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Illumina Body Map 2: averaged replicates
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Results for NR2F1
Z-value: 1.65
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Transcription factors associated with NR2F1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR2F1 | hg19_v2_chr5_+_92919043_92919082 | 0.05 | 7.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of NR2F1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 11.9 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 1.4 | 9.9 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 2.3 | 9.0 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 1.2 | 8.5 | GO:0030300 | regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729) |
| 2.0 | 8.0 | GO:0035565 | regulation of pronephros size(GO:0035565) |
| 0.3 | 7.7 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.3 | 7.1 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.6 | 6.7 | GO:0019344 | cysteine biosynthetic process(GO:0019344) |
| 0.4 | 6.7 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.0 | 6.0 | GO:0030449 | regulation of complement activation(GO:0030449) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 39.2 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 13.1 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.5 | 12.4 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 8.6 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.1 | 7.3 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 7.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.5 | 6.0 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.7 | 5.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.1 | 4.1 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 3.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 15.3 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.1 | 12.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 2.3 | 9.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.1 | 8.5 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.3 | 8.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.8 | 8.2 | GO:0005497 | androgen binding(GO:0005497) |
| 0.4 | 7.4 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 0.1 | 7.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 6.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.8 | 5.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 22.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 13.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 8.6 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 8.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 8.2 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 2.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.5 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.2 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 1.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.4 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 21.8 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.6 | 17.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.7 | 15.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.2 | 9.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.6 | 8.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.1 | 7.2 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 7.1 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 6.3 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.4 | 6.0 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 5.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |