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Illumina Body Map 2: averaged replicates

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Results for NR2C1

Z-value: 1.59

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Transcription factors associated with NR2C1

Gene Symbol Gene ID Gene Info
NR2C1
ENSG00000120798.12 nuclear receptor subfamily 2 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C1hg19_v2_chr12_-_95467267_954673500.048.2e-01Click!

Activity profile of NR2C1 motif

Sorted Z-values of NR2C1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_229569834 8.51 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr17_+_37821593 6.33 ENST00000578283.1
TCAP
titin-cap
chr17_+_4853442 5.65 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr16_-_4292071 5.52 ENST00000399609.3
SRL
sarcalumenin
chr1_-_917466 5.36 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr9_-_35685452 4.95 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr14_-_65289812 4.61 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
SPTB
spectrin, beta, erythrocytic
chr1_+_160097462 4.48 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr14_+_105212297 4.45 ENST00000556623.1
ENST00000555674.1
ADSSL1
adenylosuccinate synthase like 1
chr12_+_48499883 4.38 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr22_+_31518938 4.24 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr18_+_7231123 4.05 ENST00000383467.2
LRRC30
leucine rich repeat containing 30
chrX_+_38420623 3.82 ENST00000378482.2
TSPAN7
tetraspanin 7
chr6_+_133561725 3.77 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chrX_+_38420783 3.54 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr4_-_111544254 3.48 ENST00000306732.3
PITX2
paired-like homeodomain 2
chr22_-_50699701 3.40 ENST00000395780.1
MAPK12
mitogen-activated protein kinase 12
chr19_-_48867171 3.32 ENST00000377431.2
ENST00000436660.2
ENST00000541566.1
TMEM143
transmembrane protein 143
chr19_-_48867291 3.17 ENST00000435956.3
TMEM143
transmembrane protein 143
chr19_+_16771936 3.04 ENST00000187762.2
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr4_-_111544207 2.90 ENST00000557119.2
PITX2
paired-like homeodomain 2
chr15_-_43863695 2.85 ENST00000439195.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr19_-_51289436 2.75 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr6_-_160148356 2.50 ENST00000401980.3
ENST00000545162.1
SOD2
superoxide dismutase 2, mitochondrial
chr3_+_37284824 2.49 ENST00000431105.1
GOLGA4
golgin A4
chr3_-_58613323 2.38 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr3_+_159557637 2.36 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr10_+_24755416 2.33 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr14_-_73360796 2.14 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr11_+_94501497 2.12 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr15_+_65369082 2.11 ENST00000432196.2
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr6_-_160147925 1.95 ENST00000535561.1
SOD2
superoxide dismutase 2, mitochondrial
chr10_-_118502070 1.88 ENST00000369209.3
HSPA12A
heat shock 70kDa protein 12A
chr8_-_80680078 1.87 ENST00000337919.5
ENST00000354724.3
HEY1
hes-related family bHLH transcription factor with YRPW motif 1
chr15_-_83474806 1.79 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr15_-_65715401 1.78 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr12_+_109577202 1.78 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr17_+_13972807 1.72 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr9_-_33402506 1.72 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr10_+_63808970 1.72 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr13_-_33760216 1.67 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_+_64073699 1.64 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr11_+_131781290 1.62 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr8_+_96037205 1.59 ENST00000396124.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr2_-_163099546 1.49 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr1_+_44412577 1.49 ENST00000372343.3
IPO13
importin 13
chr3_+_37284668 1.49 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
GOLGA4
golgin A4
chr7_-_229557 1.45 ENST00000514988.1
AC145676.2
Uncharacterized protein
chr11_+_10471836 1.39 ENST00000444303.2
AMPD3
adenosine monophosphate deaminase 3
chr14_-_21492251 1.36 ENST00000554398.1
NDRG2
NDRG family member 2
chr6_+_31515337 1.30 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr2_+_202316392 1.27 ENST00000194530.3
ENST00000392249.2
STRADB
STE20-related kinase adaptor beta
chr8_-_145028013 1.27 ENST00000354958.2
PLEC
plectin
chr22_-_38851205 1.26 ENST00000303592.3
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr5_+_1801503 1.24 ENST00000274137.5
ENST00000469176.1
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr8_+_96037255 1.24 ENST00000286687.4
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr2_-_163099885 1.22 ENST00000443424.1
FAP
fibroblast activation protein, alpha
chr4_+_159593418 1.21 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr11_+_111896090 1.11 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr3_-_116164306 1.06 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr1_+_215255136 1.06 ENST00000478774.1
KCNK2
potassium channel, subfamily K, member 2
chr15_+_91449971 1.06 ENST00000557865.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr19_+_51293672 1.06 ENST00000270593.1
ENST00000270594.3
ACPT
acid phosphatase, testicular
chr13_+_103046954 1.04 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr2_-_163100045 1.03 ENST00000188790.4
FAP
fibroblast activation protein, alpha
chr11_+_111896320 0.98 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr14_-_21492113 0.96 ENST00000554094.1
NDRG2
NDRG family member 2
chr19_-_49371711 0.94 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr11_+_67798090 0.91 ENST00000313468.5
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr3_-_50605150 0.90 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr12_-_124873357 0.89 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr8_+_70404996 0.87 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chrX_-_128657457 0.87 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr15_+_82555125 0.81 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr18_+_8609402 0.78 ENST00000329286.6
RAB12
RAB12, member RAS oncogene family
chr10_-_23633720 0.77 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr3_+_46538981 0.71 ENST00000296142.3
RTP3
receptor (chemosensory) transporter protein 3
chr11_-_64013288 0.70 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr20_-_30458432 0.70 ENST00000375966.4
ENST00000278979.3
DUSP15
dual specificity phosphatase 15
chr20_-_44485835 0.69 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr22_+_39745930 0.69 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chr2_+_109237717 0.69 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr10_+_104005272 0.66 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr6_+_43737939 0.64 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr19_-_51472031 0.62 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr22_+_41777927 0.61 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr8_-_80942467 0.57 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr3_+_154801312 0.57 ENST00000497890.1
MME
membrane metallo-endopeptidase
chr3_-_50605077 0.57 ENST00000426034.1
ENST00000441239.1
C3orf18
chromosome 3 open reading frame 18
chr3_+_150264555 0.56 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chrX_-_132095419 0.53 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr1_+_45140400 0.53 ENST00000453711.1
C1orf228
chromosome 1 open reading frame 228
chr3_+_154801678 0.51 ENST00000462837.1
MME
membrane metallo-endopeptidase
chr2_-_219134343 0.51 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr3_+_184055240 0.51 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr9_-_139839064 0.51 ENST00000325285.3
ENST00000428398.1
FBXW5
F-box and WD repeat domain containing 5
chr3_+_150264458 0.50 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr11_-_64013663 0.50 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_-_205419053 0.49 ENST00000367154.1
LEMD1
LEM domain containing 1
chr6_+_160148593 0.46 ENST00000337387.4
WTAP
Wilms tumor 1 associated protein
chr2_+_151485403 0.45 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
AC104777.4
AC104777.4
chr2_+_201936458 0.45 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr18_-_54318353 0.45 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr2_+_210636697 0.45 ENST00000439458.1
ENST00000272845.6
UNC80
unc-80 homolog (C. elegans)
chr11_+_7595136 0.44 ENST00000529575.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr13_+_21714653 0.42 ENST00000382533.4
SAP18
Sin3A-associated protein, 18kDa
chr16_-_88752889 0.42 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr2_+_201936707 0.42 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr16_+_83932684 0.42 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr22_-_31536480 0.41 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr19_-_41256207 0.40 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr22_+_30163340 0.39 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr9_-_16253112 0.37 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr11_-_26743546 0.36 ENST00000280467.6
ENST00000396005.3
SLC5A12
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_-_226374373 0.35 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr3_-_116163830 0.35 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr11_-_65429891 0.35 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr20_+_19870167 0.35 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr6_+_57037089 0.34 ENST00000370693.5
BAG2
BCL2-associated athanogene 2
chr15_-_82555000 0.34 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1
elongation factor Tu GTP binding domain containing 1
chr14_+_74035763 0.32 ENST00000238651.5
ACOT2
acyl-CoA thioesterase 2
chr2_+_109745655 0.32 ENST00000418513.1
SH3RF3
SH3 domain containing ring finger 3
chr1_-_120439112 0.31 ENST00000369400.1
ADAM30
ADAM metallopeptidase domain 30
chr13_+_21714711 0.28 ENST00000607003.1
ENST00000492245.1
SAP18
Sin3A-associated protein, 18kDa
chr5_-_42811986 0.27 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr11_+_67798363 0.27 ENST00000525628.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr15_+_45422178 0.26 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr15_+_45422131 0.26 ENST00000321429.4
DUOX1
dual oxidase 1
chr6_+_10585979 0.24 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_1801408 0.24 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr11_+_67798114 0.24 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr22_+_47158578 0.23 ENST00000355704.3
TBC1D22A
TBC1 domain family, member 22A
chr19_-_36054555 0.22 ENST00000262623.3
ATP4A
ATPase, H+/K+ exchanging, alpha polypeptide
chr4_-_76598296 0.21 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr15_-_45422056 0.20 ENST00000267803.4
ENST00000559014.1
ENST00000558851.1
ENST00000559988.1
ENST00000558996.1
ENST00000558422.1
ENST00000559226.1
ENST00000558326.1
ENST00000558377.1
ENST00000559644.1
DUOXA1
dual oxidase maturation factor 1
chr11_+_123810250 0.18 ENST00000307033.2
OR4D5
olfactory receptor, family 4, subfamily D, member 5
chr2_-_96701722 0.18 ENST00000434632.1
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_+_142749417 0.16 ENST00000418316.1
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr16_+_2255710 0.15 ENST00000397124.1
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr1_-_45140074 0.15 ENST00000420706.1
ENST00000372235.3
ENST00000372242.3
ENST00000372243.3
ENST00000372244.3
TMEM53
transmembrane protein 53
chr9_-_34397800 0.15 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr12_-_109219937 0.15 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr4_-_76598326 0.14 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr9_+_33795533 0.13 ENST00000379405.3
PRSS3
protease, serine, 3
chr14_+_74003818 0.12 ENST00000311148.4
ACOT1
acyl-CoA thioesterase 1
chr12_-_54070098 0.12 ENST00000394349.3
ENST00000549164.1
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr10_+_127661942 0.10 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr9_-_140513231 0.09 ENST00000371417.3
C9orf37
chromosome 9 open reading frame 37
chr1_+_212797789 0.09 ENST00000294829.3
FAM71A
family with sequence similarity 71, member A
chr16_+_2255841 0.08 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr7_+_121513143 0.08 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr19_-_46142362 0.07 ENST00000586770.1
ENST00000591721.1
EML2
echinoderm microtubule associated protein like 2
chr12_-_53729525 0.06 ENST00000303846.3
SP7
Sp7 transcription factor
chr3_+_179065474 0.06 ENST00000471841.1
ENST00000280653.7
MFN1
mitofusin 1
chr12_-_42631529 0.05 ENST00000548917.1
YAF2
YY1 associated factor 2
chr13_+_21714913 0.05 ENST00000450573.1
ENST00000467636.1
SAP18
Sin3A-associated protein, 18kDa
chr16_-_70729496 0.04 ENST00000567648.1
VAC14
Vac14 homolog (S. cerevisiae)
chr11_-_63684316 0.04 ENST00000301459.4
RCOR2
REST corepressor 2
chr3_+_183903811 0.02 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr2_-_219134822 0.01 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr2_+_46926326 0.01 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr2_+_33701707 0.01 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_219433014 0.00 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
1.4 8.5 GO:0090131 mesenchyme migration(GO:0090131)
1.3 6.4 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
1.2 3.7 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.9 6.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.9 4.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.9 4.4 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.7 4.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.7 2.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5 1.9 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.3 2.2 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.3 0.9 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3 1.7 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.6 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.4 GO:0006196 AMP catabolic process(GO:0006196)
0.2 3.8 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 1.7 GO:0015793 glycerol transport(GO:0015793)
0.2 0.7 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 3.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 2.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 4.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 4.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.1 2.1 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 2.2 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 5.6 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.1 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 6.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.7 GO:0008535 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) respiratory chain complex IV assembly(GO:0008535)
0.1 0.5 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 5.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 1.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 4.6 GO:0051693 actin filament capping(GO:0051693)
0.1 0.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 1.3 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.7 GO:0016559 peroxisome fission(GO:0016559)
0.0 1.7 GO:0016577 histone demethylation(GO:0016577)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 1.3 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 1.6 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 1.6 GO:0008038 neuron recognition(GO:0008038)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.7 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.7 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.0 2.3 GO:0048706 embryonic skeletal system development(GO:0048706)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.5 4.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.5 2.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 5.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 5.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 8.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 4.6 GO:0008091 spectrin(GO:0008091)
0.2 3.7 GO:0071438 invadopodium membrane(GO:0071438)
0.2 4.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 1.1 GO:0044305 calyx of Held(GO:0044305)
0.1 0.9 GO:0016589 NURF complex(GO:0016589)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.1 2.1 GO:0071565 nBAF complex(GO:0071565)
0.1 2.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 3.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 3.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 4.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 5.6 GO:0030018 Z disc(GO:0030018)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
1.1 6.3 GO:0051373 FATZ binding(GO:0051373)
0.7 2.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.6 5.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 4.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.5 1.9 GO:0035939 microsatellite binding(GO:0035939)
0.4 4.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 1.2 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.4 2.9 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 1.7 GO:0015254 glycerol channel activity(GO:0015254)
0.3 4.2 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 1.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 4.5 GO:1990239 steroid hormone binding(GO:1990239)
0.2 1.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.2 1.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 5.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 1.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 8.5 GO:0043531 ADP binding(GO:0043531)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 3.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 3.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 3.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 6.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.9 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 3.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 1.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 5.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 6.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 8.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 4.4 PID FOXO PATHWAY FoxO family signaling
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 4.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 10.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 11.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 4.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 4.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 1.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway