ISMARA results: KLF15

Project

Illumina Body Map 2: averaged replicates

Navigation

Downloads

Results for KLF15

Z-value: 1.57

Motif logo

Transcription factors associated with KLF15

Gene Symbol	Gene ID	Gene Info
KLF15 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000163884.3	Kruppel like factor 15

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
KLF15	hg19_v2_chr3_-_126076264_126076305	-0.21	2.5e-01	Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_-_47407111 Show fit	2.54	ENST00000371904.4	CYP4A11 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_-_64410787 Show fit	2.53	ENST00000301894.2	NRXN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 2
chr20_-_22565101 Show fit	2.37	ENST00000419308.2	FOXA2 Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box A2
chr1_-_47407097 Show fit	2.37	ENST00000457840.2	CYP4A11 Ensembl NCBI GeneCards UniProt NextProt Show fit	cytochrome P450, family 4, subfamily A, polypeptide 11
chr7_+_29519486 Show fit	2.30	ENST00000409041.4	CHN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	chimerin 2
chr19_-_10047219 Show fit	2.11	ENST00000264833.4	OLFM2 Ensembl NCBI GeneCards UniProt NextProt Show fit	olfactomedin 2
chr19_+_55795493 Show fit	2.02	ENST00000309383.1	BRSK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	BR serine/threonine kinase 1
chrX_+_152907913 Show fit	2.01	ENST00000370167.4	DUSP9 Ensembl NCBI GeneCards UniProt NextProt Show fit	dual specificity phosphatase 9
chr14_-_65439132 Show fit	1.97	ENST00000533601.2	RAB15 Ensembl NCBI GeneCards UniProt NextProt Show fit	RAB15, member RAS oncogene family
chr16_+_23847339 Show fit	1.90	ENST00000303531.7	PRKCB Ensembl NCBI GeneCards UniProt NextProt Show fit	protein kinase C, beta

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	4.9	GO:0003095	pressure natriuresis(GO:0003095)
1.2	4.7	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
0.0	3.7	GO:1903307	positive regulation of regulated secretory pathway(GO:1903307)
0.1	3.6	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1	3.4	GO:0048627	myoblast development(GO:0048627)
1.1	3.2	GO:0002302	CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6	2.8	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1	2.6	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
0.3	2.5	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1	2.5	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)

Showing 1 to 10 of 176 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.0	GO:0043204	perikaryon(GO:0043204)
0.0	4.5	GO:0043202	lysosomal lumen(GO:0043202)
0.0	4.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	3.5	GO:0035580	specific granule lumen(GO:0035580)
0.0	3.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	2.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	2.1	GO:0097228	sperm principal piece(GO:0097228)
0.0	2.1	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.9	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.9	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Showing 1 to 10 of 60 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
1.0	4.9	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
1.2	4.7	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
0.0	3.4	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.2	3.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	2.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	2.5	GO:0097109	neuroligin family protein binding(GO:0097109)
0.2	2.4	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	2.4	GO:0008199	ferric iron binding(GO:0008199)
0.4	2.3	GO:0017153	citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)

Showing 1 to 10 of 113 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.7	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	4.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	4.2	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	3.9	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	3.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	3.4	PID BMP PATHWAY	BMP receptor signaling
0.0	2.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	2.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	2.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Showing 1 to 10 of 37 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.7	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	4.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	3.8	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	3.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	3.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	3.3	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	2.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	2.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	2.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	2.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters

Showing 1 to 10 of 48 entries

Results for KLF15

Z-value: 1.57

Motif logo

Transcription factors associated with KLF15

Activity-expression correlation:

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: