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Illumina Body Map 2: averaged replicates

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Results for MSX1

Z-value: 1.81

Motif logo

Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
ENSG00000163132.6 msh homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX1hg19_v2_chr4_+_4861385_48613980.173.6e-01Click!

Activity profile of MSX1 motif

Sorted Z-values of MSX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_121647386 4.13 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
synuclein, alpha interacting protein
chr6_+_6588316 2.97 ENST00000379953.2
lymphocyte antigen 86
chr2_-_158345462 2.31 ENST00000439355.1
ENST00000540637.1
cytohesin 1 interacting protein
chr3_-_123339343 2.12 ENST00000578202.1
myosin light chain kinase
chr14_-_52066633 2.10 ENST00000557625.1
FRMD6 antisense RNA 2
chr8_+_24241789 2.09 ENST00000256412.4
ENST00000538205.1
ADAM-like, decysin 1
chr14_-_52066664 2.05 ENST00000556617.1
FRMD6 antisense RNA 2
chr8_+_24241969 1.93 ENST00000522298.1
ADAM-like, decysin 1
chr3_-_123339418 1.92 ENST00000583087.1
myosin light chain kinase
chr22_-_32766972 1.90 ENST00000382084.4
ENST00000382086.2
RFPL3 antisense
chr1_-_167487758 1.89 ENST00000362089.5
CD247 molecule
chr1_-_160492994 1.78 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAM family member 6
chr14_+_22631122 1.76 ENST00000390458.3
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr14_+_22293618 1.74 ENST00000390432.2
T cell receptor alpha variable 10
chr6_-_32784687 1.74 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr18_-_70532906 1.72 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr3_-_21792838 1.71 ENST00000281523.2
zinc finger protein 385D
chr15_-_95870310 1.70 ENST00000508732.2
CTD-2536I1.1
chr15_-_95870348 1.64 ENST00000556899.1
CTD-2536I1.1
chr22_-_32767017 1.61 ENST00000400234.1
RFPL3 antisense
chrX_-_14891150 1.61 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
Fanconi anemia, complementation group B
chrX_+_134654540 1.59 ENST00000370752.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr18_-_5396271 1.59 ENST00000579951.1
erythrocyte membrane protein band 4.1-like 3
chr8_-_71157595 1.57 ENST00000519724.1
nuclear receptor coactivator 2
chr6_-_109776901 1.56 ENST00000431946.1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr6_+_28249299 1.55 ENST00000405948.2
piggyBac transposable element derived 1
chrX_+_1710484 1.54 ENST00000313871.3
ENST00000381261.3
A kinase (PRKA) anchor protein 17A
chr9_+_44868935 1.53 ENST00000448436.2
RP11-160N1.10
chr6_-_84419101 1.44 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
synaptosomal-associated protein, 91kDa
chr11_+_115498761 1.43 ENST00000424313.2
AP000997.1
chr11_-_114430570 1.43 ENST00000251921.2
neurexophilin and PC-esterase domain family, member 1
chr12_+_54422142 1.42 ENST00000243108.4
homeobox C6
chr17_-_37934466 1.41 ENST00000583368.1
IKAROS family zinc finger 3 (Aiolos)
chr12_+_9980069 1.40 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
killer cell lectin-like receptor subfamily F, member 1
chr5_-_11588907 1.39 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr1_-_167487808 1.38 ENST00000392122.3
CD247 molecule
chr12_+_56324933 1.36 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr3_+_114012819 1.35 ENST00000383671.3
T cell immunoreceptor with Ig and ITIM domains
chr12_+_56324756 1.35 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chrX_-_142605301 1.33 ENST00000370503.2
SPANX family, member N3
chr19_-_7812446 1.32 ENST00000394173.4
ENST00000301357.8
CD209 molecule
chr12_-_10541575 1.32 ENST00000540818.1
killer cell lectin-like receptor subfamily K, member 1
chr11_+_101785727 1.30 ENST00000263468.8
KIAA1377
chr6_+_28249332 1.29 ENST00000259883.3
piggyBac transposable element derived 1
chr19_-_39805976 1.28 ENST00000248668.4
leucine rich repeat and fibronectin type III domain containing 1
chr7_-_36634181 1.25 ENST00000538464.1
acyloxyacyl hydrolase (neutrophil)
chr1_+_84630645 1.24 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_145278475 1.18 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr17_-_8113542 1.15 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr14_+_52327109 1.15 ENST00000335281.4
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_111415757 1.14 ENST00000429072.2
ENST00000271324.5
CD53 molecule
chr14_+_52327350 1.14 ENST00000555472.1
ENST00000556766.1
guanine nucleotide binding protein (G protein), gamma 2
chr6_-_109777128 1.13 ENST00000358807.3
ENST00000358577.3
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr14_+_55595762 1.11 ENST00000254301.9
lectin, galactoside-binding, soluble, 3
chr18_-_3874271 1.10 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
discs, large (Drosophila) homolog-associated protein 1
chr14_+_101295638 1.09 ENST00000523671.2
maternally expressed 3 (non-protein coding)
chr6_+_130339710 1.08 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr4_+_146601356 1.08 ENST00000438731.1
ENST00000511965.1
chromosome 4 open reading frame 51
chr19_-_7812397 1.07 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209 molecule
chr1_+_84630574 1.06 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_36450169 1.02 ENST00000428612.1
anillin, actin binding protein
chr11_+_7506584 1.01 ENST00000530135.1
olfactomedin-like 1
chr1_+_74701062 0.99 ENST00000326637.3
TNNI3 interacting kinase
chr2_-_158345341 0.98 ENST00000435117.1
cytohesin 1 interacting protein
chr7_-_105332084 0.98 ENST00000472195.1
ataxin 7-like 1
chr12_+_9980113 0.97 ENST00000537723.1
killer cell lectin-like receptor subfamily F, member 1
chr1_+_158985457 0.97 ENST00000567661.1
ENST00000474473.1
interferon, gamma-inducible protein 16
chr4_-_164534657 0.94 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_20256965 0.92 ENST00000400331.5
ENST00000332878.4
metastasis associated in colon cancer 1
chr14_-_92247032 0.90 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr14_+_22964877 0.84 ENST00000390494.1
T cell receptor alpha joining 43
chr11_+_62037622 0.84 ENST00000227918.2
ENST00000525380.1
secretoglobin, family 2A, member 2
chr3_-_123512688 0.82 ENST00000475616.1
myosin light chain kinase
chr4_-_120243545 0.81 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr1_+_44514040 0.80 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4
chr5_+_82767487 0.79 ENST00000343200.5
ENST00000342785.4
versican
chr11_-_66964638 0.78 ENST00000444002.2
AP001885.1
chr5_+_55354822 0.78 ENST00000511861.1
CTD-2227I18.1
chrX_+_69501943 0.78 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41, member RAS oncogene family
chr10_+_17270214 0.78 ENST00000544301.1
vimentin
chr14_+_31046959 0.76 ENST00000547532.1
ENST00000555429.1
G2/M-phase specific E3 ubiquitin protein ligase
chr14_+_55595960 0.69 ENST00000554715.1
lectin, galactoside-binding, soluble, 3
chr1_-_149908217 0.68 ENST00000369140.3
myotubularin related protein 11
chr2_+_202098203 0.68 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
caspase 8, apoptosis-related cysteine peptidase
chr19_-_53758094 0.67 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
zinc finger protein 677
chr2_+_196313239 0.66 ENST00000413290.1
AC064834.1
chr5_-_177207634 0.65 ENST00000513554.1
ENST00000440605.3
family with sequence similarity 153, member A
chr6_+_26240561 0.64 ENST00000377745.2
histone cluster 1, H4f
chr9_+_90112117 0.64 ENST00000358077.5
death-associated protein kinase 1
chr19_-_53757941 0.64 ENST00000594517.1
ENST00000601413.1
ENST00000594681.1
zinc finger protein 677
chr1_+_158815588 0.64 ENST00000438394.1
myeloid cell nuclear differentiation antigen
chr17_-_48785216 0.63 ENST00000285243.6
ankyrin repeat domain 40
chr17_-_42441204 0.62 ENST00000293443.7
family with sequence similarity 171, member A2
chr22_+_51176624 0.62 ENST00000216139.5
ENST00000529621.1
acrosin
chr11_+_92085262 0.61 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT atypical cadherin 3
chr1_-_72566613 0.61 ENST00000306821.3
neuronal growth regulator 1
chr8_-_25281747 0.60 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr2_-_109605663 0.60 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
ectodysplasin A receptor
chr10_+_135050908 0.59 ENST00000325980.9
VENT homeobox
chr15_+_51669513 0.59 ENST00000558426.1
gliomedin
chr7_-_142104553 0.58 ENST00000390379.1
T cell receptor beta variable 6-9
chr10_+_97709725 0.58 ENST00000472454.2
Protein LOC100652732
chr5_+_82767583 0.57 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
versican
chr5_+_82767284 0.55 ENST00000265077.3
versican
chr12_+_9066472 0.51 ENST00000538657.1
polyhomeotic homolog 1 (Drosophila)
chr1_-_2461684 0.51 ENST00000378453.3
hes family bHLH transcription factor 5
chr3_-_93781750 0.51 ENST00000314636.2
dihydrofolate reductase-like 1
chr9_-_23779367 0.51 ENST00000440102.1
ELAV like neuron-specific RNA binding protein 2
chr14_-_101295407 0.50 ENST00000596284.1
AL117190.2
chr1_+_224370873 0.49 ENST00000323699.4
ENST00000391877.3
delta(4)-desaturase, sphingolipid 1
chr12_+_82752647 0.48 ENST00000550058.1
methyltransferase like 25
chr6_+_136172820 0.47 ENST00000308191.6
phosphodiesterase 7B
chr9_-_15510287 0.46 ENST00000397519.2
PC4 and SFRS1 interacting protein 1
chr13_-_52733670 0.46 ENST00000550841.1
NIMA-related kinase 3
chr9_+_130026756 0.46 ENST00000314904.5
ENST00000373387.4
GTPase activating Rap/RanGAP domain-like 3
chr4_+_5527117 0.46 ENST00000505296.1
chromosome 4 open reading frame 6
chr9_+_75229616 0.45 ENST00000340019.3
transmembrane channel-like 1
chr19_-_45457264 0.44 ENST00000591646.1
Uncharacterized protein
chr7_-_32338917 0.44 ENST00000396193.1
phosphodiesterase 1C, calmodulin-dependent 70kDa
chrX_-_119149501 0.44 ENST00000454625.1
GS1-421I3.2
chr5_+_175490540 0.43 ENST00000515817.1
family with sequence similarity 153, member B
chr14_+_22987424 0.42 ENST00000390511.1
T cell receptor alpha joining 26
chr16_+_21689835 0.42 ENST00000286149.4
ENST00000388958.3
otoancorin
chr1_-_35450897 0.41 ENST00000373337.3
ZMYM6 neighbor
chr12_+_48592134 0.41 ENST00000595310.1
DKFZP779L1853
chr13_-_52733980 0.41 ENST00000339406.3
NIMA-related kinase 3
chr6_-_32557610 0.40 ENST00000360004.5
major histocompatibility complex, class II, DR beta 1
chr7_-_116607526 0.40 ENST00000420664.1
Uncharacterized protein
chr4_+_5526883 0.40 ENST00000195455.2
chromosome 4 open reading frame 6
chr19_-_53662257 0.38 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
zinc finger protein 347
chr8_-_99057742 0.38 ENST00000521291.1
ENST00000396070.2
ENST00000523172.1
ENST00000287038.3
ribosomal protein L30
chr6_+_134758827 0.38 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr8_+_117963190 0.37 ENST00000427715.2
solute carrier family 30 (zinc transporter), member 8
chr3_-_180397256 0.37 ENST00000442201.2
coiled-coil domain containing 39
chr1_-_20503917 0.36 ENST00000429261.2
phospholipase A2, group IIC
chr3_+_93781728 0.36 ENST00000314622.4
NOP2/Sun domain family, member 3
chr4_+_9446156 0.35 ENST00000334879.1
defensin, beta 131
chr1_-_114429997 0.35 ENST00000471267.1
ENST00000393320.3
BCL2-like 15
chr9_+_133539981 0.35 ENST00000253008.2
PR domain containing 12
chr7_-_16840820 0.32 ENST00000450569.1
anterior gradient 2
chr2_-_207583120 0.32 ENST00000452335.2
dystrotelin
chr14_+_22994472 0.32 ENST00000390519.1
T cell receptor alpha joining 18
chr6_+_28092338 0.32 ENST00000340487.4
zinc finger and SCAN domain containing 16
chr2_-_31361543 0.32 ENST00000349752.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr21_+_33671264 0.31 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr3_+_108308513 0.31 ENST00000361582.3
DAZ interacting zinc finger protein 3
chr13_-_47471155 0.31 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chrX_-_122756660 0.30 ENST00000441692.1
THO complex 2
chr4_+_119809984 0.30 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
synaptopodin 2
chr21_+_17792672 0.30 ENST00000602620.1
long intergenic non-protein coding RNA 478
chr18_+_29598335 0.29 ENST00000217740.3
ring finger protein 125, E3 ubiquitin protein ligase
chr9_+_67977438 0.28 ENST00000456982.1
Protein LOC644249
chr2_-_219031709 0.28 ENST00000295683.2
chemokine (C-X-C motif) receptor 1
chr16_-_71518504 0.28 ENST00000565100.2
zinc finger protein 19
chr11_+_60681346 0.28 ENST00000227525.3
transmembrane protein 109
chr3_+_171561127 0.28 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr2_-_136288113 0.28 ENST00000401392.1
zinc finger, RAN-binding domain containing 3
chr7_-_55620433 0.27 ENST00000418904.1
vesicular, overexpressed in cancer, prosurvival protein 1
chr15_-_77712477 0.27 ENST00000560626.2
pseudopodium-enriched atypical kinase 1
chr12_+_14561422 0.27 ENST00000541056.1
activating transcription factor 7 interacting protein
chr5_-_147162078 0.25 ENST00000507386.1
janus kinase and microtubule interacting protein 2
chrX_-_103499602 0.24 ENST00000372588.4
ESX homeobox 1
chr14_+_22997487 0.24 ENST00000390521.1
T cell receptor alpha joining 16
chr16_+_53412368 0.23 ENST00000565189.1
RP11-44F14.2
chr1_-_185597619 0.23 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
chr6_-_32908765 0.23 ENST00000416244.2
major histocompatibility complex, class II, DM beta
chr6_-_32095968 0.22 ENST00000375203.3
ENST00000375201.4
activating transcription factor 6 beta
chr11_-_114430588 0.22 ENST00000534921.1
neurexophilin and PC-esterase domain family, member 1
chr20_+_52824367 0.21 ENST00000371419.2
prefoldin subunit 4
chr14_+_22133297 0.21 ENST00000408935.1
olfactory receptor, family 4, subfamily E, member 2
chr14_-_73997901 0.21 ENST00000557603.1
ENST00000556455.1
HEAT repeat containing 4
chr18_-_3874247 0.19 ENST00000581699.1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_242498135 0.16 ENST00000318407.3
BCL2-related ovarian killer
chr1_-_158656386 0.16 ENST00000467387.1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_-_32667660 0.15 ENST00000375110.2
enhancer of polycomb homolog 1 (Drosophila)
chr2_-_77749387 0.14 ENST00000409884.1
leucine rich repeat transmembrane neuronal 4
chr11_+_59855724 0.14 ENST00000524868.1
membrane-spanning 4-domains, subfamily A, member 2
chr2_-_77749336 0.13 ENST00000409282.1
leucine rich repeat transmembrane neuronal 4
chr5_+_140762268 0.13 ENST00000518325.1
protocadherin gamma subfamily A, 7
chr13_-_86373536 0.13 ENST00000400286.2
SLIT and NTRK-like family, member 6
chrY_-_2655644 0.13 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
sex determining region Y
chr21_+_33671160 0.12 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr14_+_50291993 0.12 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr12_+_7864021 0.12 ENST00000345088.2
developmental pluripotency associated 3
chr15_+_77712993 0.11 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
high mobility group 20A
chr15_+_77713222 0.11 ENST00000558176.1
high mobility group 20A
chr11_-_92931098 0.11 ENST00000326402.4
solute carrier family 36 (proton/amino acid symporter), member 4
chr12_+_105380073 0.11 ENST00000552951.1
ENST00000280749.5
chromosome 12 open reading frame 45
chr2_-_77749474 0.11 ENST00000409093.1
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr3_+_108308559 0.10 ENST00000486815.1
DAZ interacting zinc finger protein 3
chr20_+_5731083 0.10 ENST00000445603.1
ENST00000442185.1
chromosome 20 open reading frame 196
chr15_+_51669444 0.09 ENST00000396399.2
gliomedin
chr1_+_202091980 0.09 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr20_+_5731027 0.09 ENST00000378979.4
ENST00000303142.6
chromosome 20 open reading frame 196
chr14_-_64194745 0.08 ENST00000247225.6
sphingosine-1-phosphate phosphatase 1
chr2_-_218621272 0.08 ENST00000423123.1
disrupted in renal carcinoma 3
chr17_-_30228678 0.08 ENST00000261708.4
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr1_-_226595741 0.07 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
poly (ADP-ribose) polymerase 1
chr14_+_55494323 0.07 ENST00000339298.2
suppressor of cytokine signaling 4
chr2_-_88927092 0.07 ENST00000303236.3
eukaryotic translation initiation factor 2-alpha kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.5 4.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.1 GO:0019417 sulfur oxidation(GO:0019417)
0.5 1.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.5 2.4 GO:0046968 peptide antigen transport(GO:0046968)
0.4 1.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.4 1.8 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.3 1.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.0 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.3 3.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 2.3 GO:0097338 response to clozapine(GO:0097338)
0.2 1.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.5 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.6 GO:1990637 response to prolactin(GO:1990637)
0.1 0.7 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 1.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 1.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 4.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 1.8 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 2.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.5 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.8 GO:0070307 Bergmann glial cell differentiation(GO:0060020) lens fiber cell development(GO:0070307)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 2.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.6 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 1.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 1.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:1904760 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 2.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.9 GO:0036128 CatSper complex(GO:0036128)
0.1 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 2.9 GO:0001772 immunological synapse(GO:0001772)
0.0 4.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 4.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0030055 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0015934 organellar ribosome(GO:0000313) organellar large ribosomal subunit(GO:0000315) mitochondrial ribosome(GO:0005761) mitochondrial large ribosomal subunit(GO:0005762) large ribosomal subunit(GO:0015934) ribosomal subunit(GO:0044391)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.6 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.4 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.3 1.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 2.4 GO:0046790 virion binding(GO:0046790)
0.2 1.9 GO:0019863 IgE binding(GO:0019863)
0.2 2.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.6 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 2.1 GO:0071949 FAD binding(GO:0071949)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 2.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 3.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 3.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1