Motif ID: HOXA2_HOXB1

Z-value: 2.194

Transcription factors associated with HOXA2_HOXB1:

Gene SymbolEntrez IDGene Name
HOXA2 ENSG00000105996.5 HOXA2
HOXB1 ENSG00000120094.6 HOXB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXB1hg19_v2_chr17_-_46608272_466083850.251.6e-01Click!
HOXA2hg19_v2_chr7_-_27142290_271424300.077.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_93616340 14.318 ENST00000557420.1
ENST00000542321.2
RGMA

repulsive guidance molecule family member a

chr12_+_101988627 14.011 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr12_+_101988774 13.316 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1





myosin binding protein C, slow type





chr15_-_93616892 10.409 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA


repulsive guidance molecule family member a


chr16_-_49890016 8.374 ENST00000563137.2
ZNF423
zinc finger protein 423
chr17_-_37353950 7.284 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr6_+_151561085 6.423 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_154335300 6.057 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr11_-_111782696 5.649 ENST00000227251.3
ENST00000526180.1
CRYAB

crystallin, alpha B

chr6_+_151561506 5.636 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_111782484 5.389 ENST00000533971.1
CRYAB
crystallin, alpha B
chr12_-_15038779 4.987 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr18_+_56887381 4.551 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
GRP


gastrin-releasing peptide


chr20_+_34802295 4.250 ENST00000432603.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr17_+_37824411 4.248 ENST00000269582.2
PNMT
phenylethanolamine N-methyltransferase
chr16_-_79263322 4.139 ENST00000569677.1
RP11-679B19.2
RP11-679B19.2
chr7_-_27170352 3.941 ENST00000428284.2
ENST00000360046.5
HOXA4

homeobox A4

chr17_+_37824217 3.938 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr5_+_98109322 3.918 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr11_-_2162162 3.900 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_189507523 3.660 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63




tumor protein p63




chr17_+_39975544 3.651 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr16_+_7560114 3.606 ENST00000570626.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_39975455 3.588 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr3_-_187388173 3.493 ENST00000287641.3
SST
somatostatin
chr17_+_37824700 3.492 ENST00000581428.1
PNMT
phenylethanolamine N-methyltransferase
chrX_-_13835398 3.328 ENST00000475307.1
GPM6B
glycoprotein M6B
chr14_-_54425475 3.324 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chrX_-_13835147 2.991 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr16_+_15596123 2.979 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr19_-_49944806 2.969 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chrX_-_13835461 2.936 ENST00000316715.4
ENST00000356942.5
GPM6B

glycoprotein M6B

chr2_-_45236540 2.793 ENST00000303077.6
SIX2
SIX homeobox 2
chr16_+_66429358 2.784 ENST00000539168.1
CDH5
cadherin 5, type 2 (vascular endothelium)
chr3_+_189507432 2.772 ENST00000354600.5
TP63
tumor protein p63
chr10_+_24755416 2.711 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr5_-_125930877 2.703 ENST00000510111.2
ENST00000509270.1
ALDH7A1

aldehyde dehydrogenase 7 family, member A1

chr11_-_126870683 2.641 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr2_+_176995011 2.635 ENST00000548663.1
ENST00000450510.2
HOXD8

homeobox D8

chr6_-_112575687 2.603 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr14_-_21516590 2.498 ENST00000555026.1
NDRG2
NDRG family member 2
chr6_-_112575912 2.362 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr2_+_36923901 2.315 ENST00000457137.2
VIT
vitrin
chrX_-_10645773 2.292 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr7_-_86595190 2.265 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L


KIAA1324-like


chr3_+_112929850 2.258 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr3_+_159481988 2.245 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr6_+_155334780 2.209 ENST00000538270.1
ENST00000535231.1
TIAM2

T-cell lymphoma invasion and metastasis 2

chr4_-_5021164 2.188 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
CYTL1


cytokine-like 1


chr7_-_25790603 2.160 ENST00000456777.1
AC003090.1
AC003090.1
chrX_+_99899180 2.159 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr10_-_100995540 2.146 ENST00000370546.1
ENST00000404542.1
HPSE2

heparanase 2

chr6_-_112575758 2.130 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4



laminin, alpha 4



chr5_-_125930929 2.117 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr10_-_79397202 1.980 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1


potassium large conductance calcium-activated channel, subfamily M, alpha member 1


chr16_+_25703274 1.977 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr12_-_28124903 1.890 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr2_-_23747214 1.880 ENST00000430988.1
AC011239.1
Uncharacterized protein
chr2_+_36923933 1.863 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
VIT



vitrin



chr20_+_34742650 1.863 ENST00000373945.1
ENST00000338074.2
EPB41L1

erythrocyte membrane protein band 4.1-like 1

chr21_+_19617140 1.857 ENST00000299295.2
ENST00000338326.3
CHODL

chondrolectin

chr10_-_79397316 1.834 ENST00000372421.5
ENST00000457953.1
KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

chr3_+_148545586 1.798 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr10_-_105615164 1.798 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chr2_+_36923830 1.764 ENST00000379242.3
ENST00000389975.3
VIT

vitrin

chr11_-_93583697 1.719 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr10_+_95848824 1.718 ENST00000371385.3
ENST00000371375.1
PLCE1

phospholipase C, epsilon 1

chr7_+_79765071 1.634 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr13_-_36050819 1.609 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr10_+_124320156 1.608 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chr3_-_46786245 1.551 ENST00000442359.2
PRSS45
protease, serine, 45
chr10_-_100995603 1.530 ENST00000370552.3
ENST00000370549.1
HPSE2

heparanase 2

chr20_+_52105495 1.501 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr7_-_150864635 1.495 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr10_-_79397547 1.476 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_+_48609903 1.418 ENST00000268933.3
EPN3
epsin 3
chr7_+_26591441 1.416 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2


AC004947.2


chr12_-_49393092 1.402 ENST00000421952.2
DDN
dendrin
chr17_+_36584662 1.401 ENST00000431231.2
ENST00000437668.3
ARHGAP23

Rho GTPase activating protein 23

chr9_+_124329336 1.380 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr7_+_20370746 1.357 ENST00000222573.4
ITGB8
integrin, beta 8
chr10_-_79397479 1.265 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_113431029 1.252 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_+_189507460 1.243 ENST00000434928.1
TP63
tumor protein p63
chr7_+_86273218 1.229 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr10_-_98945264 1.227 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr7_-_14029515 1.216 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1


ets variant 1


chr6_+_73331520 1.215 ENST00000342056.2
ENST00000355194.4
KCNQ5

potassium voltage-gated channel, KQT-like subfamily, member 5

chr15_-_74501310 1.210 ENST00000423167.2
ENST00000432245.2
STRA6

stimulated by retinoic acid 6

chr16_-_67427389 1.199 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3


tubulin polymerization-promoting protein family member 3


chr1_-_217250231 1.143 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr1_+_178062855 1.116 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr8_-_38008783 1.112 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr6_-_112575838 1.107 ENST00000455073.1
LAMA4
laminin, alpha 4
chr11_-_126870655 1.100 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr3_+_150264555 1.077 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A


eukaryotic translation initiation factor 2A, 65kDa


chr10_+_18689637 1.072 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr17_-_57604200 1.071 ENST00000577478.1
RP11-567L7.6
RP11-567L7.6
chr8_+_143530791 1.062 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr15_+_48009541 1.046 ENST00000536845.2
ENST00000558816.1
SEMA6D

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr2_+_46706725 1.039 ENST00000434431.1
TMEM247
transmembrane protein 247
chr10_+_124320195 0.990 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr12_-_114843889 0.989 ENST00000405440.2
TBX5
T-box 5
chr3_+_150264458 0.985 ENST00000487799.1
ENST00000460851.1
EIF2A

eukaryotic translation initiation factor 2A, 65kDa

chr12_+_7023491 0.977 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chrX_+_125953746 0.936 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr1_-_67390474 0.924 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78



WD repeat domain 78



chrX_-_10645724 0.911 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr7_-_120497178 0.905 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr1_-_182642017 0.902 ENST00000367557.4
ENST00000258302.4
RGS8

regulator of G-protein signaling 8

chr3_+_239652 0.856 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chr4_-_90757364 0.825 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr8_-_67874805 0.824 ENST00000563496.1
TCF24
transcription factor 24
chr2_-_190044480 0.801 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr9_-_101471479 0.776 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr11_+_133902667 0.770 ENST00000533091.1
ENST00000527712.1
RP11-713P17.3

RP11-713P17.3

chr9_+_113431059 0.767 ENST00000416899.2
MUSK
muscle, skeletal, receptor tyrosine kinase
chr1_-_205391178 0.752 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1



LEM domain containing 1



chr2_+_26624775 0.751 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr2_-_142888573 0.748 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chrX_+_82763265 0.747 ENST00000373200.2
POU3F4
POU class 3 homeobox 4
chr18_+_18943554 0.740 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr6_+_29426230 0.732 ENST00000442615.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chr6_+_32006042 0.715 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_242089833 0.715 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7



protein phosphatase 1, regulatory subunit 7



chr4_-_113437328 0.654 ENST00000313341.3
NEUROG2
neurogenin 2
chr4_-_90756769 0.635 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr14_-_81893734 0.618 ENST00000555447.1
STON2
stonin 2
chr16_+_30080857 0.611 ENST00000565355.1
ALDOA
aldolase A, fructose-bisphosphate
chr1_-_65533390 0.610 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr2_+_166326157 0.608 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3


cysteine-serine-rich nuclear protein 3


chr15_-_95870348 0.594 ENST00000556899.1
CTD-2536I1.1
CTD-2536I1.1
chr13_+_36050881 0.583 ENST00000537702.1
NBEA
neurobeachin
chr19_+_37997812 0.580 ENST00000542455.1
ENST00000587143.1
ZNF793

zinc finger protein 793

chr15_-_74501360 0.574 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr12_-_86650045 0.562 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_28125638 0.553 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr8_-_22550691 0.511 ENST00000519492.1
EGR3
early growth response 3
chr9_-_73477826 0.490 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
TRPM3





transient receptor potential cation channel, subfamily M, member 3





chr6_+_32006159 0.486 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2


cytochrome P450, family 21, subfamily A, polypeptide 2


chr8_+_77316233 0.476 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr19_+_35849723 0.469 ENST00000594310.1
FFAR3
free fatty acid receptor 3
chr1_-_109584716 0.468 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47


WD repeat domain 47


chr1_-_109584768 0.437 ENST00000357672.3
WDR47
WD repeat domain 47
chr12_-_86650154 0.426 ENST00000552435.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_-_200323414 0.396 ENST00000443023.1
SATB2
SATB homeobox 2
chr14_-_24733444 0.395 ENST00000560478.1
ENST00000560443.1
TGM1

transglutaminase 1

chr8_-_143961236 0.391 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1


cytochrome P450, family 11, subfamily B, polypeptide 1


chr2_+_121493717 0.390 ENST00000418323.1
GLI2
GLI family zinc finger 2
chr9_+_40028620 0.385 ENST00000426179.1
AL353791.1
AL353791.1
chr12_-_88423164 0.385 ENST00000298699.2
ENST00000550553.1
C12orf50

chromosome 12 open reading frame 50

chr7_-_144107320 0.369 ENST00000483238.1
ENST00000467773.1
NOBOX

NOBOX oogenesis homeobox

chr11_-_55905194 0.364 ENST00000301529.1
OR8J3
olfactory receptor, family 8, subfamily J, member 3
chr8_+_77596014 0.361 ENST00000523885.1
ZFHX4
zinc finger homeobox 4
chr1_+_68150744 0.345 ENST00000370986.4
ENST00000370985.3
GADD45A

growth arrest and DNA-damage-inducible, alpha

chrX_-_65253506 0.336 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr7_-_100881041 0.324 ENST00000412417.1
ENST00000414035.1
CLDN15

claudin 15

chr11_+_47430133 0.324 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13




solute carrier family 39 (zinc transporter), member 13




chr1_-_109584608 0.304 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47



WD repeat domain 47



chr20_+_30467600 0.296 ENST00000375934.4
ENST00000375922.4
TTLL9

tubulin tyrosine ligase-like family, member 9

chr1_+_243419306 0.289 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr12_+_10658489 0.288 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chrX_+_95939711 0.282 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr7_-_14029283 0.262 ENST00000433547.1
ENST00000405192.2
ETV1

ets variant 1

chr18_-_53070913 0.256 ENST00000568186.1
ENST00000564228.1
TCF4

transcription factor 4

chr9_-_73029540 0.256 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr7_-_78400364 0.256 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_102267953 0.241 ENST00000523694.2
ENST00000507176.1
PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

chr9_-_127269661 0.235 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr3_-_98619999 0.228 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr17_+_43239231 0.210 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2


hexamethylene bis-acetamide inducible 2


chr5_+_145826867 0.208 ENST00000296702.5
ENST00000394421.2
TCERG1

transcription elongation regulator 1

chr12_+_7022909 0.188 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr15_-_95870310 0.182 ENST00000508732.2
CTD-2536I1.1
CTD-2536I1.1
chr2_-_49381646 0.172 ENST00000346173.3
ENST00000406846.2
FSHR

follicle stimulating hormone receptor

chr5_-_145895753 0.171 ENST00000311104.2
GPR151
G protein-coupled receptor 151
chr17_+_7758374 0.167 ENST00000301599.6
ENST00000574668.1
TMEM88

transmembrane protein 88

chr8_-_143999259 0.166 ENST00000323110.2
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chrX_+_95939638 0.166 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2


diaphanous-related formin 2


chr12_+_57482877 0.164 ENST00000342556.6
ENST00000357680.4
NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2)

chr2_-_44588694 0.163 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr12_-_86650077 0.163 ENST00000552808.2
ENST00000547225.1
MGAT4C

mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)

chr3_+_191046810 0.155 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr2_-_200322723 0.149 ENST00000417098.1
SATB2
SATB homeobox 2
chr2_-_44588679 0.123 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr2_-_49381572 0.108 ENST00000454032.1
ENST00000304421.4
FSHR

follicle stimulating hormone receptor

chr17_+_43239191 0.097 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chrY_+_26997726 0.087 ENST00000382296.2
DAZ4
deleted in azoospermia 4
chr19_+_44645731 0.068 ENST00000426739.2
ZNF234
zinc finger protein 234
chr1_-_43833628 0.063 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr7_-_78400598 0.052 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_+_125562370 0.051 ENST00000277309.2
OR1K1
olfactory receptor, family 1, subfamily K, member 1
chr19_+_47421933 0.040 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr16_-_54972581 0.034 ENST00000559802.1
ENST00000558156.1
CTD-3032H12.1

CTD-3032H12.1

chr5_+_154181816 0.027 ENST00000518677.1
LARP1
La ribonucleoprotein domain family, member 1
chr17_+_58755184 0.016 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr1_+_36621174 0.009 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr9_-_26947220 0.007 ENST00000520884.1
PLAA
phospholipase A2-activating protein

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499) negative regulation of keratinocyte differentiation(GO:0045617) female genitalia morphogenesis(GO:0048807)
1.2 12.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.8 6.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) negative regulation of cell volume(GO:0045794)
0.7 11.7 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.7 2.0 GO:1904396 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.7 3.3 GO:0072015 intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) pulmonary artery morphogenesis(GO:0061156) cell proliferation involved in mesonephros development(GO:0061209) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) negative regulation of mesonephros development(GO:0061218) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) BMP signaling pathway involved in nephric duct formation(GO:0071893) glomerular visceral epithelial cell development(GO:0072015) comma-shaped body morphogenesis(GO:0072049) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) glomerulus morphogenesis(GO:0072102) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104) mesenchymal cell proliferation involved in ureteric bud development(GO:0072138) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) metanephric comma-shaped body morphogenesis(GO:0072278) glomerular epithelial cell development(GO:0072310) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.6 2.4 GO:0060649 mammary gland bud elongation(GO:0060649) nipple sheath formation(GO:0060659)
0.6 3.5 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.5 2.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.4 2.8 GO:0001955 blood vessel maturation(GO:0001955)
0.4 3.9 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.3 1.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 24.7 GO:0030510 regulation of BMP signaling pathway(GO:0030510)
0.3 1.0 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in heart development(GO:0060973)
0.3 4.8 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.3 1.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 27.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 0.8 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 2.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 2.6 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.2 1.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.2 3.9 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.2 8.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 7.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.2 8.4 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.2 3.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 4.5 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.2 2.6 GO:0072283 mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) metanephric renal vesicle morphogenesis(GO:0072283)
0.1 0.4 GO:0007350 blastoderm segmentation(GO:0007350)
0.1 2.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 11.0 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.1 1.8 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 2.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 4.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.9 GO:0010842 retina layer formation(GO:0010842)
0.1 2.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 1.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 2.0 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.1 1.4 GO:0060674 placenta blood vessel development(GO:0060674)
0.1 0.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 2.0 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.1 3.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 3.0 GO:0071772 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.7 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 4.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0043113 receptor clustering(GO:0043113)
0.0 1.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.3 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 6.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0021879 forebrain neuron differentiation(GO:0021879)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.5 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 3.6 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.2 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.8 GO:0048477 oogenesis(GO:0048477)
0.0 1.6 GO:0043010 camera-type eye development(GO:0043010)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0019718 obsolete rough microsome(GO:0019718)
1.1 27.3 GO:0032982 myosin filament(GO:0032982)
0.5 8.2 GO:0005606 laminin-1 complex(GO:0005606)
0.4 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 2.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.0 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.2 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 8.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 28.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 6.6 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 3.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.6 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 11.2 GO:0005938 cell cortex(GO:0005938)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 7.7 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 4.5 GO:0030427 growth cone(GO:0030426) site of polarized growth(GO:0030427)
0.0 6.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 13.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.4 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 3.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0043197 dendritic spine(GO:0043197)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 4.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 5.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
2.5 27.3 GO:0031432 titin binding(GO:0031432)
1.5 12.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 6.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.4 11.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 2.8 GO:0044325 ion channel binding(GO:0044325)
0.3 3.3 GO:0070700 BMP receptor binding(GO:0070700)
0.3 3.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3 1.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 2.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 7.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 4.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 1.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 0.6 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507)
0.2 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 8.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 2.6 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.2 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 4.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.7 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 7.7 GO:0002039 p53 binding(GO:0002039)
0.1 14.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 3.9 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 5.9 GO:0005179 hormone activity(GO:0005179)
0.1 1.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 2.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 3.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 9.1 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.0 0.3 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 2.2 GO:0005057 receptor signaling protein activity(GO:0005057)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.