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Illumina Body Map 2: averaged replicates

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Results for LEF1

Z-value: 2.69

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Transcription factors associated with LEF1

Gene Symbol Gene ID Gene Info
ENSG00000138795.5 LEF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LEF1hg19_v2_chr4_-_109087906_109087953-0.467.8e-03Click!

Activity profile of LEF1 motif

Sorted Z-values of LEF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of LEF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_124553437 7.25 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr5_+_140480083 7.06 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr10_+_123970670 6.63 ENST00000496913.2
TACC2
transforming, acidic coiled-coil containing protein 2
chr11_-_111794446 6.09 ENST00000527950.1
CRYAB
crystallin, alpha B
chr7_-_27219849 5.96 ENST00000396344.4
HOXA10
homeobox A10
chr1_+_78383813 5.56 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr3_+_173302222 5.04 ENST00000361589.4
NLGN1
neuroligin 1
chr10_+_54074033 4.92 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr3_-_149375783 4.68 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr21_+_40823753 4.67 ENST00000333634.4
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr12_-_16759711 4.57 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_159141397 4.52 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr11_-_41481135 4.50 ENST00000528697.1
ENST00000530763.1
LRRC4C
leucine rich repeat containing 4C
chr9_-_97356075 4.50 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr21_+_40824003 4.49 ENST00000452550.1
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr6_-_127840453 4.33 ENST00000556132.1
SOGA3
SOGA family member 3
chr8_-_124665190 4.13 ENST00000325995.7
KLHL38
kelch-like family member 38
chr12_-_16760021 4.09 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_186877502 4.09 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_224467093 4.06 ENST00000305409.2
SCG2
secretogranin II
chr1_+_170633047 4.06 ENST00000239461.6
ENST00000497230.2
PRRX1
paired related homeobox 1
chr7_-_27224795 4.05 ENST00000006015.3
HOXA11
homeobox A11
chr5_-_146833485 3.98 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr15_+_63335899 3.94 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr15_+_96869165 3.94 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_27224842 3.94 ENST00000517402.1
HOXA11
homeobox A11
chr15_-_94614049 3.89 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr9_+_133971909 3.88 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L
allograft inflammatory factor 1-like
chr2_-_183387064 3.81 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr13_-_36429763 3.73 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr17_-_63557309 3.72 ENST00000580513.1
AXIN2
axin 2
chr15_+_43885252 3.71 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr15_+_43985725 3.69 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr5_-_146833803 3.68 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr7_+_70597109 3.65 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr12_-_16759440 3.59 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_-_27213893 3.59 ENST00000283921.4
HOXA10
homeobox A10
chr4_+_95972822 3.57 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_-_32173579 3.57 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chrX_-_15619076 3.52 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chrX_+_38420783 3.51 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr10_+_123923205 3.50 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr7_+_20370746 3.47 ENST00000222573.4
ITGB8
integrin, beta 8
chr20_+_36149602 3.43 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr3_+_2553281 3.42 ENST00000434053.1
CNTN4
contactin 4
chr2_+_176994408 3.40 ENST00000429017.1
ENST00000313173.4
ENST00000544999.1
HOXD8
homeobox D8
chr3_-_99569821 3.39 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr1_-_234667504 3.39 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr4_+_20255123 3.39 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr4_+_150999418 3.36 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr9_+_133971863 3.36 ENST00000372309.3
AIF1L
allograft inflammatory factor 1-like
chr7_+_20370300 3.34 ENST00000537992.1
ITGB8
integrin, beta 8
chr15_+_43985084 3.30 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr12_-_16761007 3.29 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_88449771 3.27 ENST00000535835.1
SPARCL1
SPARC-like 1 (hevin)
chr2_+_172950227 3.26 ENST00000341900.6
DLX1
distal-less homeobox 1
chr3_-_134093395 3.25 ENST00000249883.5
AMOTL2
angiomotin like 2
chr4_-_88450595 3.25 ENST00000434434.1
SPARCL1
SPARC-like 1 (hevin)
chr5_-_153857819 3.22 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr7_+_140774032 3.20 ENST00000565468.1
TMEM178B
transmembrane protein 178B
chr11_+_112832090 3.19 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chrX_-_138287168 3.16 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr3_+_29323043 3.12 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr13_-_110959478 3.11 ENST00000543140.1
ENST00000375820.4
COL4A1
collagen, type IV, alpha 1
chr11_-_47207390 3.10 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr1_+_100111479 3.09 ENST00000263174.4
PALMD
palmdelphin
chr6_-_105584560 3.08 ENST00000336775.5
BVES
blood vessel epicardial substance
chr2_-_224467002 3.07 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr2_-_175629164 3.07 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr14_-_23624511 3.05 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr8_+_80523321 3.04 ENST00000518111.1
STMN2
stathmin-like 2
chr1_+_100111580 3.00 ENST00000605497.1
PALMD
palmdelphin
chr18_+_32073253 2.98 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr12_-_6233828 2.97 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr3_+_132757215 2.96 ENST00000321871.6
ENST00000393130.3
ENST00000514894.1
ENST00000512662.1
TMEM108
transmembrane protein 108
chr8_-_21988558 2.96 ENST00000312841.8
HR
hair growth associated
chr7_+_30185406 2.95 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr5_+_131593364 2.92 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr10_+_73724123 2.90 ENST00000373115.4
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr2_-_183387430 2.87 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr11_-_8285405 2.86 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr7_-_80548493 2.82 ENST00000536800.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr12_+_53491220 2.81 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr5_-_44388899 2.81 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr7_+_73868439 2.78 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr18_-_24445729 2.77 ENST00000383168.4
AQP4
aquaporin 4
chr2_-_183387283 2.76 ENST00000435564.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr14_+_69726864 2.76 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr1_+_6845384 2.75 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr12_-_16762971 2.74 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_110009215 2.74 ENST00000369872.3
SYPL2
synaptophysin-like 2
chrX_-_128788914 2.74 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr8_-_22089845 2.73 ENST00000454243.2
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr14_-_61124977 2.71 ENST00000554986.1
SIX1
SIX homeobox 1
chr10_-_87551311 2.69 ENST00000536331.1
GRID1
glutamate receptor, ionotropic, delta 1
chrX_-_43832711 2.68 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr2_-_86564776 2.68 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr2_-_217560248 2.66 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr5_-_160973649 2.65 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr3_-_187388173 2.64 ENST00000287641.3
SST
somatostatin
chr20_-_42815733 2.62 ENST00000342272.3
JPH2
junctophilin 2
chr1_+_203096831 2.61 ENST00000337894.4
ADORA1
adenosine A1 receptor
chr6_-_112575912 2.60 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr2_+_220309379 2.59 ENST00000451076.1
SPEG
SPEG complex locus
chr15_-_93632421 2.59 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr2_-_175629135 2.59 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr7_+_73245193 2.56 ENST00000340958.2
CLDN4
claudin 4
chr12_+_7167980 2.56 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr2_-_72374948 2.54 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr19_-_18717627 2.54 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chrX_-_80457385 2.54 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr8_-_22089533 2.53 ENST00000321613.3
PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr14_+_69726968 2.51 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr3_-_58563094 2.51 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr3_-_134093275 2.51 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr11_+_112832202 2.50 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr11_-_118047376 2.47 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr14_-_21270995 2.45 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
RNASE1
ribonuclease, RNase A family, 1 (pancreatic)
chr6_+_138483058 2.43 ENST00000251691.4
KIAA1244
KIAA1244
chr2_-_152382500 2.43 ENST00000434685.1
NEB
nebulin
chr20_+_10199566 2.41 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr5_+_140797296 2.38 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr2_-_50574856 2.37 ENST00000342183.5
NRXN1
neurexin 1
chr8_-_17579726 2.36 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr16_+_6069586 2.36 ENST00000547372.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_198669365 2.35 ENST00000428675.1
PLCL1
phospholipase C-like 1
chr10_+_24497704 2.34 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr7_-_27239703 2.34 ENST00000222753.4
HOXA13
homeobox A13
chr15_+_80696666 2.34 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr21_+_35552978 2.33 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr17_-_63557759 2.33 ENST00000307078.5
AXIN2
axin 2
chr2_+_14772810 2.32 ENST00000295092.2
ENST00000331243.4
FAM84A
family with sequence similarity 84, member A
chr1_+_215256467 2.32 ENST00000391894.2
ENST00000444842.2
KCNK2
potassium channel, subfamily K, member 2
chr6_-_127840048 2.28 ENST00000467753.1
SOGA3
SOGA family member 3
chr6_+_69942915 2.22 ENST00000604969.1
ENST00000603207.1
BAI3
brain-specific angiogenesis inhibitor 3
chr18_-_53089538 2.22 ENST00000566777.1
TCF4
transcription factor 4
chr2_-_86564740 2.21 ENST00000540790.1
ENST00000428491.1
REEP1
receptor accessory protein 1
chr2_-_72375167 2.21 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr4_+_114214125 2.20 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr15_-_41120896 2.19 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr8_+_85095769 2.18 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr20_+_10199468 2.18 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr3_-_66024213 2.17 ENST00000483466.1
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr10_+_24498060 2.17 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr12_-_22063787 2.16 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chrX_+_135229559 2.15 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr9_+_124088860 2.14 ENST00000373806.1
GSN
gelsolin
chr9_-_91793675 2.14 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr10_-_116164239 2.12 ENST00000419268.1
ENST00000304129.4
ENST00000545353.1
AFAP1L2
actin filament associated protein 1-like 2
chr5_+_140864649 2.12 ENST00000306593.1
PCDHGC4
protocadherin gamma subfamily C, 4
chr8_-_119964434 2.12 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr7_-_80548667 2.12 ENST00000265361.3
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr10_-_61900762 2.11 ENST00000355288.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr18_-_24445664 2.09 ENST00000578776.1
AQP4
aquaporin 4
chr1_+_6845578 2.09 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr12_-_16761117 2.09 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_+_101962128 2.09 ENST00000550514.1
MYBPC1
myosin binding protein C, slow type
chr11_+_113930955 2.08 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr9_-_23825956 2.08 ENST00000397312.2
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr18_-_31802056 2.07 ENST00000538587.1
NOL4
nucleolar protein 4
chr11_-_119234876 2.06 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chrX_+_135229600 2.06 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr3_+_259218 2.05 ENST00000449294.2
CHL1
cell adhesion molecule L1-like
chr4_-_5891918 2.05 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr4_-_20985632 2.05 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr16_+_6069072 2.04 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_+_15341442 2.03 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chrX_+_46937745 2.03 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
RGN
regucalcin
chr11_+_101983176 2.03 ENST00000524575.1
YAP1
Yes-associated protein 1
chr2_+_18059906 2.01 ENST00000304101.4
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr11_+_112832133 2.00 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr14_+_85996471 2.00 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr7_+_30185496 1.99 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr20_+_57875457 1.99 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr21_+_19617140 1.97 ENST00000299295.2
ENST00000338326.3
CHODL
chondrolectin
chr3_+_29322437 1.97 ENST00000434693.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr18_-_31802282 1.97 ENST00000535475.1
NOL4
nucleolar protein 4
chr9_+_101705893 1.97 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr5_+_175288631 1.96 ENST00000509837.1
CPLX2
complexin 2
chr1_+_170632250 1.96 ENST00000367760.3
PRRX1
paired related homeobox 1
chr19_+_13135439 1.96 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_30719410 1.96 ENST00000585628.1
ENST00000591488.1
ZNF536
zinc finger protein 536
chr1_+_82266053 1.93 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr14_+_24837226 1.92 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr4_-_5894777 1.92 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr2_-_161056802 1.92 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr7_-_27219632 1.91 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr17_+_27920486 1.91 ENST00000394859.3
ANKRD13B
ankyrin repeat domain 13B
chr2_+_155555201 1.91 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr16_-_4987065 1.90 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr10_-_116164450 1.89 ENST00000369271.3
AFAP1L2
actin filament associated protein 1-like 2
chr1_+_215179188 1.88 ENST00000391895.2
KCNK2
potassium channel, subfamily K, member 2
chr14_+_85996507 1.88 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr12_-_130529501 1.87 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
chr11_-_125351481 1.86 ENST00000577924.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr3_+_189349162 1.83 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr11_-_104769141 1.83 ENST00000508062.1
ENST00000422698.2
CASP12
caspase 12 (gene/pseudogene)
chr6_-_127840021 1.82 ENST00000465909.2
SOGA3
SOGA family member 3
chr20_+_30598231 1.82 ENST00000300415.8
ENST00000262659.8
CCM2L
cerebral cavernous malformation 2-like
chr11_-_47206965 1.82 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.6 GO:0061181 regulation of chondrocyte development(GO:0061181)
1.9 5.6 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.6 4.9 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
1.6 4.8 GO:2001035 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
1.5 20.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
1.4 5.5 GO:0009956 radial pattern formation(GO:0009956)
1.3 6.3 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
1.3 5.0 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
1.1 4.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
1.1 4.5 GO:0005986 sucrose biosynthetic process(GO:0005986)
1.1 3.3 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
1.1 2.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
1.1 3.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.0 3.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.0 3.1 GO:0060931 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.9 2.8 GO:0071338 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) secretion by lung epithelial cell involved in lung growth(GO:0061033) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.9 6.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.9 2.7 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.9 4.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.9 2.7 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.9 1.8 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.9 2.6 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.8 4.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.8 4.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.8 3.2 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.8 1.6 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.8 3.1 GO:0060901 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.8 3.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.8 3.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.7 2.1 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.7 3.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.7 2.7 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.7 2.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.7 2.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.7 3.3 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.6 3.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 4.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.6 5.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.6 1.8 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.6 5.9 GO:0048664 neuron fate determination(GO:0048664)
0.6 11.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.5 3.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.5 1.5 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.5 2.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.5 21.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.5 3.9 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.5 0.9 GO:0060197 cloacal septation(GO:0060197)
0.5 1.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 4.9 GO:0003350 pulmonary myocardium development(GO:0003350)
0.4 2.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.4 0.4 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.4 2.1 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4 2.1 GO:0007525 somatic muscle development(GO:0007525)
0.4 5.3 GO:0097106 postsynaptic density organization(GO:0097106)
0.4 7.0 GO:0006600 creatine metabolic process(GO:0006600)
0.4 1.6 GO:0036269 swimming behavior(GO:0036269)
0.4 1.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.4 5.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.4 1.9 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.4 7.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.4 1.8 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582) regulation of neuromuscular junction development(GO:1904396)
0.4 8.4 GO:0071420 cellular response to histamine(GO:0071420)
0.4 2.5 GO:0046684 response to pyrethroid(GO:0046684)
0.4 2.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 1.1 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 1.4 GO:0060166 olfactory pit development(GO:0060166)
0.3 1.4 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.3 6.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 1.0 GO:1903800 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 2.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 12.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.3 3.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 0.6 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.3 3.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.3 1.2 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.3 7.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.3 2.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.3 6.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.3 5.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 7.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 2.4 GO:0003383 apical constriction(GO:0003383)
0.3 3.4 GO:0009249 protein lipoylation(GO:0009249)
0.3 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 2.6 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.3 2.9 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 3.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 1.0 GO:0044691 tooth eruption(GO:0044691)
0.3 1.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 6.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 1.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 1.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.2 1.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 11.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.8 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.2 0.6 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 3.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 2.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 1.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.7 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.2 1.0 GO:0035633 maintenance of blood-brain barrier(GO:0035633) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 1.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.2 0.5 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.2 2.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 0.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.2 0.5 GO:0061056 sclerotome development(GO:0061056)
0.2 0.8 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 1.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 0.8 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 6.7 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 8.9 GO:0035329 hippo signaling(GO:0035329)
0.1 5.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.6 GO:0070293 renal sodium ion transport(GO:0003096) renal absorption(GO:0070293) renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.1 2.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 2.1 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.6 GO:0001778 plasma membrane repair(GO:0001778)
0.1 1.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 4.9 GO:0006833 water transport(GO:0006833)
0.1 0.5 GO:0060462 lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1 1.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.6 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.6 GO:0050893 sensory processing(GO:0050893)
0.1 1.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 2.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.5 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 3.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 2.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 1.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 6.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 5.1 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.3 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 1.4 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.7 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 1.8 GO:0097264 self proteolysis(GO:0097264)
0.1 1.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.6 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 3.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 1.8 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.3 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 3.2 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 2.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 3.0 GO:0015695 organic cation transport(GO:0015695)
0.1 1.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 1.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.1 15.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.8 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1 3.4 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 4.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 2.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 4.0 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.1 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 1.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 0.9 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.3 GO:0080154 regulation of fertilization(GO:0080154)
0.1 4.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.1 5.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.9 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 1.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 3.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 8.4 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.4 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.3 GO:0070980 biphenyl catabolic process(GO:0070980)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 1.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 2.8 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 3.0 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 8.0 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 3.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.9 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 2.4 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.8 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 1.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.8 GO:0019532 oxalate transport(GO:0019532)
0.0 8.2 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 1.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 2.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 2.7 GO:0021762 substantia nigra development(GO:0021762)
0.0 2.4 GO:0008542 visual learning(GO:0008542)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.9 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.7 GO:0007567 parturition(GO:0007567)
0.0 0.8 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.3 GO:0031103 axon regeneration(GO:0031103)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.1 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 1.7 GO:0060047 heart contraction(GO:0060047)
0.0 1.0 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.0 0.8 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.0 GO:0014047 glutamate secretion(GO:0014047)
0.0 2.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.8 GO:0097502 mannosylation(GO:0097502)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 2.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.8 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151) phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.0 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.8 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.6 3.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.7 3.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.6 4.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.5 2.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.5 5.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.5 5.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.4 4.2 GO:0044305 calyx of Held(GO:0044305)
0.4 6.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 6.1 GO:0097512 cardiac myofibril(GO:0097512)
0.3 3.6 GO:0016013 syntrophin complex(GO:0016013)
0.3 2.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.3 8.6 GO:0031045 dense core granule(GO:0031045)
0.3 1.6 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 6.7 GO:0032433 filopodium tip(GO:0032433)
0.3 6.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 6.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 1.8 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.2 5.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 2.6 GO:0030314 junctional membrane complex(GO:0030314)
0.2 0.6 GO:0005584 collagen type I trimer(GO:0005584)
0.2 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.2 GO:0031673 H zone(GO:0031673)
0.2 3.8 GO:0032059 bleb(GO:0032059)
0.2 1.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 10.7 GO:0031941 filamentous actin(GO:0031941)
0.2 6.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.2 6.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.2 3.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 39.3 GO:0030018 Z disc(GO:0030018)
0.2 2.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 2.1 GO:0030478 actin cap(GO:0030478)
0.1 2.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 5.7 GO:0005605 basal lamina(GO:0005605)
0.1 9.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.2 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 1.1 GO:0034464 BBSome(GO:0034464)
0.1 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.6 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 2.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 9.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 7.8 GO:0005884 actin filament(GO:0005884)
0.1 2.1 GO:0005685 U1 snRNP(GO:0005685)
0.1 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 3.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 9.7 GO:0043296 apical junction complex(GO:0043296)
0.1 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 8.2 GO:0043197 dendritic spine(GO:0043197)
0.1 3.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 17.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 28.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 11.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 4.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 4.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 2.8 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 9.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 6.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 3.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.0 GO:0005921 gap junction(GO:0005921)
0.0 6.3 GO:0030424 axon(GO:0030424)
0.0 1.7 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 4.2 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0044297 cell body(GO:0044297)
0.0 0.4 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 11.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
1.1 6.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.1 4.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
1.1 3.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.9 6.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.8 4.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.8 3.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.7 3.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 7.0 GO:0004111 creatine kinase activity(GO:0004111)
0.7 4.8 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.6 7.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 2.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.5 6.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 2.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.4 3.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.4 1.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.4 1.2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.4 5.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 6.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.4 3.4 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.4 2.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.4 2.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 3.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 2.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 2.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 1.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 1.6 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 6.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 3.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 4.4 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.3 2.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 2.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 1.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 4.9 GO:0015250 water channel activity(GO:0015250)
0.3 1.0 GO:1990175 EH domain binding(GO:1990175)
0.3 3.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 2.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 6.5 GO:0031005 filamin binding(GO:0031005)
0.2 3.2 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2 7.8 GO:0071837 HMG box domain binding(GO:0071837)
0.2 1.1 GO:0070052 collagen V binding(GO:0070052)
0.2 5.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 5.9 GO:0070411 I-SMAD binding(GO:0070411)
0.2 6.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 25.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.0 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 3.9 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.8 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.7 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.2 4.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 1.0 GO:0070905 serine binding(GO:0070905)
0.2 2.1 GO:0045159 myosin II binding(GO:0045159)
0.2 1.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 4.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 4.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 2.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 5.8 GO:0001972 retinoic acid binding(GO:0001972)
0.2 2.0 GO:0019534 toxin transporter activity(GO:0019534)
0.2 1.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 6.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 2.3 GO:0019871 potassium channel inhibitor activity(GO:0019870) sodium channel inhibitor activity(GO:0019871)
0.1 5.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.6 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 2.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.4 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 2.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.1 GO:0045118 azole transporter activity(GO:0045118)
0.1 2.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.0 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 2.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 5.7 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 3.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 2.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 11.4 GO:0001618 virus receptor activity(GO:0001618)
0.1 0.4 GO:0098960 postsynaptic neurotransmitter receptor activity(GO:0098960)
0.1 2.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 4.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.0 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 2.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.9 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.1 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 4.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 2.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 12.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 1.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 7.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 4.3 GO:0030507 spectrin binding(GO:0030507)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 2.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.8 GO:0019841 retinol binding(GO:0019841)
0.1 7.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 4.9 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.8 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 2.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 4.4 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 3.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 6.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 2.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.8 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 4.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 6.2 GO:0051015 actin filament binding(GO:0051015)
0.0 2.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 10.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.4 GO:0017022 myosin binding(GO:0017022)
0.0 4.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.1 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 2.3 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.9 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.7 PID FGF PATHWAY FGF signaling pathway
0.2 8.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 6.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 6.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 8.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 9.0 PID BMP PATHWAY BMP receptor signaling
0.1 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 2.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 4.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 20.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 3.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID ARF 3PATHWAY Arf1 pathway
0.0 3.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 6.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 2.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 PID FOXO PATHWAY FoxO family signaling
0.0 1.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 18.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 15.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 4.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 5.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 12.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 8.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.2 5.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 3.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 4.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 6.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 5.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.5 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 11.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 11.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 5.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 5.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.9 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 4.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 4.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 1.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.3 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 3.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 4.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 3.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 7.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 8.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.8 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins