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Illumina Body Map 2: averaged replicates

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Results for MYOD1

Z-value: 5.35

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Transcription factors associated with MYOD1

Gene Symbol Gene ID Gene Info
MYOD1
ENSG00000129152.3 myogenic differentiation 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v2_chr11_+_17741111_177411240.804.4e-08Click!

Activity profile of MYOD1 motif

Sorted Z-values of MYOD1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_152590946 28.32 ENST00000172853.10
NEB
nebulin
chr3_+_42727011 25.64 ENST00000287777.4
KLHL40
kelch-like family member 40
chr20_+_30407151 23.22 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr20_+_30407105 23.22 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr17_+_33474826 22.31 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B
unc-45 homolog B (C. elegans)
chr17_+_33474860 20.80 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr8_-_41522779 20.31 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic
chr8_-_41522719 20.30 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr16_+_30387141 19.98 ENST00000566955.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr19_-_45826125 19.59 ENST00000221476.3
CKM
creatine kinase, muscle
chr16_+_30383613 19.44 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_175629135 18.67 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_-_175629164 18.66 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr4_-_177190364 18.46 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr11_+_1860200 17.96 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr1_-_24438664 16.17 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3
myomesin 3
chr16_+_30386098 16.14 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr2_-_152590982 16.10 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr3_-_39234074 15.53 ENST00000340369.3
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin-binding repeat containing 1
chr6_+_41021027 14.54 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr22_-_36018569 14.28 ENST00000419229.1
ENST00000406324.1
MB
myoglobin
chr1_-_201391149 14.07 ENST00000555948.1
ENST00000556362.1
TNNI1
troponin I type 1 (skeletal, slow)
chr2_+_170366203 13.91 ENST00000284669.1
KLHL41
kelch-like family member 41
chr11_+_1860832 13.54 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr17_+_65040678 13.42 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr22_-_36013368 12.70 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr11_+_1860682 12.45 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr19_+_50936142 12.44 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr2_+_233390890 12.34 ENST00000258385.3
ENST00000536614.1
ENST00000457943.2
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr3_-_69171739 12.22 ENST00000489031.1
LMOD3
leiomodin 3 (fetal)
chr2_+_233404429 12.13 ENST00000389494.3
ENST00000389492.3
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
chr1_-_201081579 12.03 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr12_-_70093190 11.89 ENST00000330891.5
BEST3
bestrophin 3
chr12_-_70093111 11.80 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr6_-_33714752 11.58 ENST00000451316.1
IP6K3
inositol hexakisphosphate kinase 3
chr12_-_70093065 11.41 ENST00000553096.1
BEST3
bestrophin 3
chr2_+_88367299 11.13 ENST00000419482.2
ENST00000444564.2
SMYD1
SET and MYND domain containing 1
chr17_-_79792909 11.09 ENST00000330261.4
ENST00000570394.1
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr19_+_3933579 10.97 ENST00000593949.1
NMRK2
nicotinamide riboside kinase 2
chr3_-_52486841 10.56 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr19_-_2256405 10.12 ENST00000300961.6
JSRP1
junctional sarcoplasmic reticulum protein 1
chr5_+_150040403 10.06 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr15_-_42749711 9.78 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr8_-_144512576 9.75 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr14_+_24600484 9.74 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr2_+_88367368 9.63 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr6_+_17281573 9.55 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr14_-_65346555 9.49 ENST00000542895.1
ENST00000556626.1
SPTB
spectrin, beta, erythrocytic
chr2_-_179672142 9.48 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr9_-_35685452 9.36 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr3_+_35721106 9.31 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_70093162 9.07 ENST00000551160.1
BEST3
bestrophin 3
chr3_-_155011483 9.07 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr2_+_233390863 9.07 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr11_-_47470703 9.06 ENST00000298854.2
RAPSN
receptor-associated protein of the synapse
chr2_-_219696519 8.87 ENST00000545803.1
ENST00000430489.1
ENST00000392098.3
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr16_+_7382745 8.85 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_1942580 8.70 ENST00000381558.1
TNNT3
troponin T type 3 (skeletal, fast)
chr20_-_44455976 8.56 ENST00000372555.3
TNNC2
troponin C type 2 (fast)
chr7_-_44105158 8.50 ENST00000297283.3
PGAM2
phosphoglycerate mutase 2 (muscle)
chr2_-_219696511 8.49 ENST00000439262.2
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr19_+_35521572 8.38 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr11_-_119252359 8.35 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr6_+_150464155 8.16 ENST00000361131.4
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr17_-_62066769 8.13 ENST00000577329.1
CTC-264K15.6
CTC-264K15.6
chr19_+_3933085 7.94 ENST00000168977.2
ENST00000599576.1
NMRK2
nicotinamide riboside kinase 2
chr3_+_35721182 7.85 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr9_-_35689900 7.85 ENST00000378300.5
ENST00000329305.2
ENST00000360958.2
TPM2
tropomyosin 2 (beta)
chr11_-_47470682 7.73 ENST00000529341.1
ENST00000352508.3
RAPSN
receptor-associated protein of the synapse
chr12_-_57644952 7.70 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr1_-_144866711 7.67 ENST00000530130.1
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_-_179659669 7.66 ENST00000436599.1
TTN
titin
chr1_-_16345245 7.63 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr11_-_47470591 7.54 ENST00000524487.1
RAPSN
receptor-associated protein of the synapse
chr11_-_17410629 7.46 ENST00000526912.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr17_-_27949911 7.42 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr1_+_78354243 7.20 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr17_-_41132088 7.17 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr17_-_39258461 6.98 ENST00000440582.1
KRTAP4-16P
keratin associated protein 4-16, pseudogene
chr8_-_33455268 6.96 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr19_-_49658387 6.92 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr2_+_220283091 6.91 ENST00000373960.3
DES
desmin
chr14_-_65289812 6.89 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB
spectrin, beta, erythrocytic
chr11_-_119252425 6.86 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr1_+_78354330 6.82 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chr11_+_1940786 6.77 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr10_-_75410771 6.71 ENST00000372873.4
SYNPO2L
synaptopodin 2-like
chr1_-_115238207 6.70 ENST00000520113.2
ENST00000369538.3
ENST00000353928.6
AMPD1
adenosine monophosphate deaminase 1
chr15_-_35088340 6.69 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chrX_-_33357558 6.67 ENST00000288447.4
DMD
dystrophin
chr18_+_7231123 6.67 ENST00000383467.2
LRRC30
leucine rich repeat containing 30
chr3_-_46904946 6.66 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr19_-_49658641 6.65 ENST00000252825.4
HRC
histidine rich calcium binding protein
chr3_-_46904918 6.63 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr14_-_70655684 6.59 ENST00000356921.2
ENST00000381269.2
ENST00000357887.3
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr2_-_227050079 6.57 ENST00000423838.1
AC068138.1
AC068138.1
chr12_-_49393092 6.54 ENST00000421952.2
DDN
dendrin
chr17_+_46132037 6.54 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr8_-_124553437 6.40 ENST00000517956.1
ENST00000443022.2
FBXO32
F-box protein 32
chr3_-_69171708 6.25 ENST00000420581.2
LMOD3
leiomodin 3 (fetal)
chr21_+_30503282 6.08 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr1_+_78354175 6.05 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr6_+_133562472 6.04 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4
eyes absent homolog 4 (Drosophila)
chr1_+_78354297 5.96 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr19_-_49222956 5.93 ENST00000599703.1
ENST00000318083.6
ENST00000419611.1
ENST00000377367.3
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr17_+_46131912 5.84 ENST00000584634.1
ENST00000580050.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr1_+_172422026 5.83 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr1_+_228395755 5.82 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr15_-_40633101 5.81 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr3_+_35681081 5.78 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chrX_+_130192318 5.75 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr10_+_6779326 5.66 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr14_-_94443105 5.66 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr12_-_47226152 5.65 ENST00000546940.1
SLC38A4
solute carrier family 38, member 4
chr12_-_70093235 5.64 ENST00000266661.4
BEST3
bestrophin 3
chr19_+_35521699 5.61 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr3_+_42190714 5.59 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr17_+_46131843 5.58 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr19_+_35521616 5.56 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr12_+_50497784 5.49 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chrX_-_107018969 5.49 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr2_+_173955327 5.33 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr11_+_10476851 5.24 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr10_+_123951957 5.07 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_+_35721130 4.93 ENST00000432450.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr10_+_105253661 4.90 ENST00000369780.4
NEURL
neuralized E3 ubiquitin protein ligase 1
chr4_-_186456652 4.84 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr17_-_80797886 4.82 ENST00000572562.1
ZNF750
zinc finger protein 750
chr10_+_123923105 4.81 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr10_-_62149433 4.80 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_16771936 4.79 ENST00000187762.2
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr21_+_30502806 4.78 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr9_+_34992846 4.66 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_+_6533380 4.64 ENST00000552089.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_150467221 4.63 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr1_+_100316041 4.59 ENST00000370165.3
ENST00000370163.3
ENST00000294724.4
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr20_+_57875658 4.52 ENST00000371025.3
EDN3
endothelin 3
chr7_+_66800928 4.48 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr17_+_45286387 4.47 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr10_+_123923205 4.42 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr19_-_56056888 4.41 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr17_+_45286706 4.33 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr20_+_57875758 4.30 ENST00000395654.3
EDN3
endothelin 3
chr6_-_127780510 4.26 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr10_+_123922941 4.25 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr3_-_52868931 4.23 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr7_+_140774032 4.22 ENST00000565468.1
TMEM178B
transmembrane protein 178B
chr6_-_45983581 4.18 ENST00000339561.6
CLIC5
chloride intracellular channel 5
chr6_-_125766306 4.11 ENST00000430672.1
RP11-138M12.1
RP11-138M12.1
chr7_+_107301447 4.06 ENST00000440056.1
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr8_-_145018080 3.90 ENST00000354589.3
PLEC
plectin
chr3_+_187420101 3.90 ENST00000449623.1
ENST00000437407.1
RP11-211G3.3
Uncharacterized protein
chr16_+_83932684 3.89 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr4_-_186456766 3.86 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr1_+_46379254 3.79 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr3_+_159570722 3.78 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr6_-_160147925 3.78 ENST00000535561.1
SOD2
superoxide dismutase 2, mitochondrial
chr1_+_16062820 3.76 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr3_+_32148106 3.72 ENST00000425459.1
ENST00000431009.1
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr2_-_220118631 3.72 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr1_+_6615241 3.71 ENST00000333172.6
ENST00000328191.4
ENST00000351136.3
TAS1R1
taste receptor, type 1, member 1
chr2_-_220435963 3.67 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1
obscurin-like 1
chr6_+_133561725 3.60 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr1_+_201857798 3.60 ENST00000362011.6
SHISA4
shisa family member 4
chr11_-_111783595 3.59 ENST00000528628.1
CRYAB
crystallin, alpha B
chr13_+_76334795 3.59 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr10_-_75193308 3.56 ENST00000299432.2
MSS51
MSS51 mitochondrial translational activator
chr18_+_18943554 3.54 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr5_-_59783882 3.50 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_30848829 3.49 ENST00000508317.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr13_+_76334567 3.46 ENST00000321797.8
LMO7
LIM domain 7
chr3_-_52869205 3.40 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr1_-_57285038 3.39 ENST00000343433.6
C1orf168
chromosome 1 open reading frame 168
chr19_+_35532612 3.37 ENST00000600390.1
ENST00000597419.1
HPN
hepsin
chr13_+_76334498 3.35 ENST00000534657.1
LMO7
LIM domain 7
chr1_+_100315613 3.30 ENST00000361915.3
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr6_+_30848771 3.29 ENST00000503180.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_+_76165213 3.24 ENST00000590201.1
SYNGR2
synaptogyrin 2
chr5_-_150466692 3.23 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr11_-_123525648 3.21 ENST00000527836.1
SCN3B
sodium channel, voltage-gated, type III, beta subunit
chr2_-_220436248 3.18 ENST00000265318.4
OBSL1
obscurin-like 1
chr5_-_58335281 3.18 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_-_26625169 3.16 ENST00000319420.3
SHISA2
shisa family member 2
chr1_-_154164534 3.16 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr1_-_201346761 3.15 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr22_+_45680822 3.15 ENST00000216211.4
ENST00000396082.2
UPK3A
uroplakin 3A
chr6_+_30848740 3.10 ENST00000505534.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_7216939 3.10 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr10_+_120789223 3.04 ENST00000425699.1
NANOS1
nanos homolog 1 (Drosophila)
chr19_-_56048456 3.00 ENST00000413299.1
SBK2
SH3 domain binding kinase family, member 2
chr1_+_22328144 3.00 ENST00000290122.3
ENST00000374663.1
CELA3A
chymotrypsin-like elastase family, member 3A
chrX_+_119495934 2.99 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATP1B4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr17_+_76164639 2.98 ENST00000225777.3
ENST00000585591.1
ENST00000589711.1
ENST00000588282.1
ENST00000589168.1
SYNGR2
synaptogyrin 2
chr1_-_154842741 2.96 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr17_-_3301704 2.96 ENST00000322608.2
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr6_+_30848557 2.92 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr19_-_56047661 2.91 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr2_+_228029281 2.90 ENST00000396578.3
COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr3_+_32147997 2.88 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr6_-_45983549 2.84 ENST00000544153.1
CLIC5
chloride intracellular channel 5

Network of associatons between targets according to the STRING database.

First level regulatory network of MYOD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 44.4 GO:0007525 somatic muscle development(GO:0007525)
8.6 60.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
8.1 24.3 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
6.5 58.7 GO:0048630 skeletal muscle tissue growth(GO:0048630)
4.9 19.5 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
4.5 13.6 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
4.0 12.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
3.7 25.6 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
3.4 27.0 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
3.3 42.8 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.4 35.5 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
2.1 8.5 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
1.8 134.9 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.7 7.0 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
1.7 6.8 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
1.6 40.8 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
1.6 7.9 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.5 26.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.5 14.5 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
1.3 8.8 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
1.2 4.8 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
1.2 20.2 GO:0006600 creatine metabolic process(GO:0006600)
1.2 3.6 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
1.1 11.9 GO:0032264 IMP salvage(GO:0032264)
1.1 9.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.0 6.1 GO:0018032 protein amidation(GO:0018032)
1.0 19.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
1.0 12.0 GO:0071313 cellular response to caffeine(GO:0071313)
1.0 3.8 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.9 8.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.9 2.7 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.8 2.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.8 5.1 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.8 5.8 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.8 4.8 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.8 14.0 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.8 3.9 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.8 15.2 GO:0045475 locomotor rhythm(GO:0045475)
0.8 3.8 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7 6.6 GO:1990034 calcium ion export from cell(GO:1990034)
0.7 4.3 GO:0036309 protein localization to M-band(GO:0036309)
0.7 6.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.6 2.6 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.6 5.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.6 3.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.6 11.5 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 1.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.6 1.7 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.6 7.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.6 25.9 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.5 3.7 GO:0050917 sensory perception of umami taste(GO:0050917)
0.5 3.7 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.5 18.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.5 7.8 GO:0071316 cellular response to nicotine(GO:0071316)
0.5 17.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.5 1.9 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.5 1.9 GO:1903028 positive regulation of opsonization(GO:1903028)
0.5 3.8 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.5 6.5 GO:0015705 iodide transport(GO:0015705)
0.4 18.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.4 1.6 GO:1904647 response to rotenone(GO:1904647)
0.4 7.0 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.4 7.4 GO:0014870 response to muscle inactivity(GO:0014870)
0.4 1.6 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.4 7.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.4 1.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.4 9.5 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.4 5.6 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.4 1.1 GO:1903361 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) protein localization to basolateral plasma membrane(GO:1903361) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.4 1.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 2.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.4 2.8 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.4 2.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.4 3.2 GO:0015840 urea transport(GO:0015840)
0.3 2.1 GO:0019087 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.3 1.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.3 4.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.3 14.4 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.3 1.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 43.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 1.8 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.3 1.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 12.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 1.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.3 1.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.3 1.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.3 8.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 25.4 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.3 2.0 GO:0023021 termination of signal transduction(GO:0023021)
0.2 1.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.2 3.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 2.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 0.9 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 2.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 2.8 GO:0051450 myoblast proliferation(GO:0051450)
0.2 46.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 34.6 GO:0043271 negative regulation of ion transport(GO:0043271)
0.2 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 3.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.2 1.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.2 4.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.8 GO:0008050 female courtship behavior(GO:0008050)
0.2 10.4 GO:0030239 myofibril assembly(GO:0030239)
0.2 15.8 GO:0051693 actin filament capping(GO:0051693)
0.2 3.5 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 0.8 GO:0035262 gonad morphogenesis(GO:0035262)
0.2 3.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2 0.9 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.2 1.5 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 2.8 GO:0000050 urea cycle(GO:0000050)
0.2 1.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 1.7 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.2 1.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.0 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.2 1.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 1.0 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 1.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 30.4 GO:0034605 cellular response to heat(GO:0034605)
0.1 2.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 7.3 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 2.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 10.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 1.0 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.7 GO:0030091 protein repair(GO:0030091)
0.1 2.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.0 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.1 0.5 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.6 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 2.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.7 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 3.8 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.8 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 5.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.6 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 2.3 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 1.1 GO:0006013 mannose metabolic process(GO:0006013)
0.1 2.5 GO:0044070 regulation of anion transport(GO:0044070)
0.1 3.3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.1 0.5 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.4 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 1.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 2.2 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.1 0.9 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 2.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.6 GO:0048747 muscle fiber development(GO:0048747)
0.1 2.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 0.5 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 2.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 0.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 2.2 GO:0035729 cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.1 2.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 11.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.6 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 2.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.3 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 1.3 GO:0015747 urate transport(GO:0015747)
0.1 13.7 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 6.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 5.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.6 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 0.2 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.9 GO:0042472 inner ear morphogenesis(GO:0042472)
0.1 1.9 GO:0007517 muscle organ development(GO:0007517)
0.1 1.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.8 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.1 3.0 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.0 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.4 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.9 GO:0006413 translational initiation(GO:0006413)
0.1 1.8 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.6 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 1.8 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 6.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 2.7 GO:0006308 DNA catabolic process(GO:0006308)
0.1 0.3 GO:0035803 egg coat formation(GO:0035803)
0.1 0.7 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 5.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 12.0 GO:0006986 response to unfolded protein(GO:0006986)
0.0 2.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 10.9 GO:0031424 keratinization(GO:0031424)
0.0 1.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 1.0 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.4 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0021678 third ventricle development(GO:0021678)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.6 GO:0072189 ureter development(GO:0072189)
0.0 0.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.2 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.7 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.9 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 2.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 1.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581) negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 10.3 GO:0000209 protein polyubiquitination(GO:0000209)
0.0 1.8 GO:0006953 acute-phase response(GO:0006953)
0.0 2.4 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.0 GO:0061009 common bile duct development(GO:0061009)
0.0 0.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.1 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.8 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 5.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.8 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 1.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.8 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.3 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.5 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.3 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.5 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.1 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 2.3 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 3.3 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 95.8 GO:0005861 troponin complex(GO:0005861)
2.6 121.5 GO:0005859 muscle myosin complex(GO:0005859)
2.5 70.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
2.3 6.9 GO:0097512 cardiac myofibril(GO:0097512)
2.1 61.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.7 12.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.4 24.3 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.4 6.9 GO:0042643 actomyosin, actin portion(GO:0042643)
1.0 74.7 GO:0031672 A band(GO:0031672)
0.9 24.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.9 7.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.8 13.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.8 2.5 GO:0018444 translation release factor complex(GO:0018444)
0.8 16.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.8 19.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.7 12.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 1.9 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.6 158.4 GO:0030017 sarcomere(GO:0030017)
0.6 5.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4 20.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 46.1 GO:0034707 chloride channel complex(GO:0034707)
0.4 1.6 GO:1902912 pyruvate kinase complex(GO:1902912)
0.4 37.0 GO:0016528 sarcoplasm(GO:0016528)
0.3 2.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.3 3.8 GO:0030870 Mre11 complex(GO:0030870)
0.3 1.5 GO:0031417 NatC complex(GO:0031417)
0.3 6.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 10.2 GO:0030016 myofibril(GO:0030016)
0.2 10.8 GO:0000421 autophagosome membrane(GO:0000421)
0.2 3.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 4.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 8.8 GO:0031941 filamentous actin(GO:0031941)
0.1 2.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 11.8 GO:0045095 keratin filament(GO:0045095)
0.1 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.7 GO:0031088 platelet dense granule membrane(GO:0031088) multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0035976 AP1 complex(GO:0035976)
0.1 1.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 3.6 GO:0097440 apical dendrite(GO:0097440)
0.1 0.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.7 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 2.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.0 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 7.6 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 7.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 5.2 GO:0035580 specific granule lumen(GO:0035580)
0.1 2.0 GO:0042599 lamellar body(GO:0042599)
0.1 4.6 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.5 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 7.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 1.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 5.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.6 GO:0016459 myosin complex(GO:0016459)
0.1 0.5 GO:0005638 lamin filament(GO:0005638)
0.1 1.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.8 GO:0060091 kinocilium(GO:0060091)
0.1 5.1 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 4.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.9 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0030686 90S preribosome(GO:0030686)
0.0 1.1 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 4.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 19.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0045178 basal part of cell(GO:0045178)
0.0 7.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 6.0 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.5 GO:0090544 BAF-type complex(GO:0090544)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 19.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
4.7 18.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
4.6 46.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
4.4 22.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
4.0 12.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
3.9 54.5 GO:0031014 troponin T binding(GO:0031014)
3.9 15.5 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
2.8 70.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
2.3 11.6 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
2.1 8.5 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
2.0 19.6 GO:0004111 creatine kinase activity(GO:0004111)
1.8 27.2 GO:0031433 telethonin binding(GO:0031433)
1.8 7.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
1.8 8.8 GO:0031708 endothelin B receptor binding(GO:0031708)
1.7 40.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.6 14.5 GO:0004126 cytidine deaminase activity(GO:0004126)
1.6 202.6 GO:0008307 structural constituent of muscle(GO:0008307)
1.6 3.2 GO:0030172 troponin C binding(GO:0030172)
1.3 19.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.2 27.0 GO:0005344 oxygen transporter activity(GO:0005344)
1.2 11.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.0 5.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.0 6.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.0 7.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.9 6.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.9 16.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.9 23.8 GO:0030506 ankyrin binding(GO:0030506)
0.9 17.6 GO:0005523 tropomyosin binding(GO:0005523)
0.9 3.5 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.8 7.4 GO:0043426 MRF binding(GO:0043426)
0.8 6.5 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.8 24.3 GO:0043495 protein anchor(GO:0043495)
0.6 43.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.6 2.4 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.6 7.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.6 1.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.5 2.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 4.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.5 12.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 3.8 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 2.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.4 6.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 1.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.4 2.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.4 7.4 GO:0050811 GABA receptor binding(GO:0050811)
0.3 13.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 1.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.3 2.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 2.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.3 47.2 GO:0005254 chloride channel activity(GO:0005254)
0.3 7.6 GO:0031005 filamin binding(GO:0031005)
0.3 6.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 1.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 2.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 18.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.3 3.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 20.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 1.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.7 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 2.9 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.2 1.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 13.5 GO:0030332 cyclin binding(GO:0030332)
0.2 0.7 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.2 0.4 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.2 2.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 2.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 2.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 0.8 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 0.6 GO:0070984 SET domain binding(GO:0070984)
0.2 3.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 5.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 1.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.2 5.8 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 2.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 2.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 4.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.2 2.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 2.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 4.9 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 4.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.6 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 6.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 3.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 1.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.9 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 3.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 6.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.8 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.2 GO:0016406 carnitine O-acyltransferase activity(GO:0016406) O-acetyltransferase activity(GO:0016413)
0.1 8.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.8 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 2.3 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 65.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.7 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 10.4 GO:0051117 ATPase binding(GO:0051117)
0.1 0.8 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 14.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 6.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 5.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.9 GO:0043531 ADP binding(GO:0043531)
0.1 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 21.1 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.2 GO:0070628 proteasome binding(GO:0070628)
0.1 3.0 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.6 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 1.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.5 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 3.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 2.1 GO:0005123 death receptor binding(GO:0005123)
0.1 15.6 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 9.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 3.8 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 1.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 7.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.7 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 2.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 3.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 1.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 3.0 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 2.7 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 1.4 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 1.7 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 1.3 GO:0042393 histone binding(GO:0042393)
0.0 11.9 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 1.6 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 5.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 1.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0070740 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 46.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 7.5 PID ENDOTHELIN PATHWAY Endothelins
0.3 32.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.3 5.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2 49.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 9.8 PID FOXO PATHWAY FoxO family signaling
0.1 14.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 8.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 3.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 7.3 PID AURORA B PATHWAY Aurora B signaling
0.1 9.1 PID NOTCH PATHWAY Notch signaling pathway
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 3.8 PID ATM PATHWAY ATM pathway
0.1 5.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 2.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 2.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 70.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
2.5 190.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.7 86.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.6 16.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 11.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.4 15.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 9.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 12.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 9.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 13.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 11.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 8.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 32.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 4.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 5.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 29.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 2.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 2.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 2.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 6.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 4.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation