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Illumina Body Map 2: averaged replicates

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Results for NKX1-1

Z-value: 0.83

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Transcription factors associated with NKX1-1

Gene Symbol Gene ID Gene Info
ENSG00000235608.1 NK1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX1-1hg19_v2_chr4_-_1400119_1400119-0.841.3e-09Click!

Activity profile of NKX1-1 motif

Sorted Z-values of NKX1-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_16500599 3.11 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr12_+_16500571 3.09 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr12_+_16500037 2.98 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr3_+_186560476 1.32 ENST00000320741.2
ENST00000444204.2
adiponectin, C1Q and collagen domain containing
chr3_+_186560462 1.31 ENST00000412955.2
adiponectin, C1Q and collagen domain containing
chr10_+_5238793 0.89 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr14_+_22670455 0.83 ENST00000390460.1
T cell receptor alpha variable 26-2
chr9_+_34646651 0.81 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr7_+_26331541 0.80 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr17_-_27418537 0.75 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr12_+_64798826 0.69 ENST00000540203.1
exportin, tRNA
chr7_+_26331678 0.69 ENST00000446848.2
sorting nexin 10
chr9_+_34646624 0.67 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr10_+_120789223 0.66 ENST00000425699.1
nanos homolog 1 (Drosophila)
chr1_+_161691353 0.65 ENST00000367948.2
Fc receptor-like B
chr7_+_50348268 0.64 ENST00000438033.1
ENST00000439701.1
IKAROS family zinc finger 1 (Ikaros)
chr4_-_89442940 0.64 ENST00000527353.1
phosphatidylinositol glycan anchor biosynthesis, class Y
chrX_+_19362011 0.60 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
pyruvate dehydrogenase (lipoamide) alpha 1
chr13_-_36050819 0.59 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr2_-_47143160 0.58 ENST00000409800.1
ENST00000409218.1
multiple coagulation factor deficiency 2
chr1_-_21620877 0.55 ENST00000527991.1
endothelin converting enzyme 1
chr2_-_47142884 0.52 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
multiple coagulation factor deficiency 2
chr7_+_2559399 0.50 ENST00000222725.5
ENST00000359574.3
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_+_22730353 0.50 ENST00000390296.2
immunoglobulin lambda variable 5-45
chr6_-_167040693 0.48 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_82957433 0.47 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr19_-_14228541 0.47 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr22_-_39151463 0.46 ENST00000405510.1
ENST00000433561.1
Sad1 and UNC84 domain containing 2
chr22_+_41601209 0.46 ENST00000216237.5
l(3)mbt-like 2 (Drosophila)
chr2_+_8822113 0.46 ENST00000396290.1
ENST00000331129.3
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr5_+_66300464 0.46 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr10_+_99205894 0.45 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr3_+_158519654 0.44 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr10_-_99205607 0.44 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr17_+_57233087 0.43 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr10_+_99205959 0.41 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr1_-_221915418 0.41 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr14_-_24711764 0.39 ENST00000557921.1
ENST00000558476.1
TERF1 (TRF1)-interacting nuclear factor 2
chr11_-_124981475 0.38 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr9_+_116225999 0.37 ENST00000317613.6
regulator of G-protein signaling 3
chr7_-_6048650 0.37 ENST00000382321.4
ENST00000406569.3
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr11_-_47198380 0.37 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ADP-ribosylation factor GTPase activating protein 2
chr1_+_155278539 0.37 ENST00000447866.1
farnesyl diphosphate synthase
chrX_+_55026763 0.37 ENST00000374987.3
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
chr10_+_1095416 0.37 ENST00000358220.1
WD repeat domain 37
chr16_-_11036300 0.37 ENST00000331808.4
Dexi homolog (mouse)
chr1_+_62439037 0.36 ENST00000545929.1
InaD-like (Drosophila)
chr5_+_66300446 0.36 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr14_-_24711806 0.35 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_155278625 0.35 ENST00000368356.4
ENST00000356657.6
farnesyl diphosphate synthase
chr21_-_37914898 0.35 ENST00000399136.1
claudin 14
chr3_-_105587879 0.35 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr17_+_45286387 0.34 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr11_-_62521614 0.34 ENST00000527994.1
ENST00000394807.3
zinc finger and BTB domain containing 3
chr17_+_57232690 0.33 ENST00000262293.4
proline rich 11
chr11_-_65625678 0.32 ENST00000308162.5
cofilin 1 (non-muscle)
chr14_-_24711470 0.32 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chr15_-_78526942 0.32 ENST00000258873.4
acyl-CoA synthetase bubblegum family member 1
chr6_-_167040731 0.31 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_24711865 0.31 ENST00000399423.4
ENST00000267415.7
TERF1 (TRF1)-interacting nuclear factor 2
chr18_+_55888767 0.30 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_+_45286706 0.30 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr5_-_115890554 0.29 ENST00000509665.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr10_-_1094819 0.28 ENST00000429642.1
isopentenyl-diphosphate delta isomerase 1
chr12_+_28410128 0.28 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr4_-_54232144 0.28 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
sec1 family domain containing 2
chr17_-_8055747 0.28 ENST00000317276.4
ENST00000581703.1
period circadian clock 1
chr17_-_45266542 0.27 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
cell division cycle 27
chr2_+_105050794 0.26 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr15_+_96904487 0.26 ENST00000600790.1
Uncharacterized protein
chr10_-_1095050 0.25 ENST00000381344.3
isopentenyl-diphosphate delta isomerase 1
chr12_+_48499252 0.25 ENST00000549003.1
ENST00000550924.1
phosphofructokinase, muscle
chr19_+_50270219 0.25 ENST00000354293.5
ENST00000359032.5
adaptor-related protein complex 2, alpha 1 subunit
chr7_+_99647411 0.25 ENST00000438937.1
zinc finger and SCAN domain containing 21
chrX_-_153363125 0.25 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr7_-_6048702 0.24 ENST00000265849.7
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr18_+_63273310 0.23 ENST00000579862.1
RP11-775G23.1
chr11_-_62494821 0.23 ENST00000301785.5
heterogeneous nuclear ribonucleoprotein U-like 2
chr17_-_57232596 0.23 ENST00000581068.1
ENST00000330137.7
spindle and kinetochore associated complex subunit 2
chr14_+_32798462 0.22 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr7_-_33102338 0.22 ENST00000610140.1
5'-nucleotidase, cytosolic IIIA
chr7_-_33102399 0.21 ENST00000242210.7
5'-nucleotidase, cytosolic IIIA
chr11_-_59383617 0.21 ENST00000263847.1
oxysterol binding protein
chr12_-_102513843 0.21 ENST00000551744.2
ENST00000552283.1
nucleoporin 37kDa
chr17_-_10372875 0.20 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr7_+_6048856 0.20 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr12_+_2921788 0.19 ENST00000228799.2
ENST00000419778.2
ENST00000542548.1
integrin alpha FG-GAP repeat containing 2
chr3_-_105588231 0.19 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr11_-_111741994 0.19 ENST00000398006.2
ALG9, alpha-1,2-mannosyltransferase
chr15_-_75199213 0.19 ENST00000562698.1
family with sequence similarity 219, member B
chr4_+_128554081 0.18 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr8_+_94929077 0.18 ENST00000297598.4
ENST00000520614.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr8_+_26371763 0.18 ENST00000521913.1
dihydropyrimidinase-like 2
chr19_-_6424783 0.18 ENST00000398148.3
KH-type splicing regulatory protein
chr3_+_186288454 0.18 ENST00000265028.3
DnaJ (Hsp40) homolog, subfamily B, member 11
chr1_-_159915386 0.17 ENST00000361509.3
ENST00000368094.1
immunoglobulin superfamily, member 9
chr2_-_97405775 0.17 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
lectin, mannose-binding 2-like
chr8_+_94929168 0.16 ENST00000518107.1
ENST00000396200.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_57232525 0.16 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
spindle and kinetochore associated complex subunit 2
chr11_+_119205222 0.15 ENST00000311413.4
ring finger protein 26
chr15_-_64386120 0.15 ENST00000300030.3
family with sequence similarity 96, member A
chr4_-_103682145 0.15 ENST00000226578.4
mannosidase, beta A, lysosomal
chr3_+_57261743 0.15 ENST00000288266.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr11_+_72983246 0.14 ENST00000393590.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_+_99647389 0.14 ENST00000543588.1
ENST00000292450.4
ENST00000456748.2
zinc finger and SCAN domain containing 21
chr8_+_94929110 0.14 ENST00000520728.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_-_108507631 0.14 ENST00000527011.1
ENST00000370056.4
vav 3 guanine nucleotide exchange factor
chr5_+_150226085 0.13 ENST00000522154.1
immunity-related GTPase family, M
chr2_+_187371440 0.13 ENST00000445547.1
zinc finger CCCH-type containing 15
chr17_-_44657017 0.13 ENST00000573185.1
ENST00000570550.1
ENST00000445552.2
ENST00000336125.5
ENST00000329240.4
ENST00000337845.7
ADP-ribosylation factor-like 17A
chr11_-_118023594 0.12 ENST00000529878.1
sodium channel, voltage-gated, type IV, beta subunit
chr12_+_6961279 0.12 ENST00000229268.8
ENST00000389231.5
ENST00000542087.1
ubiquitin specific peptidase 5 (isopeptidase T)
chr17_-_61777459 0.12 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIM domain containing 2
chr17_-_44439084 0.12 ENST00000575960.1
ENST00000575698.1
ENST00000571246.1
ENST00000434041.2
ENST00000570618.1
ENST00000450673.3
ADP-ribosylation factor-like 17B
chrX_-_47509994 0.11 ENST00000343894.4
ELK1, member of ETS oncogene family
chr9_+_124329336 0.11 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr2_-_167232484 0.11 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
sodium channel, voltage-gated, type IX, alpha subunit
chr1_-_231004220 0.11 ENST00000366663.5
chromosome 1 open reading frame 198
chr3_+_23851928 0.11 ENST00000467766.1
ENST00000424381.1
ubiquitin-conjugating enzyme E2E 1
chr11_-_71823796 0.10 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr8_+_98656693 0.10 ENST00000519934.1
metadherin
chr15_-_64385981 0.10 ENST00000557835.1
ENST00000380290.3
ENST00000559950.1
family with sequence similarity 96, member A
chr19_+_45504688 0.10 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr1_+_222910625 0.10 ENST00000360827.2
family with sequence similarity 177, member B
chr11_-_4629388 0.10 ENST00000526337.1
ENST00000300747.5
tripartite motif containing 68
chr4_-_19458597 0.09 ENST00000505347.1
RP11-3J1.1
chr17_-_8113886 0.09 ENST00000577833.1
ENST00000534871.1
ENST00000583915.1
ENST00000316199.6
ENST00000581511.1
ENST00000585124.1
aurora kinase B
chr5_-_159546396 0.09 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP domain containing 2A
chr11_-_4629367 0.08 ENST00000533021.1
tripartite motif containing 68
chr11_-_71823715 0.08 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr6_-_85473073 0.07 ENST00000606621.1
T-box 18
chr19_+_36249057 0.06 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr1_+_46972668 0.06 ENST00000371956.4
ENST00000360032.3
diencephalon/mesencephalon homeobox 1
chr13_+_36050881 0.05 ENST00000537702.1
neurobeachin
chr7_-_27239703 0.05 ENST00000222753.4
homeobox A13
chr19_-_8070474 0.05 ENST00000407627.2
ENST00000593807.1
ELAV like RNA binding protein 1
chr16_-_66864806 0.05 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NEDD8 activating enzyme E1 subunit 1
chr11_-_105892937 0.05 ENST00000301919.4
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
chr10_-_56560939 0.04 ENST00000373955.1
protocadherin-related 15
chr8_+_98656336 0.04 ENST00000336273.3
metadherin
chr9_+_139780942 0.03 ENST00000247668.2
ENST00000359662.3
TNF receptor-associated factor 2
chrX_-_47509887 0.03 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1, member of ETS oncogene family
chrX_+_72783026 0.03 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr7_-_99716914 0.03 ENST00000431404.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_+_174843548 0.02 ENST00000478442.1
ENST00000465412.1
RAB GTPase activating protein 1-like
chr8_+_94929273 0.02 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_-_40337470 0.00 ENST00000293330.1
hypocretin (orexin) neuropeptide precursor

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.9 2.6 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.5 1.5 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 1.4 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.7 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.1 0.5 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.1 0.9 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.6 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.5 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.2 GO:0009405 pathogenesis(GO:0009405)
0.1 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.3 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.7 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158) regulation of miRNA metabolic process(GO:2000628)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 1.4 GO:0070187 telosome(GO:0070187)
0.1 9.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.6 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.6 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 1.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 GO:0043295 glutathione binding(GO:0043295)
0.2 0.9 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 2.6 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.6 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.5 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 0.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.6 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 0.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C