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Illumina Body Map 2: averaged replicates

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Results for POU6F2

Z-value: 1.78

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Transcription factors associated with POU6F2

Gene Symbol Gene ID Gene Info
ENSG00000106536.15 POU class 6 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F2hg19_v2_chr7_+_39125365_391254890.467.6e-03Click!

Activity profile of POU6F2 motif

Sorted Z-values of POU6F2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_73038822 4.57 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chrX_+_43515467 4.43 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr7_-_73038867 4.36 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLX interacting protein-like
chr8_+_92261516 4.35 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr2_-_217560248 3.92 ENST00000233813.4
insulin-like growth factor binding protein 5
chr10_-_128210005 3.60 ENST00000284694.7
ENST00000454341.1
ENST00000432642.1
ENST00000392694.1
chromosome 10 open reading frame 90
chr15_-_54025300 3.41 ENST00000559418.1
WD repeat domain 72
chr20_+_56136136 3.29 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr3_+_159557637 3.25 ENST00000445224.2
schwannomin interacting protein 1
chr12_-_16758835 3.21 ENST00000541295.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_103344615 3.20 ENST00000546844.1
phenylalanine hydroxylase
chr12_-_16758873 3.18 ENST00000535535.1
LIM domain only 3 (rhombotin-like 2)
chr21_+_17442799 3.05 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr12_-_16762802 3.04 ENST00000534946.1
LIM domain only 3 (rhombotin-like 2)
chr2_-_217559517 2.98 ENST00000449583.1
insulin-like growth factor binding protein 5
chr11_-_82444892 2.89 ENST00000329203.3
family with sequence similarity 181, member B
chr12_-_16759440 2.87 ENST00000537304.1
LIM domain only 3 (rhombotin-like 2)
chrX_-_18690210 2.83 ENST00000379984.3
retinoschisin 1
chr6_-_100912785 2.59 ENST00000369208.3
single-minded family bHLH transcription factor 1
chr3_+_35685113 2.58 ENST00000419330.1
cAMP-regulated phosphoprotein, 21kDa
chr17_-_10421853 2.51 ENST00000226207.5
myosin, heavy chain 1, skeletal muscle, adult
chr20_+_42187682 2.48 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr11_-_26593649 2.46 ENST00000455601.2
mucin 15, cell surface associated
chr17_+_37784749 2.43 ENST00000394265.1
ENST00000394267.2
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr12_-_87232644 2.40 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr11_+_107461804 2.30 ENST00000531234.1
ELMO/CED-12 domain containing 1
chr5_-_96478466 2.24 ENST00000274382.4
Lix1 homolog (chicken)
chr11_-_26593779 2.22 ENST00000529533.1
mucin 15, cell surface associated
chr11_-_70672645 2.14 ENST00000423696.2
SH3 and multiple ankyrin repeat domains 2
chr6_-_87804815 2.13 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr12_-_16762971 2.03 ENST00000540590.1
LIM domain only 3 (rhombotin-like 2)
chr5_-_36301984 1.96 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr1_-_234667504 1.96 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chr11_-_27494309 1.94 ENST00000389858.4
leucine-rich repeat containing G protein-coupled receptor 4
chr6_+_151646800 1.93 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr11_-_129062093 1.93 ENST00000310343.9
Rho GTPase activating protein 32
chr11_-_26593677 1.92 ENST00000527569.1
mucin 15, cell surface associated
chr20_+_42187608 1.92 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chr3_+_147657764 1.83 ENST00000467198.1
ENST00000485006.1
RP11-71N10.1
chrX_-_13835147 1.81 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr11_+_125034586 1.79 ENST00000298282.9
PBX/knotted 1 homeobox 2
chr11_+_45918092 1.78 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr11_+_65554493 1.69 ENST00000335987.3
ovo-like zinc finger 1
chr12_-_100378006 1.65 ENST00000547776.2
ENST00000329257.7
ENST00000547010.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr11_-_27494279 1.63 ENST00000379214.4
leucine-rich repeat containing G protein-coupled receptor 4
chr14_+_32798547 1.62 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr14_+_32798462 1.59 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr21_-_31864275 1.58 ENST00000334063.4
keratin associated protein 19-3
chr1_-_31666767 1.56 ENST00000530145.1
Na+/K+ transporting ATPase interacting 1
chr11_-_93583697 1.52 ENST00000409977.1
V-set and transmembrane domain containing 5
chr1_+_31883048 1.51 ENST00000536859.1
serine incorporator 2
chr13_-_44735393 1.49 ENST00000400419.1
small integral membrane protein 2
chr9_+_109625378 1.48 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
zinc finger protein 462
chr4_+_110749143 1.48 ENST00000317735.4
retinal pigment epithelium-derived rhodopsin homolog
chr5_-_96478457 1.47 ENST00000512378.1
Lix1 homolog (chicken)
chr3_+_111717511 1.45 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr12_-_16761007 1.43 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr12_-_71031185 1.42 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
protein tyrosine phosphatase, receptor type, B
chr8_-_37189432 1.39 ENST00000518765.1
RP11-527N22.1
chr14_-_27066960 1.37 ENST00000539517.2
neuro-oncological ventral antigen 1
chr5_+_125706998 1.35 ENST00000506445.1
GRAM domain containing 3
chr3_+_111717600 1.34 ENST00000273368.4
transgelin 3
chr2_+_44502597 1.34 ENST00000260649.6
ENST00000409387.1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr2_+_7118755 1.33 ENST00000433456.1
ring finger protein 144A
chr4_+_110834033 1.32 ENST00000509793.1
ENST00000265171.5
epidermal growth factor
chr15_+_67390920 1.31 ENST00000559092.1
ENST00000560175.1
SMAD family member 3
chr9_-_13165457 1.30 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
multiple PDZ domain protein
chr1_-_159832438 1.27 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr8_+_77593474 1.24 ENST00000455469.2
ENST00000050961.6
zinc finger homeobox 4
chr12_-_16761117 1.23 ENST00000538051.1
LIM domain only 3 (rhombotin-like 2)
chr3_+_111718036 1.22 ENST00000455401.2
transgelin 3
chr7_+_5465382 1.22 ENST00000609130.1
RP11-1275H24.2
chr1_-_204329013 1.22 ENST00000272203.3
ENST00000414478.1
pleckstrin homology domain containing, family A member 6
chr4_+_66536248 1.19 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
chr13_+_58206655 1.19 ENST00000377918.3
protocadherin 17
chr22_+_30792846 1.18 ENST00000312932.9
ENST00000428195.1
SEC14-like 2 (S. cerevisiae)
chr14_-_36989336 1.15 ENST00000522719.2
NK2 homeobox 1
chr3_+_189507523 1.15 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr11_-_102709441 1.15 ENST00000434103.1
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr21_-_42219065 1.11 ENST00000400454.1
Down syndrome cell adhesion molecule
chr17_-_10372875 1.11 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr2_+_44502630 1.08 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr21_+_33671160 1.08 ENST00000303645.5
melanocortin 2 receptor accessory protein
chr2_+_35056422 1.07 ENST00000592523.1
ENST00000588944.1
ENST00000585391.1
ENST00000591221.1
ENST00000586769.1
ENST00000588650.1
AC012593.1
chr8_-_142012169 1.06 ENST00000517453.1
protein tyrosine kinase 2
chrX_+_86772707 1.05 ENST00000373119.4
kelch-like family member 4
chr1_+_50571949 1.03 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chr12_-_86230315 1.01 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr18_-_24129367 1.01 ENST00000408011.3
potassium channel tetramerization domain containing 1
chr14_-_36988882 1.01 ENST00000498187.2
NK2 homeobox 1
chr8_+_77593448 1.00 ENST00000521891.2
zinc finger homeobox 4
chr3_-_127541194 1.00 ENST00000453507.2
monoglyceride lipase
chr1_+_175036966 0.99 ENST00000239462.4
tenascin N
chr9_-_79520989 0.98 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
prune homolog 2 (Drosophila)
chr1_-_153123345 0.98 ENST00000368748.4
small proline-rich protein 2G
chr11_-_36619771 0.98 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
recombination activating gene 2
chr12_-_71031220 0.96 ENST00000334414.6
protein tyrosine phosphatase, receptor type, B
chr6_+_25754927 0.95 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr7_-_16840820 0.95 ENST00000450569.1
anterior gradient 2
chr7_+_6655225 0.94 ENST00000457543.3
zinc finger protein 853
chr6_+_42123141 0.94 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr6_+_50786414 0.94 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr1_+_107683644 0.93 ENST00000370067.1
netrin G1
chr4_+_88571429 0.92 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr3_+_111718173 0.91 ENST00000494932.1
transgelin 3
chr1_-_182641037 0.90 ENST00000483095.2
regulator of G-protein signaling 8
chr2_-_105030466 0.90 ENST00000449772.1
AC068535.3
chr7_-_14029283 0.89 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr3_-_33686925 0.88 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr21_+_17443521 0.87 ENST00000456342.1
long intergenic non-protein coding RNA 478
chr17_-_39553844 0.87 ENST00000251645.2
keratin 31
chrX_+_86772787 0.86 ENST00000373114.4
kelch-like family member 4
chr5_+_126984710 0.86 ENST00000379445.3
cortexin 3
chr6_+_4087664 0.86 ENST00000430835.2
chromosome 6 open reading frame 201
chr7_-_14028488 0.85 ENST00000405358.4
ets variant 1
chr8_-_10512569 0.84 ENST00000382483.3
retinitis pigmentosa 1-like 1
chr4_-_66536196 0.84 ENST00000511294.1
EPH receptor A5
chr9_+_130853715 0.84 ENST00000373066.5
ENST00000432073.2
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr5_+_159343688 0.80 ENST00000306675.3
adrenoceptor alpha 1B
chr5_-_124082279 0.80 ENST00000513986.1
zinc finger protein 608
chr15_-_37393406 0.80 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chrX_-_151619746 0.77 ENST00000370314.4
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr4_-_22444733 0.76 ENST00000508133.1
G protein-coupled receptor 125
chr8_-_42358742 0.74 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr17_-_29624343 0.74 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chr12_-_15815626 0.74 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr3_-_51909600 0.74 ENST00000446461.1
IQ motif containing F5
chr5_-_156486120 0.73 ENST00000522693.1
hepatitis A virus cellular receptor 1
chr3_+_189507460 0.72 ENST00000434928.1
tumor protein p63
chr8_-_42396185 0.70 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr7_+_129007964 0.69 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
adenosylhomocysteinase-like 2
chr1_-_208417620 0.69 ENST00000367033.3
plexin A2
chr15_-_33447055 0.67 ENST00000559047.1
ENST00000561249.1
formin 1
chr15_+_96869165 0.67 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr22_+_20905269 0.66 ENST00000457322.1
mediator complex subunit 15
chr15_-_88247083 0.66 ENST00000560439.1
RP11-648K4.2
chr21_+_17443434 0.66 ENST00000400178.2
long intergenic non-protein coding RNA 478
chr15_+_58702742 0.65 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr1_+_50574585 0.65 ENST00000371824.1
ENST00000371823.4
ELAV like neuron-specific RNA binding protein 4
chr8_+_42396274 0.63 ENST00000438528.3
small integral membrane protein 19
chr1_+_10271674 0.63 ENST00000377086.1
kinesin family member 1B
chr1_+_107683436 0.62 ENST00000370068.1
netrin G1
chr1_-_182640988 0.61 ENST00000367556.1
regulator of G-protein signaling 8
chr12_-_131118370 0.57 ENST00000541840.1
RP11-662M24.2
chr19_-_28957557 0.57 ENST00000585697.1
ENST00000591920.1
AC005307.3
chr2_+_102721023 0.55 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr8_+_39792474 0.55 ENST00000502986.2
indoleamine 2,3-dioxygenase 2
chr8_-_42234745 0.55 ENST00000220812.2
dickkopf WNT signaling pathway inhibitor 4
chr3_+_189507432 0.55 ENST00000354600.5
tumor protein p63
chrX_-_23926004 0.55 ENST00000379226.4
ENST00000379220.3
apolipoprotein O
chr6_-_138866823 0.54 ENST00000342260.5
NHS-like 1
chr16_-_54962415 0.54 ENST00000501177.3
ENST00000559598.2
colorectal neoplasia differentially expressed (non-protein coding)
chr15_+_101402041 0.54 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
chr17_-_33390667 0.54 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr22_-_32767017 0.52 ENST00000400234.1
RFPL3 antisense
chr10_-_23633720 0.50 ENST00000323327.4
chromosome 10 open reading frame 67
chr11_+_101918153 0.49 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr2_+_128403720 0.49 ENST00000272644.3
G protein-coupled receptor 17
chr5_+_36606700 0.49 ENST00000416645.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr5_-_139726181 0.47 ENST00000507104.1
ENST00000230990.6
heparin-binding EGF-like growth factor
chr3_+_2553281 0.47 ENST00000434053.1
contactin 4
chr10_-_102989551 0.45 ENST00000370193.2
ladybird homeobox 1
chr2_-_80531824 0.44 ENST00000295057.3
leucine rich repeat transmembrane neuronal 1
chr22_+_20905422 0.43 ENST00000424287.1
ENST00000423862.1
mediator complex subunit 15
chr6_-_33160231 0.43 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
collagen, type XI, alpha 2
chr3_+_193809263 0.42 ENST00000457815.1
RP11-135A1.3
chr11_-_71823715 0.40 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr1_+_19967014 0.38 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr21_-_31971219 0.37 ENST00000334897.3
keratin associated protein 6-2
chr6_+_76330355 0.36 ENST00000483859.2
SUMO1/sentrin specific peptidase 6
chr7_+_129015484 0.36 ENST00000490911.1
adenosylhomocysteinase-like 2
chrX_+_99839799 0.35 ENST00000373031.4
tenomodulin
chr13_-_110438914 0.33 ENST00000375856.3
insulin receptor substrate 2
chrX_+_3189861 0.32 ENST00000457435.1
ENST00000420429.2
chromosome X open reading frame 28
chr11_-_71823796 0.31 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr2_+_138721850 0.29 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr5_-_134914673 0.29 ENST00000512158.1
chemokine (C-X-C motif) ligand 14
chr4_-_66536057 0.29 ENST00000273854.3
EPH receptor A5
chr2_+_29001711 0.28 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr12_-_24097236 0.28 ENST00000538083.1
SRY (sex determining region Y)-box 5
chr3_+_77088989 0.27 ENST00000461745.1
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr3_-_57199397 0.27 ENST00000296318.7
interleukin 17 receptor D
chr2_-_216003127 0.25 ENST00000412081.1
ENST00000272895.7
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_47655686 0.24 ENST00000294338.2
PDZK1 interacting protein 1
chr2_-_80531399 0.23 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
leucine rich repeat transmembrane neuronal 1
chr7_+_116660246 0.23 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr1_-_201140673 0.23 ENST00000367333.2
transmembrane protein 9
chr1_+_61869748 0.20 ENST00000357977.5
nuclear factor I/A
chr2_+_128403439 0.20 ENST00000544369.1
G protein-coupled receptor 17
chr7_+_129015671 0.20 ENST00000466993.1
adenosylhomocysteinase-like 2
chrX_-_106243451 0.19 ENST00000355610.4
ENST00000535534.1
MORC family CW-type zinc finger 4
chr5_+_115177178 0.19 ENST00000316788.7
adaptor-related protein complex 3, sigma 1 subunit
chr2_-_80531720 0.18 ENST00000416268.1
leucine rich repeat transmembrane neuronal 1
chr6_-_155635583 0.18 ENST00000367166.4
transcription factor B1, mitochondrial
chr4_-_74486347 0.17 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr18_+_44812072 0.17 ENST00000598649.1
ENST00000586905.2
CTD-2130O13.1
chr9_-_21482312 0.16 ENST00000448696.3
interferon, epsilon
chr6_+_151042224 0.16 ENST00000358517.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr15_+_74421961 0.15 ENST00000565159.1
ENST00000567206.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_+_148287657 0.15 ENST00000307003.2
chromosome 7 open reading frame 33

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.2 17.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.9 3.6 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8 3.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.7 8.9 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.7 2.8 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 2.4 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.4 3.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 1.2 GO:1990709 presynaptic active zone organization(GO:1990709)
0.3 1.7 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.3 2.4 GO:0015811 L-cystine transport(GO:0015811)
0.3 1.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 4.4 GO:0042420 dopamine catabolic process(GO:0042420)
0.3 1.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 1.5 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 2.0 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 2.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 4.4 GO:0019532 oxalate transport(GO:0019532)
0.2 4.3 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.8 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.2 1.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 1.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.2 3.2 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 0.6 GO:1904647 response to rotenone(GO:1904647)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.0 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.9 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.9 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.1 1.9 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 0.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.1 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.5 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.6 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.1 0.9 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 0.7 GO:0060174 limb bud formation(GO:0060174)
0.1 0.9 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0035627 ceramide transport(GO:0035627)
0.1 2.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.1 3.7 GO:0097352 autophagosome maturation(GO:0097352)
0.1 1.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 6.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.8 GO:0015866 ADP transport(GO:0015866)
0.1 0.4 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0061364 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.7 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.6 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.9 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 4.1 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.8 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 2.6 GO:0001657 ureteric bud development(GO:0001657)
0.0 1.5 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 2.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0048663 neuron fate commitment(GO:0048663)
0.0 1.2 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 2.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0008542 visual learning(GO:0008542)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.9 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.8 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.5 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.2 3.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 2.1 GO:0005883 neurofilament(GO:0005883)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 3.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 8.7 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 4.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.4 GO:0031526 brush border membrane(GO:0031526)
0.0 1.0 GO:0001533 cornified envelope(GO:0001533)
0.0 2.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.6 GO:0015030 Cajal body(GO:0015030)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 2.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 4.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 4.9 GO:0043209 myelin sheath(GO:0043209)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 3.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.5 6.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.5 4.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 2.4 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.4 1.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 2.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.3 1.2 GO:0008431 vitamin E binding(GO:0008431)
0.3 0.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 2.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 5.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 2.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 4.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.6 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.9 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 4.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 1.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 2.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.2 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.8 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.8 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 3.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 10.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0016015 morphogen activity(GO:0016015)
0.0 2.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.3 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 5.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 4.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.6 GO:0051117 ATPase binding(GO:0051117)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 3.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 10.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 2.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 4.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 2.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 6.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.5 REACTOME OPSINS Genes involved in Opsins
0.1 2.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.7 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 8.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 7.8 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives