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Illumina Body Map 2: averaged replicates
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Results for RFX7_RFX4_RFX1
Z-value: 7.99
Motif logo
Transcription factors associated with RFX7_RFX4_RFX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RFX7
|
ENSG00000181827.10 | regulatory factor X7 |
|
RFX4
|
ENSG00000111783.8 | regulatory factor X4 |
|
RFX1
|
ENSG00000132005.4 | regulatory factor X1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RFX4 | hg19_v2_chr12_+_106994905_106994954 | 0.72 | 3.2e-06 | Click! |
| RFX1 | hg19_v2_chr19_-_14117074_14117141 | 0.32 | 7.6e-02 | Click! |
| RFX7 | hg19_v2_chr15_-_56535464_56535521 | 0.26 | 1.5e-01 | Click! |
Activity profile of RFX7_RFX4_RFX1 motif
Sorted Z-values of RFX7_RFX4_RFX1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_55888186 | 33.78 |
ENST00000291934.3
|
TMEM190
|
transmembrane protein 190 |
| chr1_-_109655377 | 31.80 |
ENST00000369948.3
|
C1orf194
|
chromosome 1 open reading frame 194 |
| chr1_-_109655355 | 30.33 |
ENST00000369945.3
|
C1orf194
|
chromosome 1 open reading frame 194 |
| chr10_+_23216944 | 27.70 |
ENST00000298032.5
ENST00000409983.3 ENST00000409049.3 |
ARMC3
|
armadillo repeat containing 3 |
| chr1_+_36549676 | 27.67 |
ENST00000207457.3
|
TEKT2
|
tektin 2 (testicular) |
| chr5_-_7851260 | 24.92 |
ENST00000509627.1
|
C5orf49
|
chromosome 5 open reading frame 49 |
| chr22_-_23484246 | 23.94 |
ENST00000216036.4
|
RTDR1
|
rhabdoid tumor deletion region gene 1 |
| chr2_+_54558004 | 23.55 |
ENST00000405749.1
ENST00000398634.2 ENST00000447328.1 |
C2orf73
|
chromosome 2 open reading frame 73 |
| chr2_-_170550877 | 23.23 |
ENST00000447353.1
|
CCDC173
|
coiled-coil domain containing 173 |
| chr10_+_23217006 | 22.76 |
ENST00000376528.4
ENST00000447081.1 |
ARMC3
|
armadillo repeat containing 3 |
| chr10_-_25305011 | 22.76 |
ENST00000331161.4
ENST00000376363.1 |
ENKUR
|
enkurin, TRPC channel interacting protein |
| chr16_+_80574854 | 22.04 |
ENST00000305904.6
ENST00000568035.1 |
DYNLRB2
|
dynein, light chain, roadblock-type 2 |
| chr2_-_170550842 | 21.03 |
ENST00000421028.1
|
CCDC173
|
coiled-coil domain containing 173 |
| chr8_-_67940755 | 20.85 |
ENST00000324682.5
|
PPP1R42
|
protein phosphatase 1, regulatory subunit 42 |
| chr2_-_196933536 | 20.45 |
ENST00000312428.6
ENST00000410072.1 |
DNAH7
|
dynein, axonemal, heavy chain 7 |
| chr1_-_205391178 | 18.95 |
ENST00000367153.4
ENST00000367151.2 ENST00000391936.2 ENST00000367149.3 |
LEMD1
|
LEM domain containing 1 |
| chr1_+_85527987 | 18.79 |
ENST00000326813.8
ENST00000294664.6 ENST00000528899.1 |
WDR63
|
WD repeat domain 63 |
| chr1_+_43613612 | 18.38 |
ENST00000335282.4
|
FAM183A
|
family with sequence similarity 183, member A |
| chr12_+_119772502 | 18.10 |
ENST00000536742.1
ENST00000327554.2 |
CCDC60
|
coiled-coil domain containing 60 |
| chr6_+_163148973 | 17.20 |
ENST00000366888.2
|
PACRG
|
PARK2 co-regulated |
| chr17_+_72270429 | 17.02 |
ENST00000311014.6
|
DNAI2
|
dynein, axonemal, intermediate chain 2 |
| chr10_+_15001430 | 16.98 |
ENST00000407572.1
|
MEIG1
|
meiosis/spermiogenesis associated 1 |
| chr17_+_45908974 | 16.78 |
ENST00000269025.4
|
LRRC46
|
leucine rich repeat containing 46 |
| chr20_+_56725952 | 16.22 |
ENST00000371168.3
|
C20orf85
|
chromosome 20 open reading frame 85 |
| chr5_-_137475071 | 15.90 |
ENST00000265191.2
|
NME5
|
NME/NM23 family member 5 |
| chr10_-_25304889 | 15.16 |
ENST00000483339.2
|
ENKUR
|
enkurin, TRPC channel interacting protein |
| chr17_+_72270380 | 14.98 |
ENST00000582036.1
ENST00000307504.5 |
DNAI2
|
dynein, axonemal, intermediate chain 2 |
| chr8_+_15397732 | 14.63 |
ENST00000382020.4
ENST00000506802.1 ENST00000509380.1 ENST00000503731.1 |
TUSC3
|
tumor suppressor candidate 3 |
| chr17_+_11501748 | 14.41 |
ENST00000262442.4
ENST00000579828.1 |
DNAH9
|
dynein, axonemal, heavy chain 9 |
| chr17_+_42977122 | 14.22 |
ENST00000412523.2
ENST00000331733.4 ENST00000417826.2 |
FAM187A
CCDC103
|
family with sequence similarity 187, member A coiled-coil domain containing 103 |
| chr17_+_42977062 | 14.09 |
ENST00000410006.2
ENST00000357776.2 ENST00000410027.1 |
CCDC103
|
coiled-coil domain containing 103 |
| chr9_-_138391692 | 14.00 |
ENST00000429260.2
|
C9orf116
|
chromosome 9 open reading frame 116 |
| chr1_-_169396666 | 13.59 |
ENST00000456107.1
ENST00000367805.3 |
CCDC181
|
coiled-coil domain containing 181 |
| chr9_+_130478345 | 13.47 |
ENST00000373289.3
ENST00000393748.4 |
TTC16
|
tetratricopeptide repeat domain 16 |
| chr2_+_26624775 | 12.92 |
ENST00000288710.2
|
DRC1
|
dynein regulatory complex subunit 1 homolog (Chlamydomonas) |
| chr11_+_61248583 | 12.92 |
ENST00000432063.2
ENST00000338608.2 |
PPP1R32
|
protein phosphatase 1, regulatory subunit 32 |
| chr1_-_169396646 | 12.91 |
ENST00000367806.3
|
CCDC181
|
coiled-coil domain containing 181 |
| chr19_+_2096868 | 12.82 |
ENST00000395296.1
ENST00000395301.3 |
IZUMO4
|
IZUMO family member 4 |
| chr8_-_101118185 | 12.42 |
ENST00000523437.1
|
RGS22
|
regulator of G-protein signaling 22 |
| chr1_+_43613566 | 12.35 |
ENST00000409396.1
|
FAM183A
|
family with sequence similarity 183, member A |
| chr21_-_43916296 | 12.29 |
ENST00000398352.3
|
RSPH1
|
radial spoke head 1 homolog (Chlamydomonas) |
| chr9_-_34381536 | 12.28 |
ENST00000379126.3
ENST00000379127.1 ENST00000379133.3 |
C9orf24
|
chromosome 9 open reading frame 24 |
| chrX_+_23925918 | 12.11 |
ENST00000379211.3
|
CXorf58
|
chromosome X open reading frame 58 |
| chr1_+_43637996 | 12.05 |
ENST00000528956.1
ENST00000529956.1 |
WDR65
|
WD repeat domain 65 |
| chr2_+_26785409 | 11.72 |
ENST00000329615.3
ENST00000409392.1 |
C2orf70
|
chromosome 2 open reading frame 70 |
| chr15_+_74610894 | 11.71 |
ENST00000558821.1
ENST00000268082.4 |
CCDC33
|
coiled-coil domain containing 33 |
| chr17_+_73642486 | 11.53 |
ENST00000579469.1
|
SMIM6
|
small integral membrane protein 6 |
| chr7_-_123174610 | 11.39 |
ENST00000324698.6
ENST00000434450.1 |
IQUB
|
IQ motif and ubiquitin domain containing |
| chr17_+_73642315 | 11.37 |
ENST00000556126.2
|
SMIM6
|
small integral membrane protein 6 |
| chr21_-_43916433 | 11.35 |
ENST00000291536.3
|
RSPH1
|
radial spoke head 1 homolog (Chlamydomonas) |
| chr1_-_118727781 | 11.29 |
ENST00000336338.5
|
SPAG17
|
sperm associated antigen 17 |
| chr10_+_118608998 | 10.92 |
ENST00000409522.1
ENST00000341276.5 ENST00000512864.2 |
ENO4
|
enolase family member 4 |
| chr19_-_46974741 | 10.69 |
ENST00000313683.10
ENST00000602246.1 |
PNMAL1
|
paraneoplastic Ma antigen family-like 1 |
| chr19_-_11545920 | 10.58 |
ENST00000356392.4
ENST00000591179.1 |
CCDC151
|
coiled-coil domain containing 151 |
| chr4_-_177116772 | 10.52 |
ENST00000280191.2
|
SPATA4
|
spermatogenesis associated 4 |
| chrX_+_133371077 | 10.51 |
ENST00000517294.1
ENST00000370809.4 |
CCDC160
|
coiled-coil domain containing 160 |
| chr12_-_113658892 | 10.27 |
ENST00000299732.2
ENST00000416617.2 |
IQCD
|
IQ motif containing D |
| chr17_+_17876127 | 10.26 |
ENST00000582416.1
ENST00000313838.8 ENST00000411504.2 ENST00000581264.1 ENST00000399187.1 ENST00000479684.2 ENST00000584166.1 ENST00000585108.1 ENST00000399182.1 ENST00000579977.1 |
LRRC48
|
leucine rich repeat containing 48 |
| chr17_+_11501816 | 10.25 |
ENST00000454412.2
|
DNAH9
|
dynein, axonemal, heavy chain 9 |
| chr9_-_34381511 | 10.22 |
ENST00000379124.1
|
C9orf24
|
chromosome 9 open reading frame 24 |
| chr12_+_122667658 | 10.20 |
ENST00000339777.4
ENST00000425921.1 |
LRRC43
|
leucine rich repeat containing 43 |
| chr9_+_34458771 | 10.10 |
ENST00000437363.1
ENST00000242317.4 |
DNAI1
|
dynein, axonemal, intermediate chain 1 |
| chr8_-_101117847 | 9.81 |
ENST00000523287.1
ENST00000519092.1 |
RGS22
|
regulator of G-protein signaling 22 |
| chr19_-_46974664 | 9.73 |
ENST00000438932.2
|
PNMAL1
|
paraneoplastic Ma antigen family-like 1 |
| chr3_-_10149907 | 9.67 |
ENST00000450660.2
ENST00000524279.1 |
FANCD2OS
|
FANCD2 opposite strand |
| chr4_+_146601356 | 9.60 |
ENST00000438731.1
ENST00000511965.1 |
C4orf51
|
chromosome 4 open reading frame 51 |
| chr17_-_15244894 | 9.57 |
ENST00000338696.2
ENST00000543896.1 ENST00000539245.1 ENST00000539316.1 ENST00000395930.1 |
TEKT3
|
tektin 3 |
| chr5_-_121659052 | 9.57 |
ENST00000512105.1
|
CTD-2544H17.1
|
CTD-2544H17.1 |
| chr4_-_56458374 | 9.34 |
ENST00000295645.4
|
PDCL2
|
phosducin-like 2 |
| chr1_-_45308616 | 9.14 |
ENST00000447098.2
ENST00000372192.3 |
PTCH2
|
patched 2 |
| chr17_+_48585745 | 9.11 |
ENST00000323776.5
|
MYCBPAP
|
MYCBP associated protein |
| chr8_+_144798429 | 8.88 |
ENST00000338033.4
ENST00000395107.4 ENST00000395108.2 |
MAPK15
|
mitogen-activated protein kinase 15 |
| chr12_-_113658826 | 8.82 |
ENST00000546692.1
|
IQCD
|
IQ motif containing D |
| chr10_-_82116467 | 8.75 |
ENST00000454362.1
|
DYDC1
|
DPY30 domain containing 1 |
| chr12_+_96883347 | 8.74 |
ENST00000524981.4
ENST00000298953.3 |
C12orf55
|
chromosome 12 open reading frame 55 |
| chr17_-_8648105 | 8.64 |
ENST00000539522.2
ENST00000293845.3 |
CCDC42
|
coiled-coil domain containing 42 |
| chr12_+_119772734 | 8.51 |
ENST00000539847.1
|
CCDC60
|
coiled-coil domain containing 60 |
| chr1_-_60539422 | 8.47 |
ENST00000371201.3
|
C1orf87
|
chromosome 1 open reading frame 87 |
| chr3_-_167098059 | 8.41 |
ENST00000392764.1
ENST00000474464.1 ENST00000392766.2 ENST00000485651.1 |
ZBBX
|
zinc finger, B-box domain containing |
| chr8_-_101118210 | 8.41 |
ENST00000360863.6
|
RGS22
|
regulator of G-protein signaling 22 |
| chr1_-_60539405 | 8.36 |
ENST00000450089.2
|
C1orf87
|
chromosome 1 open reading frame 87 |
| chr6_+_116937636 | 8.31 |
ENST00000368581.4
ENST00000229554.5 ENST00000368580.4 |
RSPH4A
|
radial spoke head 4 homolog A (Chlamydomonas) |
| chr8_+_10530133 | 8.29 |
ENST00000304519.5
|
C8orf74
|
chromosome 8 open reading frame 74 |
| chr2_+_84743562 | 8.21 |
ENST00000389394.3
ENST00000398278.2 |
DNAH6
|
dynein, axonemal, heavy chain 6 |
| chr22_+_45809560 | 8.18 |
ENST00000342894.3
ENST00000538017.1 |
RIBC2
|
RIB43A domain with coiled-coils 2 |
| chr1_-_75139397 | 8.17 |
ENST00000326665.5
|
C1orf173
|
chromosome 1 open reading frame 173 |
| chr1_+_161068179 | 8.00 |
ENST00000368011.4
ENST00000392192.2 |
KLHDC9
|
kelch domain containing 9 |
| chr10_-_82116505 | 7.96 |
ENST00000372202.1
ENST00000421924.2 ENST00000453477.1 |
DYDC1
|
DPY30 domain containing 1 |
| chr16_-_85146040 | 7.75 |
ENST00000539556.1
|
FAM92B
|
family with sequence similarity 92, member B |
| chr1_-_1935153 | 7.66 |
ENST00000434971.2
|
C1orf222
|
chromosome 1 open reading frame 222 |
| chr15_+_67547113 | 7.56 |
ENST00000512104.1
ENST00000358767.3 ENST00000546225.1 |
IQCH
|
IQ motif containing H |
| chr1_+_115642293 | 7.42 |
ENST00000448680.1
|
RP4-666F24.3
|
RP4-666F24.3 |
| chr5_-_110074603 | 7.41 |
ENST00000515278.2
|
TMEM232
|
transmembrane protein 232 |
| chr15_-_55790515 | 7.41 |
ENST00000448430.2
ENST00000457155.2 |
DYX1C1
|
dyslexia susceptibility 1 candidate 1 |
| chr17_+_48585902 | 7.33 |
ENST00000452039.1
|
MYCBPAP
|
MYCBP associated protein |
| chr8_-_11324273 | 7.28 |
ENST00000284486.4
|
FAM167A
|
family with sequence similarity 167, member A |
| chr11_+_86085778 | 7.08 |
ENST00000354755.1
ENST00000278487.3 ENST00000531271.1 ENST00000445632.2 |
CCDC81
|
coiled-coil domain containing 81 |
| chr11_-_85397167 | 7.06 |
ENST00000316398.3
|
CCDC89
|
coiled-coil domain containing 89 |
| chr13_-_103046837 | 6.98 |
ENST00000607251.1
|
FGF14-IT1
|
FGF14 intronic transcript 1 (non-protein coding) |
| chr17_+_48585958 | 6.93 |
ENST00000436259.2
|
MYCBPAP
|
MYCBP associated protein |
| chr6_-_165723088 | 6.91 |
ENST00000230301.8
|
C6orf118
|
chromosome 6 open reading frame 118 |
| chr14_+_96858433 | 6.87 |
ENST00000267584.4
|
AK7
|
adenylate kinase 7 |
| chr4_+_176987131 | 6.79 |
ENST00000280190.4
|
WDR17
|
WD repeat domain 17 |
| chr6_-_24799117 | 6.75 |
ENST00000565469.1
|
RP3-369A17.5
|
chromosome 6 open reading frame 229 |
| chr11_+_71791803 | 6.70 |
ENST00000539271.1
|
LRTOMT
|
leucine rich transmembrane and O-methyltransferase domain containing |
| chr17_-_60885700 | 6.64 |
ENST00000583600.1
|
MARCH10
|
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase |
| chr17_-_60885645 | 6.61 |
ENST00000544856.2
|
MARCH10
|
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase |
| chr5_-_110062349 | 6.60 |
ENST00000511883.2
ENST00000455884.2 |
TMEM232
|
transmembrane protein 232 |
| chr9_+_34458851 | 6.55 |
ENST00000545019.1
|
DNAI1
|
dynein, axonemal, intermediate chain 1 |
| chr1_+_64669294 | 6.53 |
ENST00000371077.5
|
UBE2U
|
ubiquitin-conjugating enzyme E2U (putative) |
| chr9_+_72435709 | 6.44 |
ENST00000377197.3
ENST00000527647.1 |
C9orf135
|
chromosome 9 open reading frame 135 |
| chr11_+_6260298 | 6.42 |
ENST00000379936.2
|
CNGA4
|
cyclic nucleotide gated channel alpha 4 |
| chr15_+_67547163 | 6.38 |
ENST00000335894.4
|
IQCH
|
IQ motif containing H |
| chr17_-_60885659 | 6.34 |
ENST00000311269.5
|
MARCH10
|
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase |
| chr10_+_82116529 | 6.33 |
ENST00000411538.1
ENST00000256039.2 |
DYDC2
|
DPY30 domain containing 2 |
| chr22_-_45809495 | 6.29 |
ENST00000404354.3
|
SMC1B
|
structural maintenance of chromosomes 1B |
| chr19_+_55996543 | 6.25 |
ENST00000591590.1
|
NAT14
|
N-acetyltransferase 14 (GCN5-related, putative) |
| chr1_+_206809113 | 6.23 |
ENST00000441486.1
ENST00000367106.1 |
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| chrX_-_114252193 | 6.23 |
ENST00000243213.1
|
IL13RA2
|
interleukin 13 receptor, alpha 2 |
| chr9_+_130469257 | 6.22 |
ENST00000373295.2
|
C9orf117
|
chromosome 9 open reading frame 117 |
| chr1_-_85156417 | 6.08 |
ENST00000422026.1
|
SSX2IP
|
synovial sarcoma, X breakpoint 2 interacting protein |
| chr3_-_19975665 | 6.07 |
ENST00000295824.9
ENST00000389256.4 |
EFHB
|
EF-hand domain family, member B |
| chr7_-_105221898 | 5.95 |
ENST00000486180.1
ENST00000485614.1 ENST00000480514.1 |
EFCAB10
|
EF-hand calcium binding domain 10 |
| chr1_+_1981890 | 5.94 |
ENST00000378567.3
ENST00000468310.1 |
PRKCZ
|
protein kinase C, zeta |
| chr10_+_106113515 | 5.89 |
ENST00000369704.3
ENST00000312902.5 |
CCDC147
|
coiled-coil domain containing 147 |
| chr6_+_147091575 | 5.87 |
ENST00000326916.8
ENST00000470716.2 ENST00000367488.1 |
ADGB
|
androglobin |
| chr18_-_47792851 | 5.83 |
ENST00000398545.4
|
CCDC11
|
coiled-coil domain containing 11 |
| chr11_-_8954491 | 5.75 |
ENST00000526227.1
ENST00000525780.1 ENST00000326053.5 |
C11orf16
|
chromosome 11 open reading frame 16 |
| chr6_+_146920097 | 5.73 |
ENST00000397944.3
ENST00000522242.1 |
ADGB
|
androglobin |
| chr20_+_30467600 | 5.61 |
ENST00000375934.4
ENST00000375922.4 |
TTLL9
|
tubulin tyrosine ligase-like family, member 9 |
| chr4_+_81256871 | 5.60 |
ENST00000358105.3
ENST00000508675.1 |
C4orf22
|
chromosome 4 open reading frame 22 |
| chr8_+_94767109 | 5.59 |
ENST00000409623.3
ENST00000453906.1 ENST00000521517.1 |
TMEM67
|
transmembrane protein 67 |
| chr4_-_156297949 | 5.58 |
ENST00000515654.1
|
MAP9
|
microtubule-associated protein 9 |
| chr9_-_117267717 | 5.57 |
ENST00000374057.3
|
DFNB31
|
deafness, autosomal recessive 31 |
| chr3_-_48659193 | 5.52 |
ENST00000330862.3
|
TMEM89
|
transmembrane protein 89 |
| chr20_-_44420507 | 5.52 |
ENST00000243938.4
|
WFDC3
|
WAP four-disulfide core domain 3 |
| chr5_-_110062384 | 5.48 |
ENST00000429839.2
|
TMEM232
|
transmembrane protein 232 |
| chr3_+_63638339 | 5.43 |
ENST00000343837.3
ENST00000469440.1 |
SNTN
|
sentan, cilia apical structure protein |
| chr15_+_40531621 | 5.42 |
ENST00000560346.1
|
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr1_+_111889212 | 5.41 |
ENST00000369737.4
|
PIFO
|
primary cilia formation |
| chr15_+_40531243 | 5.41 |
ENST00000558055.1
ENST00000455577.2 |
PAK6
|
p21 protein (Cdc42/Rac)-activated kinase 6 |
| chr12_+_49297899 | 5.41 |
ENST00000552942.1
ENST00000320516.4 |
CCDC65
|
coiled-coil domain containing 65 |
| chr4_+_2420659 | 5.39 |
ENST00000382849.2
|
RP11-503N18.1
|
RP11-503N18.1 |
| chr5_+_132149017 | 5.35 |
ENST00000378693.2
|
SOWAHA
|
sosondowah ankyrin repeat domain family member A |
| chr14_+_105452094 | 5.33 |
ENST00000551606.1
ENST00000547315.1 |
C14orf79
|
chromosome 14 open reading frame 79 |
| chr4_+_176986978 | 5.31 |
ENST00000508596.1
ENST00000393643.2 |
WDR17
|
WD repeat domain 17 |
| chr17_+_42733730 | 5.28 |
ENST00000359945.3
ENST00000425535.1 |
C17orf104
|
chromosome 17 open reading frame 104 |
| chr1_-_36916011 | 5.28 |
ENST00000356637.5
ENST00000354267.3 ENST00000235532.5 |
OSCP1
|
organic solute carrier partner 1 |
| chr12_+_85430110 | 5.15 |
ENST00000393212.3
ENST00000393217.2 |
LRRIQ1
|
leucine-rich repeats and IQ motif containing 1 |
| chrX_+_35937843 | 5.15 |
ENST00000297866.5
|
CXorf22
|
chromosome X open reading frame 22 |
| chr12_-_100660833 | 5.12 |
ENST00000551642.1
ENST00000416321.1 ENST00000550587.1 ENST00000549249.1 |
DEPDC4
|
DEP domain containing 4 |
| chr10_-_28287968 | 5.10 |
ENST00000305242.5
|
ARMC4
|
armadillo repeat containing 4 |
| chr8_+_94767072 | 5.09 |
ENST00000452276.1
ENST00000453321.3 ENST00000498673.1 ENST00000518319.1 |
TMEM67
|
transmembrane protein 67 |
| chr16_-_30064244 | 5.09 |
ENST00000571269.1
ENST00000561666.1 |
FAM57B
|
family with sequence similarity 57, member B |
| chr19_+_751122 | 5.08 |
ENST00000215582.6
|
MISP
|
mitotic spindle positioning |
| chr1_-_40157345 | 5.05 |
ENST00000372844.3
|
HPCAL4
|
hippocalcin like 4 |
| chr1_-_21044489 | 5.02 |
ENST00000247986.2
|
KIF17
|
kinesin family member 17 |
| chr5_+_127039075 | 5.01 |
ENST00000514853.2
|
CTC-228N24.1
|
CTC-228N24.1 |
| chr16_-_30773372 | 4.99 |
ENST00000545825.1
ENST00000541260.1 |
C16orf93
|
chromosome 16 open reading frame 93 |
| chr11_-_47736896 | 4.94 |
ENST00000525123.1
ENST00000528244.1 ENST00000532595.1 ENST00000529154.1 ENST00000530969.1 |
AGBL2
|
ATP/GTP binding protein-like 2 |
| chr11_+_124543694 | 4.93 |
ENST00000227135.2
ENST00000532692.1 |
SPA17
|
sperm autoantigenic protein 17 |
| chrX_-_44202857 | 4.93 |
ENST00000420999.1
|
EFHC2
|
EF-hand domain (C-terminal) containing 2 |
| chr17_+_54230819 | 4.86 |
ENST00000318698.2
ENST00000566473.2 |
ANKFN1
|
ankyrin-repeat and fibronectin type III domain containing 1 |
| chr1_+_111888890 | 4.85 |
ENST00000369738.4
|
PIFO
|
primary cilia formation |
| chr7_-_36406750 | 4.84 |
ENST00000453212.1
ENST00000415803.2 ENST00000440378.1 ENST00000431396.1 ENST00000317020.6 ENST00000436884.1 |
KIAA0895
|
KIAA0895 |
| chr1_+_20512568 | 4.83 |
ENST00000375099.3
|
UBXN10
|
UBX domain protein 10 |
| chr1_-_36915880 | 4.81 |
ENST00000445843.3
|
OSCP1
|
organic solute carrier partner 1 |
| chr10_-_82116497 | 4.79 |
ENST00000372204.3
|
DYDC1
|
DPY30 domain containing 1 |
| chr9_+_72435749 | 4.76 |
ENST00000480564.1
|
C9orf135
|
chromosome 9 open reading frame 135 |
| chr11_-_8615488 | 4.76 |
ENST00000315204.1
ENST00000396672.1 ENST00000396673.1 |
STK33
|
serine/threonine kinase 33 |
| chr2_+_202937972 | 4.69 |
ENST00000541917.1
ENST00000295844.3 |
AC079354.1
|
uncharacterized protein KIAA2012 |
| chr1_-_36916066 | 4.68 |
ENST00000315643.9
|
OSCP1
|
organic solute carrier partner 1 |
| chr1_+_32674675 | 4.64 |
ENST00000409358.1
|
DCDC2B
|
doublecortin domain containing 2B |
| chr10_-_134756030 | 4.61 |
ENST00000368586.5
ENST00000368582.2 |
TTC40
|
tetratricopeptide repeat domain 40 |
| chr19_+_55996316 | 4.57 |
ENST00000205194.4
|
NAT14
|
N-acetyltransferase 14 (GCN5-related, putative) |
| chr6_+_146920116 | 4.56 |
ENST00000367493.3
|
ADGB
|
androglobin |
| chr11_-_8615687 | 4.53 |
ENST00000534493.1
ENST00000422559.2 |
STK33
|
serine/threonine kinase 33 |
| chr3_+_39149145 | 4.52 |
ENST00000301819.6
ENST00000431162.2 |
TTC21A
|
tetratricopeptide repeat domain 21A |
| chr5_-_54529415 | 4.52 |
ENST00000282572.4
|
CCNO
|
cyclin O |
| chr7_+_12544025 | 4.49 |
ENST00000443874.1
ENST00000424453.1 |
AC005281.1
|
AC005281.1 |
| chr6_-_49755019 | 4.48 |
ENST00000304801.3
|
PGK2
|
phosphoglycerate kinase 2 |
| chr2_-_207630033 | 4.41 |
ENST00000449792.1
|
MDH1B
|
malate dehydrogenase 1B, NAD (soluble) |
| chr1_+_206808868 | 4.41 |
ENST00000367109.2
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| chr2_-_207629997 | 4.38 |
ENST00000454776.2
|
MDH1B
|
malate dehydrogenase 1B, NAD (soluble) |
| chr8_-_101118439 | 4.36 |
ENST00000519408.1
|
RGS22
|
regulator of G-protein signaling 22 |
| chr21_+_18885318 | 4.35 |
ENST00000400166.1
|
CXADR
|
coxsackie virus and adenovirus receptor |
| chr3_+_39149298 | 4.33 |
ENST00000440121.1
|
TTC21A
|
tetratricopeptide repeat domain 21A |
| chr4_-_153700864 | 4.32 |
ENST00000304337.2
|
TIGD4
|
tigger transposable element derived 4 |
| chr1_+_206808918 | 4.32 |
ENST00000367108.3
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| chr1_+_1109272 | 4.30 |
ENST00000379290.1
ENST00000379289.1 |
TTLL10
|
tubulin tyrosine ligase-like family, member 10 |
| chr2_-_220110187 | 4.28 |
ENST00000295759.7
ENST00000392089.2 |
GLB1L
|
galactosidase, beta 1-like |
| chr4_+_100432161 | 4.26 |
ENST00000326581.4
ENST00000514652.1 |
C4orf17
|
chromosome 4 open reading frame 17 |
| chr1_-_74663825 | 4.21 |
ENST00000370911.3
ENST00000370909.2 ENST00000354431.4 |
LRRIQ3
|
leucine-rich repeats and IQ motif containing 3 |
| chr12_+_13061894 | 4.20 |
ENST00000540125.1
|
GPRC5A
|
G protein-coupled receptor, family C, group 5, member A |
| chr11_-_8615720 | 4.18 |
ENST00000358872.3
ENST00000454443.2 |
STK33
|
serine/threonine kinase 33 |
| chr5_+_121465234 | 4.09 |
ENST00000504912.1
ENST00000505843.1 |
ZNF474
|
zinc finger protein 474 |
| chr14_+_75536280 | 4.00 |
ENST00000238686.8
|
ZC2HC1C
|
zinc finger, C2HC-type containing 1C |
| chr6_-_43478239 | 4.00 |
ENST00000372441.1
|
LRRC73
|
leucine rich repeat containing 73 |
| chr5_+_121465207 | 3.95 |
ENST00000296600.4
|
ZNF474
|
zinc finger protein 474 |
| chrX_-_115828156 | 3.93 |
ENST00000446495.1
|
RP11-232D9.3
|
RP11-232D9.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RFX7_RFX4_RFX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 67.4 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 4.2 | 76.4 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 4.1 | 8.2 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) |
| 3.1 | 6.2 | GO:1904031 | positive regulation of cyclin-dependent protein kinase activity(GO:1904031) |
| 3.0 | 15.0 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 2.8 | 14.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 2.1 | 6.3 | GO:1903251 | multi-ciliated epithelial cell differentiation(GO:1903251) |
| 1.9 | 9.6 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 1.9 | 5.7 | GO:1903452 | regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452) |
| 1.9 | 9.3 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 1.9 | 16.7 | GO:0070286 | axonemal dynein complex assembly(GO:0070286) |
| 1.8 | 34.4 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 1.6 | 38.3 | GO:0003341 | cilium movement(GO:0003341) |
| 1.4 | 23.6 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 1.3 | 7.8 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
| 1.3 | 5.0 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 1.2 | 14.9 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 1.2 | 3.7 | GO:0044727 | DNA demethylation of male pronucleus(GO:0044727) |
| 1.1 | 21.7 | GO:0035082 | axoneme assembly(GO:0035082) |
| 1.1 | 3.2 | GO:0051040 | regulation of calcium-independent cell-cell adhesion(GO:0051040) |
| 1.0 | 3.0 | GO:1903964 | monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966) |
| 1.0 | 3.0 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 1.0 | 72.0 | GO:0042073 | intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840) |
| 1.0 | 7.8 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
| 0.9 | 14.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.7 | 4.3 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.7 | 3.5 | GO:0070829 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.7 | 2.0 | GO:0016999 | antibiotic metabolic process(GO:0016999) |
| 0.7 | 9.1 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.6 | 5.6 | GO:0002318 | myeloid progenitor cell differentiation(GO:0002318) |
| 0.6 | 12.2 | GO:0042424 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.6 | 2.3 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.6 | 1.7 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397) |
| 0.5 | 2.2 | GO:0090299 | regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.5 | 10.7 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.5 | 3.6 | GO:0048165 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) |
| 0.5 | 8.8 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.5 | 2.6 | GO:1904491 | protein localization to ciliary transition zone(GO:1904491) |
| 0.5 | 5.5 | GO:1903546 | protein localization to photoreceptor outer segment(GO:1903546) |
| 0.5 | 5.9 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 0.5 | 2.5 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.5 | 6.5 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.5 | 3.6 | GO:0007341 | penetration of zona pellucida(GO:0007341) |
| 0.4 | 5.9 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.4 | 2.5 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
| 0.4 | 2.9 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
| 0.4 | 1.1 | GO:0060304 | regulation of phosphatidylinositol dephosphorylation(GO:0060304) |
| 0.4 | 1.8 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.3 | 6.2 | GO:0002638 | negative regulation of immunoglobulin production(GO:0002638) |
| 0.3 | 6.9 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.3 | 0.9 | GO:1902871 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871) |
| 0.3 | 1.2 | GO:1905154 | negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.3 | 8.6 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.3 | 1.2 | GO:1900533 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
| 0.3 | 2.6 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.3 | 0.9 | GO:0006173 | dADP biosynthetic process(GO:0006173) |
| 0.3 | 1.4 | GO:2000638 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.3 | 0.8 | GO:0097106 | postsynaptic density organization(GO:0097106) |
| 0.3 | 0.5 | GO:0061053 | somite development(GO:0061053) |
| 0.3 | 1.4 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.3 | 2.4 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
| 0.3 | 1.6 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
| 0.3 | 1.3 | GO:1903751 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
| 0.3 | 1.1 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.3 | 0.8 | GO:0001694 | histamine biosynthetic process(GO:0001694) |
| 0.3 | 0.8 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.2 | 1.9 | GO:2000825 | positive regulation of androgen receptor activity(GO:2000825) |
| 0.2 | 0.7 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.2 | 32.4 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.2 | 2.2 | GO:0060075 | regulation of resting membrane potential(GO:0060075) |
| 0.2 | 2.0 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.2 | 1.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.2 | 3.8 | GO:0030317 | sperm motility(GO:0030317) |
| 0.2 | 8.7 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.2 | 0.2 | GO:0034125 | negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) |
| 0.2 | 0.9 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.2 | 1.5 | GO:1900180 | regulation of protein localization to nucleus(GO:1900180) |
| 0.2 | 2.0 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.2 | 1.4 | GO:1903244 | positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) |
| 0.2 | 30.2 | GO:0007286 | spermatid development(GO:0007286) |
| 0.2 | 1.9 | GO:0090043 | regulation of tubulin deacetylation(GO:0090043) |
| 0.2 | 1.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.2 | 1.4 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.2 | 10.8 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.2 | 1.0 | GO:0050893 | sensory processing(GO:0050893) |
| 0.2 | 3.2 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.2 | 5.5 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.2 | 5.5 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 0.4 | GO:0016237 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) |
| 0.1 | 2.3 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.1 | 2.3 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
| 0.1 | 2.8 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.1 | 0.7 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 2.1 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 4.4 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.1 | 1.2 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
| 0.1 | 0.5 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.1 | 0.4 | GO:0021997 | neural plate axis specification(GO:0021997) |
| 0.1 | 1.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.1 | 0.4 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.1 | 1.7 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.1 | 1.1 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.1 | 1.6 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 1.1 | GO:0010792 | DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) |
| 0.1 | 0.4 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 0.7 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 2.0 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.1 | 1.7 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 1.0 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 0.8 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 0.9 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.1 | 1.5 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
| 0.1 | 0.3 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 0.1 | 0.3 | GO:0060298 | positive regulation of sarcomere organization(GO:0060298) |
| 0.1 | 1.0 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 0.1 | 1.2 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 3.5 | GO:0042407 | cristae formation(GO:0042407) |
| 0.1 | 0.3 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
| 0.1 | 14.4 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
| 0.1 | 0.3 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.1 | 0.2 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.1 | 0.3 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.1 | 0.5 | GO:0072092 | ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.1 | 0.9 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.1 | 3.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 2.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.1 | 1.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 0.7 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 1.5 | GO:0007220 | Notch receptor processing(GO:0007220) |
| 0.1 | 0.6 | GO:0010727 | negative regulation of hydrogen peroxide metabolic process(GO:0010727) |
| 0.1 | 1.1 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 0.1 | 3.6 | GO:0006739 | NADP metabolic process(GO:0006739) |
| 0.1 | 9.9 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.1 | 1.0 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.1 | 0.9 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.1 | 0.1 | GO:2000582 | regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.1 | 0.8 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 1.4 | GO:0021542 | dentate gyrus development(GO:0021542) |
| 0.1 | 0.6 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.0 | 3.6 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 2.5 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.1 | GO:0010983 | positive regulation of high-density lipoprotein particle clearance(GO:0010983) |
| 0.0 | 3.6 | GO:0021795 | cerebral cortex cell migration(GO:0021795) |
| 0.0 | 1.6 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 19.2 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.0 | 0.8 | GO:0034976 | response to endoplasmic reticulum stress(GO:0034976) |
| 0.0 | 2.0 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.5 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.0 | 3.1 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 1.3 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.0 | 3.5 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.0 | 10.1 | GO:0007018 | microtubule-based movement(GO:0007018) |
| 0.0 | 0.5 | GO:0019374 | galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) |
| 0.0 | 1.7 | GO:0008045 | motor neuron axon guidance(GO:0008045) |
| 0.0 | 1.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.3 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.0 | 0.3 | GO:0050686 | negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 1.6 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 9.9 | GO:0060271 | cilium morphogenesis(GO:0060271) |
| 0.0 | 2.0 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 1.6 | GO:0006294 | nucleotide-excision repair, preincision complex assembly(GO:0006294) |
| 0.0 | 2.6 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 10.8 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 1.6 | GO:0045124 | regulation of bone resorption(GO:0045124) |
| 0.0 | 1.6 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 18.9 | GO:0007283 | spermatogenesis(GO:0007283) |
| 0.0 | 0.6 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
| 0.0 | 0.4 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.0 | 0.2 | GO:0009099 | branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099) |
| 0.0 | 0.2 | GO:0007369 | gastrulation(GO:0007369) |
| 0.0 | 0.3 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.0 | 1.2 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 1.1 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.0 | 0.1 | GO:0097359 | UDP-glucosylation(GO:0097359) |
| 0.0 | 5.8 | GO:0021915 | neural tube development(GO:0021915) |
| 0.0 | 0.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.4 | GO:0007099 | centriole replication(GO:0007099) |
| 0.0 | 0.4 | GO:0043392 | negative regulation of DNA binding(GO:0043392) |
| 0.0 | 0.5 | GO:0061001 | regulation of dendritic spine morphogenesis(GO:0061001) |
| 0.0 | 3.7 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.2 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
| 0.0 | 0.6 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.3 | GO:0010165 | response to X-ray(GO:0010165) |
| 0.0 | 0.4 | GO:0048511 | rhythmic process(GO:0048511) |
| 0.0 | 0.1 | GO:0006601 | creatine biosynthetic process(GO:0006601) |
| 0.0 | 0.1 | GO:2001178 | mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178) |
| 0.0 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 1.9 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.0 | 1.8 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 2.0 | GO:1990830 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.0 | 1.2 | GO:0014047 | glutamate secretion(GO:0014047) |
| 0.0 | 0.3 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.0 | 1.3 | GO:0001942 | hair follicle development(GO:0001942) |
| 0.0 | 1.8 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.1 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.0 | 0.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 3.2 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.0 | 0.1 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.4 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 1.9 | GO:0006338 | chromatin remodeling(GO:0006338) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.8 | 33.8 | GO:0002079 | inner acrosomal membrane(GO:0002079) |
| 6.1 | 48.8 | GO:0002177 | manchette(GO:0002177) |
| 5.7 | 73.8 | GO:0036157 | outer dynein arm(GO:0036157) |
| 4.9 | 14.6 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 3.3 | 16.7 | GO:0036156 | inner dynein arm(GO:0036156) |
| 2.8 | 8.3 | GO:0001534 | radial spoke(GO:0001534) |
| 2.1 | 8.2 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 1.8 | 5.5 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 1.7 | 23.9 | GO:0072687 | meiotic spindle(GO:0072687) |
| 1.7 | 10.1 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 1.2 | 3.7 | GO:0042585 | germinal vesicle(GO:0042585) |
| 1.2 | 10.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 1.2 | 4.8 | GO:0016939 | kinesin II complex(GO:0016939) |
| 1.1 | 4.5 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 1.0 | 28.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 1.0 | 43.9 | GO:0097228 | sperm principal piece(GO:0097228) |
| 1.0 | 17.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.9 | 140.1 | GO:0031514 | motile cilium(GO:0031514) |
| 0.9 | 14.5 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.7 | 8.9 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.7 | 13.4 | GO:0030990 | intraciliary transport particle(GO:0030990) |
| 0.7 | 2.8 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.7 | 14.5 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.7 | 3.4 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.6 | 12.8 | GO:0036038 | MKS complex(GO:0036038) |
| 0.5 | 52.9 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.4 | 2.2 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.4 | 3.5 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.4 | 6.2 | GO:0005883 | neurofilament(GO:0005883) |
| 0.4 | 6.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.3 | 4.8 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.3 | 5.9 | GO:0045179 | apical cortex(GO:0045179) |
| 0.3 | 1.0 | GO:0031021 | interphase microtubule organizing center(GO:0031021) |
| 0.3 | 11.7 | GO:0097546 | ciliary base(GO:0097546) |
| 0.3 | 14.3 | GO:0030286 | dynein complex(GO:0030286) |
| 0.3 | 1.2 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.3 | 2.0 | GO:0098536 | deuterosome(GO:0098536) |
| 0.2 | 14.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.2 | 16.3 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.2 | 9.1 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 1.5 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.2 | 7.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 1.2 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.2 | 1.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.2 | 1.4 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.2 | 2.1 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.2 | 5.7 | GO:0071565 | nBAF complex(GO:0071565) |
| 0.2 | 3.8 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.2 | 0.7 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.2 | 14.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 12.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 1.7 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 35.9 | GO:0005929 | cilium(GO:0005929) |
| 0.1 | 2.0 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 2.6 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 0.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 4.2 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.7 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 0.9 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 5.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 3.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 0.6 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.1 | 1.0 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 3.3 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 3.0 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 11.0 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 7.1 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.5 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 1.3 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
| 0.0 | 0.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 1.5 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 5.2 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 4.2 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 0.6 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.5 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 1.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.3 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.0 | 1.8 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.9 | GO:0098858 | actin-based cell projection(GO:0098858) |
| 0.0 | 1.1 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.0 | 2.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 1.0 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.9 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.2 | GO:0002199 | zona pellucida receptor complex(GO:0002199) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 74.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 2.2 | 71.7 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 2.1 | 6.2 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
| 2.0 | 6.1 | GO:0052856 | NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857) |
| 2.0 | 6.1 | GO:0015633 | zinc transporting ATPase activity(GO:0015633) |
| 1.5 | 4.5 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
| 1.5 | 10.4 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 1.4 | 8.6 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 1.4 | 12.2 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 1.3 | 9.1 | GO:0005119 | smoothened binding(GO:0005119) |
| 1.2 | 10.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 1.0 | 8.8 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
| 0.9 | 28.3 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.9 | 5.5 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.9 | 14.5 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.7 | 6.2 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.7 | 3.5 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.7 | 2.0 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.7 | 7.8 | GO:0071253 | connexin binding(GO:0071253) |
| 0.6 | 17.2 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.6 | 12.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.6 | 7.5 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.6 | 4.5 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 0.5 | 1.6 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.5 | 3.7 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.4 | 31.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.4 | 1.7 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 0.4 | 4.3 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.4 | 15.2 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.3 | 32.3 | GO:0043621 | protein self-association(GO:0043621) |
| 0.3 | 10.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.3 | 3.0 | GO:0016215 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.3 | 15.1 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.3 | 3.6 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.3 | 5.1 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.3 | 1.2 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.3 | 1.1 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
| 0.3 | 1.6 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.3 | 8.9 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.2 | 5.7 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.2 | 5.9 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.2 | 2.3 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.2 | 2.5 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.2 | 7.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.2 | 7.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.2 | 7.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.2 | 1.1 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.2 | 5.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.2 | 1.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 13.3 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.2 | 2.0 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.2 | 3.3 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.2 | 4.3 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.2 | 11.0 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.2 | 5.2 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 0.4 | GO:0019778 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
| 0.1 | 10.4 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 1.3 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.1 | 1.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.1 | 2.3 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.1 | 12.1 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 1.9 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.1 | 30.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.1 | 1.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.8 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 1.0 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
| 0.1 | 0.9 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 1.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 1.3 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.1 | 1.5 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.1 | 0.5 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.1 | 0.7 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.1 | 2.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 1.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 5.0 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 3.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 3.1 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 0.9 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.1 | 1.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 0.1 | 1.6 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.1 | 3.2 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 0.2 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.1 | 7.7 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.1 | 1.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.2 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) |
| 0.1 | 0.4 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 0.3 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.1 | 1.6 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 0.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 2.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.4 | GO:0001594 | trace-amine receptor activity(GO:0001594) |
| 0.0 | 13.3 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.3 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.0 | 15.2 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 0.3 | GO:1902282 | voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282) |
| 0.0 | 1.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 6.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 2.5 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 1.6 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.9 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.0 | 1.5 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 1.2 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.2 | GO:0052655 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.0 | 0.1 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
| 0.0 | 0.7 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 15.4 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 1.4 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 0.8 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 1.6 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 1.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 3.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 2.2 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.0 | 0.3 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.6 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.0 | 0.7 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.8 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 1.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.1 | GO:0015068 | amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068) |
| 0.0 | 1.9 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 5.1 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 1.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.2 | GO:0030983 | mismatched DNA binding(GO:0030983) |
| 0.0 | 0.1 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.0 | 0.6 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 1.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.7 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.1 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.0 | 0.5 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.2 | GO:0005179 | hormone activity(GO:0005179) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 6.2 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.2 | 3.5 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.2 | 15.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.2 | 9.0 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.1 | 13.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 5.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 3.8 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 1.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 1.4 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 6.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 3.6 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 3.6 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.2 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.5 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 2.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.5 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 1.4 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 1.9 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.9 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 0.8 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 0.4 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.7 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.6 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 1.2 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 13.2 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.2 | 12.0 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 4.5 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 7.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.2 | 5.9 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.1 | 2.5 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 2.2 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 3.6 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.1 | 1.7 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 11.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 2.8 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.1 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.1 | 3.4 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 9.0 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 3.6 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 1.2 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 2.2 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 6.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 2.0 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 0.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.1 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 1.2 | REACTOME REGULATION OF INSULIN SECRETION | Genes involved in Regulation of Insulin Secretion |
| 0.0 | 1.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.5 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.5 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 2.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.2 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 4.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.6 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 0.9 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.0 | 1.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 1.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.5 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 2.3 | REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | Genes involved in Cell surface interactions at the vascular wall |
| 0.0 | 1.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.0 | 1.1 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 0.8 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |