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Illumina Body Map 2: averaged replicates

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Results for PRDM1

Z-value: 2.34

Motif logo

Transcription factors associated with PRDM1

Gene Symbol Gene ID Gene Info
ENSG00000057657.10 PRDM1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v2_chr6_+_106535455_106535637-0.125.2e-01Click!

Activity profile of PRDM1 motif

Sorted Z-values of PRDM1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_34710066 8.36 ENST00000378792.1
ENST00000259607.2
CCL21
chemokine (C-C motif) ligand 21
chr10_-_44880491 7.52 ENST00000374426.2
ENST00000395795.4
ENST00000395794.2
ENST00000374429.2
ENST00000395793.3
ENST00000343575.6
CXCL12
chemokine (C-X-C motif) ligand 12
chr6_-_112575912 7.19 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr6_-_112575687 6.96 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr6_-_112575758 6.78 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr4_-_100242549 6.40 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr2_+_239756671 6.17 ENST00000448943.2
TWIST2
twist family bHLH transcription factor 2
chr15_-_37393406 5.76 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr5_+_92919043 4.79 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_+_134203273 4.67 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr6_-_112575838 4.49 ENST00000455073.1
LAMA4
laminin, alpha 4
chr9_+_137533615 4.41 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr3_+_8543533 4.35 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr6_-_29527702 4.33 ENST00000377050.4
UBD
ubiquitin D
chr10_-_131762105 4.15 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr11_+_46402583 4.05 ENST00000359803.3
MDK
midkine (neurite growth-promoting factor 2)
chr3_-_168864427 3.95 ENST00000468789.1
MECOM
MDS1 and EVI1 complex locus
chr21_-_40033618 3.79 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr3_+_8543561 3.72 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr8_+_134203303 3.70 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr6_+_127439749 3.67 ENST00000356698.4
RSPO3
R-spondin 3
chr11_+_46402482 3.66 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr3_+_8543393 3.65 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr9_+_18474098 3.55 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr11_+_46402744 3.48 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr22_-_30642782 3.44 ENST00000249075.3
LIF
leukemia inhibitory factor
chr1_-_44497024 3.13 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_+_46402297 3.06 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr7_+_134464414 3.00 ENST00000361901.2
CALD1
caldesmon 1
chr7_+_134464376 3.00 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr4_+_15376165 2.99 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_+_69240302 2.68 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr1_-_44497118 2.49 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr12_-_71003568 2.46 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_-_149375783 2.46 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr2_+_69240415 2.43 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chrX_+_114874727 2.39 ENST00000543070.1
PLS3
plastin 3
chr6_+_118869452 2.33 ENST00000357525.5
PLN
phospholamban
chr8_+_97506033 2.27 ENST00000518385.1
SDC2
syndecan 2
chr1_+_212782012 2.25 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr1_+_199996733 2.19 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr8_-_54436491 2.19 ENST00000426023.1
RP11-400K9.4
RP11-400K9.4
chr1_+_199996702 2.07 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr9_+_18474163 2.05 ENST00000380566.4
ADAMTSL1
ADAMTS-like 1
chr7_+_15728003 2.05 ENST00000442176.1
AC005550.4
AC005550.4
chr22_-_30642728 2.04 ENST00000403987.3
LIF
leukemia inhibitory factor
chr2_+_234526272 1.98 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr4_+_186990298 1.96 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr9_+_18474204 1.95 ENST00000276935.6
ADAMTSL1
ADAMTS-like 1
chr13_+_102104980 1.92 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr19_-_43032532 1.86 ENST00000403461.1
ENST00000352591.5
ENST00000358394.3
ENST00000403444.3
ENST00000308072.4
ENST00000599389.1
ENST00000351134.3
ENST00000161559.6
CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr7_-_122526499 1.86 ENST00000412584.2
CADPS2
Ca++-dependent secretion activator 2
chr8_+_39770803 1.85 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr15_-_37392086 1.82 ENST00000561208.1
MEIS2
Meis homeobox 2
chr10_+_18429606 1.79 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_167275991 1.79 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_+_110453203 1.78 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr4_-_100140331 1.74 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
ADH6
alcohol dehydrogenase 6 (class V)
chr6_+_152011628 1.73 ENST00000404742.1
ENST00000440973.1
ESR1
estrogen receptor 1
chr1_+_110453608 1.72 ENST00000369801.1
CSF1
colony stimulating factor 1 (macrophage)
chrX_-_154563889 1.71 ENST00000369449.2
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr1_+_110453109 1.70 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr2_-_36779411 1.64 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr2_+_234590556 1.61 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr15_+_71184931 1.60 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr6_-_105584560 1.58 ENST00000336775.5
BVES
blood vessel epicardial substance
chr10_+_18429671 1.58 ENST00000282343.8
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_+_110453514 1.58 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr20_+_6748311 1.57 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr9_+_133259836 1.50 ENST00000455439.2
HMCN2
hemicentin 2
chr3_-_46000064 1.47 ENST00000433878.1
FYCO1
FYVE and coiled-coil domain containing 1
chr6_-_167276033 1.46 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr22_-_36556821 1.43 ENST00000531095.1
ENST00000397293.2
ENST00000349314.2
APOL3
apolipoprotein L, 3
chr2_+_234545092 1.43 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr6_+_26156551 1.40 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr1_+_110453462 1.33 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr7_-_41742697 1.31 ENST00000242208.4
INHBA
inhibin, beta A
chr13_+_24144509 1.27 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr9_+_135457530 1.26 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr10_-_35104185 1.25 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr11_+_71709938 1.23 ENST00000393705.4
ENST00000337131.5
ENST00000531053.1
ENST00000404792.1
IL18BP
interleukin 18 binding protein
chr3_-_46000146 1.20 ENST00000438446.1
FYCO1
FYVE and coiled-coil domain containing 1
chr3_-_64431058 1.14 ENST00000564377.1
PRICKLE2
prickle homolog 2 (Drosophila)
chr16_-_88851618 1.12 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr15_+_71185148 1.11 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr14_-_69262947 1.11 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr19_+_24009879 1.08 ENST00000354585.4
RPSAP58
ribosomal protein SA pseudogene 58
chr19_+_34287174 1.07 ENST00000587559.1
ENST00000588637.1
KCTD15
potassium channel tetramerization domain containing 15
chr13_-_33924755 1.04 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_57505121 0.99 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_+_71710648 0.98 ENST00000260049.5
IL18BP
interleukin 18 binding protein
chr5_+_73109339 0.98 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr4_+_147145709 0.96 ENST00000504313.1
RP11-6L6.2
Uncharacterized protein
chr2_+_231191875 0.93 ENST00000444636.1
ENST00000415673.2
ENST00000243810.6
ENST00000396563.4
SP140L
SP140 nuclear body protein-like
chr12_-_120763739 0.92 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr14_-_69262916 0.91 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr17_-_79818354 0.90 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr6_-_105585022 0.90 ENST00000314641.5
BVES
blood vessel epicardial substance
chr11_+_64008525 0.88 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr5_-_66942617 0.87 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr20_-_57089934 0.86 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr11_+_71710973 0.86 ENST00000393707.4
IL18BP
interleukin 18 binding protein
chr6_-_154831779 0.85 ENST00000607772.1
CNKSR3
CNKSR family member 3
chr14_-_69262789 0.85 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr3_-_4793274 0.85 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr17_+_41158742 0.84 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr13_+_24144796 0.84 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr2_+_234545148 0.83 ENST00000373445.1
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr16_+_20685815 0.82 ENST00000561584.1
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr2_+_231280908 0.81 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr11_+_64008443 0.81 ENST00000309366.4
FKBP2
FK506 binding protein 2, 13kDa
chrX_-_139015153 0.79 ENST00000370557.1
ATP11C
ATPase, class VI, type 11C
chr4_+_152020789 0.78 ENST00000512690.1
ENST00000508783.1
ENST00000512797.1
ENST00000507327.1
ENST00000515792.1
ENST00000506126.1
RPS3A
ribosomal protein S3A
chr1_+_2985726 0.77 ENST00000511072.1
ENST00000378398.3
ENST00000441472.2
ENST00000442529.2
PRDM16
PR domain containing 16
chr1_+_164600184 0.76 ENST00000482110.1
PBX1
pre-B-cell leukemia homeobox 1
chr14_-_69263043 0.74 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr8_-_79717163 0.72 ENST00000520269.1
IL7
interleukin 7
chr6_+_130339710 0.71 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr4_+_146403912 0.71 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr7_+_143747461 0.70 ENST00000408906.2
OR2A5
olfactory receptor, family 2, subfamily A, member 5
chr19_+_13106383 0.70 ENST00000397661.2
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_152020715 0.68 ENST00000274065.4
RPS3A
ribosomal protein S3A
chr4_+_152020736 0.68 ENST00000509736.1
ENST00000505243.1
ENST00000514682.1
ENST00000322686.6
ENST00000503002.1
RPS3A
ribosomal protein S3A
chr3_-_49851313 0.67 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr10_+_62538089 0.65 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr10_-_81203972 0.63 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr1_+_215747118 0.62 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr15_-_96607616 0.62 ENST00000558860.1
RP11-236L14.1
RP11-236L14.1
chr2_+_231280954 0.62 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr1_+_2487631 0.60 ENST00000409119.1
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr2_-_202508169 0.59 ENST00000409883.2
TMEM237
transmembrane protein 237
chr1_+_207262881 0.59 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr12_-_57504975 0.59 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr6_-_10412600 0.58 ENST00000379608.3
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_+_53659746 0.57 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr12_-_50561075 0.57 ENST00000422340.2
ENST00000317551.6
CERS5
ceramide synthase 5
chr19_+_34287751 0.56 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr9_-_117568365 0.54 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr8_+_77593474 0.54 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr10_-_21661870 0.54 ENST00000433460.1
RP11-275N1.1
RP11-275N1.1
chr2_-_70475586 0.53 ENST00000416149.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr10_+_62538248 0.51 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr3_+_119013185 0.51 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr12_+_6561190 0.50 ENST00000544021.1
ENST00000266556.7
TAPBPL
TAP binding protein-like
chr17_-_26695013 0.50 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr4_-_146859787 0.50 ENST00000508784.1
ZNF827
zinc finger protein 827
chr8_+_9009202 0.47 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr8_-_9009079 0.47 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr5_+_140430979 0.45 ENST00000306549.3
PCDHB1
protocadherin beta 1
chr8_-_23540402 0.45 ENST00000523261.1
ENST00000380871.4
NKX3-1
NK3 homeobox 1
chr21_+_22370717 0.43 ENST00000284894.7
NCAM2
neural cell adhesion molecule 2
chr1_-_205325994 0.42 ENST00000491471.1
KLHDC8A
kelch domain containing 8A
chr7_-_111424506 0.42 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr7_+_95401851 0.42 ENST00000447467.2
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr7_-_47621229 0.41 ENST00000434451.1
TNS3
tensin 3
chr6_-_9933500 0.40 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr3_+_69915385 0.40 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr17_-_26694979 0.39 ENST00000438614.1
VTN
vitronectin
chr5_+_86563636 0.38 ENST00000274376.6
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr7_-_86849025 0.37 ENST00000257637.3
TMEM243
transmembrane protein 243, mitochondrial
chr17_+_7211656 0.37 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr14_-_21490958 0.36 ENST00000554104.1
NDRG2
NDRG family member 2
chr1_-_205326161 0.36 ENST00000367156.3
ENST00000606887.1
ENST00000607173.1
KLHDC8A
kelch domain containing 8A
chr7_-_111424462 0.35 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr12_-_106641728 0.35 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr9_+_133454943 0.33 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr2_-_64246206 0.32 ENST00000409558.4
ENST00000272322.4
VPS54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr8_-_56986768 0.32 ENST00000523936.1
RPS20
ribosomal protein S20
chr17_+_6659354 0.32 ENST00000574907.1
XAF1
XIAP associated factor 1
chr8_-_142012169 0.31 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr7_-_78400364 0.30 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr10_+_91589309 0.28 ENST00000448490.1
LINC00865
long intergenic non-protein coding RNA 865
chr3_-_44552094 0.28 ENST00000436261.1
ZNF852
zinc finger protein 852
chr6_-_138820624 0.28 ENST00000343505.5
NHSL1
NHS-like 1
chr1_-_205326022 0.26 ENST00000367155.3
KLHDC8A
kelch domain containing 8A
chr1_+_2985760 0.26 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16
PR domain containing 16
chr5_+_76506706 0.24 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B
phosphodiesterase 8B
chr6_-_32811771 0.24 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr5_-_93447333 0.24 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr18_-_47017956 0.23 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr1_+_199996859 0.23 ENST00000447034.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_-_57232525 0.22 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2
spindle and kinetochore associated complex subunit 2
chr4_+_142557717 0.22 ENST00000320650.4
ENST00000296545.7
IL15
interleukin 15
chr10_+_91589261 0.21 ENST00000448963.1
LINC00865
long intergenic non-protein coding RNA 865
chr1_-_111746966 0.19 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr15_-_56209306 0.19 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
chr1_-_161014731 0.19 ENST00000368020.1
USF1
upstream transcription factor 1
chr22_+_39417118 0.18 ENST00000216099.8
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr3_+_69915363 0.18 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr14_+_24605389 0.17 ENST00000382708.3
ENST00000561435.1
PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr20_-_18774614 0.16 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chr5_-_149380698 0.14 ENST00000296736.3
TIGD6
tigger transposable element derived 6
chr6_+_57182400 0.14 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr11_-_96076334 0.14 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr4_-_140544386 0.13 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr6_-_121655552 0.12 ENST00000275159.6
TBC1D32
TBC1 domain family, member 32
chr11_+_128563652 0.12 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr9_+_84304628 0.12 ENST00000437181.1
RP11-154D17.1
RP11-154D17.1
chr22_+_39436862 0.11 ENST00000381565.2
ENST00000452957.2
APOBEC3F
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr21_+_17909594 0.11 ENST00000441820.1
ENST00000602280.1
LINC00478
long intergenic non-protein coding RNA 478

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0035759 mesangial cell-matrix adhesion(GO:0035759) regulation of dendritic cell dendrite assembly(GO:2000547)
2.4 14.2 GO:0030421 defecation(GO:0030421)
1.9 5.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.7 5.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.6 8.1 GO:1903971 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.5 7.5 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
1.5 4.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.1 5.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.8 2.5 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.8 2.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.7 2.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.7 3.6 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.6 1.9 GO:0043317 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.5 3.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.5 7.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.5 5.8 GO:0051552 flavone metabolic process(GO:0051552)
0.5 1.6 GO:0060129 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.5 4.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.5 2.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.5 1.8 GO:0036269 swimming behavior(GO:0036269)
0.4 1.3 GO:0060279 positive regulation of ovulation(GO:0060279)
0.4 3.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 4.3 GO:0070842 aggresome assembly(GO:0070842)
0.4 8.1 GO:0006069 ethanol oxidation(GO:0006069)
0.4 11.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 2.3 GO:0008218 bioluminescence(GO:0008218)
0.3 1.6 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 2.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.2 0.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 1.4 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 3.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 1.0 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.5 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.2 1.2 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.2 1.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.7 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 2.5 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.8 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 25.4 GO:0045995 regulation of embryonic development(GO:0045995)
0.1 3.1 GO:1900115 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.5 GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.1 4.0 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.5 GO:0003409 optic cup structural organization(GO:0003409)
0.1 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 6.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 2.1 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.9 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 7.6 GO:0008542 visual learning(GO:0008542) pancreas development(GO:0031016)
0.1 1.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.2 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.6 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0031053 osteoblast fate commitment(GO:0002051) primary miRNA processing(GO:0031053)
0.0 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 1.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.9 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 5.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.7 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.6 GO:0030111 regulation of Wnt signaling pathway(GO:0030111)
0.0 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.6 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 8.4 GO:0001558 regulation of cell growth(GO:0001558)
0.0 7.5 GO:0006936 muscle contraction(GO:0006936)
0.0 1.3 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0005588 collagen type V trimer(GO:0005588)
1.2 8.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 2.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.5 25.4 GO:0005605 basal lamina(GO:0005605)
0.4 1.3 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 6.0 GO:0030478 actin cap(GO:0030478)
0.3 1.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 1.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 3.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 6.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.7 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.4 GO:0030870 Mre11 complex(GO:0030870)
0.1 2.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.0 GO:0036020 endolysosome membrane(GO:0036020)
0.1 5.4 GO:0016235 aggresome(GO:0016235)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 0.3 GO:0000938 GARP complex(GO:0000938)
0.1 1.9 GO:0031528 microvillus membrane(GO:0031528)
0.1 3.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 31.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.7 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 5.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 3.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 2.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.7 GO:0032432 actin filament bundle(GO:0032432)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 1.7 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.4 5.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.0 3.1 GO:0042007 interleukin-18 binding(GO:0042007)
1.0 8.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.9 8.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.5 4.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 7.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 1.8 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.4 3.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 2.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.4 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.2 29.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 8.4 GO:0008009 chemokine activity(GO:0008009)
0.2 1.7 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.2 8.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 6.0 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 1.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 5.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.3 GO:0070628 proteasome binding(GO:0070628)
0.1 3.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.9 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0004882 androgen receptor activity(GO:0004882)
0.1 18.3 GO:0008201 heparin binding(GO:0008201)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 2.5 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.8 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 2.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 23.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.1 1.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 7.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.1 GO:0005518 collagen binding(GO:0005518)
0.0 3.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 3.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 2.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 7.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 22.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.3 25.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.2 8.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 7.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 3.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 7.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 5.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 14.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 3.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 7.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 2.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 10.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 6.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 3.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins