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Illumina Body Map 2: averaged replicates
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Results for PDX1
Z-value: 1.87
Motif logo
Transcription factors associated with PDX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PDX1
|
ENSG00000139515.5 | pancreatic and duodenal homeobox 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PDX1 | hg19_v2_chr13_+_28494130_28494168 | -0.10 | 6.0e-01 | Click! |
Activity profile of PDX1 motif
Sorted Z-values of PDX1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_-_32157947 | 7.57 |
ENST00000375050.4
|
PBX2
|
pre-B-cell leukemia homeobox 2 |
| chr13_-_46716969 | 6.56 |
ENST00000435666.2
|
LCP1
|
lymphocyte cytosolic protein 1 (L-plastin) |
| chr4_-_36245561 | 5.85 |
ENST00000506189.1
|
ARAP2
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| chr15_+_75080883 | 5.30 |
ENST00000567571.1
|
CSK
|
c-src tyrosine kinase |
| chr7_+_50348268 | 4.87 |
ENST00000438033.1
ENST00000439701.1 |
IKZF1
|
IKAROS family zinc finger 1 (Ikaros) |
| chr1_+_198607801 | 4.76 |
ENST00000367379.1
|
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr12_-_45269251 | 4.36 |
ENST00000553120.1
|
NELL2
|
NEL-like 2 (chicken) |
| chr3_+_108541608 | 4.35 |
ENST00000426646.1
|
TRAT1
|
T cell receptor associated transmembrane adaptor 1 |
| chr3_-_39321512 | 4.27 |
ENST00000399220.2
|
CX3CR1
|
chemokine (C-X3-C motif) receptor 1 |
| chr3_+_108541545 | 4.26 |
ENST00000295756.6
|
TRAT1
|
T cell receptor associated transmembrane adaptor 1 |
| chr1_+_198608292 | 4.00 |
ENST00000418674.1
|
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr1_+_198608146 | 3.89 |
ENST00000367376.2
ENST00000352140.3 ENST00000594404.1 ENST00000598951.1 ENST00000530727.1 ENST00000442510.2 ENST00000367367.4 ENST00000348564.6 ENST00000367364.1 ENST00000413409.2 |
PTPRC
|
protein tyrosine phosphatase, receptor type, C |
| chr14_+_22564294 | 3.67 |
ENST00000390452.2
|
TRDV1
|
T cell receptor delta variable 1 |
| chr11_-_118083600 | 3.60 |
ENST00000524477.1
|
AMICA1
|
adhesion molecule, interacts with CXADR antigen 1 |
| chr18_-_30353025 | 3.59 |
ENST00000359358.4
|
KLHL14
|
kelch-like family member 14 |
| chr15_+_58430368 | 3.57 |
ENST00000558772.1
ENST00000219919.4 |
AQP9
|
aquaporin 9 |
| chr4_-_155533787 | 3.56 |
ENST00000407946.1
ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1 |
FGG
|
fibrinogen gamma chain |
| chr8_+_32579341 | 3.54 |
ENST00000519240.1
ENST00000539990.1 |
NRG1
|
neuregulin 1 |
| chr14_+_100485712 | 3.50 |
ENST00000544450.2
|
EVL
|
Enah/Vasp-like |
| chr8_+_32579321 | 3.48 |
ENST00000522402.1
|
NRG1
|
neuregulin 1 |
| chr6_-_25042231 | 3.45 |
ENST00000510784.2
|
FAM65B
|
family with sequence similarity 65, member B |
| chr15_-_55563072 | 3.40 |
ENST00000567380.1
ENST00000565972.1 ENST00000569493.1 |
RAB27A
|
RAB27A, member RAS oncogene family |
| chr15_-_55562479 | 3.37 |
ENST00000564609.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr15_+_58430567 | 3.37 |
ENST00000536493.1
|
AQP9
|
aquaporin 9 |
| chr15_-_55562451 | 3.31 |
ENST00000568803.1
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr14_+_22554680 | 3.31 |
ENST00000390451.2
|
TRAV23DV6
|
T cell receptor alpha variable 23/delta variable 6 |
| chrX_+_123097014 | 3.25 |
ENST00000394478.1
|
STAG2
|
stromal antigen 2 |
| chr8_+_32579271 | 3.16 |
ENST00000518084.1
|
NRG1
|
neuregulin 1 |
| chr5_+_156712372 | 3.12 |
ENST00000541131.1
|
CYFIP2
|
cytoplasmic FMR1 interacting protein 2 |
| chr15_-_55562582 | 3.10 |
ENST00000396307.2
|
RAB27A
|
RAB27A, member RAS oncogene family |
| chr14_+_52313833 | 3.07 |
ENST00000553560.1
|
GNG2
|
guanine nucleotide binding protein (G protein), gamma 2 |
| chr7_+_37723336 | 2.99 |
ENST00000450180.1
|
GPR141
|
G protein-coupled receptor 141 |
| chr14_+_61654271 | 2.86 |
ENST00000555185.1
ENST00000557294.1 ENST00000556778.1 |
PRKCH
|
protein kinase C, eta |
| chr12_+_56325812 | 2.83 |
ENST00000394147.1
ENST00000551156.1 ENST00000553783.1 ENST00000557080.1 ENST00000432422.3 ENST00000556001.1 |
DGKA
|
diacylglycerol kinase, alpha 80kDa |
| chr14_-_69261310 | 2.82 |
ENST00000336440.3
|
ZFP36L1
|
ZFP36 ring finger protein-like 1 |
| chr5_+_173930676 | 2.71 |
ENST00000504512.1
|
RP11-267A15.1
|
RP11-267A15.1 |
| chr6_-_154568815 | 2.68 |
ENST00000519344.1
|
IPCEF1
|
interaction protein for cytohesin exchange factors 1 |
| chr11_+_4510109 | 2.66 |
ENST00000307632.3
|
OR52K1
|
olfactory receptor, family 52, subfamily K, member 1 |
| chr1_+_101003687 | 2.63 |
ENST00000315033.4
|
GPR88
|
G protein-coupled receptor 88 |
| chr14_+_72052983 | 2.60 |
ENST00000358550.2
|
SIPA1L1
|
signal-induced proliferation-associated 1 like 1 |
| chrX_-_20236970 | 2.57 |
ENST00000379548.4
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| chr5_+_173930710 | 2.51 |
ENST00000511707.1
|
RP11-267A15.1
|
RP11-267A15.1 |
| chr12_+_107712173 | 2.47 |
ENST00000280758.5
ENST00000420571.2 |
BTBD11
|
BTB (POZ) domain containing 11 |
| chr2_-_145188137 | 2.36 |
ENST00000440875.1
|
ZEB2
|
zinc finger E-box binding homeobox 2 |
| chr11_+_35222629 | 2.25 |
ENST00000526553.1
|
CD44
|
CD44 molecule (Indian blood group) |
| chr18_+_57567180 | 2.24 |
ENST00000316660.6
ENST00000269518.9 |
PMAIP1
|
phorbol-12-myristate-13-acetate-induced protein 1 |
| chr7_+_129015484 | 2.22 |
ENST00000490911.1
|
AHCYL2
|
adenosylhomocysteinase-like 2 |
| chr2_-_145277569 | 2.22 |
ENST00000303660.4
|
ZEB2
|
zinc finger E-box binding homeobox 2 |
| chr6_-_9933500 | 2.20 |
ENST00000492169.1
|
OFCC1
|
orofacial cleft 1 candidate 1 |
| chr20_-_31124186 | 2.20 |
ENST00000375678.3
|
C20orf112
|
chromosome 20 open reading frame 112 |
| chr14_-_36988882 | 2.18 |
ENST00000498187.2
|
NKX2-1
|
NK2 homeobox 1 |
| chrX_-_20237059 | 2.15 |
ENST00000457145.1
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| chr15_+_91416092 | 2.14 |
ENST00000559353.1
|
FURIN
|
furin (paired basic amino acid cleaving enzyme) |
| chr12_+_56325231 | 2.13 |
ENST00000549368.1
|
DGKA
|
diacylglycerol kinase, alpha 80kDa |
| chr5_+_66300464 | 2.12 |
ENST00000436277.1
|
MAST4
|
microtubule associated serine/threonine kinase family member 4 |
| chr13_-_41593425 | 2.12 |
ENST00000239882.3
|
ELF1
|
E74-like factor 1 (ets domain transcription factor) |
| chr17_-_27467418 | 2.10 |
ENST00000528564.1
|
MYO18A
|
myosin XVIIIA |
| chr6_-_154568551 | 2.09 |
ENST00000519190.1
|
IPCEF1
|
interaction protein for cytohesin exchange factors 1 |
| chr16_+_53133070 | 2.09 |
ENST00000565832.1
|
CHD9
|
chromodomain helicase DNA binding protein 9 |
| chr13_+_78315528 | 2.06 |
ENST00000496045.1
|
SLAIN1
|
SLAIN motif family, member 1 |
| chr6_+_130339710 | 2.06 |
ENST00000526087.1
ENST00000533560.1 ENST00000361794.2 |
L3MBTL3
|
l(3)mbt-like 3 (Drosophila) |
| chr10_-_48416849 | 2.05 |
ENST00000249598.1
|
GDF2
|
growth differentiation factor 2 |
| chr13_+_78315466 | 2.03 |
ENST00000314070.5
ENST00000462234.1 |
SLAIN1
|
SLAIN motif family, member 1 |
| chr3_-_57233966 | 2.00 |
ENST00000473921.1
ENST00000295934.3 |
HESX1
|
HESX homeobox 1 |
| chr11_-_85430356 | 2.00 |
ENST00000526999.1
|
SYTL2
|
synaptotagmin-like 2 |
| chr7_-_115670792 | 1.90 |
ENST00000265440.7
ENST00000393485.1 |
TFEC
|
transcription factor EC |
| chr21_+_30672433 | 1.89 |
ENST00000451655.1
|
BACH1
|
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| chr7_-_81399329 | 1.89 |
ENST00000453411.1
ENST00000444829.2 |
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr6_-_116866773 | 1.86 |
ENST00000368602.3
|
TRAPPC3L
|
trafficking protein particle complex 3-like |
| chr14_+_22987424 | 1.75 |
ENST00000390511.1
|
TRAJ26
|
T cell receptor alpha joining 26 |
| chr9_+_136501478 | 1.74 |
ENST00000393056.2
ENST00000263611.2 |
DBH
|
dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
| chr4_-_123377880 | 1.74 |
ENST00000226730.4
|
IL2
|
interleukin 2 |
| chr8_+_9953214 | 1.68 |
ENST00000382490.5
|
MSRA
|
methionine sulfoxide reductase A |
| chr7_-_115670804 | 1.66 |
ENST00000320239.7
|
TFEC
|
transcription factor EC |
| chr21_-_15918618 | 1.66 |
ENST00000400564.1
ENST00000400566.1 |
SAMSN1
|
SAM domain, SH3 domain and nuclear localization signals 1 |
| chr2_-_8715616 | 1.66 |
ENST00000418358.1
|
AC011747.3
|
AC011747.3 |
| chr7_-_81399355 | 1.66 |
ENST00000457544.2
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr6_-_116833500 | 1.64 |
ENST00000356128.4
|
TRAPPC3L
|
trafficking protein particle complex 3-like |
| chr7_-_81399411 | 1.63 |
ENST00000423064.2
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr8_+_9953061 | 1.63 |
ENST00000522907.1
ENST00000528246.1 |
MSRA
|
methionine sulfoxide reductase A |
| chr7_+_129015671 | 1.58 |
ENST00000466993.1
|
AHCYL2
|
adenosylhomocysteinase-like 2 |
| chr7_-_81399438 | 1.57 |
ENST00000222390.5
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr18_-_44181442 | 1.55 |
ENST00000398722.4
|
LOXHD1
|
lipoxygenase homology domains 1 |
| chr11_-_85430204 | 1.53 |
ENST00000389958.3
ENST00000527794.1 |
SYTL2
|
synaptotagmin-like 2 |
| chr12_+_50144381 | 1.52 |
ENST00000552370.1
|
TMBIM6
|
transmembrane BAX inhibitor motif containing 6 |
| chr12_+_28410128 | 1.50 |
ENST00000381259.1
ENST00000381256.1 |
CCDC91
|
coiled-coil domain containing 91 |
| chr5_-_140998616 | 1.49 |
ENST00000389054.3
ENST00000398562.2 ENST00000389057.5 ENST00000398566.3 ENST00000398557.4 ENST00000253811.6 |
DIAPH1
|
diaphanous-related formin 1 |
| chr11_-_85430088 | 1.48 |
ENST00000533057.1
ENST00000533892.1 |
SYTL2
|
synaptotagmin-like 2 |
| chr14_+_22985251 | 1.48 |
ENST00000390510.1
|
TRAJ27
|
T cell receptor alpha joining 27 |
| chr11_-_85430163 | 1.47 |
ENST00000529581.1
ENST00000533577.1 |
SYTL2
|
synaptotagmin-like 2 |
| chr7_-_92777606 | 1.46 |
ENST00000437805.1
ENST00000446959.1 ENST00000439952.1 ENST00000414791.1 ENST00000446033.1 ENST00000411955.1 ENST00000318238.4 |
SAMD9L
|
sterile alpha motif domain containing 9-like |
| chr2_+_45168875 | 1.46 |
ENST00000260653.3
|
SIX3
|
SIX homeobox 3 |
| chr5_-_76935513 | 1.45 |
ENST00000306422.3
|
OTP
|
orthopedia homeobox |
| chr14_+_22992573 | 1.44 |
ENST00000390516.1
|
TRAJ21
|
T cell receptor alpha joining 21 |
| chrX_-_19817869 | 1.44 |
ENST00000379698.4
|
SH3KBP1
|
SH3-domain kinase binding protein 1 |
| chr4_+_141445333 | 1.43 |
ENST00000507667.1
|
ELMOD2
|
ELMO/CED-12 domain containing 2 |
| chr9_-_123639445 | 1.42 |
ENST00000312189.6
|
PHF19
|
PHD finger protein 19 |
| chr2_+_87769459 | 1.39 |
ENST00000414030.1
ENST00000437561.1 |
LINC00152
|
long intergenic non-protein coding RNA 152 |
| chr17_-_27418537 | 1.38 |
ENST00000408971.2
|
TIAF1
|
TGFB1-induced anti-apoptotic factor 1 |
| chr2_+_234959376 | 1.34 |
ENST00000425558.1
|
SPP2
|
secreted phosphoprotein 2, 24kDa |
| chr4_-_116034979 | 1.32 |
ENST00000264363.2
|
NDST4
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 |
| chr12_+_47610315 | 1.32 |
ENST00000548348.1
ENST00000549500.1 |
PCED1B
|
PC-esterase domain containing 1B |
| chr5_+_135394840 | 1.30 |
ENST00000503087.1
|
TGFBI
|
transforming growth factor, beta-induced, 68kDa |
| chr17_-_57229155 | 1.30 |
ENST00000584089.1
|
SKA2
|
spindle and kinetochore associated complex subunit 2 |
| chr2_-_112237835 | 1.29 |
ENST00000442293.1
ENST00000439494.1 |
MIR4435-1HG
|
MIR4435-1 host gene (non-protein coding) |
| chr10_+_11047259 | 1.28 |
ENST00000379261.4
ENST00000416382.2 |
CELF2
|
CUGBP, Elav-like family member 2 |
| chr18_-_46784778 | 1.26 |
ENST00000582399.1
|
DYM
|
dymeclin |
| chr10_+_114710425 | 1.26 |
ENST00000352065.5
ENST00000369395.1 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
| chr2_-_61697862 | 1.26 |
ENST00000398571.2
|
USP34
|
ubiquitin specific peptidase 34 |
| chr5_-_134735568 | 1.26 |
ENST00000510038.1
ENST00000304332.4 |
H2AFY
|
H2A histone family, member Y |
| chr21_+_30673091 | 1.24 |
ENST00000447177.1
|
BACH1
|
BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| chr16_-_69390209 | 1.23 |
ENST00000563634.1
|
RP11-343C2.9
|
Uncharacterized protein |
| chr15_-_98836406 | 1.22 |
ENST00000560360.1
|
CTD-2544M6.1
|
CTD-2544M6.1 |
| chr8_-_42234745 | 1.21 |
ENST00000220812.2
|
DKK4
|
dickkopf WNT signaling pathway inhibitor 4 |
| chrX_+_591524 | 1.21 |
ENST00000554971.1
ENST00000381575.1 |
SHOX
|
short stature homeobox |
| chr18_-_53019208 | 1.20 |
ENST00000562607.1
|
TCF4
|
transcription factor 4 |
| chr5_+_137722255 | 1.19 |
ENST00000542866.1
|
KDM3B
|
lysine (K)-specific demethylase 3B |
| chr5_-_142780280 | 1.17 |
ENST00000424646.2
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| chr10_+_114710211 | 1.17 |
ENST00000349937.2
ENST00000369397.4 |
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box) |
| chr1_-_1709845 | 1.17 |
ENST00000341426.5
ENST00000344463.4 |
NADK
|
NAD kinase |
| chr12_-_103344615 | 1.16 |
ENST00000546844.1
|
PAH
|
phenylalanine hydroxylase |
| chrX_-_110655306 | 1.16 |
ENST00000371993.2
|
DCX
|
doublecortin |
| chr1_+_28586006 | 1.15 |
ENST00000253063.3
|
SESN2
|
sestrin 2 |
| chr4_-_41884620 | 1.15 |
ENST00000504870.1
|
LINC00682
|
long intergenic non-protein coding RNA 682 |
| chr17_-_6983594 | 1.14 |
ENST00000571664.1
ENST00000254868.4 |
CLEC10A
|
C-type lectin domain family 10, member A |
| chr12_-_53729525 | 1.13 |
ENST00000303846.3
|
SP7
|
Sp7 transcription factor |
| chr5_-_140998481 | 1.13 |
ENST00000518047.1
|
DIAPH1
|
diaphanous-related formin 1 |
| chr14_+_39944025 | 1.13 |
ENST00000554328.1
ENST00000556620.1 ENST00000557197.1 |
RP11-111A21.1
|
RP11-111A21.1 |
| chr1_-_1710229 | 1.13 |
ENST00000341991.3
|
NADK
|
NAD kinase |
| chr18_+_3447572 | 1.12 |
ENST00000548489.2
|
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr1_-_182641367 | 1.08 |
ENST00000508450.1
|
RGS8
|
regulator of G-protein signaling 8 |
| chr16_-_30457048 | 1.08 |
ENST00000500504.2
ENST00000542752.1 |
SEPHS2
|
selenophosphate synthetase 2 |
| chr4_+_66536248 | 1.08 |
ENST00000514260.1
ENST00000507117.1 |
RP11-807H7.1
|
RP11-807H7.1 |
| chr2_+_90060377 | 1.07 |
ENST00000436451.2
|
IGKV6D-21
|
immunoglobulin kappa variable 6D-21 (non-functional) |
| chr12_-_53730147 | 1.06 |
ENST00000536324.2
|
SP7
|
Sp7 transcription factor |
| chr5_-_54988448 | 1.06 |
ENST00000503817.1
ENST00000512595.1 |
SLC38A9
|
solute carrier family 38, member 9 |
| chr13_-_46626820 | 1.04 |
ENST00000428921.1
|
ZC3H13
|
zinc finger CCCH-type containing 13 |
| chr11_+_115498761 | 1.03 |
ENST00000424313.2
|
AP000997.1
|
AP000997.1 |
| chr17_-_40337470 | 1.03 |
ENST00000293330.1
|
HCRT
|
hypocretin (orexin) neuropeptide precursor |
| chr4_-_39979576 | 1.02 |
ENST00000303538.8
ENST00000503396.1 |
PDS5A
|
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) |
| chrX_-_21676442 | 1.01 |
ENST00000379499.2
|
KLHL34
|
kelch-like family member 34 |
| chr17_-_6983550 | 1.00 |
ENST00000576617.1
ENST00000416562.2 |
CLEC10A
|
C-type lectin domain family 10, member A |
| chr21_-_32253874 | 1.00 |
ENST00000332378.4
|
KRTAP11-1
|
keratin associated protein 11-1 |
| chr20_+_42523336 | 1.00 |
ENST00000428529.1
|
RP5-1030M6.3
|
RP5-1030M6.3 |
| chr20_+_11008408 | 0.99 |
ENST00000378252.1
|
C20orf187
|
chromosome 20 open reading frame 187 |
| chr1_-_68698197 | 0.97 |
ENST00000370973.2
ENST00000370971.1 |
WLS
|
wntless Wnt ligand secretion mediator |
| chr17_+_73452545 | 0.97 |
ENST00000314256.7
|
KIAA0195
|
KIAA0195 |
| chr1_-_151965048 | 0.97 |
ENST00000368809.1
|
S100A10
|
S100 calcium binding protein A10 |
| chr2_+_48541776 | 0.97 |
ENST00000413569.1
ENST00000340553.3 |
FOXN2
|
forkhead box N2 |
| chr12_-_54813229 | 0.95 |
ENST00000293379.4
|
ITGA5
|
integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| chr1_-_21625486 | 0.95 |
ENST00000481130.2
|
ECE1
|
endothelin converting enzyme 1 |
| chr20_+_30697298 | 0.92 |
ENST00000398022.2
|
TM9SF4
|
transmembrane 9 superfamily protein member 4 |
| chr17_-_39165366 | 0.92 |
ENST00000391588.1
|
KRTAP3-1
|
keratin associated protein 3-1 |
| chr6_+_49467671 | 0.91 |
ENST00000371197.4
ENST00000545705.1 |
GLYATL3
|
glycine-N-acyltransferase-like 3 |
| chr20_+_62795827 | 0.90 |
ENST00000328439.1
ENST00000536311.1 |
MYT1
|
myelin transcription factor 1 |
| chr3_-_131756559 | 0.90 |
ENST00000505957.1
|
CPNE4
|
copine IV |
| chr18_+_32558380 | 0.90 |
ENST00000588349.2
|
MAPRE2
|
microtubule-associated protein, RP/EB family, member 2 |
| chr4_-_119759795 | 0.90 |
ENST00000419654.2
|
SEC24D
|
SEC24 family member D |
| chr13_-_99667960 | 0.90 |
ENST00000448493.2
|
DOCK9
|
dedicator of cytokinesis 9 |
| chr1_+_159272111 | 0.90 |
ENST00000368114.1
|
FCER1A
|
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| chr7_-_81399287 | 0.89 |
ENST00000354224.6
|
HGF
|
hepatocyte growth factor (hepapoietin A; scatter factor) |
| chr19_+_50016610 | 0.88 |
ENST00000596975.1
|
FCGRT
|
Fc fragment of IgG, receptor, transporter, alpha |
| chr17_+_73539339 | 0.86 |
ENST00000581713.1
|
LLGL2
|
lethal giant larvae homolog 2 (Drosophila) |
| chr15_+_34260921 | 0.86 |
ENST00000560035.1
|
CHRM5
|
cholinergic receptor, muscarinic 5 |
| chr19_-_7698599 | 0.85 |
ENST00000311069.5
|
PCP2
|
Purkinje cell protein 2 |
| chr12_+_15699286 | 0.84 |
ENST00000442921.2
ENST00000542557.1 ENST00000445537.2 ENST00000544244.1 |
PTPRO
|
protein tyrosine phosphatase, receptor type, O |
| chr1_+_84609944 | 0.83 |
ENST00000370685.3
|
PRKACB
|
protein kinase, cAMP-dependent, catalytic, beta |
| chr17_-_9929581 | 0.82 |
ENST00000437099.2
ENST00000396115.2 |
GAS7
|
growth arrest-specific 7 |
| chr12_+_42725554 | 0.82 |
ENST00000546750.1
ENST00000547847.1 |
PPHLN1
|
periphilin 1 |
| chr9_+_135457530 | 0.81 |
ENST00000263610.2
|
BARHL1
|
BarH-like homeobox 1 |
| chr12_-_56321649 | 0.79 |
ENST00000454792.2
ENST00000408946.2 |
WIBG
|
within bgcn homolog (Drosophila) |
| chr1_+_36621174 | 0.79 |
ENST00000429533.2
|
MAP7D1
|
MAP7 domain containing 1 |
| chr1_+_66796401 | 0.78 |
ENST00000528771.1
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr14_-_95236551 | 0.78 |
ENST00000238558.3
|
GSC
|
goosecoid homeobox |
| chr14_-_57272366 | 0.78 |
ENST00000554788.1
ENST00000554845.1 ENST00000408990.3 |
OTX2
|
orthodenticle homeobox 2 |
| chr6_+_150920999 | 0.77 |
ENST00000367328.1
ENST00000367326.1 |
PLEKHG1
|
pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| chr4_+_105828492 | 0.77 |
ENST00000506148.1
|
RP11-556I14.1
|
RP11-556I14.1 |
| chr16_-_18066399 | 0.76 |
ENST00000569048.1
|
CTA-481E9.4
|
CTA-481E9.4 |
| chr20_+_43538756 | 0.75 |
ENST00000537323.1
ENST00000217073.2 |
PABPC1L
|
poly(A) binding protein, cytoplasmic 1-like |
| chr9_-_123639304 | 0.75 |
ENST00000436309.1
|
PHF19
|
PHD finger protein 19 |
| chr14_-_78083112 | 0.75 |
ENST00000216484.2
|
SPTLC2
|
serine palmitoyltransferase, long chain base subunit 2 |
| chr18_+_59000815 | 0.72 |
ENST00000262717.4
|
CDH20
|
cadherin 20, type 2 |
| chr8_-_9761693 | 0.71 |
ENST00000521863.1
|
LINC00599
|
long intergenic non-protein coding RNA 599 |
| chr4_+_169013666 | 0.70 |
ENST00000359299.3
|
ANXA10
|
annexin A10 |
| chr1_-_151431647 | 0.70 |
ENST00000368863.2
ENST00000409503.1 ENST00000491586.1 ENST00000533351.1 ENST00000540984.1 |
POGZ
|
pogo transposable element with ZNF domain |
| chr5_-_141249154 | 0.69 |
ENST00000357517.5
ENST00000536585.1 |
PCDH1
|
protocadherin 1 |
| chr15_+_69854027 | 0.69 |
ENST00000498938.2
|
RP11-279F6.1
|
RP11-279F6.1 |
| chr2_-_89459813 | 0.69 |
ENST00000390256.2
|
IGKV6-21
|
immunoglobulin kappa variable 6-21 (non-functional) |
| chr5_-_134871639 | 0.69 |
ENST00000314744.4
|
NEUROG1
|
neurogenin 1 |
| chr6_-_111136513 | 0.68 |
ENST00000368911.3
|
CDK19
|
cyclin-dependent kinase 19 |
| chr7_+_1272522 | 0.67 |
ENST00000316333.8
|
UNCX
|
UNC homeobox |
| chrX_-_133931164 | 0.67 |
ENST00000370790.1
ENST00000298090.6 |
FAM122B
|
family with sequence similarity 122B |
| chr12_-_53730126 | 0.67 |
ENST00000537210.2
|
SP7
|
Sp7 transcription factor |
| chr14_+_22947861 | 0.65 |
ENST00000390482.1
|
TRAJ57
|
T cell receptor alpha joining 57 |
| chr1_+_28261533 | 0.64 |
ENST00000411604.1
ENST00000373888.4 |
SMPDL3B
|
sphingomyelin phosphodiesterase, acid-like 3B |
| chr1_-_182640988 | 0.64 |
ENST00000367556.1
|
RGS8
|
regulator of G-protein signaling 8 |
| chr1_-_151431674 | 0.64 |
ENST00000531094.1
|
POGZ
|
pogo transposable element with ZNF domain |
| chr20_+_43538692 | 0.63 |
ENST00000217074.4
ENST00000255136.3 |
PABPC1L
|
poly(A) binding protein, cytoplasmic 1-like |
| chr13_-_67802549 | 0.63 |
ENST00000328454.5
ENST00000377865.2 |
PCDH9
|
protocadherin 9 |
| chr15_-_100882191 | 0.63 |
ENST00000268070.4
|
ADAMTS17
|
ADAM metallopeptidase with thrombospondin type 1 motif, 17 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PDX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 12.7 | GO:2000473 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
| 1.9 | 13.2 | GO:1903435 | positive regulation of constitutive secretory pathway(GO:1903435) |
| 1.4 | 4.3 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 1.2 | 6.9 | GO:0015722 | canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 1.0 | 10.2 | GO:0038129 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
| 1.0 | 8.6 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.7 | 1.5 | GO:0009946 | proximal/distal axis specification(GO:0009946) |
| 0.7 | 2.1 | GO:0032904 | viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 0.7 | 5.3 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.7 | 2.6 | GO:0061743 | motor learning(GO:0061743) |
| 0.6 | 3.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.6 | 7.6 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.6 | 2.8 | GO:1901545 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.5 | 2.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.5 | 4.6 | GO:1902748 | positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.5 | 3.8 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.4 | 6.5 | GO:0070257 | positive regulation of mucus secretion(GO:0070257) |
| 0.4 | 1.3 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 0.4 | 1.6 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.4 | 1.9 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 0.4 | 1.1 | GO:0016260 | selenocysteine biosynthetic process(GO:0016260) |
| 0.3 | 2.4 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.3 | 0.9 | GO:0060304 | regulation of phosphatidylinositol dephosphorylation(GO:0060304) |
| 0.3 | 0.9 | GO:0001812 | positive regulation of type I hypersensitivity(GO:0001812) |
| 0.3 | 0.9 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.3 | 2.3 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.3 | 0.8 | GO:0036060 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.3 | 2.9 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.3 | 0.8 | GO:0014034 | neural crest cell fate commitment(GO:0014034) |
| 0.3 | 6.7 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.3 | 3.3 | GO:0030091 | protein repair(GO:0030091) |
| 0.3 | 2.3 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.2 | 1.7 | GO:0042421 | norepinephrine biosynthetic process(GO:0042421) |
| 0.2 | 4.4 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.2 | 3.1 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.2 | 3.5 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.2 | 3.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.2 | 1.5 | GO:1904721 | negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.2 | 0.6 | GO:0070175 | positive regulation of enamel mineralization(GO:0070175) |
| 0.2 | 4.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.2 | 2.2 | GO:0021759 | globus pallidus development(GO:0021759) |
| 0.2 | 2.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.2 | 0.5 | GO:0098976 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.2 | 1.7 | GO:2000317 | negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320) |
| 0.2 | 7.6 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.2 | 1.0 | GO:0051970 | negative regulation of transmission of nerve impulse(GO:0051970) |
| 0.2 | 3.6 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.2 | 5.0 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.2 | 1.0 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.2 | 2.6 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.2 | 2.0 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.2 | 1.2 | GO:0051799 | negative regulation of hair follicle development(GO:0051799) |
| 0.1 | 2.2 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 0.1 | 2.1 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.7 | GO:0021650 | vestibulocochlear nerve formation(GO:0021650) |
| 0.1 | 5.1 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 2.6 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 0.6 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.1 | 2.3 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159) |
| 0.1 | 1.5 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.1 | 3.1 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 1.5 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.8 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.1 | 0.4 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 0.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.1 | 0.4 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.1 | 1.5 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.1 | 1.2 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.1 | 0.7 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.1 | 0.8 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 1.4 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.1 | 0.4 | GO:0001757 | somite specification(GO:0001757) |
| 0.1 | 1.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.1 | 0.4 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.1 | 2.1 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 1.3 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
| 0.1 | 1.0 | GO:0033631 | cell-cell adhesion mediated by integrin(GO:0033631) |
| 0.1 | 0.9 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 1.2 | GO:1902221 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.1 | 1.0 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.1 | 0.8 | GO:1901078 | negative regulation of relaxation of muscle(GO:1901078) |
| 0.1 | 0.3 | GO:0002501 | peptide antigen assembly with MHC protein complex(GO:0002501) |
| 0.1 | 0.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 1.0 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.1 | 0.3 | GO:0035513 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.0 | 1.1 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 0.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 0.9 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.3 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
| 0.0 | 0.2 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
| 0.0 | 0.9 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 1.9 | GO:0043537 | negative regulation of blood vessel endothelial cell migration(GO:0043537) |
| 0.0 | 0.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 1.3 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 1.7 | GO:0050869 | negative regulation of B cell activation(GO:0050869) |
| 0.0 | 0.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.0 | 0.4 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.0 | 2.6 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 0.6 | GO:0030900 | forebrain development(GO:0030900) |
| 0.0 | 0.4 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.2 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.0 | 5.1 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.0 | 0.3 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 0.6 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 2.7 | GO:2000738 | positive regulation of stem cell differentiation(GO:2000738) |
| 0.0 | 1.3 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.5 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.5 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.5 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 1.4 | GO:0042059 | negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) |
| 0.0 | 0.2 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.0 | 0.6 | GO:0072662 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.2 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.0 | 0.7 | GO:0050790 | regulation of catalytic activity(GO:0050790) |
| 0.0 | 0.8 | GO:0032008 | positive regulation of TOR signaling(GO:0032008) |
| 0.0 | 3.6 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.4 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.5 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.8 | GO:0030901 | midbrain development(GO:0030901) |
| 0.0 | 0.5 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
| 0.0 | 0.6 | GO:0021522 | spinal cord motor neuron differentiation(GO:0021522) |
| 0.0 | 0.6 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 0.5 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.0 | 0.2 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.5 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.0 | 1.3 | GO:0046849 | bone remodeling(GO:0046849) |
| 0.0 | 0.7 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.0 | 1.9 | GO:0050688 | regulation of defense response to virus(GO:0050688) |
| 0.0 | 1.3 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 10.0 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 2.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.3 | 2.3 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.3 | 4.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.3 | 3.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 1.0 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.2 | 8.6 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.2 | 3.5 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.2 | 10.2 | GO:0030673 | axolemma(GO:0030673) |
| 0.2 | 6.6 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 1.3 | GO:0001740 | Barr body(GO:0001740) |
| 0.2 | 6.5 | GO:0044298 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.1 | 1.7 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 0.3 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
| 0.1 | 1.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.1 | 0.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.1 | 1.3 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 1.3 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 7.7 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.3 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.1 | 0.5 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
| 0.1 | 2.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.1 | 7.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.8 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.9 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 1.6 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 12.0 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 0.4 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.4 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.3 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 13.4 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.4 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 1.3 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 2.5 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.3 | GO:0000801 | central element(GO:0000801) |
| 0.0 | 0.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 1.5 | GO:0016020 | membrane(GO:0016020) |
| 0.0 | 1.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.4 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.1 | GO:0000333 | telomerase catalytic core complex(GO:0000333) |
| 0.0 | 1.2 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.4 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.5 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.0 | 2.6 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 2.4 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.8 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 4.3 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.0 | 4.0 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 1.3 | GO:0000792 | heterochromatin(GO:0000792) |
| 0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 2.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 0.6 | GO:0005605 | basal lamina(GO:0005605) |
| 0.0 | 1.3 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 4.6 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.0 | GO:0035841 | new growing cell tip(GO:0035841) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.3 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 1.4 | 6.9 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.8 | 10.2 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.6 | 3.3 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.5 | 3.8 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.4 | 2.9 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.4 | 13.2 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.4 | 1.1 | GO:0016781 | selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781) |
| 0.3 | 13.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.3 | 8.6 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.2 | 6.5 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.2 | 1.1 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.2 | 1.7 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208) |
| 0.2 | 4.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.2 | 1.0 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.2 | 1.8 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
| 0.2 | 1.2 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.2 | 1.7 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 0.2 | 3.1 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.2 | 1.5 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.2 | 5.0 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.2 | 5.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 1.2 | GO:0070728 | leucine binding(GO:0070728) |
| 0.2 | 2.1 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.2 | 3.5 | GO:0005522 | profilin binding(GO:0005522) |
| 0.2 | 3.1 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 2.3 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 1.3 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
| 0.1 | 1.2 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.1 | 3.1 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.1 | 0.9 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 0.9 | GO:0047961 | glycine N-acyltransferase activity(GO:0047961) |
| 0.1 | 0.6 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) |
| 0.1 | 1.3 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.1 | 0.4 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.1 | 2.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.1 | 0.3 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 2.8 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 2.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 6.5 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 1.6 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.1 | 4.7 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.4 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 0.5 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 5.4 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.1 | 1.0 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 0.3 | GO:0072545 | tyrosine binding(GO:0072545) |
| 0.1 | 2.8 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 2.6 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 1.2 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 0.3 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.1 | 6.8 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.3 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.0 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 1.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 1.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.4 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.0 | 0.2 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
| 0.0 | 1.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 1.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.8 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 2.1 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 1.0 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 2.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 1.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.2 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.4 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.0 | 1.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.2 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.1 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.0 | 0.6 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 1.0 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 0.5 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.8 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 2.9 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 3.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 4.2 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 8.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 2.5 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.0 | 2.0 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 3.1 | GO:0051020 | GTPase binding(GO:0051020) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.2 | 18.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.2 | 15.4 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.2 | 3.1 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 11.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 5.3 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.1 | 3.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.1 | 1.0 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.1 | 2.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 5.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 2.3 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 3.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 2.9 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.0 | 4.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 3.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 2.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.3 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 2.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.4 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 2.6 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.9 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 0.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 1.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.5 | PID FGF PATHWAY | FGF signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 17.9 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.5 | 6.9 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.3 | 13.2 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.3 | 10.2 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 7.6 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.2 | 8.6 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.2 | 2.1 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.2 | 3.6 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 7.8 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 2.8 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.1 | 3.9 | REACTOME TCR SIGNALING | Genes involved in TCR signaling |
| 0.1 | 2.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 3.4 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 2.1 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 4.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 2.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.4 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 1.7 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 4.9 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.2 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 3.6 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 1.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.8 | REACTOME IL 3 5 AND GM CSF SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
| 0.0 | 1.3 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 1.1 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 5.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.9 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 1.5 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 1.0 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.0 | 0.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.6 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.0 | 0.7 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.5 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 2.3 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 1.1 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |