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Illumina Body Map 2: averaged replicates

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Results for HOXB6_PRRX2

Z-value: 4.61

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Transcription factors associated with HOXB6_PRRX2

Gene Symbol Gene ID Gene Info
ENSG00000108511.8 HOXB6
ENSG00000167157.9 PRRX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB6hg19_v2_chr17_-_46682321_46682362-0.202.8e-01Click!
PRRX2hg19_v2_chr9_+_132427883_1324279510.029.1e-01Click!

Activity profile of HOXB6_PRRX2 motif

Sorted Z-values of HOXB6_PRRX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB6_PRRX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_7382745 31.40 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_16761007 24.82 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_50201327 24.41 ENST00000412315.1
NRXN1
neurexin 1
chr7_+_107110488 17.72 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr12_-_16761117 17.53 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_-_181160240 16.54 ENST00000460993.1
RP11-275H4.1
RP11-275H4.1
chr2_+_162272605 14.60 ENST00000389554.3
TBR1
T-box, brain, 1
chr18_+_32290218 13.99 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr5_-_88120083 13.73 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr1_-_217250231 13.39 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr13_-_84456527 13.33 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr5_-_88120151 12.71 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr8_+_85618155 12.47 ENST00000523850.1
ENST00000521376.1
RALYL
RALY RNA binding protein-like
chr11_-_16419067 12.19 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr2_-_224467093 12.00 ENST00000305409.2
SCG2
secretogranin II
chr1_-_216896780 11.46 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG
estrogen-related receptor gamma
chr2_-_183291741 10.86 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr11_-_8285405 10.81 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr7_-_31380502 10.76 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr3_-_73483055 10.69 ENST00000479530.1
PDZRN3
PDZ domain containing ring finger 3
chr3_+_35721106 10.38 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_16759440 10.38 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_53089538 10.35 ENST00000566777.1
TCF4
transcription factor 4
chr1_+_50569575 10.10 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr12_-_16759711 10.07 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_176733377 9.84 ENST00000505375.1
GPM6A
glycoprotein M6A
chr3_+_35721182 9.81 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_+_65730385 9.57 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_158787041 9.49 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr12_-_16762802 9.44 ENST00000534946.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_159557637 9.22 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr3_+_173116225 9.22 ENST00000457714.1
NLGN1
neuroligin 1
chr2_-_77749474 9.22 ENST00000409093.1
ENST00000409088.3
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr11_+_131240373 9.21 ENST00000374791.3
ENST00000436745.1
NTM
neurotrimin
chr3_+_111717511 8.94 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr5_-_160973649 8.89 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr12_-_16762971 8.87 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_-_77749446 8.83 ENST00000409911.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr11_-_83393429 8.72 ENST00000426717.2
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_86650045 8.71 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_+_111717600 8.65 ENST00000273368.4
TAGLN3
transgelin 3
chr11_-_126810521 8.57 ENST00000530572.1
RP11-688I9.4
RP11-688I9.4
chr11_-_8290263 8.53 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr13_-_36050819 8.48 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_+_41258786 8.47 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_50574585 8.46 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr8_+_77316233 8.42 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
RP11-706J10.3
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr13_+_36050881 8.27 ENST00000537702.1
NBEA
neurobeachin
chr5_+_173930676 8.24 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr4_-_176733897 8.22 ENST00000393658.2
GPM6A
glycoprotein M6A
chr12_-_87232644 8.20 ENST00000549405.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_210444298 8.20 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr5_+_174151536 8.19 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chrX_-_33357558 8.17 ENST00000288447.4
DMD
dystrophin
chrX_+_28605516 8.16 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr5_-_24645078 7.85 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr3_+_35721130 7.84 ENST00000432450.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr18_-_40857493 7.62 ENST00000255224.3
SYT4
synaptotagmin IV
chr17_-_10421853 7.60 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr18_-_3874271 7.59 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr10_+_24755416 7.41 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr18_-_53089723 7.37 ENST00000561992.1
ENST00000562512.2
TCF4
transcription factor 4
chr10_-_69455873 7.32 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr9_+_87286997 7.32 ENST00000395866.2
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr9_+_130026756 7.31 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr2_-_224467002 7.30 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr11_+_131240593 7.30 ENST00000539799.1
NTM
neurotrimin
chr5_+_161494521 7.29 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr1_+_170632250 7.27 ENST00000367760.3
PRRX1
paired related homeobox 1
chr18_+_32173276 7.23 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr1_-_102312517 7.22 ENST00000338858.5
OLFM3
olfactomedin 3
chr5_-_124084493 7.19 ENST00000509799.1
ZNF608
zinc finger protein 608
chr2_-_213403565 7.16 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr13_-_36429763 7.15 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr5_+_161494770 7.14 ENST00000414552.2
ENST00000361925.4
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_182850551 6.96 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr1_-_216896674 6.91 ENST00000475275.1
ENST00000469486.1
ENST00000481543.1
ESRRG
estrogen-related receptor gamma
chr16_+_7560114 6.88 ENST00000570626.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_84122033 6.85 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_+_123241908 6.85 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr2_+_166428839 6.84 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_+_210444142 6.81 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr18_+_59000815 6.80 ENST00000262717.4
CDH20
cadherin 20, type 2
chr12_+_79371565 6.74 ENST00000551304.1
SYT1
synaptotagmin I
chr8_+_80523321 6.71 ENST00000518111.1
STMN2
stathmin-like 2
chr3_+_111718036 6.62 ENST00000455401.2
TAGLN3
transgelin 3
chr2_-_175711133 6.59 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr2_+_210444748 6.59 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr12_-_99548645 6.54 ENST00000549025.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr18_-_24237339 6.52 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr12_+_41831485 6.49 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr7_+_114055052 6.45 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr12_-_86650077 6.41 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr13_-_103053946 6.35 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr12_-_16758873 6.29 ENST00000535535.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_12693336 6.27 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr8_+_79503458 6.25 ENST00000518467.1
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr19_+_30719410 6.19 ENST00000585628.1
ENST00000591488.1
ZNF536
zinc finger protein 536
chr9_-_13165457 6.13 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr12_-_16760021 6.10 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr2_+_47454054 6.05 ENST00000426892.1
AC106869.2
AC106869.2
chr11_-_83984231 5.88 ENST00000330014.6
ENST00000537455.1
ENST00000376106.3
ENST00000418306.2
ENST00000531015.1
DLG2
discs, large homolog 2 (Drosophila)
chr12_-_16758304 5.76 ENST00000320122.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_-_203055129 5.76 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr3_+_63428982 5.75 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr11_-_40315640 5.69 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr3_+_115342349 5.64 ENST00000393780.3
GAP43
growth associated protein 43
chr10_+_24528108 5.62 ENST00000438429.1
KIAA1217
KIAA1217
chr5_+_36606700 5.56 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_32073253 5.52 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr18_-_3845321 5.49 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr21_+_17442799 5.48 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_165414414 5.46 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr10_+_119302508 5.44 ENST00000442245.4
EMX2
empty spiracles homeobox 2
chr12_-_16758059 5.42 ENST00000261169.6
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_16758835 5.41 ENST00000541295.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr3_+_111718173 5.40 ENST00000494932.1
TAGLN3
transgelin 3
chr11_-_83393457 5.39 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr11_-_84634447 5.37 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr2_-_77749387 5.36 ENST00000409884.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr6_-_123958141 5.33 ENST00000334268.4
TRDN
triadin
chr7_-_14026123 5.32 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr2_-_77749336 5.24 ENST00000409282.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr11_-_84634217 5.20 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr8_-_42358742 5.18 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr4_+_88754113 5.16 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr4_+_114066764 5.15 ENST00000511380.1
ANK2
ankyrin 2, neuronal
chr1_+_107682629 5.12 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1
netrin G1
chr6_+_54173227 5.12 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chrX_+_135279179 5.08 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr3_+_35722844 5.03 ENST00000436702.1
ENST00000438071.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_-_80531399 5.01 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr5_-_1882858 5.01 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr2_+_210443993 4.97 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr5_-_41794313 4.86 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr4_-_87770416 4.86 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr12_-_117799446 4.85 ENST00000317775.6
ENST00000344089.3
NOS1
nitric oxide synthase 1 (neuronal)
chr2_-_152589670 4.82 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr16_-_29910853 4.81 ENST00000308713.5
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr3_+_69985734 4.79 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr2_+_36923901 4.78 ENST00000457137.2
VIT
vitrin
chr18_-_3874247 4.78 ENST00000581699.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chrX_+_135252050 4.74 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr8_+_104831472 4.72 ENST00000262231.10
ENST00000507740.1
RIMS2
regulating synaptic membrane exocytosis 2
chr10_-_21186144 4.67 ENST00000377119.1
NEBL
nebulette
chrX_+_135251783 4.64 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr13_-_67802549 4.58 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr5_-_96478466 4.55 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr12_+_81101277 4.54 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr7_-_107880508 4.54 ENST00000425651.2
NRCAM
neuronal cell adhesion molecule
chr1_-_102312600 4.51 ENST00000359814.3
OLFM3
olfactomedin 3
chr8_+_70476088 4.51 ENST00000525999.1
SULF1
sulfatase 1
chr3_+_35722487 4.49 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_46293378 4.48 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr8_-_40755333 4.47 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr5_-_38557561 4.47 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr7_-_81635106 4.43 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr18_-_3845293 4.41 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr9_+_77230499 4.41 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr12_-_86650154 4.40 ENST00000552435.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_76072719 4.38 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr4_+_41614909 4.37 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr4_+_88754069 4.37 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr2_-_180427304 4.37 ENST00000336917.5
ZNF385B
zinc finger protein 385B
chr6_-_56716686 4.35 ENST00000520645.1
DST
dystonin
chr16_-_14109841 4.34 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
CTD-2135D7.5
chr1_-_190446759 4.34 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr6_+_69942915 4.32 ENST00000604969.1
ENST00000603207.1
BAI3
brain-specific angiogenesis inhibitor 3
chr10_+_45406627 4.32 ENST00000389583.4
TMEM72
transmembrane protein 72
chr3_-_196911002 4.32 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr10_+_69869237 4.30 ENST00000373675.3
MYPN
myopalladin
chr22_-_36236623 4.30 ENST00000405409.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_142888573 4.29 ENST00000434794.1
LRP1B
low density lipoprotein receptor-related protein 1B
chr2_-_158182410 4.28 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr3_+_69985792 4.28 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chrM_+_9207 4.26 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr6_+_155537771 4.26 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_-_14026063 4.25 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr15_+_48051920 4.24 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_80531720 4.24 ENST00000416268.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr3_+_155838337 4.23 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr5_+_137203465 4.22 ENST00000239926.4
MYOT
myotilin
chr15_+_34260921 4.18 ENST00000560035.1
CHRM5
cholinergic receptor, muscarinic 5
chr18_-_21891460 4.18 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr4_-_186877806 4.18 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr4_-_87028478 4.18 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr1_-_91317072 4.17 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1
RP4-665J23.1
chr16_+_72459838 4.17 ENST00000564508.1
AC004158.3
AC004158.3
chr8_-_93107443 4.16 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_-_13835147 4.14 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr6_-_76203345 4.14 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr15_+_48498480 4.12 ENST00000380993.3
ENST00000396577.3
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr14_+_62462541 4.11 ENST00000430451.2
SYT16
synaptotagmin XVI
chr6_-_76203454 4.11 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr17_-_27333311 4.10 ENST00000317338.12
ENST00000585644.1
SEZ6
seizure related 6 homolog (mouse)
chr15_+_51669444 4.10 ENST00000396399.2
GLDN
gliomedin
chr2_+_170366203 4.09 ENST00000284669.1
KLHL41
kelch-like family member 41
chr9_+_103204553 4.09 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chrX_+_135251835 4.06 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr12_-_28124903 4.06 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH
parathyroid hormone-like hormone

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 112.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
4.8 33.8 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
4.8 14.4 GO:0048174 negative regulation of short-term neuronal synaptic plasticity(GO:0048174)
4.4 17.7 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
4.3 17.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
3.8 15.0 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
3.6 17.8 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
3.3 19.7 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.2 16.2 GO:0036371 protein localization to T-tubule(GO:0036371)
3.1 18.8 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
2.9 17.7 GO:0021764 amygdala development(GO:0021764)
2.9 8.8 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
2.9 25.8 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
2.7 8.2 GO:0007412 axon target recognition(GO:0007412)
2.7 8.2 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
2.5 15.2 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
2.4 7.2 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
2.3 7.0 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
1.9 24.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.8 41.5 GO:0071420 cellular response to histamine(GO:0071420)
1.8 12.3 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.7 5.2 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.7 6.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.6 14.6 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.4 5.8 GO:0098582 innate vocalization behavior(GO:0098582)
1.3 14.8 GO:0048664 neuron fate determination(GO:0048664)
1.3 7.9 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650)
1.3 6.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.3 16.8 GO:0002091 negative regulation of receptor internalization(GO:0002091)
1.3 17.9 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.3 17.9 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.3 3.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
1.2 54.2 GO:0097120 receptor localization to synapse(GO:0097120)
1.2 11.9 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.2 5.8 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
1.1 9.0 GO:0035995 detection of muscle stretch(GO:0035995)
1.1 7.5 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.1 13.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.0 8.3 GO:0003322 pancreatic A cell development(GO:0003322)
1.0 3.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.0 11.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
1.0 20.1 GO:0046069 cGMP catabolic process(GO:0046069)
1.0 7.9 GO:0072092 ureteric bud invasion(GO:0072092)
1.0 4.8 GO:0007525 somatic muscle development(GO:0007525)
0.9 7.6 GO:0046952 ketone body catabolic process(GO:0046952)
0.9 3.6 GO:0061348 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.9 7.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.9 7.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.9 2.7 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.9 8.8 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.9 5.2 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.9 9.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.8 3.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.8 2.5 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.8 3.4 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.8 2.5 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.8 8.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.8 4.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.8 2.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.8 9.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.8 7.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.8 11.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.8 8.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 3.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.8 3.8 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.8 9.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.7 14.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.7 2.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.7 1.4 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.7 4.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.7 3.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.7 7.4 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.7 10.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.6 1.9 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.6 2.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.6 50.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.6 3.8 GO:0018032 protein amidation(GO:0018032)
0.6 18.5 GO:0021542 dentate gyrus development(GO:0021542)
0.6 1.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.6 4.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.6 9.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.6 1.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.6 2.3 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.6 2.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.6 4.6 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 4.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.6 5.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.6 4.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.5 2.7 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.5 0.5 GO:1990709 presynaptic active zone organization(GO:1990709)
0.5 41.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.5 30.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.5 1.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.5 6.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 24.6 GO:0008038 neuron recognition(GO:0008038)
0.5 5.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 6.6 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.5 4.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.5 27.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.5 1.5 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.5 11.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.5 8.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.5 1.9 GO:0036269 swimming behavior(GO:0036269)
0.5 2.4 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.5 2.9 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.5 7.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.5 2.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.5 0.5 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.4 6.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 2.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.4 12.7 GO:0060074 synapse maturation(GO:0060074)
0.4 1.7 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.4 2.9 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.4 1.2 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.4 33.4 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 7.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.4 4.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.4 1.2 GO:0042245 RNA repair(GO:0042245)
0.4 29.3 GO:1901016 regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.4 3.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.4 9.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 3.8 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.4 8.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 2.6 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 4.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.4 5.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.4 1.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.4 2.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 1.4 GO:0033122 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.4 3.5 GO:0097338 response to clozapine(GO:0097338)
0.4 2.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 8.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.3 5.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 3.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.3 5.1 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.3 1.7 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.3 5.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 2.4 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.3 2.4 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.3 4.0 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 1.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 19.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 3.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.3 1.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 3.3 GO:0032596 protein transport into membrane raft(GO:0032596)
0.3 6.2 GO:0044557 relaxation of smooth muscle(GO:0044557)
0.3 1.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 8.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.3 3.2 GO:0021984 adenohypophysis development(GO:0021984)
0.3 1.9 GO:0036343 psychomotor behavior(GO:0036343) motor behavior(GO:0061744)
0.3 1.6 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 3.4 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.3 2.4 GO:0021681 cerebellar granular layer development(GO:0021681)
0.3 0.6 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.3 8.4 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.3 1.2 GO:0060529 ectoderm and mesoderm interaction(GO:0007499) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.3 5.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.3 4.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.3 63.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 6.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 15.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 1.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 4.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 1.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 1.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.3 1.5 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.3 2.3 GO:0072205 metanephric part of ureteric bud development(GO:0035502) metanephric collecting duct development(GO:0072205)
0.3 1.7 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 1.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.3 1.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 2.2 GO:0070459 prolactin secretion(GO:0070459)
0.3 0.8 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 2.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.3 6.2 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.3 0.3 GO:0097102 endothelial tip cell fate specification(GO:0097102)
0.3 1.6 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.3 1.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.3 1.8 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.3 2.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.3 2.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 1.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.2 12.9 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.2 4.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 1.0 GO:2000807 positive regulation of presynaptic membrane organization(GO:1901631) regulation of synaptic vesicle clustering(GO:2000807) positive regulation of synaptic vesicle clustering(GO:2000809)
0.2 2.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 1.7 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 2.8 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 3.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 5.1 GO:0003334 keratinocyte development(GO:0003334)
0.2 11.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.2 1.2 GO:0060005 vestibular reflex(GO:0060005)
0.2 8.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.9 GO:1903824 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 1.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 3.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 3.5 GO:0035640 exploration behavior(GO:0035640)
0.2 1.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.2 2.8 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.2 3.1 GO:0015705 iodide transport(GO:0015705)
0.2 3.8 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 6.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 0.8 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.2 1.9 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 6.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 35.5 GO:0048813 dendrite morphogenesis(GO:0048813)
0.2 2.2 GO:0001778 plasma membrane repair(GO:0001778)
0.2 1.8 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 1.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.4 GO:0051012 microtubule sliding(GO:0051012)
0.2 2.0 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.2 0.6 GO:0070375 ERK5 cascade(GO:0070375)
0.2 5.2 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.2 3.8 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.2 1.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 2.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.2 1.5 GO:0010669 epithelial structure maintenance(GO:0010669)
0.2 1.5 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.2 0.2 GO:0044851 anagen(GO:0042640) hair cycle phase(GO:0044851)
0.2 1.8 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 20.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.2 0.9 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 3.2 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.2 2.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 5.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.6 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.2 2.6 GO:0006527 arginine catabolic process(GO:0006527)
0.2 2.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.2 5.9 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 7.8 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.2 2.1 GO:0007635 chemosensory behavior(GO:0007635)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 3.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.8 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.2 0.8 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.2 0.6 GO:0035627 ceramide transport(GO:0035627)
0.2 0.8 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 2.5 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 4.7 GO:0010506 regulation of autophagy(GO:0010506)
0.1 0.6 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 2.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.9 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.4 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.1 0.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.9 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 2.4 GO:0006600 creatine metabolic process(GO:0006600)
0.1 1.6 GO:0005513 detection of calcium ion(GO:0005513)
0.1 10.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 1.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.5 GO:0034238 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 3.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 2.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.8 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 7.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.9 GO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential(GO:0098915)
0.1 0.9 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.5 GO:0090103 cochlea morphogenesis(GO:0090103)
0.1 5.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.8 GO:1904590 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.1 1.0 GO:0019236 response to pheromone(GO:0019236)
0.1 1.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 7.2 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 2.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 24.3 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.7 GO:0032528 microvillus organization(GO:0032528)
0.1 1.2 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 0.4 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 4.2 GO:0014047 glutamate secretion(GO:0014047)
0.1 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.4 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 4.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 2.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 1.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 2.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 1.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 2.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.1 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 3.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 0.7 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 4.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 3.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.0 GO:0007628 adult walking behavior(GO:0007628)
0.1 0.7 GO:0032916 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.1 1.8 GO:0051775 response to redox state(GO:0051775)
0.1 3.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 5.4 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.1 0.7 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.2 GO:0008306 associative learning(GO:0008306)
0.1 1.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 0.7 GO:0009214 cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214)
0.1 6.5 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 0.9 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.5 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.3 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.1 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 0.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.7 GO:0009629 response to gravity(GO:0009629)
0.1 0.3 GO:0060723 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 3.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.7 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.6 GO:0072217 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) negative regulation of metanephros development(GO:0072217)
0.1 1.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 4.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 3.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.4 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.1 1.2 GO:0015747 urate transport(GO:0015747)
0.1 8.1 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 22.0 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.1 22.1 GO:0006936 muscle contraction(GO:0006936)
0.1 0.3 GO:0051451 myoblast migration(GO:0051451)
0.1 1.7 GO:0030325 adrenal gland development(GO:0030325)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 2.3 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 4.5 GO:0015698 inorganic anion transport(GO:0015698)
0.1 1.8 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 2.0 GO:0050919 negative chemotaxis(GO:0050919)
0.1 12.4 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 0.8 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 1.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.7 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.4 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.1 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 1.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.8 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 9.2 GO:0008360 regulation of cell shape(GO:0008360)
0.1 0.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.3 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 1.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.2 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.1 1.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 5.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 21.3 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 4.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:1902307 positive regulation of sodium ion transmembrane transport(GO:1902307) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0034214 protein hexamerization(GO:0034214)
0.0 6.7 GO:0046718 viral entry into host cell(GO:0046718)
0.0 4.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 1.6 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 2.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 3.0 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.5 GO:0060065 uterus development(GO:0060065)
0.0 0.5 GO:0097205 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 2.8 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 2.0 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.7 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.4 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 1.0 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.1 GO:0097061 dendritic spine organization(GO:0097061)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 5.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 2.5 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 2.0 GO:0000910 cytokinesis(GO:0000910)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 1.2 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.7 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0015824 proline transport(GO:0015824)
0.0 0.6 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 2.8 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.1 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.8 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.6 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.8 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 1.1 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.5 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 1.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0060004 reflex(GO:0060004)
0.0 5.6 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 0.1 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.4 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.5 GO:0032210 regulation of telomere maintenance via telomerase(GO:0032210)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.8 GO:0006446 regulation of translational initiation(GO:0006446)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.4 GO:0032127 dense core granule membrane(GO:0032127)
2.9 31.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
2.2 19.7 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.7 20.5 GO:0016013 syntrophin complex(GO:0016013)
1.7 3.4 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
1.5 9.0 GO:0031673 H zone(GO:0031673)
1.4 22.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.3 6.5 GO:0032279 asymmetric synapse(GO:0032279)
1.2 3.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
1.2 47.6 GO:1902711 GABA-A receptor complex(GO:1902711)
1.2 7.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.2 21.9 GO:0033270 paranode region of axon(GO:0033270)
1.0 7.3 GO:0005916 fascia adherens(GO:0005916)
1.0 4.9 GO:1990425 ryanodine receptor complex(GO:1990425)
1.0 19.3 GO:0031045 dense core granule(GO:0031045)
0.9 41.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.9 11.5 GO:0043219 lateral loop(GO:0043219)
0.9 3.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.8 6.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.8 7.8 GO:0044305 calyx of Held(GO:0044305)
0.7 2.2 GO:0097444 spine apparatus(GO:0097444)
0.7 5.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.7 10.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 16.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.6 6.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.6 2.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.6 41.9 GO:0031430 M band(GO:0031430)
0.6 12.3 GO:0032982 myosin filament(GO:0032982)
0.6 8.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.6 1.7 GO:1990032 parallel fiber(GO:1990032)
0.5 2.2 GO:0072534 perineuronal net(GO:0072534)
0.5 13.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 14.7 GO:0043194 axon initial segment(GO:0043194)
0.5 3.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.5 9.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 3.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.5 3.6 GO:0070852 cell body fiber(GO:0070852)
0.5 30.3 GO:0042734 presynaptic membrane(GO:0042734)
0.5 9.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 3.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 25.5 GO:0048786 presynaptic active zone(GO:0048786)
0.5 7.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 4.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 170.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 13.8 GO:0005614 interstitial matrix(GO:0005614)
0.4 15.5 GO:0044295 axonal growth cone(GO:0044295)
0.4 8.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.4 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.4 4.3 GO:0032584 growth cone membrane(GO:0032584)
0.4 1.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.4 1.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.4 8.4 GO:0097440 apical dendrite(GO:0097440)
0.4 3.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.3 1.0 GO:0043257 laminin-8 complex(GO:0043257)
0.3 2.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 2.7 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.3 2.2 GO:0071438 invadopodium membrane(GO:0071438)
0.3 49.2 GO:0042383 sarcolemma(GO:0042383)
0.2 11.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 5.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.2 1.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 3.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.2 3.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.8 GO:0071439 clathrin complex(GO:0071439)
0.2 2.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 10.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 11.3 GO:0031594 neuromuscular junction(GO:0031594)
0.2 8.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 32.8 GO:0031674 I band(GO:0031674)
0.2 0.6 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 69.8 GO:0098794 postsynapse(GO:0098794)
0.2 65.7 GO:0005802 trans-Golgi network(GO:0005802)
0.2 0.8 GO:0043034 costamere(GO:0043034)
0.2 11.5 GO:0034707 chloride channel complex(GO:0034707)
0.2 11.9 GO:1904115 axon cytoplasm(GO:1904115)
0.2 6.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 2.5 GO:0043198 dendritic shaft(GO:0043198)
0.2 1.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 1.8 GO:0055028 cortical microtubule(GO:0055028)
0.2 1.9 GO:0071953 elastic fiber(GO:0071953)
0.2 1.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 8.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 30.4 GO:0031225 anchored component of membrane(GO:0031225)
0.2 22.5 GO:0030426 growth cone(GO:0030426)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.8 GO:0042025 host cell nucleus(GO:0042025)
0.1 1.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 9.1 GO:0043204 perikaryon(GO:0043204)
0.1 0.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 4.0 GO:0031984 organelle subcompartment(GO:0031984)
0.1 8.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 11.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 0.8 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.8 GO:0097422 tubular endosome(GO:0097422)
0.1 29.9 GO:0032993 protein-DNA complex(GO:0032993)
0.1 4.1 GO:0032420 stereocilium(GO:0032420)
0.1 3.1 GO:0071565 nBAF complex(GO:0071565)
0.1 2.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.4 GO:0031010 ISWI-type complex(GO:0031010)
0.1 21.9 GO:0043025 neuronal cell body(GO:0043025)
0.1 22.0 GO:0043209 myelin sheath(GO:0043209)
0.1 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 23.3 GO:0030424 axon(GO:0030424)
0.1 1.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0097451 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 1.0 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.9 GO:0097433 dense body(GO:0097433)
0.1 1.4 GO:0070469 respiratory chain(GO:0070469)
0.1 3.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 7.7 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 5.5 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0005922 connexon complex(GO:0005922)
0.1 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 2.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.3 GO:0005861 troponin complex(GO:0005861)
0.1 5.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 7.5 GO:0043005 neuron projection(GO:0043005)
0.0 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.9 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 27.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0030118 clathrin coat(GO:0030118)
0.0 3.3 GO:0045202 synapse(GO:0045202)
0.0 1.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 3.8 GO:0005770 late endosome(GO:0005770)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 9.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 10.4 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 10.1 GO:0030055 cell-substrate junction(GO:0030055)
0.0 1.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 26.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.5 GO:0000800 lateral element(GO:0000800)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0044297 cell body(GO:0044297)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 10.4 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 37.9 GO:0050682 AF-2 domain binding(GO:0050682)
3.1 34.0 GO:0030348 syntaxin-3 binding(GO:0030348)
2.9 26.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.9 20.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
2.6 7.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
2.5 15.2 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
2.1 8.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
2.1 8.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
1.9 7.6 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
1.8 26.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
1.7 13.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.6 9.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.5 25.8 GO:0097109 neuroligin family protein binding(GO:0097109)
1.5 4.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
1.5 32.1 GO:0003680 AT DNA binding(GO:0003680)
1.4 47.1 GO:0002162 dystroglycan binding(GO:0002162)
1.4 13.7 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
1.4 5.5 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
1.3 25.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.3 3.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
1.2 9.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
1.1 4.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
1.0 7.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
1.0 23.4 GO:0030215 semaphorin receptor binding(GO:0030215)
1.0 49.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.9 6.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.9 3.6 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.8 2.5 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.8 4.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.8 4.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.8 5.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.8 6.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.8 21.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.8 3.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.8 3.8 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.8 3.8 GO:0086056 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.7 7.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 3.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.7 12.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 5.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.7 2.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.6 3.8 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.6 7.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.6 8.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 5.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.6 19.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 19.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.6 8.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.5 3.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 13.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.5 7.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 29.2 GO:0070888 E-box binding(GO:0070888)
0.5 2.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 2.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 1.4 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.5 1.9 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 2.3 GO:0055100 adiponectin binding(GO:0055100)
0.5 4.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 1.8 GO:0017129 triglyceride binding(GO:0017129)
0.5 0.9 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.4 1.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.4 2.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 8.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.4 1.7 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4 14.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 1.3 GO:0034711 inhibin binding(GO:0034711)
0.4 20.2 GO:0017091 AU-rich element binding(GO:0017091)
0.4 0.8 GO:0046790 virion binding(GO:0046790)
0.4 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.4 1.2 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.4 2.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 2.8 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.4 1.2 GO:0019808 polyamine binding(GO:0019808)
0.4 3.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 9.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 1.5 GO:0031013 troponin I binding(GO:0031013)
0.4 2.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.4 2.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 2.9 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.4 24.3 GO:0030507 spectrin binding(GO:0030507)
0.4 66.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.4 12.2 GO:0005523 tropomyosin binding(GO:0005523)
0.4 7.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.4 1.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.4 2.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 4.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 4.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3 2.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.3 1.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.3 6.8 GO:0019966 interleukin-1 binding(GO:0019966)
0.3 2.4 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.3 3.4 GO:0004111 creatine kinase activity(GO:0004111)
0.3 1.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 2.7 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.3 2.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.3 4.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 7.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.3 6.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 7.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.3 0.9 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 11.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 3.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.3 2.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 41.1 GO:0030165 PDZ domain binding(GO:0030165)
0.3 3.0 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.3 1.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 9.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.3 0.6 GO:0030305 heparanase activity(GO:0030305)
0.3 14.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.3 3.2 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.3 5.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 15.4 GO:0042056 chemoattractant activity(GO:0042056)
0.3 1.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.3 0.8 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.3 1.7 GO:0071253 connexin binding(GO:0071253)
0.3 1.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.3 2.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.3 59.8 GO:0044325 ion channel binding(GO:0044325)
0.3 1.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 1.6 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.3 2.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.3 1.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 2.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 9.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 8.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 1.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.2 1.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.7 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 6.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 5.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.2 2.1 GO:0016594 glycine binding(GO:0016594)
0.2 0.9 GO:0098821 BMP receptor activity(GO:0098821)
0.2 1.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 4.7 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.9 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.2 1.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.2 2.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 59.9 GO:0005516 calmodulin binding(GO:0005516)
0.2 2.4 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.6 GO:0004359 glutaminase activity(GO:0004359)
0.2 2.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 5.5 GO:0050811 GABA receptor binding(GO:0050811)
0.2 5.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.1 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.2 4.7 GO:0030552 cAMP binding(GO:0030552)
0.2 8.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 6.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 47.3 GO:0051015 actin filament binding(GO:0051015)
0.2 2.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 5.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.2 12.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.2 1.1 GO:0045545 syndecan binding(GO:0045545)
0.2 1.7 GO:0008301 DNA binding, bending(GO:0008301)
0.2 19.2 GO:0005262 calcium channel activity(GO:0005262)
0.2 10.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 0.6 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.9 GO:0005534 galactose binding(GO:0005534)
0.1 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 7.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.9 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 2.6 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 3.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.5 GO:0035198 miRNA binding(GO:0035198)
0.1 13.9 GO:0002039 p53 binding(GO:0002039)
0.1 47.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.0 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 3.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.4 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 1.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.0 GO:0030553 cGMP binding(GO:0030553)
0.1 3.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 3.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 2.9 GO:0042393 histone binding(GO:0042393)
0.1 20.4 GO:0005057 receptor signaling protein activity(GO:0005057)
0.1 4.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.5 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 7.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.4 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 9.5 GO:0005254 chloride channel activity(GO:0005254)
0.1 3.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 10.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.1 GO:0042805 actinin binding(GO:0042805)
0.1 0.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.5 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 3.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.7 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 2.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 5.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 3.3 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.9 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.4 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 52.8 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.4 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0005542 folic acid binding(GO:0005542)
0.1 0.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol kinase activity(GO:0052742)
0.1 5.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.1 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 2.7 GO:0051117 ATPase binding(GO:0051117)
0.1 0.6 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 2.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.9 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 7.7 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 2.3 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 15.9 GO:0015631 tubulin binding(GO:0015631)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.7 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 11.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 10.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 1.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 7.9 GO:0042277 peptide binding(GO:0042277)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.2 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 10.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.1 GO:0002020 protease binding(GO:0002020)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.0 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0022839 ion gated channel activity(GO:0022839)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 4.9 GO:0003779 actin binding(GO:0003779)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0031072 heat shock protein binding(GO:0031072)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 49.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.4 27.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 13.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.3 25.1 PID LKB1 PATHWAY LKB1 signaling events
0.3 4.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 10.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 10.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 8.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 2.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.2 1.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 8.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 7.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 7.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.2 3.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 18.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 7.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 12.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.3 PID FGF PATHWAY FGF signaling pathway
0.1 5.4 PID REELIN PATHWAY Reelin signaling pathway
0.1 12.9 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 7.2 PID AURORA A PATHWAY Aurora A signaling
0.1 15.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 7.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 17.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 11.2 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 8.4 PID BMP PATHWAY BMP receptor signaling
0.1 3.4 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.9 ST GAQ PATHWAY G alpha q Pathway
0.1 2.5 PID CONE PATHWAY Visual signal transduction: Cones
0.1 5.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.5 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 2.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 5.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 21.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 5.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 4.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.9 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.4 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 15.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 2.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 50.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.2 28.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.9 29.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.8 68.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.7 18.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.6 16.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.6 28.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 25.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.4 10.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.4 8.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 16.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 14.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.3 22.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 34.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.3 4.9 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.3 4.5 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.3 7.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 6.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.3 8.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.3 7.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 2.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 4.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 16.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 4.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 15.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 9.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 6.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 4.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 2.4 REACTOME OPSINS Genes involved in Opsins
0.2 4.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.2 3.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 6.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.2 31.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 2.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 3.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 4.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 3.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 0.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.4 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 4.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 3.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.7 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.1 1.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 16.9 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 1.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 14.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 2.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes