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Illumina Body Map 2: averaged replicates
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Results for NFKB1
Z-value: 2.52
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Transcription factors associated with NFKB1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NFKB1
|
ENSG00000109320.7 | nuclear factor kappa B subunit 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFKB1 | hg19_v2_chr4_+_103422499_103422632 | 0.65 | 5.0e-05 | Click! |
Activity profile of NFKB1 motif
Sorted Z-values of NFKB1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_219745020 | 8.10 |
ENST00000258411.3
|
WNT10A
|
wingless-type MMTV integration site family, member 10A |
| chr6_-_31550192 | 6.62 |
ENST00000429299.2
ENST00000446745.2 |
LTB
|
lymphotoxin beta (TNF superfamily, member 3) |
| chr19_+_42381173 | 6.56 |
ENST00000221972.3
|
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr6_+_31540056 | 6.10 |
ENST00000418386.2
|
LTA
|
lymphotoxin alpha |
| chr19_+_17638059 | 5.82 |
ENST00000599164.1
ENST00000449408.2 ENST00000600871.1 ENST00000599124.1 |
FAM129C
|
family with sequence similarity 129, member C |
| chr19_+_42381337 | 5.77 |
ENST00000597454.1
ENST00000444740.2 |
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr22_-_37640277 | 5.66 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr1_-_202130702 | 5.47 |
ENST00000309017.3
ENST00000477554.1 ENST00000492451.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr22_-_37640456 | 5.40 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr16_+_50730910 | 5.30 |
ENST00000300589.2
|
NOD2
|
nucleotide-binding oligomerization domain containing 2 |
| chr5_+_35852797 | 5.25 |
ENST00000508941.1
|
IL7R
|
interleukin 7 receptor |
| chr17_-_61776522 | 5.17 |
ENST00000582055.1
|
LIMD2
|
LIM domain containing 2 |
| chr19_+_17638041 | 5.12 |
ENST00000601861.1
|
FAM129C
|
family with sequence similarity 129, member C |
| chr12_-_55375622 | 4.96 |
ENST00000316577.8
|
TESPA1
|
thymocyte expressed, positive selection associated 1 |
| chr14_+_22573582 | 4.47 |
ENST00000390453.1
|
TRAV24
|
T cell receptor alpha variable 24 |
| chr9_-_139927462 | 4.39 |
ENST00000314412.6
|
FUT7
|
fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| chr12_-_58131931 | 4.39 |
ENST00000547588.1
|
AGAP2
|
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| chr17_-_61777090 | 4.28 |
ENST00000578061.1
|
LIMD2
|
LIM domain containing 2 |
| chr19_+_1067271 | 4.19 |
ENST00000536472.1
ENST00000590214.1 |
HMHA1
|
histocompatibility (minor) HA-1 |
| chr4_-_74864386 | 4.05 |
ENST00000296027.4
|
CXCL5
|
chemokine (C-X-C motif) ligand 5 |
| chr12_-_9913489 | 4.01 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr3_-_111852061 | 4.00 |
ENST00000488580.1
ENST00000460387.2 ENST00000484193.1 ENST00000487901.1 |
GCSAM
|
germinal center-associated, signaling and motility |
| chr11_+_128562372 | 3.94 |
ENST00000344954.6
|
FLI1
|
Fli-1 proto-oncogene, ETS transcription factor |
| chr11_+_102188224 | 3.90 |
ENST00000263464.3
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr19_+_1067144 | 3.90 |
ENST00000313093.2
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr4_+_74735102 | 3.89 |
ENST00000395761.3
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| chr7_+_143013198 | 3.81 |
ENST00000343257.2
|
CLCN1
|
chloride channel, voltage-sensitive 1 |
| chr22_+_37318082 | 3.76 |
ENST00000406230.1
|
CSF2RB
|
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| chr19_+_1067492 | 3.71 |
ENST00000586866.1
|
HMHA1
|
histocompatibility (minor) HA-1 |
| chr1_-_186649543 | 3.70 |
ENST00000367468.5
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| chr1_-_202129105 | 3.69 |
ENST00000367279.4
|
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr19_+_45504688 | 3.61 |
ENST00000221452.8
ENST00000540120.1 ENST00000505236.1 |
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B |
| chr6_+_106534192 | 3.52 |
ENST00000369091.2
ENST00000369096.4 |
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr5_-_149792295 | 3.50 |
ENST00000518797.1
ENST00000524315.1 ENST00000009530.7 ENST00000377795.3 |
CD74
|
CD74 molecule, major histocompatibility complex, class II invariant chain |
| chr14_+_75988851 | 3.44 |
ENST00000555504.1
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr16_+_3096638 | 3.43 |
ENST00000336577.4
|
MMP25
|
matrix metallopeptidase 25 |
| chr3_-_111852128 | 3.38 |
ENST00000308910.4
|
GCSAM
|
germinal center-associated, signaling and motility |
| chr4_-_185395191 | 3.28 |
ENST00000510814.1
ENST00000507523.1 ENST00000506230.1 |
IRF2
|
interferon regulatory factor 2 |
| chr11_+_102188272 | 3.27 |
ENST00000532808.1
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr9_+_82188077 | 3.24 |
ENST00000425506.1
|
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr20_-_50159198 | 3.24 |
ENST00000371564.3
ENST00000396009.3 ENST00000610033.1 |
NFATC2
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 |
| chr19_-_54784353 | 3.23 |
ENST00000391746.1
|
LILRB2
|
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| chr14_+_52313833 | 3.17 |
ENST00000553560.1
|
GNG2
|
guanine nucleotide binding protein (G protein), gamma 2 |
| chr9_-_136344197 | 3.17 |
ENST00000414172.1
ENST00000371897.4 |
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6 |
| chr19_+_50922187 | 3.09 |
ENST00000595883.1
ENST00000597855.1 ENST00000596074.1 ENST00000439922.2 ENST00000594685.1 ENST00000270632.7 |
SPIB
|
Spi-B transcription factor (Spi-1/PU.1 related) |
| chr1_+_111770278 | 3.09 |
ENST00000369748.4
|
CHI3L2
|
chitinase 3-like 2 |
| chr1_-_202129704 | 3.08 |
ENST00000476061.1
ENST00000544762.1 ENST00000467283.1 ENST00000464870.1 ENST00000435759.2 ENST00000486116.1 ENST00000543735.1 ENST00000308986.5 ENST00000477625.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr22_+_27053422 | 3.08 |
ENST00000413665.1
ENST00000421151.1 ENST00000456129.1 ENST00000430080.1 |
MIAT
|
myocardial infarction associated transcript (non-protein coding) |
| chr5_+_82767284 | 3.07 |
ENST00000265077.3
|
VCAN
|
versican |
| chr19_-_6591113 | 3.05 |
ENST00000423145.3
ENST00000245903.3 |
CD70
|
CD70 molecule |
| chr14_-_70655684 | 3.03 |
ENST00000356921.2
ENST00000381269.2 ENST00000357887.3 |
SLC8A3
|
solute carrier family 8 (sodium/calcium exchanger), member 3 |
| chr12_-_57023995 | 3.02 |
ENST00000549884.1
ENST00000546695.1 |
BAZ2A
|
bromodomain adjacent to zinc finger domain, 2A |
| chr7_+_120969045 | 2.99 |
ENST00000222462.2
|
WNT16
|
wingless-type MMTV integration site family, member 16 |
| chr16_+_50775971 | 2.96 |
ENST00000311559.9
ENST00000564326.1 ENST00000566206.1 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr9_+_82187487 | 2.96 |
ENST00000435650.1
ENST00000414465.1 ENST00000376537.4 ENST00000376534.4 |
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr14_-_51297837 | 2.94 |
ENST00000245441.5
ENST00000389868.3 ENST00000382041.3 ENST00000324330.9 ENST00000453196.1 ENST00000453401.2 |
NIN
|
ninein (GSK3B interacting protein) |
| chr16_+_50776021 | 2.91 |
ENST00000566679.2
ENST00000564634.1 ENST00000398568.2 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr6_+_32605134 | 2.91 |
ENST00000343139.5
ENST00000395363.1 ENST00000496318.1 |
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr10_+_104154229 | 2.86 |
ENST00000428099.1
ENST00000369966.3 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr19_-_17958771 | 2.85 |
ENST00000534444.1
|
JAK3
|
Janus kinase 3 |
| chr14_+_61789382 | 2.83 |
ENST00000555082.1
|
PRKCH
|
protein kinase C, eta |
| chr22_+_27053567 | 2.83 |
ENST00000449717.1
ENST00000453023.1 |
MIAT
|
myocardial infarction associated transcript (non-protein coding) |
| chr16_+_50775948 | 2.81 |
ENST00000569681.1
ENST00000569418.1 ENST00000540145.1 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr14_-_51297360 | 2.80 |
ENST00000496749.1
|
NIN
|
ninein (GSK3B interacting protein) |
| chr22_+_27053190 | 2.77 |
ENST00000439738.1
ENST00000422403.1 ENST00000436238.1 ENST00000425476.1 ENST00000455640.1 ENST00000451141.1 ENST00000452429.1 ENST00000423278.1 |
MIAT
|
myocardial infarction associated transcript (non-protein coding) |
| chrX_-_30595959 | 2.73 |
ENST00000378962.3
|
CXorf21
|
chromosome X open reading frame 21 |
| chr9_+_82187630 | 2.73 |
ENST00000265284.6
|
TLE4
|
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) |
| chr6_+_138188351 | 2.68 |
ENST00000421450.1
|
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr10_+_99609996 | 2.61 |
ENST00000370602.1
|
GOLGA7B
|
golgin A7 family, member B |
| chr2_+_74212073 | 2.60 |
ENST00000441217.1
|
AC073046.25
|
AC073046.25 |
| chr22_-_39151434 | 2.54 |
ENST00000439339.1
|
SUN2
|
Sad1 and UNC84 domain containing 2 |
| chr19_+_496454 | 2.53 |
ENST00000346144.4
ENST00000215637.3 ENST00000382683.4 |
MADCAM1
|
mucosal vascular addressin cell adhesion molecule 1 |
| chr14_-_51297197 | 2.50 |
ENST00000382043.4
|
NIN
|
ninein (GSK3B interacting protein) |
| chr14_+_75988768 | 2.49 |
ENST00000286639.6
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr14_-_103589246 | 2.49 |
ENST00000558224.1
ENST00000560742.1 |
LINC00677
|
long intergenic non-protein coding RNA 677 |
| chr1_+_156123318 | 2.47 |
ENST00000368285.3
|
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| chr1_+_111770294 | 2.47 |
ENST00000474304.2
|
CHI3L2
|
chitinase 3-like 2 |
| chr1_+_156123359 | 2.44 |
ENST00000368284.1
ENST00000368286.2 ENST00000438830.1 |
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| chr6_-_32821599 | 2.42 |
ENST00000354258.4
|
TAP1
|
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| chr15_-_89438742 | 2.42 |
ENST00000562281.1
ENST00000562889.1 ENST00000359595.3 |
HAPLN3
|
hyaluronan and proteoglycan link protein 3 |
| chr4_-_76944621 | 2.42 |
ENST00000306602.1
|
CXCL10
|
chemokine (C-X-C motif) ligand 10 |
| chr2_+_61108771 | 2.41 |
ENST00000394479.3
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr19_-_47734448 | 2.37 |
ENST00000439096.2
|
BBC3
|
BCL2 binding component 3 |
| chr11_+_118754475 | 2.34 |
ENST00000292174.4
|
CXCR5
|
chemokine (C-X-C motif) receptor 5 |
| chr13_+_108922228 | 2.34 |
ENST00000542136.1
|
TNFSF13B
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr1_-_236030216 | 2.32 |
ENST00000389794.3
ENST00000389793.2 |
LYST
|
lysosomal trafficking regulator |
| chr6_+_32605195 | 2.30 |
ENST00000374949.2
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr19_-_17958832 | 2.28 |
ENST00000458235.1
|
JAK3
|
Janus kinase 3 |
| chr11_-_75062730 | 2.20 |
ENST00000420843.2
ENST00000360025.3 |
ARRB1
|
arrestin, beta 1 |
| chr13_+_108921977 | 2.19 |
ENST00000430559.1
ENST00000375887.4 |
TNFSF13B
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr6_+_29691198 | 2.16 |
ENST00000440587.2
ENST00000434407.2 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr6_+_29691056 | 2.14 |
ENST00000414333.1
ENST00000334668.4 ENST00000259951.7 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr1_+_111770232 | 2.14 |
ENST00000369744.2
|
CHI3L2
|
chitinase 3-like 2 |
| chr11_-_77185094 | 2.14 |
ENST00000278568.4
ENST00000356341.3 |
PAK1
|
p21 protein (Cdc42/Rac)-activated kinase 1 |
| chr4_-_185395672 | 2.14 |
ENST00000393593.3
|
IRF2
|
interferon regulatory factor 2 |
| chr6_+_138188378 | 2.12 |
ENST00000420009.1
|
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr17_+_40440481 | 2.12 |
ENST00000590726.2
ENST00000452307.2 ENST00000444283.1 ENST00000588868.1 |
STAT5A
|
signal transducer and activator of transcription 5A |
| chr1_-_8000872 | 2.12 |
ENST00000377507.3
|
TNFRSF9
|
tumor necrosis factor receptor superfamily, member 9 |
| chr1_-_206671061 | 2.07 |
ENST00000367119.1
|
C1orf147
|
chromosome 1 open reading frame 147 |
| chr11_-_46142505 | 2.05 |
ENST00000524497.1
ENST00000418153.2 |
PHF21A
|
PHD finger protein 21A |
| chr15_+_85923797 | 2.05 |
ENST00000559362.1
|
AKAP13
|
A kinase (PRKA) anchor protein 13 |
| chrX_-_21676442 | 2.02 |
ENST00000379499.2
|
KLHL34
|
kelch-like family member 34 |
| chr2_-_191885686 | 2.01 |
ENST00000432058.1
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa |
| chr1_+_37940153 | 1.99 |
ENST00000373087.6
|
ZC3H12A
|
zinc finger CCCH-type containing 12A |
| chr14_+_96342729 | 1.99 |
ENST00000504119.1
|
LINC00617
|
long intergenic non-protein coding RNA 617 |
| chr1_+_100818009 | 1.98 |
ENST00000370125.2
ENST00000361544.6 ENST00000370124.3 |
CDC14A
|
cell division cycle 14A |
| chr1_+_89990378 | 1.98 |
ENST00000449440.1
|
LRRC8B
|
leucine rich repeat containing 8 family, member B |
| chr19_+_42364460 | 1.96 |
ENST00000593863.1
|
RPS19
|
ribosomal protein S19 |
| chr6_+_138188551 | 1.94 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr7_-_102252589 | 1.90 |
ENST00000520042.1
|
RASA4
|
RAS p21 protein activator 4 |
| chr20_-_60294804 | 1.89 |
ENST00000317652.1
|
RP11-429E11.3
|
Uncharacterized protein |
| chr4_-_122148620 | 1.89 |
ENST00000509841.1
|
TNIP3
|
TNFAIP3 interacting protein 3 |
| chr1_-_155959853 | 1.87 |
ENST00000462460.2
ENST00000368316.1 |
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| chr22_-_39151995 | 1.86 |
ENST00000405018.1
ENST00000438058.1 |
SUN2
|
Sad1 and UNC84 domain containing 2 |
| chr11_-_3862206 | 1.86 |
ENST00000351018.4
|
RHOG
|
ras homolog family member G |
| chr19_+_35485682 | 1.85 |
ENST00000599564.1
|
GRAMD1A
|
GRAM domain containing 1A |
| chr19_-_51920873 | 1.85 |
ENST00000441969.3
ENST00000525998.1 ENST00000436984.2 |
SIGLEC10
|
sialic acid binding Ig-like lectin 10 |
| chr11_-_46142948 | 1.84 |
ENST00000257821.4
|
PHF21A
|
PHD finger protein 21A |
| chr15_+_85923856 | 1.82 |
ENST00000560302.1
ENST00000394518.2 ENST00000361243.2 ENST00000560256.1 |
AKAP13
|
A kinase (PRKA) anchor protein 13 |
| chr17_-_7108436 | 1.81 |
ENST00000493294.1
|
DLG4
|
discs, large homolog 4 (Drosophila) |
| chr12_-_25403737 | 1.81 |
ENST00000256078.4
ENST00000556131.1 ENST00000311936.3 ENST00000557334.1 |
KRAS
|
Kirsten rat sarcoma viral oncogene homolog |
| chr11_-_75062829 | 1.80 |
ENST00000393505.4
|
ARRB1
|
arrestin, beta 1 |
| chr2_+_208394616 | 1.80 |
ENST00000432329.2
ENST00000353267.3 ENST00000445803.1 |
CREB1
|
cAMP responsive element binding protein 1 |
| chr17_+_40440094 | 1.79 |
ENST00000546010.2
|
STAT5A
|
signal transducer and activator of transcription 5A |
| chr17_-_4852332 | 1.78 |
ENST00000572383.1
|
PFN1
|
profilin 1 |
| chr3_+_52280173 | 1.76 |
ENST00000296487.4
|
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr1_+_28285973 | 1.76 |
ENST00000373884.5
|
XKR8
|
XK, Kell blood group complex subunit-related family, member 8 |
| chr12_+_56732658 | 1.76 |
ENST00000228534.4
|
IL23A
|
interleukin 23, alpha subunit p19 |
| chr6_+_32821924 | 1.74 |
ENST00000374859.2
ENST00000453265.2 |
PSMB9
|
proteasome (prosome, macropain) subunit, beta type, 9 |
| chr1_+_26872324 | 1.74 |
ENST00000531382.1
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chr19_-_40324255 | 1.71 |
ENST00000593685.1
ENST00000600611.1 |
DYRK1B
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| chr22_-_39151947 | 1.71 |
ENST00000216064.4
|
SUN2
|
Sad1 and UNC84 domain containing 2 |
| chr1_+_100818156 | 1.70 |
ENST00000336454.3
|
CDC14A
|
cell division cycle 14A |
| chr9_+_134103496 | 1.70 |
ENST00000498010.1
ENST00000476004.1 ENST00000528406.1 |
NUP214
|
nucleoporin 214kDa |
| chr11_-_47400062 | 1.70 |
ENST00000533030.1
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr14_+_96343100 | 1.68 |
ENST00000503525.2
|
LINC00617
|
long intergenic non-protein coding RNA 617 |
| chr20_+_57430162 | 1.68 |
ENST00000450130.1
ENST00000349036.3 ENST00000423897.1 |
GNAS
|
GNAS complex locus |
| chr19_-_51920952 | 1.67 |
ENST00000356298.5
ENST00000339313.5 ENST00000529627.1 ENST00000439889.2 ENST00000353836.5 ENST00000432469.2 |
SIGLEC10
|
sialic acid binding Ig-like lectin 10 |
| chr6_-_44233361 | 1.66 |
ENST00000275015.5
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| chr2_+_163175394 | 1.66 |
ENST00000446271.1
ENST00000429691.2 |
GCA
|
grancalcin, EF-hand calcium binding protein |
| chr19_+_35940486 | 1.66 |
ENST00000246549.2
|
FFAR2
|
free fatty acid receptor 2 |
| chr2_+_208394455 | 1.62 |
ENST00000430624.1
|
CREB1
|
cAMP responsive element binding protein 1 |
| chr3_+_52280220 | 1.61 |
ENST00000409502.3
ENST00000323588.4 |
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr19_+_51728316 | 1.60 |
ENST00000436584.2
ENST00000421133.2 ENST00000391796.3 ENST00000262262.4 |
CD33
|
CD33 molecule |
| chr10_-_73533255 | 1.59 |
ENST00000394957.3
|
C10orf54
|
chromosome 10 open reading frame 54 |
| chr11_-_46142615 | 1.58 |
ENST00000529734.1
ENST00000323180.6 |
PHF21A
|
PHD finger protein 21A |
| chr16_+_85936295 | 1.58 |
ENST00000563180.1
ENST00000564617.1 ENST00000564803.1 |
IRF8
|
interferon regulatory factor 8 |
| chrX_+_109245863 | 1.57 |
ENST00000372072.3
|
TMEM164
|
transmembrane protein 164 |
| chr19_-_51920835 | 1.56 |
ENST00000442846.3
ENST00000530476.1 |
SIGLEC10
|
sialic acid binding Ig-like lectin 10 |
| chr11_-_47399942 | 1.54 |
ENST00000227163.4
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr17_+_7590734 | 1.53 |
ENST00000457584.2
|
WRAP53
|
WD repeat containing, antisense to TP53 |
| chr4_+_103422499 | 1.52 |
ENST00000511926.1
ENST00000507079.1 |
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| chr3_-_156878482 | 1.51 |
ENST00000295925.4
|
CCNL1
|
cyclin L1 |
| chr18_-_28742813 | 1.51 |
ENST00000257197.3
ENST00000257198.5 |
DSC1
|
desmocollin 1 |
| chr2_+_61108650 | 1.50 |
ENST00000295025.8
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr14_-_35873856 | 1.50 |
ENST00000553342.1
ENST00000216797.5 ENST00000557140.1 |
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| chr3_+_52279737 | 1.49 |
ENST00000457351.2
|
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr7_+_69064300 | 1.49 |
ENST00000342771.4
|
AUTS2
|
autism susceptibility candidate 2 |
| chr6_+_14117872 | 1.48 |
ENST00000379153.3
|
CD83
|
CD83 molecule |
| chr8_-_130951940 | 1.47 |
ENST00000522250.1
ENST00000522941.1 ENST00000522746.1 ENST00000520204.1 ENST00000519070.1 ENST00000520254.1 ENST00000519824.2 ENST00000519540.1 |
FAM49B
|
family with sequence similarity 49, member B |
| chr1_+_89990431 | 1.47 |
ENST00000330947.2
ENST00000358200.4 |
LRRC8B
|
leucine rich repeat containing 8 family, member B |
| chr11_+_72525353 | 1.47 |
ENST00000321297.5
ENST00000534905.1 ENST00000540567.1 |
ATG16L2
|
autophagy related 16-like 2 (S. cerevisiae) |
| chr6_+_33378517 | 1.45 |
ENST00000428274.1
|
PHF1
|
PHD finger protein 1 |
| chr5_+_159895275 | 1.44 |
ENST00000517927.1
|
MIR146A
|
microRNA 146a |
| chr6_+_29910301 | 1.44 |
ENST00000376809.5
ENST00000376802.2 |
HLA-A
|
major histocompatibility complex, class I, A |
| chr22_+_27053545 | 1.43 |
ENST00000458302.1
ENST00000419237.1 |
MIAT
|
myocardial infarction associated transcript (non-protein coding) |
| chr11_-_47400078 | 1.42 |
ENST00000378538.3
|
SPI1
|
spleen focus forming virus (SFFV) proviral integration oncogene |
| chr6_-_111804905 | 1.41 |
ENST00000358835.3
ENST00000435970.1 |
REV3L
|
REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| chr20_+_9494987 | 1.41 |
ENST00000427562.2
ENST00000246070.2 |
LAMP5
|
lysosomal-associated membrane protein family, member 5 |
| chr3_+_52279902 | 1.40 |
ENST00000457454.1
|
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr1_-_155658085 | 1.40 |
ENST00000311573.5
ENST00000438245.2 |
YY1AP1
|
YY1 associated protein 1 |
| chr2_-_240230890 | 1.39 |
ENST00000446876.1
|
HDAC4
|
histone deacetylase 4 |
| chr21_+_34775772 | 1.39 |
ENST00000405436.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr19_-_4831701 | 1.38 |
ENST00000248244.5
|
TICAM1
|
toll-like receptor adaptor molecule 1 |
| chr6_+_18155632 | 1.38 |
ENST00000297792.5
|
KDM1B
|
lysine (K)-specific demethylase 1B |
| chr9_-_125667494 | 1.38 |
ENST00000335387.5
ENST00000357244.2 ENST00000373665.2 |
RC3H2
|
ring finger and CCCH-type domains 2 |
| chr17_+_46189311 | 1.37 |
ENST00000582481.1
|
SNX11
|
sorting nexin 11 |
| chr6_+_144471643 | 1.36 |
ENST00000367568.4
|
STX11
|
syntaxin 11 |
| chr14_+_64970427 | 1.35 |
ENST00000553583.1
|
ZBTB1
|
zinc finger and BTB domain containing 1 |
| chr12_-_54813229 | 1.33 |
ENST00000293379.4
|
ITGA5
|
integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| chr21_+_34775698 | 1.32 |
ENST00000381995.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr19_+_42364313 | 1.31 |
ENST00000601492.1
ENST00000600467.1 ENST00000221975.2 |
RPS19
|
ribosomal protein S19 |
| chr11_-_72853267 | 1.31 |
ENST00000409418.4
|
FCHSD2
|
FCH and double SH3 domains 2 |
| chr1_+_10093188 | 1.31 |
ENST00000377153.1
|
UBE4B
|
ubiquitination factor E4B |
| chr3_+_57261859 | 1.31 |
ENST00000495803.1
ENST00000444459.1 |
APPL1
|
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| chr10_+_12391685 | 1.31 |
ENST00000378845.1
|
CAMK1D
|
calcium/calmodulin-dependent protein kinase ID |
| chr10_+_30723045 | 1.30 |
ENST00000542547.1
ENST00000415139.1 |
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr17_+_38465441 | 1.30 |
ENST00000577646.1
ENST00000254066.5 |
RARA
|
retinoic acid receptor, alpha |
| chr10_+_12391481 | 1.29 |
ENST00000378847.3
|
CAMK1D
|
calcium/calmodulin-dependent protein kinase ID |
| chr4_-_140098339 | 1.27 |
ENST00000394235.2
|
ELF2
|
E74-like factor 2 (ets domain transcription factor) |
| chr4_+_142557717 | 1.26 |
ENST00000320650.4
ENST00000296545.7 |
IL15
|
interleukin 15 |
| chr16_+_6069072 | 1.25 |
ENST00000547605.1
ENST00000550418.1 ENST00000553186.1 |
RBFOX1
|
RNA binding protein, fox-1 homolog (C. elegans) 1 |
| chr3_+_101546827 | 1.25 |
ENST00000461724.1
ENST00000483180.1 ENST00000394054.2 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr12_-_12849073 | 1.25 |
ENST00000332427.2
ENST00000540796.1 |
GPR19
|
G protein-coupled receptor 19 |
| chr5_-_150466692 | 1.25 |
ENST00000315050.7
ENST00000523338.1 ENST00000522100.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr10_-_6104253 | 1.23 |
ENST00000256876.6
ENST00000379954.1 ENST00000379959.3 |
IL2RA
|
interleukin 2 receptor, alpha |
| chr2_+_112895939 | 1.23 |
ENST00000331203.2
ENST00000409903.1 ENST00000409667.3 ENST00000409450.3 |
FBLN7
|
fibulin 7 |
| chr9_-_125667618 | 1.23 |
ENST00000423239.2
|
RC3H2
|
ring finger and CCCH-type domains 2 |
| chr17_-_7154984 | 1.22 |
ENST00000574322.1
|
CTDNEP1
|
CTD nuclear envelope phosphatase 1 |
| chr14_+_103243813 | 1.22 |
ENST00000560371.1
ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1 |
TRAF3
|
TNF receptor-associated factor 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of NFKB1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.7 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 2.7 | 8.2 | GO:0090222 | centrosome-templated microtubule nucleation(GO:0090222) |
| 2.2 | 6.7 | GO:0072573 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
| 2.0 | 6.1 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 1.7 | 5.1 | GO:0045210 | negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210) |
| 1.5 | 4.4 | GO:0002522 | leukocyte migration involved in immune response(GO:0002522) |
| 1.3 | 5.3 | GO:1902523 | detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 1.2 | 3.7 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 1.2 | 3.5 | GO:1990654 | sebum secreting cell proliferation(GO:1990654) |
| 1.2 | 3.5 | GO:0002906 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) |
| 1.2 | 5.8 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 1.1 | 3.4 | GO:0045062 | extrathymic T cell selection(GO:0045062) |
| 1.1 | 2.1 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183) |
| 1.0 | 4.2 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 1.0 | 11.1 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 1.0 | 3.8 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 0.9 | 7.4 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.9 | 4.5 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296) |
| 0.8 | 2.3 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.8 | 3.8 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.8 | 16.8 | GO:0048535 | lymph node development(GO:0048535) |
| 0.8 | 3.8 | GO:0038156 | interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.7 | 7.2 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 0.7 | 5.0 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.7 | 4.8 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.7 | 6.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.7 | 3.3 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.7 | 2.0 | GO:2000627 | regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) |
| 0.7 | 6.5 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.6 | 3.9 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.6 | 2.5 | GO:2000174 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.6 | 2.4 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.6 | 1.8 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.6 | 1.8 | GO:0045083 | negative regulation of interleukin-12 biosynthetic process(GO:0045083) |
| 0.6 | 3.9 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.6 | 1.7 | GO:0002232 | leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.6 | 2.2 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.5 | 8.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.5 | 1.5 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.5 | 2.0 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.5 | 1.5 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 0.5 | 4.7 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.5 | 2.7 | GO:2001153 | regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153) |
| 0.4 | 7.7 | GO:0006032 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.4 | 7.5 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.4 | 3.2 | GO:0002774 | Fc receptor mediated inhibitory signaling pathway(GO:0002774) |
| 0.4 | 3.1 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.4 | 2.6 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.4 | 8.9 | GO:0072540 | T-helper 17 cell lineage commitment(GO:0072540) |
| 0.3 | 3.4 | GO:0034350 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.3 | 3.0 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.3 | 4.0 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.3 | 1.6 | GO:0001828 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.3 | 1.2 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.3 | 3.7 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 0.3 | 0.8 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 0.3 | 3.4 | GO:0060022 | hard palate development(GO:0060022) |
| 0.3 | 1.3 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.2 | 1.5 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.2 | 2.1 | GO:0061052 | negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) |
| 0.2 | 1.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 1.6 | GO:0008626 | granzyme-mediated apoptotic signaling pathway(GO:0008626) |
| 0.2 | 4.4 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.2 | 3.0 | GO:0097688 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.2 | 2.5 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.2 | 2.2 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.2 | 2.6 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.2 | 1.5 | GO:2000567 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 0.2 | 2.7 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.2 | 2.1 | GO:1904327 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.2 | 0.2 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.2 | 1.4 | GO:0045350 | interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.2 | 3.1 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.8 | GO:0043652 | engulfment of apoptotic cell(GO:0043652) |
| 0.2 | 0.8 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.2 | 1.4 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.2 | 5.7 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.2 | 1.7 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
| 0.2 | 0.9 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.2 | 1.6 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.2 | 1.2 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.2 | 0.3 | GO:1990619 | histone H3-K9 deacetylation(GO:1990619) |
| 0.2 | 1.5 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.2 | 1.1 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.2 | 0.6 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.2 | 0.8 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.2 | 3.0 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.2 | 0.5 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.1 | 1.2 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 3.3 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.1 | 3.2 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 3.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 3.4 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) |
| 0.1 | 0.8 | GO:2001038 | regulation of cellular response to drug(GO:2001038) |
| 0.1 | 8.9 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.1 | 1.7 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.5 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.1 | 2.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 1.7 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.1 | 14.1 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.1 | 3.9 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.1 | 1.4 | GO:0034720 | histone H3-K4 demethylation(GO:0034720) |
| 0.1 | 0.8 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 0.1 | 0.3 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 0.1 | 1.6 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.1 | 0.9 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 1.3 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.1 | 2.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.1 | 3.6 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.8 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.1 | 0.2 | GO:0014858 | positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) |
| 0.1 | 0.4 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.1 | 1.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.6 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.1 | 2.5 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.1 | 1.0 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.1 | 3.1 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.1 | 13.2 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 0.5 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 3.2 | GO:0035428 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 0.2 | GO:0046832 | negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
| 0.1 | 8.6 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.1 | 0.5 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.1 | 0.7 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 1.9 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.1 | 1.2 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.1 | 1.4 | GO:0031629 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 3.2 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.1 | 0.3 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.1 | 0.3 | GO:0048840 | otolith development(GO:0048840) |
| 0.1 | 1.1 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 0.7 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 1.5 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.1 | 1.3 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 3.6 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.0 | 1.1 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 2.4 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 0.3 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.0 | 1.1 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 2.2 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 0.7 | GO:0035116 | embryonic hindlimb morphogenesis(GO:0035116) |
| 0.0 | 1.3 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.0 | 1.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.2 | GO:0044376 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.0 | 5.0 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.0 | 2.8 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 1.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.9 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 3.5 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 1.1 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.0 | 2.1 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.3 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.0 | 0.9 | GO:0032754 | positive regulation of interleukin-5 production(GO:0032754) |
| 0.0 | 2.1 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.0 | 1.1 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
| 0.0 | 1.8 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 1.9 | GO:0090003 | regulation of establishment of protein localization to plasma membrane(GO:0090003) |
| 0.0 | 6.1 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 1.4 | GO:0002756 | MyD88-independent toll-like receptor signaling pathway(GO:0002756) |
| 0.0 | 4.6 | GO:0042177 | negative regulation of protein catabolic process(GO:0042177) |
| 0.0 | 0.6 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 1.4 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 0.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 1.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.2 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.0 | 0.8 | GO:0030262 | apoptotic nuclear changes(GO:0030262) |
| 0.0 | 1.7 | GO:0071357 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 0.7 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.0 | 0.1 | GO:0060023 | soft palate development(GO:0060023) |
| 0.0 | 0.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.0 | 0.6 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 0.3 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.7 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.0 | 1.2 | GO:0001885 | endothelial cell development(GO:0001885) |
| 0.0 | 0.9 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.3 | GO:0050884 | neuromuscular process controlling posture(GO:0050884) |
| 0.0 | 1.0 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.0 | 0.2 | GO:0036481 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) |
| 0.0 | 2.5 | GO:0044070 | regulation of anion transport(GO:0044070) |
| 0.0 | 0.0 | GO:2000318 | positive regulation of T-helper 17 type immune response(GO:2000318) |
| 0.0 | 0.7 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 1.0 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.0 | 0.1 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.0 | 0.4 | GO:0030071 | regulation of mitotic metaphase/anaphase transition(GO:0030071) |
| 0.0 | 0.5 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.0 | 0.2 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 0.8 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.0 | 1.1 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.0 | 1.2 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.1 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
| 0.0 | 1.3 | GO:0007631 | feeding behavior(GO:0007631) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 12.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 1.3 | 3.8 | GO:0030526 | granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526) |
| 1.0 | 14.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.6 | 4.8 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.6 | 6.5 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.5 | 8.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.5 | 4.7 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.4 | 3.5 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.4 | 3.0 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 2.4 | GO:0042825 | TAP complex(GO:0042825) |
| 0.3 | 1.7 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.3 | 1.3 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.2 | 2.0 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.2 | 5.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 3.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 3.8 | GO:0060091 | kinocilium(GO:0060091) |
| 0.2 | 1.4 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.2 | 6.1 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.2 | 1.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.2 | 2.8 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.2 | 1.7 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.2 | 2.1 | GO:0072379 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.2 | 2.1 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 10.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 1.1 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 9.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 8.7 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 2.6 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.1 | 12.3 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 2.4 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 0.3 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.1 | 25.4 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.1 | 0.8 | GO:1990812 | growth cone filopodium(GO:1990812) |
| 0.1 | 0.7 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 0.4 | GO:0016938 | kinesin I complex(GO:0016938) |
| 0.1 | 5.5 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.1 | 7.6 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 1.8 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 2.5 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.3 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 3.3 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 1.2 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 0.3 | GO:0034753 | nuclear aryl hydrocarbon receptor complex(GO:0034753) |
| 0.1 | 4.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 0.8 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 4.9 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 1.4 | GO:0033202 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 18.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 1.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 1.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.2 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.0 | 2.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 0.9 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 4.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 2.2 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.0 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 1.0 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 2.9 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 13.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 0.2 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 2.4 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 2.4 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.3 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 2.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 1.5 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.5 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 5.0 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 2.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 1.4 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 2.3 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 11.3 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 2.3 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.5 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.2 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 0.8 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 1.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.2 | GO:0042405 | nuclear inclusion body(GO:0042405) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 4.0 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 1.3 | 5.2 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 1.0 | 6.7 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.8 | 2.5 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.8 | 15.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.8 | 3.8 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914) |
| 0.7 | 3.0 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.7 | 3.7 | GO:0050473 | prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.7 | 3.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.6 | 3.6 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.5 | 4.8 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.5 | 1.0 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.5 | 3.4 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.5 | 6.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.5 | 4.7 | GO:0004793 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.5 | 7.4 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.5 | 24.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.4 | 5.8 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.4 | 3.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.4 | 3.0 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.4 | 4.7 | GO:0023029 | MHC class Ib protein binding(GO:0023029) |
| 0.4 | 7.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.4 | 1.2 | GO:0019976 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 0.4 | 4.4 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.4 | 1.6 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) |
| 0.4 | 5.2 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.3 | 2.7 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.3 | 4.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 3.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.3 | 5.3 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.3 | 1.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.2 | 7.1 | GO:0043495 | protein anchor(GO:0043495) |
| 0.2 | 11.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 1.4 | GO:0036132 | 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522) |
| 0.2 | 0.8 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
| 0.2 | 3.2 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 10.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.2 | 1.4 | GO:0034648 | histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648) |
| 0.2 | 0.6 | GO:0004583 | dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) |
| 0.2 | 3.4 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.2 | 1.4 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.2 | 3.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 0.6 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.2 | 1.7 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.1 | 2.3 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.1 | 3.2 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.1 | 3.2 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 3.5 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 1.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 3.0 | GO:0001013 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 10.6 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 8.8 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 0.9 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 1.0 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 4.9 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 0.3 | GO:0032129 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 0.8 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 1.7 | GO:0051430 | corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 4.2 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.3 | GO:0016781 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.1 | 4.8 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.0 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 0.1 | 4.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.7 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 1.9 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.1 | 1.4 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.1 | 0.8 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 18.0 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.1 | 1.2 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 3.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.3 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.1 | 4.9 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 3.3 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.7 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.1 | 11.5 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.1 | 2.0 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.1 | 1.1 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 1.4 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.1 | 0.6 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.1 | 0.5 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.1 | 3.1 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 1.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 0.3 | GO:0004874 | aryl hydrocarbon receptor activity(GO:0004874) |
| 0.1 | 0.3 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.1 | 1.7 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.1 | 3.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 3.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.5 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 5.9 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 1.8 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.1 | 2.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 2.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 1.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 1.3 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 4.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.1 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.0 | 2.0 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 1.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 1.2 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.0 | 0.2 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.0 | 1.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 22.2 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.8 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.5 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.5 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 1.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.7 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.0 | 0.7 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.2 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.1 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.0 | 0.2 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 0.8 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 1.2 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.4 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 4.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 3.0 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 0.4 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.2 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 6.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.0 | 2.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.1 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.0 | 1.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.4 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 6.5 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.1 | GO:0070643 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.0 | 4.7 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.1 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.0 | 2.7 | GO:0004713 | protein tyrosine kinase activity(GO:0004713) |
| 0.0 | 2.1 | GO:0016798 | hydrolase activity, acting on glycosyl bonds(GO:0016798) |
| 0.0 | 0.0 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.0 | 1.2 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 17.5 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.4 | 5.9 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.4 | 23.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.3 | 7.7 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.3 | 18.2 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.2 | 11.9 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.2 | 2.0 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.2 | 4.9 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.2 | 17.1 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.2 | 7.9 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 6.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.2 | 12.3 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 6.3 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.1 | 7.5 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 2.1 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 7.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 4.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 4.5 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 2.0 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 1.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 3.3 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 2.1 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 2.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 1.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 11.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 1.6 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.1 | 3.0 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.1 | 4.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 2.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 2.8 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 2.8 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 1.8 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 1.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 1.7 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 0.6 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 2.2 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.0 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.0 | 1.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.5 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 1.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.5 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 1.2 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 2.9 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 1.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.9 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.9 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 2.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 3.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 2.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 1.2 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.7 | 6.5 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.5 | 15.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.4 | 28.8 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.3 | 1.0 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.2 | 11.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 5.6 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.2 | 5.2 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.2 | 4.6 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.2 | 1.4 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.2 | 12.3 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 5.0 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.2 | 2.1 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.2 | 4.8 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.2 | 4.0 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 4.9 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.8 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.1 | 5.2 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.1 | 4.0 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.8 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 1.9 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 3.4 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.1 | 3.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 4.4 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 4.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 12.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 3.2 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 8.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 4.3 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 1.0 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.1 | 3.0 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 3.1 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 0.7 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.1 | 7.7 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.1 | 8.8 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 21.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 3.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 1.1 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 4.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 1.4 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 4.9 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.7 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 1.9 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 1.3 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 1.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.5 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.0 | 3.1 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 1.9 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 1.2 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.8 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.8 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.6 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.9 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.4 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |