Motif ID: LHX8

Z-value: 1.108


Transcription factors associated with LHX8:

Gene SymbolEntrez IDGene Name
LHX8 ENSG00000162624.10 LHX8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX8hg19_v2_chr1_+_75594119_75594119-0.271.4e-01Click!


Activity profile for motif LHX8.

activity profile for motif LHX8


Sorted Z-values histogram for motif LHX8

Sorted Z-values for motif LHX8



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_54982420 2.323 ENST00000257905.8
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_145413268 2.270 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2



hemochromatosis type 2 (juvenile)



chr2_+_168043793 1.582 ENST00000409273.1
ENST00000409605.1
XIRP2

xin actin-binding repeat containing 2

chr10_+_69869237 1.419 ENST00000373675.3
MYPN
myopalladin
chr12_-_54982300 1.361 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr7_-_120498357 1.342 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr12_+_101988627 1.278 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr8_+_9009296 1.150 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr12_+_101988774 1.141 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1





myosin binding protein C, slow type





chr2_-_183291741 1.109 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chrX_-_21776281 0.962 ENST00000379494.3
SMPX
small muscle protein, X-linked
chrX_-_73051037 0.931 ENST00000445814.1
XIST
X inactive specific transcript (non-protein coding)
chr4_+_74275057 0.895 ENST00000511370.1
ALB
albumin
chr8_-_82608409 0.891 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr8_-_25902876 0.868 ENST00000520164.1
EBF2
early B-cell factor 2
chr4_-_100242549 0.859 ENST00000305046.8
ENST00000394887.3
ADH1B

alcohol dehydrogenase 1B (class I), beta polypeptide

chr5_+_140235469 0.844 ENST00000506939.2
ENST00000307360.5
PCDHA10

protocadherin alpha 10

chr8_-_82395461 0.842 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_4535233 0.837 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr2_+_234621551 0.830 ENST00000373414.3
ENST00000608381.1
UGT1A5
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A5
UDP glucuronosyltransferase 1 family, polypeptide A8
chr8_+_19759228 0.817 ENST00000520959.1
LPL
lipoprotein lipase
chr7_-_137028534 0.799 ENST00000348225.2
PTN
pleiotrophin
chr2_-_225266802 0.791 ENST00000243806.2
FAM124B
family with sequence similarity 124B
chr21_+_39644305 0.788 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_166300084 0.763 ENST00000402744.4
CPE
carboxypeptidase E
chr7_-_137028498 0.735 ENST00000393083.2
PTN
pleiotrophin
chr19_-_58204128 0.721 ENST00000597520.1
AC004017.1
Uncharacterized protein
chr12_+_48516357 0.702 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM


phosphofructokinase, muscle


chr4_-_69111401 0.700 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr15_-_34880646 0.698 ENST00000543376.1
GOLGA8A
golgin A8 family, member A
chr6_-_123958141 0.690 ENST00000334268.4
TRDN
triadin
chr4_-_186734275 0.688 ENST00000456060.1
SORBS2
sorbin and SH3 domain containing 2
chrX_+_84258832 0.687 ENST00000373173.2
APOOL
apolipoprotein O-like
chr1_+_47603109 0.681 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22


cytochrome P450, family 4, subfamily A, polypeptide 22


chr1_-_217262933 0.673 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr6_-_24489842 0.649 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr18_+_71815743 0.646 ENST00000169551.6
ENST00000580087.1
TIMM21

translocase of inner mitochondrial membrane 21 homolog (yeast)

chr10_+_24738355 0.640 ENST00000307544.6
KIAA1217
KIAA1217
chr11_-_117800080 0.635 ENST00000524993.1
ENST00000528626.1
ENST00000445164.2
ENST00000430170.2
ENST00000526090.1
TMPRSS13




transmembrane protease, serine 13




chrX_-_5644225 0.630 ENST00000422914.1
RP11-733O18.1
RP11-733O18.1
chr5_+_140593509 0.614 ENST00000341948.4
PCDHB13
protocadherin beta 13
chrX_+_70798261 0.610 ENST00000373696.3
ACRC
acidic repeat containing
chr13_+_24883703 0.610 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr14_-_36990354 0.606 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr1_+_95616933 0.606 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr12_+_48516463 0.603 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr1_-_217262969 0.601 ENST00000361525.3
ESRRG
estrogen-related receptor gamma
chr4_-_186733363 0.595 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2


sorbin and SH3 domain containing 2


chr4_-_110723134 0.575 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr5_+_135170331 0.571 ENST00000425402.1
ENST00000274513.5
ENST00000420621.1
ENST00000433282.2
ENST00000412661.2
SLC25A48




solute carrier family 25, member 48




chr3_+_154798162 0.571 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr1_+_70876926 0.558 ENST00000370938.3
ENST00000346806.2
CTH

cystathionase (cystathionine gamma-lyase)

chr4_+_155484103 0.556 ENST00000302068.4
FGB
fibrinogen beta chain
chr22_+_22516550 0.535 ENST00000390284.2
IGLV4-60
immunoglobulin lambda variable 4-60
chr8_+_101349823 0.534 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr6_+_153071925 0.532 ENST00000367244.3
ENST00000367243.3
VIP

vasoactive intestinal peptide

chr6_-_56507586 0.528 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST




dystonin




chr21_-_34863998 0.527 ENST00000402202.1
ENST00000381947.3
DNAJC28

DnaJ (Hsp40) homolog, subfamily C, member 28

chr18_-_11908272 0.525 ENST00000592977.1
ENST00000590501.1
ENST00000586844.1
MPPE1


metallophosphoesterase 1


chr2_+_201994208 0.519 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr2_+_102758210 0.513 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr4_-_110723335 0.506 ENST00000394634.2
CFI
complement factor I
chr4_-_110723194 0.496 ENST00000394635.3
CFI
complement factor I
chr9_-_70490107 0.492 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5




COBW domain containing 5




chr11_+_60048004 0.492 ENST00000532114.1
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr1_+_144989309 0.489 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr12_-_15038779 0.485 ENST00000228938.5
ENST00000539261.1
MGP

matrix Gla protein

chr18_-_11908329 0.482 ENST00000344987.7
ENST00000588103.1
ENST00000588191.1
ENST00000317235.7
ENST00000309976.9
ENST00000588186.1
ENST00000589267.1
MPPE1






metallophosphoesterase 1






chr11_+_60048129 0.473 ENST00000355131.3
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr2_+_102758271 0.472 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr9_+_70856899 0.471 ENST00000377342.5
ENST00000478048.1
CBWD3

COBW domain containing 3

chr6_-_44400720 0.462 ENST00000595057.1
AL133262.1
AL133262.1
chr7_+_151791095 0.461 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr10_+_81892347 0.454 ENST00000372267.2
PLAC9
placenta-specific 9
chr9_-_13165457 0.448 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ


multiple PDZ domain protein


chr1_+_53662101 0.446 ENST00000371486.3
CPT2
carnitine palmitoyltransferase 2
chr6_+_143759575 0.446 ENST00000595616.1
AL031320.1
AL031320.1
chr9_-_69262509 0.446 ENST00000377449.1
ENST00000382399.4
ENST00000377439.1
ENST00000377441.1
ENST00000377457.5
CBWD6




COBW domain containing 6




chr1_+_230138476 0.446 ENST00000445339.1
RP11-552D4.1
RP11-552D4.1
chr21_-_16254231 0.440 ENST00000412426.1
ENST00000418954.1
AF127936.7

AF127936.7

chr2_+_114195268 0.440 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2


COBW domain containing 2


chr6_-_123958111 0.440 ENST00000542443.1
TRDN
triadin
chr19_+_12175504 0.435 ENST00000439326.3
ZNF844
zinc finger protein 844
chr8_-_62602327 0.434 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr14_+_57046500 0.433 ENST00000261556.6
TMEM260
transmembrane protein 260
chr2_+_201994042 0.431 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_-_30013748 0.426 ENST00000607315.1
RP11-51J9.5
RP11-51J9.5
chr1_-_212004090 0.426 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr17_+_58018269 0.425 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr7_+_114055052 0.424 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr12_-_14967095 0.423 ENST00000316048.2
SMCO3
single-pass membrane protein with coiled-coil domains 3
chr2_-_152830441 0.416 ENST00000534999.1
ENST00000397327.2
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr1_-_168464875 0.416 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr9_-_179018 0.414 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1







COBW domain containing 1







chr12_+_59989918 0.413 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr2_+_108145913 0.413 ENST00000443205.1
AC096669.3
AC096669.3
chr2_-_14541060 0.411 ENST00000418420.1
ENST00000417751.1
LINC00276

long intergenic non-protein coding RNA 276

chr9_+_70856397 0.409 ENST00000360171.6
CBWD3
COBW domain containing 3
chr22_+_23487513 0.403 ENST00000263116.2
ENST00000341989.4
RAB36

RAB36, member RAS oncogene family

chr16_-_20338748 0.403 ENST00000575582.1
ENST00000341642.5
ENST00000381362.4
ENST00000572347.1
ENST00000572478.1
ENST00000302555.5
GP2





glycoprotein 2 (zymogen granule membrane)





chr9_-_20622478 0.401 ENST00000355930.6
ENST00000380338.4
MLLT3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr9_-_5833027 0.398 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr3_+_195447738 0.397 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chrX_-_131262048 0.390 ENST00000298542.4
FRMD7
FERM domain containing 7
chr6_+_32006042 0.387 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr4_-_109684120 0.386 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL



ethanolamine-phosphate phospho-lyase



chr14_+_57046530 0.385 ENST00000536419.1
ENST00000538838.1
TMEM260

transmembrane protein 260

chr4_+_155484155 0.379 ENST00000509493.1
FGB
fibrinogen beta chain
chr8_-_112039643 0.376 ENST00000524283.1
RP11-946L20.2
RP11-946L20.2
chr3_-_151102529 0.376 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr6_-_4347271 0.363 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr7_+_141408153 0.360 ENST00000397541.2
WEE2
WEE1 homolog 2 (S. pombe)
chr3_+_173116225 0.356 ENST00000457714.1
NLGN1
neuroligin 1
chr6_+_26087646 0.355 ENST00000309234.6
HFE
hemochromatosis
chr2_-_152830479 0.354 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr6_+_26087509 0.354 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE









hemochromatosis









chr6_-_75828774 0.349 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr7_+_7811992 0.345 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr7_+_151791074 0.334 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr6_+_76599809 0.331 ENST00000430435.1
MYO6
myosin VI
chr11_+_1049862 0.330 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr2_-_136678123 0.329 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr16_-_20339123 0.324 ENST00000381360.5
GP2
glycoprotein 2 (zymogen granule membrane)
chr11_-_115127611 0.322 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr11_+_72975524 0.316 ENST00000540342.1
ENST00000542092.1
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr16_+_22217577 0.314 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr20_+_56964169 0.313 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr15_+_86805875 0.306 ENST00000389298.3
AGBL1
ATP/GTP binding protein-like 1
chr15_+_65843130 0.303 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_-_225266711 0.297 ENST00000389874.3
FAM124B
family with sequence similarity 124B
chr7_-_92777606 0.297 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr8_-_141810634 0.297 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2


protein tyrosine kinase 2


chr10_+_75668916 0.296 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr12_-_88974236 0.291 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr2_-_225266743 0.285 ENST00000409685.3
FAM124B
family with sequence similarity 124B
chrX_+_73164167 0.277 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX





JPX transcript, XIST activator (non-protein coding)





chr8_+_17354617 0.277 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_-_152623231 0.272 ENST00000540663.1
ENST00000537033.1
SYNE1

spectrin repeat containing, nuclear envelope 1

chr9_+_108424738 0.271 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr19_+_34856078 0.269 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI


glucose-6-phosphate isomerase


chr12_-_10766184 0.269 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB


mago-nashi homolog B (Drosophila)


chr10_-_110321541 0.267 ENST00000366253.2
RP11-163F15.1
RP11-163F15.1
chr5_-_41213607 0.265 ENST00000337836.5
ENST00000433294.1
C6

complement component 6

chr11_+_60048053 0.265 ENST00000337908.4
MS4A4A
membrane-spanning 4-domains, subfamily A, member 4A
chr12_+_122326630 0.265 ENST00000541212.1
ENST00000340175.5
PSMD9

proteasome (prosome, macropain) 26S subunit, non-ATPase, 9

chr7_+_30589829 0.265 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr14_+_50291993 0.263 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr6_+_10633993 0.261 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr13_-_24895566 0.261 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr15_+_54793169 0.260 ENST00000559093.1
UNC13C
unc-13 homolog C (C. elegans)
chr5_+_140165876 0.257 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr11_-_3400442 0.256 ENST00000429541.2
ENST00000532539.1
ZNF195

zinc finger protein 195

chr11_-_58035732 0.255 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr13_+_38923959 0.253 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1



ubiquitin-fold modifier 1



chr8_+_39806685 0.251 ENST00000389060.4
IDO2
indoleamine 2,3-dioxygenase 2
chrX_+_73164149 0.251 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX




JPX transcript, XIST activator (non-protein coding)




chr12_-_39734783 0.250 ENST00000552961.1
KIF21A
kinesin family member 21A
chr1_+_66796401 0.249 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_150612089 0.248 ENST00000397891.3
FAM188B2
family with sequence similarity 188, member B2
chrX_-_23926004 0.248 ENST00000379226.4
ENST00000379220.3
APOO

apolipoprotein O

chr2_+_216946589 0.247 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169





transmembrane protein 169





chr1_-_95391315 0.247 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr11_+_72975578 0.246 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr3_-_47934234 0.245 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr18_-_74839891 0.244 ENST00000581878.1
MBP
myelin basic protein
chr4_-_69083720 0.244 ENST00000432593.3
TMPRSS11BNL
TMPRSS11B N-terminal like
chr3_-_87842631 0.243 ENST00000462792.1
RP11-451B8.1
RP11-451B8.1
chr1_+_145883868 0.242 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr3_+_148545586 0.241 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr1_-_110933611 0.235 ENST00000472422.2
ENST00000437429.2
SLC16A4

solute carrier family 16, member 4

chr1_-_110933663 0.234 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4


solute carrier family 16, member 4


chr2_+_86947296 0.234 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr19_+_12175535 0.232 ENST00000550826.1
ZNF844
zinc finger protein 844
chr8_+_119294456 0.230 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr2_-_37068530 0.227 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr7_-_22234381 0.226 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr12_+_26348246 0.221 ENST00000422622.2
SSPN
sarcospan
chr2_+_234826016 0.218 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chr19_+_42037433 0.218 ENST00000599316.1
ENST00000599770.1
AC006129.1

AC006129.1

chr6_+_43543942 0.218 ENST00000372226.1
ENST00000443535.1
POLH

polymerase (DNA directed), eta

chr7_-_20256965 0.217 ENST00000400331.5
ENST00000332878.4
MACC1

metastasis associated in colon cancer 1

chr7_+_151791037 0.212 ENST00000419245.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr5_+_140480083 0.211 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr5_+_147715119 0.205 ENST00000377906.1
SPINK9
serine peptidase inhibitor, Kazal type 9
chr9_+_96846740 0.204 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr19_+_34855925 0.201 ENST00000590375.1
ENST00000356487.5
GPI

glucose-6-phosphate isomerase

chr8_+_17354587 0.197 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr17_-_3301704 0.192 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr11_-_104817919 0.191 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr10_+_135207598 0.190 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr19_+_34855874 0.189 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr3_-_187455680 0.189 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr19_+_21688366 0.188 ENST00000358491.4
ENST00000597078.1
ZNF429

zinc finger protein 429

chr7_-_7575477 0.187 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr19_+_21264980 0.187 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714




zinc finger protein 714




chr11_+_72975559 0.187 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chrX_+_56258844 0.179 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr1_-_146040968 0.174 ENST00000401010.3
NBPF11
neuroblastoma breakpoint family, member 11
chr1_-_247242048 0.173 ENST00000366503.2
ZNF670
zinc finger protein 670
chr5_-_150473127 0.171 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001907 cytolysis by symbiont of host cells(GO:0001897) killing by symbiont of host cells(GO:0001907) hemolysis by symbiont of host erythrocytes(GO:0019836) disruption by symbiont of host cell(GO:0044004) hemolysis in other organism(GO:0044179) cytolysis in other organism(GO:0051715) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.3 0.8 GO:1901142 insulin processing(GO:0030070) insulin metabolic process(GO:1901142)
0.2 0.8 GO:0006789 bilirubin conjugation(GO:0006789) biphenyl metabolic process(GO:0018879) biphenyl catabolic process(GO:0070980)
0.1 1.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.6 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.8 GO:0034371 chylomicron remodeling(GO:0034371)
0.1 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.6 GO:0042696 menarche(GO:0042696)
0.1 0.4 GO:0006848 pyruvate transport(GO:0006848)
0.1 1.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 1.0 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601) regulation of glutamate receptor signaling pathway(GO:1900449) regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310) regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.7 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.1 0.4 GO:0060013 righting reflex(GO:0060013)
0.1 0.3 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969) positive regulation of activation of membrane attack complex(GO:0001970) positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.3 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.5 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.9 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.7 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 3.7 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.4 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 1.7 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 2.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0014022 planar cell polarity pathway involved in axis elongation(GO:0003402) neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.8 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.3 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0006824 cobalt ion transport(GO:0006824) cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.0 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.0 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769)
0.0 0.3 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0016601 Rac protein signal transduction(GO:0016601)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 2.4 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.1 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.6 GO:0030054 cell junction(GO:0030054)
0.0 0.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.3 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 1.4 GO:0030017 sarcomere(GO:0030017)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.9 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.4 GO:0031432 titin binding(GO:0031432)
0.2 0.8 GO:0017129 triglyceride binding(GO:0017129)
0.1 1.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.7 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.1 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 1.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0034235 GPI anchor binding(GO:0034235)
0.1 1.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.4 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.9 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.9 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.3 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.6 GO:0004630 phospholipase D activity(GO:0004630)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.9 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 2.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway