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Illumina Body Map 2: averaged replicates

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Results for NFKB1

Z-value: 2.52

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
ENSG00000109320.7 NFKB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103422499_1034226320.655.0e-05Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_219745020 8.10 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr6_-_31550192 6.62 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr19_+_42381173 6.56 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr6_+_31540056 6.10 ENST00000418386.2
LTA
lymphotoxin alpha
chr19_+_17638059 5.82 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr19_+_42381337 5.77 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr22_-_37640277 5.66 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_-_202130702 5.47 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr22_-_37640456 5.40 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_50730910 5.30 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr5_+_35852797 5.25 ENST00000508941.1
IL7R
interleukin 7 receptor
chr17_-_61776522 5.17 ENST00000582055.1
LIMD2
LIM domain containing 2
chr19_+_17638041 5.12 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr12_-_55375622 4.96 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr14_+_22573582 4.47 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr9_-_139927462 4.39 ENST00000314412.6
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr12_-_58131931 4.39 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr17_-_61777090 4.28 ENST00000578061.1
LIMD2
LIM domain containing 2
chr19_+_1067271 4.19 ENST00000536472.1
ENST00000590214.1
HMHA1
histocompatibility (minor) HA-1
chr4_-_74864386 4.05 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr12_-_9913489 4.01 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr3_-_111852061 4.00 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr11_+_128562372 3.94 ENST00000344954.6
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_+_102188224 3.90 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr19_+_1067144 3.90 ENST00000313093.2
HMHA1
histocompatibility (minor) HA-1
chr4_+_74735102 3.89 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_+_143013198 3.81 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr22_+_37318082 3.76 ENST00000406230.1
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr19_+_1067492 3.71 ENST00000586866.1
HMHA1
histocompatibility (minor) HA-1
chr1_-_186649543 3.70 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_202129105 3.69 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_+_45504688 3.61 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr6_+_106534192 3.52 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr5_-_149792295 3.50 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_+_75988851 3.44 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr16_+_3096638 3.43 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr3_-_111852128 3.38 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr4_-_185395191 3.28 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr11_+_102188272 3.27 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr9_+_82188077 3.24 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr20_-_50159198 3.24 ENST00000371564.3
ENST00000396009.3
ENST00000610033.1
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_-_54784353 3.23 ENST00000391746.1
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr14_+_52313833 3.17 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr9_-_136344197 3.17 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr19_+_50922187 3.09 ENST00000595883.1
ENST00000597855.1
ENST00000596074.1
ENST00000439922.2
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_+_111770278 3.09 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr1_-_202129704 3.08 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr22_+_27053422 3.08 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr5_+_82767284 3.07 ENST00000265077.3
VCAN
versican
chr19_-_6591113 3.05 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr14_-_70655684 3.03 ENST00000356921.2
ENST00000381269.2
ENST00000357887.3
SLC8A3
solute carrier family 8 (sodium/calcium exchanger), member 3
chr12_-_57023995 3.02 ENST00000549884.1
ENST00000546695.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr7_+_120969045 2.99 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr16_+_50775971 2.96 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr9_+_82187487 2.96 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr14_-_51297837 2.94 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chr16_+_50776021 2.91 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr6_+_32605134 2.91 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr10_+_104154229 2.86 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_-_17958771 2.85 ENST00000534444.1
JAK3
Janus kinase 3
chr14_+_61789382 2.83 ENST00000555082.1
PRKCH
protein kinase C, eta
chr22_+_27053567 2.83 ENST00000449717.1
ENST00000453023.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr16_+_50775948 2.81 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr14_-_51297360 2.80 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr22_+_27053190 2.77 ENST00000439738.1
ENST00000422403.1
ENST00000436238.1
ENST00000425476.1
ENST00000455640.1
ENST00000451141.1
ENST00000452429.1
ENST00000423278.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chrX_-_30595959 2.73 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr9_+_82187630 2.73 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr6_+_138188351 2.68 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr10_+_99609996 2.61 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr2_+_74212073 2.60 ENST00000441217.1
AC073046.25
AC073046.25
chr22_-_39151434 2.54 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr19_+_496454 2.53 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr14_-_51297197 2.50 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr14_+_75988768 2.49 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr14_-_103589246 2.49 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr1_+_156123318 2.47 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_+_111770294 2.47 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chr1_+_156123359 2.44 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_-_32821599 2.42 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr15_-_89438742 2.42 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr4_-_76944621 2.42 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr2_+_61108771 2.41 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr19_-_47734448 2.37 ENST00000439096.2
BBC3
BCL2 binding component 3
chr11_+_118754475 2.34 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr13_+_108922228 2.34 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr1_-_236030216 2.32 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr6_+_32605195 2.30 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_-_17958832 2.28 ENST00000458235.1
JAK3
Janus kinase 3
chr11_-_75062730 2.20 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr13_+_108921977 2.19 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr6_+_29691198 2.16 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691056 2.14 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr1_+_111770232 2.14 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr11_-_77185094 2.14 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr4_-_185395672 2.14 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr6_+_138188378 2.12 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr17_+_40440481 2.12 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr1_-_8000872 2.12 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_-_206671061 2.07 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr11_-_46142505 2.05 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr15_+_85923797 2.05 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chrX_-_21676442 2.02 ENST00000379499.2
KLHL34
kelch-like family member 34
chr2_-_191885686 2.01 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_37940153 1.99 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr14_+_96342729 1.99 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr1_+_100818009 1.98 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr1_+_89990378 1.98 ENST00000449440.1
LRRC8B
leucine rich repeat containing 8 family, member B
chr19_+_42364460 1.96 ENST00000593863.1
RPS19
ribosomal protein S19
chr6_+_138188551 1.94 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr7_-_102252589 1.90 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr20_-_60294804 1.89 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr4_-_122148620 1.89 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr1_-_155959853 1.87 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr22_-_39151995 1.86 ENST00000405018.1
ENST00000438058.1
SUN2
Sad1 and UNC84 domain containing 2
chr11_-_3862206 1.86 ENST00000351018.4
RHOG
ras homolog family member G
chr19_+_35485682 1.85 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr19_-_51920873 1.85 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr11_-_46142948 1.84 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr15_+_85923856 1.82 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr17_-_7108436 1.81 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr12_-_25403737 1.81 ENST00000256078.4
ENST00000556131.1
ENST00000311936.3
ENST00000557334.1
KRAS
Kirsten rat sarcoma viral oncogene homolog
chr11_-_75062829 1.80 ENST00000393505.4
ARRB1
arrestin, beta 1
chr2_+_208394616 1.80 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr17_+_40440094 1.79 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr17_-_4852332 1.78 ENST00000572383.1
PFN1
profilin 1
chr3_+_52280173 1.76 ENST00000296487.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr1_+_28285973 1.76 ENST00000373884.5
XKR8
XK, Kell blood group complex subunit-related family, member 8
chr12_+_56732658 1.76 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr6_+_32821924 1.74 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr1_+_26872324 1.74 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_-_40324255 1.71 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr22_-_39151947 1.71 ENST00000216064.4
SUN2
Sad1 and UNC84 domain containing 2
chr1_+_100818156 1.70 ENST00000336454.3
CDC14A
cell division cycle 14A
chr9_+_134103496 1.70 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr11_-_47400062 1.70 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr14_+_96343100 1.68 ENST00000503525.2
LINC00617
long intergenic non-protein coding RNA 617
chr20_+_57430162 1.68 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS
GNAS complex locus
chr19_-_51920952 1.67 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr6_-_44233361 1.66 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr2_+_163175394 1.66 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr19_+_35940486 1.66 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr2_+_208394455 1.62 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr3_+_52280220 1.61 ENST00000409502.3
ENST00000323588.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr19_+_51728316 1.60 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr10_-_73533255 1.59 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr11_-_46142615 1.58 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr16_+_85936295 1.58 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chrX_+_109245863 1.57 ENST00000372072.3
TMEM164
transmembrane protein 164
chr19_-_51920835 1.56 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr11_-_47399942 1.54 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr17_+_7590734 1.53 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr4_+_103422499 1.52 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr3_-_156878482 1.51 ENST00000295925.4
CCNL1
cyclin L1
chr18_-_28742813 1.51 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr2_+_61108650 1.50 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr14_-_35873856 1.50 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr3_+_52279737 1.49 ENST00000457351.2
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr7_+_69064300 1.49 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr6_+_14117872 1.48 ENST00000379153.3
CD83
CD83 molecule
chr8_-_130951940 1.47 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B
family with sequence similarity 49, member B
chr1_+_89990431 1.47 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr11_+_72525353 1.47 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr6_+_33378517 1.45 ENST00000428274.1
PHF1
PHD finger protein 1
chr5_+_159895275 1.44 ENST00000517927.1
MIR146A
microRNA 146a
chr6_+_29910301 1.44 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr22_+_27053545 1.43 ENST00000458302.1
ENST00000419237.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr11_-_47400078 1.42 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr6_-_111804905 1.41 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr20_+_9494987 1.41 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr3_+_52279902 1.40 ENST00000457454.1
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr1_-_155658085 1.40 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr2_-_240230890 1.39 ENST00000446876.1
HDAC4
histone deacetylase 4
chr21_+_34775772 1.39 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_-_4831701 1.38 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr6_+_18155632 1.38 ENST00000297792.5
KDM1B
lysine (K)-specific demethylase 1B
chr9_-_125667494 1.38 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chr17_+_46189311 1.37 ENST00000582481.1
SNX11
sorting nexin 11
chr6_+_144471643 1.36 ENST00000367568.4
STX11
syntaxin 11
chr14_+_64970427 1.35 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr12_-_54813229 1.33 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_+_34775698 1.32 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_42364313 1.31 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr11_-_72853267 1.31 ENST00000409418.4
FCHSD2
FCH and double SH3 domains 2
chr1_+_10093188 1.31 ENST00000377153.1
UBE4B
ubiquitination factor E4B
chr3_+_57261859 1.31 ENST00000495803.1
ENST00000444459.1
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr10_+_12391685 1.31 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr10_+_30723045 1.30 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr17_+_38465441 1.30 ENST00000577646.1
ENST00000254066.5
RARA
retinoic acid receptor, alpha
chr10_+_12391481 1.29 ENST00000378847.3
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr4_-_140098339 1.27 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr4_+_142557717 1.26 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr16_+_6069072 1.25 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_+_101546827 1.25 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_-_12849073 1.25 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chr5_-_150466692 1.25 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr10_-_6104253 1.23 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr2_+_112895939 1.23 ENST00000331203.2
ENST00000409903.1
ENST00000409667.3
ENST00000409450.3
FBLN7
fibulin 7
chr9_-_125667618 1.23 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr17_-_7154984 1.22 ENST00000574322.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr14_+_103243813 1.22 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:1990108 protein linear deubiquitination(GO:1990108)
2.7 8.2 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
2.2 6.7 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
2.0 6.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
1.7 5.1 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
1.5 4.4 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.3 5.3 GO:1902523 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) positive regulation of protein K63-linked ubiquitination(GO:1902523)
1.2 3.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.2 3.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
1.2 3.5 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.2 5.8 GO:0044027 hypermethylation of CpG island(GO:0044027)
1.1 3.4 GO:0045062 extrathymic T cell selection(GO:0045062)
1.1 2.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
1.0 4.2 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.0 11.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
1.0 3.8 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.9 7.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.9 4.5 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.8 2.3 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.8 3.8 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.8 16.8 GO:0048535 lymph node development(GO:0048535)
0.8 3.8 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.7 7.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.7 5.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.7 4.8 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.7 6.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.7 3.3 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.7 2.0 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.7 6.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.6 3.9 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.6 2.5 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.6 2.4 GO:0046967 cytosol to ER transport(GO:0046967)
0.6 1.8 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.6 1.8 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.6 3.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.6 1.7 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.6 2.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.5 8.1 GO:0048733 sebaceous gland development(GO:0048733)
0.5 1.5 GO:0032203 telomere formation via telomerase(GO:0032203)
0.5 2.0 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.5 1.5 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.5 4.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.5 2.7 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.4 7.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 7.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 3.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.4 3.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.4 8.9 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.3 3.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 3.0 GO:1990034 calcium ion export from cell(GO:1990034)
0.3 4.0 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.3 1.6 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.3 1.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 3.7 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.3 0.8 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.3 3.4 GO:0060022 hard palate development(GO:0060022)
0.3 1.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.5 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 2.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2 1.4 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.6 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 4.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 3.0 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 2.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.2 2.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.2 2.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 2.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 2.1 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 0.2 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.2 1.4 GO:0045350 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 3.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.8 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.2 0.8 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 1.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 5.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.2 0.9 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 1.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.2 1.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.3 GO:1990619 histone H3-K9 deacetylation(GO:1990619)
0.2 1.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 1.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 0.6 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 3.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.1 3.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 3.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 3.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 3.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 0.8 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 8.9 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 2.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 1.7 GO:0042940 D-amino acid transport(GO:0042940)
0.1 14.1 GO:0042100 B cell proliferation(GO:0042100)
0.1 3.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.4 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.8 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 1.6 GO:0042832 defense response to protozoan(GO:0042832)
0.1 0.9 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 2.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 3.6 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.2 GO:0014858 positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.4 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 1.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:0072553 terminal button organization(GO:0072553)
0.1 2.5 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.1 1.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 3.1 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 13.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 3.2 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 8.6 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 1.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 1.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 1.4 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 3.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.3 GO:0048840 otolith development(GO:0048840)
0.1 1.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 1.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 3.6 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 2.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 1.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 2.2 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.7 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 1.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 5.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 2.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 3.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.9 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 2.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 1.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.9 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 6.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.4 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 4.6 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.0 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.8 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 1.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.6 GO:0006814 sodium ion transport(GO:0006814)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.7 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.2 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.9 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 1.0 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 2.5 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.0 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.4 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.8 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.1 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 1.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 1.3 GO:0007631 feeding behavior(GO:0007631)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.3 GO:0019815 B cell receptor complex(GO:0019815)
1.3 3.8 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
1.0 14.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.6 4.8 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.6 6.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 8.4 GO:0036449 microtubule minus-end(GO:0036449)
0.5 4.7 GO:0070552 BRISC complex(GO:0070552)
0.4 3.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.4 3.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 2.4 GO:0042825 TAP complex(GO:0042825)
0.3 1.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.3 1.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 2.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 5.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 3.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.8 GO:0060091 kinocilium(GO:0060091)
0.2 1.4 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 6.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 2.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.2 1.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 2.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 2.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 10.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.1 GO:0070876 SOSS complex(GO:0070876)
0.1 9.4 GO:0008180 COP9 signalosome(GO:0008180)
0.1 8.7 GO:0097542 ciliary tip(GO:0097542)
0.1 1.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 2.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 12.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.4 GO:0097342 ripoptosome(GO:0097342)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 25.4 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 0.8 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0016938 kinesin I complex(GO:0016938)
0.1 5.5 GO:1990391 DNA repair complex(GO:1990391)
0.1 7.6 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 3.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.2 GO:0005861 troponin complex(GO:0005861)
0.1 0.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 4.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.8 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 4.9 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 18.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 2.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.9 GO:0071437 invadopodium(GO:0071437)
0.0 4.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 2.2 GO:0002102 podosome(GO:0002102)
0.0 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.0 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 2.9 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 13.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 2.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.6 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 5.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 11.3 GO:0005925 focal adhesion(GO:0005925)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.3 5.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.0 6.7 GO:0046979 TAP2 binding(GO:0046979)
0.8 2.5 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.8 15.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.8 3.8 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.7 3.0 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.7 3.7 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.7 3.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 3.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.5 4.8 GO:1990763 arrestin family protein binding(GO:1990763)
0.5 1.0 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.5 3.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.5 6.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 4.7 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.5 7.4 GO:0045159 myosin II binding(GO:0045159)
0.5 24.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 5.8 GO:0051525 NFAT protein binding(GO:0051525)
0.4 3.5 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 3.0 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 4.7 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.4 7.7 GO:0004568 chitinase activity(GO:0004568)
0.4 1.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.4 4.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 1.6 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.4 5.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 2.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 4.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 3.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 5.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 1.6 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 7.1 GO:0043495 protein anchor(GO:0043495)
0.2 11.1 GO:0005109 frizzled binding(GO:0005109)
0.2 1.4 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 0.8 GO:0045322 unmethylated CpG binding(GO:0045322)
0.2 3.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 10.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 1.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 0.6 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 3.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 1.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.2 3.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.6 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.2 1.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 2.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 3.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 3.2 GO:0043422 protein kinase B binding(GO:0043422)
0.1 3.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 3.0 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 10.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 8.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 4.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.3 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 4.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 4.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 1.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 1.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.8 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 18.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.2 GO:0031014 troponin T binding(GO:0031014)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 4.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 11.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.0 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.1 GO:0048156 tau protein binding(GO:0048156)
0.1 1.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 3.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 3.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 5.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 1.8 GO:0030275 LRR domain binding(GO:0030275)
0.1 2.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 2.1 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 1.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 4.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 2.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 22.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.8 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 3.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 6.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0003924 GTPase activity(GO:0003924)
0.0 6.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 4.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 2.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 2.1 GO:0016798 hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.0 0.0 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 17.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.4 5.9 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 23.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 7.7 PID IL5 PATHWAY IL5-mediated signaling events
0.3 18.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 11.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 2.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 4.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 17.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2 7.9 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 6.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 12.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 6.3 PID IL23 PATHWAY IL23-mediated signaling events
0.1 7.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 7.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 4.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 2.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 1.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 2.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 11.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 3.0 ST GA12 PATHWAY G alpha 12 Pathway
0.1 4.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 2.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 2.8 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.8 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.8 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.4 PID P73PATHWAY p73 transcription factor network
0.0 3.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 2.1 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 1.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.7 6.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 15.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 28.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.3 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.2 11.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 5.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 5.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 4.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 1.4 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.2 12.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 5.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 2.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 4.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.2 4.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 4.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.8 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 5.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 4.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.8 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 1.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 3.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 4.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 4.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 12.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 8.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 3.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 3.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 7.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 8.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 21.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 3.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 4.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.3 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.5 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.6 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)