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Illumina Body Map 2: averaged replicates

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Results for POU1F1

Z-value: 2.16

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Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
POU1F1
ENSG00000064835.6 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325612_873256540.411.9e-02Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_101417919 3.62 ENST00000561338.1
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_+_78359999 3.60 ENST00000550503.1
NAV3
neuron navigator 3
chr21_-_43735628 3.54 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr21_-_15583165 3.37 ENST00000536861.1
LIPI
lipase, member I
chr12_+_26164645 3.29 ENST00000542004.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr14_+_101295638 3.28 ENST00000523671.2
MEG3
maternally expressed 3 (non-protein coding)
chr1_+_77333117 3.28 ENST00000477717.1
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr15_-_56757329 3.23 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr4_-_118006697 3.14 ENST00000310754.4
TRAM1L1
translocation associated membrane protein 1-like 1
chr10_-_13043697 3.05 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr5_+_140588269 2.90 ENST00000541609.1
ENST00000239450.2
PCDHB12
protocadherin beta 12
chrX_-_102531717 2.88 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chrX_-_55057403 2.88 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2
aminolevulinate, delta-, synthase 2
chr8_+_98900132 2.87 ENST00000520016.1
MATN2
matrilin 2
chr4_+_119809984 2.80 ENST00000307142.4
ENST00000448416.2
ENST00000429713.2
SYNPO2
synaptopodin 2
chr3_+_28390637 2.80 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr17_-_67224812 2.74 ENST00000423818.2
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr7_+_134528635 2.73 ENST00000445569.2
CALD1
caldesmon 1
chr10_+_53806501 2.65 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr1_+_87012753 2.63 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr5_+_140762268 2.56 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr4_+_119810134 2.54 ENST00000434046.2
SYNPO2
synaptopodin 2
chr8_+_30244580 2.53 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr6_-_49712147 2.50 ENST00000433368.2
ENST00000354620.4
CRISP3
cysteine-rich secretory protein 3
chr7_-_16872932 2.46 ENST00000419572.2
ENST00000412973.1
AGR2
anterior gradient 2
chr8_-_38008783 2.45 ENST00000276449.4
STAR
steroidogenic acute regulatory protein
chr6_-_49712123 2.44 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr14_-_80697396 2.42 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr6_-_76072719 2.41 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr11_+_12399071 2.39 ENST00000539723.1
ENST00000550549.1
PARVA
parvin, alpha
chr2_-_166930131 2.38 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr18_-_64271363 2.36 ENST00000262150.2
CDH19
cadherin 19, type 2
chr1_+_43613566 2.35 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr6_-_49712072 2.35 ENST00000423399.2
CRISP3
cysteine-rich secretory protein 3
chr6_-_52859046 2.34 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
GSTA4
glutathione S-transferase alpha 4
chr8_+_70404996 2.33 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr2_+_232135245 2.28 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr6_-_49712091 2.28 ENST00000371159.4
CRISP3
cysteine-rich secretory protein 3
chr5_+_140552218 2.26 ENST00000231137.3
PCDHB7
protocadherin beta 7
chr5_+_140593509 2.25 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr12_-_15038779 2.23 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr1_+_87012922 2.23 ENST00000263723.5
CLCA4
chloride channel accessory 4
chr3_+_16216137 2.22 ENST00000339732.5
GALNT15
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr8_-_101117847 2.21 ENST00000523287.1
ENST00000519092.1
RGS22
regulator of G-protein signaling 22
chr1_+_43613612 2.21 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr12_+_26348429 2.20 ENST00000242729.2
SSPN
sarcospan
chr4_-_46911248 2.18 ENST00000355591.3
ENST00000505102.1
COX7B2
cytochrome c oxidase subunit VIIb2
chr12_-_7596735 2.17 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr4_-_138453606 2.16 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr9_-_28670283 2.14 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_-_16675930 2.09 ENST00000503178.2
LDB2
LIM domain binding 2
chr17_+_12569306 2.08 ENST00000425538.1
MYOCD
myocardin
chr22_-_40289759 2.04 ENST00000325157.6
ENTHD1
ENTH domain containing 1
chr11_-_128894053 2.00 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr11_+_101918153 2.00 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr17_-_57158523 1.95 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr5_+_125798031 1.95 ENST00000502348.1
GRAMD3
GRAM domain containing 3
chrX_-_73061339 1.95 ENST00000602863.1
XIST
X inactive specific transcript (non-protein coding)
chr15_+_84115868 1.92 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr1_+_15668240 1.92 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr1_-_160924589 1.91 ENST00000368029.3
ITLN2
intelectin 2
chr3_-_20053741 1.88 ENST00000389050.4
PP2D1
protein phosphatase 2C-like domain containing 1
chr4_-_122854612 1.87 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr3_-_160823158 1.85 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr11_-_26593649 1.85 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr3_+_132843652 1.84 ENST00000508711.1
TMEM108
transmembrane protein 108
chr19_-_36001113 1.83 ENST00000434389.1
DMKN
dermokine
chr12_-_71148413 1.83 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_112938803 1.81 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr12_-_86650154 1.78 ENST00000552435.2
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr9_+_95997205 1.73 ENST00000411624.1
WNK2
WNK lysine deficient protein kinase 2
chr3_-_160823040 1.73 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr14_-_54425475 1.73 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr8_-_124741451 1.70 ENST00000520519.1
ANXA13
annexin A13
chr8_+_133909919 1.69 ENST00000518505.1
TG
thyroglobulin
chr10_+_18549645 1.68 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_+_26348246 1.68 ENST00000422622.2
SSPN
sarcospan
chr5_+_119867159 1.68 ENST00000505123.1
PRR16
proline rich 16
chr5_+_173472607 1.67 ENST00000303177.3
ENST00000519867.1
NSG2
Neuron-specific protein family member 2
chr11_-_107729504 1.66 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr3_-_145940126 1.66 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr6_-_110501200 1.65 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr1_-_91813006 1.64 ENST00000430465.1
HFM1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr12_-_86650045 1.64 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_71148357 1.63 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr4_-_186570679 1.62 ENST00000451974.1
SORBS2
sorbin and SH3 domain containing 2
chr19_-_22193706 1.62 ENST00000597040.1
ZNF208
zinc finger protein 208
chr4_-_138453559 1.62 ENST00000511115.1
PCDH18
protocadherin 18
chr11_-_107729287 1.61 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chrX_-_13835147 1.60 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr1_+_8378140 1.59 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr4_+_9446156 1.58 ENST00000334879.1
DEFB131
defensin, beta 131
chr18_-_59274139 1.57 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr18_+_21269404 1.56 ENST00000313654.9
LAMA3
laminin, alpha 3
chr11_-_107729887 1.55 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_+_81771806 1.54 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr4_-_159956333 1.53 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr21_-_27423339 1.53 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr11_-_26593677 1.50 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr12_+_131438496 1.50 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr18_+_616672 1.47 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr6_-_110501126 1.46 ENST00000368938.1
WASF1
WAS protein family, member 1
chr9_+_111624577 1.45 ENST00000333999.3
ACTL7A
actin-like 7A
chr2_+_242913327 1.45 ENST00000426962.1
AC093642.3
AC093642.3
chr11_-_102651343 1.44 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chrX_+_154113317 1.43 ENST00000354461.2
H2AFB1
H2A histone family, member B1
chrX_-_142605301 1.42 ENST00000370503.2
SPANXN3
SPANX family, member N3
chr17_+_12569472 1.41 ENST00000343344.4
MYOCD
myocardin
chr18_+_21269556 1.40 ENST00000399516.3
LAMA3
laminin, alpha 3
chr21_-_30047095 1.40 ENST00000452028.1
ENST00000433310.2
AF131217.1
AF131217.1
chrX_-_11308598 1.39 ENST00000380717.3
ARHGAP6
Rho GTPase activating protein 6
chr2_+_210517895 1.36 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr11_+_4664650 1.35 ENST00000396952.5
OR51E1
olfactory receptor, family 51, subfamily E, member 1
chr2_+_149974684 1.34 ENST00000450639.1
LYPD6B
LY6/PLAUR domain containing 6B
chr13_+_24144796 1.34 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr22_-_32767017 1.34 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr12_-_22063787 1.32 ENST00000544039.1
ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_-_125930929 1.30 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr11_+_122753391 1.28 ENST00000307257.6
ENST00000227349.2
C11orf63
chromosome 11 open reading frame 63
chr1_-_205391178 1.28 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr2_+_11696464 1.28 ENST00000234142.5
GREB1
growth regulation by estrogen in breast cancer 1
chr12_-_85430024 1.28 ENST00000547836.1
ENST00000532498.2
TSPAN19
tetraspanin 19
chr18_-_73967160 1.27 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr7_-_84122033 1.26 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_145940214 1.24 ENST00000481701.1
PLSCR4
phospholipid scramblase 4
chr3_+_169539710 1.23 ENST00000340806.6
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chr14_-_25479811 1.21 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr7_-_86688990 1.18 ENST00000450689.2
KIAA1324L
KIAA1324-like
chr4_-_46126093 1.18 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr6_-_26235206 1.16 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr19_+_49199209 1.16 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr17_+_1674982 1.15 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_-_13517565 1.15 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr4_+_3344141 1.15 ENST00000306648.7
RGS12
regulator of G-protein signaling 12
chr14_+_20187174 1.15 ENST00000557414.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr21_-_39705323 1.14 ENST00000436845.1
AP001422.3
AP001422.3
chrX_+_153533275 1.14 ENST00000426989.1
ENST00000426203.1
ENST00000369912.2
TKTL1
transketolase-like 1
chr22_+_31460091 1.14 ENST00000432777.1
ENST00000422839.1
SMTN
smoothelin
chr4_+_169552748 1.14 ENST00000504519.1
ENST00000512127.1
PALLD
palladin, cytoskeletal associated protein
chr5_+_81575281 1.13 ENST00000380167.4
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr16_-_67217844 1.12 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L
KIAA0895-like
chr19_+_54466179 1.11 ENST00000270458.2
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr12_-_86650077 1.11 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr6_-_52859968 1.09 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr5_-_111754948 1.08 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr10_+_127585093 1.07 ENST00000368695.1
ENST00000368693.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr11_-_4719072 1.06 ENST00000396950.3
ENST00000532598.1
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr20_-_29978383 1.06 ENST00000339144.3
ENST00000376321.3
DEFB119
defensin, beta 119
chrX_-_15288154 1.05 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ASB9
ankyrin repeat and SOCS box containing 9
chr4_+_96012614 1.04 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_-_102941596 1.04 ENST00000441076.2
ENST00000422355.1
ENST00000442614.1
ENST00000422154.2
ENST00000451301.1
MORF4L2
mortality factor 4 like 2
chrX_-_154689596 1.04 ENST00000369444.2
H2AFB3
H2A histone family, member B3
chr3_-_46759314 1.03 ENST00000315170.7
PRSS50
protease, serine, 50
chr2_-_190044480 1.03 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr9_-_34729457 1.03 ENST00000378788.3
FAM205A
family with sequence similarity 205, member A
chr21_-_22175341 1.02 ENST00000416768.1
ENST00000452561.1
ENST00000419299.1
ENST00000437238.1
LINC00320
long intergenic non-protein coding RNA 320
chr12_-_11150474 1.01 ENST00000538986.1
TAS2R20
taste receptor, type 2, member 20
chr1_+_197237352 1.01 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
CRB1
crumbs homolog 1 (Drosophila)
chrX_+_43515467 1.01 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr20_-_56647116 1.01 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
RP13-379L11.1
chr1_-_182921119 1.00 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr17_-_4938712 0.99 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr8_+_36641842 0.98 ENST00000523973.1
ENST00000399881.3
KCNU1
potassium channel, subfamily U, member 1
chr9_+_12693336 0.97 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr19_-_22193731 0.96 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
ZNF208
zinc finger protein 208
chr15_-_75748143 0.96 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr19_+_52873166 0.95 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
ZNF880
zinc finger protein 880
chr21_-_39705286 0.95 ENST00000414189.1
AP001422.3
AP001422.3
chr2_-_207078154 0.94 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr1_+_76251912 0.93 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr9_-_21482312 0.93 ENST00000448696.3
IFNE
interferon, epsilon
chrX_-_52827141 0.92 ENST00000375511.3
SPANXN5
SPANX family, member N5
chr1_-_152779104 0.91 ENST00000606576.1
ENST00000368768.1
LCE1C
late cornified envelope 1C
chr7_+_130126165 0.91 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr2_+_44001172 0.91 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr6_-_47445214 0.90 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr10_+_17270214 0.88 ENST00000544301.1
VIM
vimentin
chr17_-_38821373 0.88 ENST00000394052.3
KRT222
keratin 222
chr4_+_147145709 0.88 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr8_+_39972170 0.87 ENST00000521257.1
RP11-359E19.2
RP11-359E19.2
chr1_-_247921982 0.87 ENST00000408896.2
OR1C1
olfactory receptor, family 1, subfamily C, member 1
chr7_+_128349106 0.86 ENST00000485070.1
FAM71F1
family with sequence similarity 71, member F1
chr14_-_36990354 0.86 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr4_-_70518941 0.85 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr2_+_217732661 0.84 ENST00000451711.1
AC007557.3
AC007557.3
chr12_-_106480587 0.84 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr2_-_207078086 0.84 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr2_-_43266680 0.83 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
AC016735.2
chr3_+_38537960 0.82 ENST00000453767.1
EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr9_-_21351377 0.82 ENST00000380210.1
IFNA6
interferon, alpha 6
chr10_+_695888 0.81 ENST00000441152.2
PRR26
proline rich 26
chr22_+_43011247 0.81 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr4_-_139051839 0.81 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
LINC00616
long intergenic non-protein coding RNA 616
chr1_-_228613026 0.80 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr8_-_57233103 0.80 ENST00000303749.3
ENST00000522671.1
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr16_-_75734044 0.80 ENST00000398113.2
ENST00000538623.1
AC025287.1
Uncharacterized protein
chr12_+_131438443 0.78 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr7_+_12544025 0.78 ENST00000443874.1
ENST00000424453.1
AC005281.1
AC005281.1
chr2_-_27712583 0.77 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr16_+_16434185 0.76 ENST00000524823.2
AC138969.4
Protein PKD1P1

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0060166 olfactory pit development(GO:0060166)
0.9 3.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.7 3.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.6 2.5 GO:0018963 insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963)
0.5 1.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 3.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.5 1.9 GO:0032053 ciliary basal body organization(GO:0032053)
0.4 1.2 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 2.5 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.3 1.7 GO:0061216 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 2.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 5.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.3 2.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.3 1.3 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 1.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.3 1.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 1.5 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.3 1.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.3 1.8 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 1.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 1.9 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 6.9 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 0.7 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 1.7 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.2 1.0 GO:0032218 riboflavin transport(GO:0032218)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 2.7 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.2 4.0 GO:0070986 left/right axis specification(GO:0070986)
0.2 1.2 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.2 2.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 2.4 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2 1.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.2 1.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.1 1.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 2.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.4 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 1.7 GO:0015705 iodide transport(GO:0015705)
0.1 2.9 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.7 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 1.2 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 2.5 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.4 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:1903947 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 0.5 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 3.0 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 3.4 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 1.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.1 1.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 3.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.2 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 1.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.7 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.9 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.8 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 4.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.9 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.1 1.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.6 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 12.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 2.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 2.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 0.5 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 5.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.3 GO:1904468 negative regulation of tumor necrosis factor secretion(GO:1904468)
0.1 0.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.3 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.7 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.4 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:2000698 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.8 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.7 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.6 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.4 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 2.9 GO:0008347 glial cell migration(GO:0008347)
0.0 0.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.1 GO:2000397 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.9 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 1.0 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 4.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.4 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.7 GO:0051642 centrosome localization(GO:0051642)
0.0 2.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.0 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.8 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.3 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 5.9 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.8 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 1.0 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.4 GO:0097503 sialylation(GO:0097503)
0.0 1.3 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 1.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 2.4 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.4 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.4 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 6.1 GO:0006936 muscle contraction(GO:0006936)
0.0 1.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 3.5 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.3 3.0 GO:0005610 laminin-5 complex(GO:0005610)
0.3 0.8 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.7 GO:0030478 actin cap(GO:0030478)
0.2 3.1 GO:0031209 SCAR complex(GO:0031209)
0.2 1.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 2.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.5 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.4 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.1 1.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 2.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.4 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 1.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 4.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 8.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.2 GO:0000806 Y chromosome(GO:0000806)
0.1 0.3 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 3.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.7 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.6 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 1.0 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.7 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 9.6 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 3.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.0 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.9 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 14.4 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 6.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)
0.0 1.1 GO:0043234 protein complex(GO:0043234)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.5 2.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.5 4.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 3.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4 2.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 1.3 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 2.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.1 GO:0004802 transketolase activity(GO:0004802)
0.3 0.8 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 1.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 3.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 1.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 2.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 2.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.7 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.2 0.7 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.5 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 6.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.1 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 4.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 2.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 4.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 1.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.9 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 1.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.5 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.7 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.9 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 2.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 2.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.6 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 3.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 1.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 7.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 3.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 2.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.0 17.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 1.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0016248 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.7 PID BMP PATHWAY BMP receptor signaling
0.0 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 3.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 4.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 2.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 3.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 0.9 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 2.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 0.7 REACTOME OPSINS Genes involved in Opsins
0.0 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 2.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 5.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 3.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.8 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels