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Illumina Body Map 2: averaged replicates

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Results for NR2F1

Z-value: 1.65

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Transcription factors associated with NR2F1

Gene Symbol Gene ID Gene Info
ENSG00000175745.7 nuclear receptor subfamily 2 group F member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2F1hg19_v2_chr5_+_92919043_929190820.057.8e-01Click!

Activity profile of NR2F1 motif

Sorted Z-values of NR2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_173886491 7.70 ENST00000367698.3
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr11_-_116708302 5.13 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr3_-_42917363 4.86 ENST00000437102.1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr16_+_56685796 4.75 ENST00000334346.2
ENST00000562399.1
metallothionein 1B
chr20_+_56136136 4.71 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr10_-_129691195 4.66 ENST00000368671.3
clarin 3
chr17_+_1646130 4.55 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_+_196857144 4.53 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr11_-_116663127 4.41 ENST00000433069.1
ENST00000542499.1
apolipoprotein A-V
chrX_+_138612889 4.38 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr10_-_96829246 4.25 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr11_-_116694009 4.10 ENST00000357780.3
apolipoprotein A-IV
chr20_-_7921090 4.03 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr10_+_96443378 3.96 ENST00000285979.6
cytochrome P450, family 2, subfamily C, polypeptide 18
chr1_-_161193349 3.90 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
apolipoprotein A-II
chr10_+_96443204 3.80 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr3_+_46538981 3.72 ENST00000296142.3
receptor (chemosensory) transporter protein 3
chr17_-_36105009 3.62 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1 homeobox B
chr4_+_69962185 3.59 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr17_+_7531281 3.56 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr10_-_74714533 3.54 ENST00000373032.3
phospholipase A2, group XIIB
chr4_+_69962212 3.51 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr17_+_7533439 3.40 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
sex hormone-binding globulin
chr1_+_196946680 3.35 ENST00000256785.4
complement factor H-related 5
chr1_+_196946664 3.32 ENST00000367414.5
complement factor H-related 5
chr7_-_99277610 3.30 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
cytochrome P450, family 3, subfamily A, polypeptide 5
chr6_+_30130969 3.09 ENST00000376694.4
tripartite motif containing 15
chr10_-_54531406 3.09 ENST00000373968.3
mannose-binding lectin (protein C) 2, soluble
chrX_+_106163626 3.00 ENST00000336803.1
claudin 2
chr1_-_11107280 2.94 ENST00000400897.3
ENST00000400898.3
mannan-binding lectin serine peptidase 2
chr1_-_169555779 2.90 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr3_+_113616317 2.84 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr19_-_51017127 2.79 ENST00000389208.4
aspartate dehydrogenase domain containing
chr14_+_103573853 2.71 ENST00000560304.1
exocyst complex component 3-like 4
chr22_+_25003626 2.70 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
gamma-glutamyltransferase 1
chr1_-_155270770 2.70 ENST00000392414.3
pyruvate kinase, liver and RBC
chr20_-_7238861 2.62 ENST00000428954.1
RP11-19D2.1
chr4_+_100495864 2.62 ENST00000265517.5
ENST00000422897.2
microsomal triglyceride transfer protein
chr17_+_27071002 2.54 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TNF receptor-associated factor 4
chr12_-_21757774 2.51 ENST00000261195.2
glycogen synthase 2 (liver)
chr1_-_55089191 2.46 ENST00000302250.2
ENST00000371304.2
family with sequence similarity 151, member A
chr19_-_36304201 2.44 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr1_-_155271213 2.39 ENST00000342741.4
pyruvate kinase, liver and RBC
chr19_-_59023348 2.35 ENST00000601355.1
ENST00000263093.2
solute carrier family 27 (fatty acid transporter), member 5
chr7_-_99332719 2.34 ENST00000336374.2
cytochrome P450, family 3, subfamily A, polypeptide 7
chr2_-_169887827 2.29 ENST00000263817.6
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr1_+_16068917 2.28 ENST00000375782.1
transmembrane protein 82
chr2_+_228678550 2.25 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr19_+_5823813 2.24 ENST00000303212.2
neurturin
chr10_+_96522361 2.21 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr10_+_101542462 2.19 ENST00000370449.4
ENST00000370434.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr12_-_14996355 2.17 ENST00000228936.4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr17_-_34329084 2.15 ENST00000354059.4
ENST00000536149.1
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr10_-_91403625 2.10 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
pantothenate kinase 1
chr12_+_121416489 2.09 ENST00000541395.1
ENST00000544413.1
HNF1 homeobox A
chr22_+_25003606 2.08 ENST00000432867.1
gamma-glutamyltransferase 1
chr1_+_171060018 2.06 ENST00000367755.4
ENST00000392085.2
ENST00000542847.1
ENST00000538429.1
ENST00000479749.1
flavin containing monooxygenase 3
chr17_-_34345002 2.04 ENST00000293280.2
chemokine (C-C motif) ligand 23
chr2_-_28113217 2.00 ENST00000444339.2
ribokinase
chr17_-_7531121 1.99 ENST00000573566.1
ENST00000269298.5
spermidine/spermine N1-acetyltransferase family member 2
chr1_-_169555709 1.98 ENST00000546081.1
coagulation factor V (proaccelerin, labile factor)
chr1_-_203144941 1.95 ENST00000255416.4
myosin binding protein H
chr22_+_25003568 1.91 ENST00000447416.1
gamma-glutamyltransferase 1
chr19_+_41594377 1.90 ENST00000330436.3
cytochrome P450, family 2, subfamily A, polypeptide 13
chr6_+_31887761 1.87 ENST00000413154.1
complement component 2
chr17_-_34344991 1.85 ENST00000591423.1
chemokine (C-C motif) ligand 23
chr2_+_220363579 1.77 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GDP-mannose pyrophosphorylase A
chr2_+_44502630 1.76 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr1_-_197036364 1.70 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr14_+_21492331 1.70 ENST00000533984.1
ENST00000532213.2
AL161668.5
chr4_-_40477766 1.66 ENST00000507180.1
RNA binding motif protein 47
chr6_+_33172407 1.64 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chr11_+_2920951 1.62 ENST00000347936.2
solute carrier family 22, member 18
chr19_+_7660716 1.62 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr19_+_6464243 1.61 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr1_-_48227290 1.59 ENST00000594280.1
FLJ00388
chr12_-_7244469 1.57 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr11_-_72493574 1.56 ENST00000536290.1
StAR-related lipid transfer (START) domain containing 10
chr7_-_15601595 1.53 ENST00000342526.3
alkylglycerol monooxygenase
chr7_+_97840739 1.50 ENST00000609256.1
basic helix-loop-helix family, member a15
chr19_+_6464502 1.50 ENST00000308243.7
crumbs homolog 3 (Drosophila)
chr11_+_278365 1.49 ENST00000534750.1
NLR family, pyrin domain containing 6
chr1_+_158149737 1.44 ENST00000368171.3
CD1d molecule
chr15_+_58724184 1.44 ENST00000433326.2
lipase, hepatic
chr19_-_16045619 1.39 ENST00000402119.4
cytochrome P450, family 4, subfamily F, polypeptide 11
chr19_-_16045665 1.36 ENST00000248041.8
cytochrome P450, family 4, subfamily F, polypeptide 11
chr2_-_165698521 1.35 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
cordon-bleu WH2 repeat protein-like 1
chr8_-_144815966 1.34 ENST00000388913.3
family with sequence similarity 83, member H
chrX_+_38211777 1.30 ENST00000039007.4
ornithine carbamoyltransferase
chr1_+_53793885 1.28 ENST00000445039.2
RP4-784A16.5
chr12_+_121416340 1.26 ENST00000257555.6
ENST00000400024.2
HNF1 homeobox A
chr3_-_53878644 1.25 ENST00000481668.1
ENST00000467802.1
choline dehydrogenase
chr2_+_219646462 1.24 ENST00000258415.4
cytochrome P450, family 27, subfamily A, polypeptide 1
chr3_-_126236588 1.23 ENST00000383579.3
urocanate hydratase 1
chrX_+_66764375 1.19 ENST00000374690.3
androgen receptor
chr9_+_6716478 1.18 ENST00000452643.1
RP11-390F4.3
chrX_-_114253536 1.18 ENST00000371936.1
interleukin 13 receptor, alpha 2
chr2_-_165698662 1.17 ENST00000194871.6
ENST00000445474.2
cordon-bleu WH2 repeat protein-like 1
chr17_-_47786375 1.13 ENST00000511657.1
solute carrier family 35, member B1
chr12_-_7125770 1.12 ENST00000261407.4
lysophosphatidylcholine acyltransferase 3
chr3_-_126236605 1.11 ENST00000290868.2
urocanate hydratase 1
chr1_+_101185290 1.11 ENST00000370119.4
ENST00000347652.2
ENST00000294728.2
ENST00000370115.1
vascular cell adhesion molecule 1
chr11_+_18417813 1.10 ENST00000540430.1
ENST00000379412.5
lactate dehydrogenase A
chr8_-_128231299 1.08 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr1_+_176432298 1.07 ENST00000367661.3
ENST00000367662.3
pappalysin 2
chr13_+_113777105 1.04 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
coagulation factor X
chr19_+_49713991 1.04 ENST00000597316.1
transient receptor potential cation channel, subfamily M, member 4
chr12_+_121416437 1.03 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1 homeobox A
chr2_-_241836244 1.01 ENST00000454476.2
chromosome 2 open reading frame 54
chr19_-_58892389 1.01 ENST00000427624.2
ENST00000597582.1
zinc finger protein 837
chr7_+_65552756 1.00 ENST00000450043.1
AC068533.7
chr2_+_197577841 0.99 ENST00000409270.1
coiled-coil domain containing 150
chr2_-_241836298 0.99 ENST00000414499.1
chromosome 2 open reading frame 54
chr5_-_42812143 0.97 ENST00000514985.1
selenoprotein P, plasma, 1
chr4_-_109683691 0.96 ENST00000512320.1
ENST00000510723.1
ethanolamine-phosphate phospho-lyase
chr12_+_132413765 0.95 ENST00000376649.3
ENST00000322060.5
pseudouridylate synthase 1
chr5_-_95158644 0.94 ENST00000237858.6
glutaredoxin (thioltransferase)
chr16_+_2076869 0.93 ENST00000424542.2
ENST00000432365.2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr21_-_45682099 0.91 ENST00000270172.3
ENST00000418993.1
DNA (cytosine-5-)-methyltransferase 3-like
chr2_-_70780770 0.90 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
transforming growth factor, alpha
chr12_+_132413739 0.90 ENST00000443358.2
pseudouridylate synthase 1
chr16_-_31439735 0.90 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr2_-_198364552 0.89 ENST00000439605.1
ENST00000418022.1
heat shock 60kDa protein 1 (chaperonin)
chr4_+_159593418 0.89 ENST00000507475.1
ENST00000307738.5
electron-transferring-flavoprotein dehydrogenase
chr6_+_143381594 0.89 ENST00000367601.4
androgen-induced 1
chr10_+_114133773 0.88 ENST00000354655.4
acyl-CoA synthetase long-chain family member 5
chr2_+_219283815 0.88 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
villin 1
chr17_+_4853442 0.88 ENST00000522301.1
enolase 3 (beta, muscle)
chr11_+_63137251 0.87 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr7_+_192969 0.87 ENST00000313766.5
family with sequence similarity 20, member C
chr5_-_42811986 0.87 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chrX_-_128977364 0.86 ENST00000371064.3
zinc finger, DHHC-type containing 9
chr16_+_83932684 0.84 ENST00000262430.4
malonyl-CoA decarboxylase
chr16_+_21244986 0.83 ENST00000311620.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr12_-_56727676 0.82 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr14_-_23284703 0.81 ENST00000555911.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_27005686 0.81 ENST00000380055.5
leucine rich repeat containing 19
chr2_+_138721850 0.81 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr16_-_30997533 0.80 ENST00000602217.1
Uncharacterized protein
chr2_-_198364581 0.80 ENST00000428204.1
heat shock 60kDa protein 1 (chaperonin)
chr2_+_198365095 0.77 ENST00000409468.1
heat shock 10kDa protein 1
chr14_-_23285069 0.77 ENST00000554758.1
ENST00000397528.4
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_56727487 0.77 ENST00000548043.1
ENST00000425394.2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr14_-_23285011 0.74 ENST00000397532.3
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr11_-_31014214 0.74 ENST00000406071.2
ENST00000339794.5
doublecortin domain containing 1
chr12_-_56367101 0.73 ENST00000549233.2
premelanosome protein
chr1_+_33207381 0.72 ENST00000401073.2
KIAA1522
chr17_-_2614927 0.71 ENST00000435359.1
clustered mitochondria (cluA/CLU1) homolog
chr14_+_24590560 0.71 ENST00000558325.1
RP11-468E2.6
chr6_+_43737939 0.70 ENST00000372067.3
vascular endothelial growth factor A
chr13_+_100741269 0.70 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
propionyl CoA carboxylase, alpha polypeptide
chr6_+_7108210 0.68 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr5_+_118965244 0.68 ENST00000515256.1
ENST00000509264.1
family with sequence similarity 170, member A
chr19_+_10362882 0.67 ENST00000393733.2
ENST00000588502.1
mitochondrial ribosomal protein L4
chr1_-_43751276 0.67 ENST00000423420.1
chromosome 1 open reading frame 210
chr7_-_100844193 0.66 ENST00000440203.2
ENST00000379423.3
ENST00000223114.4
monoacylglycerol O-acyltransferase 3
chr19_-_38806390 0.66 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr13_+_76413852 0.65 ENST00000533809.2
LIM domain 7
chr19_-_38806540 0.64 ENST00000592694.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr17_-_7307358 0.64 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr4_-_141075330 0.63 ENST00000509479.2
mastermind-like 3 (Drosophila)
chr17_-_80017856 0.63 ENST00000577574.1
dihydrouridine synthase 1-like (S. cerevisiae)
chr12_+_132413798 0.62 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
pseudouridylate synthase 1
chr8_-_70016408 0.61 ENST00000518540.1
RP11-600K15.1
chr12_+_6494285 0.61 ENST00000541102.1
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr11_-_124543725 0.60 ENST00000545756.1
ENST00000263593.3
sialic acid acetylesterase
chr11_-_26743546 0.60 ENST00000280467.6
ENST00000396005.3
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr19_-_39303576 0.59 ENST00000594209.1
lectin, galactoside-binding, soluble, 4
chr7_+_107301065 0.58 ENST00000265715.3
solute carrier family 26 (anion exchanger), member 4
chr11_+_12108410 0.58 ENST00000527997.1
RP13-631K18.5
chr2_+_44502597 0.57 ENST00000260649.6
ENST00000409387.1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr1_+_28696111 0.57 ENST00000373839.3
phosphatase and actin regulator 4
chr6_+_30131318 0.55 ENST00000376688.1
tripartite motif containing 15
chr3_+_113465866 0.55 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr8_-_80942467 0.54 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
mitochondrial ribosomal protein S28
chr14_-_23284675 0.54 ENST00000555959.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_-_73460334 0.54 ENST00000258083.2
protease-associated domain containing 1
chr15_+_90728145 0.53 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_-_171178157 0.53 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TRAF2 and NCK interacting kinase
chr3_-_139195350 0.53 ENST00000232217.2
retinol binding protein 2, cellular
chr9_-_95896550 0.52 ENST00000375446.4
ninjurin 1
chr9_-_98079154 0.51 ENST00000433829.1
Fanconi anemia, complementation group C
chr19_-_38806560 0.51 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chr10_+_81107271 0.51 ENST00000448165.1
peptidylprolyl isomerase F
chr11_-_1776176 0.51 ENST00000429746.1
cathepsin D
chr9_-_127358087 0.51 ENST00000475178.1
nuclear receptor subfamily 6, group A, member 1
chr19_+_10197463 0.51 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr2_-_85581701 0.49 ENST00000295802.4
retinol saturase (all-trans-retinol 13,14-reductase)
chr8_-_37594944 0.49 ENST00000330539.1
Uncharacterized protein
chr20_-_62601218 0.49 ENST00000369888.1
zinc finger protein 512B
chr2_+_198365122 0.48 ENST00000604458.1
HSPE1-MOB4 readthrough
chr22_-_47882857 0.48 ENST00000405369.3
Novel protein; Uncharacterized protein
chr6_+_32146131 0.48 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chr7_-_105926058 0.47 ENST00000417537.1
nicotinamide phosphoribosyltransferase
chr17_-_2615031 0.46 ENST00000576885.1
ENST00000574426.2
clustered mitochondria (cluA/CLU1) homolog
chr3_-_141747459 0.46 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr16_+_4475806 0.46 ENST00000262375.6
ENST00000355296.4
ENST00000431375.2
ENST00000574895.1
DnaJ (Hsp40) homolog, subfamily A, member 3
chr10_-_74114714 0.46 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DnaJ (Hsp40) homolog, subfamily B, member 12
chr22_-_24641027 0.46 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr2_-_85581623 0.45 ENST00000449375.1
ENST00000409984.2
ENST00000457495.2
ENST00000263854.6
retinol saturase (all-trans-retinol 13,14-reductase)

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
2.0 8.0 GO:0035565 regulation of pronephros size(GO:0035565)
1.6 4.7 GO:0006114 glycerol biosynthetic process(GO:0006114)
1.4 9.9 GO:0002933 lipid hydroxylation(GO:0002933)
1.2 8.5 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
1.2 3.6 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.9 2.8 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.8 2.5 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.8 4.9 GO:0032571 response to vitamin K(GO:0032571)
0.8 5.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.8 2.3 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.7 4.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.7 2.7 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.7 2.0 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.7 4.6 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.6 6.7 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.6 1.7 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.5 5.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.5 4.0 GO:0009441 glycolate metabolic process(GO:0009441)
0.5 11.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.5 5.2 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.4 6.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.3 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.4 2.0 GO:0019303 D-ribose catabolic process(GO:0019303)
0.4 1.2 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.4 1.5 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.4 1.1 GO:0060349 bone morphogenesis(GO:0060349)
0.3 2.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 2.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 1.3 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 2.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.3 2.6 GO:0034378 chylomicron assembly(GO:0034378)
0.3 0.9 GO:0097187 dentinogenesis(GO:0097187)
0.3 7.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.3 7.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.1 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.3 3.1 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.3 1.0 GO:1904199 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.2 0.7 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.8 GO:1904106 protein localization to microvillus(GO:1904106)
0.2 1.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 1.6 GO:0046618 drug export(GO:0046618)
0.2 1.6 GO:0032782 bile acid secretion(GO:0032782)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.9 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.5 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 2.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 1.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.2 2.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 1.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 1.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 4.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 2.7 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1 0.8 GO:0015692 lead ion transport(GO:0015692)
0.1 1.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.8 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 1.2 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.1 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 2.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.9 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 1.7 GO:0070255 regulation of mucus secretion(GO:0070255)
0.1 5.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 3.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.9 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 1.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 3.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 5.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 2.2 GO:0006525 arginine metabolic process(GO:0006525)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 3.5 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.9 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 2.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 1.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.8 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.1 1.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 1.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 6.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.7 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.9 GO:0072189 ureter development(GO:0072189)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.9 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 1.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.0 0.5 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 3.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 2.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.5 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 1.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 2.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.9 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.1 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.9 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.7 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.7 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 1.0 GO:0007602 phototransduction(GO:0007602)
0.0 0.9 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.5 6.0 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 12.4 GO:0042627 chylomicron(GO:0042627)
0.4 1.6 GO:0031251 PAN complex(GO:0031251)
0.4 1.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 3.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 1.6 GO:0005915 zonula adherens(GO:0005915)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.5 GO:0031415 NatA complex(GO:0031415)
0.1 2.7 GO:0000145 exocyst(GO:0000145)
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.1 7.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 4.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.6 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 2.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 8.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.6 GO:0031252 cell leading edge(GO:0031252)
0.0 1.0 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 13.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 39.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.9 GO:0031526 brush border membrane(GO:0031526)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 3.7 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 7.2 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 3.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0001669 acrosomal vesicle(GO:0001669) sperm part(GO:0097223)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.6 4.7 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.3 4.0 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
1.1 8.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.8 4.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.8 5.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.8 2.5 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.8 8.2 GO:0005497 androgen binding(GO:0005497)
0.8 2.3 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.8 2.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.7 2.9 GO:0001855 complement component C4b binding(GO:0001855)
0.7 15.3 GO:0070330 aromatase activity(GO:0070330)
0.7 2.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.6 2.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.6 3.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 1.6 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.5 3.7 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 7.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.4 1.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.3 8.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 2.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 2.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 0.9 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.3 1.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.3 1.7 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.3 1.6 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 1.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 2.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 2.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 2.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.2 1.3 GO:1990254 keratin filament binding(GO:1990254)
0.2 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.2 2.5 GO:0031996 thioesterase binding(GO:0031996)
0.2 0.5 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.2 1.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.4 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 3.1 GO:0005537 mannose binding(GO:0005537)
0.1 2.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 7.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.5 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 2.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 2.8 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.1 1.5 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 12.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 2.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 3.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 1.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.7 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.1 1.3 GO:0042301 phosphate ion binding(GO:0042301)
0.1 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 1.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 4.0 GO:0005507 copper ion binding(GO:0005507)
0.0 2.0 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 1.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 2.3 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 4.5 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 3.3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.3 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 22.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 8.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 1.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 8.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.2 ST ADRENERGIC Adrenergic Pathway
0.0 13.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 2.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 21.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.7 15.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 17.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.6 8.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 6.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 4.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 4.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 7.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 9.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 3.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 7.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 5.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 5.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 2.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 5.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 5.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint