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Illumina Body Map 2: averaged replicates

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Results for RFX3_RFX2

Z-value: 10.18

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Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
RFX3
ENSG00000080298.11 regulatory factor X3
RFX2
ENSG00000087903.8 regulatory factor X2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg19_v2_chr19_-_6199521_61995460.741.4e-06Click!
RFX3hg19_v2_chr9_-_3489428_34894370.602.6e-04Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_109656439 37.05 ENST00000369949.4
C1orf194
chromosome 1 open reading frame 194
chr21_-_43916296 30.70 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr21_-_43916433 29.91 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr1_-_169396666 29.38 ENST00000456107.1
ENST00000367805.3
CCDC181
coiled-coil domain containing 181
chr1_-_169396646 28.04 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr1_-_159869912 22.71 ENST00000368099.4
CCDC19
coiled-coil domain containing 19
chr5_+_34839260 22.51 ENST00000505624.1
TTC23L
tetratricopeptide repeat domain 23-like
chr3_-_167098059 21.68 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX
zinc finger, B-box domain containing
chr17_+_9479944 21.66 ENST00000396219.3
ENST00000352665.5
WDR16
WD repeat domain 16
chr16_+_84178874 20.30 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr17_-_74137374 20.23 ENST00000322957.6
FOXJ1
forkhead box J1
chr10_+_63422695 20.15 ENST00000330194.2
ENST00000389639.3
C10orf107
chromosome 10 open reading frame 107
chr16_+_84178850 19.65 ENST00000334315.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_-_173638976 19.39 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr9_+_124922171 19.34 ENST00000373764.3
ENST00000536616.1
MORN5
MORN repeat containing 5
chr11_-_75379479 19.27 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr2_+_228736321 19.04 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr15_+_71184931 18.40 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr20_-_3762087 18.35 ENST00000379756.3
SPEF1
sperm flagellar 1
chr1_-_118727781 18.31 ENST00000336338.5
SPAG17
sperm associated antigen 17
chr11_-_75379612 18.09 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr17_-_6735035 17.44 ENST00000338694.2
TEKT1
tektin 1
chr8_-_49647791 17.43 ENST00000262103.3
ENST00000523092.1
ENST00000433756.1
EFCAB1
EF-hand calcium binding domain 1
chr12_+_48577366 17.28 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr19_-_57352064 17.27 ENST00000326441.9
ENST00000593695.1
ENST00000599577.1
ENST00000594389.1
ENST00000423103.2
ENST00000598410.1
ENST00000593711.1
ENST00000391708.3
ENST00000221722.5
ENST00000599935.1
PEG3
ZIM2
paternally expressed 3
zinc finger, imprinted 2
chr12_+_85430110 17.27 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr11_+_94245617 17.11 ENST00000542198.1
RP11-867G2.2
long intergenic non-protein coding RNA 1171
chrX_-_48693955 16.86 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr4_-_177116772 16.83 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr17_-_6735012 16.74 ENST00000535086.1
TEKT1
tektin 1
chr6_-_165723088 16.52 ENST00000230301.8
C6orf118
chromosome 6 open reading frame 118
chr15_+_43803143 16.22 ENST00000382031.1
MAP1A
microtubule-associated protein 1A
chr3_-_50383096 16.16 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr1_+_151682909 15.89 ENST00000326413.3
ENST00000442233.2
RIIAD1
AL589765.1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr16_+_57728701 15.66 ENST00000569375.1
ENST00000360716.3
ENST00000569167.1
ENST00000394337.4
ENST00000563126.1
ENST00000336825.8
CCDC135
coiled-coil domain containing 135
chr1_-_154178803 15.57 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr13_+_37005967 15.44 ENST00000440264.1
ENST00000449823.1
CCNA1
cyclin A1
chr4_-_153700864 15.35 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr15_+_71185148 15.29 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr9_+_135285579 15.04 ENST00000343036.2
ENST00000393216.2
C9orf171
chromosome 9 open reading frame 171
chr4_-_76555657 15.00 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr12_+_106994905 14.35 ENST00000357881.4
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr1_+_151693984 14.25 ENST00000479191.1
RIIAD1
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr2_-_130902567 14.21 ENST00000457413.1
ENST00000392984.3
ENST00000409128.1
ENST00000441670.1
ENST00000409943.3
ENST00000409234.3
ENST00000310463.6
CCDC74B
coiled-coil domain containing 74B
chr2_+_120302041 14.17 ENST00000442513.3
ENST00000413369.3
PCDP1
Primary ciliary dyskinesia protein 1
chr3_+_126113734 14.12 ENST00000352312.1
ENST00000393425.1
CCDC37
coiled-coil domain containing 37
chr5_-_149669192 13.91 ENST00000398376.3
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr8_+_144798429 13.53 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
MAPK15
mitogen-activated protein kinase 15
chr6_-_35109080 13.48 ENST00000486638.1
ENST00000505400.1
ENST00000412155.2
ENST00000373979.2
ENST00000507706.1
ENST00000444780.2
ENST00000492680.2
TCP11
t-complex 11, testis-specific
chr2_+_120301997 13.42 ENST00000602047.1
PCDP1
Primary ciliary dyskinesia protein 1
chr1_+_43637996 13.39 ENST00000528956.1
ENST00000529956.1
WDR65
WD repeat domain 65
chr2_+_79740118 13.05 ENST00000496558.1
ENST00000451966.1
CTNNA2
catenin (cadherin-associated protein), alpha 2
chr19_+_54385439 13.03 ENST00000536044.1
ENST00000540413.1
ENST00000263431.3
ENST00000419486.1
PRKCG
protein kinase C, gamma
chr12_+_51818555 12.96 ENST00000453097.2
SLC4A8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr10_+_127585093 12.87 ENST00000368695.1
ENST00000368693.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr19_-_46974741 12.86 ENST00000313683.10
ENST00000602246.1
PNMAL1
paraneoplastic Ma antigen family-like 1
chr11_-_8615488 12.79 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33
serine/threonine kinase 33
chr6_-_43478239 12.68 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr4_-_87515202 12.58 ENST00000502302.1
ENST00000513186.1
MAPK10
mitogen-activated protein kinase 10
chr8_-_101118185 12.38 ENST00000523437.1
RGS22
regulator of G-protein signaling 22
chr18_-_47792851 12.34 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr7_+_48075108 12.17 ENST00000420324.1
ENST00000435376.1
ENST00000430738.1
ENST00000348904.3
ENST00000539619.1
C7orf57
chromosome 7 open reading frame 57
chr11_-_111944704 12.15 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr13_+_31506818 12.09 ENST00000380473.3
TEX26
testis expressed 26
chr11_-_8615687 12.01 ENST00000534493.1
ENST00000422559.2
STK33
serine/threonine kinase 33
chr15_+_82555125 12.01 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr9_-_135754164 12.01 ENST00000298545.3
AK8
adenylate kinase 8
chr5_-_54529415 11.93 ENST00000282572.4
CCNO
cyclin O
chr1_-_6240183 11.90 ENST00000262450.3
ENST00000378021.1
CHD5
chromodomain helicase DNA binding protein 5
chr2_+_27071045 11.88 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr1_+_42928945 11.86 ENST00000428554.2
CCDC30
coiled-coil domain containing 30
chr1_-_183622442 11.85 ENST00000308641.4
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr22_-_39052300 11.84 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr16_+_67840986 11.76 ENST00000561639.1
ENST00000567852.1
ENST00000565148.1
ENST00000388833.3
ENST00000561654.1
ENST00000431934.2
TSNAXIP1
translin-associated factor X interacting protein 1
chr1_+_161068179 11.73 ENST00000368011.4
ENST00000392192.2
KLHDC9
kelch domain containing 9
chr19_-_46974664 11.70 ENST00000438932.2
PNMAL1
paraneoplastic Ma antigen family-like 1
chr15_+_82555169 11.64 ENST00000565432.1
ENST00000427381.2
FAM154B
family with sequence similarity 154, member B
chr3_-_118753716 11.56 ENST00000393775.2
IGSF11
immunoglobulin superfamily, member 11
chr2_-_233792837 11.53 ENST00000373552.4
ENST00000409079.1
NGEF
neuronal guanine nucleotide exchange factor
chr1_+_38022572 11.47 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr17_+_9479971 11.44 ENST00000576499.1
WDR16
WD repeat domain 16
chr5_-_114505624 11.35 ENST00000513154.1
TRIM36
tripartite motif containing 36
chr11_-_8615720 11.32 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr17_-_7108436 11.28 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr16_+_4784458 11.25 ENST00000590191.1
C16orf71
chromosome 16 open reading frame 71
chr6_-_109761707 11.20 ENST00000520723.1
ENST00000518648.1
ENST00000417394.2
PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr11_-_111944895 11.11 ENST00000431456.1
ENST00000280350.4
ENST00000530641.1
PIH1D2
PIH1 domain containing 2
chr3_-_118753626 11.06 ENST00000489689.1
IGSF11
immunoglobulin superfamily, member 11
chr5_-_11589131 10.99 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr17_+_56833184 10.98 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr20_+_20033158 10.98 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
C20orf26
chromosome 20 open reading frame 26
chr5_+_157098534 10.97 ENST00000409999.3
C5orf52
chromosome 5 open reading frame 52
chrX_+_117957741 10.96 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr6_-_35109145 10.95 ENST00000373974.4
ENST00000244645.3
TCP11
t-complex 11, testis-specific
chr16_+_67840668 10.84 ENST00000415766.3
TSNAXIP1
translin-associated factor X interacting protein 1
chr6_-_19804973 10.66 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr1_+_38022513 10.66 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr10_-_25305011 10.60 ENST00000331161.4
ENST00000376363.1
ENKUR
enkurin, TRPC channel interacting protein
chr10_+_124030819 10.55 ENST00000260723.4
ENST00000368994.2
BTBD16
BTB (POZ) domain containing 16
chr8_-_133687813 10.53 ENST00000250173.1
ENST00000519595.1
LRRC6
leucine rich repeat containing 6
chr11_+_111385497 10.50 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
C11orf88
chromosome 11 open reading frame 88
chr2_+_132285406 10.48 ENST00000295171.6
ENST00000409856.3
CCDC74A
coiled-coil domain containing 74A
chr2_-_2334888 10.39 ENST00000428368.2
ENST00000399161.2
MYT1L
myelin transcription factor 1-like
chr8_-_101118210 10.30 ENST00000360863.6
RGS22
regulator of G-protein signaling 22
chr17_+_11501748 10.30 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr10_-_104179682 10.28 ENST00000406432.1
PSD
pleckstrin and Sec7 domain containing
chr5_-_114505591 10.20 ENST00000508894.1
TRIM36
tripartite motif containing 36
chr1_-_21978312 10.10 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr5_-_11588907 10.05 ENST00000513598.1
ENST00000503622.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr16_-_71264558 10.04 ENST00000448089.2
ENST00000393550.2
ENST00000448691.1
ENST00000393567.2
ENST00000321489.5
ENST00000539973.1
ENST00000288168.10
ENST00000545267.1
ENST00000541601.1
ENST00000538248.1
HYDIN
HYDIN, axonemal central pair apparatus protein
chr13_-_25745857 9.99 ENST00000381853.3
AMER2
APC membrane recruitment protein 2
chr19_-_51289436 9.90 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr1_+_20512568 9.86 ENST00000375099.3
UBXN10
UBX domain protein 10
chr3_-_118753566 9.83 ENST00000491903.1
IGSF11
immunoglobulin superfamily, member 11
chr16_+_27078219 9.69 ENST00000418886.1
C16orf82
chromosome 16 open reading frame 82
chr20_+_30467600 9.64 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr17_-_60885645 9.59 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr19_+_58545434 9.58 ENST00000282326.1
ENST00000601162.1
ZSCAN1
zinc finger and SCAN domain containing 1
chr17_-_60885700 9.57 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr17_-_70417365 9.56 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr11_-_66496430 9.55 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr1_+_160051319 9.49 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr2_+_27070964 9.45 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr3_+_119421849 9.44 ENST00000273390.5
ENST00000463700.1
MAATS1
MYCBP-associated, testis expressed 1
chrX_+_85969626 9.39 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr10_+_134973905 9.35 ENST00000304613.3
ENST00000368572.2
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr4_-_87281196 9.32 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr1_-_40157345 9.30 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr6_+_116937636 9.28 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr6_-_24646249 9.24 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319
KIAA0319
chr7_-_45128472 9.18 ENST00000490531.2
NACAD
NAC alpha domain containing
chr19_-_55690758 9.15 ENST00000590851.1
SYT5
synaptotagmin V
chr5_-_132073111 9.14 ENST00000403231.1
KIF3A
kinesin family member 3A
chr8_-_133687778 9.14 ENST00000518642.1
LRRC6
leucine rich repeat containing 6
chr3_-_47324008 9.14 ENST00000425853.1
KIF9
kinesin family member 9
chr11_-_8615507 9.13 ENST00000431279.2
ENST00000418597.1
STK33
serine/threonine kinase 33
chr4_-_87281224 9.12 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr1_-_50489547 9.09 ENST00000371836.1
ENST00000371839.1
ENST00000371838.1
AGBL4
ATP/GTP binding protein-like 4
chr21_+_18885430 9.09 ENST00000356275.6
ENST00000400165.1
ENST00000400169.1
ENST00000306618.10
CXADR
coxsackie virus and adenovirus receptor
chr2_-_187713891 9.02 ENST00000295131.2
ZSWIM2
zinc finger, SWIM-type containing 2
chr17_-_60885659 9.02 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr16_-_30064244 8.97 ENST00000571269.1
ENST00000561666.1
FAM57B
family with sequence similarity 57, member B
chr3_-_27410847 8.90 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10
NIMA-related kinase 10
chr22_+_30752963 8.87 ENST00000445005.1
ENST00000430839.1
CCDC157
coiled-coil domain containing 157
chr21_-_40817645 8.79 ENST00000438404.1
ENST00000358268.2
ENST00000411566.1
ENST00000451131.1
ENST00000418018.1
ENST00000415863.1
ENST00000426783.1
ENST00000288350.3
ENST00000485895.2
ENST00000448288.2
ENST00000456017.1
ENST00000434281.1
LCA5L
Leber congenital amaurosis 5-like
chr1_-_220101944 8.73 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr8_+_85618155 8.72 ENST00000523850.1
ENST00000521376.1
RALYL
RALY RNA binding protein-like
chr13_+_37006398 8.72 ENST00000418263.1
CCNA1
cyclin A1
chr1_-_67390474 8.70 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78
WD repeat domain 78
chr9_-_35812140 8.69 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
SPAG8
sperm associated antigen 8
chr16_-_30022735 8.55 ENST00000564944.1
DOC2A
double C2-like domains, alpha
chr6_-_32119676 8.55 ENST00000211413.5
PRRT1
proline-rich transmembrane protein 1
chrX_-_152160740 8.54 ENST00000361887.5
ENST00000439251.1
ENST00000452693.1
PNMA5
paraneoplastic Ma antigen family member 5
chr2_+_202937972 8.50 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr5_-_110074603 8.48 ENST00000515278.2
TMEM232
transmembrane protein 232
chr13_+_37006421 8.42 ENST00000255465.4
CCNA1
cyclin A1
chr1_+_33546714 8.38 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr1_+_109656719 8.37 ENST00000457623.2
ENST00000529753.1
KIAA1324
KIAA1324
chr9_+_135285430 8.35 ENST00000393215.3
C9orf171
chromosome 9 open reading frame 171
chr6_-_32119877 8.31 ENST00000375152.2
PRRT1
proline-rich transmembrane protein 1
chr2_+_159651821 8.31 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr4_-_156297949 8.28 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr21_+_18885318 8.13 ENST00000400166.1
CXADR
coxsackie virus and adenovirus receptor
chr16_-_30773372 8.10 ENST00000545825.1
ENST00000541260.1
C16orf93
chromosome 16 open reading frame 93
chr11_-_66360548 8.05 ENST00000333861.3
CCDC87
coiled-coil domain containing 87
chr11_+_134201768 8.00 ENST00000535456.2
ENST00000339772.7
GLB1L2
galactosidase, beta 1-like 2
chr3_-_149688896 8.00 ENST00000239940.7
PFN2
profilin 2
chr11_-_119252359 7.99 ENST00000455332.2
USP2
ubiquitin specific peptidase 2
chr7_-_102715172 7.99 ENST00000456695.1
ENST00000455112.2
ENST00000440067.1
FBXL13
F-box and leucine-rich repeat protein 13
chrX_+_119029800 7.97 ENST00000371431.3
ENST00000371423.2
ENST00000371425.4
ENST00000394594.2
AKAP14
A kinase (PRKA) anchor protein 14
chr2_+_232063260 7.97 ENST00000349938.4
ARMC9
armadillo repeat containing 9
chr10_-_135150367 7.95 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
CALY
calcyon neuron-specific vesicular protein
chr7_+_129142320 7.94 ENST00000462322.2
SMKR1
small lysine-rich protein 1
chr19_-_7990991 7.88 ENST00000318978.4
CTXN1
cortexin 1
chr2_+_120302055 7.88 ENST00000598644.1
PCDP1
Primary ciliary dyskinesia protein 1
chr15_+_67547113 7.87 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH
IQ motif containing H
chr7_+_73275483 7.85 ENST00000320531.2
WBSCR28
Williams-Beuren syndrome chromosome region 28
chr1_+_217804661 7.85 ENST00000366933.4
SPATA17
spermatogenesis associated 17
chr5_-_132073210 7.82 ENST00000378735.1
ENST00000378746.4
KIF3A
kinesin family member 3A
chr19_+_58545369 7.76 ENST00000391700.1
ZSCAN1
zinc finger and SCAN domain containing 1
chr11_+_101918153 7.76 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr16_+_29823427 7.72 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr12_+_122356488 7.71 ENST00000397454.2
WDR66
WD repeat domain 66
chr7_+_133812052 7.70 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr1_+_109656579 7.70 ENST00000526264.1
ENST00000369939.3
KIAA1324
KIAA1324
chr1_+_111889212 7.70 ENST00000369737.4
PIFO
primary cilia formation
chr7_-_102715263 7.69 ENST00000379305.3
FBXL13
F-box and leucine-rich repeat protein 13
chr4_+_87515454 7.65 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr8_-_37797621 7.60 ENST00000524298.1
ENST00000307599.4
GOT1L1
glutamic-oxaloacetic transaminase 1-like 1
chr11_-_31391276 7.58 ENST00000452803.1
DCDC1
doublecortin domain containing 1
chr4_+_40751914 7.57 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chr14_+_60386853 7.54 ENST00000570145.1
LRRC9
leucine rich repeat containing 9
chr10_+_103348031 7.54 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
chr19_-_55677920 7.50 ENST00000524407.2
ENST00000526003.1
ENST00000534170.1
DNAAF3
dynein, axonemal, assembly factor 3
chr10_+_22634384 7.44 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
SPAG6
sperm associated antigen 6
chr1_-_36916011 7.40 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr11_-_119252425 7.40 ENST00000260187.2
USP2
ubiquitin specific peptidase 2
chr15_-_71184724 7.37 ENST00000560604.1
THAP10
THAP domain containing 10
chr1_+_15573757 7.37 ENST00000358897.4
ENST00000417793.1
ENST00000375999.3
ENST00000433640.2
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr3_-_118753792 7.33 ENST00000480431.1
IGSF11
immunoglobulin superfamily, member 11

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 24.4 GO:1902490 regulation of sperm capacitation(GO:1902490)
6.7 20.2 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
5.7 28.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
4.7 41.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
4.0 11.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
3.4 10.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
2.9 17.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
2.7 31.9 GO:0036159 inner dynein arm assembly(GO:0036159)
2.6 23.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
2.6 13.0 GO:0032425 positive regulation of mismatch repair(GO:0032425)
2.6 117.6 GO:0035082 axoneme assembly(GO:0035082)
2.5 7.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
2.5 41.8 GO:0060294 cilium movement involved in cell motility(GO:0060294)
2.2 31.0 GO:0007258 JUN phosphorylation(GO:0007258)
2.2 6.5 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
2.1 50.9 GO:0003341 cilium movement(GO:0003341)
2.1 24.8 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.9 7.8 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.6 4.8 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.6 7.9 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
1.4 17.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
1.4 6.9 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
1.3 11.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.3 14.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.3 11.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
1.2 17.9 GO:0035721 intraciliary retrograde transport(GO:0035721)
1.1 9.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
1.1 8.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
1.1 6.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.1 15.9 GO:0044458 motile cilium assembly(GO:0044458)
1.0 4.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
1.0 19.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.0 20.4 GO:0045475 locomotor rhythm(GO:0045475)
1.0 3.0 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
1.0 14.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
1.0 27.8 GO:1904385 cellular response to angiotensin(GO:1904385)
0.9 9.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.9 5.5 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.9 11.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.8 9.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.8 11.6 GO:0006228 UTP biosynthetic process(GO:0006228)
0.8 32.6 GO:0007141 male meiosis I(GO:0007141)
0.8 12.9 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.8 4.7 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.8 1.6 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.8 4.7 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.7 3.7 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.7 9.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.7 28.3 GO:0071801 regulation of podosome assembly(GO:0071801)
0.7 2.1 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.7 14.6 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.6 5.8 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.6 4.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.6 8.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 31.0 GO:0007340 acrosome reaction(GO:0007340)
0.6 5.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.5 4.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.5 2.6 GO:0001757 somite specification(GO:0001757)
0.5 3.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.5 15.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.5 2.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.5 1.9 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.5 16.9 GO:0002021 response to dietary excess(GO:0002021)
0.5 5.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 5.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.5 8.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.4 3.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.4 9.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 1.6 GO:0060166 olfactory pit development(GO:0060166) Harderian gland development(GO:0070384)
0.4 16.7 GO:0021591 ventricular system development(GO:0021591)
0.4 13.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.4 3.9 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.3 7.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 3.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.3 1.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 2.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.3 2.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.3 9.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 9.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.3 3.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.3 2.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.3 4.0 GO:0035768 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.3 4.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.3 5.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 15.4 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.3 1.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 22.8 GO:0015701 bicarbonate transport(GO:0015701)
0.3 10.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 0.8 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.3 17.1 GO:0010107 potassium ion import(GO:0010107)
0.3 12.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 3.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.3 55.8 GO:0048813 dendrite morphogenesis(GO:0048813)
0.3 12.2 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 10.4 GO:0048665 neuron fate specification(GO:0048665)
0.2 0.2 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.2 10.0 GO:0007398 ectoderm development(GO:0007398)
0.2 5.6 GO:0097320 membrane tubulation(GO:0097320)
0.2 11.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 25.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 15.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 5.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.2 1.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.2 2.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.2 1.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 8.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 1.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 12.0 GO:0006739 NADP metabolic process(GO:0006739)
0.2 37.0 GO:0009566 fertilization(GO:0009566)
0.2 11.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.8 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 11.8 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.2 8.9 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.2 0.9 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 31.8 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.2 0.5 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.2 0.7 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.2 23.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 8.5 GO:0008038 neuron recognition(GO:0008038)
0.2 9.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.2 3.7 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.2 4.3 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.2 9.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 2.8 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 2.6 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 8.2 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 2.2 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 2.7 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 7.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 16.0 GO:0007286 spermatid development(GO:0007286)
0.1 8.5 GO:0014047 glutamate secretion(GO:0014047)
0.1 2.9 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.1 1.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 5.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 5.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 2.3 GO:0050773 regulation of dendrite development(GO:0050773)
0.1 9.3 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.1 6.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 3.8 GO:0060996 dendritic spine development(GO:0060996)
0.1 0.3 GO:0006186 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 1.3 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.3 GO:0042245 RNA repair(GO:0042245)
0.1 7.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 25.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 1.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 3.2 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 2.9 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 3.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.5 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 1.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 23.1 GO:0007411 axon guidance(GO:0007411)
0.1 1.5 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 2.0 GO:0070875 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.1 3.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.1 0.5 GO:0048549 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.1 1.7 GO:0030534 adult behavior(GO:0030534)
0.1 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.1 2.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.2 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 5.0 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.1 0.7 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 4.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 2.5 GO:0006970 response to osmotic stress(GO:0006970)
0.1 2.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 1.7 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 3.9 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 1.4 GO:0032026 response to magnesium ion(GO:0032026)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 1.7 GO:1900744 regulation of p38MAPK cascade(GO:1900744)
0.0 1.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 6.5 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 4.4 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 4.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 16.9 GO:0007283 spermatogenesis(GO:0007283)
0.0 1.1 GO:0016358 dendrite development(GO:0016358)
0.0 0.2 GO:0046782 regulation of viral transcription(GO:0046782) positive regulation of viral transcription(GO:0050434)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 3.6 GO:0022900 electron transport chain(GO:0022900)
0.0 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.9 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 1.1 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 3.1 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.5 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.9 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 1.2 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 2.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 2.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 1.3 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 7.7 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0071481 cellular response to X-ray(GO:0071481)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:1990716 axonemal central apparatus(GO:1990716)
8.8 26.4 GO:0001534 radial spoke(GO:0001534)
8.7 69.7 GO:0002177 manchette(GO:0002177)
6.5 32.6 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
4.3 60.6 GO:0072687 meiotic spindle(GO:0072687)
4.2 17.0 GO:0016939 kinesin II complex(GO:0016939)
2.9 11.5 GO:0097224 sperm connecting piece(GO:0097224)
2.4 7.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
2.3 11.7 GO:0005879 axonemal microtubule(GO:0005879)
1.5 9.1 GO:1990769 proximal neuron projection(GO:1990769)
1.4 24.9 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
1.3 9.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
1.3 7.8 GO:0097149 centralspindlin complex(GO:0097149)
1.2 1.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
1.2 8.6 GO:0097427 microtubule bundle(GO:0097427)
1.2 24.4 GO:0097225 sperm midpiece(GO:0097225)
1.1 171.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
1.0 4.8 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.8 11.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.7 17.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.7 69.2 GO:0036126 sperm flagellum(GO:0036126)
0.6 26.8 GO:0034451 centriolar satellite(GO:0034451)
0.6 9.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.6 11.6 GO:0036038 MKS complex(GO:0036038)
0.6 85.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.6 8.6 GO:0033010 paranodal junction(GO:0033010)
0.5 2.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.5 23.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.5 8.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.5 9.1 GO:0016342 catenin complex(GO:0016342)
0.5 42.2 GO:0005871 kinesin complex(GO:0005871)
0.5 6.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.5 9.5 GO:0008091 spectrin(GO:0008091)
0.4 1.3 GO:0097451 glial limiting end-foot(GO:0097451)
0.4 3.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.4 1.5 GO:0043291 RAVE complex(GO:0043291)
0.3 20.8 GO:0009925 basal plasma membrane(GO:0009925)
0.3 3.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 2.6 GO:0044294 dendritic growth cone(GO:0044294)
0.2 23.1 GO:0036064 ciliary basal body(GO:0036064)
0.2 9.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 6.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 4.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 23.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 105.1 GO:0005874 microtubule(GO:0005874)
0.2 2.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 3.5 GO:0032433 filopodium tip(GO:0032433)
0.2 17.7 GO:0042734 presynaptic membrane(GO:0042734)
0.2 13.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 7.9 GO:0043034 costamere(GO:0043034)
0.1 8.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 45.9 GO:0005929 cilium(GO:0005929)
0.1 10.4 GO:0043195 terminal bouton(GO:0043195)
0.1 0.9 GO:0070847 core mediator complex(GO:0070847)
0.1 3.7 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 12.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 6.3 GO:0016235 aggresome(GO:0016235)
0.1 1.0 GO:0000242 pericentriolar material(GO:0000242)
0.1 6.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 67.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 21.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 17.4 GO:0005819 spindle(GO:0005819)
0.1 4.1 GO:0030426 growth cone(GO:0030426)
0.1 9.7 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.0 GO:0001741 XY body(GO:0001741)
0.1 5.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 4.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 13.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.0 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 2.0 GO:0005814 centriole(GO:0005814)
0.0 4.2 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 5.6 GO:0043204 perikaryon(GO:0043204)
0.0 7.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 13.5 GO:0044297 cell body(GO:0044297)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 2.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 5.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.8 GO:1902911 protein kinase complex(GO:1902911)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 2.9 GO:0043005 neuron projection(GO:0043005)
0.0 0.5 GO:0005771 multivesicular body(GO:0005771)
0.0 4.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 11.4 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
3.0 11.9 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.8 11.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
2.6 31.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
2.5 7.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
2.2 13.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.7 12.1 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
1.7 12.0 GO:0004127 cytidylate kinase activity(GO:0004127)
1.6 4.7 GO:0031862 prostanoid receptor binding(GO:0031862)
1.5 35.4 GO:0045504 dynein heavy chain binding(GO:0045504)
1.5 11.9 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
1.4 17.2 GO:0071253 connexin binding(GO:0071253)
1.4 5.6 GO:0004802 transketolase activity(GO:0004802)
1.4 4.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
1.3 1.3 GO:0005119 smoothened binding(GO:0005119)
1.2 15.3 GO:0004565 beta-galactosidase activity(GO:0004565)
1.2 3.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
1.0 10.1 GO:0008158 hedgehog receptor activity(GO:0008158)
1.0 19.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.0 26.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.8 21.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.8 22.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.8 3.9 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.8 3.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.8 11.5 GO:0032027 myosin light chain binding(GO:0032027)
0.7 7.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.7 8.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.7 23.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.7 17.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.7 36.0 GO:0070840 dynein complex binding(GO:0070840)
0.7 52.8 GO:0003777 microtubule motor activity(GO:0003777)
0.7 2.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.7 20.4 GO:0030332 cyclin binding(GO:0030332)
0.6 3.7 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 7.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.6 9.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 12.6 GO:0004707 MAP kinase activity(GO:0004707)
0.5 9.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.5 13.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.5 5.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.5 1.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.5 4.6 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.4 13.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 3.9 GO:0004673 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673)
0.4 8.3 GO:0070513 death domain binding(GO:0070513)
0.4 8.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4 151.1 GO:0008017 microtubule binding(GO:0008017)
0.4 8.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 12.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.4 5.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.4 4.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 2.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.0 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 2.6 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 9.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.3 2.5 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.3 2.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 19.4 GO:0003785 actin monomer binding(GO:0003785)
0.3 9.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 2.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 21.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 2.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443)
0.3 6.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 9.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 3.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 7.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.4 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.2 1.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.2 12.8 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.2 1.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 6.5 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.2 10.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 11.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 6.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 26.3 GO:0008013 beta-catenin binding(GO:0008013)
0.2 4.0 GO:0044548 S100 protein binding(GO:0044548)
0.1 13.9 GO:0043022 ribosome binding(GO:0043022)
0.1 1.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 2.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 3.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 15.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 22.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 1.6 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 27.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 7.1 GO:0030552 cAMP binding(GO:0030552)
0.1 3.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 7.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 14.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 1.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 2.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 7.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 8.7 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.1 12.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 23.5 GO:0005516 calmodulin binding(GO:0005516)
0.1 64.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 33.3 GO:0003924 GTPase activity(GO:0003924)
0.1 2.1 GO:0005112 Notch binding(GO:0005112)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 2.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 1.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 3.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.2 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 1.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 18.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 8.0 GO:0005496 steroid binding(GO:0005496)
0.0 1.1 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 6.2 GO:0005178 integrin binding(GO:0005178)
0.0 1.7 GO:0001618 virus receptor activity(GO:0001618)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 4.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 3.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 2.7 GO:0002020 protease binding(GO:0002020)
0.0 11.5 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 5.4 GO:0016874 ligase activity(GO:0016874)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 16.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 15.3 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 28.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.6 44.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.4 20.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 11.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.2 11.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 16.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.1 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 8.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 10.2 PID AURORA B PATHWAY Aurora B signaling
0.1 11.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 8.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 3.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 7.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.1 PID AURORA A PATHWAY Aurora A signaling
0.1 5.7 PID NOTCH PATHWAY Notch signaling pathway
0.1 2.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 7.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 32.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9 26.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.9 40.9 REACTOME KINESINS Genes involved in Kinesins
0.6 11.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.6 18.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.5 21.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 2.8 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 14.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 18.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.3 5.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.2 6.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 4.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.2 13.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 9.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 28.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 25.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 6.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 8.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 6.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.6 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 4.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 28.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 3.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 3.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 12.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 3.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 5.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 7.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway