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Illumina Body Map 2: averaged replicates

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Results for RUNX3_BCL11A

Z-value: 4.42

Motif logo

Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
ENSG00000020633.14 RUNX3
ENSG00000119866.16 BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX3hg19_v2_chr1_-_25291475_252915110.915.9e-13Click!
BCL11Ahg19_v2_chr2_-_60780607_607806340.441.3e-02Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_40297079 23.84 ENST00000344138.4
ENST00000543252.1
GRAP2
GRB2-related adaptor protein 2
chr3_-_150920979 23.08 ENST00000309180.5
ENST00000480322.1
GPR171
G protein-coupled receptor 171
chr6_+_45296048 19.97 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr1_-_114414316 19.04 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr5_+_156607829 18.76 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr22_+_40297105 18.08 ENST00000540310.1
GRAP2
GRB2-related adaptor protein 2
chr2_-_158300556 17.25 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chr1_-_25291475 16.38 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr4_+_71091786 15.38 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr2_+_7865923 14.98 ENST00000417930.1
AC092580.4
AC092580.4
chr5_+_35856951 14.87 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr11_+_60739115 14.58 ENST00000344028.5
ENST00000346437.4
CD6
CD6 molecule
chr5_+_54398463 14.33 ENST00000274306.6
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr12_-_68553512 14.07 ENST00000229135.3
IFNG
interferon, gamma
chr11_+_60739140 13.87 ENST00000313421.7
CD6
CD6 molecule
chr11_+_60739249 13.83 ENST00000542157.1
ENST00000433107.2
ENST00000452451.2
ENST00000352009.5
CD6
CD6 molecule
chr17_+_7239821 12.97 ENST00000158762.3
ENST00000570457.2
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr14_-_25103472 12.74 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_-_42636617 12.66 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2
POU class 2 homeobox 2
chr5_+_133451254 12.48 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr1_-_168513229 11.91 ENST00000367819.2
XCL2
chemokine (C motif) ligand 2
chr14_-_25103388 11.44 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr17_+_7239904 11.07 ENST00000575425.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chrX_+_37639302 10.80 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr19_-_42636543 10.48 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2
POU class 2 homeobox 2
chrX_+_48542168 10.17 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr13_-_99910673 10.05 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chrX_-_49121165 9.95 ENST00000376207.4
ENST00000376199.2
FOXP3
forkhead box P3
chr3_+_114012819 9.79 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr1_+_168545711 9.48 ENST00000367818.3
XCL1
chemokine (C motif) ligand 1
chr12_-_54694807 9.46 ENST00000435572.2
NFE2
nuclear factor, erythroid 2
chr12_-_53594227 9.37 ENST00000550743.2
ITGB7
integrin, beta 7
chrX_-_70838306 9.10 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chrX_+_37639264 9.01 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr3_+_98250743 8.92 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr6_+_27925019 8.91 ENST00000244623.1
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr1_+_209929377 8.88 ENST00000400959.3
ENST00000367025.3
TRAF3IP3
TRAF3 interacting protein 3
chr12_-_54694758 8.85 ENST00000553070.1
NFE2
nuclear factor, erythroid 2
chr12_-_10542617 8.77 ENST00000240618.6
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr1_+_209929494 8.71 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr14_+_22337014 8.50 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr1_-_92951607 8.43 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr4_-_48116540 7.90 ENST00000506073.1
TXK
TXK tyrosine kinase
chr22_+_23222886 7.81 ENST00000390319.2
IGLV3-1
immunoglobulin lambda variable 3-1
chr13_-_99910620 7.77 ENST00000416594.1
GPR18
G protein-coupled receptor 18
chr1_+_209929446 7.69 ENST00000479796.1
TRAF3IP3
TRAF3 interacting protein 3
chr2_+_90077680 7.32 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr4_-_109087906 7.30 ENST00000515500.1
LEF1
lymphoid enhancer-binding factor 1
chr17_-_34417479 7.27 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr19_-_8567505 7.22 ENST00000600262.1
PRAM1
PML-RARA regulated adaptor molecule 1
chr9_+_75766763 7.19 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr6_+_45296391 7.15 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr20_+_44637526 7.14 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr19_-_50868882 6.98 ENST00000598915.1
NAPSA
napsin A aspartic peptidase
chr10_+_17272608 6.92 ENST00000421459.2
VIM
vimentin
chr17_+_45810594 6.77 ENST00000177694.1
TBX21
T-box 21
chr14_+_22236722 6.72 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6
chr7_+_18535321 6.67 ENST00000413380.1
ENST00000430454.1
HDAC9
histone deacetylase 9
chr11_-_128457446 6.67 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr4_-_109087872 6.58 ENST00000510624.1
LEF1
lymphoid enhancer-binding factor 1
chr8_-_21771182 6.55 ENST00000523932.1
ENST00000544659.1
DOK2
docking protein 2, 56kDa
chr19_-_14785622 6.55 ENST00000443157.2
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr19_-_14785698 6.52 ENST00000344373.4
ENST00000595472.1
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr7_+_18535346 6.50 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
HDAC9
histone deacetylase 9
chr9_+_75766652 6.41 ENST00000257497.6
ANXA1
annexin A1
chrX_-_19688475 6.38 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_29648761 6.36 ENST00000247270.3
ENST00000462804.2
EVI2A
ecotropic viral integration site 2A
chr1_+_53098862 6.31 ENST00000517870.1
FAM159A
family with sequence similarity 159, member A
chr1_+_221051699 6.29 ENST00000366903.6
HLX
H2.0-like homeobox
chr17_-_61776522 6.25 ENST00000582055.1
LIMD2
LIM domain containing 2
chr6_+_15401075 6.25 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr19_-_14785674 6.23 ENST00000253673.5
EMR3
egf-like module containing, mucin-like, hormone receptor-like 3
chr17_-_61777090 6.22 ENST00000578061.1
LIMD2
LIM domain containing 2
chr11_-_2323290 6.22 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr1_+_32716840 6.13 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_32716857 6.09 ENST00000482949.1
ENST00000495610.2
LCK
lymphocyte-specific protein tyrosine kinase
chr8_-_21771214 6.05 ENST00000276420.4
DOK2
docking protein 2, 56kDa
chr14_+_22465771 6.04 ENST00000390445.2
TRAV17
T cell receptor alpha variable 17
chr12_-_51717875 6.02 ENST00000604560.1
BIN2
bridging integrator 2
chr3_-_72150076 5.98 ENST00000488545.1
ENST00000608654.1
LINC00877
long intergenic non-protein coding RNA 877
chr19_-_8567478 5.88 ENST00000255612.3
PRAM1
PML-RARA regulated adaptor molecule 1
chr8_+_22019168 5.88 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr12_-_51717948 5.88 ENST00000267012.4
BIN2
bridging integrator 2
chr17_-_56494713 5.87 ENST00000407977.2
RNF43
ring finger protein 43
chr8_-_21771173 5.77 ENST00000518197.1
DOK2
docking protein 2, 56kDa
chr12_-_51717922 5.76 ENST00000452142.2
BIN2
bridging integrator 2
chr16_+_31366455 5.76 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr4_-_84035868 5.73 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr4_-_109087445 5.73 ENST00000512172.1
LEF1
lymphoid enhancer-binding factor 1
chr1_+_159770292 5.69 ENST00000536257.1
ENST00000321935.6
FCRL6
Fc receptor-like 6
chr4_-_71532601 5.66 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_+_86098670 5.66 ENST00000558811.1
AKAP13
A kinase (PRKA) anchor protein 13
chr19_-_51875894 5.63 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr1_+_198608146 5.60 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_-_71532668 5.49 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr7_-_142176790 5.47 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr1_-_157522260 5.41 ENST00000368191.3
ENST00000361835.3
FCRL5
Fc receptor-like 5
chr4_-_71532207 5.33 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_-_39270725 5.30 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr1_+_198608292 5.26 ENST00000418674.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_109025849 5.22 ENST00000228463.6
SELPLG
selectin P ligand
chr11_+_2323236 5.20 ENST00000182290.4
TSPAN32
tetraspanin 32
chr1_-_157522180 5.20 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5
Fc receptor-like 5
chr4_-_84035905 5.17 ENST00000311507.4
PLAC8
placenta-specific 8
chr15_+_58430368 5.15 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr4_-_71532339 5.15 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_-_36233332 5.12 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr1_+_172628154 5.12 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr11_+_2323349 5.06 ENST00000381121.3
TSPAN32
tetraspanin 32
chr3_+_111260980 5.00 ENST00000438817.2
CD96
CD96 molecule
chr17_-_47287928 4.92 ENST00000507680.1
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr3_+_113251143 4.76 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr3_+_111260954 4.74 ENST00000283285.5
CD96
CD96 molecule
chr3_+_111260856 4.74 ENST00000352690.4
CD96
CD96 molecule
chr17_-_73840614 4.68 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr17_-_73840415 4.64 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chr2_+_103035102 4.62 ENST00000264260.2
IL18RAP
interleukin 18 receptor accessory protein
chr11_+_35198243 4.61 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr1_-_207095212 4.60 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr17_-_46262541 4.60 ENST00000579336.1
SKAP1
src kinase associated phosphoprotein 1
chr1_+_17634689 4.60 ENST00000375453.1
ENST00000375448.4
PADI4
peptidyl arginine deiminase, type IV
chr14_+_22508822 4.59 ENST00000390448.3
TRAV20
T cell receptor alpha variable 20
chr15_+_58430567 4.58 ENST00000536493.1
AQP9
aquaporin 9
chr3_-_151047327 4.52 ENST00000325602.5
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr17_+_38673270 4.51 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr11_-_118122996 4.51 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr11_-_2323089 4.47 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr11_-_58345569 4.45 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr1_+_26872324 4.42 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_35198118 4.39 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr10_+_17270214 4.33 ENST00000544301.1
VIM
vimentin
chr19_+_7413835 4.31 ENST00000576789.1
CTB-133G6.1
CTB-133G6.1
chr12_-_53012343 4.28 ENST00000305748.3
KRT73
keratin 73
chr6_+_31543334 4.24 ENST00000449264.2
TNF
tumor necrosis factor
chr6_+_144904334 4.21 ENST00000367526.4
UTRN
utrophin
chr5_-_94417562 4.20 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_138861926 4.16 ENST00000510817.1
TMEM173
transmembrane protein 173
chr19_-_44285401 4.14 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr13_-_46756351 4.12 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_30029008 4.06 ENST00000332435.5
ENST00000376782.2
ENST00000359374.4
ENST00000376785.2
ZNRD1
zinc ribbon domain containing 1
chr8_+_24241789 4.05 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr1_-_153517473 4.04 ENST00000368715.1
S100A4
S100 calcium binding protein A4
chr1_-_153348067 4.02 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr16_+_85942594 4.01 ENST00000566369.1
IRF8
interferon regulatory factor 8
chr3_-_112218378 4.01 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr1_+_158223923 3.96 ENST00000289429.5
CD1A
CD1a molecule
chr5_-_39203093 3.94 ENST00000515010.1
FYB
FYN binding protein
chr1_-_207095324 3.94 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr8_-_60031762 3.93 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr7_+_18330035 3.92 ENST00000413509.2
HDAC9
histone deacetylase 9
chr3_-_112218205 3.84 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr14_+_22573582 3.83 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr11_+_1892102 3.81 ENST00000417766.1
LSP1
lymphocyte-specific protein 1
chr20_+_54987168 3.81 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr1_+_113161778 3.76 ENST00000263168.3
CAPZA1
capping protein (actin filament) muscle Z-line, alpha 1
chr1_-_161039456 3.74 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr14_+_75988768 3.70 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr2_-_175462456 3.69 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_42418999 3.67 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr17_-_34524157 3.58 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr17_-_34625719 3.53 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr7_-_115670792 3.53 ENST00000265440.7
ENST00000393485.1
TFEC
transcription factor EC
chr14_+_75988851 3.51 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr3_-_72149553 3.51 ENST00000468646.2
ENST00000464271.1
LINC00877
long intergenic non-protein coding RNA 877
chr5_-_94417314 3.48 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_134072593 3.45 ENST00000427060.2
SLA
Src-like-adaptor
chr15_-_55563072 3.38 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr9_-_130541017 3.35 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr2_+_30455016 3.33 ENST00000401506.1
ENST00000407930.2
LBH
limb bud and heart development
chr17_+_47287749 3.32 ENST00000419580.2
ABI3
ABI family, member 3
chr1_-_145715565 3.28 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr5_-_94417186 3.28 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr20_+_36932521 3.27 ENST00000262865.4
BPI
bactericidal/permeability-increasing protein
chr22_-_30642728 3.27 ENST00000403987.3
LIF
leukemia inhibitory factor
chr2_-_175462934 3.19 ENST00000392546.2
ENST00000436221.1
WIPF1
WAS/WASL interacting protein family, member 1
chr7_-_115670804 3.17 ENST00000320239.7
TFEC
transcription factor EC
chr8_+_24241969 3.15 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr1_-_235098935 3.15 ENST00000423175.1
RP11-443B7.1
RP11-443B7.1
chr1_+_117544366 3.15 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr15_-_60695071 3.12 ENST00000557904.1
ANXA2
annexin A2
chr8_-_101718991 3.11 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr17_-_1532106 3.11 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr5_+_148206156 3.08 ENST00000305988.4
ADRB2
adrenoceptor beta 2, surface
chr20_+_54987305 3.04 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr4_-_54930790 3.01 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr1_-_206945830 3.00 ENST00000423557.1
IL10
interleukin 10
chr12_+_54410664 2.99 ENST00000303406.4
HOXC4
homeobox C4
chr1_-_161039753 2.99 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chrX_+_155227246 2.93 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr5_-_94417339 2.92 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr11_+_36397528 2.91 ENST00000311599.5
ENST00000378867.3
PRR5L
proline rich 5 like
chr8_-_101719159 2.85 ENST00000520868.1
ENST00000522658.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_103889731 2.81 ENST00000552578.1
ENST00000548048.1
ENST00000315192.8
ENST00000548883.1
ENST00000378113.2
C12orf42
chromosome 12 open reading frame 42
chr15_+_49715293 2.78 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr13_-_28674693 2.77 ENST00000537084.1
ENST00000241453.7
ENST00000380982.4
FLT3
fms-related tyrosine kinase 3
chr1_+_111772375 2.76 ENST00000467038.2
ENST00000497587.2
CHI3L2
chitinase 3-like 2
chrX_+_47441712 2.71 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr19_+_10947251 2.70 ENST00000592854.1
C19orf38
chromosome 19 open reading frame 38
chr15_-_55562479 2.68 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chrX_+_155227371 2.66 ENST00000369423.2
ENST00000540897.1
IL9R
interleukin 9 receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 24.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
4.8 14.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
4.8 19.0 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
4.5 13.6 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
4.5 17.8 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
4.0 19.8 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
3.2 9.5 GO:2000562 positive regulation of thymocyte migration(GO:2000412) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
3.0 24.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.9 8.8 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
2.8 8.4 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
2.8 19.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
2.7 13.3 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
2.5 10.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
2.4 4.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
2.3 9.3 GO:0002432 granuloma formation(GO:0002432)
2.2 10.9 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
2.1 40.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
2.1 4.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
2.1 27.3 GO:0002051 osteoblast fate commitment(GO:0002051)
1.9 9.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.8 12.5 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
1.6 9.7 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
1.6 11.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
1.4 4.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.3 6.7 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
1.3 5.2 GO:0050902 leukocyte adhesive activation(GO:0050902)
1.2 14.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
1.2 7.3 GO:2000503 regulation of natural killer cell chemotaxis(GO:2000501) positive regulation of natural killer cell chemotaxis(GO:2000503)
1.2 4.7 GO:2001301 cellular response to interleukin-13(GO:0035963) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
1.2 4.7 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
1.1 7.9 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
1.1 9.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.1 18.8 GO:0001865 NK T cell differentiation(GO:0001865)
1.0 3.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
1.0 14.3 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
1.0 7.1 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
1.0 28.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
1.0 13.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
1.0 7.0 GO:0043129 surfactant homeostasis(GO:0043129)
1.0 21.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.0 4.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.9 5.7 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.9 5.5 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.9 4.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.9 6.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.9 2.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.9 5.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) endosomal lumen acidification(GO:0048388)
0.8 24.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.8 11.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.8 3.1 GO:0052214 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.8 16.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.8 0.8 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.7 2.9 GO:0002884 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.7 3.5 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.7 5.6 GO:0071104 response to interleukin-9(GO:0071104)
0.7 2.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.6 1.9 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.6 1.9 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.6 2.5 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.6 2.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6 1.7 GO:0070376 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.5 10.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.5 18.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.5 3.5 GO:0071461 cellular response to redox state(GO:0071461)
0.5 5.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.5 6.0 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 4.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.5 3.4 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.5 6.8 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.5 24.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.5 11.2 GO:0042832 defense response to protozoan(GO:0042832)
0.4 6.7 GO:0033227 dsRNA transport(GO:0033227)
0.4 8.9 GO:0072678 T cell migration(GO:0072678)
0.4 4.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 51.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.4 7.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.4 9.8 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.4 3.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.4 1.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 1.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.4 2.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.4 4.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4 2.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.4 20.9 GO:0071800 podosome assembly(GO:0071800)
0.4 1.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.4 6.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 5.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.4 2.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.4 1.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4 1.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.3 1.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3 1.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.3 1.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 4.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 2.9 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 1.1 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.3 0.8 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 0.8 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
0.2 1.0 GO:0060558 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) regulation of calcidiol 1-monooxygenase activity(GO:0060558) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.2 0.7 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 4.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.2 1.2 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.2 4.3 GO:0038203 TORC2 signaling(GO:0038203)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 4.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 1.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 10.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 0.4 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.2 1.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.2 5.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 1.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.2 3.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.2 3.0 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.2 0.5 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 1.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.5 GO:0043132 NAD transport(GO:0043132)
0.1 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 4.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 24.6 GO:0038096 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.1 1.3 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.9 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 2.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.3 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.1 8.6 GO:0031295 T cell costimulation(GO:0031295)
0.1 2.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.1 2.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.3 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.1 3.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 3.8 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 1.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 2.3 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.1 3.1 GO:0016180 snRNA processing(GO:0016180)
0.1 0.5 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 1.6 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 7.7 GO:0006968 cellular defense response(GO:0006968)
0.1 5.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 4.0 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.5 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 4.7 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.9 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 6.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.1 4.8 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.5 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.3 GO:0090166 Golgi disassembly(GO:0090166)
0.1 5.8 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.1 1.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.5 GO:0043144 snoRNA processing(GO:0043144)
0.1 0.7 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.7 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.1 1.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.5 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 1.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 4.9 GO:0007602 phototransduction(GO:0007602)
0.0 0.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 8.9 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 4.7 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.8 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 2.1 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.1 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 7.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.8 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.7 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.6 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 16.4 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 18.3 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.6 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 3.0 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.7 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 1.3 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 1.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 3.3 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.4 GO:0051131 trophectodermal cell differentiation(GO:0001829) chaperone-mediated protein complex assembly(GO:0051131)
0.0 4.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.6 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.9 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 1.1 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 1.9 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 1.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.2 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 2.1 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.5 13.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.4 19.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.2 93.5 GO:0001772 immunological synapse(GO:0001772)
1.1 9.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.1 12.7 GO:0097486 multivesicular body lumen(GO:0097486)
1.0 19.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 19.8 GO:0043020 NADPH oxidase complex(GO:0043020)
0.9 26.0 GO:0001891 phagocytic cup(GO:0001891)
0.8 3.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.7 3.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.5 3.8 GO:0071203 WASH complex(GO:0071203)
0.5 2.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.5 6.8 GO:0043025 neuronal cell body(GO:0043025)
0.4 89.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 6.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.3 0.8 GO:0018444 translation release factor complex(GO:0018444)
0.3 5.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 11.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.2 23.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 12.1 GO:0008305 integrin complex(GO:0008305)
0.2 4.2 GO:0070938 contractile ring(GO:0070938)
0.2 30.8 GO:0035097 histone methyltransferase complex(GO:0035097)
0.2 5.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 5.7 GO:0031932 TORC2 complex(GO:0031932)
0.2 4.6 GO:0042101 T cell receptor complex(GO:0042101)
0.2 4.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 62.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 4.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 3.9 GO:0010369 chromocenter(GO:0010369)
0.1 4.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 10.9 GO:0043235 receptor complex(GO:0043235)
0.1 20.4 GO:0016605 PML body(GO:0016605)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.8 GO:0032039 integrator complex(GO:0032039)
0.1 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 14.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 10.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 5.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 18.9 GO:0005884 actin filament(GO:0005884)
0.1 10.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.0 GO:0072487 MSL complex(GO:0072487)
0.1 43.2 GO:0000790 nuclear chromatin(GO:0000790)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 1.0 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 8.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.7 GO:0031519 PcG protein complex(GO:0031519)
0.1 3.5 GO:1990391 DNA repair complex(GO:1990391)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.5 GO:0055028 cortical microtubule(GO:0055028)
0.1 1.2 GO:0012505 endomembrane system(GO:0012505)
0.0 5.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 2.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.1 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.7 GO:0031105 septin complex(GO:0031105)
0.0 19.5 GO:0005769 early endosome(GO:0005769)
0.0 9.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 22.1 GO:0005912 adherens junction(GO:0005912)
0.0 2.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.9 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.7 GO:0097223 acrosomal vesicle(GO:0001669) sperm part(GO:0097223)
0.0 1.5 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.9 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 42.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
3.7 14.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
1.9 9.7 GO:0015254 glycerol channel activity(GO:0015254)
1.6 14.6 GO:0042610 CD8 receptor binding(GO:0042610)
1.6 11.3 GO:1990254 keratin filament binding(GO:1990254)
1.6 4.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.5 16.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.2 7.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
1.2 4.7 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
1.1 6.7 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
1.0 19.6 GO:0030284 estrogen receptor activity(GO:0030284)
1.0 3.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
1.0 28.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.9 5.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.9 4.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.9 2.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.8 19.8 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 9.9 GO:0051525 NFAT protein binding(GO:0051525)
0.7 75.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.7 4.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.7 2.1 GO:0030395 lactose binding(GO:0030395)
0.7 4.1 GO:0050436 microfibril binding(GO:0050436)
0.7 2.0 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.6 1.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 21.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.6 24.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.6 17.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.6 9.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.5 5.5 GO:0036310 annealing helicase activity(GO:0036310)
0.4 7.8 GO:0004568 chitinase activity(GO:0004568)
0.4 1.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 4.0 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.4 1.2 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.4 3.5 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.4 3.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 27.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.4 1.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.4 5.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.4 8.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.3 3.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.3 10.2 GO:0043274 phospholipase binding(GO:0043274)
0.3 1.0 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 11.0 GO:0031489 myosin V binding(GO:0031489)
0.3 1.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 6.9 GO:0005522 profilin binding(GO:0005522)
0.3 3.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.3 14.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.3 2.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.3 3.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.2 1.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.2 5.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 8.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 6.0 GO:0008494 translation activator activity(GO:0008494)
0.2 1.5 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.2 9.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 4.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 6.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 10.8 GO:0032452 histone demethylase activity(GO:0032452)
0.2 1.2 GO:0045569 TRAIL binding(GO:0045569)
0.2 12.0 GO:0050699 WW domain binding(GO:0050699)
0.2 4.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.7 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.2 2.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.2 3.7 GO:0008301 DNA binding, bending(GO:0008301)
0.2 2.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.2 8.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 1.4 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 6.0 GO:0017166 vinculin binding(GO:0017166)
0.1 2.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 2.3 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 0.4 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 4.9 GO:0042056 chemoattractant activity(GO:0042056)
0.1 15.2 GO:0001618 virus receptor activity(GO:0001618)
0.1 5.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 44.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 3.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 3.0 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.3 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 12.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 3.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 13.4 GO:0008013 beta-catenin binding(GO:0008013)
0.1 4.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 4.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 4.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 1.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 9.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 37.1 GO:0005096 GTPase activator activity(GO:0005096)
0.1 15.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 8.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.4 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.2 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 4.4 GO:0050681 androgen receptor binding(GO:0050681)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 1.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 13.4 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.5 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0 1.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 14.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 3.8 GO:0008289 lipid binding(GO:0008289)
0.0 1.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 4.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.9 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 9.3 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 6.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 2.0 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 5.8 GO:0003682 chromatin binding(GO:0003682)
0.0 1.1 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 2.4 GO:0051020 GTPase binding(GO:0051020)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.0 GO:0047485 protein N-terminus binding(GO:0047485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 41.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.9 14.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.7 29.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6 7.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 23.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.5 64.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.5 9.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.5 5.2 PID IL27 PATHWAY IL27-mediated signaling events
0.5 15.1 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.4 29.0 PID BCR 5PATHWAY BCR signaling pathway
0.4 39.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 27.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.3 10.8 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.3 29.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.2 9.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 32.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 19.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 22.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 8.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 5.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 7.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 9.7 PID AURORA B PATHWAY Aurora B signaling
0.1 3.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 5.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.1 1.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 29.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 6.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 3.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 5.5 PID ATR PATHWAY ATR signaling pathway
0.1 5.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 2.9 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 7.4 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.1 2.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 24.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 5.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 3.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 6.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 92.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
1.4 10.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6 9.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.6 46.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 18.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.5 14.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.5 27.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4 14.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.4 9.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 5.6 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.4 10.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.4 23.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.3 35.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 11.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.3 11.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 7.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 13.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 7.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 21.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2 5.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 5.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 32.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.2 3.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 6.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 21.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 7.4 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 7.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.1 6.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.1 1.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 18.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 7.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 18.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 4.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 3.0 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 2.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 2.9 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 1.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 2.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules