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Illumina Body Map 2: averaged replicates

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Results for LHX6

Z-value: 1.31

Motif logo

Transcription factors associated with LHX6

Gene Symbol Gene ID Gene Info
ENSG00000106852.11 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX6hg19_v2_chr9_-_124976154_1249761770.115.5e-01Click!

Activity profile of LHX6 motif

Sorted Z-values of LHX6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_37723336 1.64 ENST00000450180.1
G protein-coupled receptor 141
chr6_-_62996066 1.41 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr15_+_51669513 1.38 ENST00000558426.1
gliomedin
chr11_-_102651343 1.34 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr5_-_35938674 1.33 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr12_+_8666126 1.32 ENST00000299665.2
C-type lectin domain family 4, member D
chr12_-_45269251 1.21 ENST00000553120.1
NEL-like 2 (chicken)
chr12_-_45269430 1.16 ENST00000395487.2
NEL-like 2 (chicken)
chr16_-_55866997 1.07 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr21_-_22175341 1.07 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
long intergenic non-protein coding RNA 320
chr18_+_61143994 0.97 ENST00000382771.4
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr6_+_30457244 0.96 ENST00000376630.4
major histocompatibility complex, class I, E
chr12_-_45270077 0.94 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NEL-like 2 (chicken)
chr17_+_11757333 0.94 ENST00000579703.1
dynein, axonemal, heavy chain 9
chr9_-_71161505 0.94 ENST00000446290.1
RP11-274B18.2
chr9_-_38424443 0.92 ENST00000377694.1
insulin-like growth factor binding protein-like 1
chr1_-_21620877 0.89 ENST00000527991.1
endothelin converting enzyme 1
chr6_-_167040693 0.89 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_772901 0.88 ENST00000305108.4
ninjurin 2
chr12_-_45270151 0.87 ENST00000429094.2
NEL-like 2 (chicken)
chr14_+_60386853 0.87 ENST00000570145.1
leucine rich repeat containing 9
chr18_-_44181442 0.82 ENST00000398722.4
lipoxygenase homology domains 1
chr18_-_67624160 0.82 ENST00000581982.1
ENST00000280200.4
CD226 molecule
chr7_-_14029515 0.78 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr17_-_73937028 0.78 ENST00000586631.2
Fas (TNFRSF6) binding factor 1
chr7_-_36764142 0.78 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr9_+_1050331 0.76 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
doublesex and mab-3 related transcription factor 2
chr12_-_45269769 0.76 ENST00000548826.1
NEL-like 2 (chicken)
chr5_-_171881362 0.73 ENST00000519643.1
SH3 and PX domains 2B
chr10_+_71562180 0.72 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr19_+_29374337 0.72 ENST00000591285.1
AC011524.1
chr2_+_90043607 0.72 ENST00000462693.1
immunoglobulin kappa variable 2D-24 (non-functional)
chr10_+_71561630 0.70 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr10_+_71561649 0.70 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr19_-_42916499 0.70 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr5_-_82969405 0.68 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr4_+_71296204 0.68 ENST00000413702.1
mucin 7, secreted
chr5_+_142149932 0.68 ENST00000274498.4
Rho GTPase activating protein 26
chr7_-_111424506 0.68 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr7_+_37723450 0.68 ENST00000447769.1
G protein-coupled receptor 141
chr21_-_43916433 0.67 ENST00000291536.3
radial spoke head 1 homolog (Chlamydomonas)
chr6_+_122931366 0.67 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr17_-_62208169 0.65 ENST00000606895.1
endoplasmic reticulum to nucleus signaling 1
chr19_-_14889349 0.65 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
egf-like module containing, mucin-like, hormone receptor-like 2
chr15_-_64673630 0.64 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr19_-_52307357 0.63 ENST00000594900.1
formyl peptide receptor 1
chr9_+_12695702 0.63 ENST00000381136.2
tyrosinase-related protein 1
chr12_+_16500599 0.62 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr3_+_85008089 0.62 ENST00000383699.3
cell adhesion molecule 2
chr6_-_167040731 0.62 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_-_89476644 0.61 ENST00000484817.1
immunoglobulin kappa variable 2-24
chr7_-_64467031 0.61 ENST00000394323.2
endogenous retrovirus group 3, member 1
chr11_-_118023594 0.61 ENST00000529878.1
sodium channel, voltage-gated, type IV, beta subunit
chr13_+_37006421 0.61 ENST00000255465.4
cyclin A1
chr10_+_103986085 0.60 ENST00000370005.3
ELOVL fatty acid elongase 3
chr14_-_100842588 0.60 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
tryptophanyl-tRNA synthetase
chr6_+_148663729 0.60 ENST00000367467.3
SAM and SH3 domain containing 1
chr21_-_43916296 0.60 ENST00000398352.3
radial spoke head 1 homolog (Chlamydomonas)
chr20_+_19867150 0.59 ENST00000255006.6
Ras and Rab interactor 2
chr6_+_148593425 0.59 ENST00000367469.1
SAM and SH3 domain containing 1
chr7_+_70597109 0.59 ENST00000333538.5
Williams-Beuren syndrome chromosome region 17
chr13_+_37005967 0.58 ENST00000440264.1
ENST00000449823.1
cyclin A1
chr4_-_174255400 0.58 ENST00000506267.1
high mobility group box 2
chr4_+_144312659 0.58 ENST00000509992.1
GRB2-associated binding protein 1
chr4_-_103749205 0.58 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr3_+_130162328 0.57 ENST00000512482.1
collagen, type VI, alpha 5
chr12_-_91546926 0.56 ENST00000550758.1
decorin
chrX_+_37639302 0.56 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr7_-_36764062 0.55 ENST00000435386.1
acyloxyacyl hydrolase (neutrophil)
chr3_-_157221128 0.55 ENST00000392833.2
ENST00000362010.2
ventricular zone expressed PH domain-containing 1
chr16_-_55867146 0.54 ENST00000422046.2
carboxylesterase 1
chr5_+_66300464 0.54 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr11_-_35287243 0.53 ENST00000464522.2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_-_232598163 0.53 ENST00000308942.4
signal-induced proliferation-associated 1 like 2
chr7_-_111424462 0.52 ENST00000437129.1
dedicator of cytokinesis 4
chr4_+_158493642 0.52 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr3_-_149095652 0.52 ENST00000305366.3
transmembrane 4 L six family member 1
chr4_+_144354644 0.51 ENST00000512843.1
GRB2-associated binding protein 1
chr18_-_67624412 0.49 ENST00000580335.1
CD226 molecule
chr13_+_37006398 0.49 ENST00000418263.1
cyclin A1
chr2_-_152118276 0.49 ENST00000409092.1
RNA binding motif protein 43
chr18_+_60190682 0.49 ENST00000588676.1
zinc finger, CCHC domain containing 2
chr12_-_9760482 0.48 ENST00000229402.3
killer cell lectin-like receptor subfamily B, member 1
chr12_+_7014126 0.48 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr12_+_16500037 0.48 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr11_-_102668879 0.47 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr4_-_174255536 0.46 ENST00000446922.2
high mobility group box 2
chr8_-_13134045 0.46 ENST00000512044.2
deleted in liver cancer 1
chr18_+_44526744 0.45 ENST00000585469.1
katanin p60 subunit A-like 2
chr19_+_12902289 0.45 ENST00000302754.4
jun B proto-oncogene
chr1_+_40713573 0.45 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr5_+_66300446 0.45 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr6_+_29691198 0.44 ENST00000440587.2
ENST00000434407.2
major histocompatibility complex, class I, F
chr11_+_59856130 0.44 ENST00000278888.3
membrane-spanning 4-domains, subfamily A, member 2
chr11_+_76156045 0.43 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chr12_+_16500571 0.42 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr15_-_77712477 0.42 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr1_-_204380919 0.41 ENST00000367188.4
protein phosphatase 1, regulatory subunit 15B
chr3_-_157221380 0.41 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr5_-_110848189 0.41 ENST00000296632.3
ENST00000512160.1
ENST00000509887.1
StAR-related lipid transfer (START) domain containing 4
chr11_-_76155700 0.40 ENST00000572035.1
RP11-111M22.3
chr5_+_142149955 0.40 ENST00000378004.3
Rho GTPase activating protein 26
chr18_-_67623906 0.40 ENST00000583955.1
CD226 molecule
chr1_-_48866517 0.39 ENST00000371841.1
spermatogenesis associated 6
chr16_+_31885079 0.39 ENST00000300870.10
ENST00000394846.3
zinc finger protein 267
chr19_-_10121144 0.39 ENST00000264828.3
collagen, type V, alpha 3
chr3_-_157221357 0.39 ENST00000494677.1
ventricular zone expressed PH domain-containing 1
chr7_-_151330218 0.39 ENST00000476632.1
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr10_+_71561704 0.39 ENST00000520267.1
collagen, type XIII, alpha 1
chr2_-_192711968 0.38 ENST00000304141.4
serum deprivation response
chr15_-_77712429 0.38 ENST00000564328.1
ENST00000558305.1
pseudopodium-enriched atypical kinase 1
chr11_-_33913708 0.38 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr9_+_12775011 0.38 ENST00000319264.3
leucine rich adaptor protein 1-like
chr17_+_66511540 0.38 ENST00000588188.2
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr19_-_12833361 0.37 ENST00000592287.1
transportin 2
chr7_+_21582638 0.37 ENST00000409508.3
ENST00000328843.6
dynein, axonemal, heavy chain 11
chr2_+_29341037 0.37 ENST00000449202.1
CAP-GLY domain containing linker protein family, member 4
chr5_-_110848253 0.37 ENST00000505803.1
ENST00000502322.1
StAR-related lipid transfer (START) domain containing 4
chr12_-_53045948 0.37 ENST00000309680.3
keratin 2
chr6_+_29691056 0.36 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
major histocompatibility complex, class I, F
chr2_-_55276320 0.36 ENST00000357376.3
reticulon 4
chr6_+_34204642 0.36 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr1_-_152386732 0.35 ENST00000271835.3
cornulin
chr2_+_65454926 0.35 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr18_+_616672 0.35 ENST00000338387.7
clusterin-like 1 (retinal)
chr15_+_77713222 0.35 ENST00000558176.1
high mobility group 20A
chr16_-_66583994 0.35 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr6_-_27880174 0.34 ENST00000303324.2
olfactory receptor, family 2, subfamily B, member 2
chr12_+_7014064 0.34 ENST00000443597.2
leucine rich repeat containing 23
chrY_+_14813160 0.33 ENST00000338981.3
ubiquitin specific peptidase 9, Y-linked
chr6_-_138833630 0.33 ENST00000533765.1
NHS-like 1
chr3_-_112693759 0.33 ENST00000440122.2
ENST00000490004.1
CD200 receptor 1
chr13_+_24825824 0.33 ENST00000434675.1
ENST00000494772.1
spermatogenesis associated 13
chr17_+_74261413 0.32 ENST00000587913.1
UBA-like domain containing 2
chr7_-_86849836 0.31 ENST00000455575.1
transmembrane protein 243, mitochondrial
chr6_-_49681235 0.31 ENST00000339139.4
cysteine-rich secretory protein 2
chr2_-_74618907 0.31 ENST00000421392.1
ENST00000437375.1
dynactin 1
chrX_+_113818545 0.31 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr21_-_22175450 0.30 ENST00000435279.2
long intergenic non-protein coding RNA 320
chr2_-_201936302 0.30 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr12_+_7013897 0.30 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr5_+_115358088 0.29 ENST00000600981.3
CTD-2287O16.3
chr19_-_12833164 0.29 ENST00000356861.5
transportin 2
chr2_-_101925055 0.29 ENST00000295317.3
ring finger protein 149
chr4_-_66536196 0.29 ENST00000511294.1
EPH receptor A5
chr14_+_57671888 0.29 ENST00000391612.1
AL391152.1
chr20_+_30467600 0.29 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr3_+_172468472 0.28 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr19_+_41869894 0.28 ENST00000413014.2
transmembrane protein 91
chr2_+_65454863 0.28 ENST00000260641.5
ARP2 actin-related protein 2 homolog (yeast)
chr8_+_42010464 0.28 ENST00000518421.1
ENST00000174653.3
ENST00000396926.3
ENST00000521280.1
ENST00000522288.1
adaptor-related protein complex 3, mu 2 subunit
chr12_+_66696322 0.27 ENST00000247815.4
helicase (DNA) B
chr16_-_66584059 0.27 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chrX_-_24690771 0.27 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr6_+_26402517 0.27 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr12_+_21654714 0.26 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr17_+_59489112 0.26 ENST00000335108.2
chromosome 17 open reading frame 82
chr11_-_102714534 0.26 ENST00000299855.5
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_42906965 0.26 ENST00000586267.1
gap junction protein, gamma 1, 45kDa
chr11_-_76155618 0.25 ENST00000530759.1
RP11-111M22.3
chr1_+_81771806 0.25 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
latrophilin 2
chr15_-_64673665 0.25 ENST00000300035.4
KIAA0101
chr4_-_103749179 0.25 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr12_-_110883346 0.25 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr2_+_113763031 0.25 ENST00000259211.6
interleukin 36, alpha
chr6_+_26402465 0.25 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chr17_-_38210644 0.24 ENST00000394128.2
ENST00000394127.2
ENST00000356271.3
ENST00000535071.2
ENST00000580885.1
ENST00000543759.2
ENST00000537674.2
ENST00000580517.1
ENST00000578161.1
mediator complex subunit 24
chr13_+_98086445 0.24 ENST00000245304.4
RAP2A, member of RAS oncogene family
chr9_+_71944241 0.24 ENST00000257515.8
family with sequence similarity 189, member A2
chr4_-_46126093 0.24 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr4_-_121843985 0.24 ENST00000264808.3
ENST00000428209.2
ENST00000515109.1
ENST00000394435.2
PR domain containing 5
chrX_-_47509994 0.24 ENST00000343894.4
ELK1, member of ETS oncogene family
chr12_+_64798826 0.24 ENST00000540203.1
exportin, tRNA
chr10_-_99447024 0.24 ENST00000370626.3
arginine vasopressin-induced 1
chrX_+_77166172 0.23 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr18_-_21017817 0.23 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
transmembrane protein 241
chr4_+_165675197 0.23 ENST00000515485.1
RP11-294O2.2
chr11_+_5710919 0.23 ENST00000379965.3
ENST00000425490.1
tripartite motif containing 22
chr7_-_86849883 0.23 ENST00000433078.1
transmembrane protein 243, mitochondrial
chr11_-_121986923 0.23 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr13_+_19756173 0.23 ENST00000382988.2
RP11-408E5.4
chr3_+_129207033 0.23 ENST00000507221.1
intraflagellar transport 122 homolog (Chlamydomonas)
chr19_+_17858509 0.23 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCH domain only 1
chr4_+_66536248 0.23 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
chrX_+_15525426 0.23 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr6_-_33385854 0.23 ENST00000488478.1
cutA divalent cation tolerance homolog (E. coli)
chr5_-_147286065 0.22 ENST00000318315.4
ENST00000515291.1
chromosome 5 open reading frame 46
chr12_-_21654479 0.22 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RecQ protein-like (DNA helicase Q1-like)
chr5_-_82969363 0.22 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr17_-_74733404 0.22 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
serine/arginine-rich splicing factor 2
chr22_-_42343117 0.22 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr5_+_161277603 0.22 ENST00000519621.1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_-_51071302 0.22 ENST00000389201.3
ENST00000600381.1
leucine rich repeat containing 4B
chr3_-_112693865 0.22 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200 receptor 1
chr7_+_150782945 0.22 ENST00000463381.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr13_-_76111945 0.22 ENST00000355801.4
ENST00000406936.3
COMM domain containing 6
chr8_+_133975231 0.21 ENST00000518058.1
thyroglobulin
chr11_+_77532233 0.21 ENST00000525409.1
adipogenesis associated, Mth938 domain containing
chr1_+_145438469 0.20 ENST00000369317.4
thioredoxin interacting protein
chr3_-_160823040 0.20 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.6 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.3 1.0 GO:0042270 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.3 1.7 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.3 4.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 0.8 GO:0010877 lipid transport involved in lipid storage(GO:0010877)
0.2 0.6 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 1.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.9 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.8 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 1.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.6 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 1.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:0036289 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) peptidyl-serine autophosphorylation(GO:0036289) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) mRNA endonucleolytic cleavage involved in unfolded protein response(GO:0070055)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.2 GO:0034759 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) cellular response to lead ion(GO:0071284)
0.1 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.5 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.2 GO:0090340 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.1 0.4 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 5.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.4 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.6 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.4 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 1.1 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.0 GO:0014717 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 1.2 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.5 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0002347 response to tumor cell(GO:0002347)
0.0 1.6 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.3 GO:0002292 T cell differentiation involved in immune response(GO:0002292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.3 1.7 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.2 0.7 GO:0097679 other organism cytoplasm(GO:0097679)
0.2 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.9 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 0.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.3 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.1 1.3 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0 0.7 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.6 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 2.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 1.6 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 0.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 1.0 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 0.6 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.8 GO:0046979 TAP2 binding(GO:0046979)
0.1 0.7 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.3 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.1 0.6 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 1.0 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 1.5 GO:0043295 glutathione binding(GO:0043295)
0.1 0.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.2 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 1.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.2 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 1.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.9 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.7 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 6.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 2.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB