Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for RREB1
Z-value: 1.97
Motif logo
Transcription factors associated with RREB1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RREB1 | hg19_v2_chr6_+_7107830_7107993 | 0.41 | 2.0e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_54447637 Show fit | 4.55 |
ENST00000609810.1
ENST00000430889.2 |
homeobox C4 Homeobox protein Hox-C4 |
|
| chr4_-_154710210 Show fit | 3.55 |
ENST00000274063.4
|
secreted frizzled-related protein 2 |
|
| chr11_+_1092184 Show fit | 3.52 |
ENST00000361558.6
|
mucin 2, oligomeric mucus/gel-forming |
|
| chr11_+_1093318 Show fit | 3.50 |
ENST00000333592.6
|
mucin 2, oligomeric mucus/gel-forming |
|
| chr12_+_54384370 Show fit | 3.35 |
ENST00000504315.1
|
homeobox C6 |
|
| chr7_-_19157248 Show fit | 3.31 |
ENST00000242261.5
|
twist family bHLH transcription factor 1 |
|
| chr19_+_35609380 Show fit | 3.29 |
ENST00000604621.1
|
FXYD domain containing ion transport regulator 3 |
|
| chr3_+_192958914 Show fit | 2.94 |
ENST00000264735.2
ENST00000602513.1 |
HRAS-like suppressor |
|
| chrX_-_119249819 Show fit | 2.84 |
ENST00000217999.2
|
Rhox homeobox family, member 1 |
|
| chr12_-_53074182 Show fit | 2.78 |
ENST00000252244.3
|
keratin 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RREB1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.7 | GO:0009952 | anterior/posterior pattern specification(GO:0009952) |
| 0.9 | 9.5 | GO:0002775 | antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) |
| 0.0 | 5.2 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 1.5 | 4.5 | GO:0031448 | regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) |
| 0.3 | 4.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.4 | 4.3 | GO:0002414 | immunoglobulin transcytosis in epithelial cells(GO:0002414) |
| 0.1 | 4.2 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.8 | 4.0 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 1.2 | 3.6 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.2 | 3.4 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 7.0 | GO:0070702 | inner mucus layer(GO:0070702) outer mucus layer(GO:0070703) |
| 0.7 | 4.9 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.0 | 4.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 4.7 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.2 | 4.5 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 4.5 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 3.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 3.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 2.8 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.2 | 2.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 5.7 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.0 | 4.7 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 4.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.4 | 4.4 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.8 | 4.0 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.1 | 3.8 | GO:0043236 | laminin binding(GO:0043236) |
| 0.4 | 3.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 3.3 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 3.3 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.5 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 6.0 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 5.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 4.7 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 4.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 3.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.0 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 2.0 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.9 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 1.7 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.9 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.2 | 7.0 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 4.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.2 | 4.4 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 4.0 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 3.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 2.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 2.4 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 2.2 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.0 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |