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Illumina Body Map 2: averaged replicates

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Results for POU2F1

Z-value: 2.64

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Transcription factors associated with POU2F1

Gene Symbol Gene ID Gene Info
ENSG00000143190.17 POU class 2 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F1hg19_v2_chr1_+_167298281_167298319-0.096.2e-01Click!

Activity profile of POU2F1 motif

Sorted Z-values of POU2F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_34391625 8.47 ENST00000004921.3
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr14_-_106453155 6.87 ENST00000390594.2
immunoglobulin heavy variable 1-2
chr14_-_106733624 6.69 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr2_-_238305397 6.62 ENST00000409809.1
collagen, type VI, alpha 3
chr14_-_106539557 6.09 ENST00000390599.2
immunoglobulin heavy variable 1-8
chr14_-_106967788 6.00 ENST00000390622.2
immunoglobulin heavy variable 1-46
chr21_+_10862622 5.87 ENST00000302092.5
ENST00000559480.1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_-_89545079 5.81 ENST00000468494.1
immunoglobulin kappa variable 2-30
chr2_+_89975669 5.61 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr2_-_89521942 5.57 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr2_+_89890533 5.54 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr15_-_22448819 5.52 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr14_-_106471723 5.24 ENST00000390595.2
immunoglobulin heavy variable 1-3
chr14_-_107078851 5.14 ENST00000390628.2
immunoglobulin heavy variable 1-58
chr14_-_106642049 5.13 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr12_-_111358372 4.92 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr22_+_23029188 4.84 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr22_+_23010756 4.79 ENST00000390304.2
immunoglobulin lambda variable 3-27
chr2_-_89459813 4.64 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr16_+_33629600 4.58 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr2_+_89196746 4.48 ENST00000390244.2
immunoglobulin kappa variable 5-2
chr14_-_107211459 4.32 ENST00000390636.2
immunoglobulin heavy variable 3-73
chr12_-_102874330 4.05 ENST00000307046.8
insulin-like growth factor 1 (somatomedin C)
chr14_-_106791536 4.00 ENST00000390613.2
immunoglobulin heavy variable 3-30
chr2_+_89999259 4.00 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr15_-_22473353 3.99 ENST00000557788.2
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr2_+_90060377 3.90 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr2_-_89292422 3.83 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr14_-_107283278 3.54 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr2_+_90458201 3.46 ENST00000603238.1
Uncharacterized protein
chr22_+_23089870 3.42 ENST00000390311.2
immunoglobulin lambda variable 3-16
chrX_+_15518923 3.26 ENST00000348343.6
BMX non-receptor tyrosine kinase
chr2_+_36923933 3.11 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
vitrin
chr11_-_101778665 2.93 ENST00000534527.1
angiopoietin-like 5
chr12_-_7245125 2.93 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr2_+_168043793 2.91 ENST00000409273.1
ENST00000409605.1
xin actin-binding repeat containing 2
chr9_-_13432977 2.83 ENST00000605459.1
RP11-536O18.2
chr12_-_7245152 2.80 ENST00000542220.2
complement component 1, r subcomponent
chr8_+_30244580 2.75 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr12_-_102874416 2.70 ENST00000392904.1
ENST00000337514.6
insulin-like growth factor 1 (somatomedin C)
chr12_-_7245018 2.67 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr2_+_36923830 2.65 ENST00000379242.3
ENST00000389975.3
vitrin
chr2_+_90108504 2.56 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr12_-_7245080 2.55 ENST00000541042.1
ENST00000540242.1
complement component 1, r subcomponent
chr12_-_102874378 2.50 ENST00000456098.1
insulin-like growth factor 1 (somatomedin C)
chr12_-_7596735 2.48 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163 molecule-like 1
chr1_-_160681593 2.45 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr2_+_36923901 2.45 ENST00000457137.2
vitrin
chr8_-_86290333 2.33 ENST00000521846.1
ENST00000523022.1
ENST00000524324.1
ENST00000519991.1
ENST00000520663.1
ENST00000517590.1
ENST00000522579.1
ENST00000522814.1
ENST00000522662.1
ENST00000523858.1
ENST00000519129.1
carbonic anhydrase I
chr13_-_38172863 2.23 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr4_+_70796784 2.13 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr6_+_135502501 2.12 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr3_+_157154578 2.10 ENST00000295927.3
pentraxin 3, long
chr13_-_40924439 2.00 ENST00000400432.3
RP11-172E9.2
chr17_-_66951474 1.96 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_91546926 1.91 ENST00000550758.1
decorin
chr8_-_101730061 1.89 ENST00000519100.1
poly(A) binding protein, cytoplasmic 1
chr3_-_111314230 1.87 ENST00000317012.4
zinc finger, BED-type containing 2
chr9_+_124088860 1.86 ENST00000373806.1
gelsolin
chr4_+_40194570 1.75 ENST00000507851.1
ras homolog family member H
chr4_-_110723194 1.73 ENST00000394635.3
complement factor I
chr17_-_66951382 1.69 ENST00000586539.1
ATP-binding cassette, sub-family A (ABC1), member 8
chr17_-_41910505 1.68 ENST00000398389.4
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr8_-_6837602 1.68 ENST00000382692.2
defensin, alpha 1
chr11_-_101000445 1.67 ENST00000534013.1
progesterone receptor
chr1_+_196621002 1.64 ENST00000367429.4
ENST00000439155.2
complement factor H
chr14_-_92247032 1.63 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr6_-_46922659 1.63 ENST00000265417.7
G protein-coupled receptor 116
chr11_-_128457446 1.63 ENST00000392668.4
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr1_-_89736434 1.63 ENST00000370459.3
guanylate binding protein 5
chr8_-_93107827 1.60 ENST00000520724.1
ENST00000518844.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_-_93107696 1.58 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_27849378 1.55 ENST00000310791.2
RAB15 effector protein
chr4_-_110723335 1.55 ENST00000394634.2
complement factor I
chr5_+_118668846 1.55 ENST00000513374.1
tumor necrosis factor, alpha-induced protein 8
chr8_-_93107855 1.51 ENST00000517919.1
ENST00000519847.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_176326333 1.51 ENST00000292432.5
hexokinase 3 (white cell)
chr14_+_22089953 1.50 ENST00000542354.1
T cell receptor alpha variable 1-1
chr9_+_112887772 1.49 ENST00000259318.7
A kinase (PRKA) anchor protein 2
chr4_-_152147579 1.47 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3 domain containing 19
chr4_-_110723134 1.47 ENST00000510800.1
ENST00000512148.1
complement factor I
chr3_-_145940214 1.47 ENST00000481701.1
phospholipid scramblase 4
chr22_-_37571089 1.46 ENST00000453962.1
ENST00000429622.1
ENST00000445595.1
interleukin 2 receptor, beta
chr2_+_204571198 1.43 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28 molecule
chr4_+_126315091 1.42 ENST00000335110.5
FAT atypical cadherin 4
chr14_-_21270995 1.41 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr7_+_20686946 1.41 ENST00000443026.2
ENST00000406935.1
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr1_+_104293028 1.40 ENST00000370079.3
amylase, alpha 1C (salivary)
chr1_-_25291475 1.40 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr6_+_135502466 1.40 ENST00000367814.4
v-myb avian myeloblastosis viral oncogene homolog
chr14_-_21270561 1.38 ENST00000412779.2
ribonuclease, RNase A family, 1 (pancreatic)
chr11_-_8892900 1.37 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
suppression of tumorigenicity 5
chr8_-_49833978 1.36 ENST00000020945.1
snail family zinc finger 2
chr18_+_3252206 1.33 ENST00000578562.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr11_-_107729887 1.32 ENST00000525815.1
solute carrier family 35, member F2
chr18_-_52989217 1.31 ENST00000570287.2
transcription factor 4
chr4_+_70861647 1.30 ENST00000246895.4
ENST00000381060.2
statherin
chr15_-_55541227 1.27 ENST00000566877.1
RAB27A, member RAS oncogene family
chr4_+_75230853 1.27 ENST00000244869.2
epiregulin
chr7_-_84121858 1.26 ENST00000448879.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_186570679 1.25 ENST00000451974.1
sorbin and SH3 domain containing 2
chr19_+_14693888 1.24 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
C-type lectin domain family 17, member A
chr7_-_14026063 1.23 ENST00000443608.1
ENST00000438956.1
ets variant 1
chr3_+_101546827 1.23 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr20_+_9146969 1.22 ENST00000416836.1
phospholipase C, beta 4
chr3_-_148939598 1.21 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr4_-_100065419 1.20 ENST00000504125.1
ENST00000505590.1
alcohol dehydrogenase 4 (class II), pi polypeptide
chr11_+_4673716 1.18 ENST00000530215.1
olfactory receptor, family 51, subfamily E, member 1
chr2_+_71205510 1.17 ENST00000272421.6
ENST00000441349.1
ENST00000457410.1
ankyrin repeat domain 53
chr18_+_61144160 1.16 ENST00000489441.1
ENST00000424602.1
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr14_+_22689792 1.13 ENST00000390462.1
T cell receptor alpha variable 35
chr7_-_14026123 1.13 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ets variant 1
chr3_-_145940126 1.11 ENST00000498625.1
phospholipid scramblase 4
chr6_-_123958141 1.10 ENST00000334268.4
triadin
chr1_+_104198640 1.08 ENST00000422549.1
amylase, alpha 1A (salivary)
chr4_-_120550146 1.08 ENST00000354960.3
phosphodiesterase 5A, cGMP-specific
chr4_+_120056939 1.07 ENST00000307128.5
myozenin 2
chr3_+_2553281 1.07 ENST00000434053.1
contactin 4
chrX_-_6146876 1.07 ENST00000381095.3
neuroligin 4, X-linked
chr13_+_24883703 1.06 ENST00000332018.4
C1q and tumor necrosis factor related protein 9
chr6_+_135502408 1.05 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
v-myb avian myeloblastosis viral oncogene homolog
chr7_-_142207004 1.03 ENST00000426318.2
T cell receptor beta variable 10-2
chr2_+_204571375 1.02 ENST00000374478.4
CD28 molecule
chr17_+_38171681 1.01 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr2_+_169659121 1.00 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
nitric oxide synthase trafficking
chr11_-_58343319 0.99 ENST00000395074.2
leupaxin
chr3_+_136676851 0.99 ENST00000309741.5
interleukin 20 receptor beta
chr11_+_3011093 0.99 ENST00000332881.2
HCG1782999; PRO0943; Uncharacterized protein
chr6_-_123958051 0.98 ENST00000546248.1
triadin
chr2_-_197226875 0.97 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr2_+_103035102 0.95 ENST00000264260.2
interleukin 18 receptor accessory protein
chr2_+_169658928 0.91 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chr1_+_62439037 0.89 ENST00000545929.1
InaD-like (Drosophila)
chr6_+_116832789 0.87 ENST00000368599.3
family with sequence similarity 26, member E
chr17_+_38171614 0.86 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr6_-_123957942 0.85 ENST00000398178.3
triadin
chr6_-_123958111 0.84 ENST00000542443.1
triadin
chr2_+_71205742 0.82 ENST00000360589.3
ankyrin repeat domain 53
chr3_+_136676707 0.82 ENST00000329582.4
interleukin 20 receptor beta
chr1_-_169703203 0.82 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr1_+_198608292 0.81 ENST00000418674.1
protein tyrosine phosphatase, receptor type, C
chr3_-_165555200 0.81 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr3_-_46069223 0.80 ENST00000309285.3
chemokine (C motif) receptor 1
chr4_-_144940477 0.80 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
glycophorin B (MNS blood group)
chr6_-_27782548 0.78 ENST00000333151.3
histone cluster 1, H2aj
chr5_-_98262240 0.76 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr9_-_140196703 0.75 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr3_-_58200398 0.75 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
deoxyribonuclease I-like 3
chrX_+_114827851 0.72 ENST00000539310.1
plastin 3
chr1_+_104159999 0.71 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr14_+_21249200 0.70 ENST00000304677.2
ribonuclease, RNase A family, k6
chr3_+_187896331 0.70 ENST00000392468.2
Uncharacterized protein
chr17_-_41623716 0.70 ENST00000319349.5
ets variant 4
chr8_+_18067602 0.69 ENST00000307719.4
ENST00000545197.1
ENST00000539092.1
ENST00000541942.1
ENST00000518029.1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr11_-_107729287 0.69 ENST00000375682.4
solute carrier family 35, member F2
chr4_+_68424434 0.68 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr11_-_110561721 0.68 ENST00000357139.3
Rho GTPase activating protein 20
chr4_+_40194609 0.67 ENST00000508513.1
ras homolog family member H
chr3_-_149293990 0.67 ENST00000472417.1
WW domain containing transcription regulator 1
chr11_-_107729504 0.67 ENST00000265836.7
solute carrier family 35, member F2
chr2_+_173292059 0.65 ENST00000412899.1
ENST00000409532.1
integrin, alpha 6
chr12_-_72057571 0.65 ENST00000548100.1
zinc finger, C3H1-type containing
chr3_+_182983126 0.64 ENST00000481531.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_-_146781153 0.64 ENST00000520473.1
dihydropyrimidinase-like 3
chr10_+_118187379 0.63 ENST00000369230.3
pancreatic lipase-related protein 3
chr8_-_93107726 0.62 ENST00000520974.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_+_39903185 0.62 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_+_14294187 0.61 ENST00000573051.1
MKL/myocardin-like 2
chr2_+_102615416 0.57 ENST00000393414.2
interleukin 1 receptor, type II
chr15_-_63448973 0.57 ENST00000462430.1
ribosomal protein S27-like
chr12_+_105380073 0.54 ENST00000552951.1
ENST00000280749.5
chromosome 12 open reading frame 45
chrX_-_99665262 0.53 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr9_+_116638562 0.53 ENST00000374126.5
ENST00000288466.7
zinc finger protein 618
chr8_-_117768023 0.53 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
eukaryotic translation initiation factor 3, subunit H
chr4_-_177190364 0.52 ENST00000296525.3
ankyrin repeat and SOCS box containing 5
chr14_-_104408645 0.50 ENST00000557640.1
retinal degeneration 3-like
chr10_+_126630692 0.50 ENST00000359653.4
zinc finger, RAN-binding domain containing 1
chrY_+_15418467 0.50 ENST00000595988.1
Uncharacterized protein
chr14_+_29299437 0.48 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1
chr3_+_133292574 0.48 ENST00000264993.3
CDV3 homolog (mouse)
chr10_+_79793518 0.47 ENST00000440692.1
ENST00000435275.1
ENST00000372360.3
ENST00000360830.4
ribosomal protein S24
chr12_-_106480587 0.47 ENST00000548902.1
NUAK family, SNF1-like kinase, 1
chr6_+_127898312 0.44 ENST00000329722.7
chromosome 6 open reading frame 58
chr1_+_44398943 0.43 ENST00000372359.5
ENST00000414809.3
artemin
chr17_-_7387524 0.42 ENST00000311403.4
zinc finger and BTB domain containing 4
chr9_-_39239171 0.41 ENST00000358144.2
contactin associated protein-like 3
chr19_+_30156351 0.39 ENST00000592810.1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr9_+_116638630 0.38 ENST00000452710.1
ENST00000374124.4
zinc finger protein 618
chr2_-_145275211 0.37 ENST00000462355.1
zinc finger E-box binding homeobox 2
chr12_+_16500599 0.37 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr11_-_58980342 0.37 ENST00000361050.3
macrophage expressed 1
chr3_-_74570291 0.37 ENST00000263665.6
contactin 3 (plasmacytoma associated)
chr12_-_10601963 0.36 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chr16_-_18462221 0.35 ENST00000528301.1
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr7_+_48211048 0.35 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr10_-_116286563 0.34 ENST00000369253.2
actin binding LIM protein 1
chr4_+_169575875 0.33 ENST00000503457.1
palladin, cytoskeletal associated protein
chr10_-_116286656 0.32 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
actin binding LIM protein 1
chr9_-_123812542 0.32 ENST00000223642.1
complement component 5
chr6_+_55192267 0.32 ENST00000340465.2
GDNF family receptor alpha like

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.2 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.5 4.6 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.9 3.8 GO:1901846 positive regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901846)
0.7 113.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.5 1.6 GO:0072616 interleukin-18 secretion(GO:0072616)
0.5 1.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 1.8 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.4 4.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 1.3 GO:0042700 luteinizing hormone signaling pathway(GO:0042700)
0.4 1.7 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.4 1.7 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.4 1.9 GO:0044858 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.4 2.2 GO:0032571 response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.3 5.1 GO:0042908 xenobiotic transport(GO:0042908)
0.3 1.3 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3 2.1 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.3 1.4 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.3 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 1.5 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 0.7 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.2 1.6 GO:0030578 PML body organization(GO:0030578)
0.2 3.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.2 1.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 2.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.2 2.4 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.2 0.8 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 1.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.6 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 3.8 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 1.9 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 7.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.7 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 1.0 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 2.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 3.4 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 1.3 GO:0046541 saliva secretion(GO:0046541)
0.1 0.4 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.1 GO:0003360 brainstem development(GO:0003360)
0.1 0.7 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 14.6 GO:0002377 immunoglobulin production(GO:0002377)
0.1 6.6 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.8 GO:0050900 leukocyte migration(GO:0050900)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 3.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.0 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.7 GO:0010668 ectodermal cell differentiation(GO:0010668) nail development(GO:0035878)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.7 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 1.5 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.0 1.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 1.7 GO:0046710 GDP metabolic process(GO:0046710)
0.0 2.9 GO:0003281 ventricular septum development(GO:0003281)
0.0 6.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.6 GO:0033572 transferrin transport(GO:0033572)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.2 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 1.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 2.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 1.9 GO:0050999 regulation of nitric-oxide synthase activity(GO:0050999)
0.0 1.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0016042 lipid catabolic process(GO:0016042)
0.0 1.6 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 9.1 GO:0002250 adaptive immune response(GO:0002250)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 2.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.0 GO:1901661 quinone metabolic process(GO:1901661)
0.0 1.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.4 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0051145 smooth muscle cell differentiation(GO:0051145)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 9.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.7 40.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.6 8.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 3.8 GO:0030314 junctional membrane complex(GO:0030314)
0.3 4.9 GO:0097512 cardiac myofibril(GO:0097512)
0.3 8.2 GO:0005614 interstitial matrix(GO:0005614)
0.2 1.6 GO:0036128 CatSper complex(GO:0036128)
0.2 36.7 GO:0072562 blood microparticle(GO:0072562)
0.2 0.7 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 2.7 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.0 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.4 GO:0001772 immunological synapse(GO:0001772)
0.1 1.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 3.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 10.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.1 GO:0030018 Z disc(GO:0030018)
0.0 2.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 28.9 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 40.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 1.3 GO:0046848 hydroxyapatite binding(GO:0046848)
0.4 2.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.4 2.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 5.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.4 79.8 GO:0003823 antigen binding(GO:0003823)
0.4 1.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.0 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.3 4.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 1.8 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.5 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 2.3 GO:0004064 arylesterase activity(GO:0004064)
0.3 2.1 GO:0046790 virion binding(GO:0046790)
0.2 4.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.8 GO:0033265 choline binding(GO:0033265)
0.2 8.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.2 1.1 GO:0051373 FATZ binding(GO:0051373)
0.2 1.2 GO:0042806 fucose binding(GO:0042806)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.9 GO:0045159 myosin II binding(GO:0045159)
0.2 1.5 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 8.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 2.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 1.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 2.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 1.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.6 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 1.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 5.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 7.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.3 GO:0031489 myosin V binding(GO:0031489)
0.0 2.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 9.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 8.5 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 2.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.7 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 2.3 GO:0008083 growth factor activity(GO:0008083)
0.0 5.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 8.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 6.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 6.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.9 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.3 PID CMYB PATHWAY C-MYB transcription factor network
0.0 7.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.2 6.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 7.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 5.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 2.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 4.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 5.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.2 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 3.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation