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Illumina Body Map 2: averaged replicates

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Results for POU2F2_POU3F1

Z-value: 5.57

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.16 POU2F2
ENSG00000185668.5 POU3F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_426366320.593.3e-04Click!
POU3F1hg19_v2_chr1_-_38512450_38512474-0.364.2e-02Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_106552755 38.56 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr14_-_106692191 35.70 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr14_-_106573756 34.56 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr14_-_106994333 32.22 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr14_-_106791536 31.61 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr16_+_32077386 30.26 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106610852 30.11 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr14_-_106586656 29.69 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr16_+_33629600 29.47 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr14_-_107114267 28.10 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr14_-_106622419 27.62 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr16_+_33020496 26.76 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr22_+_22453093 25.23 ENST00000390283.2
IGLV8-61
immunoglobulin lambda variable 8-61
chr16_-_33647696 24.89 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr14_-_106845789 24.47 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_106816253 23.99 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr14_-_107199464 23.70 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr14_-_106518922 22.57 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr2_-_89399845 21.88 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr16_+_33006369 21.85 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr2_-_89247338 21.16 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr14_-_107013465 20.84 ENST00000390625.2
IGHV3-49
immunoglobulin heavy variable 3-49
chr14_-_107211459 20.79 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr2_+_90259593 20.66 ENST00000471857.1
IGKV1D-8
immunoglobulin kappa variable 1D-8
chr21_+_10862622 19.97 ENST00000302092.5
ENST00000559480.1
IGHV1OR21-1
immunoglobulin heavy variable 1/OR21-1 (non-functional)
chr2_+_89196746 18.91 ENST00000390244.2
IGKV5-2
immunoglobulin kappa variable 5-2
chr16_+_32063311 18.77 ENST00000426099.1
AC142381.1
AC142381.1
chr14_-_106926724 18.71 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_+_90121477 18.26 ENST00000483379.1
IGKV1D-17
immunoglobulin kappa variable 1D-17
chr14_-_107078851 17.89 ENST00000390628.2
IGHV1-58
immunoglobulin heavy variable 1-58
chr2_-_89568263 17.57 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr2_+_89952792 17.28 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr15_-_20193370 16.58 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr2_-_89340242 16.30 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr22_+_23089870 16.15 ENST00000390311.2
IGLV3-16
immunoglobulin lambda variable 3-16
chr2_-_89545079 16.13 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr2_+_90192768 16.04 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr16_+_33605231 15.85 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr2_+_114163945 14.49 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr2_+_90248739 14.01 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chr15_-_20170354 13.61 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr22_+_22764088 13.19 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr14_-_107170409 13.00 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr22_+_22735135 12.96 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr14_-_107283278 12.90 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr14_-_107049312 12.27 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr14_-_106725723 12.08 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr2_+_90211643 11.97 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr2_-_89266286 11.94 ENST00000464162.1
IGKV1-6
immunoglobulin kappa variable 1-6
chr2_-_89417335 11.71 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr14_-_106539557 11.42 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr22_+_22385332 11.29 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr2_+_90139056 10.93 ENST00000492446.1
IGKV1D-16
immunoglobulin kappa variable 1D-16
chr2_-_89619904 10.75 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr22_+_22712087 10.70 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr22_+_23029188 10.59 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr2_+_90273679 10.54 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr3_+_151591422 10.51 ENST00000362032.5
SUCNR1
succinate receptor 1
chr22_+_23040274 10.51 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr2_-_89327228 10.45 ENST00000483158.1
IGKV3-11
immunoglobulin kappa variable 3-11
chr2_+_90198535 10.12 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr22_+_23154239 10.03 ENST00000390315.2
IGLV3-10
immunoglobulin lambda variable 3-10
chr22_+_23010756 10.03 ENST00000390304.2
IGLV3-27
immunoglobulin lambda variable 3-27
chr22_+_23063100 10.03 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr7_-_142511084 9.98 ENST00000417977.2
TRBV30
T cell receptor beta variable 30 (gene/pseudogene)
chr14_-_106866934 9.89 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr22_+_23077065 9.79 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr2_+_89975669 9.61 ENST00000474213.1
IGKV2D-30
immunoglobulin kappa variable 2D-30
chr22_+_23165153 9.54 ENST00000390317.2
IGLV2-8
immunoglobulin lambda variable 2-8
chrX_-_48776292 9.53 ENST00000376509.4
PIM2
pim-2 oncogene
chr22_+_22930626 9.43 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr4_-_71532339 9.35 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532668 9.29 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532601 8.96 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532207 8.93 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_89901292 8.52 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr2_+_89923550 8.38 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr2_-_89459813 8.32 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr22_+_22550113 8.23 ENST00000390285.3
IGLV6-57
immunoglobulin lambda variable 6-57
chr2_+_89998789 8.16 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr22_+_23161491 7.82 ENST00000390316.2
IGLV3-9
immunoglobulin lambda variable 3-9 (gene/pseudogene)
chr14_-_107131560 7.22 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr3_+_98250743 7.21 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr2_+_90043607 7.15 ENST00000462693.1
IGKV2D-24
immunoglobulin kappa variable 2D-24 (non-functional)
chr16_+_23847339 7.14 ENST00000303531.7
PRKCB
protein kinase C, beta
chr6_+_26251835 7.06 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr2_+_90060377 7.03 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr16_+_23847355 7.02 ENST00000498058.1
PRKCB
protein kinase C, beta
chrX_+_12993336 7.02 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr6_-_31560729 6.70 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
NCR3
natural cytotoxicity triggering receptor 3
chr14_-_107219365 6.58 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr16_+_23847267 6.54 ENST00000321728.7
PRKCB
protein kinase C, beta
chr4_-_108204904 6.42 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr21_+_39644395 6.11 ENST00000398934.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr8_-_134114721 5.76 ENST00000522119.1
ENST00000523610.1
ENST00000521302.1
ENST00000519558.1
ENST00000519747.1
ENST00000517648.1
SLA
Src-like-adaptor
chr6_-_26216872 5.63 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr5_+_158527630 5.52 ENST00000523301.1
RP11-175K6.1
RP11-175K6.1
chr6_+_26273144 5.47 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr4_-_108204846 5.34 ENST00000513208.1
DKK2
dickkopf WNT signaling pathway inhibitor 2
chrX_+_12993202 5.32 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr7_-_27153454 5.28 ENST00000522456.1
HOXA3
homeobox A3
chr8_+_19796381 5.26 ENST00000524029.1
ENST00000522701.1
ENST00000311322.8
LPL
lipoprotein lipase
chr2_-_89597542 5.08 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr1_-_149814478 5.06 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr5_-_141030943 5.05 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr8_-_134114887 5.02 ENST00000519341.1
SLA
Src-like-adaptor
chr8_-_134114866 4.93 ENST00000524345.1
SLA
Src-like-adaptor
chr1_+_117297007 4.91 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr1_+_149822620 4.85 ENST00000369159.2
HIST2H2AA4
histone cluster 2, H2aa4
chr8_+_56792377 4.80 ENST00000520220.2
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr22_+_23114284 4.78 ENST00000390313.2
IGLV3-12
immunoglobulin lambda variable 3-12
chr22_+_22781853 4.70 ENST00000390300.2
IGLV5-37
immunoglobulin lambda variable 5-37
chr14_+_22217447 4.64 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr5_-_66492562 4.50 ENST00000256447.4
CD180
CD180 molecule
chr2_+_90458201 4.50 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr1_+_206730484 4.43 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr4_-_25865159 4.40 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_56792355 4.39 ENST00000519728.1
LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr14_+_22293618 4.29 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr6_-_27782548 4.25 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr3_-_112360116 4.09 ENST00000206423.3
ENST00000439685.2
CCDC80
coiled-coil domain containing 80
chr22_+_23046750 4.08 ENST00000390307.2
IGLV3-22
immunoglobulin lambda variable 3-22 (gene/pseudogene)
chr16_+_53164956 4.04 ENST00000563410.1
CHD9
chromodomain helicase DNA binding protein 9
chr12_-_31479045 3.97 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr2_+_90108504 3.95 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr4_+_40194570 3.87 ENST00000507851.1
RHOH
ras homolog family member H
chr6_-_27114577 3.86 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr6_+_143999185 3.85 ENST00000542769.1
ENST00000397980.3
PHACTR2
phosphatase and actin regulator 2
chr19_+_17858509 3.69 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr6_-_149806105 3.67 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr22_-_24096562 3.65 ENST00000398465.3
VPREB3
pre-B lymphocyte 3
chr6_+_27775899 3.64 ENST00000358739.3
HIST1H2AI
histone cluster 1, H2ai
chr6_-_55739542 3.62 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr8_-_134115118 3.53 ENST00000395352.3
ENST00000338087.5
SLA
Src-like-adaptor
chr7_-_27183263 3.52 ENST00000222726.3
HOXA5
homeobox A5
chr1_+_207669573 3.49 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr21_+_39644305 3.47 ENST00000398930.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_207669495 3.44 ENST00000367052.1
ENST00000367051.1
ENST00000367053.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chrX_+_134654540 3.43 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr1_+_149858461 3.42 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr5_-_2751762 3.41 ENST00000302057.5
ENST00000382611.6
IRX2
iroquois homeobox 2
chr19_-_44171817 3.39 ENST00000593714.1
PLAUR
plasminogen activator, urokinase receptor
chr4_-_154710210 3.34 ENST00000274063.4
SFRP2
secreted frizzled-related protein 2
chrX_+_99839799 3.33 ENST00000373031.4
TNMD
tenomodulin
chr8_-_125827922 3.24 ENST00000533516.1
RP11-1082L8.4
RP11-1082L8.4
chr6_-_128222103 3.19 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr7_+_50348268 3.19 ENST00000438033.1
ENST00000439701.1
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_63638339 3.13 ENST00000343837.3
ENST00000469440.1
SNTN
sentan, cilia apical structure protein
chr22_-_24096630 3.13 ENST00000248948.3
VPREB3
pre-B lymphocyte 3
chr6_+_37137939 3.11 ENST00000373509.5
PIM1
pim-1 oncogene
chr1_+_207669613 3.09 ENST00000367049.4
ENST00000529814.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr17_+_38171614 3.06 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr16_-_88752889 3.02 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr17_-_47841485 2.97 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr12_+_10124001 2.95 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr10_-_10836865 2.95 ENST00000446372.2
SFTA1P
surfactant associated 1, pseudogene
chr2_+_68962014 2.93 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr5_+_2752334 2.92 ENST00000505778.1
ENST00000515640.1
ENST00000397835.4
C5orf38
chromosome 5 open reading frame 38
chr19_-_50169064 2.92 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3
chr17_+_62461569 2.91 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chr1_+_201979645 2.82 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr12_-_31479107 2.81 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr7_+_18535321 2.78 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr7_+_18535346 2.77 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr21_-_36260980 2.77 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr19_-_18508396 2.77 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr17_+_38171681 2.77 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr19_-_50168962 2.75 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr19_-_47291843 2.71 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_-_87040233 2.67 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr10_-_10836919 2.64 ENST00000602763.1
ENST00000415590.2
ENST00000434919.2
SFTA1P
surfactant associated 1, pseudogene
chr18_-_52989525 2.59 ENST00000457482.3
TCF4
transcription factor 4
chr19_+_55128576 2.56 ENST00000396331.1
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr6_+_27833034 2.51 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr1_-_149859466 2.49 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr3_-_46069223 2.46 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr16_-_89008211 2.41 ENST00000569464.1
ENST00000569443.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr6_-_53013620 2.40 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr11_-_75917569 2.38 ENST00000322563.3
WNT11
wingless-type MMTV integration site family, member 11
chr19_+_35820064 2.37 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22
CD22 molecule
chr4_-_123377880 2.37 ENST00000226730.4
IL2
interleukin 2
chr19_-_40931891 2.32 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr14_+_103573853 2.32 ENST00000560304.1
EXOC3L4
exocyst complex component 3-like 4
chr17_+_72733350 2.32 ENST00000392613.5
ENST00000392612.3
ENST00000392610.1
RAB37
RAB37, member RAS oncogene family
chr11_-_5248294 2.30 ENST00000335295.4
HBB
hemoglobin, beta
chr11_-_118305921 2.28 ENST00000532619.1
RP11-770J1.4
RP11-770J1.4
chr7_+_16793160 2.27 ENST00000262067.4
TSPAN13
tetraspanin 13
chr5_+_2752258 2.27 ENST00000334000.3
C5orf38
chromosome 5 open reading frame 38
chr3_-_87039662 2.24 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr11_-_129872672 2.21 ENST00000531431.1
ENST00000527581.1
PRDM10
PR domain containing 10
chr5_-_175965008 2.20 ENST00000537487.1
RNF44
ring finger protein 44
chr6_+_6588902 2.18 ENST00000230568.4
LY86
lymphocyte antigen 86
chr12_-_51664058 2.14 ENST00000605627.1
SMAGP
small cell adhesion glycoprotein
chr5_+_2752216 2.14 ENST00000457752.2
C5orf38
chromosome 5 open reading frame 38
chr3_+_63638372 2.13 ENST00000496807.1
SNTN
sentan, cilia apical structure protein
chr12_+_122064398 2.12 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr19_+_39903185 2.12 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr4_+_40194609 2.09 ENST00000508513.1
RHOH
ras homolog family member H
chr12_+_10124110 2.08 ENST00000350667.4
CLEC12A
C-type lectin domain family 12, member A
chr1_+_170632250 2.05 ENST00000367760.3
PRRX1
paired related homeobox 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 1005.8 GO:0006958 complement activation, classical pathway(GO:0006958)
5.2 20.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
3.1 9.2 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
2.2 6.7 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.7 3.3 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.5 12.3 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.5 4.6 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.2 3.5 GO:0060435 bronchiole development(GO:0060435)
1.2 259.7 GO:0002377 immunoglobulin production(GO:0002377)
1.1 3.3 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.9 6.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.9 3.4 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.7 4.9 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.7 2.7 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.7 5.3 GO:0010159 specification of organ position(GO:0010159)
0.6 1.9 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.6 2.6 GO:0035548 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.6 2.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.6 2.4 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.6 1.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6 5.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.6 2.3 GO:0030185 nitric oxide transport(GO:0030185)
0.5 1.9 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.5 1.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.4 2.2 GO:0003409 optic cup structural organization(GO:0003409)
0.4 1.3 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077) negative regulation of B cell differentiation(GO:0045578) positive regulation of ovulation(GO:0060279)
0.4 1.7 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.4 3.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.4 5.9 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.4 5.7 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.4 5.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.4 1.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.3 4.1 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.3 1.4 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.3 0.7 GO:0031296 B cell costimulation(GO:0031296)
0.3 1.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 6.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 2.8 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 0.9 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.3 1.6 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 1.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 1.6 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2 0.5 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.2 3.0 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.2 3.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.6 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 0.9 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 1.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 1.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 2.9 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.2 1.3 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 3.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 3.2 GO:0043383 negative T cell selection(GO:0043383)
0.2 2.1 GO:0015889 cobalamin transport(GO:0015889)
0.2 2.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.2 1.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 1.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.2 3.0 GO:0060056 mammary gland involution(GO:0060056)
0.2 2.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 1.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 3.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 19.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 3.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 7.2 GO:0072678 T cell migration(GO:0072678)
0.1 1.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 3.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 7.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 9.5 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 3.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.7 GO:0019532 oxalate transport(GO:0019532)
0.1 6.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.8 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 2.0 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 2.3 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 2.4 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.1 0.3 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.5 GO:0072396 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 2.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.4 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.8 GO:0007379 segment specification(GO:0007379)
0.0 0.9 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 1.5 GO:0002076 osteoblast development(GO:0002076)
0.0 0.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 1.8 GO:0010165 response to X-ray(GO:0010165)
0.0 1.5 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 5.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.8 GO:0030903 notochord development(GO:0030903)
0.0 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 4.9 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.5 GO:0042756 drinking behavior(GO:0042756)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.4 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.0 0.5 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 1.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 2.3 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 6.0 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.4 GO:0040016 embryonic cleavage(GO:0040016)
0.0 4.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 3.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.0 GO:0006811 ion transport(GO:0006811)
0.0 1.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 2.3 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.6 GO:0060976 coronary vasculature development(GO:0060976)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.4 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 451.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.5 9.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.8 182.2 GO:0072562 blood microparticle(GO:0072562)
0.4 1.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 5.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 12.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 2.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.2 5.3 GO:0042627 chylomicron(GO:0042627)
0.2 3.4 GO:0071438 invadopodium membrane(GO:0071438)
0.2 1.5 GO:0032437 cuticular plate(GO:0032437)
0.2 6.8 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 3.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 1.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.9 GO:1990037 Lewy body core(GO:1990037)
0.1 317.0 GO:0005615 extracellular space(GO:0005615)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.5 GO:0043293 apoptosome(GO:0043293)
0.1 1.9 GO:0044327 dendritic spine head(GO:0044327)
0.1 4.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.1 GO:0005638 lamin filament(GO:0005638)
0.1 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 3.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.9 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 2.9 GO:0042629 mast cell granule(GO:0042629)
0.1 5.4 GO:0001772 immunological synapse(GO:0001772)
0.1 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 7.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 7.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 4.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 14.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.3 GO:0000145 exocyst(GO:0000145)
0.1 3.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 9.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 1.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 3.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 3.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 153.0 GO:0005576 extracellular region(GO:0005576)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 1.0 GO:0005903 brush border(GO:0005903)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.4 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 451.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
5.2 20.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
3.4 760.4 GO:0003823 antigen binding(GO:0003823)
3.3 10.0 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
1.4 11.6 GO:0043208 glycosphingolipid binding(GO:0043208)
1.3 5.3 GO:0017129 triglyceride binding(GO:0017129)
0.9 2.6 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.7 11.8 GO:0039706 co-receptor binding(GO:0039706)
0.5 4.6 GO:0070700 BMP receptor binding(GO:0070700)
0.5 3.4 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.4 3.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.4 4.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.4 2.3 GO:0030492 hemoglobin binding(GO:0030492)
0.3 2.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.3 7.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 3.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 5.7 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.7 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 1.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.2 3.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 12.7 GO:0003785 actin monomer binding(GO:0003785)
0.2 6.9 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 2.1 GO:0031419 cobalamin binding(GO:0031419)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 6.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.2 1.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 17.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 3.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 2.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.4 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 3.6 GO:0038191 neuropilin binding(GO:0038191)
0.1 4.1 GO:0001968 fibronectin binding(GO:0001968)
0.1 1.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.9 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.6 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.6 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.4 GO:0005522 profilin binding(GO:0005522)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.3 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 1.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 2.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 2.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.4 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 1.0 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 1.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 2.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 2.2 GO:0019208 phosphatase regulator activity(GO:0019208)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 20.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 10.6 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.2 1.8 PID IL5 PATHWAY IL5-mediated signaling events
0.2 12.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 9.9 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 3.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 14.2 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 15.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 7.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.4 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 1.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 4.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 5.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 7.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 9.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 19.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3 10.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 7.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 3.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 5.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 9.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 7.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 3.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 3.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 5.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 4.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 3.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 2.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 4.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.1 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)