Motif ID: MEF2D_MEF2A

Z-value: 7.990

Transcription factors associated with MEF2D_MEF2A:

Gene SymbolEntrez IDGene Name
MEF2A ENSG00000068305.13 MEF2A
MEF2D ENSG00000116604.13 MEF2D

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEF2Ahg19_v2_chr15_+_100106244_1001062920.421.6e-02Click!
MEF2Dhg19_v2_chr1_-_156460391_1564604170.402.5e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2D_MEF2A

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_19223523 72.822 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr7_-_113559104 68.713 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr1_-_201391149 59.710 ENST00000555948.1
ENST00000556362.1
TNNI1

troponin I type 1 (skeletal, slow)

chr2_+_168043793 59.444 ENST00000409273.1
ENST00000409605.1
XIRP2

xin actin-binding repeat containing 2

chr17_+_37821593 59.337 ENST00000578283.1
TCAP
titin-cap
chr6_-_123957942 59.296 ENST00000398178.3
TRDN
triadin
chr6_-_123958051 55.868 ENST00000546248.1
TRDN
triadin
chr2_+_88367299 55.777 ENST00000419482.2
ENST00000444564.2
SMYD1

SET and MYND domain containing 1

chr16_-_31439735 54.770 ENST00000287490.4
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr10_-_115423792 53.968 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP



nebulin-related anchoring protein



chr12_-_111358372 51.772 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr6_-_123958111 51.217 ENST00000542443.1
TRDN
triadin
chr2_-_211168332 50.560 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chrX_-_21776281 48.598 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr3_-_39234074 48.357 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1


xin actin-binding repeat containing 1


chr2_+_88367368 47.877 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr5_+_53751445 41.605 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr1_-_917497 41.306 ENST00000433179.2
C1orf170
chromosome 1 open reading frame 170
chr10_+_50507232 40.453 ENST00000374144.3
C10orf71
chromosome 10 open reading frame 71
chr5_+_191592 38.210 ENST00000328278.3
LRRC14B
leucine rich repeat containing 14B
chr1_-_917466 36.992 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr10_+_50507181 36.787 ENST00000323868.4
C10orf71
chromosome 10 open reading frame 71
chr4_+_120056939 33.622 ENST00000307128.5
MYOZ2
myozenin 2
chr10_-_75415825 33.385 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr8_+_1993152 32.650 ENST00000262113.4
MYOM2
myomesin 2
chr22_-_36013368 31.518 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chrX_-_15332665 31.261 ENST00000537676.1
ENST00000344384.4
ASB11

ankyrin repeat and SOCS box containing 11

chr11_+_1942580 30.999 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr3_-_52486841 30.690 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr8_+_1993173 29.871 ENST00000523438.1
MYOM2
myomesin 2
chr22_+_26138108 29.850 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B


myosin XVIIIB


chr1_-_100643765 29.559 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39


leucine rich repeat containing 39


chr10_+_88428370 29.508 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr17_-_9694614 29.241 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr6_-_123958141 29.203 ENST00000334268.4
TRDN
triadin
chr14_-_23877474 28.818 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr12_-_49393092 28.705 ENST00000421952.2
DDN
dendrin
chr2_-_211179883 28.465 ENST00000352451.3
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_+_121311966 28.395 ENST00000338040.4
FBXO40
F-box protein 40
chr1_-_26394114 28.358 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr11_+_1940925 28.171 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
TNNT3





troponin T type 3 (skeletal, fast)





chr7_-_150884332 27.904 ENST00000275838.1
ENST00000422024.1
ENST00000434669.1
ASB10


ankyrin repeat and SOCS box containing 10


chr16_+_31225337 27.516 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr22_-_36018569 26.987 ENST00000419229.1
ENST00000406324.1
MB

myoglobin

chr20_+_61147651 26.286 ENST00000370527.3
ENST00000370524.2
C20orf166

chromosome 20 open reading frame 166

chr11_+_1860200 25.311 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr5_+_78985673 25.087 ENST00000446378.2
CMYA5
cardiomyopathy associated 5
chr12_+_101962128 24.744 ENST00000550514.1
MYBPC1
myosin binding protein C, slow type
chr9_-_97356075 24.464 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr10_+_88428206 24.440 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chrX_-_63450480 24.271 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr3_+_35683651 24.218 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr4_+_119810134 23.958 ENST00000434046.2
SYNPO2
synaptopodin 2
chr1_+_145413268 23.310 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2



hemochromatosis type 2 (juvenile)



chr18_-_3219847 23.272 ENST00000261606.7
MYOM1
myomesin 1
chr2_+_170366203 23.165 ENST00000284669.1
KLHL41
kelch-like family member 41
chr1_-_115238207 23.080 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1


adenosine monophosphate deaminase 1


chr17_-_10421853 22.319 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr18_-_3220106 22.220 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr10_-_75410771 21.911 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr4_+_119809984 21.883 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2


synaptopodin 2


chr1_+_160160283 21.823 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160346 21.749 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr16_+_7382745 21.643 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1



RNA binding protein, fox-1 homolog (C. elegans) 1



chr17_+_7184986 21.256 ENST00000317370.8
ENST00000571308.1
SLC2A4

solute carrier family 2 (facilitated glucose transporter), member 4

chr11_+_57308979 21.102 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr7_-_150884873 20.972 ENST00000377867.3
ASB10
ankyrin repeat and SOCS box containing 10
chr17_+_4855053 20.630 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr19_+_3933085 19.888 ENST00000168977.2
ENST00000599576.1
NMRK2

nicotinamide riboside kinase 2

chr15_+_42651691 19.646 ENST00000357568.3
ENST00000349748.3
ENST00000318023.7
ENST00000397163.3
CAPN3



calpain 3, (p94)



chr2_+_220299547 19.629 ENST00000312358.7
SPEG
SPEG complex locus
chr2_+_103378472 19.435 ENST00000412401.2
TMEM182
transmembrane protein 182
chr19_+_3933579 18.556 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr3_+_42727011 18.118 ENST00000287777.4
KLHL40
kelch-like family member 40
chr6_+_53948221 18.007 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr12_+_101988627 17.481 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr5_-_142077569 17.433 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1


fibroblast growth factor 1 (acidic)


chr6_+_53948328 17.165 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chrX_+_153046456 17.088 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRPK3





SRSF protein kinase 3





chr6_+_41021027 16.995 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr22_-_51017084 16.314 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B


carnitine palmitoyltransferase 1B (muscle)


chr1_-_116311402 15.998 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr22_-_51016846 15.889 ENST00000312108.7
ENST00000395650.2
CPT1B

carnitine palmitoyltransferase 1B (muscle)

chr11_+_1860832 15.498 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr7_-_44105158 15.243 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr3_+_135741576 15.204 ENST00000334546.2
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr1_-_116311323 15.134 ENST00000456138.2
CASQ2
calsequestrin 2 (cardiac muscle)
chr15_+_65369082 15.107 ENST00000432196.2
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr10_-_69455873 14.668 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr12_-_22094336 14.602 ENST00000326684.4
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_+_155753745 14.321 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr3_-_155011483 14.248 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr10_-_69425399 14.153 ENST00000330298.6
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_+_160085567 13.904 ENST00000392233.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_-_201390846 13.879 ENST00000367312.1
ENST00000555340.2
ENST00000361379.4
TNNI1


troponin I type 1 (skeletal, slow)


chr3_-_196242233 13.778 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr1_+_160085501 13.651 ENST00000361216.3
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr1_+_228395755 13.609 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN




obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF




chr2_+_239047337 13.559 ENST00000409223.1
ENST00000305959.4
KLHL30

kelch-like family member 30

chr12_-_22094159 13.558 ENST00000538350.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr17_-_79900255 13.491 ENST00000582198.1
ENST00000330655.3
PYCR1
MYADML2
pyrroline-5-carboxylate reductase 1
myeloid-associated differentiation marker-like 2
chr2_-_97509749 13.326 ENST00000331001.2
ENST00000318357.4
ANKRD23

ankyrin repeat domain 23

chr16_-_4292071 13.096 ENST00000399609.3
SRL
sarcalumenin
chr17_-_41132088 13.046 ENST00000454303.1
ENST00000591916.1
ENST00000451885.2
PTGES3L-AARSD1
PTGES3L

PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 (cytosolic)-like

chr11_+_1860682 12.941 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_97509729 12.938 ENST00000418232.1
ANKRD23
ankyrin repeat domain 23
chr15_-_83474806 12.879 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2


fibronectin type III and SPRY domain containing 2


chr12_+_81101277 12.863 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr12_+_119616447 12.771 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr11_+_1940786 12.757 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3




troponin T type 3 (skeletal, fast)




chr3_+_127634069 12.744 ENST00000405109.1
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr11_-_47374246 12.741 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3


myosin binding protein C, cardiac


chr1_-_216896780 12.712 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG



estrogen-related receptor gamma



chr7_+_143013198 12.482 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_+_3666335 12.377 ENST00000250693.1
ART1
ADP-ribosyltransferase 1
chr8_-_70745575 12.081 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr1_-_40137710 11.846 ENST00000235628.1
NT5C1A
5'-nucleotidase, cytosolic IA
chr14_-_21493884 11.779 ENST00000556974.1
ENST00000554419.1
ENST00000298687.5
ENST00000397858.1
ENST00000360463.3
ENST00000350792.3
ENST00000397847.2
NDRG2






NDRG family member 2






chr17_-_42188598 11.724 ENST00000591714.1
HDAC5
histone deacetylase 5
chr13_+_76378305 11.712 ENST00000526371.1
ENST00000526528.1
LMO7

LIM domain 7

chr1_-_31845914 11.695 ENST00000373713.2
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr4_-_100575781 11.647 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr5_-_16509101 11.480 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr17_-_27949911 11.433 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6


coronin 6


chr3_+_127634312 11.332 ENST00000407609.3
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr7_+_28448995 11.106 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr4_+_186064395 10.998 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr14_-_21493649 10.925 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr2_-_179537145 10.837 ENST00000448510.2
TTN
titin
chr17_+_65040678 10.757 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr2_-_219696519 10.579 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3


protein kinase, AMP-activated, gamma 3 non-catalytic subunit


chr3_+_179370517 10.524 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr10_-_72141330 10.379 ENST00000395011.1
ENST00000395010.1
LRRC20

leucine rich repeat containing 20

chr2_-_219696511 10.295 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr6_-_3912207 10.147 ENST00000566733.1
RP1-140K8.5
RP1-140K8.5
chr4_+_41362796 10.107 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr12_+_52431016 10.091 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr3_-_46904946 9.872 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_-_10372875 9.855 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr3_-_46904918 9.722 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr4_+_95373037 9.654 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5










PDZ and LIM domain 5










chr9_-_85882145 9.632 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_+_35683775 9.623 ENST00000452563.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_+_179149636 9.485 ENST00000409631.1
OSBPL6
oxysterol binding protein-like 6
chr16_+_30075463 9.414 ENST00000562168.1
ENST00000569545.1
ALDOA

aldolase A, fructose-bisphosphate

chr16_+_30075595 9.379 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_57326704 9.256 ENST00000487349.1
ENST00000389601.3
ASB14

ankyrin repeat and SOCS box containing 14

chr9_-_130639997 9.174 ENST00000373176.1
AK1
adenylate kinase 1
chr3_-_192445289 9.081 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr2_+_220283091 9.000 ENST00000373960.3
DES
desmin
chr8_+_67039278 8.937 ENST00000276573.7
ENST00000350034.4
TRIM55

tripartite motif containing 55

chr3_+_138067521 8.731 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chr16_+_6069072 8.729 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr19_+_35630022 8.694 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr9_+_100263912 8.617 ENST00000259365.4
TMOD1
tropomodulin 1
chr12_-_57644952 8.607 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3



SH3 and cysteine rich domain 3



chr1_-_216896674 8.514 ENST00000475275.1
ENST00000469486.1
ENST00000481543.1
ESRRG


estrogen-related receptor gamma


chr3_+_35683816 8.297 ENST00000438577.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr13_+_76378407 8.219 ENST00000447038.1
LMO7
LIM domain 7
chr1_+_150254936 8.125 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
C1orf51


chromosome 1 open reading frame 51


chr14_-_70546897 8.076 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3


solute carrier family 8 (sodium/calcium exchanger), member 3


chr4_-_23891658 8.066 ENST00000507380.1
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr8_+_67039131 8.041 ENST00000315962.4
ENST00000353317.5
TRIM55

tripartite motif containing 55

chr16_+_30075783 8.035 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr13_+_76413852 8.028 ENST00000533809.2
LMO7
LIM domain 7
chr6_-_76203345 7.935 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr5_+_173316341 7.935 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr16_+_30076052 7.931 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chrX_-_138304939 7.865 ENST00000448673.1
FGF13
fibroblast growth factor 13
chr19_+_35630344 7.836 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr4_+_41362615 7.824 ENST00000509638.1
LIMCH1
LIM and calponin homology domains 1
chr4_-_44653636 7.790 ENST00000415895.4
ENST00000332990.5
YIPF7

Yip1 domain family, member 7

chr6_-_76203454 7.786 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr4_+_114066764 7.767 ENST00000511380.1
ANK2
ankyrin 2, neuronal
chr1_+_170633047 7.620 ENST00000239461.6
ENST00000497230.2
PRRX1

paired related homeobox 1

chr11_+_112832090 7.620 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr10_+_86184676 7.444 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr17_-_27467418 7.241 ENST00000528564.1
MYO18A
myosin XVIIIA
chr10_-_14880002 7.118 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr13_+_76210448 7.077 ENST00000377499.5
LMO7
LIM domain 7
chrX_+_70521584 7.043 ENST00000373829.3
ENST00000538820.1
ITGB1BP2

integrin beta 1 binding protein (melusin) 2

chr6_-_45983581 7.021 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr19_+_35629702 7.018 ENST00000351325.4
FXYD1
FXYD domain containing ion transport regulator 1
chr1_-_203144941 7.000 ENST00000255416.4
MYBPH
myosin binding protein H
chr11_+_112832202 6.970 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr22_+_17956618 6.954 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr5_+_133772383 6.863 ENST00000513329.1
AC005355.1
AC005355.1
chr9_-_33402506 6.840 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr6_-_45983549 6.749 ENST00000544153.1
CLIC5
chloride intracellular channel 5
chr3_+_138067314 6.642 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chrX_-_71933888 6.621 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1




phosphorylase kinase, alpha 1 (muscle)




chr19_-_49576198 6.578 ENST00000221444.1
KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
chr7_+_95115210 6.554 ENST00000428113.1
ENST00000325885.5
ASB4

ankyrin repeat and SOCS box containing 4

chr14_-_62217779 6.403 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr8_-_17533838 6.352 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr14_-_21493123 6.318 ENST00000556147.1
ENST00000554489.1
ENST00000555657.1
ENST00000557274.1
ENST00000555158.1
ENST00000554833.1
ENST00000555384.1
ENST00000556420.1
ENST00000554893.1
ENST00000553503.1
ENST00000555733.1
ENST00000553867.1
ENST00000397856.3
ENST00000397855.3
ENST00000556008.1
ENST00000557182.1
ENST00000554483.1
ENST00000556688.1
ENST00000397853.3
ENST00000556329.2
ENST00000554143.1
ENST00000397851.2
ENST00000555142.1
ENST00000557676.1
ENST00000556924.1
NDRG2
























NDRG family member 2
























chr3_+_35721182 6.294 ENST00000413378.1
ENST00000417925.1
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr7_+_15728003 6.203 ENST00000442176.1
AC005550.4
AC005550.4
chr3_+_35680339 6.199 ENST00000450234.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_23751189 6.135 ENST00000374601.3
ENST00000450454.2
TCEA3

transcription elongation factor A (SII), 3


Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 70.2 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
8.7 43.4 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
7.3 58.5 GO:0043353 slow-twitch skeletal muscle fiber contraction(GO:0031444) enucleate erythrocyte differentiation(GO:0043353)
7.2 28.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
5.9 255.2 GO:0006942 regulation of striated muscle contraction(GO:0006942)
4.7 23.7 GO:0001778 plasma membrane repair(GO:0001778)
4.7 14.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
3.8 265.4 GO:0006941 striated muscle contraction(GO:0006941)
3.7 11.0 GO:0060547 negative regulation of necrotic cell death(GO:0060547)
3.5 28.2 GO:0010107 potassium ion import(GO:0010107)
3.5 69.4 GO:0045214 sarcomere organization(GO:0045214)
3.5 72.8 GO:0002026 regulation of the force of heart contraction(GO:0002026)
3.4 17.0 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
2.4 24.5 GO:0006000 fructose metabolic process(GO:0006000)
2.2 6.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
2.1 42.0 GO:1902603 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
1.9 81.4 GO:0034605 cellular response to heat(GO:0034605)
1.8 12.9 GO:0042693 muscle cell fate commitment(GO:0042693)
1.8 80.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.8 12.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
1.5 13.8 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
1.4 12.5 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
1.4 6.8 GO:0070295 renal water absorption(GO:0070295)
1.3 13.5 GO:0006561 proline biosynthetic process(GO:0006561)
1.3 7.9 GO:0007288 sperm axoneme assembly(GO:0007288)
1.3 3.9 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.3 347.1 GO:0006936 muscle contraction(GO:0006936)
1.2 4.6 GO:0042118 endothelial cell activation(GO:0042118)
1.1 5.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.9 5.6 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.9 2.8 GO:0033058 directional locomotion(GO:0033058)
0.9 4.6 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.9 6.3 GO:0048840 otolith development(GO:0048840)
0.9 60.8 GO:0009408 response to heat(GO:0009408)
0.9 23.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.8 4.1 GO:0001757 somite specification(GO:0001757)
0.8 107.3 GO:0006338 chromatin remodeling(GO:0006338)
0.8 72.5 GO:0005977 glycogen metabolic process(GO:0005977)
0.7 16.3 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.6 1.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.6 11.8 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.6 1.7 GO:0090108 regulation of high-density lipoprotein particle assembly(GO:0090107) positive regulation of high-density lipoprotein particle assembly(GO:0090108) regulation of pancreatic juice secretion(GO:0090186) positive regulation of pancreatic juice secretion(GO:0090187)
0.6 25.9 GO:0046323 glucose import(GO:0046323)
0.5 1.6 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) regulation of DNA damage checkpoint(GO:2000001)
0.5 20.9 GO:0046320 regulation of fatty acid oxidation(GO:0046320)
0.5 5.4 GO:0006013 mannose metabolic process(GO:0006013)
0.5 7.6 GO:0042474 middle ear morphogenesis(GO:0042474)
0.4 10.2 GO:0007520 myoblast fusion(GO:0007520)
0.4 4.9 GO:0015693 magnesium ion transport(GO:0015693)
0.4 1.3 GO:0030185 nitric oxide transport(GO:0030185) epithelial fluid transport(GO:0042045) regulation of saliva secretion(GO:0046877) positive regulation of saliva secretion(GO:0046878) cellular response to copper ion(GO:0071280)
0.4 3.4 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.4 11.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.4 3.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.4 2.8 GO:0015862 uridine transport(GO:0015862)
0.4 1.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.3 9.7 GO:0051963 regulation of synapse assembly(GO:0051963)
0.3 12.4 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.3 1.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732) cytoplasmic translation(GO:0002181) cytoplasmic translational initiation(GO:0002183)
0.3 1.9 GO:0032472 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472) manganese ion homeostasis(GO:0055071)
0.2 9.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.2 2.8 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 4.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.2 4.9 GO:0008272 sulfate transport(GO:0008272)
0.2 9.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.2 86.1 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.2 21.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.2 7.0 GO:0006309 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.1 4.0 GO:0035329 hippo signaling(GO:0035329)
0.1 6.7 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.1 1.5 GO:0006573 valine metabolic process(GO:0006573)
0.1 1.0 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 1.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 2.9 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.1 6.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114) negative regulation of protein depolymerization(GO:1901880)
0.1 29.3 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658) establishment of RNA localization(GO:0051236)
0.1 2.8 GO:0048265 response to pain(GO:0048265)
0.1 3.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 2.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 3.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 1.0 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 1.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.1 1.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 2.1 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 1.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.2 GO:0046415 urate metabolic process(GO:0046415)
0.1 10.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 6.8 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 0.3 GO:0090343 positive regulation of cell aging(GO:0090343)
0.1 34.0 GO:0016567 protein ubiquitination(GO:0016567)
0.0 1.4 GO:0006094 gluconeogenesis(GO:0006094)
0.0 4.4 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.4 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.7 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 21.3 GO:0006091 generation of precursor metabolites and energy(GO:0006091)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 3.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 6.8 GO:0007018 microtubule-based movement(GO:0007018)
0.0 8.4 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 2.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.7 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.5 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516) cerebellar cortex morphogenesis(GO:0021696)
0.0 2.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.8 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0006006 glucose metabolic process(GO:0006006)
0.0 2.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0019233 sensory perception of pain(GO:0019233)
0.0 2.2 GO:0007507 heart development(GO:0007507)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
33.4 100.1 GO:0005927 muscle tendon junction(GO:0005927)
18.3 54.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
14.6 58.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
9.8 236.0 GO:0005861 troponin complex(GO:0005861)
8.8 87.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
8.6 180.1 GO:0032982 myosin filament(GO:0032982)
7.2 28.7 GO:0032591 dendritic spine membrane(GO:0032591)
5.8 98.6 GO:0005859 muscle myosin complex(GO:0005859)
5.3 208.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
4.5 77.2 GO:0005916 fascia adherens(GO:0005916)
4.3 56.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
4.0 28.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
3.9 275.5 GO:0030018 Z disc(GO:0030018)
3.6 53.9 GO:0031143 pseudopodium(GO:0031143)
3.3 26.3 GO:0031674 I band(GO:0031674)
2.3 20.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
2.2 30.3 GO:0016461 unconventional myosin complex(GO:0016461)
1.4 14.3 GO:0016012 sarcoglycan complex(GO:0016012)
1.3 27.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.2 96.9 GO:0030017 sarcomere(GO:0030017)
0.9 6.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.6 1.3 GO:0043230 extracellular organelle(GO:0043230)
0.6 2.5 GO:0031592 centrosomal corona(GO:0031592)
0.6 11.7 GO:0016528 sarcoplasm(GO:0016528)
0.5 3.6 GO:0016589 NURF complex(GO:0016589)
0.5 12.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.4 47.5 GO:0034707 chloride channel complex(GO:0034707)
0.4 11.5 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.8 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.3 0.8 GO:0000802 transverse filament(GO:0000802)
0.3 14.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.3 10.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.3 3.3 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.3 5.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 3.0 GO:0030673 axolemma(GO:0030673)
0.2 2.8 GO:0042597 NMDA selective glutamate receptor complex(GO:0017146) outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.2 8.6 GO:0030016 myofibril(GO:0030016)
0.2 1.3 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.2 53.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 1.7 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.2 44.1 GO:0031225 anchored component of membrane(GO:0031225)
0.1 57.2 GO:0005813 centrosome(GO:0005813)
0.1 20.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.8 GO:0005922 connexon complex(GO:0005922)
0.1 6.8 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 11.2 GO:0005802 trans-Golgi network(GO:0005802)
0.1 7.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.7 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 36.6 GO:0005874 microtubule(GO:0005874)
0.1 7.3 GO:0042383 sarcolemma(GO:0042383)
0.1 2.6 GO:0031526 brush border membrane(GO:0031526)
0.1 5.5 GO:0070469 respiratory chain(GO:0070469)
0.1 2.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 6.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.5 GO:0044306 neuron projection terminus(GO:0044306)
0.0 23.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.7 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.4 GO:0005643 nuclear pore(GO:0005643)
0.0 12.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 42.3 GO:0005856 cytoskeleton(GO:0005856)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 15.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.4 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 1.1 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 7.2 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
14.2 156.3 GO:0031432 titin binding(GO:0031432)
10.7 107.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
10.2 71.4 GO:0032036 myosin heavy chain binding(GO:0032036)
10.1 100.7 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
7.0 28.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
7.0 20.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
6.1 24.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
6.0 84.4 GO:0031014 troponin T binding(GO:0031014)
4.0 32.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
3.8 15.2 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
3.7 11.0 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
3.4 17.0 GO:0004126 cytidine deaminase activity(GO:0004126)
3.4 88.3 GO:0005523 tropomyosin binding(GO:0005523)
2.9 11.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
2.9 34.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.3 23.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
2.3 50.8 GO:0005344 oxygen transporter activity(GO:0005344)
2.3 20.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
2.2 13.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
2.2 243.4 GO:0008307 structural constituent of muscle(GO:0008307)
2.1 33.6 GO:0030346 protein phosphatase 2B binding(GO:0030346)
1.8 18.0 GO:0050682 AF-2 domain binding(GO:0050682)
1.7 60.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.7 6.8 GO:0015254 glycerol channel activity(GO:0015254)
1.6 9.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.3 3.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.2 18.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
1.2 12.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
1.2 9.7 GO:0042805 actinin binding(GO:0042805)
1.2 27.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.1 17.4 GO:0044548 S100 protein binding(GO:0044548)
1.1 5.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
1.1 5.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
1.0 1.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.9 6.6 GO:0004689 glucan 1,4-alpha-glucosidase activity(GO:0004339) phosphorylase kinase activity(GO:0004689)
0.9 2.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.9 11.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.9 26.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.8 5.6 GO:0035326 enhancer binding(GO:0035326)
0.7 14.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H3-K9 specific)(GO:0032129) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.7 10.5 GO:0008242 omega peptidase activity(GO:0008242)
0.6 16.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.6 28.8 GO:0045296 cadherin binding(GO:0045296)
0.6 4.9 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.6 2.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.6 4.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.5 3.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 9.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 10.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 1.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.4 3.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 9.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.4 2.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 5.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.4 6.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.3 4.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.3 12.5 GO:0070888 E-box binding(GO:0070888)
0.3 2.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 210.2 GO:0003779 actin binding(GO:0003779)
0.3 1.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.3 2.5 GO:0043515 kinetochore binding(GO:0043515)
0.3 3.6 GO:0031491 nucleosome binding(GO:0031491)
0.3 7.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 4.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.3 1.9 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.3 12.0 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 14.9 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.2 1.6 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 0.6 GO:0031013 troponin I binding(GO:0031013)
0.2 5.3 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 76.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 21.3 GO:0005254 chloride channel activity(GO:0005254)
0.2 1.9 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.2 1.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 44.1 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 2.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.2 2.8 GO:0017166 vinculin binding(GO:0017166)
0.2 8.7 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 26.2 GO:0005516 calmodulin binding(GO:0005516)
0.1 4.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 3.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 9.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 5.7 GO:0050681 androgen receptor binding(GO:0050681)
0.1 8.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.0 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 6.8 GO:0005518 collagen binding(GO:0005518)
0.1 2.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 22.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 3.9 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 68.5 GO:0005102 receptor binding(GO:0005102)
0.0 7.4 GO:0003774 motor activity(GO:0003774)
0.0 2.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 4.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 6.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 5.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.9 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.4 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 1.7 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 2.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.5 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.1 20.3 ST_INTEGRIN_SIGNALING_PATHWAY Integrin Signaling Pathway
0.1 6.2 ST_FAS_SIGNALING_PATHWAY Fas Signaling Pathway
0.1 1.7 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.1 2.1 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.