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Illumina Body Map 2: averaged replicates

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Results for NR6A1

Z-value: 1.57

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
ENSG00000148200.12 NR6A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v2_chr9_-_127358087_127358170-0.232.0e-01Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_106539557 3.37 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr14_-_96180435 3.22 ENST00000556450.1
ENST00000555202.1
ENST00000554012.1
ENST00000402399.1
TCL1A
T-cell leukemia/lymphoma 1A
chr19_-_7797045 2.98 ENST00000328853.5
CLEC4G
C-type lectin domain family 4, member G
chr15_-_20170354 2.92 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr9_-_137809718 2.85 ENST00000371806.3
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr14_+_22670455 2.81 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr14_-_106733624 2.78 ENST00000390610.2
IGHV1-24
immunoglobulin heavy variable 1-24
chr15_-_22448819 2.76 ENST00000604066.1
IGHV1OR15-1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr14_-_106471723 2.74 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr14_-_106642049 2.69 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr19_-_10446449 2.64 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr5_+_156607829 2.59 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr14_-_106453155 2.54 ENST00000390594.2
IGHV1-2
immunoglobulin heavy variable 1-2
chr12_+_9980069 2.46 ENST00000354855.3
ENST00000324214.4
ENST00000279544.3
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chrX_-_70329118 2.29 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr7_+_142012967 2.27 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chr17_+_45810594 2.20 ENST00000177694.1
TBX21
T-box 21
chr1_-_183538319 2.18 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr1_+_159770292 2.15 ENST00000536257.1
ENST00000321935.6
FCRL6
Fc receptor-like 6
chr19_+_42381173 2.10 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr1_-_153517473 2.07 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr5_-_138725560 2.07 ENST00000412103.2
ENST00000457570.2
MZB1
marginal zone B and B1 cell-specific protein
chr22_+_23229960 2.04 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr2_-_60780607 2.02 ENST00000537768.1
ENST00000335712.6
ENST00000356842.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr5_-_138725594 2.00 ENST00000302125.8
MZB1
marginal zone B and B1 cell-specific protein
chr21_+_10862622 1.96 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_-_60780536 1.96 ENST00000538214.1
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr1_-_160616804 1.95 ENST00000538290.1
SLAMF1
signaling lymphocytic activation molecule family member 1
chr20_+_43803517 1.92 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr19_+_42381337 1.91 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr2_-_60780546 1.82 ENST00000358510.4
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr12_+_9980113 1.81 ENST00000537723.1
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr7_-_142232071 1.69 ENST00000390364.3
TRBV10-1
T cell receptor beta variable 10-1(gene/pseudogene)
chr14_-_107095662 1.69 ENST00000390630.2
IGHV4-61
immunoglobulin heavy variable 4-61
chr19_+_42082506 1.68 ENST00000187608.9
ENST00000401445.2
CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr2_-_60780702 1.66 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chrY_-_21906623 1.65 ENST00000382806.2
KDM5D
lysine (K)-specific demethylase 5D
chr12_+_60058458 1.63 ENST00000548610.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr14_-_106963409 1.58 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr3_+_114012819 1.50 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr7_+_142045246 1.46 ENST00000390392.3
TRBV4-2
T cell receptor beta variable 4-2
chrX_-_118827333 1.43 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr6_+_106534192 1.42 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr22_+_42148515 1.39 ENST00000540880.1
MEI1
meiosis inhibitor 1
chr16_+_31366536 1.36 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr22_-_24181174 1.34 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3
derlin 3
chrX_+_48644962 1.33 ENST00000376670.3
ENST00000376665.3
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr7_+_80253387 1.32 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chrX_+_135730297 1.29 ENST00000370629.2
CD40LG
CD40 ligand
chr10_-_14613968 1.29 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr7_+_142448053 1.29 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr14_+_22978168 1.29 ENST00000390505.1
TRAJ32
T cell receptor alpha joining 32
chr2_+_28853443 1.27 ENST00000436775.1
PLB1
phospholipase B1
chr11_-_5271122 1.27 ENST00000330597.3
HBG1
hemoglobin, gamma A
chrX_-_118827113 1.24 ENST00000394617.2
SEPT6
septin 6
chr7_-_87936195 1.22 ENST00000414498.1
ENST00000301959.5
ENST00000380079.4
STEAP4
STEAP family member 4
chr1_-_207095212 1.21 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr17_-_18945798 1.21 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr21_-_46330545 1.21 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_41699135 1.21 ENST00000542619.1
ENST00000600561.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr11_-_64511575 1.21 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr7_-_36634181 1.19 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr12_+_2079939 1.14 ENST00000543114.1
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr12_+_54384370 1.14 ENST00000504315.1
HOXC6
homeobox C6
chr10_-_14614122 1.09 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr17_+_48712206 1.07 ENST00000427699.1
ENST00000285238.8
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr17_-_39093672 1.07 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr2_+_69002052 1.04 ENST00000497079.1
ARHGAP25
Rho GTPase activating protein 25
chr11_+_118754475 1.03 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr10_-_14614095 1.03 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr15_+_76629064 1.02 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr12_+_54410664 1.01 ENST00000303406.4
HOXC4
homeobox C4
chr2_+_69001913 1.01 ENST00000409030.3
ENST00000409220.1
ARHGAP25
Rho GTPase activating protein 25
chr19_-_10679644 1.01 ENST00000393599.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr2_-_175547571 1.00 ENST00000409415.3
ENST00000359761.3
ENST00000272746.5
WIPF1
WAS/WASL interacting protein family, member 1
chr11_-_64512273 1.00 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_777739 0.99 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_+_81772633 0.98 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
RP11-960L18.1
PLCG2
RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_111415757 0.98 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr17_+_7338737 0.97 ENST00000323206.1
ENST00000396568.1
TMEM102
transmembrane protein 102
chr12_-_54691668 0.97 ENST00000553198.1
NFE2
nuclear factor, erythroid 2
chr6_-_32339649 0.94 ENST00000527965.1
ENST00000532023.1
ENST00000447241.2
ENST00000375007.4
ENST00000534588.1
C6orf10
chromosome 6 open reading frame 10
chr16_+_31366455 0.94 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr16_-_3306587 0.92 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr6_-_32339671 0.90 ENST00000442822.2
ENST00000375015.4
ENST00000533191.1
C6orf10
chromosome 6 open reading frame 10
chr17_-_56494713 0.89 ENST00000407977.2
RNF43
ring finger protein 43
chr16_-_18801643 0.89 ENST00000322989.4
ENST00000563390.1
RPS15A
ribosomal protein S15a
chr19_+_41698927 0.89 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr18_+_23713808 0.87 ENST00000415576.2
ENST00000343848.6
ENST00000308268.6
PSMA8
proteasome (prosome, macropain) subunit, alpha type, 8
chr16_-_18801582 0.87 ENST00000565420.1
RPS15A
ribosomal protein S15a
chr7_+_142985308 0.86 ENST00000310447.5
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr13_-_114898016 0.86 ENST00000542651.1
ENST00000334062.7
RASA3
RAS p21 protein activator 3
chr10_+_11207438 0.85 ENST00000609692.1
ENST00000354897.3
CELF2
CUGBP, Elav-like family member 2
chr19_-_10679697 0.84 ENST00000335766.2
CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_-_203198790 0.82 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr8_-_59412717 0.81 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr14_+_38033252 0.81 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr14_+_22968672 0.80 ENST00000390497.1
TRAJ40
T cell receptor alpha joining 40
chr12_-_53594227 0.79 ENST00000550743.2
ITGB7
integrin, beta 7
chr10_-_14574705 0.79 ENST00000489100.1
FAM107B
family with sequence similarity 107, member B
chr1_+_29213584 0.77 ENST00000343067.4
ENST00000356093.2
ENST00000398863.2
ENST00000373800.3
ENST00000349460.4
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_184943610 0.77 ENST00000367511.3
FAM129A
family with sequence similarity 129, member A
chr10_-_14614311 0.76 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr2_+_68592305 0.75 ENST00000234313.7
PLEK
pleckstrin
chr12_-_2027639 0.75 ENST00000586184.1
ENST00000587995.1
ENST00000585732.1
CACNA2D4
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chrY_+_16636354 0.74 ENST00000339174.5
NLGN4Y
neuroligin 4, Y-linked
chr7_-_87104963 0.72 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ABCB4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr6_+_31674639 0.72 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr3_+_32993065 0.72 ENST00000330953.5
CCR4
chemokine (C-C motif) receptor 4
chr19_-_4540486 0.70 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr11_+_111957497 0.70 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr6_+_146864829 0.69 ENST00000367495.3
RAB32
RAB32, member RAS oncogene family
chr10_+_11207485 0.68 ENST00000537122.1
CELF2
CUGBP, Elav-like family member 2
chr12_-_7261772 0.68 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr16_+_30212378 0.67 ENST00000569485.1
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr7_-_55640176 0.67 ENST00000285279.5
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr3_-_46249878 0.66 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1
chr19_+_52255261 0.66 ENST00000600258.1
FPR2
formyl peptide receptor 2
chr5_-_180668605 0.65 ENST00000504128.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr16_+_776936 0.65 ENST00000549114.1
ENST00000341413.4
ENST00000562187.1
ENST00000564537.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr7_+_142985467 0.65 ENST00000392925.2
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr19_-_43383850 0.64 ENST00000436291.2
ENST00000595124.1
ENST00000244296.2
PSG1
pregnancy specific beta-1-glycoprotein 1
chr8_-_141645645 0.64 ENST00000519980.1
ENST00000220592.5
AGO2
argonaute RISC catalytic component 2
chr17_+_7452189 0.64 ENST00000293825.6
TNFSF12
tumor necrosis factor (ligand) superfamily, member 12
chr7_+_150521691 0.64 ENST00000493429.1
AOC1
amine oxidase, copper containing 1
chr6_+_5085572 0.63 ENST00000405617.2
PPP1R3G
protein phosphatase 1, regulatory subunit 3G
chr12_-_109219937 0.62 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr14_-_47120956 0.62 ENST00000298283.3
RPL10L
ribosomal protein L10-like
chr16_-_3422283 0.62 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr16_-_2836606 0.61 ENST00000571674.1
ENST00000293851.5
ENST00000576886.1
PRSS33
protease, serine, 33
chr20_+_3052264 0.60 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chr5_-_176836577 0.60 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr17_+_74075263 0.60 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr20_+_31749574 0.60 ENST00000253362.2
BPIFA2
BPI fold containing family A, member 2
chr2_+_33701707 0.59 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_207024306 0.58 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr8_+_103563792 0.57 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr16_-_12897642 0.57 ENST00000433677.2
ENST00000261660.4
ENST00000381774.4
CPPED1
calcineurin-like phosphoesterase domain containing 1
chr17_+_76210267 0.56 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr9_-_39239171 0.56 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr7_-_141957847 0.56 ENST00000552471.1
ENST00000547058.2
PRSS58
protease, serine, 58
chr11_-_78052923 0.56 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr3_-_72496035 0.55 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr10_-_76995675 0.55 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr11_+_65407331 0.55 ENST00000527525.1
SIPA1
signal-induced proliferation-associated 1
chr9_-_130679257 0.55 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr17_+_12453278 0.55 ENST00000577679.1
LINC00670
long intergenic non-protein coding RNA 670
chr11_-_111957451 0.54 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr19_+_49990811 0.54 ENST00000391857.4
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr2_-_287299 0.53 ENST00000405290.1
FAM150B
family with sequence similarity 150, member B
chr21_+_43639211 0.53 ENST00000450121.1
ENST00000398449.3
ENST00000361802.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr8_+_144640499 0.52 ENST00000525721.1
ENST00000534018.1
GSDMD
gasdermin D
chr12_-_48214345 0.52 ENST00000433685.1
ENST00000447463.1
ENST00000427332.2
HDAC7
histone deacetylase 7
chr1_-_16532985 0.51 ENST00000441785.1
ENST00000449495.1
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr6_-_33548006 0.51 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr2_+_201994208 0.50 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_+_55417499 0.50 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr16_-_48644061 0.50 ENST00000262384.3
N4BP1
NEDD4 binding protein 1
chr6_+_41303372 0.50 ENST00000373083.4
ENST00000373089.5
ENST00000373086.3
NCR2
natural cytotoxicity triggering receptor 2
chr10_-_50396425 0.48 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr3_-_52312337 0.48 ENST00000469000.1
WDR82
WD repeat domain 82
chr17_-_46682321 0.48 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr18_+_61557781 0.48 ENST00000443281.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr16_-_11723066 0.48 ENST00000576036.1
LITAF
lipopolysaccharide-induced TNF factor
chr16_+_777118 0.48 ENST00000562141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr16_-_30122717 0.47 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_+_151739131 0.47 ENST00000400999.1
OAZ3
ornithine decarboxylase antizyme 3
chr3_+_151986709 0.47 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr8_+_144640477 0.46 ENST00000262580.4
GSDMD
gasdermin D
chr5_+_3596168 0.46 ENST00000302006.3
IRX1
iroquois homeobox 1
chr10_+_114135004 0.45 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_49956426 0.45 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr2_+_134877740 0.44 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chrX_+_142967173 0.44 ENST00000370494.1
UBE2NL
ubiquitin-conjugating enzyme E2N-like
chr2_-_69180083 0.44 ENST00000328895.4
GKN2
gastrokine 2
chr21_+_34697209 0.44 ENST00000270139.3
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr3_-_129279894 0.44 ENST00000506979.1
PLXND1
plexin D1
chr1_-_109203648 0.44 ENST00000370031.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr16_+_777246 0.43 ENST00000561546.1
ENST00000564545.1
ENST00000389703.3
ENST00000567414.1
ENST00000568141.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr20_-_35402123 0.43 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1
DSN1, MIS12 kinetochore complex component
chr7_+_142919130 0.43 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr6_+_144980954 0.43 ENST00000367525.3
UTRN
utrophin
chr6_+_25652501 0.43 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chr19_-_344786 0.43 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr14_-_106370569 0.42 ENST00000390584.1
IGHD3-9
immunoglobulin heavy diversity 3-9
chr10_+_114710516 0.42 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_+_22782867 0.42 ENST00000390467.3
TRAV40
T cell receptor alpha variable 40
chr8_+_145086574 0.42 ENST00000377470.3
ENST00000447830.2
SPATC1
spermatogenesis and centriole associated 1
chr6_+_25652432 0.42 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chr1_-_29508499 0.42 ENST00000373795.4
SRSF4
serine/arginine-rich splicing factor 4
chr4_-_78740769 0.41 ENST00000512485.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr11_+_3876859 0.41 ENST00000300737.4
STIM1
stromal interaction molecule 1
chr20_-_44259893 0.41 ENST00000326000.1
WFDC9
WAP four-disulfide core domain 9
chr6_-_33547975 0.41 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr11_-_119599794 0.40 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr1_+_92417716 0.40 ENST00000402388.1
BRDT
bromodomain, testis-specific
chr16_-_75498308 0.39 ENST00000569540.1
TMEM170A
transmembrane protein 170A
chr7_-_14026063 0.39 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr22_+_30163340 0.39 ENST00000330029.6
ENST00000401406.3
UQCR10
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_+_41699103 0.39 ENST00000597754.1
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:1904799 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
1.0 2.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.9 2.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.7 4.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.5 1.4 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.3 1.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.3 0.9 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 2.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.3 1.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.3 20.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.0 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.2 1.0 GO:0002316 follicular B cell differentiation(GO:0002316)
0.2 0.7 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.2 0.6 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 1.6 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.2 0.6 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 1.5 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.2 3.2 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.2 2.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 0.5 GO:0086044 pulmonary valve formation(GO:0003193) atrial ventricular junction remodeling(GO:0003294) foramen ovale closure(GO:0035922) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.2 0.9 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 1.9 GO:0048102 autophagic cell death(GO:0048102)
0.2 1.2 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.7 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 1.7 GO:0034720 T cell antigen processing and presentation(GO:0002457) histone H3-K4 demethylation(GO:0034720)
0.1 2.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.5 GO:0055099 detection of endogenous stimulus(GO:0009726) response to high density lipoprotein particle(GO:0055099)
0.1 0.4 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 1.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.6 GO:0071504 cellular response to heparin(GO:0071504)
0.1 2.7 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.3 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 2.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.8 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 0.6 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.0 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 1.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.3 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.2 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.1 2.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 1.5 GO:0045141 meiotic telomere clustering(GO:0045141)
0.1 1.9 GO:0007620 copulation(GO:0007620)
0.1 0.3 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.5 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 1.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 1.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 1.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.1 2.1 GO:0045730 respiratory burst(GO:0045730)
0.1 0.7 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 1.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 1.0 GO:0048535 lymph node development(GO:0048535)
0.0 0.4 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.5 GO:1903943 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.6 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 1.0 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 4.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.7 GO:0002507 tolerance induction(GO:0002507)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 2.0 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 2.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 3.5 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 2.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.9 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 1.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.7 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0035573 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.6 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 2.6 GO:0000910 cytokinesis(GO:0000910)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.6 4.0 GO:0019815 B cell receptor complex(GO:0019815)
0.4 19.2 GO:0019814 immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.3 2.8 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 1.9 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 2.2 GO:0032010 phagolysosome(GO:0032010)
0.2 0.7 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 0.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 1.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 3.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 1.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.3 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.6 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.0 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 2.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560) cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.6 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 1.8 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 7.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 1.7 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 3.1 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.0 GO:0001726 ruffle(GO:0001726)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.4 1.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.4 1.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.4 2.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 4.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.3 1.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 19.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.3 0.8 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.3 1.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.2 0.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 0.9 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 0.5 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.2 0.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 1.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.2 2.8 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.6 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.4 GO:0019961 interferon binding(GO:0019961)
0.1 1.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.7 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 2.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.7 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 3.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.7 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.3 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 3.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 2.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 1.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 3.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 2.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 1.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.2 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.3 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 1.0 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.8 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 1.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 7.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 3.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.8 GO:0048038 quinone binding(GO:0048038)
0.0 1.0 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.4 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 4.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 2.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 4.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 2.2 PID IL27 PATHWAY IL27-mediated signaling events
0.1 5.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 5.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.9 PID P73PATHWAY p73 transcription factor network
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 5.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 5.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 8.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 2.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 2.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 2.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.2 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs