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Illumina Body Map 2: averaged replicates

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Results for POU4F1_POU4F3

Z-value: 1.42

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Transcription factors associated with POU4F1_POU4F3

Gene Symbol Gene ID Gene Info
ENSG00000152192.6 POU class 4 homeobox 1
ENSG00000091010.4 POU class 4 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU4F1hg19_v2_chr13_-_79177673_791777010.281.2e-01Click!
POU4F3hg19_v2_chr5_+_145718587_1457186070.105.8e-01Click!

Activity profile of POU4F1_POU4F3 motif

Sorted Z-values of POU4F1_POU4F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_38821373 3.92 ENST00000394052.3
keratin 222
chr1_+_50574585 3.79 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr4_+_74269956 3.68 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
albumin
chr18_-_31803435 3.24 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
nucleolar protein 4
chr4_-_72649763 3.08 ENST00000513476.1
group-specific component (vitamin D binding protein)
chr2_-_88285309 3.07 ENST00000420840.2
RANBP2-like and GRIP domain containing 2
chr12_+_41221794 3.02 ENST00000547849.1
contactin 1
chr12_+_51985001 2.94 ENST00000354534.6
sodium channel, voltage gated, type VIII, alpha subunit
chr3_+_68055366 2.78 ENST00000496687.1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr22_+_30476163 2.63 ENST00000336726.6
HORMA domain containing 2
chr14_-_65409438 2.58 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr6_-_136847099 2.53 ENST00000438100.2
microtubule-associated protein 7
chr12_+_51984657 2.47 ENST00000550891.1
sodium channel, voltage gated, type VIII, alpha subunit
chrX_-_138724677 2.43 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF.2 cell line derived transforming sequence
chrX_-_138724994 2.37 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr9_+_34458771 2.28 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr3_+_35722487 2.26 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr6_-_136847610 2.26 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr19_+_17865011 2.23 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCH domain only 1
chr3_-_52860850 2.22 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr12_+_79357815 2.12 ENST00000547046.1
synaptotagmin I
chr2_+_87135076 2.08 ENST00000409776.2
RANBP2-like and GRIP domain containing 1
chr14_-_65409502 1.89 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr9_+_34458851 1.86 ENST00000545019.1
dynein, axonemal, intermediate chain 1
chr3_+_35722844 1.84 ENST00000436702.1
ENST00000438071.1
cAMP-regulated phosphoprotein, 21kDa
chr3_+_35722424 1.83 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chrX_-_106146547 1.79 ENST00000276173.4
ENST00000411805.1
ripply transcriptional repressor 1
chr18_-_31803169 1.78 ENST00000590712.1
nucleolar protein 4
chr18_+_76740189 1.78 ENST00000537592.2
ENST00000575389.2
spalt-like transcription factor 3
chr22_+_30477000 1.75 ENST00000403975.1
HORMA domain containing 2
chr12_+_41221975 1.75 ENST00000552913.1
contactin 1
chr3_+_46742823 1.71 ENST00000326431.3
transmembrane inner ear
chr19_-_36304201 1.71 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr1_+_63063152 1.70 ENST00000371129.3
angiopoietin-like 3
chr2_+_185463093 1.61 ENST00000302277.6
zinc finger protein 804A
chr16_-_51185172 1.55 ENST00000251020.4
spalt-like transcription factor 1
chr11_-_35441524 1.55 ENST00000395750.1
ENST00000449068.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr16_-_51185149 1.51 ENST00000566102.1
ENST00000541611.1
spalt-like transcription factor 1
chr11_-_35441597 1.50 ENST00000395753.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr12_+_49740700 1.49 ENST00000549441.2
ENST00000395069.3
DnaJ (Hsp40) homolog, subfamily C, member 22
chr14_-_101036119 1.47 ENST00000355173.2
brain-enriched guanylate kinase-associated
chr5_+_139739772 1.47 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr3_-_194072019 1.41 ENST00000429275.1
ENST00000323830.3
carboxypeptidase N, polypeptide 2
chr17_-_50236039 1.34 ENST00000451037.2
carbonic anhydrase X
chr17_+_18012020 1.32 ENST00000205890.5
myosin XVA
chr16_+_24621546 1.31 ENST00000566108.1
CTD-2540M10.1
chr21_-_37914898 1.27 ENST00000399136.1
claudin 14
chr2_-_209054709 1.26 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
chromosome 2 open reading frame 80
chr10_-_128359008 1.25 ENST00000488181.1
chromosome 10 open reading frame 90
chr12_-_9885888 1.24 ENST00000327839.3
C-type lectin-like 1
chr19_+_19639704 1.21 ENST00000514277.4
YjeF N-terminal domain containing 3
chr19_+_19639670 1.21 ENST00000436027.5
YjeF N-terminal domain containing 3
chr11_-_7698453 1.16 ENST00000524608.1
cytochrome b5 reductase 2
chr17_-_10741762 1.16 ENST00000580256.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr2_+_182850551 1.14 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_+_179318295 1.11 ENST00000442710.1
deafness, autosomal recessive 59
chr19_-_13734804 1.11 ENST00000574974.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr15_+_58724184 1.09 ENST00000433326.2
lipase, hepatic
chr4_-_21546272 1.07 ENST00000509207.1
Kv channel interacting protein 4
chr9_-_123812542 1.07 ENST00000223642.1
complement component 5
chr1_+_149239529 1.07 ENST00000457216.2
RP11-403I13.4
chr1_+_101003687 1.04 ENST00000315033.4
G protein-coupled receptor 88
chr1_-_108231101 1.04 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr1_+_160336851 1.04 ENST00000302101.5
nescient helix loop helix 1
chr9_-_74675521 1.00 ENST00000377024.3
chromosome 9 open reading frame 57
chr4_+_159236462 0.99 ENST00000460056.2
relaxin/insulin-like family peptide receptor 1
chr2_-_183387283 0.97 ENST00000435564.1
phosphodiesterase 1A, calmodulin-dependent
chr12_+_100750846 0.95 ENST00000323346.5
solute carrier family 17 (vesicular glutamate transporter), member 8
chr10_-_128359074 0.95 ENST00000544758.1
chromosome 10 open reading frame 90
chr5_-_13944652 0.93 ENST00000265104.4
dynein, axonemal, heavy chain 5
chr11_+_58706944 0.90 ENST00000532726.1
glycine-N-acyltransferase-like 1
chrX_-_142605301 0.90 ENST00000370503.2
SPANX family, member N3
chr15_+_76352178 0.89 ENST00000388942.3
chromosome 15 open reading frame 27
chr22_-_30970560 0.88 ENST00000402369.1
ENST00000406361.1
galactose-3-O-sulfotransferase 1
chr8_-_110986918 0.88 ENST00000297404.1
potassium channel, subfamily V, member 1
chr11_-_83393429 0.88 ENST00000426717.2
discs, large homolog 2 (Drosophila)
chr2_+_179317994 0.87 ENST00000375129.4
deafness, autosomal recessive 59
chr6_-_10115007 0.87 ENST00000485268.1
orofacial cleft 1 candidate 1
chr11_+_98891797 0.87 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
contactin 5
chr17_-_72855989 0.84 ENST00000293190.5
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr20_+_30555805 0.82 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr17_-_56492989 0.80 ENST00000583753.1
ring finger protein 43
chr5_-_135290705 0.79 ENST00000274507.1
leukocyte cell-derived chemotaxin 2
chr19_-_51141196 0.78 ENST00000338916.4
synaptotagmin III
chr1_-_197036364 0.78 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr11_-_83393457 0.77 ENST00000404783.3
discs, large homolog 2 (Drosophila)
chrX_-_72097698 0.77 ENST00000373530.1
DMRT-like family C1
chr2_-_183387430 0.77 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr1_+_47603109 0.77 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
cytochrome P450, family 4, subfamily A, polypeptide 22
chr3_-_185826855 0.75 ENST00000306376.5
ets variant 5
chrX_+_72062802 0.74 ENST00000373533.1
DMRT-like family C1B
chr10_-_128210005 0.74 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
chromosome 10 open reading frame 90
chr2_+_133174147 0.74 ENST00000329321.3
G protein-coupled receptor 39
chrX_+_72062617 0.74 ENST00000440247.1
DMRT-like family C1B
chr5_-_11589131 0.72 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr7_-_107880508 0.72 ENST00000425651.2
neuronal cell adhesion molecule
chr18_-_70305745 0.72 ENST00000581073.1
cerebellin 2 precursor
chr11_-_83393303 0.70 ENST00000398304.1
ENST00000420775.2
discs, large homolog 2 (Drosophila)
chr17_+_28268623 0.69 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EF-hand calcium binding domain 5
chr18_+_47088401 0.69 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial
chr2_-_183387064 0.67 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr7_-_100026280 0.67 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr19_+_54466179 0.65 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr11_-_26593649 0.65 ENST00000455601.2
mucin 15, cell surface associated
chr5_-_11588907 0.63 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr12_-_120241187 0.63 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr18_-_24443151 0.62 ENST00000440832.3
aquaporin 4
chr1_-_248845629 0.60 ENST00000342623.3
olfactory receptor, family 14, subfamily I, member 1
chr22_-_38506619 0.60 ENST00000332536.5
ENST00000381669.3
BAI1-associated protein 2-like 2
chr2_+_87144738 0.60 ENST00000559485.1
RANBP2-like and GRIP domain containing 1
chr12_+_81664424 0.59 ENST00000549161.1
ENST00000550138.1
RP11-121G22.3
chr4_-_69817481 0.59 ENST00000251566.4
UDP glucuronosyltransferase 2 family, polypeptide A3
chr19_-_39402798 0.58 ENST00000571838.1
coiled-coil glutamate-rich protein 2
chr9_-_16253112 0.58 ENST00000380683.1
chromosome 9 open reading frame 92
chr2_+_197577841 0.56 ENST00000409270.1
coiled-coil domain containing 150
chr11_-_88799113 0.55 ENST00000393294.3
glutamate receptor, metabotropic 5
chr7_+_99195677 0.55 ENST00000431679.1
GS1-259H13.2
chr22_-_30970498 0.53 ENST00000431313.1
galactose-3-O-sulfotransferase 1
chr7_-_15014398 0.50 ENST00000437998.1
diacylglycerol kinase, beta 90kDa
chr6_-_127840021 0.50 ENST00000465909.2
SOGA family member 3
chr6_-_76782371 0.50 ENST00000369950.3
ENST00000369963.3
interphotoreceptor matrix proteoglycan 1
chr11_-_69587718 0.49 ENST00000602104.1
Uncharacterized protein
chr19_-_55677920 0.47 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
dynein, axonemal, assembly factor 3
chr19_+_56368803 0.45 ENST00000587891.1
NLR family, pyrin domain containing 4
chr9_+_35673853 0.45 ENST00000378357.4
carbonic anhydrase IX
chr3_-_33686925 0.44 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr6_-_26108355 0.44 ENST00000338379.4
histone cluster 1, H1t
chr12_+_110011571 0.43 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
mevalonate kinase
chr14_+_101297740 0.41 ENST00000555928.1
maternally expressed 3 (non-protein coding)
chr3_-_74570291 0.41 ENST00000263665.6
contactin 3 (plasmacytoma associated)
chr1_-_222014008 0.41 ENST00000431729.1
RP11-191N8.2
chr2_+_182850743 0.41 ENST00000409702.1
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr5_-_135290651 0.40 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr13_-_20110902 0.38 ENST00000390680.2
ENST00000382977.4
ENST00000382975.4
ENST00000457266.2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr4_-_103998439 0.38 ENST00000503230.1
ENST00000503818.1
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
chr2_+_65663812 0.38 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
chr17_+_37783197 0.38 ENST00000582680.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_35013217 0.38 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr10_+_90346519 0.38 ENST00000371939.3
lipase, family member J
chr11_+_86085778 0.37 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
coiled-coil domain containing 81
chr2_+_191221240 0.37 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr13_-_70682590 0.37 ENST00000377844.4
kelch-like family member 1
chr22_+_17956618 0.36 ENST00000262608.8
cat eye syndrome chromosome region, candidate 2
chr1_-_47017199 0.36 ENST00000481882.2
kinocilin
chr6_-_127840336 0.36 ENST00000525778.1
SOGA family member 3
chr22_+_43011247 0.35 ENST00000602478.1
RNA, U12 small nuclear
chr9_-_21166659 0.34 ENST00000380225.1
interferon, alpha 21
chr2_-_26781521 0.34 ENST00000403946.3
ENST00000272371.2
otoferlin
chr11_+_22696314 0.34 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr3_-_33686743 0.34 ENST00000333778.6
ENST00000539981.1
cytoplasmic linker associated protein 2
chr1_-_154580616 0.34 ENST00000368474.4
adenosine deaminase, RNA-specific
chr10_-_128975273 0.34 ENST00000424811.2
family with sequence similarity 196, member A
chr17_+_37782955 0.34 ENST00000580825.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr17_+_37783453 0.33 ENST00000579000.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr20_-_29978383 0.33 ENST00000339144.3
ENST00000376321.3
defensin, beta 119
chr22_-_39268308 0.33 ENST00000407418.3
chromobox homolog 6
chr1_+_161691353 0.32 ENST00000367948.2
Fc receptor-like B
chr4_+_68424434 0.32 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr14_+_22580233 0.31 ENST00000390454.2
T cell receptor alpha variable 25
chr2_+_47454054 0.31 ENST00000426892.1
AC106869.2
chr17_-_37123646 0.30 ENST00000378079.2
F-box protein 47
chr10_+_104614008 0.30 ENST00000369883.3
chromosome 10 open reading frame 32
chr6_+_126102292 0.30 ENST00000368357.3
nuclear receptor coactivator 7
chr12_-_23737534 0.30 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr11_-_26593677 0.30 ENST00000527569.1
mucin 15, cell surface associated
chr4_+_146601356 0.29 ENST00000438731.1
ENST00000511965.1
chromosome 4 open reading frame 51
chr9_-_107361788 0.29 ENST00000374779.2
olfactory receptor, family 13, subfamily C, member 5
chr17_+_37783170 0.29 ENST00000254079.4
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr2_+_40973618 0.28 ENST00000420187.1
AC007317.1
chr4_-_122085469 0.27 ENST00000057513.3
TNFAIP3 interacting protein 3
chr4_-_16085314 0.27 ENST00000510224.1
prominin 1
chr3_-_167371704 0.27 ENST00000488012.1
WD repeat domain 49
chr12_+_130554803 0.27 ENST00000535487.1
RP11-474D1.2
chr3_-_167371740 0.26 ENST00000466760.1
ENST00000479765.1
WD repeat domain 49
chr10_-_112678904 0.26 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBSome interacting protein 1
chr14_+_22978168 0.26 ENST00000390505.1
T cell receptor alpha joining 32
chr16_-_67217844 0.26 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895-like
chr1_-_95538492 0.26 ENST00000370205.5
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr11_-_111649074 0.26 ENST00000534218.1
RP11-108O10.2
chr19_-_23941639 0.25 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
zinc finger protein 681
chr10_+_135207598 0.25 ENST00000477902.2
mitochondrial ribosome-associated GTPase 1
chr2_-_183106641 0.24 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr6_-_2634820 0.24 ENST00000296847.3
chromosome 6 open reading frame 195
chr4_-_16085340 0.24 ENST00000508167.1
prominin 1
chr19_-_46580352 0.24 ENST00000601672.1
IGF-like family member 4
chr16_-_52061283 0.24 ENST00000566314.1
chromosome 16 open reading frame 97
chr3_-_185826718 0.23 ENST00000413301.1
ENST00000421809.1
ets variant 5
chr10_-_112678692 0.23 ENST00000605742.1
BBSome interacting protein 1
chr5_-_39270725 0.23 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr9_-_4666421 0.23 ENST00000381895.5
spermatogenesis associated 6-like
chr13_+_113698946 0.23 ENST00000397021.1
MCF.2 cell line derived transforming sequence-like
chr10_+_135207623 0.23 ENST00000317502.6
ENST00000432508.3
mitochondrial ribosome-associated GTPase 1
chr2_+_169757750 0.23 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
glucose-6-phosphatase, catalytic, 2
chr9_-_4666337 0.22 ENST00000381890.5
spermatogenesis associated 6-like
chr20_+_57875758 0.22 ENST00000395654.3
endothelin 3
chr10_+_104613980 0.21 ENST00000339834.5
chromosome 10 open reading frame 32
chr13_+_46039037 0.21 ENST00000349995.5
component of oligomeric golgi complex 3
chr19_-_55677999 0.21 ENST00000532817.1
ENST00000527223.2
ENST00000391720.4
dynein, axonemal, assembly factor 3
chr6_-_52859046 0.20 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr6_-_161695074 0.20 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4

Network of associatons between targets according to the STRING database.

First level regulatory network of POU4F1_POU4F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 3.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.4 4.4 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.4 2.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.3 1.8 GO:0001757 somite specification(GO:0001757)
0.3 0.8 GO:0033058 directional locomotion(GO:0033058)
0.3 3.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 1.0 GO:0061743 motor learning(GO:0061743)
0.2 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 1.4 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 5.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.2 0.7 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 1.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 5.7 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.6 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.0 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.3 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.8 GO:0002933 lipid hydroxylation(GO:0002933)
0.1 0.5 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.1 1.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 3.1 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 5.6 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 1.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.2 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.1 0.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.3 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.8 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.7 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 3.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 2.1 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.9 GO:0046710 GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120)
0.0 4.8 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 5.1 GO:0021549 cerebellum development(GO:0021549)
0.0 0.2 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 1.9 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 5.7 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.6 GO:0006833 water transport(GO:0006833)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.1 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 3.9 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 0.0 GO:0007113 endomitotic cell cycle(GO:0007113)
0.0 1.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 5.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.2 GO:0042330 chemotaxis(GO:0006935) taxis(GO:0042330)
0.0 0.6 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 3.2 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0050777 negative regulation of immune response(GO:0050777)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.3 GO:0007420 brain development(GO:0007420)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999) nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 GO:0036157 outer dynein arm(GO:0036157)
0.3 1.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 2.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 5.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 2.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.1 GO:0010369 chromocenter(GO:0010369)
0.1 0.8 GO:0005579 membrane attack complex(GO:0005579)
0.1 4.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 2.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 3.1 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.8 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.6 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 6.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 4.9 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 4.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.1 GO:0005882 intermediate filament(GO:0005882)
0.0 1.9 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 9.2 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.8 2.4 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.4 1.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.4 2.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 3.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 1.3 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.2 0.9 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.2 2.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 4.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 5.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 3.7 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 4.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.4 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 1.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 3.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.8 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.8 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.0 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 2.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 5.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 1.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 4.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 3.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 4.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 3.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 5.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 4.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling