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Illumina Body Map 2: averaged replicates

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Results for NKX2-3

Z-value: 1.53

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Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
NKX2-3
ENSG00000119919.9 NK2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-3hg19_v2_chr10_+_101292684_1012927060.086.6e-01Click!

Activity profile of NKX2-3 motif

Sorted Z-values of NKX2-3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_71834207 2.73 ENST00000295619.3
PROK2
prokineticin 2
chr3_+_108541545 2.69 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr6_-_32731243 2.23 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr9_-_137809718 2.21 ENST00000371806.3
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr11_+_35211429 2.10 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr3_-_150966902 2.06 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr14_+_22788560 1.98 ENST00000390468.1
TRAV41
T cell receptor alpha variable 41
chrX_+_71354000 1.90 ENST00000510661.1
ENST00000535692.1
NHSL2
NHS-like 2
chr14_+_21423611 1.86 ENST00000304625.2
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr12_+_10460549 1.80 ENST00000543420.1
ENST00000543777.1
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chrX_+_71353499 1.76 ENST00000373677.1
NHSL2
NHS-like 2
chr7_-_76829125 1.65 ENST00000248598.5
FGL2
fibrinogen-like 2
chr19_-_44174330 1.65 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr12_-_123187890 1.65 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr13_-_45048386 1.65 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr12_+_9980113 1.64 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr20_-_4795747 1.64 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr12_-_123201337 1.63 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr10_+_129785574 1.63 ENST00000430713.2
ENST00000471218.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr4_-_90758227 1.58 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr4_-_90757364 1.55 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr3_+_108541608 1.54 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_+_10124110 1.53 ENST00000350667.4
CLEC12A
C-type lectin domain family 12, member A
chr1_+_40839369 1.53 ENST00000372718.3
SMAP2
small ArfGAP2
chr12_+_10124001 1.50 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr1_-_162381907 1.50 ENST00000367929.2
ENST00000359567.3
SH2D1B
SH2 domain containing 1B
chr16_-_89008211 1.48 ENST00000569464.1
ENST00000569443.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr10_-_5227096 1.48 ENST00000488756.1
ENST00000334314.3
AKR1CL1
aldo-keto reductase family 1, member C-like 1
chr14_+_21387491 1.44 ENST00000258817.2
RP11-84C10.2
RP11-84C10.2
chr6_-_112081113 1.39 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr19_-_14887568 1.34 ENST00000596991.2
ENST00000594294.1
ENST00000594076.1
ENST00000595839.1
ENST00000392965.3
ENST00000601345.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr14_+_22386325 1.34 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr4_-_84035868 1.33 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr6_-_32160622 1.32 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr5_+_17404114 1.32 ENST00000508677.1
RP11-321E2.3
RP11-321E2.3
chr4_-_90758118 1.30 ENST00000420646.2
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr19_+_3178736 1.30 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr10_+_129785536 1.29 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_-_15575369 1.27 ENST00000343625.7
RASAL3
RAS protein activator like 3
chr6_-_32731299 1.25 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr18_-_74839891 1.25 ENST00000581878.1
MBP
myelin basic protein
chr5_-_169739679 1.23 ENST00000511921.1
CTB-114C7.4
CTB-114C7.4
chr4_-_84035905 1.18 ENST00000311507.4
PLAC8
placenta-specific 8
chrX_+_153029633 1.18 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3
plexin B3
chr7_+_142326335 1.17 ENST00000390393.3
TRBV19
T cell receptor beta variable 19
chrX_+_9502971 1.17 ENST00000452824.1
TBL1X
transducin (beta)-like 1X-linked
chr5_-_142814241 1.16 ENST00000504572.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr18_-_5521372 1.15 ENST00000580989.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chrX_-_108976410 1.14 ENST00000504980.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr2_+_219110149 1.11 ENST00000456575.1
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr10_-_36813162 1.11 ENST00000440465.1
NAMPTL
nicotinamide phosphoribosyltransferase-like
chr7_-_37393263 1.09 ENST00000442504.1
ELMO1
engulfment and cell motility 1
chr14_+_22993296 1.09 ENST00000390517.1
TRAJ20
T cell receptor alpha joining 20
chr12_-_45315625 1.09 ENST00000552993.1
NELL2
NEL-like 2 (chicken)
chr6_+_46761118 1.08 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr17_-_29641084 1.08 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr3_+_186743261 1.07 ENST00000423451.1
ENST00000446170.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr19_+_14491948 1.06 ENST00000358600.3
CD97
CD97 molecule
chr7_-_29186008 1.06 ENST00000396276.3
ENST00000265394.5
CPVL
carboxypeptidase, vitellogenic-like
chr17_-_29641104 1.06 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr12_-_14849470 1.06 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr12_+_104982622 1.05 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr14_+_22580233 1.04 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr3_+_38179969 1.04 ENST00000396334.3
ENST00000417037.2
ENST00000424893.1
ENST00000495303.1
ENST00000443433.2
ENST00000421516.1
MYD88
myeloid differentiation primary response 88
chr20_+_48884002 1.04 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr15_+_57891609 1.03 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr22_-_50523807 1.01 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_+_10326612 1.00 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr19_+_14492247 0.99 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr12_+_10460417 0.99 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr14_+_21387508 0.99 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr1_+_207070775 0.99 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24
interleukin 24
chr17_+_58227287 0.99 ENST00000300900.4
ENST00000591725.1
CA4
carbonic anhydrase IV
chr19_+_14492217 0.98 ENST00000587606.1
ENST00000586517.1
ENST00000591080.1
CD97
CD97 molecule
chr14_+_64565442 0.97 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr18_-_70532906 0.97 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr19_-_45579762 0.96 ENST00000303809.2
ZNF296
zinc finger protein 296
chr3_-_36986534 0.96 ENST00000429976.2
ENST00000301807.6
TRANK1
tetratricopeptide repeat and ankyrin repeat containing 1
chr14_-_91720224 0.94 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr3_-_131753830 0.93 ENST00000429747.1
CPNE4
copine IV
chr19_-_29026154 0.93 ENST00000593065.1
AC005307.3
AC005307.3
chr3_-_150920979 0.91 ENST00000309180.5
ENST00000480322.1
GPR171
G protein-coupled receptor 171
chr1_+_174669653 0.90 ENST00000325589.5
RABGAP1L
RAB GTPase activating protein 1-like
chr8_+_32579271 0.90 ENST00000518084.1
NRG1
neuregulin 1
chr2_-_70944855 0.90 ENST00000415348.1
ADD2
adducin 2 (beta)
chr4_-_48082192 0.89 ENST00000507351.1
TXK
TXK tyrosine kinase
chr19_+_7445850 0.89 ENST00000593531.1
CTD-2207O23.3
Rho guanine nucleotide exchange factor 18
chr4_-_36246060 0.88 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr1_+_174670143 0.87 ENST00000367687.1
ENST00000347255.2
RABGAP1L
RAB GTPase activating protein 1-like
chrX_+_103029314 0.87 ENST00000429977.1
PLP1
proteolipid protein 1
chr10_+_106937525 0.86 ENST00000369699.4
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr18_-_67623906 0.86 ENST00000583955.1
CD226
CD226 molecule
chr2_-_158184211 0.85 ENST00000397283.2
ERMN
ermin, ERM-like protein
chr3_+_63428982 0.85 ENST00000479198.1
ENST00000460711.1
ENST00000465156.1
SYNPR
synaptoporin
chr4_-_85654615 0.85 ENST00000514711.1
WDFY3
WD repeat and FYVE domain containing 3
chr1_+_158901329 0.84 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chrX_-_108976449 0.83 ENST00000469857.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr15_+_43477580 0.83 ENST00000356633.5
CCNDBP1
cyclin D-type binding-protein 1
chr4_+_102734967 0.83 ENST00000444316.2
BANK1
B-cell scaffold protein with ankyrin repeats 1
chr19_+_36142147 0.82 ENST00000590618.1
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr18_+_22040620 0.81 ENST00000426880.2
HRH4
histamine receptor H4
chr21_+_30672433 0.81 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_38303218 0.80 ENST00000407341.1
ENST00000260630.3
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr6_-_137539651 0.79 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr18_-_67624160 0.79 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr12_-_108714412 0.78 ENST00000412676.1
ENST00000550573.1
CMKLR1
chemokine-like receptor 1
chrX_+_41548220 0.78 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr10_+_1120312 0.78 ENST00000436154.1
WDR37
WD repeat domain 37
chr13_+_32313658 0.78 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr2_+_89923550 0.77 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr4_+_81118647 0.76 ENST00000415738.2
PRDM8
PR domain containing 8
chr14_+_39703084 0.75 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr1_-_31538517 0.73 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chrX_+_41548259 0.73 ENST00000378138.5
GPR34
G protein-coupled receptor 34
chr14_+_22928070 0.72 ENST00000390476.1
TRDJ3
T cell receptor delta joining 3
chr19_+_41882466 0.72 ENST00000436170.2
TMEM91
transmembrane protein 91
chr2_+_191002486 0.72 ENST00000396974.2
C2orf88
chromosome 2 open reading frame 88
chr7_+_7196565 0.72 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_-_123565834 0.71 ENST00000546049.1
PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr3_+_30647994 0.70 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_-_156460391 0.70 ENST00000360595.3
MEF2D
myocyte enhancer factor 2D
chr15_+_43477455 0.69 ENST00000300213.4
CCNDBP1
cyclin D-type binding-protein 1
chr2_+_114163945 0.68 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chrX_-_108868390 0.68 ENST00000372101.2
KCNE1L
KCNE1-like
chr1_-_232598163 0.68 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr22_+_44427230 0.68 ENST00000444029.1
PARVB
parvin, beta
chr11_-_75017734 0.68 ENST00000532525.1
ARRB1
arrestin, beta 1
chr4_-_5990166 0.67 ENST00000324058.5
C4orf50
chromosome 4 open reading frame 50
chr2_+_191045173 0.67 ENST00000409870.1
C2orf88
chromosome 2 open reading frame 88
chr19_-_19051993 0.67 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr7_+_29186174 0.67 ENST00000439384.1
CHN2
chimerin 2
chr1_-_198990166 0.65 ENST00000427439.1
RP11-16L9.3
RP11-16L9.3
chr18_-_64271316 0.64 ENST00000540086.1
ENST00000580157.1
CDH19
cadherin 19, type 2
chr5_-_39270725 0.63 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr10_-_104262460 0.63 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr5_+_156693091 0.63 ENST00000318218.6
ENST00000442283.2
ENST00000522463.1
ENST00000521420.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr13_-_99910620 0.63 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr18_-_60986613 0.62 ENST00000444484.1
BCL2
B-cell CLL/lymphoma 2
chr3_-_160167301 0.62 ENST00000494486.1
TRIM59
tripartite motif containing 59
chr1_-_155880672 0.62 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr5_-_134783038 0.62 ENST00000503143.2
C5orf20
chromosome 5 open reading frame 20
chrX_+_103028638 0.61 ENST00000434483.1
PLP1
proteolipid protein 1
chr13_-_99910673 0.61 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr10_+_16478942 0.61 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER
phosphotriesterase related
chr11_+_64950801 0.61 ENST00000526468.1
CAPN1
calpain 1, (mu/I) large subunit
chr4_+_95376396 0.61 ENST00000508216.1
ENST00000514743.1
PDLIM5
PDZ and LIM domain 5
chr3_+_30648066 0.60 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr1_+_202317855 0.60 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr1_-_19746236 0.60 ENST00000375144.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr8_-_116673894 0.60 ENST00000395713.2
TRPS1
trichorhinophalangeal syndrome I
chr12_+_111537227 0.59 ENST00000397643.3
CUX2
cut-like homeobox 2
chr17_+_66521936 0.59 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr14_-_95624227 0.58 ENST00000526495.1
DICER1
dicer 1, ribonuclease type III
chrX_-_49121165 0.58 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr22_-_21213676 0.57 ENST00000449120.1
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_26216872 0.57 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chrX_-_134049233 0.56 ENST00000370779.4
MOSPD1
motile sperm domain containing 1
chr8_-_101719159 0.56 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr8_-_101718991 0.55 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr11_-_62342375 0.54 ENST00000378019.3
EEF1G
eukaryotic translation elongation factor 1 gamma
chr6_-_111927062 0.54 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr20_+_57427765 0.54 ENST00000371100.4
GNAS
GNAS complex locus
chr16_+_56969284 0.54 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr22_+_39101728 0.54 ENST00000216044.5
ENST00000484657.1
GTPBP1
GTP binding protein 1
chrX_-_14891150 0.53 ENST00000452869.1
ENST00000398334.1
ENST00000324138.3
FANCB
Fanconi anemia, complementation group B
chr5_+_162930114 0.53 ENST00000280969.5
MAT2B
methionine adenosyltransferase II, beta
chr8_-_135652051 0.53 ENST00000522257.1
ZFAT
zinc finger and AT hook domain containing
chr15_-_101142362 0.53 ENST00000559577.1
ENST00000561308.1
ENST00000560133.1
ENST00000560941.1
ENST00000559736.1
ENST00000560272.1
LINS
lines homolog (Drosophila)
chr5_-_70320941 0.52 ENST00000523981.1
NAIP
NLR family, apoptosis inhibitory protein
chr18_-_60985914 0.52 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr16_-_31076332 0.52 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr20_-_43729750 0.51 ENST00000537075.1
ENST00000306117.1
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr17_+_45286387 0.51 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr8_+_103540983 0.51 ENST00000523572.1
KB-1980E6.3
Uncharacterized protein
chr4_+_144303093 0.51 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr11_-_65363259 0.51 ENST00000342202.4
KCNK7
potassium channel, subfamily K, member 7
chr11_-_71753188 0.49 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr10_-_104262426 0.49 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr1_-_206306107 0.49 ENST00000436158.1
ENST00000455672.1
RP11-38J22.6
RP11-38J22.6
chr7_+_56032652 0.49 ENST00000437587.1
GBAS
glioblastoma amplified sequence
chr15_+_91411810 0.49 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr1_+_43803475 0.49 ENST00000372470.3
ENST00000413998.2
MPL
myeloproliferative leukemia virus oncogene
chr1_+_32666188 0.48 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr19_+_33865218 0.48 ENST00000585933.2
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr14_-_60636561 0.48 ENST00000536410.2
ENST00000216500.5
DHRS7
dehydrogenase/reductase (SDR family) member 7
chr3_+_23851928 0.48 ENST00000467766.1
ENST00000424381.1
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr4_-_57524061 0.48 ENST00000508121.1
HOPX
HOP homeobox
chr7_+_29186192 0.47 ENST00000539406.1
CHN2
chimerin 2
chr5_+_49961727 0.47 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_+_149569520 0.47 ENST00000230671.2
ENST00000524041.1
SLC6A7
solute carrier family 6 (neurotransmitter transporter), member 7
chr8_+_28196157 0.47 ENST00000522209.1
PNOC
prepronociceptin
chr5_-_59481406 0.47 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_22948510 0.47 ENST00000390483.1
TRAJ56
T cell receptor alpha joining 56
chr15_+_67841330 0.47 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr2_-_89597542 0.46 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr14_-_72458326 0.46 ENST00000542853.1
AC005477.1
AC005477.1
chr16_+_2255841 0.45 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr5_-_114631958 0.45 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr3_+_35721182 0.45 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_125398654 0.45 ENST00000541645.1
ENST00000540351.1
UBC
ubiquitin C

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.7 2.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.5 4.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.3 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.3 1.0 GO:0033037 polysaccharide localization(GO:0033037)
0.3 1.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.3 0.6 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.3 1.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.3 2.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.7 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.3 1.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.7 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.2 2.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.2 1.3 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 1.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 1.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 1.7 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.8 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.2 1.4 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 0.6 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.2 1.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.8 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.5 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 0.5 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 4.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.9 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 1.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.4 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 1.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.6 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.9 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 1.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.9 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.7 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.9 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 1.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 1.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 0.3 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.5 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.4 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 1.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.9 GO:0035973 aggrephagy(GO:0035973)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.3 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.8 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.1 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 1.3 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 1.5 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.1 0.3 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.6 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 1.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 2.6 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 1.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.6 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 1.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.9 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.7 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.3 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 2.6 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.8 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 4.5 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.4 GO:0032364 oxygen homeostasis(GO:0032364) hemoglobin biosynthetic process(GO:0042541)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 1.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.9 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.2 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.6 GO:0007614 short-term memory(GO:0007614)
0.0 0.3 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 1.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.6 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.9 GO:0001763 morphogenesis of a branching structure(GO:0001763)
0.0 0.8 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.3 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.6 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.3 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.2 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 1.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0051482 positive regulation of Rho protein signal transduction(GO:0035025) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 8.2 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 2.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.2 2.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 0.8 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.2 3.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.1 GO:0033269 internode region of axon(GO:0033269)
0.1 0.6 GO:0072534 perineuronal net(GO:0072534)
0.1 1.1 GO:0002177 manchette(GO:0002177)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 1.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 5.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0019034 viral replication complex(GO:0019034)
0.1 4.2 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.7 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.9 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.7 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.7 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 1.0 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.3 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 4.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.8 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0000322 storage vacuole(GO:0000322)
0.0 3.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 3.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 2.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.7 2.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.5 2.8 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 1.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.3 1.9 GO:0004522 ribonuclease A activity(GO:0004522)
0.2 1.7 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 3.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.0 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.2 2.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.7 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 1.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 0.5 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 1.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.1 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 4.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 1.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 2.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 1.6 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.1 0.5 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.3 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 0.7 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.6 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 1.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 2.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.8 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.3 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.4 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 1.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 7.5 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 1.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 2.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 3.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 5.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.0 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 4.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 2.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.0 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 6.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 3.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 3.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 5.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.2 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation