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Illumina Body Map 2: averaged replicates

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Results for RELA

Z-value: 2.60

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
ENSG00000173039.14 RELA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430554_654305790.611.9e-04Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_9913489 9.27 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr4_-_76944621 9.16 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_31550192 7.55 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr2_-_89442621 6.99 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr2_+_219745020 6.74 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr22_-_37545972 6.36 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr19_-_6591113 5.92 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr6_+_138188351 5.89 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr10_+_30723045 5.86 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr6_+_138188378 5.78 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_+_102188272 5.59 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr1_-_186649543 5.50 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr6_+_138188551 5.47 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_+_102188224 5.33 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr10_+_30722866 5.16 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr4_+_74735102 5.14 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr4_-_74864386 5.11 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr10_+_104154229 4.89 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_+_42381173 4.75 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr11_-_5271122 4.37 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr4_-_74904398 4.37 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr19_+_45504688 4.36 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr5_-_149792295 4.35 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_+_37318082 4.18 ENST00000406230.1
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr14_+_103589789 4.14 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr17_-_34207295 4.13 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_+_32605134 4.11 ENST00000343139.5
ENST00000395363.1
ENST00000496318.1
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_42381337 4.08 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr17_-_61776522 4.01 ENST00000582055.1
LIMD2
LIM domain containing 2
chr3_+_101546827 4.00 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr17_-_61777090 3.93 ENST00000578061.1
LIMD2
LIM domain containing 2
chr6_+_32605195 3.90 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_-_76957214 3.84 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_+_201979645 3.76 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_-_17958771 3.66 ENST00000534444.1
JAK3
Janus kinase 3
chr10_+_30723105 3.65 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr6_+_106534192 3.58 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr22_-_37640277 3.47 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_-_76928641 3.45 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr14_+_75988768 3.40 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr9_-_139927462 3.35 ENST00000314412.6
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr14_-_35873856 3.34 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr16_+_50730910 3.26 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr7_+_22766766 3.26 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr17_+_16318850 3.21 ENST00000338560.7
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr1_-_89738528 3.20 ENST00000343435.5
GBP5
guanylate binding protein 5
chr17_+_16318909 3.15 ENST00000577397.1
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr22_-_37640456 3.12 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_+_75988851 3.08 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr1_-_204436344 3.07 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr19_-_47734448 3.07 ENST00000439096.2
BBC3
BCL2 binding component 3
chr4_-_74964904 3.04 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr6_-_32636145 3.02 ENST00000399084.1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr6_+_135502466 2.99 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr19_+_17638059 2.98 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr3_+_137717571 2.91 ENST00000343735.4
CLDN18
claudin 18
chr6_+_31540056 2.91 ENST00000418386.2
LTA
lymphotoxin alpha
chr17_+_40440481 2.87 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr3_-_111852061 2.85 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr2_+_228678550 2.85 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr19_+_45251804 2.85 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr9_+_127054217 2.79 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr4_-_185395191 2.75 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr3_-_156878482 2.74 ENST00000295925.4
CCNL1
cyclin L1
chr19_-_17958832 2.74 ENST00000458235.1
JAK3
Janus kinase 3
chr3_-_156878540 2.73 ENST00000461804.1
CCNL1
cyclin L1
chr12_+_52445191 2.70 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr19_-_7766991 2.69 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr7_-_16844611 2.69 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chrX_-_30595959 2.68 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr6_+_29691056 2.60 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr11_-_128392085 2.59 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr19_+_17638041 2.58 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr5_+_82767284 2.58 ENST00000265077.3
VCAN
versican
chr10_+_104155450 2.57 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_+_143078652 2.55 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr19_-_11688260 2.51 ENST00000590832.1
ACP5
acid phosphatase 5, tartrate resistant
chr6_+_29691198 2.51 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr19_+_35940486 2.51 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr10_+_30723533 2.50 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr19_-_11688447 2.44 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr1_-_202130702 2.43 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr5_+_118604385 2.41 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_143078379 2.40 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr14_+_22573582 2.35 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr6_+_144471643 2.35 ENST00000367568.4
STX11
syntaxin 11
chr7_-_27169801 2.32 ENST00000511914.1
HOXA4
homeobox A4
chr14_+_61789382 2.28 ENST00000555082.1
PRKCH
protein kinase C, eta
chr1_+_201979743 2.26 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr9_-_136344197 2.26 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr3_-_111852128 2.26 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr1_-_202129105 2.25 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_209825674 2.23 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr19_+_10381769 2.20 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr12_-_57504069 2.13 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr11_-_58345569 2.12 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr11_-_75062730 2.11 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr18_+_3252265 2.10 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr17_+_40440094 2.08 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr20_-_45530365 2.08 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr16_+_3096638 2.07 ENST00000336577.4
MMP25
matrix metallopeptidase 25
chr19_-_11688500 2.07 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr3_+_111578027 2.06 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr13_+_108922228 2.03 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr12_-_22487588 2.01 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr10_-_6104253 1.99 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr19_+_41281060 1.99 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr12_-_55375622 1.98 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr1_-_202129704 1.97 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_236030216 1.96 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr4_+_74702214 1.95 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr9_+_127054254 1.91 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr2_-_43453734 1.89 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr2_-_191885686 1.88 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_-_155959853 1.88 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr2_+_201987200 1.87 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_+_38474489 1.85 ENST00000394089.2
ENST00000425707.3
RARA
retinoic acid receptor, alpha
chr1_+_66820058 1.84 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_+_52430894 1.82 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr3_-_158390282 1.81 ENST00000264265.3
LXN
latexin
chr2_+_61108771 1.80 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr4_-_185395672 1.79 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr6_+_29910301 1.76 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr11_+_118754475 1.76 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr7_+_143771275 1.76 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr1_+_111770232 1.73 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr1_+_186649754 1.73 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr1_+_111770278 1.72 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr3_+_111578131 1.72 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr3_+_157154578 1.71 ENST00000295927.3
PTX3
pentraxin 3, long
chr20_-_62203808 1.69 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr11_-_75062829 1.68 ENST00000393505.4
ARRB1
arrestin, beta 1
chr1_+_26869597 1.67 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr6_-_30712313 1.67 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr22_-_19512893 1.67 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr6_-_74231303 1.66 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr4_+_103422499 1.66 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_4852332 1.64 ENST00000572383.1
PFN1
profilin 1
chr11_+_72525353 1.64 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr21_+_34775698 1.62 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr12_-_127256858 1.61 ENST00000542248.1
ENST00000540684.1
LINC00944
long intergenic non-protein coding RNA 944
chr1_+_100818156 1.59 ENST00000336454.3
CDC14A
cell division cycle 14A
chr8_-_101724989 1.59 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_153935983 1.58 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr12_-_127256772 1.58 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr21_+_34775772 1.58 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_42364460 1.57 ENST00000593863.1
RPS19
ribosomal protein S19
chr13_+_108921977 1.54 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr7_+_120629653 1.52 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr4_-_40631859 1.50 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr6_-_74230741 1.48 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr14_+_22984601 1.47 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr19_+_51728316 1.47 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr4_-_174256276 1.47 ENST00000296503.5
HMGB2
high mobility group box 2
chr1_-_153935938 1.46 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr12_+_11802753 1.45 ENST00000396373.4
ETV6
ets variant 6
chr12_-_57023995 1.45 ENST00000549884.1
ENST00000546695.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr19_+_42363917 1.44 ENST00000598742.1
RPS19
ribosomal protein S19
chr5_-_158526693 1.44 ENST00000380654.4
EBF1
early B-cell factor 1
chr5_-_158526756 1.44 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr12_+_7055631 1.43 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_41950342 1.42 ENST00000372587.4
EDN2
endothelin 2
chr6_-_29527702 1.42 ENST00000377050.4
UBD
ubiquitin D
chr5_+_118604439 1.39 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr14_+_22985251 1.39 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr5_-_141338377 1.38 ENST00000510041.1
PCDH12
protocadherin 12
chr12_+_65672702 1.36 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr1_+_156123318 1.36 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_52280173 1.35 ENST00000296487.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr2_+_97202480 1.35 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr19_+_42364313 1.34 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr19_-_11688951 1.33 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant
chr7_-_100881109 1.32 ENST00000308344.5
CLDN15
claudin 15
chr1_+_247579451 1.32 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr1_+_156123359 1.32 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr5_-_150460539 1.31 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr16_+_50775948 1.30 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr1_+_100818009 1.29 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr1_-_161168834 1.29 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr18_-_12884259 1.29 ENST00000353319.4
ENST00000327283.3
PTPN2
protein tyrosine phosphatase, non-receptor type 2
chr15_+_57884117 1.28 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr2_+_233925064 1.28 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr3_+_184033551 1.28 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr3_+_52280220 1.26 ENST00000409502.3
ENST00000323588.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr14_+_103243813 1.26 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr11_-_96076334 1.26 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr5_-_150466692 1.24 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr7_+_120969045 1.24 ENST00000222462.2
WNT16
wingless-type MMTV integration site family, member 16
chr1_+_111770294 1.23 ENST00000474304.2
CHI3L2
chitinase 3-like 2
chrX_-_131353461 1.23 ENST00000370874.1
RAP2C
RAP2C, member of RAS oncogene family
chr8_+_38758737 1.23 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr2_-_109605663 1.23 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr2_+_161993465 1.22 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr1_+_145477060 1.21 ENST00000369308.3
LIX1L
Lix1 homolog (mouse)-like
chr17_-_7590745 1.19 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr18_+_3450161 1.17 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr2_+_97203082 1.16 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr11_+_57508825 1.16 ENST00000534355.1
C11orf31
chromosome 11 open reading frame 31
chr2_+_202047843 1.14 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr1_-_38100491 1.13 ENST00000356545.2
RSPO1
R-spondin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.1 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
2.6 10.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
2.1 6.4 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
1.8 5.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.4 1.4 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
1.3 10.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
1.3 16.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
1.2 7.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
1.2 3.6 GO:1990654 sebum secreting cell proliferation(GO:1990654)
1.2 3.5 GO:1990108 protein linear deubiquitination(GO:1990108)
1.1 3.4 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
1.1 3.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
1.1 4.3 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.1 7.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
1.1 3.2 GO:0072616 interleukin-18 secretion(GO:0072616)
1.0 8.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
1.0 29.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
1.0 3.0 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
1.0 2.9 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.9 2.8 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.9 10.9 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.9 2.6 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.8 2.5 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.8 4.2 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.8 3.3 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.8 3.9 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.7 3.6 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.7 4.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.7 6.9 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.7 2.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.7 2.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.5 2.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.5 2.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.5 4.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.5 2.4 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.5 4.8 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.5 1.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.4 6.7 GO:0048733 sebaceous gland development(GO:0048733)
0.4 2.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.7 GO:0001878 response to yeast(GO:0001878)
0.4 5.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.4 12.2 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.4 5.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.4 3.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 3.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 2.6 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.4 1.8 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.4 2.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 2.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 1.8 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.4 3.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.3 1.7 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.3 6.0 GO:0060056 mammary gland involution(GO:0060056)
0.3 1.0 GO:0090427 activation of meiosis(GO:0090427)
0.3 3.3 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 0.3 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.3 2.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.3 2.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.3 1.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 1.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.3 0.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.1 GO:0000103 sulfate assimilation(GO:0000103)
0.3 4.7 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 3.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 1.3 GO:0032621 interleukin-18 production(GO:0032621)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 4.1 GO:0051601 exocyst localization(GO:0051601)
0.2 0.8 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 28.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.2 1.9 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 0.6 GO:0051685 maintenance of ER location(GO:0051685)
0.2 2.4 GO:0030091 protein repair(GO:0030091)
0.2 1.5 GO:0007296 vitellogenesis(GO:0007296)
0.2 1.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.9 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 7.0 GO:0003094 glomerular filtration(GO:0003094)
0.2 4.4 GO:0015671 oxygen transport(GO:0015671)
0.2 0.5 GO:0032203 telomere formation via telomerase(GO:0032203)
0.2 2.1 GO:0060022 hard palate development(GO:0060022)
0.2 1.9 GO:1903944 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.1 0.9 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 3.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 1.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 2.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.6 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 2.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 2.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 1.6 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:0019933 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.1 4.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 1.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 2.0 GO:0001780 neutrophil homeostasis(GO:0001780)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 1.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.0 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.1 2.3 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.7 GO:0072553 terminal button organization(GO:0072553)
0.1 0.5 GO:0045359 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.9 GO:0048535 lymph node development(GO:0048535)
0.1 7.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 2.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 1.8 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.5 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 1.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 2.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 2.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.3 GO:0033590 response to cobalamin(GO:0033590)
0.1 0.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 4.7 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 6.4 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 3.1 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 1.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.3 GO:0036343 psychomotor behavior(GO:0036343)
0.1 2.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.7 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 4.7 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 1.0 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 4.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 2.5 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.7 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 2.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 3.7 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 0.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.2 GO:0097352 autophagosome maturation(GO:0097352)
0.0 2.8 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.4 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 4.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 1.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 3.8 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 1.4 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.9 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 3.1 GO:1905037 autophagosome organization(GO:1905037)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 5.3 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 1.2 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.4 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 1.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 2.0 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 1.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0008334 histone mRNA metabolic process(GO:0008334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
2.3 7.0 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
1.4 4.2 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
1.3 12.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.3 8.8 GO:0019815 B cell receptor complex(GO:0019815)
0.7 15.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 3.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.6 6.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 6.0 GO:0032584 growth cone membrane(GO:0032584)
0.3 2.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 0.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 1.1 GO:0043291 RAVE complex(GO:0043291)
0.3 4.4 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.0 GO:0031251 PAN complex(GO:0031251)
0.2 2.7 GO:0005610 laminin-5 complex(GO:0005610)
0.2 3.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 0.7 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.2 4.3 GO:0097342 ripoptosome(GO:0097342)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 4.5 GO:0031143 pseudopodium(GO:0031143)
0.1 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 4.1 GO:0000145 exocyst(GO:0000145)
0.1 3.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 1.6 GO:0045180 basal cortex(GO:0045180)
0.1 38.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.3 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 5.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 1.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 6.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 5.5 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 6.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.7 GO:0000125 PCAF complex(GO:0000125)
0.1 2.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 6.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 4.8 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.4 GO:0005861 troponin complex(GO:0005861)
0.1 1.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.5 GO:0097542 ciliary tip(GO:0097542)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 4.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 2.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 5.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0031906 late endosome lumen(GO:0031906)
0.0 1.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 6.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 10.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 32.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.1 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 7.1 GO:0000922 spindle pole(GO:0000922)
0.0 3.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.7 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 4.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 2.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0042641 actomyosin(GO:0042641)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 6.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 25.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.8 19.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
1.7 8.4 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
1.3 3.8 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.1 5.5 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
1.1 20.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.9 2.8 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.9 1.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.9 4.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.8 4.2 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.7 5.1 GO:0046979 TAP2 binding(GO:0046979)
0.7 4.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.6 11.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.6 4.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 3.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 23.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.4 8.4 GO:0008199 ferric iron binding(GO:0008199)
0.4 3.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 16.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.4 1.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 2.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.3 3.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 5.1 GO:0045159 myosin II binding(GO:0045159)
0.3 3.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 17.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 2.6 GO:1990763 arrestin family protein binding(GO:1990763)
0.3 1.5 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.3 1.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 3.1 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.3 2.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 2.7 GO:0019863 IgE binding(GO:0019863)
0.3 4.7 GO:0004568 chitinase activity(GO:0004568)
0.3 1.3 GO:0097677 STAT family protein binding(GO:0097677)
0.2 4.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 3.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 3.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2 4.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 1.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 2.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.7 GO:0001849 complement component C1q binding(GO:0001849)
0.2 8.1 GO:0005109 frizzled binding(GO:0005109)
0.1 1.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 3.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.5 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 4.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.3 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 5.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 2.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.8 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.4 GO:0031014 troponin T binding(GO:0031014)
0.1 1.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.7 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.7 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 5.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.6 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 1.4 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.6 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.9 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 2.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.7 GO:0038191 neuropilin binding(GO:0038191)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 5.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 5.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 8.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 2.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 2.0 GO:0051117 ATPase binding(GO:0051117)
0.0 2.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 21.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 1.6 GO:0035326 enhancer binding(GO:0035326)
0.0 11.5 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.9 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 1.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 5.0 GO:0000149 SNARE binding(GO:0000149)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 2.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 2.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 4.5 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 2.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 23.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 46.9 PID CD40 PATHWAY CD40/CD40L signaling
0.5 8.5 PID IL23 PATHWAY IL23-mediated signaling events
0.3 22.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.3 28.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 4.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 4.2 PID IL5 PATHWAY IL5-mediated signaling events
0.2 5.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 16.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 5.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 7.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 6.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 4.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 7.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 3.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 7.8 PID BCR 5PATHWAY BCR signaling pathway
0.1 3.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 2.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 2.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.7 ST ADRENERGIC Adrenergic Pathway
0.1 1.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 0.7 ST GAQ PATHWAY G alpha q Pathway
0.1 3.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 8.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.3 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 16.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 9.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 2.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.9 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.6 44.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 35.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.4 9.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.4 16.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.4 12.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 8.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.3 12.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.3 8.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 3.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 9.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 8.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 2.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 7.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 11.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 4.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.0 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 3.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 5.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.1 6.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 8.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 2.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 7.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.9 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 4.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 5.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 3.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres