Motif ID: MIXL1_GSX1_BSX_MEOX2_LHX4

Z-value: 1.704


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX4hg19_v2_chr1_+_180199393_180199426-0.476.2e-03Click!
GSX1hg19_v2_chr13_+_28366780_28366780-0.383.0e-02Click!
BSXhg19_v2_chr11_-_122852428_122852549-0.374.0e-02Click!
MEOX2hg19_v2_chr7_-_15726296_15726437-0.327.5e-02Click!
MIXL1hg19_v2_chr1_+_226411319_226411366-0.193.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of MIXL1_GSX1_BSX_MEOX2_LHX4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_36245561 8.363 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_32157947 7.756 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr13_-_46716969 7.330 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_108541545 6.587 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr14_+_22337014 6.546 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chrX_+_135730297 6.460 ENST00000370629.2
CD40LG
CD40 ligand
chr12_+_8666126 6.004 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr3_+_108541608 5.497 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr15_+_58430368 5.126 ENST00000558772.1
ENST00000219919.4
AQP9

aquaporin 9

chr2_-_158300556 5.054 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr14_+_22739823 4.899 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr15_+_58430567 4.840 ENST00000536493.1
AQP9
aquaporin 9
chr4_+_40198527 4.740 ENST00000381799.5
RHOH
ras homolog family member H
chr7_+_142378566 4.708 ENST00000390398.3
TRBV25-1
T cell receptor beta variable 25-1
chr2_+_169926047 4.679 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr11_-_2323089 4.646 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr5_+_66300464 4.623 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr2_-_89161432 4.587 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr7_+_80255472 4.470 ENST00000428497.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_+_90248739 4.334 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr2_+_7865923 4.266 ENST00000417930.1
AC092580.4
AC092580.4
chr12_+_10124110 4.249 ENST00000350667.4
CLEC12A
C-type lectin domain family 12, member A
chr13_-_41593425 4.242 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr1_-_183538319 4.123 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chrX_-_21676442 4.072 ENST00000379499.2
KLHL34
kelch-like family member 34
chr1_+_101003687 3.989 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr7_+_50348268 3.874 ENST00000438033.1
ENST00000439701.1
IKZF1

IKAROS family zinc finger 1 (Ikaros)

chr7_-_92777606 3.869 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr14_+_22564294 3.839 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr14_+_22992573 3.672 ENST00000390516.1
TRAJ21
T cell receptor alpha joining 21
chr6_-_32908792 3.634 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_116866773 3.633 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr13_-_99910673 3.582 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chrX_+_135730373 3.458 ENST00000370628.2
CD40LG
CD40 ligand
chr7_+_77428066 3.387 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr12_-_10151773 3.323 ENST00000298527.6
ENST00000348658.4
CLEC1B

C-type lectin domain family 1, member B

chr1_+_174844645 3.308 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_139613269 3.306 ENST00000358430.3
TXLNB
taxilin beta
chr17_-_57229155 3.301 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr14_+_22631122 3.230 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr7_+_37723336 3.218 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr1_-_92952433 3.216 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr4_+_40201954 3.088 ENST00000511121.1
RHOH
ras homolog family member H
chr1_-_150738261 3.030 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr16_-_4852915 2.969 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr15_+_75080883 2.956 ENST00000567571.1
CSK
c-src tyrosine kinase
chr12_+_28410128 2.876 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr3_-_39321512 2.824 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr18_-_3220106 2.801 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr5_+_137722255 2.777 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr3_-_27764190 2.774 ENST00000537516.1
EOMES
eomesodermin
chr2_+_204571375 2.772 ENST00000374478.4
CD28
CD28 molecule
chrX_-_19817869 2.744 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr18_+_32556892 2.739 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2



microtubule-associated protein, RP/EB family, member 2



chr6_-_66417107 2.699 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr7_+_77428149 2.688 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr17_-_9694614 2.673 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr4_+_36283213 2.662 ENST00000357504.3
DTHD1
death domain containing 1
chr17_-_38956205 2.614 ENST00000306658.7
KRT28
keratin 28
chr14_+_92789498 2.613 ENST00000531433.1
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr2_-_145277569 2.579 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr18_-_3219847 2.578 ENST00000261606.7
MYOM1
myomesin 1
chr1_+_154401791 2.571 ENST00000476006.1
IL6R
interleukin 6 receptor
chr7_+_18329712 2.557 ENST00000433709.2
HDAC9
histone deacetylase 9
chr2_-_61697862 2.552 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr1_+_62439037 2.479 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr2_-_145188137 2.470 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr14_+_22947861 2.468 ENST00000390482.1
TRAJ57
T cell receptor alpha joining 57
chr6_-_32908765 2.464 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chrX_+_123097014 2.409 ENST00000394478.1
STAG2
stromal antigen 2
chr5_+_66300446 2.409 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_+_50016610 2.405 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_+_117544366 2.388 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr2_+_68962014 2.383 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr15_+_86087267 2.365 ENST00000558166.1
AKAP13
A kinase (PRKA) anchor protein 13
chr2_-_214016314 2.364 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr18_-_44181442 2.319 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr6_+_53964336 2.318 ENST00000447836.2
ENST00000511678.1
MLIP

muscular LMNA-interacting protein

chr11_-_111649015 2.304 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr13_+_78315466 2.297 ENST00000314070.5
ENST00000462234.1
SLAIN1

SLAIN motif family, member 1

chr2_+_90273679 2.294 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr2_+_68961934 2.293 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chrX_-_15332665 2.279 ENST00000537676.1
ENST00000344384.4
ASB11

ankyrin repeat and SOCS box containing 11

chr11_-_33913708 2.270 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_-_104972158 2.269 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr16_+_53133070 2.259 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_77427676 2.244 ENST00000257663.3
TMEM60
transmembrane protein 60
chr7_-_28220354 2.239 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr6_+_26365443 2.238 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2





butyrophilin, subfamily 3, member A2





chr14_+_22931924 2.231 ENST00000390477.2
TRDC
T cell receptor delta constant
chr3_+_121774202 2.225 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr5_-_142780280 2.225 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_-_33686925 2.216 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr2_+_68961905 2.179 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr2_-_179659669 2.151 ENST00000436599.1
TTN
titin
chr2_+_17997763 2.150 ENST00000281047.3
MSGN1
mesogenin 1
chr4_+_169013666 2.142 ENST00000359299.3
ANXA10
annexin A10
chr7_+_115862858 2.137 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr21_-_32253874 2.136 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr1_+_111415757 2.126 ENST00000429072.2
ENST00000271324.5
CD53

CD53 molecule

chr13_-_99910620 2.105 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr2_-_89160770 2.094 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr1_-_232651312 2.070 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr4_-_70653673 2.064 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr14_+_22465771 2.048 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr1_+_198607801 2.035 ENST00000367379.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_-_39191107 2.031 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr3_-_69129501 2.012 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3



ubiquitin-like modifier activating enzyme 3



chr10_-_104866395 2.008 ENST00000458345.1
NT5C2
5'-nucleotidase, cytosolic II
chr4_-_48116540 2.005 ENST00000506073.1
TXK
TXK tyrosine kinase
chr13_+_78315348 1.997 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr17_-_72527605 1.977 ENST00000392621.1
ENST00000314401.3
CD300LB

CD300 molecule-like family member b

chr11_+_35222629 1.967 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr6_-_130182410 1.947 ENST00000368143.1
TMEM244
transmembrane protein 244
chr2_+_90211643 1.946 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr11_-_104905840 1.927 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr6_+_130339710 1.924 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr2_-_89161064 1.908 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr12_-_114841703 1.906 ENST00000526441.1
TBX5
T-box 5
chr14_+_23001452 1.901 ENST00000390526.1
TRAJ11
T cell receptor alpha joining 11
chr10_+_126630692 1.887 ENST00000359653.4
ZRANB1
zinc finger, RAN-binding domain containing 1
chr3_-_33686743 1.881 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr5_+_54398463 1.878 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr5_+_53751445 1.873 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr2_+_190541153 1.840 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR



ankyrin and armadillo repeat containing



chr14_+_22670455 1.833 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr10_-_92681033 1.828 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_-_109605663 1.820 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr10_+_69865866 1.815 ENST00000354393.2
MYPN
myopalladin
chr10_-_21186144 1.808 ENST00000377119.1
NEBL
nebulette
chrY_+_14958970 1.799 ENST00000453031.1
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr6_-_116833500 1.794 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr10_+_94451574 1.777 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr3_-_191000172 1.776 ENST00000427544.2
UTS2B
urotensin 2B
chr1_-_157746909 1.772 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
FCRL2


Fc receptor-like 2


chr13_+_78315528 1.736 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr4_-_182186182 1.727 ENST00000512547.1
RP11-665C14.2
RP11-665C14.2
chr5_+_137673200 1.713 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr2_-_40680578 1.701 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_+_22748980 1.697 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr12_-_56694083 1.681 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
CS








citrate synthase








chr10_-_36812323 1.676 ENST00000543053.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr18_+_32173276 1.670 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA








dystrobrevin, alpha








chr17_-_39203519 1.655 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr1_-_25291475 1.648 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr10_-_33405600 1.623 ENST00000414308.1
RP11-342D11.3
RP11-342D11.3
chr11_+_59824060 1.618 ENST00000395032.2
ENST00000358152.2
MS4A3

membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)

chr2_+_149402989 1.613 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_25042231 1.607 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr7_+_80253387 1.599 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chrX_+_37639302 1.595 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chrX_+_107288280 1.595 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr20_+_42523336 1.592 ENST00000428529.1
RP5-1030M6.3
RP5-1030M6.3
chr5_-_39219641 1.592 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB



FYN binding protein



chr15_+_80351910 1.591 ENST00000261749.6
ENST00000561060.1
ZFAND6

zinc finger, AN1-type domain 6

chr2_-_89327228 1.589 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr4_-_120243545 1.587 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr12_+_64798826 1.583 ENST00000540203.1
XPOT
exportin, tRNA
chr1_+_74701062 1.580 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr13_+_78315295 1.574 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr14_+_22615942 1.573 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr4_+_26324474 1.559 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_39944025 1.550 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1


RP11-111A21.1


chr14_+_22180536 1.545 ENST00000390424.2
TRAV2
T cell receptor alpha variable 2
chr1_+_81106951 1.539 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr14_+_22987424 1.526 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr6_+_26199737 1.513 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr8_+_28748765 1.510 ENST00000355231.5
HMBOX1
homeobox containing 1
chr3_-_18480173 1.496 ENST00000414509.1
SATB1
SATB homeobox 1
chr3_-_18480260 1.494 ENST00000454909.2
SATB1
SATB homeobox 1
chr4_-_89442940 1.487 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr5_-_150473127 1.485 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr8_+_42873548 1.474 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr18_+_61554932 1.464 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr20_-_7238861 1.463 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr3_-_178103144 1.461 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1



RP11-33A14.1



chr12_-_10605929 1.449 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr3_-_141747950 1.448 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_71384257 1.443 ENST00000339336.4
AMTN
amelotin
chr11_+_59824127 1.423 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr3_+_186692745 1.421 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_-_9933500 1.419 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr6_-_32784687 1.402 ENST00000447394.1
ENST00000438763.2
HLA-DOB

major histocompatibility complex, class II, DO beta

chr2_+_204571198 1.396 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28


CD28 molecule


chr12_-_56693758 1.395 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
CS



citrate synthase



chr14_+_22433675 1.392 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr15_-_98836406 1.389 ENST00000560360.1
CTD-2544M6.1
CTD-2544M6.1
chr12_+_56325231 1.383 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr14_+_61654271 1.376 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH


protein kinase C, eta


chr9_+_12693336 1.374 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr19_-_46088068 1.368 ENST00000263275.4
ENST00000323060.3
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr5_-_147286065 1.368 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr4_-_89205705 1.363 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
PPM1K


protein phosphatase, Mg2+/Mn2+ dependent, 1K


chr14_+_32798547 1.362 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr2_+_152214098 1.358 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr17_-_38911580 1.348 ENST00000312150.4
KRT25
keratin 25
chr12_+_93096619 1.348 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr11_+_59856130 1.337 ENST00000278888.3
MS4A2
membrane-spanning 4-domains, subfamily A, member 2
chr7_+_107110488 1.336 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr4_-_76928641 1.336 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
2.5 9.9 GO:1904037 positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
2.0 10.0 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855)
1.0 3.0 GO:0001879 detection of yeast(GO:0001879)
0.9 4.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 4.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.8 2.4 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.7 2.2 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.6 2.6 GO:0002384 hepatic immune response(GO:0002384)
0.6 1.9 GO:0003218 cardiac left ventricle formation(GO:0003218) cell migration involved in heart development(GO:0060973)
0.6 1.9 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.6 3.9 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.5 3.8 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
0.5 6.6 GO:0060100 regulation of phagocytosis, engulfment(GO:0060099) positive regulation of phagocytosis, engulfment(GO:0060100) regulation of membrane invagination(GO:1905153) positive regulation of membrane invagination(GO:1905155)
0.5 1.5 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.5 4.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.5 3.2 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.4 1.8 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.4 3.6 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.4 3.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.4 1.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.4 1.5 GO:0071539 Golgi localization(GO:0051645) protein localization to centrosome(GO:0071539)
0.4 1.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.7 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.3 2.4 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.3 0.7 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.3 2.6 GO:0002431 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 5.3 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.3 1.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.3 4.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.3 2.2 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.3 0.8 GO:0051126 negative regulation of actin nucleation(GO:0051126)
0.3 7.7 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.3 4.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.2 2.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 1.7 GO:0071436 sodium ion export(GO:0071436)
0.2 1.8 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.2 2.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.2 0.7 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.2 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.2 0.4 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 1.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.2 7.4 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.2 0.6 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.2 0.8 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.2 0.6 GO:0001692 histamine metabolic process(GO:0001692)
0.2 4.1 GO:0034453 microtubule anchoring(GO:0034453)
0.2 1.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.8 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 0.6 GO:1902414 protein localization to adherens junction(GO:0071896) protein localization to cell junction(GO:1902414)
0.2 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 0.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2 1.8 GO:0045116 protein neddylation(GO:0045116)
0.2 1.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 0.5 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.2 0.5 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2 0.7 GO:0045204 MAPK export from nucleus(GO:0045204) MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 0.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.2 1.0 GO:1902224 cellular ketone body metabolic process(GO:0046950) ketone body catabolic process(GO:0046952) ketone body metabolic process(GO:1902224)
0.2 7.3 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.2 2.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 2.4 GO:0032876 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2 2.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 1.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 1.0 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.4 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047) negative regulation of protein phosphatase type 2A activity(GO:0034048)
0.1 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 1.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 3.9 GO:0000090 mitotic anaphase(GO:0000090)
0.1 0.8 GO:0034959 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.1 1.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.5 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 1.3 GO:0045109 intermediate filament organization(GO:0045109)
0.1 6.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.3 GO:0042693 muscle cell fate commitment(GO:0042693)
0.1 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.1 0.6 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 1.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1 7.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.5 GO:0007620 copulation(GO:0007620)
0.1 0.6 GO:0007368 determination of left/right symmetry(GO:0007368) determination of bilateral symmetry(GO:0009855)
0.1 1.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0046056 dADP biosynthetic process(GO:0006173) purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183) dADP metabolic process(GO:0046056)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 2.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 1.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.1 0.4 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.4 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.8 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 1.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 1.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 1.6 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 1.5 GO:0007379 segment specification(GO:0007379)
0.1 2.3 GO:0051923 sulfation(GO:0051923)
0.1 3.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.1 2.3 GO:0006906 vesicle fusion(GO:0006906)
0.1 0.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.9 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.1 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:2000645 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) negative regulation of receptor catabolic process(GO:2000645)
0.1 0.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 1.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.1 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.3 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.7 GO:0032098 regulation of appetite(GO:0032098)
0.1 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.3 GO:0048305 immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.1 1.6 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.1 0.6 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.1 GO:0051929 obsolete positive regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051929)
0.1 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.0 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.1 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.5 GO:0045730 respiratory burst(GO:0045730)
0.1 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.9 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 3.5 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 1.9 GO:0006555 methionine metabolic process(GO:0006555)
0.1 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 0.3 GO:0006848 pyruvate transport(GO:0006848)
0.1 4.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.6 GO:0008347 glial cell migration(GO:0008347)
0.1 1.4 GO:0001556 oocyte maturation(GO:0001556)
0.1 0.3 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.1 1.1 GO:0098543 detection of other organism(GO:0098543)
0.1 0.3 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.1 2.8 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.1 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.1 0.3 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.3 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.6 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1 0.2 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410)
0.1 6.6 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.2 GO:0051311 meiotic metaphase I plate congression(GO:0043060) spindle midzone assembly(GO:0051255) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 1.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.2 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.1 4.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.1 1.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.1 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.6 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.2 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 2.2 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.5 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.4 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 11.9 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 2.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 2.2 GO:0006195 purine nucleotide catabolic process(GO:0006195)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.5 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.4 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0030952 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.3 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.4 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.8 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.2 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.6 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.6 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 1.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.0 2.3 GO:0030097 hemopoiesis(GO:0030097)
0.0 0.2 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 1.8 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0010727 regulation of hydrogen peroxide metabolic process(GO:0010310) negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 1.3 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 2.8 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.3 GO:0045008 depyrimidination(GO:0045008)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.7 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 2.3 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.1 GO:1903306 platelet aggregation(GO:0070527) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.6 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.7 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 2.5 GO:0000910 cytokinesis(GO:0000910)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.7 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0032196 transposition, DNA-mediated(GO:0006313) transposition(GO:0032196)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.2 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.8 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.4 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:1904358 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.2 GO:0046638 regulation of alpha-beta T cell differentiation(GO:0046637) positive regulation of alpha-beta T cell differentiation(GO:0046638)
0.0 0.2 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.0 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.8 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 2.8 GO:0042113 B cell activation(GO:0042113)
0.0 0.5 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 1.0 GO:0006644 phospholipid metabolic process(GO:0006644)
0.0 1.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.8 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 13.3 GO:0016568 chromatin modification(GO:0016568)
0.0 0.6 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 1.5 GO:0006260 DNA replication(GO:0006260)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.4 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.8 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 2.2 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.9 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0008154 actin polymerization or depolymerization(GO:0008154)
0.0 0.6 GO:0001824 blastocyst development(GO:0001824)
0.0 0.2 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 0.4 GO:0050931 melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931) neuroepithelial cell differentiation(GO:0060563)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0031669 cellular response to nutrient levels(GO:0031669)
0.0 1.0 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0051103 V(D)J recombination(GO:0033151) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.7 GO:0007569 cell aging(GO:0007569)
0.0 0.2 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011) UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.7 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.6 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 2.1 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0009791 post-embryonic development(GO:0009791)
0.0 1.1 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 1.3 GO:0071426 ribonucleoprotein complex export from nucleus(GO:0071426)
0.0 1.0 GO:0007623 circadian rhythm(GO:0007623)
0.0 4.7 GO:0007067 mitotic nuclear division(GO:0007067)
0.0 0.3 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 0.4 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.4 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.6 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.4 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 1.8 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 0.1 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0000236 mitotic prometaphase(GO:0000236)
0.0 0.1 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.3 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.1 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.1 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082)
0.0 2.3 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 3.4 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.7 GO:0007162 negative regulation of cell adhesion(GO:0007162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.6 13.5 GO:0042101 T cell receptor complex(GO:0042101)
0.5 2.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.5 8.1 GO:0001891 phagocytic cup(GO:0001891)
0.4 5.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 7.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 4.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 4.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.3 0.9 GO:0036452 ESCRT III complex(GO:0000815) ESCRT complex(GO:0036452)
0.3 6.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 1.2 GO:0000267 obsolete cell fraction(GO:0000267)
0.2 3.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 1.6 GO:0045179 apical cortex(GO:0045179)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 2.4 GO:0031430 M band(GO:0031430)
0.2 0.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.2 0.8 GO:0060171 stereocilium membrane(GO:0060171)
0.2 1.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) beta-catenin-TCF complex(GO:1990907)
0.1 1.5 GO:0030018 Z disc(GO:0030018)
0.1 1.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.8 GO:0070695 FHF complex(GO:0070695)
0.1 1.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0061645 actin cortical patch(GO:0030479) endocytic patch(GO:0061645)
0.1 1.5 GO:0070688 MLL5-L complex(GO:0070688)
0.1 2.6 GO:0042611 MHC protein complex(GO:0042611)
0.1 6.5 GO:0045095 keratin filament(GO:0045095)
0.1 0.6 GO:0005827 polar microtubule(GO:0005827)
0.1 1.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 1.9 GO:0016235 aggresome(GO:0016235)
0.1 0.3 GO:0005884 actin filament(GO:0005884)
0.1 0.4 GO:0070852 cell body fiber(GO:0070852)
0.1 0.6 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.8 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 4.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 1.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 1.9 GO:0001772 immunological synapse(GO:0001772)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 3.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 1.3 GO:0030315 T-tubule(GO:0030315)
0.0 5.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 1.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0005712 chiasma(GO:0005712) MutLbeta complex(GO:0032390)
0.0 10.6 GO:0005769 early endosome(GO:0005769)
0.0 0.5 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 2.4 GO:0034774 platelet alpha granule lumen(GO:0031093) vesicle lumen(GO:0031983) secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 1.4 GO:0019861 obsolete flagellum(GO:0019861)
0.0 1.0 GO:0043205 fibril(GO:0043205)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 8.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.0 3.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 2.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 3.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0045120 pronucleus(GO:0045120)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0097651 phosphatidylinositol 3-kinase complex, class IA(GO:0005943) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.1 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 4.7 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 4.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 4.9 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 1.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0030017 sarcomere(GO:0030017)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 10.6 GO:0005625 obsolete soluble fraction(GO:0005625)
0.0 1.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 32.7 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 2.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898) cytoplasmic side of membrane(GO:0098562)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.8 GO:0005813 centrosome(GO:0005813)
0.0 0.9 GO:0034399 nuclear periphery(GO:0034399)
0.0 4.1 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 35.1 GO:0005829 cytosol(GO:0005829)
0.0 3.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.1 GO:0030141 secretory granule(GO:0030141)
0.0 0.6 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.9 GO:0005174 CD40 receptor binding(GO:0005174)
2.5 10.0 GO:0015254 glycerol channel activity(GO:0015254)
1.4 4.3 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
1.3 12.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.0 3.0 GO:0001874 polysaccharide receptor activity(GO:0001873) (1->3)-beta-D-glucan receptor activity(GO:0001874)
0.9 2.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.7 3.7 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.6 1.8 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.6 6.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.6 2.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.5 4.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.5 2.4 GO:0031433 telethonin binding(GO:0031433)
0.4 1.3 GO:0019767 IgE receptor activity(GO:0019767)
0.4 1.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 5.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.4 3.8 GO:0031489 myosin V binding(GO:0031489)
0.4 1.8 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 2.1 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.3 2.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 0.9 GO:0016826 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.3 4.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.3 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 2.0 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 7.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 2.2 GO:0004883 glucocorticoid receptor activity(GO:0004883)
0.2 1.9 GO:0000150 recombinase activity(GO:0000150)
0.2 1.9 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 7.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.9 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.2 1.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.2 1.5 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.2 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 4.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.1 GO:0003680 AT DNA binding(GO:0003680)
0.2 3.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.7 GO:0008410 3-oxoacid CoA-transferase activity(GO:0008260) CoA-transferase activity(GO:0008410)
0.2 2.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.8 GO:0016530 metallochaperone activity(GO:0016530)
0.2 6.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 2.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.5 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 6.2 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.8 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.6 GO:0031013 troponin I binding(GO:0031013)
0.1 1.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.8 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987) Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.1 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.6 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 1.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 1.0 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 4.0 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.4 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.9 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 1.0 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 1.6 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.3 GO:0035671 enone reductase activity(GO:0035671) 3-oxo-5-beta-steroid 4-dehydrogenase activity(GO:0047568) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 4.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.7 GO:0015368 calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.1 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lipopolysaccharide N-acetylglucosaminyltransferase activity(GO:0008917)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 3.5 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 1.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) RNA polymerase II basal transcription factor binding(GO:0001091) TFIIB-class transcription factor binding(GO:0001093)
0.1 2.0 GO:0051018 protein kinase A binding(GO:0051018)
0.1 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 3.0 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.1 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 0.5 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 1.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.3 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0050833 pyruvate secondary active transmembrane transporter activity(GO:0005477) pyruvate transmembrane transporter activity(GO:0050833)
0.1 4.4 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 7.5 GO:0051015 actin filament binding(GO:0051015)
0.1 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 6.3 GO:0046332 SMAD binding(GO:0046332)
0.1 9.6 GO:0008017 microtubule binding(GO:0008017)
0.1 0.2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.0 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 4.3 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.2 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 4.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.6 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.9 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 16.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.5 GO:0000049 tRNA binding(GO:0000049)
0.0 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.5 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 1.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.0 2.0 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 11.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.6 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 1.0 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 2.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 7.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 2.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0003917 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0 2.8 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 1.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 3.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 10.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 1.2 GO:0010843 obsolete promoter binding(GO:0010843)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 3.4 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 2.3 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.0 0.3 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.2 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.6 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.5 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.1 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.1 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 14.6 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.1 2.6 ST_STAT3_PATHWAY STAT3 Pathway
0.1 2.1 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.1 4.0 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.0 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.5 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.2 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.6 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.3 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.5 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.