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Illumina Body Map 2: averaged replicates

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Results for PDX1

Z-value: 1.87

Motif logo

Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
ENSG00000139515.5 PDX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_28494168-0.106.0e-01Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_32157947 7.57 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr13_-_46716969 6.56 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_36245561 5.85 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_75080883 5.30 ENST00000567571.1
CSK
c-src tyrosine kinase
chr7_+_50348268 4.87 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_198607801 4.76 ENST00000367379.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_45269251 4.36 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr3_+_108541608 4.35 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr3_-_39321512 4.27 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr3_+_108541545 4.26 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr1_+_198608292 4.00 ENST00000418674.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_+_198608146 3.89 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr14_+_22564294 3.67 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr11_-_118083600 3.60 ENST00000524477.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr18_-_30353025 3.59 ENST00000359358.4
KLHL14
kelch-like family member 14
chr15_+_58430368 3.57 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr4_-_155533787 3.56 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr8_+_32579341 3.54 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr14_+_100485712 3.50 ENST00000544450.2
EVL
Enah/Vasp-like
chr8_+_32579321 3.48 ENST00000522402.1
NRG1
neuregulin 1
chr6_-_25042231 3.45 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr15_-_55563072 3.40 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55562479 3.37 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_+_58430567 3.37 ENST00000536493.1
AQP9
aquaporin 9
chr15_-_55562451 3.31 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr14_+_22554680 3.31 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chrX_+_123097014 3.25 ENST00000394478.1
STAG2
stromal antigen 2
chr8_+_32579271 3.16 ENST00000518084.1
NRG1
neuregulin 1
chr5_+_156712372 3.12 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr15_-_55562582 3.10 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr14_+_52313833 3.07 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr7_+_37723336 2.99 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr14_+_61654271 2.86 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr12_+_56325812 2.83 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr14_-_69261310 2.82 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr5_+_173930676 2.71 ENST00000504512.1
RP11-267A15.1
RP11-267A15.1
chr6_-_154568815 2.68 ENST00000519344.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr11_+_4510109 2.66 ENST00000307632.3
OR52K1
olfactory receptor, family 52, subfamily K, member 1
chr1_+_101003687 2.63 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr14_+_72052983 2.60 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chrX_-_20236970 2.57 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr5_+_173930710 2.51 ENST00000511707.1
RP11-267A15.1
RP11-267A15.1
chr12_+_107712173 2.47 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chr2_-_145188137 2.36 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr11_+_35222629 2.25 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr18_+_57567180 2.24 ENST00000316660.6
ENST00000269518.9
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr7_+_129015484 2.22 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr2_-_145277569 2.22 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr6_-_9933500 2.20 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr20_-_31124186 2.20 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr14_-_36988882 2.18 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chrX_-_20237059 2.15 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_+_91416092 2.14 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr12_+_56325231 2.13 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr5_+_66300464 2.12 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr13_-_41593425 2.12 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_-_27467418 2.10 ENST00000528564.1
MYO18A
myosin XVIIIA
chr6_-_154568551 2.09 ENST00000519190.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr16_+_53133070 2.09 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr13_+_78315528 2.06 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr6_+_130339710 2.06 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr10_-_48416849 2.05 ENST00000249598.1
GDF2
growth differentiation factor 2
chr13_+_78315466 2.03 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr3_-_57233966 2.00 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr11_-_85430356 2.00 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr7_-_115670792 1.90 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr21_+_30672433 1.89 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_-_81399329 1.89 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_116866773 1.86 ENST00000368602.3
TRAPPC3L
trafficking protein particle complex 3-like
chr14_+_22987424 1.75 ENST00000390511.1
TRAJ26
T cell receptor alpha joining 26
chr9_+_136501478 1.74 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr4_-_123377880 1.74 ENST00000226730.4
IL2
interleukin 2
chr8_+_9953214 1.68 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr7_-_115670804 1.66 ENST00000320239.7
TFEC
transcription factor EC
chr21_-_15918618 1.66 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr2_-_8715616 1.66 ENST00000418358.1
AC011747.3
AC011747.3
chr7_-_81399355 1.66 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_-_116833500 1.64 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr7_-_81399411 1.63 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr8_+_9953061 1.63 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr7_+_129015671 1.58 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_-_81399438 1.57 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr18_-_44181442 1.55 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chr11_-_85430204 1.53 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr12_+_50144381 1.52 ENST00000552370.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr12_+_28410128 1.50 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr5_-_140998616 1.49 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr11_-_85430088 1.48 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr14_+_22985251 1.48 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr11_-_85430163 1.47 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr7_-_92777606 1.46 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr2_+_45168875 1.46 ENST00000260653.3
SIX3
SIX homeobox 3
chr5_-_76935513 1.45 ENST00000306422.3
OTP
orthopedia homeobox
chr14_+_22992573 1.44 ENST00000390516.1
TRAJ21
T cell receptor alpha joining 21
chrX_-_19817869 1.44 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_141445333 1.43 ENST00000507667.1
ELMOD2
ELMO/CED-12 domain containing 2
chr9_-_123639445 1.42 ENST00000312189.6
PHF19
PHD finger protein 19
chr2_+_87769459 1.39 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr17_-_27418537 1.38 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr2_+_234959376 1.34 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr4_-_116034979 1.32 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr12_+_47610315 1.32 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr5_+_135394840 1.30 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr17_-_57229155 1.30 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr2_-_112237835 1.29 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr10_+_11047259 1.28 ENST00000379261.4
ENST00000416382.2
CELF2
CUGBP, Elav-like family member 2
chr18_-_46784778 1.26 ENST00000582399.1
DYM
dymeclin
chr10_+_114710425 1.26 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_61697862 1.26 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr5_-_134735568 1.26 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr21_+_30673091 1.24 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_-_69390209 1.23 ENST00000563634.1
RP11-343C2.9
Uncharacterized protein
chr15_-_98836406 1.22 ENST00000560360.1
CTD-2544M6.1
CTD-2544M6.1
chr8_-_42234745 1.21 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chrX_+_591524 1.21 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr18_-_53019208 1.20 ENST00000562607.1
TCF4
transcription factor 4
chr5_+_137722255 1.19 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr5_-_142780280 1.17 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_114710211 1.17 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_-_1709845 1.17 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr12_-_103344615 1.16 ENST00000546844.1
PAH
phenylalanine hydroxylase
chrX_-_110655306 1.16 ENST00000371993.2
DCX
doublecortin
chr1_+_28586006 1.15 ENST00000253063.3
SESN2
sestrin 2
chr4_-_41884620 1.15 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr17_-_6983594 1.14 ENST00000571664.1
ENST00000254868.4
CLEC10A
C-type lectin domain family 10, member A
chr12_-_53729525 1.13 ENST00000303846.3
SP7
Sp7 transcription factor
chr5_-_140998481 1.13 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr14_+_39944025 1.13 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr1_-_1710229 1.13 ENST00000341991.3
NADK
NAD kinase
chr18_+_3447572 1.12 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr1_-_182641367 1.08 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr16_-_30457048 1.08 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr4_+_66536248 1.08 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr2_+_90060377 1.07 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_-_53730147 1.06 ENST00000536324.2
SP7
Sp7 transcription factor
chr5_-_54988448 1.06 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr13_-_46626820 1.04 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr11_+_115498761 1.03 ENST00000424313.2
AP000997.1
AP000997.1
chr17_-_40337470 1.03 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_-_39979576 1.02 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chrX_-_21676442 1.01 ENST00000379499.2
KLHL34
kelch-like family member 34
chr17_-_6983550 1.00 ENST00000576617.1
ENST00000416562.2
CLEC10A
C-type lectin domain family 10, member A
chr21_-_32253874 1.00 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr20_+_42523336 1.00 ENST00000428529.1
RP5-1030M6.3
RP5-1030M6.3
chr20_+_11008408 0.99 ENST00000378252.1
C20orf187
chromosome 20 open reading frame 187
chr1_-_68698197 0.97 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr17_+_73452545 0.97 ENST00000314256.7
KIAA0195
KIAA0195
chr1_-_151965048 0.97 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr2_+_48541776 0.97 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr12_-_54813229 0.95 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_21625486 0.95 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr20_+_30697298 0.92 ENST00000398022.2
TM9SF4
transmembrane 9 superfamily protein member 4
chr17_-_39165366 0.92 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr6_+_49467671 0.91 ENST00000371197.4
ENST00000545705.1
GLYATL3
glycine-N-acyltransferase-like 3
chr20_+_62795827 0.90 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr3_-_131756559 0.90 ENST00000505957.1
CPNE4
copine IV
chr18_+_32558380 0.90 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr4_-_119759795 0.90 ENST00000419654.2
SEC24D
SEC24 family member D
chr13_-_99667960 0.90 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr1_+_159272111 0.90 ENST00000368114.1
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr7_-_81399287 0.89 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr19_+_50016610 0.88 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr17_+_73539339 0.86 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr15_+_34260921 0.86 ENST00000560035.1
CHRM5
cholinergic receptor, muscarinic 5
chr19_-_7698599 0.85 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr12_+_15699286 0.84 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_+_84609944 0.83 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr17_-_9929581 0.82 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr12_+_42725554 0.82 ENST00000546750.1
ENST00000547847.1
PPHLN1
periphilin 1
chr9_+_135457530 0.81 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr12_-_56321649 0.79 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chr1_+_36621174 0.79 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr1_+_66796401 0.78 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr14_-_95236551 0.78 ENST00000238558.3
GSC
goosecoid homeobox
chr14_-_57272366 0.78 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr6_+_150920999 0.77 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr4_+_105828492 0.77 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr16_-_18066399 0.76 ENST00000569048.1
CTA-481E9.4
CTA-481E9.4
chr20_+_43538756 0.75 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr9_-_123639304 0.75 ENST00000436309.1
PHF19
PHD finger protein 19
chr14_-_78083112 0.75 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr18_+_59000815 0.72 ENST00000262717.4
CDH20
cadherin 20, type 2
chr8_-_9761693 0.71 ENST00000521863.1
LINC00599
long intergenic non-protein coding RNA 599
chr4_+_169013666 0.70 ENST00000359299.3
ANXA10
annexin A10
chr1_-_151431647 0.70 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr5_-_141249154 0.69 ENST00000357517.5
ENST00000536585.1
PCDH1
protocadherin 1
chr15_+_69854027 0.69 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr2_-_89459813 0.69 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr5_-_134871639 0.69 ENST00000314744.4
NEUROG1
neurogenin 1
chr6_-_111136513 0.68 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr7_+_1272522 0.67 ENST00000316333.8
UNCX
UNC homeobox
chrX_-_133931164 0.67 ENST00000370790.1
ENST00000298090.6
FAM122B
family with sequence similarity 122B
chr12_-_53730126 0.67 ENST00000537210.2
SP7
Sp7 transcription factor
chr14_+_22947861 0.65 ENST00000390482.1
TRAJ57
T cell receptor alpha joining 57
chr1_+_28261533 0.64 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_-_182640988 0.64 ENST00000367556.1
RGS8
regulator of G-protein signaling 8
chr1_-_151431674 0.64 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr20_+_43538692 0.63 ENST00000217074.4
ENST00000255136.3
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr13_-_67802549 0.63 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr15_-_100882191 0.63 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.7 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
1.9 13.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.4 4.3 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.2 6.9 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.0 10.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
1.0 8.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 1.5 GO:0009946 proximal/distal axis specification(GO:0009946)
0.7 2.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.7 5.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.7 2.6 GO:0061743 motor learning(GO:0061743)
0.6 3.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.6 7.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 2.8 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.5 2.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.5 4.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.5 3.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 6.5 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.4 1.3 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.4 1.6 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.9 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.4 1.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.3 2.4 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 0.9 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.3 0.9 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.3 0.9 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.3 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 0.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 2.9 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 0.8 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.3 6.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 3.3 GO:0030091 protein repair(GO:0030091)
0.3 2.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 1.7 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.2 4.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.2 3.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 3.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 3.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.5 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 0.6 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 4.8 GO:0015671 oxygen transport(GO:0015671)
0.2 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.2 0.5 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 1.7 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 7.6 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 3.6 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.2 5.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 1.0 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 2.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 2.0 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 2.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.1 2.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 5.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 2.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 2.3 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.5 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 3.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.8 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 1.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.2 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.7 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 1.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 1.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 2.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 1.0 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.9 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.2 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.8 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.1 0.3 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.5 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.0 GO:0001765 membrane raft assembly(GO:0001765)
0.1 0.3 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 1.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 1.9 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 1.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 2.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.6 GO:0030900 forebrain development(GO:0030900)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 5.1 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 2.7 GO:2000738 positive regulation of stem cell differentiation(GO:2000738)
0.0 1.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 1.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.6 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.7 GO:0050790 regulation of catalytic activity(GO:0050790)
0.0 0.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 3.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.8 GO:0030901 midbrain development(GO:0030901)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.0 1.3 GO:0046849 bone remodeling(GO:0046849)
0.0 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 1.9 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 1.3 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 2.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 4.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.3 3.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 8.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 3.5 GO:0030008 TRAPP complex(GO:0030008)
0.2 10.2 GO:0030673 axolemma(GO:0030673)
0.2 6.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.3 GO:0001740 Barr body(GO:0001740)
0.2 6.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 7.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.5 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.7 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 7.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.8 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 12.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 13.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.5 GO:0016020 membrane(GO:0016020)
0.0 1.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 1.2 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.8 GO:0045095 keratin filament(GO:0045095)
0.0 4.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 4.0 GO:0043197 dendritic spine(GO:0043197)
0.0 1.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.6 GO:0005605 basal lamina(GO:0005605)
0.0 1.3 GO:0005604 basement membrane(GO:0005604)
0.0 4.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.4 6.9 GO:0015254 glycerol channel activity(GO:0015254)
0.8 10.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.6 3.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 3.8 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.4 2.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 13.2 GO:0031489 myosin V binding(GO:0031489)
0.4 1.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.3 13.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 8.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2 6.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 1.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.7 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.2 4.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 1.0 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 1.8 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.2 1.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 3.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 1.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 5.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 5.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 1.2 GO:0070728 leucine binding(GO:0070728)
0.2 2.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 3.5 GO:0005522 profilin binding(GO:0005522)
0.2 3.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 3.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.6 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 1.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 2.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 6.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 1.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 4.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 5.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 2.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 6.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.1 0.3 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 2.1 GO:0043531 ADP binding(GO:0043531)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 2.9 GO:0003774 motor activity(GO:0003774)
0.0 3.1 GO:0004386 helicase activity(GO:0004386)
0.0 4.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 8.7 GO:0003682 chromatin binding(GO:0003682)
0.0 2.5 GO:0044325 ion channel binding(GO:0044325)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 3.1 GO:0051020 GTPase binding(GO:0051020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 18.6 PID ARF6 PATHWAY Arf6 signaling events
0.2 15.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 3.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 11.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 5.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 3.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 5.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 3.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 2.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 4.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 17.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 6.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 13.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 10.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 7.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 8.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 2.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 7.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 2.8 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.9 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.1 2.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 4.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 5.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 1.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds