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Illumina Body Map 2: averaged replicates
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Results for POU6F2
Z-value: 1.78
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Transcription factors associated with POU6F2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU6F2 | hg19_v2_chr7_+_39125365_39125489 | 0.46 | 7.6e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of POU6F2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 17.0 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.7 | 8.9 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 2.3 | 6.9 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.1 | 6.6 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.3 | 4.4 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.2 | 4.4 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.2 | 4.3 | GO:0070166 | enamel mineralization(GO:0070166) |
| 0.0 | 4.1 | GO:0032411 | positive regulation of transporter activity(GO:0032411) |
| 0.1 | 3.7 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.9 | 3.6 | GO:0061289 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.6 | 6.9 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 4.9 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 4.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 4.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 3.6 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 3.2 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.0 | 2.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 2.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 2.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.5 | 6.9 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 5.8 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.2 | 5.1 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.5 | 4.4 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.2 | 4.4 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.1 | 4.4 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 4.0 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 3.6 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 1.1 | 3.3 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 5.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 3.6 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 3.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.1 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 2.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.8 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.7 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 1.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 7.8 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.2 | 6.9 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 6.6 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 4.4 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.2 | 3.3 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 3.2 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 2.4 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 2.4 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.2 | 2.1 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |