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Illumina Body Map 2: averaged replicates

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Results for NFE2L1

Z-value: 1.57

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
NFE2L1
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46126135_461261520.144.4e-01Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_113953705 2.12 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr2_-_158345341 2.00 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr20_+_57594309 1.89 ENST00000217133.1
TUBB1
tubulin, beta 1 class VI
chr12_-_123201337 1.86 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_52887034 1.85 ENST00000330722.6
KRT6A
keratin 6A
chr12_-_123187890 1.84 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr4_-_111563279 1.84 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr11_+_117947782 1.69 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
TMPRSS4
transmembrane protease, serine 4
chr7_-_121944491 1.65 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr4_-_111563076 1.64 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr2_+_217735493 1.60 ENST00000456163.1
AC007557.1
HCG1816075; Uncharacterized protein
chr11_+_60197040 1.59 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr2_-_161056802 1.56 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chrX_+_119029800 1.52 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
AKAP14
A kinase (PRKA) anchor protein 14
chr2_-_161056762 1.51 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr1_-_183538319 1.50 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr11_-_26593649 1.50 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr2_-_152590946 1.49 ENST00000172853.10
NEB
nebulin
chr2_+_149974684 1.47 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr6_-_49834240 1.47 ENST00000335847.4
CRISP1
cysteine-rich secretory protein 1
chr1_+_43613612 1.45 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chrX_+_119030118 1.44 ENST00000371422.1
ENST00000334356.2
AKAP14
A kinase (PRKA) anchor protein 14
chr4_-_177190364 1.44 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr3_+_63638339 1.43 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr6_-_49834209 1.40 ENST00000507853.1
CRISP1
cysteine-rich secretory protein 1
chr11_+_60163775 1.35 ENST00000300187.6
ENST00000395005.2
MS4A14
membrane-spanning 4-domains, subfamily A, member 14
chr15_+_38226827 1.32 ENST00000559502.1
ENST00000558148.1
ENST00000558158.1
TMCO5A
transmembrane and coiled-coil domains 5A
chr11_-_119999539 1.29 ENST00000541857.1
TRIM29
tripartite motif containing 29
chr8_-_30706608 1.29 ENST00000256246.2
TEX15
testis expressed 15
chr11_-_119999611 1.28 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr6_-_22297730 1.27 ENST00000306482.1
PRL
prolactin
chr20_+_59654146 1.26 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr4_+_74606223 1.24 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr11_-_26593677 1.23 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr7_-_142232071 1.21 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr1_+_192127578 1.21 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr6_-_133055815 1.20 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr3_-_52488048 1.18 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr6_-_46048116 1.18 ENST00000185206.6
CLIC5
chloride intracellular channel 5
chr8_-_124665190 1.18 ENST00000325995.7
KLHL38
kelch-like family member 38
chr11_-_26593779 1.17 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr12_+_18891045 1.16 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr14_+_52313833 1.16 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr11_+_60197069 1.16 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr8_+_24298597 1.15 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr3_-_27764190 1.14 ENST00000537516.1
EOMES
eomesodermin
chr8_+_24298531 1.14 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr1_-_95783809 1.12 ENST00000423410.1
RP4-586O15.1
RP4-586O15.1
chr6_+_117586713 1.12 ENST00000352536.3
ENST00000326274.5
VGLL2
vestigial like 2 (Drosophila)
chr14_-_36988882 1.10 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr15_+_22382382 1.09 ENST00000328795.4
OR4N4
olfactory receptor, family 4, subfamily N, member 4
chr1_+_1115056 1.07 ENST00000379288.3
TTLL10
tubulin tyrosine ligase-like family, member 10
chr12_+_10124110 1.06 ENST00000350667.4
CLEC12A
C-type lectin domain family 12, member A
chr19_-_51530916 1.06 ENST00000594768.1
KLK11
kallikrein-related peptidase 11
chr8_+_7716700 1.04 ENST00000454911.2
ENST00000326625.5
SPAG11A
sperm associated antigen 11A
chr6_+_132455526 1.02 ENST00000443303.1
LINC01013
long intergenic non-protein coding RNA 1013
chr19_-_42947121 1.02 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chrX_-_49965663 1.02 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4
A kinase (PRKA) anchor protein 4
chr4_+_71200681 1.01 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr1_+_26517052 1.00 ENST00000338855.2
ENST00000456354.2
CATSPER4
cation channel, sperm associated 4
chr21_+_30672433 1.00 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_+_169926047 1.00 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_115642293 0.99 ENST00000448680.1
RP4-666F24.3
RP4-666F24.3
chr19_-_51538148 0.99 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr1_+_43613566 0.98 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr5_+_131993856 0.97 ENST00000304506.3
IL13
interleukin 13
chr6_+_144185573 0.94 ENST00000237275.6
ENST00000539295.1
ZC2HC1B
zinc finger, C2HC-type containing 1B
chr16_+_19467772 0.94 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5
transmembrane channel-like 5
chr12_-_18890940 0.93 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr6_+_41021027 0.92 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr1_-_154178803 0.91 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr8_-_7309887 0.91 ENST00000458665.1
ENST00000528168.1
SPAG11B
sperm associated antigen 11B
chr4_+_123300121 0.91 ENST00000446706.1
ENST00000296513.2
ADAD1
adenosine deaminase domain containing 1 (testis-specific)
chr10_-_124459284 0.91 ENST00000432000.1
ENST00000329446.4
C10orf120
chromosome 10 open reading frame 120
chr6_-_49755019 0.90 ENST00000304801.3
PGK2
phosphoglycerate kinase 2
chr10_-_23528745 0.90 ENST00000376501.5
C10orf115
chromosome 10 open reading frame 115
chr10_+_127661942 0.89 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr1_-_109399682 0.88 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr1_-_113258090 0.87 ENST00000309276.6
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr22_-_36013368 0.86 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr2_-_158345462 0.86 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr14_+_77292715 0.85 ENST00000393774.3
ENST00000555189.1
ENST00000450042.2
C14orf166B
chromosome 14 open reading frame 166B
chr10_+_35464513 0.84 ENST00000494479.1
ENST00000463314.1
ENST00000342105.3
ENST00000495301.1
ENST00000463960.1
CREM
cAMP responsive element modulator
chr1_+_84873913 0.82 ENST00000370662.3
DNASE2B
deoxyribonuclease II beta
chr15_+_45406519 0.82 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr8_+_24298438 0.82 ENST00000441335.2
ADAM7
ADAM metallopeptidase domain 7
chr20_+_37209820 0.82 ENST00000537425.1
ENST00000373348.3
ENST00000416116.1
ADIG
adipogenin
chr10_-_50122277 0.82 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chrX_-_70326455 0.81 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr14_+_22538811 0.80 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr5_+_127039075 0.79 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr6_+_111408698 0.78 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr14_+_106744269 0.77 ENST00000458560.1
ENST00000415154.1
LINC00226
long intergenic non-protein coding RNA 226
chrX_+_78426469 0.76 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chrX_-_142722897 0.75 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr3_-_155011483 0.74 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr11_+_57308979 0.74 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr21_+_30673091 0.73 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_-_142224280 0.73 ENST00000390367.3
TRBV11-1
T cell receptor beta variable 11-1
chr19_-_44160768 0.73 ENST00000593447.1
PLAUR
plasminogen activator, urokinase receptor
chr1_+_167063282 0.72 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr7_+_142636603 0.72 ENST00000409607.3
C7orf34
chromosome 7 open reading frame 34
chr11_-_119991589 0.71 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr2_+_46706725 0.70 ENST00000434431.1
TMEM247
transmembrane protein 247
chr8_+_10530133 0.70 ENST00000304519.5
C8orf74
chromosome 8 open reading frame 74
chr7_-_142198049 0.70 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr10_+_120116527 0.70 ENST00000445161.1
LINC00867
long intergenic non-protein coding RNA 867
chr4_-_80329356 0.70 ENST00000358842.3
GK2
glycerol kinase 2
chr11_-_118083600 0.69 ENST00000524477.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr7_+_142636440 0.69 ENST00000458732.1
C7orf34
chromosome 7 open reading frame 34
chr2_+_3705785 0.68 ENST00000252505.3
ALLC
allantoicase
chr12_+_81110684 0.68 ENST00000228644.3
MYF5
myogenic factor 5
chr7_-_142162390 0.67 ENST00000390371.3
TRBV6-6
T cell receptor beta variable 6-6
chr16_+_31366536 0.66 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr2_+_169923504 0.66 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_159409512 0.65 ENST00000423932.3
OR10J1
olfactory receptor, family 10, subfamily J, member 1
chr19_-_51538118 0.65 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr12_+_100041527 0.64 ENST00000324341.1
FAM71C
family with sequence similarity 71, member C
chr16_-_52640834 0.64 ENST00000510238.3
CASC16
cancer susceptibility candidate 16 (non-protein coding)
chr3_+_107096188 0.64 ENST00000261058.1
CCDC54
coiled-coil domain containing 54
chrX_+_36065053 0.63 ENST00000313548.4
CHDC2
calponin homology domain containing 2
chr11_-_119247004 0.63 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr7_+_142353445 0.62 ENST00000390396.1
TRBV23-1
T cell receptor beta variable 23-1 (non-functional)
chr12_-_2113583 0.62 ENST00000397173.4
ENST00000280665.6
DCP1B
decapping mRNA 1B
chr10_+_69865866 0.62 ENST00000354393.2
MYPN
myopalladin
chr11_-_107729287 0.61 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr12_-_11002063 0.61 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr3_-_46786245 0.61 ENST00000442359.2
PRSS45
protease, serine, 45
chr1_+_179699318 0.60 ENST00000423879.1
RP11-12M5.1
RP11-12M5.1
chr7_-_142247606 0.59 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr16_+_21623958 0.58 ENST00000568826.1
METTL9
methyltransferase like 9
chrX_+_123480375 0.58 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr14_+_20295608 0.57 ENST00000568211.1
ENST00000315947.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr9_-_5084580 0.57 ENST00000601793.1
AL161450.1
Uncharacterized protein
chr1_-_106161540 0.57 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
RP11-251P6.1
chr11_+_35198243 0.57 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr11_+_35201826 0.57 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr6_+_47749718 0.56 ENST00000489301.2
ENST00000371211.2
ENST00000393699.2
OPN5
opsin 5
chr11_-_10920714 0.56 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr10_+_115511434 0.56 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chrX_+_123480194 0.56 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr10_+_5566916 0.55 ENST00000315238.1
CALML3
calmodulin-like 3
chrX_+_123480421 0.55 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr2_+_169923577 0.55 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_+_59480899 0.55 ENST00000300150.7
STX3
syntaxin 3
chr19_+_9361606 0.55 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr11_+_35198118 0.55 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr1_+_29241027 0.55 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr2_+_233271546 0.55 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr3_+_94657118 0.54 ENST00000466089.1
ENST00000470465.1
LINC00879
long intergenic non-protein coding RNA 879
chr1_-_92951607 0.54 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr13_+_76378305 0.54 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr15_+_86686953 0.54 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr16_-_46797149 0.54 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr14_+_22615942 0.54 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chrX_-_127186382 0.54 ENST00000371124.3
ACTRT1
actin-related protein T1
chr6_+_89790459 0.54 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_35222629 0.53 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr12_-_10324716 0.53 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr2_-_179567206 0.53 ENST00000414766.1
TTN
titin
chr9_-_97356075 0.53 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr21_+_39668831 0.53 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_86141245 0.53 ENST00000546501.1
RP11-219B4.5
Uncharacterized protein
chr14_+_22891362 0.53 ENST00000390469.2
TRDV2
T cell receptor delta variable 2
chrX_+_100224676 0.52 ENST00000450049.2
ARL13A
ADP-ribosylation factor-like 13A
chr1_-_158656488 0.52 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr9_+_1051481 0.52 ENST00000358146.2
ENST00000259622.6
DMRT2
doublesex and mab-3 related transcription factor 2
chr13_+_76378357 0.52 ENST00000489941.2
ENST00000525373.1
LMO7
LIM domain 7
chr9_+_33629119 0.51 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr9_-_127263265 0.51 ENST00000373587.3
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr12_-_8088871 0.51 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr1_+_207038699 0.51 ENST00000367098.1
IL20
interleukin 20
chr14_+_23004404 0.50 ENST00000390528.1
TRAJ9
T cell receptor alpha joining 9
chr14_-_22103096 0.50 ENST00000542433.1
OR10G2
olfactory receptor, family 10, subfamily G, member 2
chr12_-_54813229 0.50 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr2_+_219110149 0.50 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chrX_+_135279179 0.49 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr15_-_45406385 0.49 ENST00000389039.6
DUOX2
dual oxidase 2
chr6_-_133084564 0.49 ENST00000532012.1
VNN2
vanin 2
chr1_+_64669294 0.49 ENST00000371077.5
UBE2U
ubiquitin-conjugating enzyme E2U (putative)
chr14_+_22919081 0.49 ENST00000390473.1
TRDJ1
T cell receptor delta joining 1
chr7_-_148580563 0.48 ENST00000476773.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_14716606 0.48 ENST00000253697.3
ENST00000435614.1
ENST00000412910.1
C3orf20
chromosome 3 open reading frame 20
chr6_+_159071015 0.48 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr17_+_28268623 0.48 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr12_-_10151773 0.47 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr17_-_10372875 0.47 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr4_+_42895284 0.46 ENST00000399770.2
GRXCR1
glutaredoxin, cysteine rich 1
chr1_-_31661000 0.46 ENST00000263693.1
ENST00000398657.2
ENST00000526106.1
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr15_-_94614049 0.46 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
CTD-3049M7.1
chr4_-_123542224 0.46 ENST00000264497.3
IL21
interleukin 21
chr6_+_132455118 0.46 ENST00000458028.1
LINC01013
long intergenic non-protein coding RNA 1013
chr6_-_33297013 0.45 ENST00000453407.1
DAXX
death-domain associated protein
chr9_+_33638033 0.45 ENST00000390389.3
TRBV23OR9-2
T cell receptor beta variable 23/OR9-2 (non-functional)
chr15_+_28624878 0.45 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr17_-_49198216 0.45 ENST00000262013.7
ENST00000357122.4
SPAG9
sperm associated antigen 9
chr4_+_71108300 0.45 ENST00000304954.3
CSN3
casein kappa
chr6_-_43595039 0.45 ENST00000307114.7
GTPBP2
GTP binding protein 2
chr7_-_142099977 0.44 ENST00000390359.3
TRBV7-8
T cell receptor beta variable 7-8
chr14_+_22236722 0.44 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.5 1.8 GO:0051710 cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710)
0.4 1.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.3 1.7 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3 2.9 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3 1.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.3 1.5 GO:0007525 somatic muscle development(GO:0007525)
0.3 1.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.3 1.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 3.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.2 0.7 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 0.7 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.2 2.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 0.9 GO:0007343 egg activation(GO:0007343)
0.2 0.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.2 0.7 GO:0043605 cellular amide catabolic process(GO:0043605)
0.2 2.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.2 0.5 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.2 1.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.9 GO:0042335 cuticle development(GO:0042335)
0.1 1.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.5 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 2.9 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.4 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.1 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.1 GO:2000458 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.1 1.1 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 1.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.8 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 0.5 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0060278 regulation of ovulation(GO:0060278)
0.1 1.1 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.1 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.4 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.3 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.5 GO:0071461 cellular response to redox state(GO:0071461)
0.1 2.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.8 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.4 GO:0061055 myotome development(GO:0061055)
0.1 0.7 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.1 0.3 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.1 0.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 0.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.1 0.2 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.7 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.1 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0002260 lymphocyte homeostasis(GO:0002260) T cell homeostasis(GO:0043029)
0.0 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.3 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.4 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.5 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483) negative regulation of tooth mineralization(GO:0070171)
0.0 1.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 4.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 1.2 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 7.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245) positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 1.0 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.3 GO:0015846 polyamine transport(GO:0015846)
0.0 0.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 1.0 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.6 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 3.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.5 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 1.0 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.1 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 2.8 GO:0070268 cornification(GO:0070268)
0.0 0.9 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.2 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.2 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 1.2 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0019860 transformation of host cell by virus(GO:0019087) uracil metabolic process(GO:0019860)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.1 GO:0051693 actin filament capping(GO:0051693)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.6 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.3 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.8 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 1.8 GO:0051225 spindle assembly(GO:0051225)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.9 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.4 2.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 0.9 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.5 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 0.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.2 1.5 GO:0032010 phagolysosome(GO:0032010)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0001534 radial spoke(GO:0001534)
0.1 1.0 GO:0036128 CatSper complex(GO:0036128)
0.1 1.1 GO:0033503 HULC complex(GO:0033503)
0.1 1.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 1.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.5 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.3 GO:0031904 endosome lumen(GO:0031904)
0.0 3.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 1.8 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.0 GO:0097542 ciliary tip(GO:0097542)
0.0 0.7 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.4 0.4 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.3 0.9 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.3 1.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.3 0.8 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.7 GO:0004370 glycerol kinase activity(GO:0004370)
0.2 0.6 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.2 0.8 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 2.2 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.5 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 1.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 0.4 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.7 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 1.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 1.0 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.5 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.9 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0070728 leucine binding(GO:0070728)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.4 GO:0051373 FATZ binding(GO:0051373)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 1.4 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 1.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0031433 telethonin binding(GO:0031433)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 4.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.9 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 7.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.8 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 1.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 2.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 5.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME OPSINS Genes involved in Opsins
0.0 1.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 1.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 6.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 4.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 5.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition