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Illumina Body Map 2: averaged replicates

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Results for PBX1

Z-value: 1.47

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
PBX1
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164528616_164528660-0.392.7e-02Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_29171689 7.63 ENST00000237014.3
TTR
transthyretin
chr4_-_72649763 5.10 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr17_-_26694979 4.60 ENST00000438614.1
VTN
vitronectin
chr17_-_26695013 4.46 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr13_-_46679144 3.96 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr13_-_46679185 3.84 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr4_+_69962185 3.75 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_+_20968608 3.59 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr2_-_88427568 3.56 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr4_+_69962212 3.51 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_+_81471816 3.20 ENST00000261206.3
ACSS3
acyl-CoA synthetase short-chain family member 3
chr19_-_16008880 3.13 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr4_+_69681710 3.13 ENST00000265403.7
ENST00000458688.2
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_+_211342432 2.65 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr10_-_101190202 2.50 ENST00000543866.1
ENST00000370508.5
GOT1
glutamic-oxaloacetic transaminase 1, soluble
chr4_+_187148556 2.40 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr5_-_42825983 2.37 ENST00000506577.1
SEPP1
selenoprotein P, plasma, 1
chr10_+_5238793 2.35 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr2_+_234600253 2.19 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr4_-_69536346 2.18 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr6_+_25754927 2.15 ENST00000377905.4
ENST00000439485.2
SLC17A4
solute carrier family 17, member 4
chrM_+_4431 2.15 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr12_+_21679220 2.13 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr4_-_70080449 2.12 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr14_-_74551096 1.94 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_+_96522361 1.86 ENST00000371321.3
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr11_+_22689648 1.85 ENST00000278187.3
GAS2
growth arrest-specific 2
chr19_-_15590306 1.84 ENST00000292609.4
PGLYRP2
peptidoglycan recognition protein 2
chr11_-_2162162 1.83 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr7_+_107110488 1.82 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr18_-_48346298 1.79 ENST00000398439.3
MRO
maestro
chr14_-_74551172 1.79 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrM_-_14670 1.77 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr18_-_48346415 1.70 ENST00000431965.2
ENST00000436348.2
MRO
maestro
chr17_+_4853442 1.68 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr17_-_38821373 1.65 ENST00000394052.3
KRT222
keratin 222
chr3_+_159557637 1.58 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr5_+_166711804 1.57 ENST00000518659.1
ENST00000545108.1
TENM2
teneurin transmembrane protein 2
chr6_-_110736742 1.57 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr4_+_77356248 1.55 ENST00000296043.6
SHROOM3
shroom family member 3
chr10_+_24738355 1.53 ENST00000307544.6
KIAA1217
KIAA1217
chr8_+_99076509 1.52 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr11_+_114166536 1.52 ENST00000299964.3
NNMT
nicotinamide N-methyltransferase
chr12_-_96389702 1.50 ENST00000552509.1
HAL
histidine ammonia-lyase
chr8_+_99076750 1.49 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr6_-_26124138 1.48 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr14_+_24584056 1.48 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr7_-_120498357 1.45 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12
tetraspanin 12
chr1_+_156589198 1.43 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr15_-_54025300 1.43 ENST00000559418.1
WDR72
WD repeat domain 72
chr18_+_44526744 1.42 ENST00000585469.1
KATNAL2
katanin p60 subunit A-like 2
chr14_+_24584372 1.38 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DCAF11
DDB1 and CUL4 associated factor 11
chr5_-_125930877 1.37 ENST00000510111.2
ENST00000509270.1
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chrM_+_14741 1.37 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr5_+_43602750 1.36 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr19_-_33360647 1.34 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr2_-_200323414 1.27 ENST00000443023.1
SATB2
SATB homeobox 2
chr11_-_126870683 1.24 ENST00000525704.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr14_+_24583836 1.24 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11
DDB1 and CUL4 associated factor 11
chr17_+_58018269 1.24 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr5_+_43603229 1.24 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr8_-_42360015 1.23 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr5_-_125930929 1.21 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr8_-_36636676 1.20 ENST00000524132.1
ENST00000519451.1
RP11-962G15.1
RP11-962G15.1
chr22_+_29138013 1.16 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr12_+_79258444 1.16 ENST00000261205.4
SYT1
synaptotagmin I
chr4_-_152147579 1.15 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr16_+_7560114 1.10 ENST00000570626.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr18_+_44526786 1.08 ENST00000245121.5
ENST00000356157.7
KATNAL2
katanin p60 subunit A-like 2
chr4_-_6557336 1.05 ENST00000507294.1
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr9_+_140135665 1.04 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr4_-_186570679 1.02 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr3_+_159570722 1.02 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr14_+_50234309 1.02 ENST00000298307.5
KLHDC2
kelch domain containing 2
chrM_+_9207 1.00 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr11_-_126870655 1.00 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr11_+_34938119 0.99 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X
chr4_-_186682716 0.98 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr5_-_43313574 0.97 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr15_-_37393406 0.96 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr1_+_156589051 0.95 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr8_-_91095099 0.94 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr3_+_139063372 0.94 ENST00000478464.1
MRPS22
mitochondrial ribosomal protein S22
chr2_-_158182410 0.93 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr6_+_26124373 0.91 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr12_-_39734783 0.89 ENST00000552961.1
KIF21A
kinesin family member 21A
chr10_+_69865866 0.88 ENST00000354393.2
MYPN
myopalladin
chr14_-_64971893 0.87 ENST00000555220.1
ZBTB25
zinc finger and BTB domain containing 25
chr13_-_48612067 0.87 ENST00000543413.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr20_+_48909240 0.84 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr2_-_200322723 0.84 ENST00000417098.1
SATB2
SATB homeobox 2
chr17_+_1665345 0.83 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_95517660 0.83 ENST00000371413.3
LGI1
leucine-rich, glioma inactivated 1
chr20_+_58203664 0.82 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr10_+_69869237 0.82 ENST00000373675.3
MYPN
myopalladin
chr1_+_205473720 0.81 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18
cyclin-dependent kinase 18
chr3_+_186743261 0.80 ENST00000423451.1
ENST00000446170.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_+_21525818 0.80 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr16_+_19222479 0.79 ENST00000568433.1
SYT17
synaptotagmin XVII
chr3_-_129375556 0.79 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr4_+_83956237 0.79 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr10_-_5227096 0.78 ENST00000488756.1
ENST00000334314.3
AKR1CL1
aldo-keto reductase family 1, member C-like 1
chr3_-_178103144 0.78 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr10_-_18948208 0.78 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr16_+_69458537 0.77 ENST00000515314.1
ENST00000561792.1
ENST00000568237.1
CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
chr4_+_83956312 0.76 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr2_+_79412357 0.76 ENST00000466387.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr2_+_44396000 0.75 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr4_+_118349545 0.74 ENST00000422145.3
ENST00000437514.1
AC092661.1
AC092661.1
chr10_+_95517616 0.74 ENST00000371418.4
LGI1
leucine-rich, glioma inactivated 1
chr17_-_57604227 0.73 ENST00000584262.1
RP11-567L7.6
RP11-567L7.6
chr4_-_48014931 0.71 ENST00000420489.2
ENST00000504722.1
CNGA1
cyclic nucleotide gated channel alpha 1
chr6_-_84417633 0.71 ENST00000521931.1
SNAP91
synaptosomal-associated protein, 91kDa
chrX_+_139791917 0.71 ENST00000607004.1
ENST00000370535.3
LINC00632
long intergenic non-protein coding RNA 632
chr12_-_56848426 0.70 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr9_-_73736511 0.70 ENST00000377110.3
ENST00000377111.2
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr10_+_114043493 0.69 ENST00000369422.3
TECTB
tectorin beta
chrX_+_120181457 0.69 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr17_+_46125685 0.68 ENST00000579889.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr2_+_201242715 0.68 ENST00000421573.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_79258547 0.67 ENST00000457153.2
SYT1
synaptotagmin I
chr21_+_44313375 0.67 ENST00000354250.2
ENST00000340344.4
NDUFV3
NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa
chr4_-_70626430 0.67 ENST00000310613.3
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chrX_+_125953746 0.67 ENST00000371125.3
CXorf64
chromosome X open reading frame 64
chr12_+_21168630 0.65 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_-_106477805 0.65 ENST00000553094.1
ENST00000549704.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr13_-_33760216 0.65 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr21_+_27543175 0.64 ENST00000608591.1
ENST00000609365.1
AP000230.1
AP000230.1
chr13_+_95254085 0.64 ENST00000376958.4
GPR180
G protein-coupled receptor 180
chr21_-_35014027 0.63 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
CRYZL1
crystallin, zeta (quinone reductase)-like 1
chr4_-_140005341 0.62 ENST00000379549.2
ENST00000512627.1
ELF2
E74-like factor 2 (ets domain transcription factor)
chr2_-_158182322 0.62 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr16_+_15596123 0.62 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr19_-_51141196 0.61 ENST00000338916.4
SYT3
synaptotagmin III
chr3_+_148508845 0.61 ENST00000491148.1
CPB1
carboxypeptidase B1 (tissue)
chr5_-_133702761 0.60 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
CDKL3
cyclin-dependent kinase-like 3
chr2_+_201242941 0.59 ENST00000449647.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr5_+_68513622 0.58 ENST00000512880.1
ENST00000602380.1
MRPS36
mitochondrial ribosomal protein S36
chr10_+_60028818 0.58 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr9_-_32573130 0.57 ENST00000350021.2
ENST00000379847.3
NDUFB6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr6_-_84418432 0.56 ENST00000519825.1
ENST00000523484.2
SNAP91
synaptosomal-associated protein, 91kDa
chr14_-_36536396 0.56 ENST00000546376.1
RP11-116N8.4
RP11-116N8.4
chr10_+_95517566 0.56 ENST00000542308.1
LGI1
leucine-rich, glioma inactivated 1
chr1_-_238108575 0.55 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr10_+_18689637 0.55 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_-_133787772 0.55 ENST00000545350.1
AC226150.4
Uncharacterized protein
chr14_-_24584138 0.55 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr9_-_101471479 0.54 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_167040693 0.53 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_-_92928557 0.53 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr12_-_10962767 0.50 ENST00000240691.2
TAS2R9
taste receptor, type 2, member 9
chr6_+_36839616 0.50 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chrX_-_63005405 0.50 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr4_-_105416039 0.49 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_-_140005443 0.48 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
ELF2
E74-like factor 2 (ets domain transcription factor)
chr12_+_123944070 0.47 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr12_-_54653313 0.47 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr6_-_167040731 0.47 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr13_+_97928395 0.44 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr19_-_5903714 0.44 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr2_-_158182105 0.43 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr14_+_88851874 0.43 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr19_+_12203100 0.43 ENST00000596883.1
ZNF788
zinc finger family member 788
chr5_-_86708833 0.42 ENST00000256897.4
CCNH
cyclin H
chr9_-_14308004 0.42 ENST00000493697.1
NFIB
nuclear factor I/B
chr16_-_63651939 0.42 ENST00000563855.1
ENST00000568932.1
ENST00000564290.1
RP11-368L12.1
RP11-368L12.1
chr3_-_169587621 0.42 ENST00000523069.1
ENST00000316428.5
ENST00000264676.5
LRRC31
leucine rich repeat containing 31
chr17_+_46125707 0.41 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr4_-_184241927 0.40 ENST00000323319.5
CLDN22
claudin 22
chr15_+_36871983 0.39 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chrM_+_10053 0.39 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr6_+_99282570 0.39 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr22_+_29834572 0.38 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr1_-_3713042 0.38 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr16_+_19079215 0.38 ENST00000544894.2
ENST00000561858.1
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr19_+_14640372 0.37 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
TECR
trans-2,3-enoyl-CoA reductase
chr19_+_58341656 0.37 ENST00000442832.4
ENST00000594901.1
ZNF587B
zinc finger protein 587B
chr16_-_88729473 0.37 ENST00000301012.3
ENST00000569177.1
MVD
mevalonate (diphospho) decarboxylase
chr7_+_7196565 0.37 ENST00000429911.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chrX_+_92929192 0.37 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chr3_-_38835501 0.37 ENST00000449082.2
SCN10A
sodium channel, voltage-gated, type X, alpha subunit
chr2_+_27886330 0.36 ENST00000326019.6
SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr19_-_58400148 0.36 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814
zinc finger protein 814
chr11_-_34938039 0.36 ENST00000395787.3
APIP
APAF1 interacting protein
chr12_-_24097236 0.36 ENST00000538083.1
SOX5
SRY (sex determining region Y)-box 5
chr3_+_161214596 0.35 ENST00000327928.4
OTOL1
otolin 1
chrX_+_119737806 0.35 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr17_+_21030260 0.34 ENST00000579303.1
DHRS7B
dehydrogenase/reductase (SDR family) member 7B
chr15_+_74421961 0.34 ENST00000565159.1
ENST00000567206.1
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_-_113437328 0.34 ENST00000313341.3
NEUROG2
neurogenin 2
chr4_+_120056939 0.33 ENST00000307128.5
MYOZ2
myozenin 2
chr17_+_43239191 0.33 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr16_-_20416053 0.33 ENST00000302451.4
PDILT
protein disulfide isomerase-like, testis expressed
chr5_-_86708670 0.33 ENST00000504878.1
CCNH
cyclin H
chr1_-_98511756 0.33 ENST00000602984.1
ENST00000602852.1
MIR137HG
MIR137 host gene (non-protein coding)
chr17_+_43239231 0.32 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr22_+_31795509 0.32 ENST00000331457.4
DRG1
developmentally regulated GTP binding protein 1
chr7_+_16700806 0.32 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr16_-_70323422 0.32 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chrX_-_70473957 0.31 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3
zinc finger, MYM-type 3

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0 3.1 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.9 3.7 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.9 2.7 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.8 2.5 GO:0006106 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.8 2.4 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.7 2.2 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.6 2.6 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.6 1.8 GO:0032824 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.5 7.6 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 1.6 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.5 11.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.4 2.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.4 2.6 GO:0006740 NADPH regeneration(GO:0006740)
0.3 1.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 2.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.3 1.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.2 4.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.9 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 1.5 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 3.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 3.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.2 1.3 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.8 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 1.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 2.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 5.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.8 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.9 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.0 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 3.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.8 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 4.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.6 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.7 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.6 GO:0019236 response to pheromone(GO:0019236)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 1.5 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.6 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.1 6.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.6 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 1.7 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.3 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.7 GO:0006538 glutamate biosynthetic process(GO:0006537) glutamate catabolic process(GO:0006538)
0.1 0.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.7 GO:0009812 flavonoid metabolic process(GO:0009812)
0.1 2.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 1.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 2.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.9 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.0 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.4 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.8 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:0030497 fatty acid elongation(GO:0030497)
0.0 1.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 1.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.2 GO:0071233 cellular response to leucine(GO:0071233)
0.0 1.2 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.7 GO:0006833 water transport(GO:0006833)
0.0 0.7 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.6 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 3.6 GO:0045179 apical cortex(GO:0045179)
0.2 0.7 GO:0070985 TFIIK complex(GO:0070985)
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.0 GO:0033269 internode region of axon(GO:0033269)
0.1 0.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 9.6 GO:0070469 respiratory chain(GO:0070469)
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 2.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 5.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 4.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.4 GO:0043679 axon terminus(GO:0043679)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 9.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.5 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 17.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 2.0 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:1902271 D3 vitamins binding(GO:1902271)
1.0 3.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.9 2.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.8 2.5 GO:0070546 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.7 2.7 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.5 3.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.5 1.5 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.5 7.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.5 2.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.5 1.8 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.4 3.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.4 1.5 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3 0.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 1.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.3 15.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.9 GO:0005499 vitamin D binding(GO:0005499)
0.2 2.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 8.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.9 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 3.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.2 1.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 1.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 4.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 4.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 1.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 3.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 5.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.4 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 1.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 0.6 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 1.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 1.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 1.7 GO:0030276 clathrin binding(GO:0030276)
0.0 3.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 8.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 3.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.2 2.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 3.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 3.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 5.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.4 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 5.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 6.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 4.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination