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Illumina Body Map 2: averaged replicates
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Results for POU3F2
Z-value: 1.76
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Transcription factors associated with POU3F2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU3F2 | hg19_v2_chr6_+_99282570_99282591 | 0.58 | 4.8e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_-_76304731 Show fit | 2.37 |
ENST00000394907.3
|
neuregulin 4 |
|
| chr11_-_22881972 Show fit | 2.30 |
ENST00000532798.2
|
coiled-coil domain containing 179 |
|
| chr1_+_153175900 Show fit | 2.26 |
ENST00000368747.1
|
late cornified envelope-like proline-rich 1 |
|
| chr3_-_19975665 Show fit | 2.09 |
ENST00000295824.9
ENST00000389256.4 |
EF-hand domain family, member B |
|
| chr3_-_169487617 Show fit | 2.06 |
ENST00000330368.2
|
actin-related protein T3 |
|
| chr8_-_67940755 Show fit | 2.04 |
ENST00000324682.5
|
protein phosphatase 1, regulatory subunit 42 |
|
| chr20_+_44350968 Show fit | 1.99 |
ENST00000279058.3
|
serine peptidase inhibitor, Kunitz type 4 |
|
| chr2_-_202483867 Show fit | 1.96 |
ENST00000439802.1
ENST00000286195.3 ENST00000439140.1 ENST00000450242.1 |
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 |
|
| chr21_-_47352477 Show fit | 1.94 |
ENST00000593412.1
|
Uncharacterized protein |
|
| chr9_+_124922171 Show fit | 1.90 |
ENST00000373764.3
ENST00000536616.1 |
MORN repeat containing 5 |
Network of associatons between targets according to the STRING database.
First level regulatory network of POU3F2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.8 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.1 | 14.1 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 8.6 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 0.5 | 5.3 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.2 | 4.6 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.1 | 4.1 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 3.9 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 3.7 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.1 | 3.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 3.4 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.4 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 5.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 5.0 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.1 | 4.4 | GO:0032982 | myosin filament(GO:0032982) |
| 0.5 | 4.3 | GO:0002177 | manchette(GO:0002177) |
| 0.4 | 3.8 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 0.0 | 3.7 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 3.7 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 3.3 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 3.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 6.6 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.2 | 5.9 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 5.6 | GO:0008527 | taste receptor activity(GO:0008527) |
| 1.2 | 4.9 | GO:1904493 | Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493) |
| 0.2 | 4.9 | GO:0043495 | protein anchor(GO:0043495) |
| 0.3 | 4.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 4.2 | GO:0005549 | odorant binding(GO:0005549) |
| 0.1 | 4.2 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 4.1 | GO:0070063 | RNA polymerase binding(GO:0070063) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 2.8 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 2.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 2.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.8 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.8 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 1.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 1.2 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.9 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 3.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 3.8 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 3.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 3.3 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 3.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 3.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 3.0 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 2.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 2.8 | REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | Genes involved in GRB2 events in ERBB2 signaling |