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Illumina Body Map 2: averaged replicates

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Results for MAF_NRL

Z-value: 1.83

Motif logo

Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
ENSG00000178573.6 MAF
ENSG00000129535.8 NRL

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFhg19_v2_chr16_-_79633799_79633872-0.134.9e-01Click!
NRLhg19_v2_chr14_-_24553834_24553850-0.086.8e-01Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_57431679 6.95 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr11_+_116700600 6.02 ENST00000227667.3
APOC3
apolipoprotein C-III
chr11_+_116700614 5.97 ENST00000375345.1
APOC3
apolipoprotein C-III
chr5_-_156390230 4.67 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr22_+_21128167 3.71 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_+_233749739 3.24 ENST00000366621.3
KCNK1
potassium channel, subfamily K, member 1
chr9_-_116840728 2.87 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr10_+_96443378 2.79 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr14_-_106237742 2.79 ENST00000390551.2
IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_22712087 2.71 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr2_-_89385283 2.50 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr4_+_100495864 2.32 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr1_-_201368653 2.32 ENST00000367313.3
LAD1
ladinin 1
chr10_+_96443204 2.29 ENST00000339022.5
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr21_+_44589118 2.16 ENST00000291554.2
CRYAA
crystallin, alpha A
chr1_-_201368707 2.13 ENST00000391967.2
LAD1
ladinin 1
chr2_+_90458201 2.10 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr2_-_89568263 2.08 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr17_+_41052808 2.07 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr14_-_106114739 2.01 ENST00000460164.1
RP11-731F5.2
RP11-731F5.2
chr22_+_22385332 2.00 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr16_+_32859034 1.95 ENST00000567458.2
ENST00000560724.1
IGHV2OR16-5
immunoglobulin heavy variable 2/OR16-5 (non-functional)
chr9_+_139839686 1.90 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr20_+_45338126 1.90 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_-_53297432 1.86 ENST00000546900.1
KRT8
keratin 8
chr1_-_157811588 1.86 ENST00000368174.4
CD5L
CD5 molecule-like
chr3_+_184097836 1.85 ENST00000204604.1
ENST00000310236.3
CHRD
chordin
chr3_-_50340996 1.83 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr3_+_184097905 1.82 ENST00000450923.1
CHRD
chordin
chr11_-_2924720 1.80 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_+_77774897 1.79 ENST00000281030.2
THRSP
thyroid hormone responsive
chr3_+_184098065 1.79 ENST00000348986.3
CHRD
chordin
chr2_-_20425158 1.78 ENST00000381150.1
SDC1
syndecan 1
chr2_+_234600253 1.78 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr18_+_29171689 1.77 ENST00000237014.3
TTR
transthyretin
chr4_+_42399856 1.71 ENST00000319234.4
SHISA3
shisa family member 3
chr20_-_48099182 1.67 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr6_+_31895467 1.66 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr22_+_22516550 1.65 ENST00000390284.2
IGLV4-60
immunoglobulin lambda variable 4-60
chr17_-_54893250 1.63 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr19_+_45417921 1.61 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr19_+_45417504 1.61 ENST00000588750.1
ENST00000588802.1
APOC1
apolipoprotein C-I
chr19_+_45418067 1.58 ENST00000589078.1
ENST00000586638.1
APOC1
apolipoprotein C-I
chr22_+_23222886 1.58 ENST00000390319.2
IGLV3-1
immunoglobulin lambda variable 3-1
chr2_-_188419078 1.57 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr9_+_27109392 1.56 ENST00000406359.4
TEK
TEK tyrosine kinase, endothelial
chr22_+_22730353 1.54 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr20_+_36974759 1.53 ENST00000217407.2
LBP
lipopolysaccharide binding protein
chr2_-_188419200 1.53 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr18_-_25616519 1.51 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_22559211 1.48 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr2_+_89184868 1.46 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr3_+_52828805 1.43 ENST00000416872.2
ENST00000449956.2
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chrX_+_123480375 1.42 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr6_+_143381979 1.41 ENST00000367598.5
ENST00000447498.1
ENST00000357847.4
ENST00000344492.5
ENST00000367596.1
ENST00000494282.2
ENST00000275235.4
AIG1
androgen-induced 1
chr5_+_1201703 1.41 ENST00000304460.10
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr14_-_107179265 1.41 ENST00000390634.2
IGHV2-70
immunoglobulin heavy variable 2-70
chr2_+_120187465 1.40 ENST00000409826.1
ENST00000417645.1
TMEM37
transmembrane protein 37
chr9_+_27109440 1.37 ENST00000519080.1
TEK
TEK tyrosine kinase, endothelial
chr16_+_57438679 1.36 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr7_-_14028488 1.36 ENST00000405358.4
ETV1
ets variant 1
chrX_+_123480194 1.35 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr12_-_102874330 1.32 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr2_+_231902193 1.30 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr19_-_7812446 1.30 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr12_+_103981044 1.30 ENST00000388887.2
STAB2
stabilin 2
chr3_+_186330712 1.27 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr6_+_31895480 1.26 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895254 1.24 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr19_+_45417812 1.24 ENST00000592535.1
APOC1
apolipoprotein C-I
chr2_+_128180842 1.23 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr5_+_42756903 1.22 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr10_+_96522361 1.21 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr11_-_57004658 1.21 ENST00000606794.1
APLNR
apelin receptor
chr12_-_102874102 1.20 ENST00000392905.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr22_+_23154239 1.19 ENST00000390315.2
IGLV3-10
immunoglobulin lambda variable 3-10
chr6_+_32006042 1.19 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_90273679 1.18 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr22_+_22681656 1.18 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr14_-_106092403 1.17 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr19_-_46476791 1.16 ENST00000263257.5
NOVA2
neuro-oncological ventral antigen 2
chr11_+_22688150 1.16 ENST00000454584.2
GAS2
growth arrest-specific 2
chr22_+_22697537 1.14 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr22_+_22735135 1.14 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr22_+_23029188 1.13 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr17_-_73874654 1.12 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr11_+_74862140 1.12 ENST00000525650.1
ENST00000454962.2
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr2_+_234637754 1.12 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_+_111397216 1.11 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr6_+_31895287 1.10 ENST00000447952.2
C2
complement component 2
chr10_-_44880491 1.10 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
CXCL12
chemokine (C-X-C motif) ligand 12
chr9_+_27109133 1.09 ENST00000519097.1
ENST00000380036.4
TEK
TEK tyrosine kinase, endothelial
chr20_+_34203794 1.09 ENST00000374273.3
SPAG4
sperm associated antigen 4
chr19_-_55895966 1.08 ENST00000444469.3
TMEM238
transmembrane protein 238
chr14_-_106406090 1.08 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr7_-_100239132 1.07 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr7_-_99332719 1.07 ENST00000336374.2
CYP3A7
cytochrome P450, family 3, subfamily A, polypeptide 7
chr22_+_22764088 1.07 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr6_+_32006159 1.04 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr12_+_52626898 1.04 ENST00000331817.5
KRT7
keratin 7
chr6_+_50061315 1.03 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr2_-_190044480 1.03 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_-_106692191 1.01 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr14_-_106878083 1.00 ENST00000390619.2
IGHV4-39
immunoglobulin heavy variable 4-39
chr11_-_116708302 1.00 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr3_-_88108192 0.99 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chrX_-_47479246 0.99 ENST00000295987.7
ENST00000340666.4
SYN1
synapsin I
chr11_-_10590118 0.99 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr22_+_22930626 0.99 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr11_-_10590238 0.99 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr11_-_2182388 0.98 ENST00000421783.1
ENST00000397262.1
ENST00000250971.3
ENST00000381330.4
ENST00000397270.1
INS
INS-IGF2
insulin
INS-IGF2 readthrough
chr22_+_22786288 0.98 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr2_-_89513402 0.98 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr9_-_112260531 0.97 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr3_-_88108212 0.97 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr3_+_50192499 0.96 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_113885138 0.96 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr4_-_57976544 0.95 ENST00000295666.4
ENST00000537922.1
IGFBP7
insulin-like growth factor binding protein 7
chr1_+_171283331 0.94 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr2_-_151344172 0.93 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr2_+_135596106 0.92 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr19_-_58864848 0.92 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr2_+_135596180 0.91 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr14_+_69865401 0.91 ENST00000556605.1
ENST00000336643.5
ENST00000031146.4
SLC39A9
solute carrier family 39, member 9
chr22_+_23235872 0.91 ENST00000390320.2
IGLJ1
immunoglobulin lambda joining 1
chr11_+_22688615 0.91 ENST00000533363.1
GAS2
growth arrest-specific 2
chr22_+_22676808 0.91 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr12_-_14996355 0.90 ENST00000228936.4
ART4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr3_+_50192457 0.89 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_-_23058063 0.88 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
DAD1
defender against cell death 1
chr3_+_185080908 0.87 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr12_+_2079939 0.86 ENST00000543114.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr6_-_25930819 0.84 ENST00000360488.3
SLC17A2
solute carrier family 17, member 2
chr19_-_7812397 0.84 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chr8_+_80523321 0.84 ENST00000518111.1
STMN2
stathmin-like 2
chr21_-_40033618 0.83 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr2_-_74757066 0.83 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chrX_+_17755696 0.83 ENST00000419185.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr11_-_914774 0.83 ENST00000528154.1
ENST00000525840.1
CHID1
chitinase domain containing 1
chr18_-_5197501 0.82 ENST00000580650.1
C18orf42
chromosome 18 open reading frame 42
chr9_+_139746792 0.81 ENST00000317446.2
ENST00000445819.1
MAMDC4
MAM domain containing 4
chrX_+_128913906 0.81 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr10_+_115312825 0.81 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr11_-_2160180 0.81 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_106866934 0.81 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr17_+_27573875 0.80 ENST00000225387.3
CRYBA1
crystallin, beta A1
chr3_+_100328433 0.80 ENST00000273352.3
GPR128
G protein-coupled receptor 128
chr14_-_106518922 0.80 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr6_-_25930904 0.79 ENST00000377850.3
SLC17A2
solute carrier family 17, member 2
chr9_-_128003606 0.78 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr22_+_22749343 0.78 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr12_-_102874416 0.78 ENST00000392904.1
ENST00000337514.6
IGF1
insulin-like growth factor 1 (somatomedin C)
chr14_-_106791536 0.77 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr14_-_107199464 0.76 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr17_-_38520067 0.76 ENST00000337376.4
ENST00000578689.1
GJD3
gap junction protein, delta 3, 31.9kDa
chr21_-_45671014 0.75 ENST00000436357.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr20_+_42187682 0.75 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr11_-_12030905 0.75 ENST00000326932.4
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr9_-_13175823 0.75 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr18_-_64271363 0.74 ENST00000262150.2
CDH19
cadherin 19, type 2
chr22_+_25595817 0.74 ENST00000215855.2
ENST00000404334.1
CRYBB3
crystallin, beta B3
chr15_-_40212363 0.73 ENST00000299092.3
GPR176
G protein-coupled receptor 176
chr11_+_101983176 0.73 ENST00000524575.1
YAP1
Yes-associated protein 1
chr4_+_154125565 0.73 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr16_-_28518153 0.72 ENST00000356897.1
IL27
interleukin 27
chr13_+_93879085 0.72 ENST00000377047.4
GPC6
glypican 6
chr6_-_138866823 0.71 ENST00000342260.5
NHSL1
NHS-like 1
chr7_-_41742697 0.71 ENST00000242208.4
INHBA
inhibin, beta A
chr7_-_94285472 0.71 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr7_-_8302298 0.71 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr7_+_26331541 0.70 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10
sorting nexin 10
chr10_-_50970322 0.70 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr12_+_56075330 0.70 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr7_+_65540853 0.70 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr1_-_119869846 0.69 ENST00000457719.1
RP11-418J17.3
RP11-418J17.3
chr5_+_63802109 0.69 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr4_+_39408470 0.69 ENST00000257408.4
KLB
klotho beta
chrX_+_17755563 0.69 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr10_-_98031265 0.68 ENST00000224337.5
ENST00000371176.2
BLNK
B-cell linker
chr3_+_38388251 0.68 ENST00000427323.1
ENST00000207870.3
ENST00000542835.1
XYLB
xylulokinase homolog (H. influenzae)
chr16_-_28550348 0.68 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr5_-_138718973 0.67 ENST00000353963.3
ENST00000348729.3
SLC23A1
solute carrier family 23 (ascorbic acid transporter), member 1
chr6_-_24489842 0.67 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr15_+_96875657 0.67 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr1_+_61869748 0.65 ENST00000357977.5
NFIA
nuclear factor I/A
chr12_-_102874378 0.65 ENST00000456098.1
IGF1
insulin-like growth factor 1 (somatomedin C)
chr11_-_2924970 0.65 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr16_+_777739 0.64 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr12_-_92539614 0.64 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr3_+_50192537 0.64 ENST00000002829.3
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr22_-_38240412 0.63 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr16_+_226658 0.63 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr7_-_8301869 0.63 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr16_+_2510081 0.62 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
C16orf59
chromosome 16 open reading frame 59
chr8_+_30244580 0.62 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr17_-_56494882 0.62 ENST00000584437.1
RNF43
ring finger protein 43
chr17_+_41003166 0.62 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr7_-_128415844 0.62 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_-_160832642 0.61 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr6_-_133035185 0.61 ENST00000367928.4
VNN1
vanin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
1.8 5.5 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
1.5 6.0 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
1.0 1.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.8 3.9 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6 1.8 GO:0048627 myoblast development(GO:0048627)
0.5 3.7 GO:0008218 bioluminescence(GO:0008218)
0.5 1.6 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 3.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.5 11.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 2.1 GO:0046968 peptide antigen transport(GO:0046968)
0.4 1.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.4 3.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 1.8 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.3 1.0 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) glomerular endothelium development(GO:0072011)
0.3 1.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3 1.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.3 1.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 3.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.3 4.2 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 1.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 0.8 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 1.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0060279 positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.2 0.7 GO:0042732 D-xylose metabolic process(GO:0042732)
0.2 6.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 0.7 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 1.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.2 0.8 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 2.9 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.2 0.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.2 31.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.8 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 1.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 2.3 GO:0034378 chylomicron assembly(GO:0034378)
0.2 0.6 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.2 0.7 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.2 1.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.2 2.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.2 GO:0001554 luteolysis(GO:0001554)
0.2 0.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.5 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.2 3.4 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 1.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.1 1.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.9 GO:0051414 response to cortisol(GO:0051414)
0.1 0.4 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development(GO:0035607)
0.1 0.9 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.5 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0042214 terpene metabolic process(GO:0042214)
0.1 1.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.5 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.4 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.4 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 0.5 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.3 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.5 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.3 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.9 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 1.0 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 1.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.4 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 3.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 1.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.3 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.2 GO:0002125 maternal aggressive behavior(GO:0002125)
0.1 2.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 1.6 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.5 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.2 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 1.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.1 0.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 2.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.4 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.2 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.8 GO:0050957 equilibrioception(GO:0050957)
0.1 0.6 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 1.8 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.1 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.1 0.3 GO:0034241 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.1 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.1 0.7 GO:0097475 motor neuron migration(GO:0097475)
0.1 0.8 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.5 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:0042853 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.1 0.7 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 12.7 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.2 GO:0003335 corneocyte development(GO:0003335)
0.1 0.4 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.1 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.3 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0035567 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164) non-canonical Wnt signaling pathway(GO:0035567)
0.1 0.2 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.1 GO:0060278 regulation of ovulation(GO:0060278)
0.1 0.5 GO:0035768 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 0.6 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.9 GO:0016264 gap junction assembly(GO:0016264)
0.0 2.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.8 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 1.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.9 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0097501 stress response to metal ion(GO:0097501)
0.0 1.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 1.9 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 1.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 1.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0005976 polysaccharide metabolic process(GO:0005976)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.1 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.8 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.5 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.1 GO:1900673 cellular alkene metabolic process(GO:0043449) olefin metabolic process(GO:1900673)
0.0 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.5 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.2 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.9 GO:0006525 arginine metabolic process(GO:0006525)
0.0 0.9 GO:0060074 synapse maturation(GO:0060074)
0.0 1.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.1 GO:0070244 negative regulation of thymocyte apoptotic process(GO:0070244)
0.0 0.1 GO:0050818 regulation of coagulation(GO:0050818)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0050777 negative regulation of immune response(GO:0050777)
0.0 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.7 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0030208 dermatan sulfate metabolic process(GO:0030205) dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.3 GO:0007411 axon guidance(GO:0007411)
0.0 0.2 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.3 GO:0007519 skeletal muscle tissue development(GO:0007519) skeletal muscle organ development(GO:0060538)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.5 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 1.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.3 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.1 GO:0002727 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727) negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.6 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.4 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 1.5 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 1.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.0 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:1903206 negative regulation of response to reactive oxygen species(GO:1901032) negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.0 0.2 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.6 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0015893 drug transport(GO:0015893)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.9 8.9 GO:0005579 membrane attack complex(GO:0005579)
0.6 3.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.6 1.8 GO:0036117 hyaluranon cable(GO:0036117)
0.4 3.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.3 6.4 GO:0042627 chylomicron(GO:0042627)
0.2 0.7 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 10.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 1.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 6.0 GO:0009925 basal plasma membrane(GO:0009925)
0.1 18.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.3 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 1.5 GO:0016342 catenin complex(GO:0016342)
0.1 3.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.6 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 0.5 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.3 GO:0070701 mucus layer(GO:0070701)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 6.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0097227 sperm annulus(GO:0097227)
0.0 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 4.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 4.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 34.3 GO:0005615 extracellular space(GO:0005615)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 13.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.8 6.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.7 2.9 GO:0019862 IgA binding(GO:0019862)
0.5 5.5 GO:0045545 syndecan binding(GO:0045545)
0.5 2.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.4 1.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.4 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 6.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 1.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.9 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.2 0.7 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 2.1 GO:0046790 virion binding(GO:0046790)
0.2 0.6 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 1.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 0.5 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 1.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.2 1.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.8 GO:0008422 beta-glucosidase activity(GO:0008422)
0.2 0.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 9.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 3.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 3.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 4.8 GO:0001848 complement binding(GO:0001848)
0.1 28.4 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 6.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 3.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.0 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 2.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.1 0.9 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.6 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.5 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.2 GO:0031893 vasopressin receptor binding(GO:0031893)
0.1 1.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.9 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.3 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.9 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.0 GO:0043199 sulfate binding(GO:0043199)
0.1 0.4 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 0.3 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.4 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 9.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.7 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 4.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.9 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 1.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 3.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 3.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 2.3 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 1.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 3.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.5 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0 0.0 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.0 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 3.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 8.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.6 PID BMP PATHWAY BMP receptor signaling
0.1 4.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 6.3 PID SHP2 PATHWAY SHP2 signaling
0.0 3.1 PID FGF PATHWAY FGF signaling pathway
0.0 1.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 10.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID P73PATHWAY p73 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.4 7.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 14.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 4.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.4 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.1 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.8 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)