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Illumina Body Map 2: averaged replicates

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Results for NOTO_VSX2_DLX2_DLX6_NKX6-1

Z-value: 1.67

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Transcription factors associated with NOTO_VSX2_DLX2_DLX6_NKX6-1

Gene Symbol Gene ID Gene Info
NOTO
ENSG00000214513.3 notochord homeobox
VSX2
ENSG00000119614.2 visual system homeobox 2
DLX2
ENSG00000115844.6 distal-less homeobox 2
DLX6
ENSG00000006377.9 distal-less homeobox 6
NKX6-1
ENSG00000163623.5 NK6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-1hg19_v2_chr4_-_85418103_854181030.281.3e-01Click!
VSX2hg19_v2_chr14_+_74706150_747061750.163.7e-01Click!
DLX6hg19_v2_chr7_+_96635277_966353010.144.5e-01Click!
NOTOhg19_v2_chr2_+_73429386_73429386-0.086.5e-01Click!
DLX2hg19_v2_chr2_-_172967621_1729676370.048.5e-01Click!

Activity profile of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Sorted Z-values of NOTO_VSX2_DLX2_DLX6_NKX6-1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_10421853 8.71 ENST00000226207.5
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr6_-_87804815 7.67 ENST00000369582.2
CGA
glycoprotein hormones, alpha polypeptide
chr4_-_138453606 7.52 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr8_+_92261516 6.98 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr4_-_138453559 5.51 ENST00000511115.1
PCDH18
protocadherin 18
chr1_+_160160346 5.41 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr1_+_160160283 5.24 ENST00000368079.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr21_+_17442799 4.62 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr6_+_78400375 4.28 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr5_+_174151536 4.22 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr7_-_107642348 3.99 ENST00000393561.1
LAMB1
laminin, beta 1
chr12_-_16761007 3.97 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_+_24755416 3.97 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr14_-_36988882 3.91 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr7_-_27169801 3.80 ENST00000511914.1
HOXA4
homeobox A4
chr6_-_123958141 3.67 ENST00000334268.4
TRDN
triadin
chr10_+_123951957 3.62 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr12_+_81110684 3.58 ENST00000228644.3
MYF5
myogenic factor 5
chr7_+_73442487 3.46 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr6_-_123957942 3.27 ENST00000398178.3
TRDN
triadin
chr6_-_100912785 3.24 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr3_+_2933893 3.20 ENST00000397459.2
CNTN4
contactin 4
chr13_-_36050819 3.15 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr4_-_111563076 3.15 ENST00000354925.2
ENST00000511990.1
PITX2
paired-like homeodomain 2
chr17_+_59489112 3.08 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr17_-_77924627 3.04 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr20_-_50419055 2.98 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr8_+_121137333 2.90 ENST00000309791.4
ENST00000297848.3
ENST00000247781.3
COL14A1
collagen, type XIV, alpha 1
chr12_+_41831485 2.77 ENST00000539469.2
ENST00000298919.7
PDZRN4
PDZ domain containing ring finger 4
chr13_-_38172863 2.72 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr20_-_50418947 2.72 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr7_+_73442422 2.67 ENST00000358929.4
ENST00000431562.1
ENST00000320492.7
ENST00000438906.1
ELN
elastin
chr12_-_16761117 2.65 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_111563279 2.64 ENST00000511837.1
PITX2
paired-like homeodomain 2
chr12_+_54378923 2.61 ENST00000303460.4
HOXC10
homeobox C10
chr20_-_50418972 2.60 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr7_+_73442457 2.56 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN
elastin
chr6_-_123958051 2.45 ENST00000546248.1
TRDN
triadin
chr8_-_109799793 2.41 ENST00000297459.3
TMEM74
transmembrane protein 74
chr11_-_13517565 2.38 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr7_-_73038822 2.36 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr14_-_38064198 2.30 ENST00000250448.2
FOXA1
forkhead box A1
chr2_+_234826016 2.30 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr9_-_98189055 2.30 ENST00000433644.2
RP11-435O5.2
RP11-435O5.2
chr7_-_73038867 2.28 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr2_+_78143006 2.26 ENST00000443419.1
AC073628.1
AC073628.1
chr14_-_92413353 2.22 ENST00000556154.1
FBLN5
fibulin 5
chr2_-_183291741 2.22 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr7_+_73442102 2.17 ENST00000445912.1
ENST00000252034.7
ELN
elastin
chr8_-_42234745 2.11 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr18_+_76740189 2.10 ENST00000537592.2
ENST00000575389.2
SALL3
spalt-like transcription factor 3
chr11_+_65554493 2.10 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr4_-_186696425 2.09 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr6_+_4087664 2.06 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr1_-_95783809 2.06 ENST00000423410.1
RP4-586O15.1
RP4-586O15.1
chr1_-_234667504 2.03 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr6_-_123958111 2.02 ENST00000542443.1
TRDN
triadin
chr17_-_10452929 2.01 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr12_+_81101277 2.00 ENST00000228641.3
MYF6
myogenic factor 6 (herculin)
chr2_+_3800169 1.99 ENST00000399143.3
DCDC2C
doublecortin domain containing 2C
chr7_-_14029283 1.99 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr22_-_28490123 1.95 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr10_-_48416849 1.92 ENST00000249598.1
GDF2
growth differentiation factor 2
chr21_+_17443521 1.91 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_24298531 1.90 ENST00000175238.6
ADAM7
ADAM metallopeptidase domain 7
chr8_+_24298597 1.90 ENST00000380789.1
ADAM7
ADAM metallopeptidase domain 7
chr4_+_169418195 1.87 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr19_-_7698599 1.82 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr13_-_86373536 1.80 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_151034734 1.79 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr20_+_56136136 1.77 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr21_-_40033618 1.77 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr10_+_118083919 1.76 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chrX_+_99839799 1.74 ENST00000373031.4
TNMD
tenomodulin
chr14_-_92413727 1.74 ENST00000267620.10
FBLN5
fibulin 5
chr15_-_37393406 1.73 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr9_-_95166841 1.73 ENST00000262551.4
OGN
osteoglycin
chr9_-_95166976 1.72 ENST00000447356.1
OGN
osteoglycin
chr14_-_37051798 1.72 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr17_-_64225508 1.70 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_-_9694614 1.69 ENST00000330255.5
ENST00000571134.1
DHRS7C
dehydrogenase/reductase (SDR family) member 7C
chr6_-_76203454 1.69 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr3_-_157824292 1.67 ENST00000483851.2
SHOX2
short stature homeobox 2
chr5_-_1882858 1.65 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr3_+_148447887 1.64 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr5_-_56778635 1.63 ENST00000423391.1
ACTBL2
actin, beta-like 2
chr7_-_27179814 1.60 ENST00000522788.1
ENST00000521779.1
HOXA3
homeobox A3
chr21_+_17443434 1.59 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_77356248 1.58 ENST00000296043.6
SHROOM3
shroom family member 3
chr5_+_53751445 1.57 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr14_-_61116168 1.57 ENST00000247182.6
SIX1
SIX homeobox 1
chr9_-_95166884 1.56 ENST00000375561.5
OGN
osteoglycin
chr4_+_105828537 1.55 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr14_-_54423529 1.55 ENST00000245451.4
ENST00000559087.1
BMP4
bone morphogenetic protein 4
chr7_-_107443652 1.52 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr8_-_42358742 1.52 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr1_+_214161272 1.47 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr2_-_180610767 1.40 ENST00000409343.1
ZNF385B
zinc finger protein 385B
chr15_-_54025300 1.38 ENST00000559418.1
WDR72
WD repeat domain 72
chr7_-_14029515 1.35 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr11_-_26593649 1.34 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr6_-_76203345 1.32 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr17_-_46671323 1.32 ENST00000239151.5
HOXB5
homeobox B5
chr17_-_38938786 1.31 ENST00000301656.3
KRT27
keratin 27
chr12_-_16430619 1.30 ENST00000344941.3
SLC15A5
solute carrier family 15, member 5
chr8_+_77593474 1.29 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr12_-_16759440 1.29 ENST00000537304.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_186696515 1.29 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_152589670 1.27 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr21_-_31864275 1.26 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr11_-_26593779 1.26 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr12_-_6233828 1.25 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr4_-_186696561 1.22 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr1_+_61547894 1.21 ENST00000403491.3
NFIA
nuclear factor I/A
chr1_+_160370344 1.21 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chrX_+_105937068 1.21 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chrX_-_10851762 1.20 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_24298438 1.19 ENST00000441335.2
ADAM7
ADAM metallopeptidase domain 7
chr4_+_41614909 1.18 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr11_-_16419067 1.16 ENST00000533411.1
SOX6
SRY (sex determining region Y)-box 6
chr11_-_26593677 1.15 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr2_+_176987088 1.15 ENST00000249499.6
HOXD9
homeobox D9
chr4_+_71494461 1.15 ENST00000396073.3
ENAM
enamelin
chrX_+_43515467 1.14 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr4_+_169013666 1.14 ENST00000359299.3
ANXA10
annexin A10
chrX_-_106243451 1.13 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr5_+_31193847 1.13 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr12_-_16759711 1.13 ENST00000447609.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_74486217 1.12 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_71108300 1.12 ENST00000304954.3
CSN3
casein kappa
chr11_-_2160180 1.11 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_31107127 1.10 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_+_159557637 1.10 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr12_+_108168162 1.09 ENST00000342331.4
ASCL4
achaete-scute family bHLH transcription factor 4
chr12_-_102874330 1.08 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_176811431 1.08 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr6_+_105404899 1.08 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr17_+_68071389 1.07 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_178840157 1.05 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr19_-_7697857 1.04 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr2_+_171571827 1.04 ENST00000375281.3
SP5
Sp5 transcription factor
chr4_+_183065793 1.03 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr1_-_94586651 1.01 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr2_-_171571077 1.01 ENST00000409786.1
AC007405.2
long intergenic non-protein coding RNA 1124
chr9_+_130026756 1.01 ENST00000314904.5
ENST00000373387.4
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr6_+_118869452 1.01 ENST00000357525.5
PLN
phospholamban
chr3_-_120400960 1.01 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chrX_+_105936982 1.00 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr12_-_86650045 1.00 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_76072719 1.00 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr12_-_28123206 1.00 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr13_-_36788718 0.99 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr3_+_2553281 0.99 ENST00000434053.1
CNTN4
contactin 4
chr12_+_26348582 0.98 ENST00000535504.1
SSPN
sarcospan
chr10_-_33623310 0.98 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1
neuropilin 1
chr8_+_77593448 0.98 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr1_-_159832438 0.98 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr1_+_68150744 0.97 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr12_+_52695617 0.96 ENST00000293525.5
KRT86
keratin 86
chr14_+_38065052 0.95 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr2_+_171034646 0.95 ENST00000409044.3
ENST00000408978.4
MYO3B
myosin IIIB
chr4_-_74486109 0.94 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_+_54378849 0.94 ENST00000515593.1
HOXC10
homeobox C10
chr4_+_151503077 0.93 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr10_-_102989551 0.93 ENST00000370193.2
LBX1
ladybird homeobox 1
chr17_+_48243352 0.93 ENST00000344627.6
ENST00000262018.3
ENST00000543315.1
ENST00000451235.2
ENST00000511303.1
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
chr6_+_151646800 0.93 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_28122980 0.93 ENST00000395868.3
ENST00000534890.1
PTHLH
parathyroid hormone-like hormone
chr12_+_18414446 0.92 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr11_-_8290263 0.92 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr3_-_57233966 0.91 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr1_-_185597619 0.91 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
GS1-204I12.1
chr1_-_57045228 0.91 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_88571429 0.91 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr20_+_42187682 0.91 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr13_+_110958124 0.91 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr10_+_119302508 0.91 ENST00000442245.4
EMX2
empty spiracles homeobox 2
chr14_-_54425475 0.91 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr12_-_16760021 0.91 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_49834299 0.90 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr9_-_16253112 0.90 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr14_-_95236551 0.89 ENST00000238558.3
GSC
goosecoid homeobox
chr8_-_101661887 0.89 ENST00000311812.2
SNX31
sorting nexin 31
chrX_-_139047669 0.88 ENST00000370540.1
CXorf66
chromosome X open reading frame 66
chr12_-_71031185 0.87 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_+_119809984 0.87 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr15_-_90222610 0.87 ENST00000300055.5
PLIN1
perilipin 1
chrX_-_110507098 0.87 ENST00000541758.1
CAPN6
calpain 6
chr15_-_90222642 0.86 ENST00000430628.2
PLIN1
perilipin 1
chr17_-_46690839 0.86 ENST00000498634.2
HOXB8
homeobox B8
chr15_-_98836406 0.86 ENST00000560360.1
CTD-2544M6.1
CTD-2544M6.1
chr12_-_86650077 0.85 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr7_+_116660246 0.85 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr8_+_22424551 0.85 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr4_+_119810134 0.85 ENST00000434046.2
SYNPO2
synaptopodin 2
chr22_-_32860427 0.84 ENST00000534972.1
ENST00000397450.1
ENST00000397452.1
BPIFC
BPI fold containing family C
chr17_-_10372875 0.83 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr4_-_74486347 0.82 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_7167279 0.81 ENST00000571932.2
CLDN7
claudin 7
chr5_-_126409159 0.81 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63

Network of associatons between targets according to the STRING database.

First level regulatory network of NOTO_VSX2_DLX2_DLX6_NKX6-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.4 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
1.4 4.2 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
1.2 5.8 GO:0060127 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.8 10.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.8 11.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.8 4.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.8 2.4 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.8 1.6 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.8 2.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.7 2.2 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.7 4.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.6 3.0 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.6 4.2 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.6 1.7 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 1.6 GO:0010159 specification of organ position(GO:0010159)
0.5 2.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.5 7.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.5 2.5 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.5 8.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 9.2 GO:0019532 oxalate transport(GO:0019532)
0.5 2.7 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.4 1.8 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.4 1.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.4 1.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 4.6 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 1.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.4 4.4 GO:0021759 globus pallidus development(GO:0021759)
0.4 1.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.4 2.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.3 1.7 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.3 1.0 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.3 2.3 GO:0050955 thermoception(GO:0050955)
0.3 1.8 GO:0060005 vestibular reflex(GO:0060005)
0.3 0.9 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 3.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 2.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.3 1.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.3 GO:0007525 somatic muscle development(GO:0007525)
0.3 0.8 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.7 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.2 0.9 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.2 0.4 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.2 3.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 5.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.2 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2 1.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 1.0 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.2 0.6 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 0.8 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 1.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 0.7 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.2 0.5 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.2 0.8 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.2 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 3.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.2 0.6 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 4.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 2.2 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.2 0.6 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 0.5 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.7 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 1.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.8 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 2.6 GO:0072189 ureter development(GO:0072189)
0.1 0.8 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.8 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 2.0 GO:0001778 plasma membrane repair(GO:0001778)
0.1 7.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.1 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.5 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 1.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 5.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.8 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 1.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 4.0 GO:0007413 axonal fasciculation(GO:0007413)
0.1 10.9 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 2.4 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.8 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 0.9 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 2.9 GO:0002076 osteoblast development(GO:0002076)
0.1 1.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.5 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 1.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.9 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.2 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.1 0.5 GO:0048619 hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.5 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 0.3 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 1.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 1.4 GO:0097264 self proteolysis(GO:0097264)
0.1 1.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 2.8 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 1.0 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 11.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.5 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.7 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.2 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.3 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 1.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.5 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 1.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.7 GO:0060539 diaphragm development(GO:0060539)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.5 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.1 GO:0010107 potassium ion import(GO:0010107)
0.0 1.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 1.1 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 3.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.0 1.3 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 2.9 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 1.7 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0016264 gap junction assembly(GO:0016264)
0.0 1.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 2.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.2 GO:0032525 negative regulation of neuron maturation(GO:0014043) somite rostral/caudal axis specification(GO:0032525)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.3 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.6 GO:0008542 visual learning(GO:0008542)
0.0 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 2.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 2.6 GO:0070268 cornification(GO:0070268)
0.0 0.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.7 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 1.3 GO:0007595 lactation(GO:0007595)
0.0 1.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.5 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.9 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.5 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 1.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 1.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 22.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.3 14.8 GO:0071953 elastic fiber(GO:0071953)
1.3 4.0 GO:0043257 laminin-8 complex(GO:0043257)
0.6 2.9 GO:0030934 anchoring collagen complex(GO:0030934)
0.4 3.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4 12.2 GO:0032982 myosin filament(GO:0032982)
0.3 1.2 GO:0060187 cell pole(GO:0060187)
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 3.5 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.2 0.7 GO:1990032 parallel fiber(GO:1990032)
0.2 4.3 GO:0000800 lateral element(GO:0000800)
0.1 3.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.7 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 1.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 17.1 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.9 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.9 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 7.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 1.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 2.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 6.1 GO:0005882 intermediate filament(GO:0005882)
0.0 8.8 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0031674 I band(GO:0031674)
0.0 3.9 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0032997 Fc receptor complex(GO:0032997) Fc-epsilon receptor I complex(GO:0032998)
0.0 5.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.3 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)
0.0 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 4.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0005921 gap junction(GO:0005921)
0.0 7.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 1.7 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 3.0 GO:0030496 midbody(GO:0030496)
0.0 5.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0042175 endoplasmic reticulum membrane(GO:0005789) nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 2.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 1.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.5 9.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.3 2.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 2.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.3 0.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 2.2 GO:0050692 DBD domain binding(GO:0050692)
0.2 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 4.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 0.6 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 2.9 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 0.6 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.2 0.7 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.5 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 1.5 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 6.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.6 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 0.5 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.8 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.2 1.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 0.5 GO:0097689 iron channel activity(GO:0097689)
0.1 0.4 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.1 0.4 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.5 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 16.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.5 GO:0004802 transketolase activity(GO:0004802)
0.1 4.7 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.4 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 4.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 3.4 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 1.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.5 GO:0001047 core promoter binding(GO:0001047)
0.1 1.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 2.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 11.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0001093 TFIIB-class transcription factor binding(GO:0001093)
0.0 5.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 3.3 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 1.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 10.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 6.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 6.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0003796 lysozyme activity(GO:0003796)
0.0 5.7 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 3.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.0 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.0 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 29.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 4.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 2.5 GO:0008083 growth factor activity(GO:0008083)
0.0 2.9 GO:0016779 nucleotidyltransferase activity(GO:0016779)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 2.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0032093 SAM domain binding(GO:0032093)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 6.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 8.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 11.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 4.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 7.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 17.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 3.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 3.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 3.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 5.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 3.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.8 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 5.9 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 3.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.8 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors