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Illumina Body Map 2: averaged replicates

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Results for RAD21_SMC3

Z-value: 1.75

Motif logo

Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
ENSG00000164754.8 RAD21
ENSG00000108055.9 SMC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAD21hg19_v2_chr8_-_117886563_117886605-0.173.5e-01Click!
SMC3hg19_v2_chr10_+_112327425_1123275160.096.2e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_22697537 3.55 ENST00000427632.2
IGLV9-49
immunoglobulin lambda variable 9-49
chr22_+_22735135 3.53 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr22_+_22786288 3.38 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr8_-_27850180 3.31 ENST00000380385.2
ENST00000301906.4
ENST00000354914.3
SCARA5
scavenger receptor class A, member 5 (putative)
chr22_+_22764088 3.24 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr22_+_23040274 3.04 ENST00000390306.2
IGLV2-23
immunoglobulin lambda variable 2-23
chr22_+_22723969 2.97 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr2_+_114737472 2.95 ENST00000420161.1
AC110769.3
AC110769.3
chr14_+_94405901 2.88 ENST00000557646.1
RP11-131H24.4
Uncharacterized protein
chr8_-_27850141 2.72 ENST00000524352.1
SCARA5
scavenger receptor class A, member 5 (putative)
chr17_+_1958388 2.51 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr14_-_75079026 2.48 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr7_-_27219849 2.46 ENST00000396344.4
HOXA10
homeobox A10
chr11_+_1897697 2.40 ENST00000432093.1
LSP1
lymphocyte-specific protein 1
chr19_+_48216600 2.36 ENST00000263277.3
ENST00000538399.1
EHD2
EH-domain containing 2
chr22_+_22550113 2.36 ENST00000390285.3
IGLV6-57
immunoglobulin lambda variable 6-57
chr10_-_76868931 2.34 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr7_+_142334156 2.33 ENST00000390394.3
TRBV20-1
T cell receptor beta variable 20-1
chr17_-_48277552 2.26 ENST00000507689.1
COL1A1
collagen, type I, alpha 1
chr10_+_17272608 2.25 ENST00000421459.2
VIM
vimentin
chr14_+_22337014 2.22 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr14_-_75079294 2.21 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr22_+_22749343 2.20 ENST00000390298.2
IGLV7-43
immunoglobulin lambda variable 7-43
chr16_+_55357672 2.17 ENST00000290552.7
IRX6
iroquois homeobox 6
chr14_+_22386325 2.10 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr7_-_38394118 2.06 ENST00000390345.2
TRGV4
T cell receptor gamma variable 4
chr19_-_55652290 2.05 ENST00000589745.1
TNNT1
troponin T type 1 (skeletal, slow)
chr16_-_15950868 2.04 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11
myosin, heavy chain 11, smooth muscle
chr14_+_22356029 2.02 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr14_+_22362613 2.01 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chr14_+_22446680 1.99 ENST00000390443.3
TRAV8-6
T cell receptor alpha variable 8-6
chr14_+_52118576 1.98 ENST00000395718.2
ENST00000344768.5
FRMD6
FERM domain containing 6
chr14_+_22309368 1.98 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr15_-_64338521 1.95 ENST00000457488.1
ENST00000558069.1
DAPK2
death-associated protein kinase 2
chr10_-_30024716 1.93 ENST00000375398.2
ENST00000375400.3
SVIL
supervillin
chr6_-_41703296 1.85 ENST00000373033.1
TFEB
transcription factor EB
chr14_+_22265444 1.83 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr16_-_49891694 1.83 ENST00000562520.1
ZNF423
zinc finger protein 423
chr14_+_22465771 1.81 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr19_-_55653259 1.78 ENST00000593194.1
TNNT1
troponin T type 1 (skeletal, slow)
chr1_+_28844778 1.72 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr14_+_22217447 1.72 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr10_+_104154229 1.70 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_28844648 1.68 ENST00000373832.1
ENST00000373831.3
RCC1
regulator of chromosome condensation 1
chr9_-_22009241 1.65 ENST00000380142.4
CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr21_-_44846999 1.63 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr6_+_138188351 1.62 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_-_65359947 1.61 ENST00000597463.1
AP001362.1
Uncharacterized protein
chr19_+_49977466 1.60 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr7_-_27219632 1.60 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr14_+_81421710 1.53 ENST00000342443.6
TSHR
thyroid stimulating hormone receptor
chr10_-_15762124 1.47 ENST00000378076.3
ITGA8
integrin, alpha 8
chr12_-_7245152 1.46 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr12_-_7245018 1.44 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr10_+_99332198 1.43 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr5_+_54455946 1.43 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
GPX8
glutathione peroxidase 8 (putative)
chr22_+_23063100 1.41 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr3_-_128212016 1.41 ENST00000498200.1
ENST00000341105.2
GATA2
GATA binding protein 2
chr19_-_49496557 1.40 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr12_-_7245125 1.39 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr19_-_4400415 1.38 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1
chr14_+_81421355 1.36 ENST00000541158.2
TSHR
thyroid stimulating hormone receptor
chr15_-_79103757 1.36 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr7_-_100171270 1.36 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr12_-_7245080 1.35 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr1_-_186344802 1.35 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr14_+_23305760 1.34 ENST00000311852.6
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr3_-_142607740 1.33 ENST00000485766.1
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr2_+_90108504 1.32 ENST00000390271.2
IGKV6D-41
immunoglobulin kappa variable 6D-41 (non-functional)
chr5_-_44388899 1.32 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr10_-_6019984 1.31 ENST00000525219.2
IL15RA
interleukin 15 receptor, alpha
chr17_+_45810594 1.30 ENST00000177694.1
TBX21
T-box 21
chr5_+_148521454 1.30 ENST00000508983.1
ABLIM3
actin binding LIM protein family, member 3
chr18_+_43753500 1.30 ENST00000587591.1
ENST00000588730.1
C18orf25
chromosome 18 open reading frame 25
chr14_+_22508822 1.29 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr17_-_8868991 1.27 ENST00000447110.1
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr4_-_164253738 1.27 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr19_-_6481759 1.26 ENST00000588421.1
DENND1C
DENN/MADD domain containing 1C
chr22_+_22936998 1.26 ENST00000390303.2
IGLV3-32
immunoglobulin lambda variable 3-32 (non-functional)
chr22_+_19744226 1.26 ENST00000332710.4
ENST00000329705.7
ENST00000359500.3
TBX1
T-box 1
chr9_-_134615443 1.26 ENST00000372195.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr10_-_76868866 1.24 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr14_+_22236722 1.23 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6
chr2_-_232571621 1.23 ENST00000595658.1
MGC4771
MGC4771
chr9_-_94712434 1.21 ENST00000375708.3
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr14_+_52118694 1.21 ENST00000554778.1
FRMD6
FERM domain containing 6
chr17_+_72199721 1.21 ENST00000439590.2
ENST00000311111.6
ENST00000584577.1
ENST00000534490.1
ENST00000528433.2
ENST00000533498.1
RPL38
ribosomal protein L38
chr7_+_89783689 1.20 ENST00000297205.2
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr10_+_99332529 1.19 ENST00000455090.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr14_+_22788560 1.18 ENST00000390468.1
TRAV41
T cell receptor alpha variable 41
chr4_+_75858318 1.17 ENST00000307428.7
PARM1
prostate androgen-regulated mucin-like protein 1
chr14_+_23305783 1.17 ENST00000547279.1
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr1_+_93297622 1.17 ENST00000315741.5
RPL5
ribosomal protein L5
chr17_+_42427826 1.17 ENST00000586443.1
GRN
granulin
chr6_+_138188378 1.16 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188551 1.16 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_-_120638902 1.16 ENST00000551150.1
ENST00000313104.5
ENST00000547191.1
ENST00000546989.1
ENST00000392514.4
ENST00000228306.4
ENST00000550856.1
RPLP0
ribosomal protein, large, P0
chr12_-_120703523 1.15 ENST00000267257.7
ENST00000228307.7
ENST00000424649.2
PXN
paxillin
chr16_-_69788816 1.15 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_-_75426826 1.13 ENST00000305249.5
TACR1
tachykinin receptor 1
chr5_+_137688285 1.13 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr9_+_116917807 1.12 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr8_-_48651648 1.12 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr5_-_146833485 1.12 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr19_+_4791722 1.11 ENST00000269856.3
FEM1A
fem-1 homolog a (C. elegans)
chr15_+_63340775 1.11 ENST00000559281.1
ENST00000317516.7
TPM1
tropomyosin 1 (alpha)
chr16_-_11350036 1.11 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr10_-_76995769 1.10 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr4_+_75858290 1.09 ENST00000513238.1
PARM1
prostate androgen-regulated mucin-like protein 1
chr11_-_117103208 1.09 ENST00000320934.3
ENST00000530269.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr10_+_102759045 1.09 ENST00000370220.1
LZTS2
leucine zipper, putative tumor suppressor 2
chr9_-_134615326 1.08 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr19_+_5690297 1.08 ENST00000582463.1
ENST00000579446.1
ENST00000394580.2
RPL36
ribosomal protein L36
chr19_+_5690207 1.07 ENST00000347512.3
RPL36
ribosomal protein L36
chr2_+_69240511 1.07 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr19_-_35626104 1.06 ENST00000310123.3
ENST00000392225.3
LGI4
leucine-rich repeat LGI family, member 4
chr4_-_41884620 1.06 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr10_-_76995675 1.05 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_+_185703513 1.03 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr19_-_41859814 1.03 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr2_+_234263120 1.02 ENST00000264057.2
ENST00000427930.1
DGKD
diacylglycerol kinase, delta 130kDa
chr6_-_41673552 1.02 ENST00000419574.1
ENST00000445214.1
TFEB
transcription factor EB
chr16_-_89008211 1.01 ENST00000569464.1
ENST00000569443.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr1_+_37940153 1.01 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr20_+_30102231 1.00 ENST00000335574.5
ENST00000340852.5
ENST00000398174.3
ENST00000376127.3
ENST00000344042.5
HM13
histocompatibility (minor) 13
chr17_-_40833858 1.00 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr2_-_89459813 1.00 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr19_-_19754404 1.00 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr2_+_69240302 0.99 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr19_-_19051927 0.99 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr22_-_22292934 0.99 ENST00000538191.1
ENST00000424647.1
ENST00000407142.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr19_-_19754354 0.98 ENST00000587238.1
GMIP
GEM interacting protein
chr3_+_50192457 0.97 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_131113609 0.96 ENST00000347849.3
PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr6_+_160769399 0.96 ENST00000392145.1
SLC22A3
solute carrier family 22 (organic cation transporter), member 3
chr15_+_75074410 0.95 ENST00000439220.2
CSK
c-src tyrosine kinase
chr5_+_148521381 0.95 ENST00000504238.1
ABLIM3
actin binding LIM protein family, member 3
chr8_-_145550337 0.95 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr8_+_17434689 0.94 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr3_+_50192499 0.94 ENST00000413852.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr5_-_146833222 0.92 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr2_+_131113580 0.91 ENST00000175756.5
PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr7_-_38398721 0.90 ENST00000390346.2
TRGV3
T cell receptor gamma variable 3
chr1_+_93297582 0.90 ENST00000370321.3
RPL5
ribosomal protein L5
chr9_+_129622904 0.90 ENST00000319119.4
ZBTB34
zinc finger and BTB domain containing 34
chr6_+_35310312 0.89 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD
peroxisome proliferator-activated receptor delta
chr6_+_33359582 0.88 ENST00000450504.1
KIFC1
kinesin family member C1
chr14_+_22293618 0.88 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr18_-_26941900 0.87 ENST00000577674.1
CTD-2515C13.2
CTD-2515C13.2
chr16_+_48657361 0.87 ENST00000565072.1
RP11-42I10.1
RP11-42I10.1
chr6_-_32920794 0.86 ENST00000395305.3
ENST00000395303.3
ENST00000374843.4
ENST00000429234.1
HLA-DMA
XXbac-BPG181M17.5
major histocompatibility complex, class II, DM alpha
Uncharacterized protein
chr15_+_75074385 0.86 ENST00000220003.9
CSK
c-src tyrosine kinase
chr12_-_51663959 0.86 ENST00000604188.1
ENST00000398453.3
SMAGP
small cell adhesion glycoprotein
chr4_+_56815102 0.86 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr11_+_65837907 0.86 ENST00000320580.4
PACS1
phosphofurin acidic cluster sorting protein 1
chr7_-_100425112 0.85 ENST00000358173.3
EPHB4
EPH receptor B4
chr1_+_212208919 0.85 ENST00000366991.4
ENST00000542077.1
DTL
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
chr15_+_63340734 0.85 ENST00000560959.1
TPM1
tropomyosin 1 (alpha)
chr11_-_64510409 0.85 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_48807351 0.84 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr17_+_16318850 0.84 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr6_+_35310391 0.84 ENST00000337400.2
ENST00000311565.4
ENST00000540939.1
PPARD
peroxisome proliferator-activated receptor delta
chr17_+_16318909 0.84 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr5_+_148521046 0.83 ENST00000326685.7
ENST00000356541.3
ENST00000309868.7
ABLIM3
actin binding LIM protein family, member 3
chr19_+_56165480 0.83 ENST00000450554.2
U2AF2
U2 small nuclear RNA auxiliary factor 2
chr10_-_101769617 0.83 ENST00000324109.4
ENST00000342239.3
DNMBP
dynamin binding protein
chr2_+_69240415 0.82 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr1_-_17766198 0.81 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr19_-_6481776 0.81 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr17_+_7621045 0.79 ENST00000570791.1
DNAH2
dynein, axonemal, heavy chain 2
chr4_-_120548779 0.79 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr2_-_238305397 0.79 ENST00000409809.1
COL6A3
collagen, type VI, alpha 3
chr11_+_73675873 0.79 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr19_-_33793430 0.79 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_117102768 0.79 ENST00000532301.1
PCSK7
proprotein convertase subtilisin/kexin type 7
chr1_-_139379 0.78 ENST00000423372.3
AL627309.1
Uncharacterized protein
chr19_-_19051993 0.78 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr5_-_146833803 0.77 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr19_-_4791219 0.77 ENST00000598782.1
AC005523.3
AC005523.3
chr5_-_139726181 0.77 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr2_+_90060377 0.77 ENST00000436451.2
IGKV6D-21
immunoglobulin kappa variable 6D-21 (non-functional)
chr7_+_150706010 0.76 ENST00000475017.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr16_+_29127282 0.76 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr9_-_139940608 0.76 ENST00000371601.4
NPDC1
neural proliferation, differentiation and control, 1
chr15_+_92396920 0.74 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr2_-_72375167 0.74 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr8_+_22446763 0.73 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr19_+_1941117 0.73 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr9_-_140317605 0.73 ENST00000479452.1
ENST00000465160.2
EXD3
exonuclease 3'-5' domain containing 3
chr14_+_22433675 0.73 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr8_-_145550571 0.73 ENST00000332324.4
DGAT1
diacylglycerol O-acyltransferase 1
chr11_+_44117219 0.73 ENST00000532479.1
ENST00000527014.1
EXT2
exostosin glycosyltransferase 2
chr12_-_7261772 0.72 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr19_+_58341656 0.72 ENST00000442832.4
ENST00000594901.1
ZNF587B
zinc finger protein 587B
chrX_-_71497148 0.72 ENST00000316084.6
RPS4X
ribosomal protein S4, X-linked
chr10_-_6622258 0.72 ENST00000263125.5
PRKCQ
protein kinase C, theta
chr22_+_23077065 0.72 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr12_-_51663728 0.72 ENST00000603864.1
ENST00000605426.1
SMAGP
small cell adhesion glycoprotein
chr11_-_66103932 0.71 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr9_-_140317676 0.71 ENST00000342129.4
ENST00000340951.4
EXD3
exonuclease 3'-5' domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
1.0 2.9 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.7 2.9 GO:1904588 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.7 2.0 GO:0035981 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.6 2.3 GO:0044691 tooth eruption(GO:0044691)
0.5 2.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.5 2.1 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.4 1.3 GO:0060661 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) secretion by lung epithelial cell involved in lung growth(GO:0061033) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.4 3.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 1.7 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 1.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.4 3.0 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 3.2 GO:0003383 apical constriction(GO:0003383)
0.4 1.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.3 1.0 GO:0052552 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.3 1.0 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 1.4 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.3 1.0 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.3 1.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.3 1.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.3 1.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.3 2.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.3 1.5 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.3 0.9 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.3 2.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 0.8 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.3 0.8 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.3 2.5 GO:1990834 response to odorant(GO:1990834)
0.2 1.8 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 4.3 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.2 1.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) operant conditioning(GO:0035106)
0.2 0.7 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.9 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.2 1.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 1.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.2 GO:0048318 axial mesoderm development(GO:0048318)
0.2 0.6 GO:2000724 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.2 1.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 6.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 0.5 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.2 1.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 0.8 GO:0051541 elastin metabolic process(GO:0051541)
0.2 0.8 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 2.4 GO:0070307 lens fiber cell development(GO:0070307)
0.1 0.6 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.9 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 21.2 GO:0030449 regulation of complement activation(GO:0030449)
0.1 0.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.9 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.5 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 1.1 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.4 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 1.7 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 1.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.7 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 1.0 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.1 0.5 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.1 0.7 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 2.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.1 2.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.1 0.7 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.4 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 1.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 3.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.0 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.2 GO:1903121 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.6 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.9 GO:0071316 cellular response to nicotine(GO:0071316)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:2000283 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 2.8 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.6 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 13.0 GO:0002377 immunoglobulin production(GO:0002377)
0.1 0.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.8 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.5 GO:0060065 uterus development(GO:0060065)
0.1 0.5 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.9 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.1 3.9 GO:0097435 fibril organization(GO:0097435)
0.1 0.1 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.1 0.2 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 1.7 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 1.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.3 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.1 GO:0035989 tendon development(GO:0035989) tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 1.5 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.8 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 1.2 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 1.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 1.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.5 GO:2000344 cellular response to potassium ion(GO:0035865) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 1.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 1.0 GO:0007601 visual perception(GO:0007601) sensory perception of light stimulus(GO:0050953)
0.0 0.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.9 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.0 0.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 1.9 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0035799 ureter maturation(GO:0035799)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 2.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 2.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 5.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 5.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 2.8 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 1.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.7 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 1.7 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 2.5 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0002865 negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865)
0.0 2.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 3.6 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.5 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 1.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.0 0.5 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0060348 bone development(GO:0060348)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 1.3 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 1.1 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.5 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.1 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0072679 thymocyte migration(GO:0072679)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.8 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 1.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 1.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 1.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.9 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.4 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 1.9 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 1.5 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.6 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0005584 collagen type I trimer(GO:0005584)
0.6 1.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.4 1.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 1.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.5 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 2.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.2 3.8 GO:0005861 troponin complex(GO:0005861)
0.1 3.0 GO:0032059 bleb(GO:0032059)
0.1 1.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.4 GO:0035101 FACT complex(GO:0035101)
0.1 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.0 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.8 GO:0089701 U2AF(GO:0089701)
0.1 1.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 1.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.1 1.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 1.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.4 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.0 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 2.9 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.0 GO:0032982 myosin filament(GO:0032982)
0.1 7.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.4 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.8 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0031298 replication fork protection complex(GO:0031298)
0.0 5.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 2.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.7 GO:0042641 actomyosin(GO:0042641)
0.0 2.6 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.3 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 3.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 5.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 1.3 GO:0005874 microtubule(GO:0005874)
0.0 0.2 GO:0030027 lamellipodium(GO:0030027)
0.0 1.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 11.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.9 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 1.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 1.0 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 5.8 GO:0000785 chromatin(GO:0000785)
0.0 0.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.8 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 17.6 GO:0005615 extracellular space(GO:0005615)
0.0 6.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.4 1.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.4 1.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.4 1.7 GO:0001601 peptide YY receptor activity(GO:0001601)
0.4 2.9 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.4 1.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.3 3.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 1.7 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.3 2.2 GO:1990254 keratin filament binding(GO:1990254)
0.3 3.8 GO:0031014 troponin T binding(GO:0031014)
0.3 1.8 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 1.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 0.9 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.2 1.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 3.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 0.6 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 2.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 1.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.0 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.4 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.1 1.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 2.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 2.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.4 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 1.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 29.9 GO:0003823 antigen binding(GO:0003823)
0.1 1.4 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0046977 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.1 0.9 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 1.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 0.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.9 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.5 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.7 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.2 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 6.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 2.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.7 GO:0035198 miRNA binding(GO:0035198)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.0 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 4.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.7 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 1.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 1.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 5.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 1.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 6.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 5.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0016530 metallochaperone activity(GO:0016530)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.7 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 9.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 7.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.5 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.8 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 1.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 4.2 GO:0019838 growth factor binding(GO:0019838)
0.0 0.5 GO:0070001 aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.4 GO:0031701 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 1.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.7 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.3 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 1.8 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0017022 myosin binding(GO:0017022)
0.0 3.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.1 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 6.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.1 PID IFNG PATHWAY IFN-gamma pathway
0.1 4.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.3 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 2.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 3.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.8 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 2.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 2.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 6.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 9.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 2.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.7 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 4.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 9.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 2.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.8 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 1.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.9 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.8 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 4.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.8 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 2.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination