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Illumina Body Map 2: averaged replicates

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Results for HOXA5

Z-value: 1.28

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Transcription factors associated with HOXA5

Gene Symbol Gene ID Gene Info
ENSG00000106004.4 homeobox A5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA5hg19_v2_chr7_-_27183263_27183287-0.402.3e-02Click!

Activity profile of HOXA5 motif

Sorted Z-values of HOXA5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_21186144 4.06 ENST00000377119.1
nebulette
chr6_-_154677900 3.05 ENST00000265198.4
ENST00000520261.1
interaction protein for cytohesin exchange factors 1
chr6_-_154677866 2.74 ENST00000367220.4
interaction protein for cytohesin exchange factors 1
chr3_+_35721106 2.66 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
cAMP-regulated phosphoprotein, 21kDa
chr14_+_93389425 2.43 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chrX_+_54947229 2.13 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
trophinin
chr6_+_123100853 1.91 ENST00000356535.4
fatty acid binding protein 7, brain
chr10_-_69425399 1.84 ENST00000330298.6
catenin (cadherin-associated protein), alpha 3
chr4_-_168155169 1.84 ENST00000534949.1
ENST00000535728.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr9_+_77112244 1.82 ENST00000376896.3
RAR-related orphan receptor B
chrX_+_75648046 1.76 ENST00000361470.2
melanoma antigen family E, 1
chr6_+_124125286 1.71 ENST00000368416.1
ENST00000368417.1
ENST00000546092.1
Na+/K+ transporting ATPase interacting 2
chr6_+_13182751 1.66 ENST00000415087.1
phosphatase and actin regulator 1
chr1_-_149889382 1.59 ENST00000369145.1
ENST00000369146.3
synaptic vesicle glycoprotein 2A
chr3_+_238427 1.57 ENST00000397491.2
cell adhesion molecule L1-like
chr8_-_123139423 1.56 ENST00000523792.1
RP11-398G24.2
chr1_+_204839959 1.55 ENST00000404076.1
neurofascin
chr10_+_18240834 1.50 ENST00000377371.3
ENST00000539911.1
solute carrier family 39 (zinc transporter), member 12
chr6_-_116575226 1.47 ENST00000420283.1
TSPY-like 4
chr3_+_173116225 1.46 ENST00000457714.1
neuroligin 1
chr2_+_166095898 1.45 ENST00000424833.1
ENST00000375437.2
ENST00000357398.3
sodium channel, voltage-gated, type II, alpha subunit
chr6_-_44400720 1.41 ENST00000595057.1
AL133262.1
chrX_+_72062802 1.38 ENST00000373533.1
DMRT-like family C1B
chr5_+_140235469 1.37 ENST00000506939.2
ENST00000307360.5
protocadherin alpha 10
chr3_+_35721130 1.37 ENST00000432450.1
cAMP-regulated phosphoprotein, 21kDa
chr10_+_18240814 1.32 ENST00000377374.4
solute carrier family 39 (zinc transporter), member 12
chr2_+_155555201 1.32 ENST00000544049.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr1_+_197237352 1.31 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
crumbs homolog 1 (Drosophila)
chrX_-_72097698 1.26 ENST00000373530.1
DMRT-like family C1
chr14_+_32963433 1.24 ENST00000554410.1
A kinase (PRKA) anchor protein 6
chr18_+_13611431 1.23 ENST00000587757.1
low density lipoprotein receptor class A domain containing 4
chr3_+_238273 1.22 ENST00000256509.2
cell adhesion molecule L1-like
chr3_+_35721182 1.19 ENST00000413378.1
ENST00000417925.1
cAMP-regulated phosphoprotein, 21kDa
chr8_+_75262629 1.17 ENST00000434412.2
ganglioside induced differentiation associated protein 1
chr5_+_132149017 1.17 ENST00000378693.2
sosondowah ankyrin repeat domain family member A
chr4_+_184826418 1.15 ENST00000308497.4
ENST00000438269.1
storkhead box 2
chr20_+_4667094 1.14 ENST00000424424.1
ENST00000457586.1
prion protein
chr16_-_62070305 1.11 ENST00000584337.1
cadherin 8, type 2
chr1_+_87012753 1.10 ENST00000370563.3
chloride channel accessory 4
chr6_+_168418553 1.09 ENST00000354419.2
ENST00000351261.3
kinesin family member 25
chr12_-_54653313 1.09 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr18_+_59000815 1.06 ENST00000262717.4
cadherin 20, type 2
chr1_+_177140633 1.01 ENST00000361539.4
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr16_-_66764119 1.01 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr5_+_140723601 1.00 ENST00000253812.6
protocadherin gamma subfamily A, 3
chr19_+_18794470 0.99 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr10_-_61495760 0.98 ENST00000395347.1
solute carrier family 16, member 9
chr1_+_84609944 0.98 ENST00000370685.3
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_140207536 0.98 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr5_+_140552218 0.96 ENST00000231137.3
protocadherin beta 7
chr6_-_152623231 0.92 ENST00000540663.1
ENST00000537033.1
spectrin repeat containing, nuclear envelope 1
chr14_+_65878650 0.90 ENST00000555559.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr10_+_18549645 0.90 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_58515417 0.90 ENST00000360816.3
family with sequence similarity 217, member B
chrX_+_10124977 0.90 ENST00000380833.4
chloride channel, voltage-sensitive 4
chr2_-_40657397 0.89 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_-_62358690 0.88 ENST00000475839.1
FEZ family zinc finger 2
chr4_-_142054590 0.87 ENST00000306799.3
ring finger protein 150
chr2_-_113594279 0.85 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr11_+_20044375 0.85 ENST00000525322.1
ENST00000530408.1
neuron navigator 2
chr3_+_238456 0.84 ENST00000427688.1
cell adhesion molecule L1-like
chrX_+_102024075 0.83 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr18_+_616672 0.81 ENST00000338387.7
clusterin-like 1 (retinal)
chr14_+_65878565 0.81 ENST00000556518.1
ENST00000557164.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr20_-_34638841 0.80 ENST00000565493.1
long intergenic non-protein coding RNA 657
chr8_-_141774467 0.80 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr20_+_4666882 0.79 ENST00000379440.4
ENST00000430350.2
prion protein
chr4_-_36245561 0.79 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_143567262 0.78 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr12_+_25205568 0.73 ENST00000548766.1
ENST00000556887.1
lymphoid-restricted membrane protein
chr18_+_616711 0.73 ENST00000579494.1
clusterin-like 1 (retinal)
chr6_-_143266297 0.69 ENST00000367603.2
human immunodeficiency virus type I enhancer binding protein 2
chr12_-_11150474 0.68 ENST00000538986.1
taste receptor, type 2, member 20
chr10_-_127505167 0.67 ENST00000368786.1
uroporphyrinogen III synthase
chr1_-_227505289 0.67 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr10_-_75226166 0.66 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr3_-_178103144 0.65 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
chr10_-_7708918 0.64 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr12_+_25205628 0.64 ENST00000554942.1
lymphoid-restricted membrane protein
chr7_-_35013217 0.64 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr3_-_145940126 0.61 ENST00000498625.1
phospholipid scramblase 4
chr15_-_67351586 0.61 ENST00000558071.1
RP11-798K3.2
chr15_+_77713299 0.60 ENST00000559099.1
high mobility group 20A
chr10_+_101089107 0.60 ENST00000446890.1
ENST00000370528.3
cyclin M1
chr4_-_113627966 0.60 ENST00000505632.1
RP11-148B6.2
chr9_+_140125385 0.59 ENST00000361134.2
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr1_-_244006528 0.58 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr1_-_170043709 0.57 ENST00000367767.1
ENST00000361580.2
ENST00000538366.1
kinesin-associated protein 3
chr4_-_164534657 0.56 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr15_+_77713222 0.54 ENST00000558176.1
high mobility group 20A
chr4_+_26324474 0.53 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_232651312 0.52 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr9_+_44868935 0.50 ENST00000448436.2
RP11-160N1.10
chr4_+_158493642 0.50 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr4_-_114438763 0.49 ENST00000509594.1
calcium/calmodulin-dependent protein kinase II delta
chrX_-_33229429 0.48 ENST00000420596.1
ENST00000448370.1
dystrophin
chr19_-_44384291 0.48 ENST00000324394.6
zinc finger protein 404
chr15_-_73925575 0.47 ENST00000562924.1
ENST00000563691.1
ENST00000565325.1
ENST00000542234.1
neuroplastin
chr6_+_155537771 0.46 ENST00000275246.7
T-cell lymphoma invasion and metastasis 2
chr12_+_111051832 0.46 ENST00000550703.2
ENST00000551590.1
tectonic family member 1
chr8_-_66750978 0.45 ENST00000523253.1
phosphodiesterase 7A
chr5_+_76326187 0.43 ENST00000312916.7
ENST00000506806.1
angiogenic factor with G patch and FHA domains 1
chr8_+_38065104 0.43 ENST00000521311.1
BCL2-associated athanogene 4
chr4_-_152682129 0.41 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112 homolog (yeast)
chr20_-_58515344 0.41 ENST00000370996.3
protein phosphatase 1, regulatory subunit 3D
chr3_+_107364683 0.41 ENST00000413213.1
bobby sox homolog (Drosophila)
chr15_-_102463298 0.40 ENST00000326183.3
olfactory receptor, family 4, subfamily F, member 4
chr13_+_76378305 0.40 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr14_+_67291158 0.40 ENST00000555456.1
gephyrin
chr11_+_20044096 0.39 ENST00000533917.1
neuron navigator 2
chr3_-_62359180 0.39 ENST00000283268.3
FEZ family zinc finger 2
chr3_-_78719376 0.39 ENST00000495961.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_-_207078154 0.38 ENST00000447845.1
G protein-coupled receptor 1
chr2_+_102508955 0.38 ENST00000414004.2
FLJ20373
chr12_+_74931551 0.38 ENST00000519948.2
ataxin 7-like 3B
chr12_+_25205666 0.38 ENST00000547044.1
lymphoid-restricted membrane protein
chr2_-_207082748 0.38 ENST00000407325.2
ENST00000411719.1
G protein-coupled receptor 1
chr4_-_16675930 0.37 ENST00000503178.2
LIM domain binding 2
chr14_-_20801427 0.37 ENST00000557665.1
ENST00000358932.4
ENST00000353689.4
cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr2_+_30670209 0.37 ENST00000497423.1
ENST00000476535.1
lysocardiolipin acyltransferase 1
chr15_-_73925651 0.36 ENST00000545878.1
ENST00000287226.8
ENST00000345330.4
neuroplastin
chr10_-_52008313 0.36 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chrX_+_55478538 0.35 ENST00000342972.1
melanoma antigen family H, 1
chr17_+_74733744 0.35 ENST00000586689.1
ENST00000587661.1
ENST00000593181.1
ENST00000336509.4
ENST00000355954.3
major facilitator superfamily domain containing 11
chr19_+_53761545 0.35 ENST00000341702.3
vomeronasal 1 receptor 2
chr20_+_33292068 0.35 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr7_+_26438187 0.35 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr10_-_97200772 0.34 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr11_-_18610246 0.34 ENST00000379387.4
ENST00000541984.1
UEV and lactate/malate dehyrogenase domains
chr11_-_16419067 0.33 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr11_-_33744256 0.33 ENST00000415002.2
ENST00000437761.2
ENST00000445143.2
CD59 molecule, complement regulatory protein
chr2_-_55496344 0.31 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr3_+_130569429 0.30 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_140175987 0.30 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
chr11_+_33061543 0.30 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr2_-_214017151 0.30 ENST00000452786.1
IKAROS family zinc finger 2 (Helios)
chr7_+_44084233 0.28 ENST00000448521.1
drebrin-like
chr1_-_154150651 0.28 ENST00000302206.5
tropomyosin 3
chr15_-_53002007 0.27 ENST00000561490.1
family with sequence similarity 214, member A
chr17_-_33446820 0.27 ENST00000592577.1
ENST00000590016.1
ENST00000345365.6
ENST00000360276.3
ENST00000357906.3
RAD51 paralog D
chr11_-_71823266 0.27 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
anaphase promoting complex subunit 15
chr18_-_33709268 0.26 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr10_+_123951957 0.26 ENST00000514539.1
transforming, acidic coiled-coil containing protein 2
chr5_+_140227357 0.26 ENST00000378122.3
protocadherin alpha 9
chr8_+_92261516 0.26 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr17_-_33446735 0.25 ENST00000460118.2
ENST00000335858.7
RAD51 paralog D
chr6_-_2751146 0.24 ENST00000268446.5
ENST00000274643.7
myosin light chain kinase family, member 4
chr5_+_66300446 0.22 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr8_-_41166953 0.22 ENST00000220772.3
secreted frizzled-related protein 1
chr7_-_99716914 0.22 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_+_33290491 0.22 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
nuclear transcription factor, X-box binding 1
chr8_-_90769422 0.21 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
chr2_-_207078086 0.20 ENST00000442134.1
G protein-coupled receptor 1
chr1_+_153950202 0.20 ENST00000608236.1
RP11-422P24.11
chr18_+_68002675 0.20 ENST00000584919.1
Uncharacterized protein
chr11_+_9685604 0.20 ENST00000447399.2
ENST00000318950.6
SWAP switching B-cell complex 70kDa subunit
chr14_+_102276132 0.19 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_106817137 0.19 ENST00000510876.1
integrator complex subunit 12
chr11_-_33744487 0.19 ENST00000426650.2
CD59 molecule, complement regulatory protein
chr2_+_30670127 0.19 ENST00000540623.1
ENST00000476038.1
lysocardiolipin acyltransferase 1
chr2_+_227771404 0.19 ENST00000409053.1
rhomboid domain containing 1
chr4_-_103749205 0.18 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr12_+_25205446 0.17 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr6_-_28554977 0.17 ENST00000452236.2
SCAN domain containing 3
chr1_+_160370344 0.17 ENST00000368061.2
VANGL planar cell polarity protein 2
chr10_-_115904361 0.17 ENST00000428953.1
ENST00000543782.1
chromosome 10 open reading frame 118
chr7_-_99716940 0.16 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr14_+_24025462 0.16 ENST00000556015.1
ENST00000554970.1
ENST00000554789.1
thiamine triphosphatase
chr19_+_41768401 0.16 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr5_-_131879205 0.15 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr7_+_155437341 0.15 ENST00000401878.3
ENST00000392759.3
RNA binding motif protein 33
chr1_+_100111580 0.14 ENST00000605497.1
palmdelphin
chr21_+_44073860 0.13 ENST00000335512.4
ENST00000539837.1
ENST00000291539.6
ENST00000380328.2
ENST00000398232.3
ENST00000398234.3
ENST00000398236.3
ENST00000328862.6
ENST00000335440.6
ENST00000398225.3
ENST00000398229.3
ENST00000398227.3
phosphodiesterase 9A
chr7_+_44084262 0.12 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
drebrin-like
chr6_-_34216766 0.12 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
chromosome 6 open reading frame 1
chr3_+_12392971 0.12 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr4_+_25378912 0.12 ENST00000510092.1
ENST00000505991.1
anaphase promoting complex subunit 4
chr21_-_40033618 0.12 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chr6_+_143447322 0.11 ENST00000458219.1
androgen-induced 1
chr11_+_12399071 0.11 ENST00000539723.1
ENST00000550549.1
parvin, alpha
chr1_+_100111479 0.11 ENST00000263174.4
palmdelphin
chr19_+_45174994 0.10 ENST00000403660.3
carcinoembryonic antigen-related cell adhesion molecule 19
chr13_+_76378407 0.09 ENST00000447038.1
LIM domain 7
chr8_+_94712895 0.09 ENST00000523453.1
ENST00000520955.1
family with sequence similarity 92, member A1
chr2_+_30670077 0.09 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
lysocardiolipin acyltransferase 1
chr11_-_115375107 0.08 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
cell adhesion molecule 1
chrX_-_65253506 0.07 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr4_+_86525299 0.07 ENST00000512201.1
Rho GTPase activating protein 24
chr9_-_123342415 0.07 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5 regulatory subunit associated protein 2
chr14_+_102276192 0.06 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr19_-_35264089 0.05 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
zinc finger protein 599
chr5_+_69321074 0.05 ENST00000380751.5
ENST00000380750.3
ENST00000503931.1
ENST00000506542.1
small EDRK-rich factor 1B (centromeric)
chr6_-_24666819 0.05 ENST00000341060.3
tyrosyl-DNA phosphodiesterase 2
chr4_-_103746683 0.04 ENST00000504211.1
ENST00000508476.1
ubiquitin-conjugating enzyme E2D 3
chr1_+_171283331 0.04 ENST00000367749.3
flavin containing monooxygenase 4
chr12_-_91574142 0.04 ENST00000547937.1
decorin
chr14_+_102276209 0.04 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
protein phosphatase 2, regulatory subunit B', gamma
chr17_+_74734052 0.03 ENST00000590514.1
major facilitator superfamily domain containing 11
chr8_-_122653630 0.03 ENST00000303924.4
hyaluronan synthase 2
chr16_-_72128270 0.03 ENST00000426362.2
thioredoxin-like 4B

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:1901899 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.4 1.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.4 1.9 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.4 1.5 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.4 1.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.3 1.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 0.9 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.2 0.7 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 5.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.8 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.6 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.2 1.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.8 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.2 GO:0021564 vagus nerve development(GO:0021564)
0.1 3.1 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.5 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.1 1.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 4.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.0 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 1.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 3.6 GO:0035640 exploration behavior(GO:0035640)
0.1 1.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.1 1.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.5 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.5 GO:0021523 somatic motor neuron differentiation(GO:0021523) protein localization to ciliary transition zone(GO:1904491)
0.1 0.6 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.9 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.5 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.6 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.7 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.9 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.6 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.8 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 1.0 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.8 GO:0097369 sodium ion import(GO:0097369)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 9.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.8 GO:0051642 centrosome localization(GO:0051642)
0.0 4.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.8 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 1.9 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.6 GO:1990075 kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075)
0.1 2.4 GO:0042583 chromaffin granule(GO:0042583)
0.1 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.1 1.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.6 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.8 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 5.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 1.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 1.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 1.3 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.3 1.9 GO:1903135 cupric ion binding(GO:1903135)
0.3 5.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 0.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 1.3 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.2 0.8 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.8 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 4.1 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 3.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 1.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.9 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.8 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.4 GO:0002020 protease binding(GO:0002020)
0.0 5.3 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 2.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins