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Illumina Body Map 2: averaged replicates

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Results for MSX1

Z-value: 1.81

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Transcription factors associated with MSX1

Gene Symbol Gene ID Gene Info
MSX1
ENSG00000163132.6 msh homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX1hg19_v2_chr4_+_4861385_48613980.173.6e-01Click!

Activity profile of MSX1 motif

Sorted Z-values of MSX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_121647386 4.13 ENST00000542191.1
ENST00000506272.1
ENST00000508681.1
ENST00000509154.2
SNCAIP
synuclein, alpha interacting protein
chr6_+_6588316 2.97 ENST00000379953.2
LY86
lymphocyte antigen 86
chr2_-_158345462 2.31 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr3_-_123339343 2.12 ENST00000578202.1
MYLK
myosin light chain kinase
chr14_-_52066633 2.10 ENST00000557625.1
FRMD6-AS2
FRMD6 antisense RNA 2
chr8_+_24241789 2.09 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr14_-_52066664 2.05 ENST00000556617.1
FRMD6-AS2
FRMD6 antisense RNA 2
chr8_+_24241969 1.93 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr3_-_123339418 1.92 ENST00000583087.1
MYLK
myosin light chain kinase
chr22_-_32766972 1.90 ENST00000382084.4
ENST00000382086.2
RFPL3S
RFPL3 antisense
chr1_-_167487758 1.89 ENST00000362089.5
CD247
CD247 molecule
chr1_-_160492994 1.78 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr14_+_22631122 1.76 ENST00000390458.3
TRAV29DV5
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr14_+_22293618 1.74 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr6_-_32784687 1.74 ENST00000447394.1
ENST00000438763.2
HLA-DOB
major histocompatibility complex, class II, DO beta
chr18_-_70532906 1.72 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr3_-_21792838 1.71 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr15_-_95870310 1.70 ENST00000508732.2
CTD-2536I1.1
CTD-2536I1.1
chr15_-_95870348 1.64 ENST00000556899.1
CTD-2536I1.1
CTD-2536I1.1
chr22_-_32767017 1.61 ENST00000400234.1
RFPL3S
RFPL3 antisense
chrX_-_14891150 1.61 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
FANCB
Fanconi anemia, complementation group B
chrX_+_134654540 1.59 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr18_-_5396271 1.59 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr8_-_71157595 1.57 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr6_-_109776901 1.56 ENST00000431946.1
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr6_+_28249299 1.55 ENST00000405948.2
PGBD1
piggyBac transposable element derived 1
chrX_+_1710484 1.54 ENST00000313871.3
ENST00000381261.3
AKAP17A
A kinase (PRKA) anchor protein 17A
chr9_+_44868935 1.53 ENST00000448436.2
RP11-160N1.10
RP11-160N1.10
chr6_-_84419101 1.44 ENST00000520302.1
ENST00000520213.1
ENST00000439399.2
ENST00000428679.2
ENST00000437520.1
SNAP91
synaptosomal-associated protein, 91kDa
chr11_+_115498761 1.43 ENST00000424313.2
AP000997.1
AP000997.1
chr11_-_114430570 1.43 ENST00000251921.2
NXPE1
neurexophilin and PC-esterase domain family, member 1
chr12_+_54422142 1.42 ENST00000243108.4
HOXC6
homeobox C6
chr17_-_37934466 1.41 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr12_+_9980069 1.40 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr5_-_11588907 1.39 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr1_-_167487808 1.38 ENST00000392122.3
CD247
CD247 molecule
chr12_+_56324933 1.36 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr3_+_114012819 1.35 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr12_+_56324756 1.35 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chrX_-_142605301 1.33 ENST00000370503.2
SPANXN3
SPANX family, member N3
chr19_-_7812446 1.32 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr12_-_10541575 1.32 ENST00000540818.1
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr11_+_101785727 1.30 ENST00000263468.8
KIAA1377
KIAA1377
chr6_+_28249332 1.29 ENST00000259883.3
PGBD1
piggyBac transposable element derived 1
chr19_-_39805976 1.28 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr7_-_36634181 1.25 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr1_+_84630645 1.24 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_145278475 1.18 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr17_-_8113542 1.15 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB
aurora kinase B
chr14_+_52327109 1.15 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr1_+_111415757 1.14 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr14_+_52327350 1.14 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr6_-_109777128 1.13 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr14_+_55595762 1.11 ENST00000254301.9
LGALS3
lectin, galactoside-binding, soluble, 3
chr18_-_3874271 1.10 ENST00000400149.3
ENST00000400155.1
ENST00000400150.3
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr14_+_101295638 1.09 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr6_+_130339710 1.08 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr4_+_146601356 1.08 ENST00000438731.1
ENST00000511965.1
C4orf51
chromosome 4 open reading frame 51
chr19_-_7812397 1.07 ENST00000593660.1
ENST00000354397.6
ENST00000593821.1
ENST00000602261.1
ENST00000315591.8
ENST00000394161.5
ENST00000204801.8
ENST00000601256.1
ENST00000601951.1
ENST00000315599.7
CD209
CD209 molecule
chr1_+_84630574 1.06 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_+_36450169 1.02 ENST00000428612.1
ANLN
anillin, actin binding protein
chr11_+_7506584 1.01 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr1_+_74701062 0.99 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr2_-_158345341 0.98 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr7_-_105332084 0.98 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr12_+_9980113 0.97 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr1_+_158985457 0.97 ENST00000567661.1
ENST00000474473.1
IFI16
interferon, gamma-inducible protein 16
chr4_-_164534657 0.94 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr7_-_20256965 0.92 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr14_-_92247032 0.90 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr14_+_22964877 0.84 ENST00000390494.1
TRAJ43
T cell receptor alpha joining 43
chr11_+_62037622 0.84 ENST00000227918.2
ENST00000525380.1
SCGB2A2
secretoglobin, family 2A, member 2
chr3_-_123512688 0.82 ENST00000475616.1
MYLK
myosin light chain kinase
chr4_-_120243545 0.81 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr1_+_44514040 0.80 ENST00000431800.1
ENST00000437643.1
RP5-1198O20.4
RP5-1198O20.4
chr5_+_82767487 0.79 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr11_-_66964638 0.78 ENST00000444002.2
AP001885.1
AP001885.1
chr5_+_55354822 0.78 ENST00000511861.1
CTD-2227I18.1
CTD-2227I18.1
chrX_+_69501943 0.78 ENST00000509895.1
ENST00000374473.2
ENST00000276066.4
RAB41
RAB41, member RAS oncogene family
chr10_+_17270214 0.78 ENST00000544301.1
VIM
vimentin
chr14_+_31046959 0.76 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr14_+_55595960 0.69 ENST00000554715.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr1_-_149908217 0.68 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr2_+_202098203 0.68 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr19_-_53758094 0.67 ENST00000601828.1
ENST00000598513.1
ENST00000599012.1
ENST00000333952.4
ENST00000598806.1
ZNF677
zinc finger protein 677
chr2_+_196313239 0.66 ENST00000413290.1
AC064834.1
AC064834.1
chr5_-_177207634 0.65 ENST00000513554.1
ENST00000440605.3
FAM153A
family with sequence similarity 153, member A
chr6_+_26240561 0.64 ENST00000377745.2
HIST1H4F
histone cluster 1, H4f
chr9_+_90112117 0.64 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr19_-_53757941 0.64 ENST00000594517.1
ENST00000601413.1
ENST00000594681.1
ZNF677
zinc finger protein 677
chr1_+_158815588 0.64 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr17_-_48785216 0.63 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr17_-_42441204 0.62 ENST00000293443.7
FAM171A2
family with sequence similarity 171, member A2
chr22_+_51176624 0.62 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr11_+_92085262 0.61 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr1_-_72566613 0.61 ENST00000306821.3
NEGR1
neuronal growth regulator 1
chr8_-_25281747 0.60 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr2_-_109605663 0.60 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr10_+_135050908 0.59 ENST00000325980.9
VENTX
VENT homeobox
chr15_+_51669513 0.59 ENST00000558426.1
GLDN
gliomedin
chr7_-_142104553 0.58 ENST00000390379.1
TRBV6-9
T cell receptor beta variable 6-9
chr10_+_97709725 0.58 ENST00000472454.2
RP11-248J23.6
Protein LOC100652732
chr5_+_82767583 0.57 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr5_+_82767284 0.55 ENST00000265077.3
VCAN
versican
chr12_+_9066472 0.51 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_-_2461684 0.51 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr3_-_93781750 0.51 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr9_-_23779367 0.51 ENST00000440102.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr14_-_101295407 0.50 ENST00000596284.1
AL117190.2
AL117190.2
chr1_+_224370873 0.49 ENST00000323699.4
ENST00000391877.3
DEGS1
delta(4)-desaturase, sphingolipid 1
chr12_+_82752647 0.48 ENST00000550058.1
METTL25
methyltransferase like 25
chr6_+_136172820 0.47 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr9_-_15510287 0.46 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr13_-_52733670 0.46 ENST00000550841.1
NEK3
NIMA-related kinase 3
chr9_+_130026756 0.46 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr4_+_5527117 0.46 ENST00000505296.1
C4orf6
chromosome 4 open reading frame 6
chr9_+_75229616 0.45 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr19_-_45457264 0.44 ENST00000591646.1
CTB-129P6.11
Uncharacterized protein
chr7_-_32338917 0.44 ENST00000396193.1
PDE1C
phosphodiesterase 1C, calmodulin-dependent 70kDa
chrX_-_119149501 0.44 ENST00000454625.1
GS1-421I3.2
GS1-421I3.2
chr5_+_175490540 0.43 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr14_+_22987424 0.42 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr16_+_21689835 0.42 ENST00000286149.4
ENST00000388958.3
OTOA
otoancorin
chr1_-_35450897 0.41 ENST00000373337.3
ZMYM6NB
ZMYM6 neighbor
chr12_+_48592134 0.41 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr13_-_52733980 0.41 ENST00000339406.3
NEK3
NIMA-related kinase 3
chr6_-_32557610 0.40 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr7_-_116607526 0.40 ENST00000420664.1
AC106873.4
Uncharacterized protein
chr4_+_5526883 0.40 ENST00000195455.2
C4orf6
chromosome 4 open reading frame 6
chr19_-_53662257 0.38 ENST00000599096.1
ENST00000334197.7
ENST00000597183.1
ENST00000601804.1
ENST00000601469.2
ENST00000452676.2
ZNF347
zinc finger protein 347
chr8_-_99057742 0.38 ENST00000521291.1
ENST00000396070.2
ENST00000523172.1
ENST00000287038.3
RPL30
ribosomal protein L30
chr6_+_134758827 0.38 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr8_+_117963190 0.37 ENST00000427715.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr3_-_180397256 0.37 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr1_-_20503917 0.36 ENST00000429261.2
PLA2G2C
phospholipase A2, group IIC
chr3_+_93781728 0.36 ENST00000314622.4
NSUN3
NOP2/Sun domain family, member 3
chr4_+_9446156 0.35 ENST00000334879.1
DEFB131
defensin, beta 131
chr1_-_114429997 0.35 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr9_+_133539981 0.35 ENST00000253008.2
PRDM12
PR domain containing 12
chr7_-_16840820 0.32 ENST00000450569.1
AGR2
anterior gradient 2
chr2_-_207583120 0.32 ENST00000452335.2
DYTN
dystrotelin
chr14_+_22994472 0.32 ENST00000390519.1
TRAJ18
T cell receptor alpha joining 18
chr6_+_28092338 0.32 ENST00000340487.4
ZSCAN16
zinc finger and SCAN domain containing 16
chr2_-_31361543 0.32 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr21_+_33671264 0.31 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr3_+_108308513 0.31 ENST00000361582.3
DZIP3
DAZ interacting zinc finger protein 3
chr13_-_47471155 0.31 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chrX_-_122756660 0.30 ENST00000441692.1
THOC2
THO complex 2
chr4_+_119809984 0.30 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr21_+_17792672 0.30 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr18_+_29598335 0.29 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr9_+_67977438 0.28 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr2_-_219031709 0.28 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1
chr16_-_71518504 0.28 ENST00000565100.2
ZNF19
zinc finger protein 19
chr11_+_60681346 0.28 ENST00000227525.3
TMEM109
transmembrane protein 109
chr3_+_171561127 0.28 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr2_-_136288113 0.28 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr7_-_55620433 0.27 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr15_-_77712477 0.27 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr12_+_14561422 0.27 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr5_-_147162078 0.25 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chrX_-_103499602 0.24 ENST00000372588.4
ESX1
ESX homeobox 1
chr14_+_22997487 0.24 ENST00000390521.1
TRAJ16
T cell receptor alpha joining 16
chr16_+_53412368 0.23 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr1_-_185597619 0.23 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr6_-_32908765 0.23 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_32095968 0.22 ENST00000375203.3
ENST00000375201.4
ATF6B
activating transcription factor 6 beta
chr11_-_114430588 0.22 ENST00000534921.1
NXPE1
neurexophilin and PC-esterase domain family, member 1
chr20_+_52824367 0.21 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr14_+_22133297 0.21 ENST00000408935.1
OR4E2
olfactory receptor, family 4, subfamily E, member 2
chr14_-_73997901 0.21 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr18_-_3874247 0.19 ENST00000581699.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_242498135 0.16 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr1_-_158656386 0.16 ENST00000467387.1
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr10_-_32667660 0.15 ENST00000375110.2
EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr2_-_77749387 0.14 ENST00000409884.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr11_+_59855724 0.14 ENST00000524868.1
MS4A2
membrane-spanning 4-domains, subfamily A, member 2
chr2_-_77749336 0.13 ENST00000409282.1
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr5_+_140762268 0.13 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr13_-_86373536 0.13 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrY_-_2655644 0.13 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
SRY
sex determining region Y
chr21_+_33671160 0.12 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr14_+_50291993 0.12 ENST00000595378.1
AL627171.2
HCG1786899; PRO2610; Uncharacterized protein
chr12_+_7864021 0.12 ENST00000345088.2
DPPA3
developmental pluripotency associated 3
chr15_+_77712993 0.11 ENST00000336216.4
ENST00000381714.3
ENST00000558651.1
HMG20A
high mobility group 20A
chr15_+_77713222 0.11 ENST00000558176.1
HMG20A
high mobility group 20A
chr11_-_92931098 0.11 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr12_+_105380073 0.11 ENST00000552951.1
ENST00000280749.5
C12orf45
chromosome 12 open reading frame 45
chr2_-_77749474 0.11 ENST00000409093.1
ENST00000409088.3
LRRTM4
leucine rich repeat transmembrane neuronal 4
chr3_+_108308559 0.10 ENST00000486815.1
DZIP3
DAZ interacting zinc finger protein 3
chr20_+_5731083 0.10 ENST00000445603.1
ENST00000442185.1
C20orf196
chromosome 20 open reading frame 196
chr15_+_51669444 0.09 ENST00000396399.2
GLDN
gliomedin
chr1_+_202091980 0.09 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr20_+_5731027 0.09 ENST00000378979.4
ENST00000303142.6
C20orf196
chromosome 20 open reading frame 196
chr14_-_64194745 0.08 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr2_-_218621272 0.08 ENST00000423123.1
DIRC3
disrupted in renal carcinoma 3
chr17_-_30228678 0.08 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr1_-_226595741 0.07 ENST00000366794.5
ENST00000366792.1
ENST00000366791.5
PARP1
poly (ADP-ribose) polymerase 1
chr14_+_55494323 0.07 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr2_-_88927092 0.07 ENST00000303236.3
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.5 4.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.5 2.1 GO:0019417 sulfur oxidation(GO:0019417)
0.5 1.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.5 2.4 GO:0046968 peptide antigen transport(GO:0046968)
0.4 1.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.4 1.8 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.3 1.7 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 1.0 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.3 3.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 2.3 GO:0097338 response to clozapine(GO:0097338)
0.2 1.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.5 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.2 0.6 GO:1990637 response to prolactin(GO:1990637)
0.1 0.7 GO:0052148 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 1.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.6 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 1.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 4.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 2.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.3 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 1.8 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 0.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 2.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.5 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.9 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.8 GO:0070307 Bergmann glial cell differentiation(GO:0060020) lens fiber cell development(GO:0070307)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 2.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.6 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 1.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 1.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:1904760 peptidyl-serine ADP-ribosylation(GO:0018312) myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 2.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500) positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.6 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 2.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.9 GO:0036128 CatSper complex(GO:0036128)
0.1 2.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 2.9 GO:0001772 immunological synapse(GO:0001772)
0.0 4.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0070852 cell body fiber(GO:0070852)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 4.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0030055 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 0.2 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0015934 organellar ribosome(GO:0000313) organellar large ribosomal subunit(GO:0000315) mitochondrial ribosome(GO:0005761) mitochondrial large ribosomal subunit(GO:0005762) large ribosomal subunit(GO:0015934) ribosomal subunit(GO:0044391)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.6 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.4 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 1.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.3 1.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 2.4 GO:0046790 virion binding(GO:0046790)
0.2 1.9 GO:0019863 IgE binding(GO:0019863)
0.2 2.4 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 0.6 GO:0004040 amidase activity(GO:0004040)
0.1 0.4 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 2.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 2.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 2.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 2.1 GO:0071949 FAD binding(GO:0071949)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 2.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 3.0 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 1.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.6 GO:0002039 p53 binding(GO:0002039)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.8 PID AURORA B PATHWAY Aurora B signaling
0.1 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 2.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 3.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 2.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1