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Illumina Body Map 2: averaged replicates

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Results for RORA

Z-value: 1.11

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Transcription factors associated with RORA

Gene Symbol Gene ID Gene Info
RORA
ENSG00000069667.11 RAR related orphan receptor A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORAhg19_v2_chr15_-_60884706_608847430.336.8e-02Click!

Activity profile of RORA motif

Sorted Z-values of RORA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_104408032 2.54 ENST00000455348.2
RD3L
retinal degeneration 3-like
chr21_-_46330545 2.45 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_+_31366536 1.84 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr1_-_153522562 1.83 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr14_-_104408645 1.67 ENST00000557640.1
RD3L
retinal degeneration 3-like
chr1_+_206858328 1.62 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr18_-_56296182 1.61 ENST00000361673.3
ALPK2
alpha-kinase 2
chr19_-_49140609 1.60 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr8_-_134072593 1.56 ENST00000427060.2
SLA
Src-like-adaptor
chr17_+_4855053 1.55 ENST00000518175.1
ENO3
enolase 3 (beta, muscle)
chr10_+_77056134 1.49 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr19_-_39826639 1.49 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr11_+_128563652 1.40 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr16_+_31366455 1.38 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr6_-_33297013 1.37 ENST00000453407.1
DAXX
death-domain associated protein
chr7_-_142198049 1.35 ENST00000471935.1
TRBV11-2
T cell receptor beta variable 11-2
chr1_+_29213678 1.31 ENST00000347529.3
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr6_+_167525277 1.29 ENST00000400926.2
CCR6
chemokine (C-C motif) receptor 6
chr6_+_36839616 1.24 ENST00000359359.2
ENST00000510325.2
C6orf89
chromosome 6 open reading frame 89
chr11_-_64511575 1.23 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_28303804 1.19 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chr16_-_4164027 1.18 ENST00000572288.1
ADCY9
adenylate cyclase 9
chr9_-_35103105 1.16 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chr10_+_81065975 1.15 ENST00000446377.2
ZMIZ1
zinc finger, MIZ-type containing 1
chrX_-_129299638 1.14 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr6_-_41703296 1.13 ENST00000373033.1
TFEB
transcription factor EB
chr6_+_53948221 1.10 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr3_+_46449049 1.09 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr14_+_22995812 1.08 ENST00000390520.1
TRAJ17
T cell receptor alpha joining 17
chr9_+_74920408 1.08 ENST00000451152.1
RP11-63P12.6
RP11-63P12.6
chr4_+_106067943 1.07 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr20_+_3776936 1.06 ENST00000439880.2
CDC25B
cell division cycle 25B
chr1_-_154164534 1.05 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr22_-_24110063 1.04 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr8_-_116673894 1.04 ENST00000395713.2
TRPS1
trichorhinophalangeal syndrome I
chr9_+_74920335 1.01 ENST00000451596.2
ENST00000436054.1
RP11-63P12.6
RP11-63P12.6
chr2_+_219472637 1.01 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr14_-_107114267 1.00 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr17_+_74075263 0.95 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr20_+_3776371 0.95 ENST00000245960.5
CDC25B
cell division cycle 25B
chr1_-_211752073 0.95 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr10_+_104178946 0.93 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr10_-_65028817 0.93 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr6_+_53948328 0.93 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr1_-_85040090 0.93 ENST00000370630.5
CTBS
chitobiase, di-N-acetyl-
chr11_-_119599794 0.92 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr16_-_88717423 0.90 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr1_+_206858232 0.88 ENST00000294981.4
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr11_-_64511789 0.87 ENST00000419843.1
ENST00000394430.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr1_+_43148625 0.87 ENST00000436427.1
YBX1
Y box binding protein 1
chr3_-_18480173 0.87 ENST00000414509.1
SATB1
SATB homeobox 1
chr16_-_69390209 0.84 ENST00000563634.1
RP11-343C2.9
Uncharacterized protein
chr14_+_22978168 0.83 ENST00000390505.1
TRAJ32
T cell receptor alpha joining 32
chr5_+_149865377 0.82 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr5_+_142286887 0.82 ENST00000451259.1
ARHGAP26
Rho GTPase activating protein 26
chr7_+_66395596 0.79 ENST00000424964.2
ENST00000418375.1
TMEM248
transmembrane protein 248
chr11_+_111957497 0.79 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr3_-_18480260 0.79 ENST00000454909.2
SATB1
SATB homeobox 1
chr16_+_21964662 0.79 ENST00000561553.1
ENST00000565331.1
UQCRC2
ubiquinol-cytochrome c reductase core protein II
chr3_+_52813932 0.78 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr12_+_72080253 0.78 ENST00000549735.1
TMEM19
transmembrane protein 19
chrX_+_153770421 0.78 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr11_-_6462210 0.77 ENST00000265983.3
HPX
hemopexin
chr10_+_75757863 0.77 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr9_-_130966497 0.77 ENST00000393608.1
ENST00000372948.3
CIZ1
CDKN1A interacting zinc finger protein 1
chr9_+_134103496 0.75 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr18_-_19284724 0.74 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr11_-_118272610 0.74 ENST00000534438.1
RP11-770J1.5
Uncharacterized protein
chr19_+_46850251 0.74 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr2_+_219472488 0.73 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chr7_+_123241908 0.71 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr10_+_77056181 0.70 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr7_-_140179276 0.69 ENST00000443720.2
ENST00000255977.2
MKRN1
makorin ring finger protein 1
chr16_+_691792 0.68 ENST00000307650.4
FAM195A
family with sequence similarity 195, member A
chr11_+_118272328 0.67 ENST00000524422.1
ATP5L
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G
chr19_-_39926268 0.67 ENST00000599705.1
RPS16
ribosomal protein S16
chr6_-_9933500 0.66 ENST00000492169.1
OFCC1
orofacial cleft 1 candidate 1
chr3_+_46448648 0.66 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr19_+_1248547 0.66 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr3_-_52312337 0.65 ENST00000469000.1
WDR82
WD repeat domain 82
chr9_+_112852477 0.65 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr13_-_52026730 0.65 ENST00000420668.2
INTS6
integrator complex subunit 6
chr19_+_46850320 0.65 ENST00000391919.1
PPP5C
protein phosphatase 5, catalytic subunit
chr2_-_86422095 0.64 ENST00000254636.5
IMMT
inner membrane protein, mitochondrial
chr19_+_8478154 0.64 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr1_+_9294822 0.63 ENST00000377403.2
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_+_107077435 0.63 ENST00000369046.4
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr2_-_207024134 0.62 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr6_+_107077471 0.62 ENST00000369044.1
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr19_-_55669093 0.60 ENST00000344887.5
TNNI3
troponin I type 3 (cardiac)
chr17_-_10450866 0.60 ENST00000578017.1
MYH2
myosin, heavy chain 2, skeletal muscle, adult
chr10_-_65028938 0.60 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chrX_-_21776281 0.59 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr12_+_109577202 0.59 ENST00000377848.3
ENST00000377854.5
ACACB
acetyl-CoA carboxylase beta
chr8_+_37553261 0.59 ENST00000331569.4
ZNF703
zinc finger protein 703
chr19_-_11689752 0.59 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr15_-_72767490 0.58 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr10_+_72575643 0.57 ENST00000373202.3
SGPL1
sphingosine-1-phosphate lyase 1
chr15_-_53002007 0.57 ENST00000561490.1
FAM214A
family with sequence similarity 214, member A
chr3_-_141747950 0.56 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr3_-_49158312 0.56 ENST00000398892.3
ENST00000453664.1
ENST00000398888.2
USP19
ubiquitin specific peptidase 19
chr1_+_161172143 0.55 ENST00000476409.2
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr17_-_4889508 0.55 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr9_-_86322516 0.55 ENST00000529923.1
UBQLN1
ubiquilin 1
chr11_-_67271723 0.54 ENST00000533391.1
ENST00000534749.1
ENST00000532703.1
PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr4_-_186732241 0.54 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr3_-_113465065 0.54 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr10_+_81107271 0.54 ENST00000448165.1
PPIF
peptidylprolyl isomerase F
chr1_-_32403903 0.54 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr1_-_33502441 0.54 ENST00000548033.1
ENST00000487289.1
ENST00000373449.2
ENST00000480134.1
ENST00000467905.1
AK2
adenylate kinase 2
chr17_-_42144949 0.52 ENST00000591247.1
LSM12
LSM12 homolog (S. cerevisiae)
chr12_-_96793142 0.52 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr7_+_112063192 0.52 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr7_-_45151272 0.52 ENST00000461363.1
ENST00000495078.1
ENST00000494076.1
ENST00000478532.1
ENST00000258770.3
ENST00000361278.3
TBRG4
transforming growth factor beta regulator 4
chr10_-_94003003 0.52 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_+_165600436 0.51 ENST00000367888.4
ENST00000367885.1
ENST00000367884.2
MGST3
microsomal glutathione S-transferase 3
chr6_-_107077347 0.51 ENST00000369063.3
ENST00000539449.1
RTN4IP1
reticulon 4 interacting protein 1
chr12_-_58135903 0.51 ENST00000257897.3
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_+_145317356 0.51 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr1_-_150207017 0.50 ENST00000369119.3
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_+_56414851 0.50 ENST00000547167.1
IKZF4
IKAROS family zinc finger 4 (Eos)
chr3_+_189349162 0.50 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr17_-_27503770 0.48 ENST00000533112.1
MYO18A
myosin XVIIIA
chr16_-_85617170 0.48 ENST00000602862.1
RP11-118F19.1
RP11-118F19.1
chr5_-_140027175 0.48 ENST00000512088.1
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr13_-_76111945 0.48 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr14_-_23755297 0.46 ENST00000357460.5
HOMEZ
homeobox and leucine zipper encoding
chr17_-_44270133 0.46 ENST00000262419.6
ENST00000393476.3
KANSL1
KAT8 regulatory NSL complex subunit 1
chr7_-_105319536 0.45 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr1_-_241799232 0.45 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chrX_+_10124977 0.45 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr10_+_94050913 0.45 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chr9_-_86322831 0.45 ENST00000257468.7
UBQLN1
ubiquilin 1
chr14_-_23791484 0.45 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr14_-_58893876 0.44 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr3_-_49158218 0.44 ENST00000417901.1
ENST00000306026.5
ENST00000434032.2
USP19
ubiquitin specific peptidase 19
chr3_-_27498235 0.44 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr2_+_162016804 0.44 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr19_-_49140692 0.43 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_-_64512273 0.43 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr8_-_144654918 0.43 ENST00000529971.1
MROH6
maestro heat-like repeat family member 6
chr2_-_209118974 0.42 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr1_+_43148059 0.42 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr20_+_19870167 0.41 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr7_-_123197733 0.41 ENST00000470123.1
ENST00000471770.1
NDUFA5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr5_+_132208014 0.41 ENST00000296877.2
LEAP2
liver expressed antimicrobial peptide 2
chr2_+_208414985 0.41 ENST00000414681.1
CREB1
cAMP responsive element binding protein 1
chr3_-_47932759 0.41 ENST00000441748.2
ENST00000335271.5
MAP4
microtubule-associated protein 4
chr17_-_4458616 0.41 ENST00000381556.2
MYBBP1A
MYB binding protein (P160) 1a
chr10_-_94050820 0.40 ENST00000265997.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr14_+_22955216 0.40 ENST00000390486.1
TRAJ52
T cell receptor alpha joining 52
chr20_+_18125727 0.40 ENST00000489634.2
CSRP2BP
CSRP2 binding protein
chr7_-_25164969 0.39 ENST00000305786.2
CYCS
cytochrome c, somatic
chr10_-_52645379 0.39 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr9_+_139717847 0.38 ENST00000436380.1
RABL6
RAB, member RAS oncogene family-like 6
chr15_-_52263937 0.38 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr1_-_33502528 0.37 ENST00000354858.6
AK2
adenylate kinase 2
chr5_-_137071689 0.37 ENST00000505853.1
KLHL3
kelch-like family member 3
chr2_+_162016916 0.37 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr3_+_141105235 0.37 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_+_162016827 0.36 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr14_-_58893832 0.35 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr5_+_133562095 0.35 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr3_-_113464906 0.35 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_140027357 0.34 ENST00000252102.4
NDUFA2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
chr7_-_43965937 0.34 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr5_-_137071756 0.33 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr10_+_99185917 0.33 ENST00000334828.5
PGAM1
phosphoglycerate mutase 1 (brain)
chr2_+_109237717 0.33 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr15_-_42565023 0.33 ENST00000566474.1
TMEM87A
transmembrane protein 87A
chr2_+_134877740 0.33 ENST00000409645.1
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr3_-_49377446 0.32 ENST00000351842.4
ENST00000416417.1
ENST00000415188.1
USP4
ubiquitin specific peptidase 4 (proto-oncogene)
chr12_+_65672702 0.32 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr3_-_42845922 0.32 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr17_-_33390667 0.32 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr17_-_2615031 0.31 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr1_+_229440129 0.31 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr6_-_41039567 0.31 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr16_+_1832902 0.30 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr16_-_30457048 0.30 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr21_-_43816052 0.30 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr12_-_57039739 0.29 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr1_+_32666188 0.29 ENST00000421922.2
CCDC28B
coiled-coil domain containing 28B
chr3_-_69370095 0.28 ENST00000473029.1
FRMD4B
FERM domain containing 4B
chr17_-_48785216 0.28 ENST00000285243.6
ANKRD40
ankyrin repeat domain 40
chr3_+_50316458 0.28 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr17_+_2699697 0.27 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr6_-_111927062 0.26 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr7_+_129007964 0.26 ENST00000460109.1
ENST00000474594.1
ENST00000446212.1
AHCYL2
adenosylhomocysteinase-like 2
chr20_+_49126881 0.26 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr11_+_82868030 0.26 ENST00000298281.4
ENST00000530660.1
PCF11
PCF11 cleavage and polyadenylation factor subunit
chr6_-_89673280 0.26 ENST00000369475.3
ENST00000369485.4
ENST00000538899.1
ENST00000265607.6
RNGTT
RNA guanylyltransferase and 5'-phosphatase
chr11_+_82868185 0.26 ENST00000530304.1
ENST00000533018.1
PCF11
PCF11 cleavage and polyadenylation factor subunit
chr2_-_207024233 0.25 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr1_-_157108130 0.25 ENST00000368192.4
ETV3
ets variant 3
chr11_-_111957451 0.25 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr11_+_64879317 0.24 ENST00000526809.1
ENST00000279263.7
ENST00000524986.1
ENST00000534371.1
ENST00000540748.1
ENST00000525385.1
ENST00000345348.5
ENST00000531321.1
ENST00000529414.1
ENST00000526085.1
ENST00000530750.1
TM7SF2
transmembrane 7 superfamily member 2
chr16_+_82090028 0.23 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr12_-_122240792 0.23 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr19_-_11688951 0.23 ENST00000589792.1
ACP5
acid phosphatase 5, tartrate resistant

Network of associatons between targets according to the STRING database.

First level regulatory network of RORA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.5 1.4 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.4 1.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.4 1.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.3 1.0 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.3 1.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 2.0 GO:1904044 response to aldosterone(GO:1904044)
0.2 1.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.2 0.5 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.2 0.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.2 2.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 1.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 1.2 GO:0007296 vitellogenesis(GO:0007296)
0.1 2.0 GO:0007144 female meiosis I(GO:0007144)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 1.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.9 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.5 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 1.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.7 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.8 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.7 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 2.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.4 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.2 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.6 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.6 GO:0006477 protein sulfation(GO:0006477)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.0 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.9 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 3.0 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 0.4 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.7 GO:0007340 acrosome reaction(GO:0007340)
0.0 3.2 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.8 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.6 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.1 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 2.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 1.0 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.8 GO:0043276 anoikis(GO:0043276)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.6 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.1 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.5 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 2.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.2 0.6 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 0.8 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 1.4 GO:1990635 proximal dendrite(GO:1990635)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 0.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.2 0.8 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.7 GO:0070470 plasma membrane respiratory chain complex I(GO:0045272) plasma membrane respiratory chain(GO:0070470)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 1.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.2 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 1.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 4.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 2.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 2.3 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 1.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 0.8 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 0.6 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 2.5 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.8 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.7 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 1.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 2.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.2 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 1.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.2 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.0 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 2.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.0 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.9 GO:0004568 chitinase activity(GO:0004568)
0.1 1.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 1.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0050815 phosphoserine binding(GO:0050815)
0.0 3.0 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.1 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 5.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 5.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 5.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.2 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis