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Illumina Body Map 2: averaged replicates

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Results for ONECUT1

Z-value: 3.34

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Transcription factors associated with ONECUT1

Gene Symbol Gene ID Gene Info
ENSG00000169856.7 ONECUT1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ONECUT1hg19_v2_chr15_-_53082178_530822090.451.1e-02Click!

Activity profile of ONECUT1 motif

Sorted Z-values of ONECUT1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ONECUT1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_57320437 18.62 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr1_-_159684371 17.73 ENST00000255030.5
ENST00000437342.1
ENST00000368112.1
ENST00000368111.1
ENST00000368110.1
ENST00000343919.2
CRP
C-reactive protein, pentraxin-related
chr12_+_111471828 17.22 ENST00000261726.6
CUX2
cut-like homeobox 2
chr1_+_159557607 17.11 ENST00000255040.2
APCS
amyloid P component, serum
chr13_-_46679144 15.96 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr9_-_116840728 15.41 ENST00000265132.3
AMBP
alpha-1-microglobulin/bikunin precursor
chr3_-_170744498 15.00 ENST00000382808.4
ENST00000314251.3
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr13_-_46679185 14.52 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr17_-_26697304 13.88 ENST00000536498.1
VTN
vitronectin
chr3_+_186383741 13.70 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr3_+_52811596 13.33 ENST00000542827.1
ENST00000273283.2
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chrX_+_70435044 10.93 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1
gap junction protein, beta 1, 32kDa
chr2_+_234959323 9.91 ENST00000373368.1
ENST00000168148.3
SPP2
secreted phosphoprotein 2, 24kDa
chr19_+_45449301 9.59 ENST00000591597.1
APOC2
apolipoprotein C-II
chr19_+_45449228 9.53 ENST00000252490.4
APOC2
apolipoprotein C-II
chr15_-_53097139 9.05 ENST00000560818.1
RP11-209K10.2
RP11-209K10.2
chr17_-_64225508 8.95 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_+_45449266 8.56 ENST00000592257.1
APOC2
apolipoprotein C-II
chr10_+_115312766 8.33 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr16_+_27214802 8.29 ENST00000380948.2
ENST00000286096.4
KDM8
lysine (K)-specific demethylase 8
chr1_-_9563433 8.28 ENST00000441033.1
RP13-392I16.1
RP13-392I16.1
chr1_+_207262540 8.23 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr17_+_41052808 8.18 ENST00000592383.1
ENST00000253801.2
ENST00000585489.1
G6PC
glucose-6-phosphatase, catalytic subunit
chr1_+_207262578 8.14 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr12_+_56623827 8.09 ENST00000424625.1
ENST00000419753.1
ENST00000454355.2
ENST00000417965.1
ENST00000436633.1
SLC39A5
solute carrier family 39 (zinc transporter), member 5
chr5_-_176836577 7.94 ENST00000253496.3
F12
coagulation factor XII (Hageman factor)
chr2_+_234959376 7.75 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr19_-_58864848 7.38 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chrX_+_122318006 7.29 ENST00000371266.1
ENST00000264357.5
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr12_+_56624436 7.06 ENST00000266980.4
ENST00000437277.1
SLC39A5
solute carrier family 39 (zinc transporter), member 5
chr1_+_207262627 6.99 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr12_-_53297432 6.83 ENST00000546900.1
KRT8
keratin 8
chr10_+_115312825 6.19 ENST00000537906.1
ENST00000541666.1
HABP2
hyaluronan binding protein 2
chr11_+_63057412 6.07 ENST00000544661.1
SLC22A10
solute carrier family 22, member 10
chr2_+_234600253 6.07 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr18_-_68004529 6.06 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr20_-_22566089 6.02 ENST00000377115.4
FOXA2
forkhead box A2
chr1_-_197036364 5.62 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr1_-_151804314 5.49 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr4_+_187187098 5.26 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr20_-_22559211 5.20 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr18_+_68002675 4.86 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr18_+_47087055 4.79 ENST00000577628.1
LIPG
lipase, endothelial
chr1_-_151804222 4.78 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr13_-_114018400 4.72 ENST00000375430.4
ENST00000375431.4
GRTP1
growth hormone regulated TBC protein 1
chrX_+_122318113 4.70 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr18_+_56113488 4.66 ENST00000590797.1
RP11-1151B14.3
RP11-1151B14.3
chr2_+_223536428 4.60 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr22_-_37505588 4.45 ENST00000406856.1
TMPRSS6
transmembrane protease, serine 6
chr3_-_164914640 4.32 ENST00000241274.3
SLITRK3
SLIT and NTRK-like family, member 3
chr22_-_37505449 4.27 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr2_+_108863651 4.19 ENST00000329106.2
ENST00000376700.1
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr5_+_42756903 4.16 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr20_+_42984330 4.04 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr10_-_94003003 3.91 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr14_+_74083548 3.82 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr10_-_5227096 3.81 ENST00000488756.1
ENST00000334314.3
AKR1CL1
aldo-keto reductase family 1, member C-like 1
chr12_-_21487829 3.73 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr7_-_96132835 3.65 ENST00000356686.1
C7orf76
chromosome 7 open reading frame 76
chr18_+_47087390 3.45 ENST00000583083.1
LIPG
lipase, endothelial
chr2_-_85788652 3.37 ENST00000430215.3
GGCX
gamma-glutamyl carboxylase
chr3_-_24207039 3.25 ENST00000280696.5
THRB
thyroid hormone receptor, beta
chr17_-_17485731 3.22 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr2_+_20650796 3.15 ENST00000448241.1
AC023137.2
AC023137.2
chr17_+_53342311 3.15 ENST00000226067.5
HLF
hepatic leukemia factor
chrX_-_131623982 3.14 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr3_+_159557637 3.12 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr1_+_207262881 3.10 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr4_-_141348999 3.06 ENST00000325617.5
CLGN
calmegin
chr11_+_19799327 3.05 ENST00000540292.1
NAV2
neuron navigator 2
chr7_-_121784285 2.99 ENST00000417368.2
AASS
aminoadipate-semialdehyde synthase
chr18_-_24765248 2.94 ENST00000580774.1
ENST00000284224.8
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_-_177939348 2.89 ENST00000464631.2
SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_-_8075693 2.86 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr4_-_175443484 2.83 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr4_+_159727222 2.77 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr2_-_200715834 2.66 ENST00000420128.1
ENST00000416668.1
FTCDNL1
formiminotransferase cyclodeaminase N-terminal like
chr19_-_48016023 2.64 ENST00000598615.1
ENST00000597118.1
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr3_+_142315294 2.60 ENST00000464320.1
PLS1
plastin 1
chr4_+_159727272 2.52 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr2_-_197457335 2.50 ENST00000260983.3
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_+_241375069 2.48 ENST00000264039.2
GPC1
glypican 1
chr10_+_69869237 2.47 ENST00000373675.3
MYPN
myopalladin
chr12_+_21679220 2.46 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr11_+_57365150 2.44 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr14_+_74058410 2.43 ENST00000326303.4
ACOT4
acyl-CoA thioesterase 4
chr13_+_30002846 2.41 ENST00000542829.1
MTUS2
microtubule associated tumor suppressor candidate 2
chr1_-_154167124 2.39 ENST00000515609.1
TPM3
tropomyosin 3
chr3_+_142315225 2.39 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr8_-_121457608 2.25 ENST00000306185.3
MRPL13
mitochondrial ribosomal protein L13
chr15_+_69854027 2.25 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr1_-_209975494 2.22 ENST00000456314.1
IRF6
interferon regulatory factor 6
chrX_-_33229636 2.18 ENST00000357033.4
DMD
dystrophin
chr10_+_28966271 2.17 ENST00000375533.3
BAMBI
BMP and activin membrane-bound inhibitor
chr15_-_86338100 2.16 ENST00000536947.1
KLHL25
kelch-like family member 25
chr12_-_118490403 2.14 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr19_+_2785458 2.13 ENST00000307741.6
ENST00000585338.1
THOP1
thimet oligopeptidase 1
chr7_+_99425633 2.06 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
CYP3A43
cytochrome P450, family 3, subfamily A, polypeptide 43
chr7_-_121944491 2.06 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr3_+_148415571 2.02 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr10_+_29135337 1.99 ENST00000375520.1
C10orf126
chromosome 10 open reading frame 126
chr3_-_187694195 1.99 ENST00000446091.1
RP11-132N15.3
RP11-132N15.3
chrX_+_10124977 1.98 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chrM_+_8366 1.95 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr18_-_31802056 1.93 ENST00000538587.1
NOL4
nucleolar protein 4
chr4_+_185734773 1.90 ENST00000508020.1
RP11-701P16.2
Uncharacterized protein
chr4_-_17513604 1.86 ENST00000505710.1
QDPR
quinoid dihydropteridine reductase
chr12_-_56359802 1.82 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
PMEL
premelanosome protein
chr10_-_35104185 1.81 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr2_-_86850949 1.81 ENST00000237455.4
RNF103
ring finger protein 103
chr8_-_27468717 1.81 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr13_-_30683005 1.81 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chrX_-_131262048 1.80 ENST00000298542.4
FRMD7
FERM domain containing 7
chr11_-_72385437 1.80 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr7_-_71912046 1.75 ENST00000395276.2
ENST00000431984.1
CALN1
calneuron 1
chr1_+_10292308 1.71 ENST00000377081.1
KIF1B
kinesin family member 1B
chr16_-_73178346 1.71 ENST00000358463.2
C16orf47
chromosome 16 open reading frame 47
chr3_+_32280159 1.69 ENST00000458535.2
ENST00000307526.3
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr15_-_86338134 1.68 ENST00000337975.5
KLHL25
kelch-like family member 25
chr13_+_30002741 1.66 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr5_-_156362666 1.65 ENST00000406964.1
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr8_+_22601 1.63 ENST00000522481.3
ENST00000518652.1
AC144568.2
Uncharacterized protein
chrM_+_8527 1.63 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr12_-_118490217 1.61 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr3_+_40141502 1.60 ENST00000539167.1
MYRIP
myosin VIIA and Rab interacting protein
chr17_-_26733604 1.60 ENST00000584426.1
ENST00000584995.1
SLC46A1
solute carrier family 46 (folate transporter), member 1
chr12_-_96336369 1.58 ENST00000546947.1
ENST00000546386.1
CCDC38
coiled-coil domain containing 38
chr1_+_26496362 1.58 ENST00000374266.5
ENST00000270812.5
ZNF593
zinc finger protein 593
chr9_-_75653627 1.58 ENST00000446946.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr1_-_165667545 1.57 ENST00000538148.1
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr8_-_27468842 1.55 ENST00000523500.1
CLU
clusterin
chr22_-_36220420 1.54 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr16_-_18573396 1.53 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NOMO2
NODAL modulator 2
chr15_+_31196080 1.53 ENST00000561607.1
ENST00000565466.1
FAN1
FANCD2/FANCI-associated nuclease 1
chr9_+_130830451 1.52 ENST00000373068.2
ENST00000373069.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chrM_-_14670 1.49 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chrM_+_14741 1.36 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr1_-_162346657 1.33 ENST00000367935.5
C1orf111
chromosome 1 open reading frame 111
chr1_+_156589198 1.30 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr18_+_74207477 1.30 ENST00000532511.1
RP11-17M16.1
uncharacterized protein LOC400658
chr5_+_139175380 1.29 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr7_+_97736197 1.25 ENST00000297293.5
LMTK2
lemur tyrosine kinase 2
chr3_+_127770455 1.25 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr15_-_74421477 1.25 ENST00000514871.1
RP11-247C2.2
HCG2004779; Uncharacterized protein
chr21_+_17961006 1.21 ENST00000602323.1
LINC00478
long intergenic non-protein coding RNA 478
chr10_+_51576285 1.20 ENST00000443446.1
NCOA4
nuclear receptor coactivator 4
chr1_-_165414414 1.20 ENST00000359842.5
RXRG
retinoid X receptor, gamma
chr1_-_25747283 1.18 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE
Rh blood group, CcEe antigens
chr11_+_85359002 1.16 ENST00000528105.1
ENST00000304511.2
TMEM126A
transmembrane protein 126A
chr19_+_13135386 1.15 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr18_+_39739223 1.13 ENST00000601948.1
LINC00907
long intergenic non-protein coding RNA 907
chr11_+_134123389 1.12 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
ACAD8
acyl-CoA dehydrogenase family, member 8
chr16_+_16326352 1.11 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3
NODAL modulator 3
chr3_+_177545563 1.07 ENST00000434309.1
RP11-91K9.1
RP11-91K9.1
chr11_+_34999328 1.07 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr1_-_63782888 1.05 ENST00000436475.2
LINC00466
long intergenic non-protein coding RNA 466
chr22_+_51176624 1.04 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chr1_-_94586651 1.04 ENST00000535735.1
ENST00000370225.3
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr5_+_59726565 1.04 ENST00000412930.2
FKSG52
FKSG52
chr15_-_99789736 1.02 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
TTC23
tetratricopeptide repeat domain 23
chr18_-_31802282 1.02 ENST00000535475.1
NOL4
nucleolar protein 4
chr10_+_114133773 1.01 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_113933581 0.99 ENST00000307546.9
ENST00000369615.1
ENST00000369611.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr4_-_83483395 0.99 ENST00000515780.2
TMEM150C
transmembrane protein 150C
chr21_-_27107344 0.97 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr4_-_83483360 0.97 ENST00000449862.2
TMEM150C
transmembrane protein 150C
chr11_-_67407031 0.97 ENST00000335385.3
TBX10
T-box 10
chr11_+_5905501 0.96 ENST00000316987.2
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr19_-_6501778 0.95 ENST00000596291.1
TUBB4A
tubulin, beta 4A class IVa
chr13_+_111267866 0.93 ENST00000458711.2
ENST00000424185.2
ENST00000397191.4
ENST00000309957.2
CARKD
carbohydrate kinase domain containing
chr5_+_126984710 0.93 ENST00000379445.3
CTXN3
cortexin 3
chr22_-_26961328 0.91 ENST00000398110.2
TPST2
tyrosylprotein sulfotransferase 2
chr1_-_165668100 0.89 ENST00000354775.4
ALDH9A1
aldehyde dehydrogenase 9 family, member A1
chr12_-_106477805 0.88 ENST00000553094.1
ENST00000549704.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr3_+_98699880 0.88 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr1_+_113933371 0.88 ENST00000369617.4
MAGI3
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr5_-_151784838 0.87 ENST00000255262.3
NMUR2
neuromedin U receptor 2
chr21_-_27107198 0.86 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_+_50569575 0.85 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr7_-_6523688 0.84 ENST00000490996.1
KDELR2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr14_+_24407940 0.84 ENST00000354854.1
DHRS4-AS1
DHRS4-AS1
chr19_+_11200038 0.84 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR
low density lipoprotein receptor
chr21_-_27107283 0.83 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr1_-_116383322 0.83 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr10_+_70980051 0.82 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr4_+_130692778 0.81 ENST00000513875.1
ENST00000508724.1
RP11-422J15.1
RP11-422J15.1
chr3_+_101546827 0.81 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr13_+_52598827 0.80 ENST00000521776.2
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr12_-_10978957 0.79 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr1_-_202679535 0.79 ENST00000367268.4
SYT2
synaptotagmin II
chr11_-_126870683 0.79 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr6_+_108616243 0.77 ENST00000421954.1
LACE1
lactation elevated 1
chr19_+_37998031 0.76 ENST00000586138.1
ENST00000588578.1
ENST00000587986.1
ZNF793
zinc finger protein 793
chr1_-_116383738 0.74 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr3_-_46735155 0.73 ENST00000318962.4
ALS2CL
ALS2 C-terminal like
chr20_+_22034809 0.73 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr9_+_140135665 0.72 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr19_-_49243845 0.72 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr15_+_31196053 0.70 ENST00000561594.1
ENST00000362065.4
FAN1
FANCD2/FANCI-associated nuclease 1
chrX_-_30877837 0.69 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 30.5 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
5.5 27.7 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) positive regulation of phospholipid catabolic process(GO:0060697)
3.4 13.7 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
3.0 15.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
3.0 15.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.6 26.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
2.6 7.9 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
2.4 17.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
2.1 8.2 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
1.8 5.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.5 6.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.3 3.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
1.0 17.7 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
1.0 8.9 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
1.0 15.4 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.9 0.9 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.9 6.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.8 18.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 2.4 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.8 13.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.8 4.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.7 5.0 GO:1902896 terminal web assembly(GO:1902896)
0.7 17.2 GO:0007614 short-term memory(GO:0007614)
0.7 8.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.6 3.2 GO:0008050 female courtship behavior(GO:0008050)
0.6 2.9 GO:0019605 butyrate metabolic process(GO:0019605)
0.5 12.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.5 2.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.5 3.0 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.5 1.9 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.5 4.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.5 1.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 8.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 1.7 GO:1904647 response to rotenone(GO:1904647)
0.4 3.4 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.4 6.8 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.4 8.7 GO:0097264 self proteolysis(GO:0097264)
0.4 6.1 GO:0015747 urate transport(GO:0015747)
0.4 2.6 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.4 2.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 2.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 3.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.3 10.3 GO:0036315 cellular response to sterol(GO:0036315)
0.3 2.9 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.3 3.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.3 0.9 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.3 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 2.8 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 1.7 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.3 0.8 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.3 1.6 GO:0051958 methotrexate transport(GO:0051958)
0.3 1.6 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.2 0.7 GO:0002188 translation reinitiation(GO:0002188)
0.2 1.2 GO:0039019 pronephric nephron development(GO:0039019)
0.2 1.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 0.6 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.2 2.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 3.4 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 1.1 GO:0006574 valine catabolic process(GO:0006574)
0.2 6.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 12.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 11.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 1.9 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 2.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 2.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 0.5 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 16.9 GO:0046849 bone remodeling(GO:0046849)
0.1 0.4 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.5 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 2.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.6 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 3.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 3.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.9 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 1.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 1.6 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.8 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 3.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 1.2 GO:0021554 optic nerve development(GO:0021554)
0.1 0.9 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 2.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.8 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.8 GO:0032438 melanosome organization(GO:0032438)
0.0 0.9 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 2.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.9 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.6 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 6.6 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 4.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 4.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0006553 lysine metabolic process(GO:0006553)
0.0 1.5 GO:0031648 protein destabilization(GO:0031648)
0.0 4.7 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.3 GO:0033572 transferrin transport(GO:0033572)
0.0 1.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 2.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.9 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.5 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 2.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.5 GO:0061458 reproductive system development(GO:0061458)
0.0 0.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.7 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 2.4 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 6.3 GO:0007596 blood coagulation(GO:0007596)
0.0 0.1 GO:0015749 hexose transport(GO:0008645) monosaccharide transport(GO:0015749)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.9 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
3.1 27.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.9 18.6 GO:0005579 membrane attack complex(GO:0005579)
1.5 26.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 5.0 GO:1990357 terminal web(GO:1990357)
0.5 2.6 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4 10.9 GO:0005922 connexon complex(GO:0005922)
0.4 13.9 GO:0036019 endolysosome(GO:0036019)
0.3 1.0 GO:0043159 acrosomal matrix(GO:0043159)
0.3 6.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.3 3.4 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 12.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 51.8 GO:0072562 blood microparticle(GO:0072562)
0.2 2.8 GO:0033269 internode region of axon(GO:0033269)
0.2 8.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 26.5 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.9 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 1.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 2.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0071817 MMXD complex(GO:0071817)
0.1 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 6.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 16.8 GO:0005903 brush border(GO:0005903)
0.1 1.6 GO:0031045 dense core granule(GO:0031045)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.3 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 9.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 3.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 16.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 62.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 26.9 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.8 GO:0012505 endomembrane system(GO:0012505)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.7 GO:0005795 Golgi stack(GO:0005795)
0.0 2.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0070469 respiratory chain(GO:0070469)
0.0 1.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 36.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
3.9 15.4 GO:0019862 IgA binding(GO:0019862)
3.5 34.8 GO:0001849 complement component C1q binding(GO:0001849)
3.0 15.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
2.0 8.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.1 3.2 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.9 10.3 GO:0008142 oxysterol binding(GO:0008142)
0.8 5.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.7 30.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.7 2.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.7 2.8 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.7 2.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.7 2.6 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.7 4.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.6 12.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.6 18.6 GO:0001848 complement binding(GO:0001848)
0.6 1.9 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.5 1.6 GO:0031177 phosphopantetheine binding(GO:0031177)
0.5 16.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 10.9 GO:0005243 gap junction channel activity(GO:0005243)
0.5 13.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 8.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.4 2.9 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.4 8.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.4 6.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 11.3 GO:0051787 misfolded protein binding(GO:0051787)
0.3 15.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.3 1.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 1.6 GO:0015350 methotrexate transporter activity(GO:0015350)
0.3 1.0 GO:0004040 amidase activity(GO:0004040)
0.3 6.2 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.2 0.7 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 1.8 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 2.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 3.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.8 GO:0005046 KDEL sequence binding(GO:0005046)
0.2 0.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.6 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.2 2.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.2 2.7 GO:0005542 folic acid binding(GO:0005542)
0.2 1.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 1.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 3.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 3.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 4.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.3 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 3.7 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 6.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 3.0 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 28.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.1 0.8 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 2.1 GO:0070330 aromatase activity(GO:0070330)
0.1 17.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 8.5 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.8 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 2.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.4 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 19.3 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 10.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 2.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 4.0 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.0 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 6.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 2.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 7.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.2 GO:0043022 ribosome binding(GO:0043022)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 45.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 27.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 71.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 14.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 7.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 5.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 7.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 17.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
1.0 45.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.0 27.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.7 15.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.6 25.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 15.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.4 10.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 3.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 5.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 12.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.2 3.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 6.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 15.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 12.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 8.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 2.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 12.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 10.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 2.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 6.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors