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Illumina Body Map 2: averaged replicates
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Results for JUN
Z-value: 2.78
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Transcription factors associated with JUN
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JUN | hg19_v2_chr1_-_59249732_59249785 | 0.30 | 9.8e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of JUN
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 34.0 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 17.5 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.1 | 12.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.3 | 12.0 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 9.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 9.3 | GO:0007286 | spermatid development(GO:0007286) |
| 1.7 | 8.6 | GO:0007343 | egg activation(GO:0007343) |
| 0.2 | 7.7 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 7.0 | GO:0042742 | defense response to bacterium(GO:0042742) |
| 0.4 | 6.4 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 21.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 4.9 | 14.7 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
| 0.1 | 13.6 | GO:0031514 | motile cilium(GO:0031514) |
| 0.6 | 12.0 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.1 | 11.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.8 | 11.0 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.3 | 10.8 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 10.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.5 | 8.5 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.6 | 7.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 34.0 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 18.7 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 14.5 | GO:0003779 | actin binding(GO:0003779) |
| 0.1 | 13.8 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 9.0 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 7.6 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 7.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 6.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 5.9 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 5.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 21.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 10.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 4.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 4.7 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 4.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 3.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 3.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 3.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 3.0 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 2.7 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.9 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.2 | 7.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 7.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 4.9 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 4.1 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 3.6 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 3.6 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 3.5 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 3.5 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 1.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |