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Illumina Body Map 2: averaged replicates

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Results for HOXB4_LHX9

Z-value: 1.29

Motif logo

Transcription factors associated with HOXB4_LHX9

Gene Symbol Gene ID Gene Info
ENSG00000182742.5 homeobox B4
ENSG00000143355.11 LIM homeobox 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB4hg19_v2_chr17_-_46657473_46657473-0.183.1e-01Click!
LHX9hg19_v2_chr1_+_197881592_1978816350.125.1e-01Click!

Activity profile of HOXB4_LHX9 motif

Sorted Z-values of HOXB4_LHX9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_14109841 4.30 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
chr2_+_182850551 3.52 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_+_26348429 3.28 ENST00000242729.2
sarcospan
chrX_+_43515467 3.27 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr12_+_101988627 3.20 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr14_-_80697396 3.15 ENST00000557010.1
deiodinase, iodothyronine, type II
chr17_-_39743139 3.14 ENST00000167586.6
keratin 14
chr4_+_119810134 3.08 ENST00000434046.2
synaptopodin 2
chr12_+_26348246 3.05 ENST00000422622.2
sarcospan
chr4_+_119809984 2.98 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr12_+_101988774 2.87 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chrX_-_15332665 2.82 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr10_+_6779326 2.75 ENST00000417112.1
RP11-554I8.2
chr9_+_95997205 2.74 ENST00000411624.1
WNK lysine deficient protein kinase 2
chr12_-_10978957 2.70 ENST00000240619.2
taste receptor, type 2, member 10
chr3_+_28390637 2.69 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr5_+_140557371 2.64 ENST00000239444.2
protocadherin beta 8
chr5_+_140593509 2.59 ENST00000341948.4
protocadherin beta 13
chr3_-_149095652 2.50 ENST00000305366.3
transmembrane 4 L six family member 1
chr17_+_20978854 2.49 ENST00000456235.1
AC087393.1
chrX_+_10126488 2.42 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
chloride channel, voltage-sensitive 4
chr12_-_22063787 2.28 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr1_-_190446759 2.26 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr19_+_54466179 2.17 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr3_-_20053741 2.14 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chrX_-_21776281 2.13 ENST00000379494.3
small muscle protein, X-linked
chr18_-_24443151 2.12 ENST00000440832.3
aquaporin 4
chrX_-_18690210 2.11 ENST00000379984.3
retinoschisin 1
chr4_-_186570679 1.99 ENST00000451974.1
sorbin and SH3 domain containing 2
chr12_+_26348582 1.98 ENST00000535504.1
sarcospan
chr17_-_10372875 1.97 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr2_-_161056802 1.96 ENST00000283249.2
ENST00000409872.1
integrin, beta 6
chr10_+_24755416 1.93 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr16_+_3184924 1.91 ENST00000574902.1
ENST00000396878.3
zinc finger protein 213
chr10_-_105845674 1.91 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr10_-_13043697 1.85 ENST00000378825.3
coiled-coil domain containing 3
chr5_-_35938674 1.77 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr1_+_160370344 1.75 ENST00000368061.2
VANGL planar cell polarity protein 2
chr1_-_67266939 1.75 ENST00000304526.2
insulin-like 5
chr4_+_169418255 1.66 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr17_-_42992856 1.66 ENST00000588316.1
ENST00000435360.2
ENST00000586793.1
ENST00000588735.1
ENST00000588037.1
ENST00000592320.1
ENST00000253408.5
glial fibrillary acidic protein
chr4_+_169418195 1.63 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr2_-_161056762 1.61 ENST00000428609.2
ENST00000409967.2
integrin, beta 6
chr21_+_33671160 1.59 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr20_-_56265680 1.59 ENST00000414037.1
prostate transmembrane protein, androgen induced 1
chr2_-_38466726 1.53 ENST00000450854.1
AC009229.5
chr10_-_27529486 1.53 ENST00000375888.1
acyl-CoA binding domain containing 5
chr11_-_128894053 1.47 ENST00000392657.3
Rho GTPase activating protein 32
chrX_-_21676442 1.43 ENST00000379499.2
kelch-like family member 34
chr3_-_58613323 1.42 ENST00000474531.1
ENST00000465970.1
family with sequence similarity 107, member A
chr11_-_89541743 1.42 ENST00000329758.1
tripartite motif containing 49
chr16_+_3185125 1.39 ENST00000576416.1
zinc finger protein 213
chr13_+_110958124 1.39 ENST00000400163.2
collagen, type IV, alpha 2
chr4_-_16675930 1.36 ENST00000503178.2
LIM domain binding 2
chr1_-_112903150 1.32 ENST00000427290.1
RP5-965F6.2
chr1_-_211307404 1.32 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr14_+_20187174 1.28 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chr5_+_81575281 1.28 ENST00000380167.4
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr11_-_46408107 1.27 ENST00000433765.2
cholinergic receptor, muscarinic 4
chr11_+_12766583 1.24 ENST00000361985.2
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr4_-_159956333 1.24 ENST00000434826.2
chromosome 4 open reading frame 45
chr8_-_1922789 1.24 ENST00000521498.1
RP11-439C15.4
chr17_+_1674982 1.23 ENST00000572048.1
ENST00000573763.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_164796269 1.23 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr10_-_105845536 1.21 ENST00000393211.3
collagen, type XVII, alpha 1
chr9_+_124329336 1.20 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr18_+_5748793 1.18 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr2_+_187454749 1.18 ENST00000261023.3
ENST00000374907.3
integrin, alpha V
chr11_-_63376013 1.17 ENST00000540943.1
phospholipase A2, group XVI
chr9_+_12695702 1.16 ENST00000381136.2
tyrosinase-related protein 1
chr5_+_36606700 1.15 ENST00000416645.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_+_1225470 1.15 ENST00000324642.3
ENST00000296821.4
solute carrier family 6 (neutral amino acid transporter), member 18
chr13_+_111837279 1.13 ENST00000467053.1
Rho guanine nucleotide exchange factor (GEF) 7
chr1_-_72566613 1.13 ENST00000306821.3
neuronal growth regulator 1
chr1_+_192605252 1.12 ENST00000391995.2
ENST00000543215.1
regulator of G-protein signaling 13
chr6_+_53964336 1.12 ENST00000447836.2
ENST00000511678.1
muscular LMNA-interacting protein
chr2_+_182850743 1.10 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_-_75415825 1.09 ENST00000394810.2
synaptopodin 2-like
chr4_+_157997273 1.08 ENST00000541722.1
ENST00000512619.1
glycine receptor, beta
chr9_-_28670283 1.08 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr11_+_89764274 1.05 ENST00000448984.1
ENST00000432771.1
tripartite motif containing 49C
chr6_+_29429217 1.04 ENST00000396792.2
olfactory receptor, family 2, subfamily H, member 1
chr2_-_27886676 1.01 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr13_-_36050819 1.00 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr6_+_129204337 0.99 ENST00000421865.2
laminin, alpha 2
chr5_-_41794313 0.99 ENST00000512084.1
3-oxoacid CoA transferase 1
chr2_-_74618907 0.99 ENST00000421392.1
ENST00000437375.1
dynactin 1
chr5_-_176889381 0.98 ENST00000393563.4
ENST00000512501.1
drebrin 1
chr6_+_47749718 0.98 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
opsin 5
chr14_+_32798547 0.97 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr15_+_62853562 0.96 ENST00000561311.1
talin 2
chr12_+_8309630 0.96 ENST00000396570.3
zinc finger protein 705A
chr4_-_138453606 0.95 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr6_+_28227063 0.95 ENST00000343684.3
NFKB activating protein-like
chr2_-_142888573 0.95 ENST00000434794.1
low density lipoprotein receptor-related protein 1B
chr16_+_15489629 0.94 ENST00000396385.3
MPV17 mitochondrial membrane protein-like
chr12_-_25348007 0.94 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
cancer susceptibility candidate 1
chr12_-_8803128 0.93 ENST00000543467.1
microfibrillar associated protein 5
chr19_-_14064114 0.93 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
podocan-like 1
chr17_-_4938712 0.92 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr15_+_54901540 0.90 ENST00000539562.2
unc-13 homolog C (C. elegans)
chr11_+_60383204 0.90 ENST00000412599.1
ENST00000320202.4
long intergenic non-protein coding RNA 301
chr3_+_111717511 0.90 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr15_+_84115868 0.89 ENST00000427482.2
SH3-domain GRB2-like 3
chr2_+_27886330 0.89 ENST00000326019.6
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr3_-_160823158 0.88 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_+_65265141 0.88 ENST00000534336.1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chrX_-_138790348 0.86 ENST00000414978.1
ENST00000519895.1
MCF.2 cell line derived transforming sequence
chr4_-_46126093 0.85 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr5_-_102898465 0.85 ENST00000507423.1
ENST00000230792.2
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr18_-_3219847 0.85 ENST00000261606.7
myomesin 1
chr8_-_124553437 0.85 ENST00000517956.1
ENST00000443022.2
F-box protein 32
chr3_-_160823040 0.83 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr6_+_168418553 0.82 ENST00000354419.2
ENST00000351261.3
kinesin family member 25
chr4_+_147145709 0.81 ENST00000504313.1
Uncharacterized protein
chr10_-_128110441 0.81 ENST00000456514.1
long intergenic non-protein coding RNA 601
chrX_-_142605301 0.80 ENST00000370503.2
SPANX family, member N3
chr16_-_52061283 0.80 ENST00000566314.1
chromosome 16 open reading frame 97
chr11_-_107729887 0.80 ENST00000525815.1
solute carrier family 35, member F2
chr8_+_50824233 0.80 ENST00000522124.1
syntrophin, gamma 1
chr5_+_175288631 0.80 ENST00000509837.1
complexin 2
chr19_-_36001113 0.80 ENST00000434389.1
dermokine
chr12_+_81110684 0.80 ENST00000228644.3
myogenic factor 5
chr11_-_107729504 0.80 ENST00000265836.7
solute carrier family 35, member F2
chr15_-_72523924 0.80 ENST00000566809.1
ENST00000567087.1
ENST00000569050.1
ENST00000568883.1
pyruvate kinase, muscle
chr5_+_151338426 0.76 ENST00000524034.1
CTB-12O2.1
chr7_+_134528635 0.75 ENST00000445569.2
caldesmon 1
chr4_-_138453559 0.75 ENST00000511115.1
protocadherin 18
chr8_-_110986918 0.75 ENST00000297404.1
potassium channel, subfamily V, member 1
chr20_-_56647116 0.75 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
chr8_+_70476088 0.75 ENST00000525999.1
sulfatase 1
chr2_-_27886460 0.75 ENST00000404798.2
ENST00000405491.1
ENST00000464789.2
ENST00000406540.1
suppressor of Ty 7 (S. cerevisiae)-like
chr11_-_123814580 0.75 ENST00000321252.2
olfactory receptor, family 6, subfamily T, member 1
chr8_+_92261516 0.74 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr11_-_107729287 0.74 ENST00000375682.4
solute carrier family 35, member F2
chr8_+_105235572 0.74 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr6_-_49937338 0.74 ENST00000398718.1
defensin, beta 113
chr11_-_26593677 0.73 ENST00000527569.1
mucin 15, cell surface associated
chr22_-_32651326 0.73 ENST00000266086.4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_-_13372253 0.72 ENST00000316609.5
deleted in liver cancer 1
chr13_+_76413852 0.72 ENST00000533809.2
LIM domain 7
chr6_-_138060103 0.72 ENST00000411615.1
ENST00000419220.1
RP11-356I2.1
chr8_-_41166953 0.71 ENST00000220772.3
secreted frizzled-related protein 1
chr7_+_73868120 0.71 ENST00000265755.3
GTF2I repeat domain containing 1
chr10_-_118928543 0.71 ENST00000419373.2
RP11-501J20.2
chr1_-_231005310 0.71 ENST00000470540.1
chromosome 1 open reading frame 198
chr8_-_57359131 0.70 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
proenkephalin
chr10_+_18549645 0.70 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr20_+_42187682 0.70 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chrX_+_84258832 0.70 ENST00000373173.2
apolipoprotein O-like
chr5_-_126409159 0.69 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
chromosome 5 open reading frame 63
chr13_+_36050881 0.69 ENST00000537702.1
neurobeachin
chr12_-_23737534 0.69 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr11_-_26593649 0.69 ENST00000455601.2
mucin 15, cell surface associated
chr12_-_64062583 0.69 ENST00000542209.1
dpy-19-like 2 (C. elegans)
chr11_-_119991589 0.68 ENST00000526881.1
tripartite motif containing 29
chr4_-_46996424 0.67 ENST00000264318.3
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr4_+_169552748 0.67 ENST00000504519.1
ENST00000512127.1
palladin, cytoskeletal associated protein
chr3_-_149293990 0.67 ENST00000472417.1
WW domain containing transcription regulator 1
chr13_+_24144796 0.67 ENST00000403372.2
tumor necrosis factor receptor superfamily, member 19
chr11_-_16419067 0.66 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr3_+_111717600 0.66 ENST00000273368.4
transgelin 3
chr19_-_14945933 0.66 ENST00000322301.3
olfactory receptor, family 7, subfamily A, member 5
chr3_-_151034734 0.66 ENST00000260843.4
G protein-coupled receptor 87
chr16_-_66583994 0.65 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr14_+_72399833 0.65 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr16_-_66584059 0.65 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chr11_-_26593779 0.65 ENST00000529533.1
mucin 15, cell surface associated
chr8_+_39972170 0.65 ENST00000521257.1
RP11-359E19.2
chr1_-_31666767 0.65 ENST00000530145.1
Na+/K+ transporting ATPase interacting 1
chr1_+_212965170 0.64 ENST00000532324.1
ENST00000366974.4
ENST00000530441.1
ENST00000526641.1
ENST00000531963.1
ENST00000366973.4
ENST00000526997.1
ENST00000488246.2
TatD DNase domain containing 3
chr3_-_141719195 0.64 ENST00000397991.4
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_+_202091980 0.64 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr5_+_89770664 0.63 ENST00000503973.1
ENST00000399107.1
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr10_-_45803286 0.63 ENST00000536058.1
olfactory receptor, family 13, subfamily A, member 1
chr4_-_109541539 0.63 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34 antisense RNA 1 (head to head)
chr15_+_75970672 0.63 ENST00000435356.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr5_-_53115506 0.62 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1
chr6_+_78400375 0.62 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr3_+_111718036 0.62 ENST00000455401.2
transgelin 3
chr7_+_73868439 0.62 ENST00000424337.2
GTF2I repeat domain containing 1
chr1_+_62439037 0.62 ENST00000545929.1
InaD-like (Drosophila)
chr4_+_189376725 0.62 ENST00000510832.1
ENST00000510005.1
ENST00000503458.1
long intergenic non-protein coding RNA 1060
chr4_+_156587853 0.62 ENST00000506455.1
ENST00000511108.1
guanylate cyclase 1, soluble, alpha 3
chr16_-_1538765 0.61 ENST00000447419.2
ENST00000440447.2
pentraxin 4, long
chr11_+_327171 0.61 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr3_+_156009623 0.61 ENST00000389634.5
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr2_-_74618964 0.59 ENST00000417090.1
ENST00000409868.1
dynactin 1
chr8_-_30670384 0.59 ENST00000221138.4
ENST00000518243.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr16_+_15489603 0.59 ENST00000568766.1
ENST00000287594.7
Uncharacterized protein
MPV17 mitochondrial membrane protein-like
chr2_-_40680578 0.58 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_-_177116772 0.58 ENST00000280191.2
spermatogenesis associated 4
chr18_-_31603603 0.57 ENST00000586553.1
nucleolar protein 4
chr7_+_73868220 0.57 ENST00000455841.2
GTF2I repeat domain containing 1
chr2_-_43266680 0.57 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr8_-_101571933 0.57 ENST00000520311.1
ankyrin repeat domain 46
chr4_-_103749179 0.57 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr4_-_122686261 0.56 ENST00000337677.5
transmembrane protein 155
chr18_-_48346298 0.56 ENST00000398439.3
maestro
chrX_-_13835147 0.55 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.5 2.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.5 3.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.4 4.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.4 1.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.4 1.9 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.3 6.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.3 1.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.3 0.8 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 0.8 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 1.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.7 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.2 2.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 1.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.2 3.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.2 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.2 0.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.2 1.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 3.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 1.5 GO:0030242 pexophagy(GO:0030242)
0.2 1.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 1.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 1.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 1.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 4.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.4 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.7 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.8 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.5 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 1.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.5 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 1.0 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.2 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.6 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 3.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.6 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 4.6 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 1.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.8 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 2.5 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.7 GO:2001023 regulation of response to drug(GO:2001023)
0.1 1.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 7.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 3.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 2.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.2 GO:2000395 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 2.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.7 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.6 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 1.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.1 GO:0006833 water transport(GO:0006833)
0.1 1.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 1.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.8 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 2.0 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0014877 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 2.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 2.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.4 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.7 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 2.0 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.3 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 7.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 1.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 1.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 11.4 GO:0006936 muscle contraction(GO:0006936)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 4.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 2.3 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.2 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 1.2 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.9 GO:0097435 fibril organization(GO:0097435)
0.0 0.8 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0044793 negative regulation by host of viral process(GO:0044793) negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.4 GO:0051642 centrosome localization(GO:0051642)
0.0 0.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.6 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:0009593 detection of chemical stimulus(GO:0009593)
0.0 1.9 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.1 GO:0007631 feeding behavior(GO:0007631)
0.0 0.5 GO:0007588 excretion(GO:0007588)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 1.7 GO:0060187 cell pole(GO:0060187)
0.4 1.2 GO:1990032 parallel fiber(GO:1990032)
0.4 1.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.4 2.1 GO:0005927 muscle tendon junction(GO:0005927)
0.3 2.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 8.9 GO:0032982 myosin filament(GO:0032982)
0.2 1.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 0.8 GO:1902912 pyruvate kinase complex(GO:1902912)
0.2 9.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 0.5 GO:0043257 laminin-8 complex(GO:0043257)
0.2 0.5 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 1.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.0 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.9 GO:0044326 dendritic spine neck(GO:0044326)
0.1 3.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.8 GO:0030914 STAGA complex(GO:0030914)
0.1 0.9 GO:0044305 calyx of Held(GO:0044305)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.1 GO:0000322 storage vacuole(GO:0000322)
0.1 1.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.6 GO:1990635 proximal dendrite(GO:1990635)
0.1 15.3 GO:0030018 Z disc(GO:0030018)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.2 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.3 GO:0002177 manchette(GO:0002177)
0.1 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.0 1.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.9 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 3.3 GO:0045178 basal part of cell(GO:0045178)
0.0 4.2 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 6.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.0 GO:0005605 basal lamina(GO:0005605)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.6 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.5 1.6 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.5 16.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 3.1 GO:1990254 keratin filament binding(GO:1990254)
0.4 1.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.4 3.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.4 3.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.3 1.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 1.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 4.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.2 1.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.2 1.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.8 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 1.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.6 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 1.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.1 GO:0015250 water channel activity(GO:0015250)
0.1 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 2.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 1.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.5 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 2.4 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 1.0 GO:0005522 profilin binding(GO:0005522)
0.0 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 1.6 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 2.0 GO:0070840 dynein complex binding(GO:0070840)
0.0 1.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.2 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.1 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 4.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 6.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 1.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 3.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.6 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 1.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID MYC PATHWAY C-MYC pathway
0.0 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 6.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.1 REACTOME OPSINS Genes involved in Opsins
0.1 1.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 4.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 1.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 2.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 2.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 4.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 5.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 3.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation