ISMARA results: HOXA9

Project

Illumina Body Map 2: averaged replicates

Navigation

Downloads

Results for HOXA9

Z-value: 1.62

Motif logo

Transcription factors associated with HOXA9

Gene Symbol	Gene ID	Gene Info
HOXA9 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000078399.11	homeobox A9

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXA9	hg19_v2_chr7_-_27205136_27205164	0.25	1.7e-01	Click!

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_88427568 Show fit	4.59	ENST00000393750.3 ENST00000295834.3	FABP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 1, liver
chr2_-_224467002 Show fit	3.49	ENST00000421386.1 ENST00000433889.1	SCG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	secretogranin II
chr13_+_53602894 Show fit	2.74	ENST00000219022.2	OLFM4 Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactomedin 4
chr1_+_50575292 Show fit	2.70	ENST00000371821.1 ENST00000371819.1	ELAVL4 Ensembl NCBI GeneCards UniProt NextProt Show fit	ELAV like neuron-specific RNA binding protein 4
chr2_-_224467093 Show fit	2.63	ENST00000305409.2	SCG2 Ensembl NCBI GeneCards UniProt NextProt Show fit	secretogranin II
chrX_+_65384182 Show fit	2.37	ENST00000441993.2 ENST00000419594.1	HEPH Ensembl NCBI GeneCards UniProt NextProt Show fit	hephaestin
chr2_-_154335300 Show fit	2.36	ENST00000325926.3	RPRM Ensembl NCBI GeneCards UniProt NextProt Show fit	reprimo, TP53 dependent G2 arrest mediator candidate
chr15_+_33022885 Show fit	2.35	ENST00000322805.4	GREM1 Ensembl NCBI GeneCards UniProt NextProt Show fit	gremlin 1, DAN family BMP antagonist
chr10_+_85933494 Show fit	2.26	ENST00000372126.3	C10orf99 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 10 open reading frame 99
chr7_-_92855762 Show fit	2.16	ENST00000453812.2 ENST00000394468.2	HEPACAM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	HEPACAM family member 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	6.1	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.2	5.4	GO:0090179	planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2	5.4	GO:0006825	copper ion transport(GO:0006825)
0.4	4.8	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.4	4.7	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3	4.6	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.3	3.5	GO:0045329	carnitine biosynthetic process(GO:0045329)
0.1	3.1	GO:0051764	actin crosslink formation(GO:0051764)
0.1	3.0	GO:0052695	cellular glucuronidation(GO:0052695)
0.3	2.7	GO:2000389	regulation of neutrophil extravasation(GO:2000389)

Showing 1 to 10 of 136 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.1	GO:0031045	dense core granule(GO:0031045)
0.3	4.6	GO:0045179	apical cortex(GO:0045179)
0.1	3.5	GO:0030673	axolemma(GO:0030673)
0.0	3.5	GO:0043197	dendritic spine(GO:0043197)
0.0	2.4	GO:0043198	dendritic shaft(GO:0043198)
0.0	2.3	GO:0035580	specific granule lumen(GO:0035580)
0.0	2.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.7	GO:0031941	filamentous actin(GO:0031941)
0.0	1.6	GO:0044295	axonal growth cone(GO:0044295)
0.5	1.4	GO:0034686	integrin alphav-beta8 complex(GO:0034686)

Showing 1 to 10 of 46 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.0	GO:0042056	chemoattractant activity(GO:0042056)
0.5	5.4	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5	4.7	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
0.7	4.6	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	4.0	GO:0017091	AU-rich element binding(GO:0017091)
0.9	3.5	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2	3.5	GO:0036122	BMP binding(GO:0036122)
0.1	3.0	GO:0001972	retinoic acid binding(GO:0001972)
0.0	2.9	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	2.8	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)

Showing 1 to 10 of 95 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.5	PID BMP PATHWAY	BMP receptor signaling
0.0	3.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	2.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	1.7	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	1.7	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.4	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	1.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.9	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network

Showing 1 to 10 of 11 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	4.8	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	4.7	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	4.3	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.1	3.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	2.5	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	2.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.9	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.7	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.7	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling

Showing 1 to 10 of 29 entries

Results for HOXA9

Z-value: 1.62

Motif logo

Transcription factors associated with HOXA9

Activity-expression correlation:

Activity profile of HOXA9 motif

Sorted Z-values of HOXA9 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA9

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: