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Illumina Body Map 2: averaged replicates

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Results for NFIA

Z-value: 2.69

Motif logo

Transcription factors associated with NFIA

Gene Symbol Gene ID Gene Info
ENSG00000162599.11 NFIA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFIAhg19_v2_chr1_+_61330931_613310170.584.5e-04Click!

Activity profile of NFIA motif

Sorted Z-values of NFIA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFIA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_10421853 12.82 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr17_-_10452929 7.62 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr1_-_26394114 7.14 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr10_+_24528108 6.83 ENST00000438429.1
KIAA1217
KIAA1217
chrX_+_105445717 5.75 ENST00000372552.1
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr4_-_111558135 5.18 ENST00000394598.2
ENST00000394595.3
PITX2
paired-like homeodomain 2
chr17_-_10372875 4.76 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr1_+_145413268 4.48 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2
hemochromatosis type 2 (juvenile)
chr3_-_52488048 4.42 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr4_-_44653636 4.41 ENST00000415895.4
ENST00000332990.5
YIPF7
Yip1 domain family, member 7
chr13_+_23755054 4.21 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr13_+_23755099 4.20 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr3_-_155011483 3.99 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr13_+_23755127 3.97 ENST00000545013.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_+_160160346 3.69 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr6_+_123100620 3.67 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr1_+_160160283 3.65 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_69171739 3.47 ENST00000489031.1
LMOD3
leiomodin 3 (fetal)
chr10_+_24755416 3.43 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr20_+_30407105 3.42 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chrX_-_15332665 3.36 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr20_+_30407151 3.30 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr1_+_44889697 3.30 ENST00000443020.2
RNF220
ring finger protein 220
chr6_-_123958141 3.16 ENST00000334268.4
TRDN
triadin
chr17_-_15168624 3.12 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22
peripheral myelin protein 22
chr16_+_30383613 3.02 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_+_71944241 3.00 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr11_+_77774897 2.91 ENST00000281030.2
THRSP
thyroid hormone responsive
chr8_+_67344710 2.88 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr3_+_148508845 2.82 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr16_+_6533729 2.82 ENST00000551752.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_201081579 2.75 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr5_+_53751445 2.66 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr14_-_61124977 2.66 ENST00000554986.1
SIX1
SIX homeobox 1
chr9_-_129884902 2.61 ENST00000373417.1
ANGPTL2
angiopoietin-like 2
chr1_+_201159914 2.60 ENST00000335211.4
ENST00000451870.2
ENST00000295591.8
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr9_-_129885010 2.59 ENST00000373425.3
ANGPTL2
angiopoietin-like 2
chr20_+_43343476 2.57 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr3_+_16216137 2.55 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr10_+_115312766 2.53 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr6_-_76072719 2.49 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr6_-_123957942 2.48 ENST00000398178.3
TRDN
triadin
chr2_-_227050079 2.46 ENST00000423838.1
AC068138.1
AC068138.1
chr7_-_56160625 2.44 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr4_-_54518619 2.43 ENST00000507168.1
ENST00000510143.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr10_+_5005598 2.40 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr17_-_10325261 2.40 ENST00000403437.2
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr17_+_68100989 2.39 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_-_111358372 2.37 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr15_+_63050785 2.35 ENST00000472902.1
TLN2
talin 2
chr20_+_43343886 2.34 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chrX_+_135252050 2.30 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr5_+_36606992 2.29 ENST00000505202.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_135251783 2.27 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr3_-_47950745 2.21 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr1_-_9563433 2.18 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr6_-_123958051 2.18 ENST00000546248.1
TRDN
triadin
chr18_-_53089538 2.18 ENST00000566777.1
TCF4
transcription factor 4
chr17_-_67224812 2.17 ENST00000423818.2
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chrX_+_135251835 2.10 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr13_-_36050819 2.10 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr11_+_118477144 2.07 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr2_+_173955327 2.07 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr5_+_42423872 2.05 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr20_+_43343517 2.03 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr17_-_53809473 2.01 ENST00000575734.1
TMEM100
transmembrane protein 100
chr8_+_145729465 2.00 ENST00000394955.2
GPT
glutamic-pyruvate transaminase (alanine aminotransferase)
chr14_+_77582905 2.00 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr18_+_59000815 1.98 ENST00000262717.4
CDH20
cadherin 20, type 2
chr15_-_35088340 1.98 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chr16_-_10652993 1.97 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr4_-_187517928 1.97 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr5_+_36606700 1.95 ENST00000416645.2
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_216896780 1.95 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG
estrogen-related receptor gamma
chr2_-_99485825 1.94 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr12_-_70093065 1.93 ENST00000553096.1
BEST3
bestrophin 3
chr6_-_123958111 1.93 ENST00000542443.1
TRDN
triadin
chr1_-_203144941 1.93 ENST00000255416.4
MYBPH
myosin binding protein H
chr7_-_56160666 1.93 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr1_-_209792111 1.92 ENST00000455193.1
LAMB3
laminin, beta 3
chr11_-_13517565 1.92 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr11_-_35547151 1.91 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr4_+_41362796 1.91 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr18_+_29171689 1.89 ENST00000237014.3
TTR
transthyretin
chr9_-_34589734 1.88 ENST00000378980.3
CNTFR
ciliary neurotrophic factor receptor
chr12_-_70093111 1.87 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr8_-_42358742 1.86 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr10_-_61122220 1.85 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr9_-_34590121 1.84 ENST00000417345.1
CNTFR
ciliary neurotrophic factor receptor
chr9_-_34589700 1.83 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr2_-_163099885 1.81 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr5_+_36608422 1.79 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_-_42947121 1.78 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chr14_-_75079294 1.77 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr7_-_99381884 1.75 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr3_+_16216210 1.74 ENST00000437509.1
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr1_-_91317072 1.72 ENST00000435649.2
ENST00000443802.1
RP4-665J23.1
RP4-665J23.1
chr11_-_61348292 1.70 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7
synaptotagmin VII
chr11_+_27062860 1.69 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_+_109685630 1.69 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr12_-_52911718 1.68 ENST00000548409.1
KRT5
keratin 5
chr1_-_203320617 1.68 ENST00000354955.4
FMOD
fibromodulin
chr10_-_61469837 1.66 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr3_+_148447887 1.64 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr17_-_74533734 1.64 ENST00000589342.1
CYGB
cytoglobin
chr2_-_218770168 1.63 ENST00000413554.1
TNS1
tensin 1
chr12_-_47226152 1.62 ENST00000546940.1
SLC38A4
solute carrier family 38, member 4
chr12_+_56114151 1.61 ENST00000547072.1
ENST00000552930.1
ENST00000257895.5
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr11_-_16430399 1.61 ENST00000528252.1
SOX6
SRY (sex determining region Y)-box 6
chr12_+_7169887 1.61 ENST00000542978.1
C1S
complement component 1, s subcomponent
chr2_-_163100045 1.60 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr1_+_170632250 1.60 ENST00000367760.3
PRRX1
paired related homeobox 1
chr21_+_35552978 1.60 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr10_+_102106829 1.60 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr4_+_113739244 1.60 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr3_+_69812701 1.59 ENST00000472437.1
MITF
microphthalmia-associated transcription factor
chr12_+_56114189 1.59 ENST00000548082.1
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr19_+_41725140 1.59 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr17_-_39661849 1.58 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr12_-_70093162 1.58 ENST00000551160.1
BEST3
bestrophin 3
chr1_+_59250815 1.58 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr1_-_21978312 1.56 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr11_-_2170786 1.56 ENST00000300632.5
IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_87286997 1.55 ENST00000395866.2
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr10_+_5238793 1.55 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr3_-_52002403 1.54 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr7_+_153749732 1.54 ENST00000377770.3
DPP6
dipeptidyl-peptidase 6
chr12_-_15038779 1.54 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr13_+_31480328 1.53 ENST00000380482.4
MEDAG
mesenteric estrogen-dependent adipogenesis
chr12_+_110718428 1.51 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr3_-_52002194 1.51 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr7_+_95115210 1.48 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr19_+_49259325 1.46 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr17_-_39769005 1.46 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr17_-_67057203 1.46 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_163099546 1.46 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr10_+_95848824 1.44 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr18_+_61143994 1.44 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr1_-_36906474 1.44 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr14_+_91581011 1.41 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr10_-_104597286 1.40 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr15_-_93632421 1.39 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr2_+_189839046 1.39 ENST00000304636.3
ENST00000317840.5
COL3A1
collagen, type III, alpha 1
chr9_+_470288 1.39 ENST00000382303.1
KANK1
KN motif and ankyrin repeat domains 1
chr17_-_67057114 1.38 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr3_+_35680339 1.38 ENST00000450234.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr17_+_68101117 1.37 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr11_+_60997055 1.36 ENST00000544899.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr17_-_74533963 1.35 ENST00000293230.5
CYGB
cytoglobin
chr17_-_39661947 1.35 ENST00000590425.1
KRT13
keratin 13
chrX_+_125953746 1.35 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr10_-_21463116 1.35 ENST00000417816.2
NEBL
nebulette
chr5_+_36608280 1.34 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr11_-_118023490 1.33 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chrX_-_84363974 1.33 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr11_-_66675371 1.32 ENST00000393955.2
PC
pyruvate carboxylase
chr1_-_41950342 1.32 ENST00000372587.4
EDN2
endothelin 2
chr6_-_127840048 1.32 ENST00000467753.1
SOGA3
SOGA family member 3
chr2_-_111291587 1.31 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr22_-_38539185 1.31 ENST00000452542.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr14_-_75078725 1.31 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr1_-_237167718 1.30 ENST00000464121.2
MT1HL1
metallothionein 1H-like 1
chr17_+_37784749 1.30 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr13_-_36705425 1.29 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr1_-_217250231 1.29 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr3_+_119013185 1.29 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr2_-_31637560 1.28 ENST00000379416.3
XDH
xanthine dehydrogenase
chr15_+_67458357 1.28 ENST00000537194.2
SMAD3
SMAD family member 3
chr1_+_46379254 1.27 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr5_-_150727111 1.26 ENST00000335244.4
ENST00000521967.1
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr17_+_67957878 1.26 ENST00000420427.1
AC004562.1
AC004562.1
chr11_+_10326612 1.26 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr3_-_24536222 1.25 ENST00000415021.1
ENST00000447875.1
THRB
thyroid hormone receptor, beta
chr12_+_57828521 1.25 ENST00000309668.2
INHBC
inhibin, beta C
chr1_-_217262933 1.24 ENST00000359162.2
ESRRG
estrogen-related receptor gamma
chr7_+_66800928 1.24 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr18_+_43913919 1.24 ENST00000587853.1
RNF165
ring finger protein 165
chr3_-_24536253 1.23 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB
thyroid hormone receptor, beta
chr12_-_53207842 1.21 ENST00000458244.2
KRT4
keratin 4
chr2_+_17721230 1.21 ENST00000457525.1
VSNL1
visinin-like 1
chr9_+_35806082 1.20 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr8_+_97597148 1.19 ENST00000521590.1
SDC2
syndecan 2
chr19_+_42254885 1.19 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chrX_-_138287168 1.19 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr11_-_26593649 1.18 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr18_-_47792851 1.18 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr4_-_87770416 1.18 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr1_-_120311517 1.18 ENST00000369406.3
ENST00000544913.2
HMGCS2
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
chr5_-_36301984 1.17 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr10_-_101190202 1.17 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chr1_-_72748140 1.16 ENST00000434200.1
NEGR1
neuronal growth regulator 1
chr22_-_24989014 1.16 ENST00000318753.8
FAM211B
family with sequence similarity 211, member B
chrX_+_103031758 1.15 ENST00000303958.2
ENST00000361621.2
PLP1
proteolipid protein 1
chrX_-_106146547 1.15 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr3_+_159570722 1.14 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_+_241938255 1.13 ENST00000401884.1
ENST00000405547.3
ENST00000310397.8
ENST00000342631.6
SNED1
sushi, nidogen and EGF-like domains 1
chr22_-_38539487 1.13 ENST00000498338.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr7_+_94537542 1.13 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr12_-_28125638 1.13 ENST00000545234.1
PTHLH
parathyroid hormone-like hormone
chr16_+_82090028 1.12 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.7 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
1.6 4.9 GO:1902362 melanocyte apoptotic process(GO:1902362)
1.6 11.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
1.4 7.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.0 5.2 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
1.0 2.9 GO:0015993 molecular hydrogen transport(GO:0015993)
0.8 2.5 GO:1904640 response to methionine(GO:1904640)
0.8 3.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.7 7.4 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.7 2.7 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.7 2.6 GO:0009822 alkaloid catabolic process(GO:0009822)
0.6 1.9 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.6 7.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 1.6 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.5 7.6 GO:0001778 plasma membrane repair(GO:0001778)
0.5 4.3 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.5 1.6 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.5 1.6 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.5 5.6 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.5 1.5 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.5 2.0 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.5 2.5 GO:0008050 female courtship behavior(GO:0008050)
0.5 6.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.5 1.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.5 3.2 GO:0051012 microtubule sliding(GO:0051012)
0.4 1.3 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.4 1.3 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.4 3.0 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.4 1.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.4 1.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.4 1.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 0.4 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 1.2 GO:0006106 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.4 1.9 GO:0033292 T-tubule organization(GO:0033292) protein localization to T-tubule(GO:0036371)
0.4 8.9 GO:2001212 regulation of vasculogenesis(GO:2001212)
0.3 1.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 1.7 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.3 0.7 GO:0061056 sclerotome development(GO:0061056)
0.3 1.3 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 2.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.3 0.6 GO:0006090 pyruvate metabolic process(GO:0006090)
0.3 2.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.3 2.4 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.3 0.9 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.3 1.6 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.3 1.8 GO:0006740 NADPH regeneration(GO:0006740)
0.2 2.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 1.5 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 1.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 1.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.7 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 0.7 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.2 2.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 1.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 5.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 2.9 GO:0043587 tongue morphogenesis(GO:0043587)
0.2 0.8 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.2 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 1.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.8 GO:0048631 negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.2 0.8 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.2 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 4.5 GO:0016540 protein autoprocessing(GO:0016540)
0.2 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.9 GO:0001757 somite specification(GO:0001757)
0.2 0.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 0.5 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.2 1.2 GO:0008218 bioluminescence(GO:0008218)
0.2 2.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.3 GO:0021564 vagus nerve development(GO:0021564)
0.2 1.0 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.5 GO:2001112 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.2 2.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 3.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.6 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.3 GO:0051552 flavone metabolic process(GO:0051552)
0.1 3.1 GO:0032060 bleb assembly(GO:0032060)
0.1 1.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.8 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 1.7 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 1.3 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.7 GO:0060467 negative regulation of fertilization(GO:0060467)
0.1 1.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 1.4 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.1 1.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.1 0.7 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0001575 globoside metabolic process(GO:0001575)
0.1 1.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 4.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 7.5 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.6 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 2.1 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.0 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 1.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 3.1 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.9 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 1.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.7 GO:1902896 terminal web assembly(GO:1902896)
0.1 2.0 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 6.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.1 1.3 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.4 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.9 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 2.0 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 1.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 4.4 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 2.0 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 1.9 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 2.9 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 0.6 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 1.2 GO:1902224 ketone body metabolic process(GO:1902224)
0.1 6.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.5 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:0099545 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.1 0.8 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 3.2 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0042746 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.1 0.3 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.4 GO:1901880 negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein complex disassembly(GO:0043242) negative regulation of protein depolymerization(GO:1901880)
0.1 1.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.0 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.2 GO:0072553 terminal button organization(GO:0072553)
0.1 3.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.4 GO:0033762 response to glucagon(GO:0033762) cellular response to glucagon stimulus(GO:0071377)
0.1 0.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 3.8 GO:0010107 potassium ion import(GO:0010107)
0.1 0.5 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.7 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.7 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 0.5 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.8 GO:0019532 oxalate transport(GO:0019532)
0.1 1.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 1.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 1.0 GO:0009642 response to light intensity(GO:0009642)
0.0 5.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.6 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 12.9 GO:0006936 muscle contraction(GO:0006936)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 1.3 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 1.0 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.0 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.9 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.6 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 2.4 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 2.0 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 2.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0071639 positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.0 0.3 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.7 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 2.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0051808 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 7.3 GO:0060047 heart contraction(GO:0060047)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.7 GO:0097435 fibril organization(GO:0097435)
0.0 0.4 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.6 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 1.2 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.4 GO:0075522 IRES-dependent translational initiation(GO:0002192) IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585) positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 1.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 1.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.5 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 3.6 GO:0043271 negative regulation of ion transport(GO:0043271)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 1.6 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.7 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 3.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 2.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.5 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.3 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 3.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0010039 response to iron ion(GO:0010039)
0.0 0.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:0019915 lipid storage(GO:0019915)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0071158 positive regulation of cell cycle arrest(GO:0071158)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 1.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.3 GO:0051168 nuclear export(GO:0051168)
0.0 0.2 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 1.2 GO:0010976 positive regulation of neuron projection development(GO:0010976)
0.0 0.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.7 GO:0010507 negative regulation of autophagy(GO:0010507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.4 GO:0016012 sarcoglycan complex(GO:0016012)
1.1 5.6 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.1 17.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.0 7.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.8 22.8 GO:0032982 myosin filament(GO:0032982)
0.7 4.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.7 2.0 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 4.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 2.5 GO:0044308 axonal spine(GO:0044308)
0.4 2.0 GO:0042643 actomyosin, actin portion(GO:0042643)
0.3 1.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.3 1.9 GO:0031673 H zone(GO:0031673)
0.3 4.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.3 4.9 GO:0071438 invadopodium membrane(GO:0071438)
0.2 12.9 GO:0031430 M band(GO:0031430)
0.2 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.2 3.0 GO:0005859 muscle myosin complex(GO:0005859)
0.2 0.6 GO:0036457 keratohyalin granule(GO:0036457)
0.2 1.7 GO:0044326 dendritic spine neck(GO:0044326)
0.2 0.8 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.2 1.9 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.7 GO:0032009 early phagosome(GO:0032009)
0.1 2.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 4.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.1 0.7 GO:1990357 terminal web(GO:1990357)
0.1 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 1.5 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.5 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.7 GO:0001652 granular component(GO:0001652)
0.1 1.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.1 GO:0033643 host cell part(GO:0033643)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 2.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.1 GO:0043218 compact myelin(GO:0043218)
0.1 2.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.3 GO:0005602 complement component C1 complex(GO:0005602)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.6 GO:0030315 T-tubule(GO:0030315)
0.1 5.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 3.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 4.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 19.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 4.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 6.8 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.0 GO:0099738 cell cortex region(GO:0099738)
0.0 1.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.7 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 7.8 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 2.2 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 5.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 11.3 GO:0044297 cell body(GO:0044297)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)
0.0 8.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.2 GO:0031526 brush border membrane(GO:0031526)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.7 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.8 6.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.7 3.0 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.7 7.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 2.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.7 2.6 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.7 6.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 1.8 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.6 4.5 GO:0098821 BMP receptor activity(GO:0098821)
0.6 5.6 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.5 1.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 1.5 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.5 3.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.4 1.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.4 4.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 1.7 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 1.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 4.4 GO:0031013 troponin I binding(GO:0031013)
0.4 1.2 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 16.1 GO:0000146 microfilament motor activity(GO:0000146)
0.3 4.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.3 1.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.3 1.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 2.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 7.1 GO:0031432 titin binding(GO:0031432)
0.3 1.1 GO:0030305 heparanase activity(GO:0030305)
0.3 1.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.3 1.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.3 1.6 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 2.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 2.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.0 GO:0016499 orexin receptor activity(GO:0016499)
0.2 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 4.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 6.3 GO:0005523 tropomyosin binding(GO:0005523)
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 2.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 7.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.2 0.8 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 0.7 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 1.6 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 3.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 7.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 5.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.6 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.2 3.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 2.4 GO:0047499 ATP-dependent protein binding(GO:0043008) calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.8 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 1.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.3 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 2.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 4.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 4.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.8 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 2.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 2.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.9 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.4 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056)
0.1 0.6 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 0.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 2.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.1 14.4 GO:0044325 ion channel binding(GO:0044325)
0.1 1.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 2.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 4.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 10.0 GO:0003774 motor activity(GO:0003774)
0.1 0.2 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 2.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 3.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 2.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0030275 LRR domain binding(GO:0030275)
0.0 1.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 6.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.5 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 3.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 2.0 GO:0017022 myosin binding(GO:0017022)
0.0 2.7 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 4.8 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.2 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 2.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 6.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.8 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 2.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 17.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 5.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 3.2 PID BMP PATHWAY BMP receptor signaling
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 3.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.6 PID FOXO PATHWAY FoxO family signaling
0.0 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 4.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.4 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 2.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 3.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 12.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 3.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 3.0 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 4.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 1.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 9.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.8 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 1.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 10.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 9.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 2.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 6.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 4.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 1.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.8 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 16.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 2.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 4.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism