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Illumina Body Map 2: averaged replicates
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Results for JDP2
Z-value: 1.55
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Transcription factors associated with JDP2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JDP2 | hg19_v2_chr14_+_75894714_75894749 | -0.20 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_97361388 Show fit | 3.78 |
ENST00000350485.4
ENST00000346867.4 |
tachykinin, precursor 1 |
|
| chr20_-_62129163 Show fit | 3.71 |
ENST00000298049.7
|
eukaryotic translation elongation factor 1 alpha 2 |
|
| chr7_+_97361218 Show fit | 3.32 |
ENST00000319273.5
|
tachykinin, precursor 1 |
|
| chr5_-_41794663 Show fit | 3.07 |
ENST00000510634.1
|
3-oxoacid CoA transferase 1 |
|
| chr5_-_41794313 Show fit | 2.68 |
ENST00000512084.1
|
3-oxoacid CoA transferase 1 |
|
| chr10_-_21463116 Show fit | 2.47 |
ENST00000417816.2
|
nebulette |
|
| chr9_+_34958254 Show fit | 2.43 |
ENST00000242315.3
|
KIAA1045 |
|
| chr2_-_175712479 Show fit | 2.42 |
ENST00000443238.1
|
chimerin 1 |
|
| chr2_-_175711978 Show fit | 2.42 |
ENST00000409089.2
|
chimerin 1 |
|
| chr9_+_34957477 Show fit | 2.42 |
ENST00000544237.1
|
KIAA1045 |
Network of associatons between targets according to the STRING database.
First level regulatory network of JDP2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.2 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 2.4 | 7.1 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 0.7 | 5.8 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 5.3 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 4.5 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.2 | 4.4 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 3.8 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.8 | 3.2 | GO:0035544 | negative regulation of SNARE complex assembly(GO:0035544) |
| 0.0 | 2.7 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 2.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.3 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.1 | 4.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 3.9 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.4 | 3.7 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.3 | 3.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 3.1 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.1 | 2.6 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.3 | 2.2 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 2.0 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 2.0 | GO:0036020 | endolysosome membrane(GO:0036020) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 1.4 | 5.8 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.1 | 5.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 4.8 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 4.1 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.4 | 3.7 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 3.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 2.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.1 | 2.7 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 2.6 | GO:0004385 | guanylate kinase activity(GO:0004385) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.1 | 2.0 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 2.0 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 1.8 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 1.1 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 1.0 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 5.3 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 5.1 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 4.6 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.0 | 3.7 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.0 | 2.7 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.0 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 2.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 1.9 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 1.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |