Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for NR5A2
Z-value: 2.05
Motif logo
Transcription factors associated with NR5A2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR5A2 | hg19_v2_chr1_+_199996859_199997011 | -0.48 | 5.6e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of NR5A2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.0 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.2 | 7.8 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.1 | 6.7 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 1.1 | 6.6 | GO:0071422 | succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) |
| 1.6 | 6.2 | GO:1903060 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 0.1 | 6.1 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 5.4 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 1.0 | 5.0 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697) |
| 0.7 | 4.8 | GO:0008218 | bioluminescence(GO:0008218) |
| 1.1 | 4.3 | GO:0003330 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 9.5 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.1 | 6.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.5 | 5.7 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.1 | 5.4 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.6 | 5.0 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.3 | 4.8 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 4.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.7 | 4.2 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.1 | 4.1 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) respiratory chain complex(GO:0098803) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 7.8 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.0 | 6.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 1.1 | 6.6 | GO:0015141 | succinate transmembrane transporter activity(GO:0015141) |
| 0.2 | 6.3 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 5.9 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.2 | 5.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.7 | 5.0 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.2 | 5.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 4.9 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.7 | 4.7 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 6.0 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 5.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.2 | 3.7 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 2.7 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 2.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 2.1 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 2.0 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.8 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 1.8 | PID EPHB FWD PATHWAY | EPHB forward signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 9.5 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.0 | 7.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 6.9 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.3 | 5.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.2 | 5.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.2 | 4.9 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.1 | 4.9 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 4.9 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.1 | 4.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |