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Illumina Body Map 2: averaged replicates
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Results for NFIL3
Z-value: 1.44
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Transcription factors associated with NFIL3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIL3 | hg19_v2_chr9_-_94186131_94186174 | 0.02 | 9.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_69962185 Show fit | 5.32 |
ENST00000305231.7
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
| chr4_+_69962212 Show fit | 4.94 |
ENST00000508661.1
|
UDP glucuronosyltransferase 2 family, polypeptide B7 |
|
| chr4_+_69681710 Show fit | 4.00 |
ENST00000265403.7
ENST00000458688.2 |
UDP glucuronosyltransferase 2 family, polypeptide B10 |
|
| chr2_+_102928009 Show fit | 3.56 |
ENST00000404917.2
ENST00000447231.1 |
interleukin 1 receptor-like 1 |
|
| chr3_+_186383741 Show fit | 2.90 |
ENST00000232003.4
|
histidine-rich glycoprotein |
|
| chr4_+_155484103 Show fit | 2.87 |
ENST00000302068.4
|
fibrinogen beta chain |
|
| chr9_-_104198042 Show fit | 2.41 |
ENST00000374855.4
|
aldolase B, fructose-bisphosphate |
|
| chr3_+_186435137 Show fit | 2.31 |
ENST00000447445.1
|
kininogen 1 |
|
| chr11_-_14993819 Show fit | 2.19 |
ENST00000396372.2
ENST00000361010.3 ENST00000359642.3 ENST00000331587.4 |
calcitonin-related polypeptide alpha |
|
| chr4_+_104346194 Show fit | 2.17 |
ENST00000510200.1
|
RP11-328K4.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NFIL3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 15.4 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 6.6 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.8 | 5.8 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.4 | 5.6 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.2 | 5.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 5.2 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.3 | 4.5 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 1.3 | 4.0 | GO:0019836 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
| 0.1 | 4.0 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.8 | 3.8 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 26.4 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 12.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.2 | 11.1 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 10.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.5 | 7.0 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 4.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.4 | 4.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.5 | 3.9 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.0 | 3.8 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 3.8 | GO:0016605 | PML body(GO:0016605) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 24.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.3 | 6.7 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 1.9 | 5.8 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.0 | 5.7 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 4.7 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.0 | 4.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.3 | 3.5 | GO:0004321 | fatty-acyl-CoA synthase activity(GO:0004321) |
| 0.1 | 3.4 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
| 0.2 | 3.2 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
| 0.1 | 3.2 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.4 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.1 | 6.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 2.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.5 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 2.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 2.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.0 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 1.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.9 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 18.7 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 8.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.3 | 7.2 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 6.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.3 | 5.4 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.3 | 5.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 5.3 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 4.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 4.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.2 | 3.7 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |