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Illumina Body Map 2: averaged replicates

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Results for RFX7_RFX4_RFX1

Z-value: 7.99

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Transcription factors associated with RFX7_RFX4_RFX1

Gene Symbol Gene ID Gene Info
ENSG00000181827.10 regulatory factor X7
ENSG00000111783.8 regulatory factor X4
ENSG00000132005.4 regulatory factor X1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX4hg19_v2_chr12_+_106994905_1069949540.723.2e-06Click!
RFX1hg19_v2_chr19_-_14117074_141171410.327.6e-02Click!
RFX7hg19_v2_chr15_-_56535464_565355210.261.5e-01Click!

Activity profile of RFX7_RFX4_RFX1 motif

Sorted Z-values of RFX7_RFX4_RFX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_55888186 33.78 ENST00000291934.3
transmembrane protein 190
chr1_-_109655377 31.80 ENST00000369948.3
chromosome 1 open reading frame 194
chr1_-_109655355 30.33 ENST00000369945.3
chromosome 1 open reading frame 194
chr10_+_23216944 27.70 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
armadillo repeat containing 3
chr1_+_36549676 27.67 ENST00000207457.3
tektin 2 (testicular)
chr5_-_7851260 24.92 ENST00000509627.1
chromosome 5 open reading frame 49
chr22_-_23484246 23.94 ENST00000216036.4
rhabdoid tumor deletion region gene 1
chr2_+_54558004 23.55 ENST00000405749.1
ENST00000398634.2
ENST00000447328.1
chromosome 2 open reading frame 73
chr2_-_170550877 23.23 ENST00000447353.1
coiled-coil domain containing 173
chr10_+_23217006 22.76 ENST00000376528.4
ENST00000447081.1
armadillo repeat containing 3
chr10_-_25305011 22.76 ENST00000331161.4
ENST00000376363.1
enkurin, TRPC channel interacting protein
chr16_+_80574854 22.04 ENST00000305904.6
ENST00000568035.1
dynein, light chain, roadblock-type 2
chr2_-_170550842 21.03 ENST00000421028.1
coiled-coil domain containing 173
chr8_-_67940755 20.85 ENST00000324682.5
protein phosphatase 1, regulatory subunit 42
chr2_-_196933536 20.45 ENST00000312428.6
ENST00000410072.1
dynein, axonemal, heavy chain 7
chr1_-_205391178 18.95 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr1_+_85527987 18.79 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
WD repeat domain 63
chr1_+_43613612 18.38 ENST00000335282.4
family with sequence similarity 183, member A
chr12_+_119772502 18.10 ENST00000536742.1
ENST00000327554.2
coiled-coil domain containing 60
chr6_+_163148973 17.20 ENST00000366888.2
PARK2 co-regulated
chr17_+_72270429 17.02 ENST00000311014.6
dynein, axonemal, intermediate chain 2
chr10_+_15001430 16.98 ENST00000407572.1
meiosis/spermiogenesis associated 1
chr17_+_45908974 16.78 ENST00000269025.4
leucine rich repeat containing 46
chr20_+_56725952 16.22 ENST00000371168.3
chromosome 20 open reading frame 85
chr5_-_137475071 15.90 ENST00000265191.2
NME/NM23 family member 5
chr10_-_25304889 15.16 ENST00000483339.2
enkurin, TRPC channel interacting protein
chr17_+_72270380 14.98 ENST00000582036.1
ENST00000307504.5
dynein, axonemal, intermediate chain 2
chr8_+_15397732 14.63 ENST00000382020.4
ENST00000506802.1
ENST00000509380.1
ENST00000503731.1
tumor suppressor candidate 3
chr17_+_11501748 14.41 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr17_+_42977122 14.22 ENST00000412523.2
ENST00000331733.4
ENST00000417826.2
family with sequence similarity 187, member A
coiled-coil domain containing 103
chr17_+_42977062 14.09 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
coiled-coil domain containing 103
chr9_-_138391692 14.00 ENST00000429260.2
chromosome 9 open reading frame 116
chr1_-_169396666 13.59 ENST00000456107.1
ENST00000367805.3
coiled-coil domain containing 181
chr9_+_130478345 13.47 ENST00000373289.3
ENST00000393748.4
tetratricopeptide repeat domain 16
chr2_+_26624775 12.92 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr11_+_61248583 12.92 ENST00000432063.2
ENST00000338608.2
protein phosphatase 1, regulatory subunit 32
chr1_-_169396646 12.91 ENST00000367806.3
coiled-coil domain containing 181
chr19_+_2096868 12.82 ENST00000395296.1
ENST00000395301.3
IZUMO family member 4
chr8_-_101118185 12.42 ENST00000523437.1
regulator of G-protein signaling 22
chr1_+_43613566 12.35 ENST00000409396.1
family with sequence similarity 183, member A
chr21_-_43916296 12.29 ENST00000398352.3
radial spoke head 1 homolog (Chlamydomonas)
chr9_-_34381536 12.28 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
chromosome 9 open reading frame 24
chrX_+_23925918 12.11 ENST00000379211.3
chromosome X open reading frame 58
chr1_+_43637996 12.05 ENST00000528956.1
ENST00000529956.1
WD repeat domain 65
chr2_+_26785409 11.72 ENST00000329615.3
ENST00000409392.1
chromosome 2 open reading frame 70
chr15_+_74610894 11.71 ENST00000558821.1
ENST00000268082.4
coiled-coil domain containing 33
chr17_+_73642486 11.53 ENST00000579469.1
small integral membrane protein 6
chr7_-_123174610 11.39 ENST00000324698.6
ENST00000434450.1
IQ motif and ubiquitin domain containing
chr17_+_73642315 11.37 ENST00000556126.2
small integral membrane protein 6
chr21_-_43916433 11.35 ENST00000291536.3
radial spoke head 1 homolog (Chlamydomonas)
chr1_-_118727781 11.29 ENST00000336338.5
sperm associated antigen 17
chr10_+_118608998 10.92 ENST00000409522.1
ENST00000341276.5
ENST00000512864.2
enolase family member 4
chr19_-_46974741 10.69 ENST00000313683.10
ENST00000602246.1
paraneoplastic Ma antigen family-like 1
chr19_-_11545920 10.58 ENST00000356392.4
ENST00000591179.1
coiled-coil domain containing 151
chr4_-_177116772 10.52 ENST00000280191.2
spermatogenesis associated 4
chrX_+_133371077 10.51 ENST00000517294.1
ENST00000370809.4
coiled-coil domain containing 160
chr12_-_113658892 10.27 ENST00000299732.2
ENST00000416617.2
IQ motif containing D
chr17_+_17876127 10.26 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr17_+_11501816 10.25 ENST00000454412.2
dynein, axonemal, heavy chain 9
chr9_-_34381511 10.22 ENST00000379124.1
chromosome 9 open reading frame 24
chr12_+_122667658 10.20 ENST00000339777.4
ENST00000425921.1
leucine rich repeat containing 43
chr9_+_34458771 10.10 ENST00000437363.1
ENST00000242317.4
dynein, axonemal, intermediate chain 1
chr8_-_101117847 9.81 ENST00000523287.1
ENST00000519092.1
regulator of G-protein signaling 22
chr19_-_46974664 9.73 ENST00000438932.2
paraneoplastic Ma antigen family-like 1
chr3_-_10149907 9.67 ENST00000450660.2
ENST00000524279.1
FANCD2 opposite strand
chr4_+_146601356 9.60 ENST00000438731.1
ENST00000511965.1
chromosome 4 open reading frame 51
chr17_-_15244894 9.57 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
tektin 3
chr5_-_121659052 9.57 ENST00000512105.1
CTD-2544H17.1
chr4_-_56458374 9.34 ENST00000295645.4
phosducin-like 2
chr1_-_45308616 9.14 ENST00000447098.2
ENST00000372192.3
patched 2
chr17_+_48585745 9.11 ENST00000323776.5
MYCBP associated protein
chr8_+_144798429 8.88 ENST00000338033.4
ENST00000395107.4
ENST00000395108.2
mitogen-activated protein kinase 15
chr12_-_113658826 8.82 ENST00000546692.1
IQ motif containing D
chr10_-_82116467 8.75 ENST00000454362.1
DPY30 domain containing 1
chr12_+_96883347 8.74 ENST00000524981.4
ENST00000298953.3
chromosome 12 open reading frame 55
chr17_-_8648105 8.64 ENST00000539522.2
ENST00000293845.3
coiled-coil domain containing 42
chr12_+_119772734 8.51 ENST00000539847.1
coiled-coil domain containing 60
chr1_-_60539422 8.47 ENST00000371201.3
chromosome 1 open reading frame 87
chr3_-_167098059 8.41 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
zinc finger, B-box domain containing
chr8_-_101118210 8.41 ENST00000360863.6
regulator of G-protein signaling 22
chr1_-_60539405 8.36 ENST00000450089.2
chromosome 1 open reading frame 87
chr6_+_116937636 8.31 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
radial spoke head 4 homolog A (Chlamydomonas)
chr8_+_10530133 8.29 ENST00000304519.5
chromosome 8 open reading frame 74
chr2_+_84743562 8.21 ENST00000389394.3
ENST00000398278.2
dynein, axonemal, heavy chain 6
chr22_+_45809560 8.18 ENST00000342894.3
ENST00000538017.1
RIB43A domain with coiled-coils 2
chr1_-_75139397 8.17 ENST00000326665.5
chromosome 1 open reading frame 173
chr1_+_161068179 8.00 ENST00000368011.4
ENST00000392192.2
kelch domain containing 9
chr10_-_82116505 7.96 ENST00000372202.1
ENST00000421924.2
ENST00000453477.1
DPY30 domain containing 1
chr16_-_85146040 7.75 ENST00000539556.1
family with sequence similarity 92, member B
chr1_-_1935153 7.66 ENST00000434971.2
chromosome 1 open reading frame 222
chr15_+_67547113 7.56 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr1_+_115642293 7.42 ENST00000448680.1
RP4-666F24.3
chr5_-_110074603 7.41 ENST00000515278.2
transmembrane protein 232
chr15_-_55790515 7.41 ENST00000448430.2
ENST00000457155.2
dyslexia susceptibility 1 candidate 1
chr17_+_48585902 7.33 ENST00000452039.1
MYCBP associated protein
chr8_-_11324273 7.28 ENST00000284486.4
family with sequence similarity 167, member A
chr11_+_86085778 7.08 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
coiled-coil domain containing 81
chr11_-_85397167 7.06 ENST00000316398.3
coiled-coil domain containing 89
chr13_-_103046837 6.98 ENST00000607251.1
FGF14 intronic transcript 1 (non-protein coding)
chr17_+_48585958 6.93 ENST00000436259.2
MYCBP associated protein
chr6_-_165723088 6.91 ENST00000230301.8
chromosome 6 open reading frame 118
chr14_+_96858433 6.87 ENST00000267584.4
adenylate kinase 7
chr4_+_176987131 6.79 ENST00000280190.4
WD repeat domain 17
chr6_-_24799117 6.75 ENST00000565469.1
chromosome 6 open reading frame 229
chr11_+_71791803 6.70 ENST00000539271.1
leucine rich transmembrane and O-methyltransferase domain containing
chr17_-_60885700 6.64 ENST00000583600.1
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr17_-_60885645 6.61 ENST00000544856.2
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr5_-_110062349 6.60 ENST00000511883.2
ENST00000455884.2
transmembrane protein 232
chr9_+_34458851 6.55 ENST00000545019.1
dynein, axonemal, intermediate chain 1
chr1_+_64669294 6.53 ENST00000371077.5
ubiquitin-conjugating enzyme E2U (putative)
chr9_+_72435709 6.44 ENST00000377197.3
ENST00000527647.1
chromosome 9 open reading frame 135
chr11_+_6260298 6.42 ENST00000379936.2
cyclic nucleotide gated channel alpha 4
chr15_+_67547163 6.38 ENST00000335894.4
IQ motif containing H
chr17_-_60885659 6.34 ENST00000311269.5
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr10_+_82116529 6.33 ENST00000411538.1
ENST00000256039.2
DPY30 domain containing 2
chr22_-_45809495 6.29 ENST00000404354.3
structural maintenance of chromosomes 1B
chr19_+_55996543 6.25 ENST00000591590.1
N-acetyltransferase 14 (GCN5-related, putative)
chr1_+_206809113 6.23 ENST00000441486.1
ENST00000367106.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chrX_-_114252193 6.23 ENST00000243213.1
interleukin 13 receptor, alpha 2
chr9_+_130469257 6.22 ENST00000373295.2
chromosome 9 open reading frame 117
chr1_-_85156417 6.08 ENST00000422026.1
synovial sarcoma, X breakpoint 2 interacting protein
chr3_-_19975665 6.07 ENST00000295824.9
ENST00000389256.4
EF-hand domain family, member B
chr7_-_105221898 5.95 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EF-hand calcium binding domain 10
chr1_+_1981890 5.94 ENST00000378567.3
ENST00000468310.1
protein kinase C, zeta
chr10_+_106113515 5.89 ENST00000369704.3
ENST00000312902.5
coiled-coil domain containing 147
chr6_+_147091575 5.87 ENST00000326916.8
ENST00000470716.2
ENST00000367488.1
androglobin
chr18_-_47792851 5.83 ENST00000398545.4
coiled-coil domain containing 11
chr11_-_8954491 5.75 ENST00000526227.1
ENST00000525780.1
ENST00000326053.5
chromosome 11 open reading frame 16
chr6_+_146920097 5.73 ENST00000397944.3
ENST00000522242.1
androglobin
chr20_+_30467600 5.61 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr4_+_81256871 5.60 ENST00000358105.3
ENST00000508675.1
chromosome 4 open reading frame 22
chr8_+_94767109 5.59 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
transmembrane protein 67
chr4_-_156297949 5.58 ENST00000515654.1
microtubule-associated protein 9
chr9_-_117267717 5.57 ENST00000374057.3
deafness, autosomal recessive 31
chr3_-_48659193 5.52 ENST00000330862.3
transmembrane protein 89
chr20_-_44420507 5.52 ENST00000243938.4
WAP four-disulfide core domain 3
chr5_-_110062384 5.48 ENST00000429839.2
transmembrane protein 232
chr3_+_63638339 5.43 ENST00000343837.3
ENST00000469440.1
sentan, cilia apical structure protein
chr15_+_40531621 5.42 ENST00000560346.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_111889212 5.41 ENST00000369737.4
primary cilia formation
chr15_+_40531243 5.41 ENST00000558055.1
ENST00000455577.2
p21 protein (Cdc42/Rac)-activated kinase 6
chr12_+_49297899 5.41 ENST00000552942.1
ENST00000320516.4
coiled-coil domain containing 65
chr4_+_2420659 5.39 ENST00000382849.2
RP11-503N18.1
chr5_+_132149017 5.35 ENST00000378693.2
sosondowah ankyrin repeat domain family member A
chr14_+_105452094 5.33 ENST00000551606.1
ENST00000547315.1
chromosome 14 open reading frame 79
chr4_+_176986978 5.31 ENST00000508596.1
ENST00000393643.2
WD repeat domain 17
chr17_+_42733730 5.28 ENST00000359945.3
ENST00000425535.1
chromosome 17 open reading frame 104
chr1_-_36916011 5.28 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
organic solute carrier partner 1
chr12_+_85430110 5.15 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chrX_+_35937843 5.15 ENST00000297866.5
chromosome X open reading frame 22
chr12_-_100660833 5.12 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
DEP domain containing 4
chr10_-_28287968 5.10 ENST00000305242.5
armadillo repeat containing 4
chr8_+_94767072 5.09 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
transmembrane protein 67
chr16_-_30064244 5.09 ENST00000571269.1
ENST00000561666.1
family with sequence similarity 57, member B
chr19_+_751122 5.08 ENST00000215582.6
mitotic spindle positioning
chr1_-_40157345 5.05 ENST00000372844.3
hippocalcin like 4
chr1_-_21044489 5.02 ENST00000247986.2
kinesin family member 17
chr5_+_127039075 5.01 ENST00000514853.2
CTC-228N24.1
chr16_-_30773372 4.99 ENST00000545825.1
ENST00000541260.1
chromosome 16 open reading frame 93
chr11_-_47736896 4.94 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
ATP/GTP binding protein-like 2
chr11_+_124543694 4.93 ENST00000227135.2
ENST00000532692.1
sperm autoantigenic protein 17
chrX_-_44202857 4.93 ENST00000420999.1
EF-hand domain (C-terminal) containing 2
chr17_+_54230819 4.86 ENST00000318698.2
ENST00000566473.2
ankyrin-repeat and fibronectin type III domain containing 1
chr1_+_111888890 4.85 ENST00000369738.4
primary cilia formation
chr7_-_36406750 4.84 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
chr1_+_20512568 4.83 ENST00000375099.3
UBX domain protein 10
chr1_-_36915880 4.81 ENST00000445843.3
organic solute carrier partner 1
chr10_-_82116497 4.79 ENST00000372204.3
DPY30 domain containing 1
chr9_+_72435749 4.76 ENST00000480564.1
chromosome 9 open reading frame 135
chr11_-_8615488 4.76 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
serine/threonine kinase 33
chr2_+_202937972 4.69 ENST00000541917.1
ENST00000295844.3
uncharacterized protein KIAA2012
chr1_-_36916066 4.68 ENST00000315643.9
organic solute carrier partner 1
chr1_+_32674675 4.64 ENST00000409358.1
doublecortin domain containing 2B
chr10_-_134756030 4.61 ENST00000368586.5
ENST00000368582.2
tetratricopeptide repeat domain 40
chr19_+_55996316 4.57 ENST00000205194.4
N-acetyltransferase 14 (GCN5-related, putative)
chr6_+_146920116 4.56 ENST00000367493.3
androglobin
chr11_-_8615687 4.53 ENST00000534493.1
ENST00000422559.2
serine/threonine kinase 33
chr3_+_39149145 4.52 ENST00000301819.6
ENST00000431162.2
tetratricopeptide repeat domain 21A
chr5_-_54529415 4.52 ENST00000282572.4
cyclin O
chr7_+_12544025 4.49 ENST00000443874.1
ENST00000424453.1
AC005281.1
chr6_-_49755019 4.48 ENST00000304801.3
phosphoglycerate kinase 2
chr2_-_207630033 4.41 ENST00000449792.1
malate dehydrogenase 1B, NAD (soluble)
chr1_+_206808868 4.41 ENST00000367109.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr2_-_207629997 4.38 ENST00000454776.2
malate dehydrogenase 1B, NAD (soluble)
chr8_-_101118439 4.36 ENST00000519408.1
regulator of G-protein signaling 22
chr21_+_18885318 4.35 ENST00000400166.1
coxsackie virus and adenovirus receptor
chr3_+_39149298 4.33 ENST00000440121.1
tetratricopeptide repeat domain 21A
chr4_-_153700864 4.32 ENST00000304337.2
tigger transposable element derived 4
chr1_+_206808918 4.32 ENST00000367108.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr1_+_1109272 4.30 ENST00000379290.1
ENST00000379289.1
tubulin tyrosine ligase-like family, member 10
chr2_-_220110187 4.28 ENST00000295759.7
ENST00000392089.2
galactosidase, beta 1-like
chr4_+_100432161 4.26 ENST00000326581.4
ENST00000514652.1
chromosome 4 open reading frame 17
chr1_-_74663825 4.21 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
leucine-rich repeats and IQ motif containing 3
chr12_+_13061894 4.20 ENST00000540125.1
G protein-coupled receptor, family C, group 5, member A
chr11_-_8615720 4.18 ENST00000358872.3
ENST00000454443.2
serine/threonine kinase 33
chr5_+_121465234 4.09 ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr14_+_75536280 4.00 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr6_-_43478239 4.00 ENST00000372441.1
leucine rich repeat containing 73
chr5_+_121465207 3.95 ENST00000296600.4
zinc finger protein 474
chrX_-_115828156 3.93 ENST00000446495.1
RP11-232D9.3

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX7_RFX4_RFX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 67.4 GO:0036158 outer dynein arm assembly(GO:0036158)
4.2 76.4 GO:0036159 inner dynein arm assembly(GO:0036159)
4.1 8.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
3.1 6.2 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
3.0 15.0 GO:0035617 stress granule disassembly(GO:0035617)
2.8 14.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
2.1 6.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
1.9 9.6 GO:0080154 regulation of fertilization(GO:0080154)
1.9 5.7 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
1.9 9.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
1.9 16.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
1.8 34.4 GO:0003351 epithelial cilium movement(GO:0003351)
1.6 38.3 GO:0003341 cilium movement(GO:0003341)
1.4 23.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.3 7.8 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.3 5.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
1.2 14.9 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
1.2 3.7 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
1.1 21.7 GO:0035082 axoneme assembly(GO:0035082)
1.1 3.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
1.0 3.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
1.0 3.0 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.0 72.0 GO:0042073 intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840)
1.0 7.8 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.9 14.6 GO:0015693 magnesium ion transport(GO:0015693)
0.7 4.3 GO:0018094 protein polyglycylation(GO:0018094)
0.7 3.5 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.7 2.0 GO:0016999 antibiotic metabolic process(GO:0016999)
0.7 9.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 5.6 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.6 12.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.6 2.3 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.6 1.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.5 2.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.5 10.7 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.5 3.6 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.5 8.8 GO:0006108 malate metabolic process(GO:0006108)
0.5 2.6 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.5 5.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.5 5.9 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.5 2.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.5 6.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5 3.6 GO:0007341 penetration of zona pellucida(GO:0007341)
0.4 5.9 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.4 2.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.4 2.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.4 1.1 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.4 1.8 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 6.2 GO:0002638 negative regulation of immunoglobulin production(GO:0002638)
0.3 6.9 GO:0001675 acrosome assembly(GO:0001675)
0.3 0.9 GO:1902871 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.3 1.2 GO:1905154 negative regulation of synaptic vesicle recycling(GO:1903422) negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.3 8.6 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.3 1.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 2.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.3 0.9 GO:0006173 dADP biosynthetic process(GO:0006173)
0.3 1.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 0.8 GO:0097106 postsynaptic density organization(GO:0097106)
0.3 0.5 GO:0061053 somite development(GO:0061053)
0.3 1.4 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 2.4 GO:0007506 gonadal mesoderm development(GO:0007506)
0.3 1.6 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.3 1.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 1.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.3 0.8 GO:0001694 histamine biosynthetic process(GO:0001694)
0.3 0.8 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.9 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 32.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.2 2.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 2.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 1.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 3.8 GO:0030317 sperm motility(GO:0030317)
0.2 8.7 GO:0071801 regulation of podosome assembly(GO:0071801)
0.2 0.2 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
0.2 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 1.5 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.2 2.0 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.4 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.2 30.2 GO:0007286 spermatid development(GO:0007286)
0.2 1.9 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 10.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.2 1.0 GO:0050893 sensory processing(GO:0050893)
0.2 3.2 GO:0045475 locomotor rhythm(GO:0045475)
0.2 5.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.2 5.5 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.4 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 2.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 2.3 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 2.8 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 2.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.1 4.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.1 1.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.4 GO:0021997 neural plate axis specification(GO:0021997)
0.1 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 1.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 1.7 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 1.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.9 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 1.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.3 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.3 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 1.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 1.2 GO:0015705 iodide transport(GO:0015705)
0.1 3.5 GO:0042407 cristae formation(GO:0042407)
0.1 0.3 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 14.4 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 3.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 2.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.5 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 1.5 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 3.6 GO:0006739 NADP metabolic process(GO:0006739)
0.1 9.9 GO:0007062 sister chromatid cohesion(GO:0007062)
0.1 1.0 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.1 GO:2000582 regulation of microtubule motor activity(GO:2000574) positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.8 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.4 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.6 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 3.6 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 2.5 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 3.6 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 1.6 GO:0007635 chemosensory behavior(GO:0007635)
0.0 19.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.8 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 2.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.5 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 3.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 1.3 GO:0002021 response to dietary excess(GO:0002021)
0.0 3.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 10.1 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.5 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374)
0.0 1.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.3 GO:0050686 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 1.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.5 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 9.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 2.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.6 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 2.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 10.8 GO:0007608 sensory perception of smell(GO:0007608)
0.0 1.6 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 1.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 18.9 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.2 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0007369 gastrulation(GO:0007369)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 1.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.1 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 5.8 GO:0021915 neural tube development(GO:0021915)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0007099 centriole replication(GO:0007099)
0.0 0.4 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 3.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0010165 response to X-ray(GO:0010165)
0.0 0.4 GO:0048511 rhythmic process(GO:0048511)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:2001178 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.8 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 2.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.2 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 1.3 GO:0001942 hair follicle development(GO:0001942)
0.0 1.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 3.2 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.9 GO:0006338 chromatin remodeling(GO:0006338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
6.8 33.8 GO:0002079 inner acrosomal membrane(GO:0002079)
6.1 48.8 GO:0002177 manchette(GO:0002177)
5.7 73.8 GO:0036157 outer dynein arm(GO:0036157)
4.9 14.6 GO:1990716 axonemal central apparatus(GO:1990716)
3.3 16.7 GO:0036156 inner dynein arm(GO:0036156)
2.8 8.3 GO:0001534 radial spoke(GO:0001534)
2.1 8.2 GO:0005858 axonemal dynein complex(GO:0005858)
1.8 5.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.7 23.9 GO:0072687 meiotic spindle(GO:0072687)
1.7 10.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.2 3.7 GO:0042585 germinal vesicle(GO:0042585)
1.2 10.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.2 4.8 GO:0016939 kinesin II complex(GO:0016939)
1.1 4.5 GO:0035686 sperm fibrous sheath(GO:0035686)
1.0 28.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.0 43.9 GO:0097228 sperm principal piece(GO:0097228)
1.0 17.2 GO:0097225 sperm midpiece(GO:0097225)
0.9 140.1 GO:0031514 motile cilium(GO:0031514)
0.9 14.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.7 8.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.7 13.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.7 2.8 GO:0070985 TFIIK complex(GO:0070985)
0.7 14.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.7 3.4 GO:0005879 axonemal microtubule(GO:0005879)
0.6 12.8 GO:0036038 MKS complex(GO:0036038)
0.5 52.9 GO:0036064 ciliary basal body(GO:0036064)
0.4 2.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.4 3.5 GO:0061617 MICOS complex(GO:0061617)
0.4 6.2 GO:0005883 neurofilament(GO:0005883)
0.4 6.5 GO:0031209 SCAR complex(GO:0031209)
0.3 4.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 5.9 GO:0045179 apical cortex(GO:0045179)
0.3 1.0 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 11.7 GO:0097546 ciliary base(GO:0097546)
0.3 14.3 GO:0030286 dynein complex(GO:0030286)
0.3 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.0 GO:0098536 deuterosome(GO:0098536)
0.2 14.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 16.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.2 9.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 7.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.2 2.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 5.7 GO:0071565 nBAF complex(GO:0071565)
0.2 3.8 GO:0043209 myelin sheath(GO:0043209)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 14.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 12.7 GO:0005871 kinesin complex(GO:0005871)
0.1 1.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 35.9 GO:0005929 cilium(GO:0005929)
0.1 2.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 2.6 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.1 4.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 5.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 3.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.6 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 1.0 GO:0043195 terminal bouton(GO:0043195)
0.1 3.3 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 3.0 GO:0005938 cell cortex(GO:0005938)
0.0 11.0 GO:0001650 fibrillar center(GO:0001650)
0.0 7.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 5.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 4.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 1.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.8 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0098858 actin-based cell projection(GO:0098858)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 74.2 GO:0045504 dynein heavy chain binding(GO:0045504)
2.2 71.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
2.1 6.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.0 6.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
2.0 6.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
1.5 4.5 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.5 10.4 GO:0004127 cytidylate kinase activity(GO:0004127)
1.4 8.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.4 12.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.3 9.1 GO:0005119 smoothened binding(GO:0005119)
1.2 10.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.0 8.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.9 28.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.9 5.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.9 14.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.7 6.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.7 3.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.7 2.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.7 7.8 GO:0071253 connexin binding(GO:0071253)
0.6 17.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.6 12.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.6 7.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.6 4.5 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.5 1.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.5 3.7 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.4 31.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.4 1.7 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 4.3 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.4 15.2 GO:0070840 dynein complex binding(GO:0070840)
0.3 32.3 GO:0043621 protein self-association(GO:0043621)
0.3 10.7 GO:0031005 filamin binding(GO:0031005)
0.3 3.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.3 15.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 3.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.3 5.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.3 1.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.3 1.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 8.9 GO:0004707 MAP kinase activity(GO:0004707)
0.2 5.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 5.9 GO:0043274 phospholipase binding(GO:0043274)
0.2 2.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 2.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 7.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 7.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 7.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 5.4 GO:0030332 cyclin binding(GO:0030332)
0.2 1.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 13.3 GO:0003777 microtubule motor activity(GO:0003777)
0.2 2.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 3.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 4.3 GO:0016805 dipeptidase activity(GO:0016805)
0.2 11.0 GO:0030552 cAMP binding(GO:0030552)
0.2 5.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.4 GO:0019778 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 10.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.3 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 2.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 12.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.9 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 30.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 1.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.5 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.7 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 5.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 3.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 3.1 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 1.1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 3.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 7.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.4 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 1.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 2.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 13.3 GO:0008017 microtubule binding(GO:0008017)
0.0 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 15.2 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 1.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 6.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.6 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 15.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 1.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.2 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 5.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.2 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 3.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 15.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 9.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 13.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 5.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 1.2 PID ATR PATHWAY ATR signaling pathway
0.1 1.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 6.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 3.6 PID BMP PATHWAY BMP receptor signaling
0.0 3.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 2.5 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID MYC PATHWAY C-MYC pathway
0.0 1.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 12.0 REACTOME KINESINS Genes involved in Kinesins
0.2 4.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.2 7.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 5.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 2.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 3.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 11.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 3.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 9.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 3.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 6.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.2 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 1.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 4.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.9 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins