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Illumina Body Map 2: averaged replicates

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Results for NANOG

Z-value: 1.11

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Transcription factors associated with NANOG

Gene Symbol Gene ID Gene Info
NANOG
ENSG00000111704.6 Nanog homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NANOGhg19_v2_chr12_+_7941989_79420140.183.1e-01Click!

Activity profile of NANOG motif

Sorted Z-values of NANOG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_78526855 2.65 ENST00000541759.1
ENST00000558130.1
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr22_+_26565440 2.62 ENST00000404234.3
ENST00000529632.2
ENST00000360929.3
ENST00000248933.6
ENST00000343706.4
SEZ6L
seizure related 6 homolog (mouse)-like
chr10_-_134599556 2.51 ENST00000368592.5
NKX6-2
NK6 homeobox 2
chr5_+_156693159 1.99 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_+_156693091 1.88 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_56809534 1.88 ENST00000497267.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_+_64133934 1.87 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
ZNF365
zinc finger protein 365
chr2_+_171673072 1.87 ENST00000358196.3
ENST00000375272.1
GAD1
glutamate decarboxylase 1 (brain, 67kDa)
chr6_+_52226897 1.80 ENST00000442253.2
PAQR8
progestin and adipoQ receptor family member VIII
chr22_-_30662828 1.77 ENST00000403463.1
ENST00000215781.2
OSM
oncostatin M
chr20_-_21494654 1.74 ENST00000377142.4
NKX2-2
NK2 homeobox 2
chr10_+_129845670 1.65 ENST00000467366.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_+_129845823 1.61 ENST00000306042.5
PTPRE
protein tyrosine phosphatase, receptor type, E
chr4_+_79567057 1.54 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr10_-_73497581 1.47 ENST00000398786.2
C10orf105
chromosome 10 open reading frame 105
chr17_-_34417479 1.45 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chrX_+_103357202 1.35 ENST00000537356.3
ZCCHC18
zinc finger, CCHC domain containing 18
chr6_+_155537771 1.34 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr19_-_54327542 1.24 ENST00000391775.3
ENST00000324134.6
ENST00000535162.1
ENST00000351894.4
ENST00000354278.3
ENST00000391773.1
ENST00000345770.5
ENST00000391772.1
NLRP12
NLR family, pyrin domain containing 12
chr11_-_67205538 1.19 ENST00000326294.3
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr1_-_28520384 1.15 ENST00000305392.3
PTAFR
platelet-activating factor receptor
chr17_-_72542278 1.13 ENST00000330793.1
CD300C
CD300c molecule
chr10_-_118885954 1.11 ENST00000392901.4
KIAA1598
KIAA1598
chrX_+_85403487 1.11 ENST00000373125.4
DACH2
dachshund homolog 2 (Drosophila)
chr14_-_57272366 1.08 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chrX_+_85403445 1.05 ENST00000373131.1
DACH2
dachshund homolog 2 (Drosophila)
chrX_-_118827333 1.04 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chrX_-_118827113 1.04 ENST00000394617.2
SEPT6
septin 6
chr1_-_47655686 1.01 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr7_-_78400364 1.01 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr20_-_3762087 0.99 ENST00000379756.3
SPEF1
sperm flagellar 1
chr1_-_202129704 0.98 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr8_-_91095099 0.98 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_-_155959853 0.96 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_-_98241598 0.94 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1
claudin domain containing 1
chrX_+_17653413 0.93 ENST00000398097.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_116383738 0.92 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr11_+_63870660 0.92 ENST00000246841.3
FLRT1
fibronectin leucine rich transmembrane protein 1
chr12_-_57410304 0.90 ENST00000441881.1
ENST00000458521.2
TAC3
tachykinin 3
chr14_+_22981834 0.88 ENST00000390507.1
TRAJ30
T cell receptor alpha joining 30
chr2_-_214016314 0.88 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr13_+_108921977 0.88 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr1_+_159272111 0.87 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr3_-_98241358 0.87 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr4_+_154073469 0.86 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr22_+_42095497 0.86 ENST00000401548.3
ENST00000540833.1
ENST00000400107.1
ENST00000300398.4
MEI1
meiosis inhibitor 1
chr3_+_75955817 0.83 ENST00000487694.3
ENST00000602589.1
ROBO2
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr17_-_61045902 0.82 ENST00000581596.1
RP11-180P8.3
RP11-180P8.3
chr19_-_42806919 0.82 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr4_-_5891918 0.81 ENST00000512574.1
CRMP1
collapsin response mediator protein 1
chr13_+_108922228 0.80 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr12_-_85306594 0.80 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr14_-_98444438 0.79 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr1_-_202129105 0.79 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr4_+_79567314 0.78 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr2_+_149402009 0.78 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr16_+_640055 0.78 ENST00000568586.1
ENST00000538492.1
ENST00000248139.3
RAB40C
RAB40C, member RAS oncogene family
chr17_-_61777459 0.78 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chrX_+_14547632 0.77 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr16_+_68573116 0.77 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
ZFP90
ZFP90 zinc finger protein
chr12_-_85306562 0.77 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr22_-_30814469 0.75 ENST00000598426.1
KIAA1658
KIAA1658
chr14_+_67999999 0.75 ENST00000329153.5
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr2_-_112237835 0.73 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chrX_-_19765692 0.73 ENST00000432234.1
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_21392553 0.72 ENST00000279451.4
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr19_+_42381173 0.72 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr12_-_123201337 0.72 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr10_-_48390973 0.71 ENST00000224600.4
RBP3
retinol binding protein 3, interstitial
chr6_+_32407619 0.69 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr1_+_198985262 0.69 ENST00000432488.1
RP11-16L9.4
RP11-16L9.4
chr12_-_42878101 0.68 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr5_-_115872124 0.67 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr3_+_121774202 0.66 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86
CD86 molecule
chr14_-_98444461 0.66 ENST00000499006.2
C14orf64
chromosome 14 open reading frame 64
chr6_+_31540056 0.65 ENST00000418386.2
LTA
lymphotoxin alpha
chr14_+_77647966 0.65 ENST00000554766.1
TMEM63C
transmembrane protein 63C
chr6_+_30525051 0.64 ENST00000376557.3
PRR3
proline rich 3
chr1_+_203097407 0.64 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr1_-_248790491 0.64 ENST00000330803.2
OR2T11
olfactory receptor, family 2, subfamily T, member 11 (gene/pseudogene)
chr4_-_108204904 0.62 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr7_-_142139783 0.61 ENST00000390374.3
TRBV7-6
T cell receptor beta variable 7-6
chr2_-_97536490 0.60 ENST00000449330.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr15_+_77713299 0.59 ENST00000559099.1
HMG20A
high mobility group 20A
chr4_+_79567362 0.59 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr17_-_56606664 0.59 ENST00000580844.1
SEPT4
septin 4
chr6_+_30524663 0.59 ENST00000376560.3
PRR3
proline rich 3
chr2_+_45878407 0.59 ENST00000421201.1
PRKCE
protein kinase C, epsilon
chr19_-_42806444 0.59 ENST00000594989.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr14_+_101295948 0.58 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr14_-_98444369 0.58 ENST00000554822.1
C14orf64
chromosome 14 open reading frame 64
chr22_+_37447771 0.58 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr4_+_154074217 0.58 ENST00000437508.2
TRIM2
tripartite motif containing 2
chr22_+_41487711 0.58 ENST00000263253.7
EP300
E1A binding protein p300
chr7_-_2883928 0.57 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr4_+_114038137 0.55 ENST00000508613.1
ANK2
ankyrin 2, neuronal
chr21_-_35340759 0.55 ENST00000607953.1
AP000569.9
AP000569.9
chr12_-_25055177 0.55 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr19_-_36870087 0.54 ENST00000270001.7
ZFP14
ZFP14 zinc finger protein
chr10_-_49812997 0.53 ENST00000417912.2
ARHGAP22
Rho GTPase activating protein 22
chrX_-_80065146 0.53 ENST00000373275.4
BRWD3
bromodomain and WD repeat domain containing 3
chr19_-_42806842 0.53 ENST00000596265.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr1_+_44870866 0.52 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr2_+_45878790 0.52 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr6_-_30685214 0.52 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr4_+_79567233 0.51 ENST00000514130.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr12_+_25055243 0.51 ENST00000599478.1
AC026310.1
Protein 101060047
chrX_-_133931164 0.51 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr12_-_46663734 0.51 ENST00000550173.1
SLC38A1
solute carrier family 38, member 1
chr14_-_51297837 0.50 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr14_-_98444386 0.50 ENST00000556462.1
ENST00000556138.1
C14orf64
chromosome 14 open reading frame 64
chr17_+_75372165 0.49 ENST00000427674.2
SEPT9
septin 9
chr14_+_22972735 0.48 ENST00000390500.1
TRAJ37
T cell receptor alpha joining 37
chr19_-_42806723 0.48 ENST00000262890.3
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr16_+_68573640 0.48 ENST00000398253.2
ENST00000573161.1
ZFP90
ZFP90 zinc finger protein
chr6_+_163837347 0.47 ENST00000544436.1
QKI
QKI, KH domain containing, RNA binding
chr8_-_101730061 0.47 ENST00000519100.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr20_+_37554955 0.46 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr7_-_76829125 0.46 ENST00000248598.5
FGL2
fibrinogen-like 2
chr14_+_101295638 0.46 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr10_-_49813090 0.46 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr3_-_45837959 0.46 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr16_+_640201 0.46 ENST00000563109.1
RAB40C
RAB40C, member RAS oncogene family
chr1_-_205649580 0.45 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr12_-_51477333 0.43 ENST00000228515.1
ENST00000548206.1
ENST00000546935.1
ENST00000548981.1
CSRNP2
cysteine-serine-rich nuclear protein 2
chr7_-_78400598 0.42 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_+_41549105 0.41 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr17_+_7905912 0.41 ENST00000254854.4
GUCY2D
guanylate cyclase 2D, membrane (retina-specific)
chr6_-_30524951 0.38 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr17_+_7387677 0.38 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_-_92952433 0.38 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr19_+_926000 0.37 ENST00000263620.3
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr15_+_44580899 0.36 ENST00000559222.1
ENST00000299957.6
CASC4
cancer susceptibility candidate 4
chr6_-_136610911 0.36 ENST00000530767.1
ENST00000527759.1
ENST00000527536.1
ENST00000529826.1
ENST00000531224.1
ENST00000353331.4
BCLAF1
BCL2-associated transcription factor 1
chr16_+_14280742 0.35 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr6_-_119031228 0.35 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr7_+_102715315 0.35 ENST00000428183.2
ENST00000323716.3
ENST00000441711.2
ENST00000454559.1
ENST00000425331.1
ENST00000541300.1
ARMC10
armadillo repeat containing 10
chr19_-_13213954 0.34 ENST00000590974.1
LYL1
lymphoblastic leukemia derived sequence 1
chr15_+_44580955 0.34 ENST00000345795.2
ENST00000360824.3
CASC4
cancer susceptibility candidate 4
chr3_-_71803917 0.33 ENST00000421769.2
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr7_-_2883650 0.32 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr14_+_22955216 0.32 ENST00000390486.1
TRAJ52
T cell receptor alpha joining 52
chr3_+_15469058 0.31 ENST00000432764.2
EAF1
ELL associated factor 1
chr7_+_150382781 0.31 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr16_+_3508096 0.31 ENST00000577013.1
ENST00000570819.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr22_+_31090793 0.30 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2
oxysterol binding protein 2
chr8_-_42751728 0.29 ENST00000319104.3
ENST00000531440.1
RNF170
ring finger protein 170
chr22_-_32026810 0.28 ENST00000266095.5
ENST00000397500.1
PISD
phosphatidylserine decarboxylase
chr3_-_15469006 0.28 ENST00000443029.1
ENST00000383790.3
ENST00000383789.5
METTL6
methyltransferase like 6
chr7_-_143956815 0.27 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr3_-_15469045 0.27 ENST00000450816.2
METTL6
methyltransferase like 6
chr19_-_13213662 0.27 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr18_-_23671139 0.27 ENST00000579061.1
ENST00000542420.2
SS18
synovial sarcoma translocation, chromosome 18
chr2_-_175113301 0.27 ENST00000344357.5
ENST00000284719.3
OLA1
Obg-like ATPase 1
chr11_-_72504637 0.27 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr8_-_27469383 0.26 ENST00000519742.1
CLU
clusterin
chr15_+_77713222 0.26 ENST00000558176.1
HMG20A
high mobility group 20A
chr10_-_128110441 0.25 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr4_+_166248775 0.24 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr5_+_72509751 0.24 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr6_-_131277510 0.24 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_107244229 0.23 ENST00000456419.1
ENST00000402163.2
BBX
bobby sox homolog (Drosophila)
chr8_-_42751820 0.23 ENST00000526349.1
ENST00000527424.1
ENST00000534961.1
ENST00000319073.4
RNF170
ring finger protein 170
chr9_+_135285579 0.23 ENST00000343036.2
ENST00000393216.2
C9orf171
chromosome 9 open reading frame 171
chr1_+_151253991 0.23 ENST00000443959.1
ZNF687
zinc finger protein 687
chr3_+_15468862 0.22 ENST00000396842.2
EAF1
ELL associated factor 1
chr7_-_28220354 0.22 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr17_+_43224684 0.22 ENST00000332499.2
HEXIM1
hexamethylene bis-acetamide inducible 1
chr17_-_7387524 0.21 ENST00000311403.4
ZBTB4
zinc finger and BTB domain containing 4
chr3_-_134369853 0.21 ENST00000508956.1
ENST00000503669.1
ENST00000423778.2
KY
kyphoscoliosis peptidase
chr6_+_88032299 0.21 ENST00000608353.1
ENST00000392863.1
ENST00000229570.5
ENST00000608525.1
ENST00000608868.1
SMIM8
small integral membrane protein 8
chr5_+_32585605 0.21 ENST00000265073.4
ENST00000515355.1
ENST00000502897.1
ENST00000510442.1
SUB1
SUB1 homolog (S. cerevisiae)
chrX_+_103173457 0.21 ENST00000419165.1
TMSB15B
thymosin beta 15B
chr3_-_120461353 0.20 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chrX_+_47092314 0.20 ENST00000218348.3
USP11
ubiquitin specific peptidase 11
chr1_+_173837488 0.20 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr4_-_108204846 0.20 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr16_+_3508063 0.20 ENST00000576787.1
ENST00000572942.1
ENST00000576916.1
ENST00000575076.1
ENST00000572131.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr5_-_115872142 0.20 ENST00000510263.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr2_+_87769459 0.19 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr1_-_151254362 0.19 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr3_+_44916098 0.18 ENST00000296125.4
TGM4
transglutaminase 4
chr18_-_23670546 0.17 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr11_-_46142948 0.17 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr1_+_59486059 0.17 ENST00000447329.1
RP4-794H19.4
RP4-794H19.4
chr2_-_175113088 0.17 ENST00000409546.1
ENST00000428402.2
OLA1
Obg-like ATPase 1
chr17_-_43128943 0.16 ENST00000588499.1
ENST00000593094.1
DCAKD
dephospho-CoA kinase domain containing
chr6_+_292253 0.15 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr3_-_120461378 0.15 ENST00000273375.3
RABL3
RAB, member of RAS oncogene family-like 3
chr16_+_30759844 0.14 ENST00000565897.1
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr11_+_26353664 0.14 ENST00000531646.1
ANO3
anoctamin 3
chr11_+_1295809 0.14 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr8_-_27468842 0.14 ENST00000523500.1
CLU
clusterin
chr8_-_102181718 0.13 ENST00000565617.1
KB-1460A1.5
KB-1460A1.5
chr7_-_102715263 0.13 ENST00000379305.3
FBXL13
F-box and leucine-rich repeat protein 13
chr1_+_145576007 0.13 ENST00000369298.1
PIAS3
protein inhibitor of activated STAT, 3
chr1_+_173837214 0.13 ENST00000367704.1
ZBTB37
zinc finger and BTB domain containing 37
chr6_-_107077347 0.13 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr6_-_20212630 0.13 ENST00000324607.7
ENST00000541730.1
ENST00000536798.1
MBOAT1
membrane bound O-acyltransferase domain containing 1
chr12_-_100378392 0.12 ENST00000549866.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of NANOG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.6 1.7 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.5 1.9 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.4 1.2 GO:0043315 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.3 1.7 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.3 0.7 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.3 3.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 0.6 GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.3 0.9 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 1.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.3 0.8 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 1.2 GO:0032661 release of cytoplasmic sequestered NF-kappaB(GO:0008588) regulation of interleukin-18 production(GO:0032661)
0.2 1.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 0.7 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 1.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 0.5 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 1.6 GO:0015820 leucine transport(GO:0015820)
0.1 0.6 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.8 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.1 0.7 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.4 GO:0001172 transcription, RNA-templated(GO:0001172)
0.1 0.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.0 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.0 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 0.6 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.4 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.8 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.6 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.1 2.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.4 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 3.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.0 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.5 GO:0015824 proline transport(GO:0015824)
0.0 0.6 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.9 GO:0045141 meiotic telomere clustering(GO:0045141)
0.0 2.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.9 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.6 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 1.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 1.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.2 GO:0051272 positive regulation of cell migration(GO:0030335) positive regulation of locomotion(GO:0040017) positive regulation of cellular component movement(GO:0051272) positive regulation of cell motility(GO:2000147)
0.0 0.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.9 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.9 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 3.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.2 0.5 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.7 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.9 GO:0060077 inhibitory synapse(GO:0060077) clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.8 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.6 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.4 2.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 1.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.9 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.2 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.2 1.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 1.0 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.8 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 2.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.9 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.9 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0019841 retinol binding(GO:0019841)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0031005 filamin binding(GO:0031005)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 2.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 4.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.1 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.8 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)