15_-_74501360 0.73 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr2_-_190044480 0.71 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chrX_-_10645724 0.71 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr3_-_145878954 0.70 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr6_-_28973037 0.70 ENST00000377179.3
ZNF311
zinc finger protein 311
chr16_+_57680811 0.69 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr1_+_202976493 0.69 ENST00000367242.3
TMEM183A
transmembrane protein 183A
chr9_-_116861337 0.69 ENST00000374118.3
KIF12
kinesin family member 12
chr15_-_64673665 0.69 ENST00000300035.4
KIAA0101
KIAA0101
chr8_-_114449112 0.68 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr1_-_205819245 0.66 ENST00000367136.4
PM20D1
peptidase M20 domain containing 1
chr13_+_92050928 0.66 ENST00000377067.3
GPC5
glypican 5
chrX_-_148586804 0.66 ENST00000428056.2
ENST00000340855.6
ENST00000370441.4
ENST00000370443.4
IDS
iduronate 2-sulfatase
chr17_-_8027402 0.65 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr4_+_166128836 0.64 ENST00000511305.1
KLHL2
kelch-like family member 2
chr17_-_27278445 0.64 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr14_-_77965151 0.63 ENST00000393684.3
ENST00000493585.1
ENST00000554801.2
ENST00000342219.4
ENST00000412904.1
ENST00000429906.1
ISM2
isthmin 2
chr3_-_56950407 0.63 ENST00000496106.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr19_-_40732594 0.62 ENST00000430325.2
ENST00000433940.1
CNTD2
cyclin N-terminal domain containing 2
chr4_+_2451700 0.62 ENST00000506607.1
RP11-503N18.3
Uncharacterized protein
chr20_+_30467600 0.62 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr1_+_116915270 0.60 ENST00000418797.1
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr10_+_106937525 0.60 ENST00000369699.4
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr11_-_5248294 0.60 ENST00000335295.4
HBB
hemoglobin, beta
chr11_+_61717279 0.59 ENST00000378043.4
BEST1
bestrophin 1
chr11_-_72353451 0.59 ENST00000376450.3
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr7_+_142448053 0.58 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr11_-_84844167 0.57 ENST00000527088.1
DLG2
discs, large homolog 2 (Drosophila)
chr12_+_78359999 0.57 ENST00000550503.1
NAV3
neuron navigator 3
chr14_+_24702127 0.57 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr11_-_2193025 0.56 ENST00000333684.5
ENST00000381178.1
ENST00000381175.1
ENST00000352909.3
TH
tyrosine hydroxylase
chr8_-_27468717 0.56 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr11_+_122753391 0.56 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr11_+_61717336 0.56 ENST00000378042.3
BEST1
bestrophin 1
chrX_+_37639302 0.56 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0050894 determination of affect(GO:0050894)
0.8 3.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.7 2.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.7 2.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.7 2.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.6 2.5 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.6 1.8 GO:0035038 female pronucleus assembly(GO:0035038)
0.5 2.0 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.5 3.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 1.7 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.4 3.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.4 2.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.4 3.5 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.4 2.6 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.4 3.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.3 1.3 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.3 3.0 GO:0015820 leucine transport(GO:0015820)
0.3 0.9 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.3 0.9 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.3 1.7 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.7 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 0.8 GO:0090427 activation of meiosis(GO:0090427)
0.3 1.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 1.0 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.2 1.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 3.4 GO:0010459 negative regulation of heart rate(GO:0010459)
0.2 1.9 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.2 2.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2 0.8 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.2 1.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 1.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2 0.6 GO:0042214 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.2 2.0 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.2 0.7 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.5 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.2 1.0 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.2 1.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 0.5 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.2 0.7 GO:0043605 cellular amide catabolic process(GO:0043605)
0.2 1.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 0.8 GO:0030070 insulin processing(GO:0030070)
0.2 1.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 0.5 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.2 0.5 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.2 1.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.6 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.5 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 1.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.9 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 9.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 1.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.1 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 7.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 1.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 2.0 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.9 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 2.3 GO:0002021 response to dietary excess(GO:0002021)
0.1 3.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.0 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.8 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 1.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 5.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.9 GO:2001054 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.1 0.6 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 1.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:2000589 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 2.9 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.5 GO:0016578 histone deubiquitination(GO:0016578)
0.0 1.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 1.9 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 1.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.6 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.3 GO:2000111 positive regulation of macrophage apoptotic process(GO:2000111)
0.0 4.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 1.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 5.6 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 1.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 1.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0060178 regulation of exocyst assembly(GO:0001928) regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 1.9 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.4 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.2 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.9 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.4 GO:0006833 water transport(GO:0006833)
0.0 0.6 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0072678 T cell migration(GO:0072678)
0.0 1.2 GO:0045087 innate immune response(GO:0045087)
0.0 1.5 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.5 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0009595 detection of biotic stimulus(GO:0009595)
0.0 1.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.3 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 1.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 1.0 GO:0033011 perinuclear theca(GO:0033011)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.2 0.9 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 1.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 9.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.5 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 2.0 GO:0035253 ciliary rootlet(GO:0035253)
0.1 3.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 2.1 GO:0000124 SAGA complex(GO:0000124)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 4.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.4 GO:0045179 apical cortex(GO:0045179)
0.1 4.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.9 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916)
0.1 0.5 GO:0033263 CORVET complex(GO:0033263)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 2.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 5.9 GO:0043195 terminal bouton(GO:0043195)
0.0 3.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 17.7 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 2.9 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.7 GO:0097546 ciliary base(GO:0097546)
0.0 2.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.5 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 3.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 4.0 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 2.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0030054 cell junction(GO:0030054)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 0.6 GO:0030286 dynein complex(GO:0030286)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
1.0 3.0 GO:0031877 somatostatin receptor binding(GO:0031877)
0.8 3.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.6 2.9 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.5 2.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.5 1.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.4 1.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.4 1.7 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.6 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.2 1.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.7 GO:0004423 iduronate-2-sulfatase activity(GO:0004423)
0.2 0.8 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 3.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.2 2.9 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 2.3 GO:0071253 connexin binding(GO:0071253)
0.2 0.7 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.0 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 0.5 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 0.5 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.2 0.5 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 1.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.5 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 1.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.6 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.3 GO:0032052 bile acid binding(GO:0032052)
0.1 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.4 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 4.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.9 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 2.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 1.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 1.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.1 1.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.1 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.9 GO:0035173 histone kinase activity(GO:0035173)
0.0 1.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 2.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.6 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 3.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0020037 heme binding(GO:0020037)
0.0 1.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 4.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.4 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0001632 leukotriene B4 receptor activity(GO:0001632)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 3.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 5.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 4.2 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.2 PID MYC PATHWAY C-MYC pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID SHP2 PATHWAY SHP2 signaling
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 3.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 6.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 2.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.4 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.7 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.6 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.1 2.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.0 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases