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Illumina Body Map 2: averaged replicates
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Results for RXRA_NR2F6_NR2C2
Z-value: 1.97
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Transcription factors associated with RXRA_NR2F6_NR2C2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RXRA
|
ENSG00000186350.8 | retinoid X receptor alpha |
|
NR2F6
|
ENSG00000160113.5 | nuclear receptor subfamily 2 group F member 6 |
|
NR2C2
|
ENSG00000177463.11 | nuclear receptor subfamily 2 group C member 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR2C2 | hg19_v2_chr3_+_14989076_14989113 | -0.71 | 4.8e-06 | Click! |
| RXRA | hg19_v2_chr9_+_137218362_137218426 | 0.41 | 1.9e-02 | Click! |
| NR2F6 | hg19_v2_chr19_-_17356697_17356762 | 0.40 | 2.4e-02 | Click! |
Activity profile of RXRA_NR2F6_NR2C2 motif
Sorted Z-values of RXRA_NR2F6_NR2C2 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_4153598 | 5.50 |
ENST00000078445.2
ENST00000252587.3 ENST00000595923.1 ENST00000602257.1 ENST00000602147.1 |
CREB3L3
|
cAMP responsive element binding protein 3-like 3 |
| chr1_-_161193349 | 5.38 |
ENST00000469730.2
ENST00000463273.1 ENST00000464492.1 ENST00000367990.3 ENST00000470459.2 ENST00000468465.1 ENST00000463812.1 |
APOA2
|
apolipoprotein A-II |
| chr17_-_34329084 | 4.99 |
ENST00000354059.4
ENST00000536149.1 |
CCL15
CCL14
|
chemokine (C-C motif) ligand 15 chemokine (C-C motif) ligand 14 |
| chr3_+_46538981 | 4.46 |
ENST00000296142.3
|
RTP3
|
receptor (chemosensory) transporter protein 3 |
| chrX_+_138612889 | 4.28 |
ENST00000218099.2
ENST00000394090.2 |
F9
|
coagulation factor IX |
| chr11_-_116694009 | 4.28 |
ENST00000357780.3
|
APOA4
|
apolipoprotein A-IV |
| chr10_-_74714533 | 3.93 |
ENST00000373032.3
|
PLA2G12B
|
phospholipase A2, group XIIB |
| chr17_+_1646130 | 3.92 |
ENST00000453066.1
ENST00000324015.3 ENST00000450523.2 ENST00000453723.1 ENST00000382061.4 |
SERPINF2
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| chr12_-_21757774 | 3.90 |
ENST00000261195.2
|
GYS2
|
glycogen synthase 2 (liver) |
| chr1_-_173886491 | 3.73 |
ENST00000367698.3
|
SERPINC1
|
serpin peptidase inhibitor, clade C (antithrombin), member 1 |
| chr10_-_96829246 | 3.63 |
ENST00000371270.3
ENST00000535898.1 ENST00000539050.1 |
CYP2C8
|
cytochrome P450, family 2, subfamily C, polypeptide 8 |
| chrX_-_55020511 | 3.63 |
ENST00000375006.3
ENST00000374992.2 |
PFKFB1
|
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| chr4_+_159593418 | 3.62 |
ENST00000507475.1
ENST00000307738.5 |
ETFDH
|
electron-transferring-flavoprotein dehydrogenase |
| chrX_+_128872998 | 3.19 |
ENST00000371106.3
|
XPNPEP2
|
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| chr18_-_47340297 | 3.08 |
ENST00000586485.1
ENST00000587994.1 ENST00000586100.1 ENST00000285093.10 |
ACAA2
|
acetyl-CoA acyltransferase 2 |
| chr1_-_11107280 | 3.06 |
ENST00000400897.3
ENST00000400898.3 |
MASP2
|
mannan-binding lectin serine peptidase 2 |
| chr1_-_169555779 | 3.01 |
ENST00000367797.3
ENST00000367796.3 |
F5
|
coagulation factor V (proaccelerin, labile factor) |
| chr20_+_56136136 | 3.00 |
ENST00000319441.4
ENST00000543666.1 |
PCK1
|
phosphoenolpyruvate carboxykinase 1 (soluble) |
| chr11_+_116700600 | 2.90 |
ENST00000227667.3
|
APOC3
|
apolipoprotein C-III |
| chr19_-_17356697 | 2.86 |
ENST00000291442.3
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6 |
| chr1_+_65613340 | 2.86 |
ENST00000546702.1
|
AK4
|
adenylate kinase 4 |
| chr17_+_27369918 | 2.83 |
ENST00000323372.4
|
PIPOX
|
pipecolic acid oxidase |
| chr11_+_116700614 | 2.83 |
ENST00000375345.1
|
APOC3
|
apolipoprotein C-III |
| chr12_-_7125770 | 2.82 |
ENST00000261407.4
|
LPCAT3
|
lysophosphatidylcholine acyltransferase 3 |
| chrX_+_128872918 | 2.77 |
ENST00000371105.3
|
XPNPEP2
|
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound |
| chr1_+_145727681 | 2.68 |
ENST00000417171.1
ENST00000451928.2 |
PDZK1
|
PDZ domain containing 1 |
| chr2_+_219283815 | 2.67 |
ENST00000248444.5
ENST00000454069.1 ENST00000392114.2 |
VIL1
|
villin 1 |
| chr17_+_7123207 | 2.64 |
ENST00000584103.1
ENST00000579886.2 |
ACADVL
|
acyl-CoA dehydrogenase, very long chain |
| chr17_+_4853442 | 2.64 |
ENST00000522301.1
|
ENO3
|
enolase 3 (beta, muscle) |
| chr17_-_34345002 | 2.62 |
ENST00000293280.2
|
CCL23
|
chemokine (C-C motif) ligand 23 |
| chr19_-_36304201 | 2.42 |
ENST00000301175.3
|
PRODH2
|
proline dehydrogenase (oxidase) 2 |
| chr17_-_34344991 | 2.40 |
ENST00000591423.1
|
CCL23
|
chemokine (C-C motif) ligand 23 |
| chr1_-_120311517 | 2.40 |
ENST00000369406.3
ENST00000544913.2 |
HMGCS2
|
3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) |
| chr1_-_169555709 | 2.33 |
ENST00000546081.1
|
F5
|
coagulation factor V (proaccelerin, labile factor) |
| chr19_-_48867291 | 2.33 |
ENST00000435956.3
|
TMEM143
|
transmembrane protein 143 |
| chr19_-_59023348 | 2.33 |
ENST00000601355.1
ENST00000263093.2 |
SLC27A5
|
solute carrier family 27 (fatty acid transporter), member 5 |
| chr17_+_7533439 | 2.30 |
ENST00000441599.2
ENST00000380450.4 ENST00000416273.3 ENST00000575903.1 ENST00000576830.1 ENST00000571153.1 ENST00000575618.1 ENST00000576152.1 |
SHBG
|
sex hormone-binding globulin |
| chr17_+_7123125 | 2.29 |
ENST00000356839.5
ENST00000583312.1 ENST00000350303.5 |
ACADVL
|
acyl-CoA dehydrogenase, very long chain |
| chr3_-_48936272 | 2.27 |
ENST00000544097.1
ENST00000430379.1 ENST00000319017.4 |
SLC25A20
|
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 |
| chrX_+_66764375 | 2.21 |
ENST00000374690.3
|
AR
|
androgen receptor |
| chr9_-_33402506 | 2.20 |
ENST00000377425.4
ENST00000537089.1 ENST00000297988.1 ENST00000539936.1 ENST00000541274.1 |
AQP7
|
aquaporin 7 |
| chr19_-_39303576 | 2.18 |
ENST00000594209.1
|
LGALS4
|
lectin, galactoside-binding, soluble, 4 |
| chr6_+_43265992 | 2.18 |
ENST00000449231.1
ENST00000372589.3 ENST00000372585.5 |
SLC22A7
|
solute carrier family 22 (organic anion transporter), member 7 |
| chr10_-_54531406 | 2.14 |
ENST00000373968.3
|
MBL2
|
mannose-binding lectin (protein C) 2, soluble |
| chr1_-_155270770 | 2.13 |
ENST00000392414.3
|
PKLR
|
pyruvate kinase, liver and RBC |
| chr6_+_33172407 | 2.10 |
ENST00000374662.3
|
HSD17B8
|
hydroxysteroid (17-beta) dehydrogenase 8 |
| chr8_-_17555164 | 2.09 |
ENST00000297488.6
|
MTUS1
|
microtubule associated tumor suppressor 1 |
| chr1_-_155271213 | 2.06 |
ENST00000342741.4
|
PKLR
|
pyruvate kinase, liver and RBC |
| chr19_-_48867171 | 2.06 |
ENST00000377431.2
ENST00000436660.2 ENST00000541566.1 |
TMEM143
|
transmembrane protein 143 |
| chr13_+_100741269 | 2.04 |
ENST00000376286.4
ENST00000376279.3 ENST00000376285.1 |
PCCA
|
propionyl CoA carboxylase, alpha polypeptide |
| chr17_-_79817091 | 1.98 |
ENST00000570907.1
|
P4HB
|
prolyl 4-hydroxylase, beta polypeptide |
| chr6_+_43266063 | 1.95 |
ENST00000372574.3
|
SLC22A7
|
solute carrier family 22 (organic anion transporter), member 7 |
| chr17_-_2614927 | 1.93 |
ENST00000435359.1
|
CLUH
|
clustered mitochondria (cluA/CLU1) homolog |
| chr11_-_116708302 | 1.87 |
ENST00000375320.1
ENST00000359492.2 ENST00000375329.2 ENST00000375323.1 |
APOA1
|
apolipoprotein A-I |
| chr1_+_61548225 | 1.86 |
ENST00000371187.3
|
NFIA
|
nuclear factor I/A |
| chr9_+_115142217 | 1.85 |
ENST00000398805.3
ENST00000398803.1 ENST00000262542.7 ENST00000539114.1 |
HSDL2
|
hydroxysteroid dehydrogenase like 2 |
| chr2_+_234621551 | 1.76 |
ENST00000608381.1
ENST00000373414.3 |
UGT1A1
UGT1A5
|
UDP glucuronosyltransferase 1 family, polypeptide A8 UDP glucuronosyltransferase 1 family, polypeptide A5 |
| chr17_-_2615031 | 1.75 |
ENST00000576885.1
ENST00000574426.2 |
CLUH
|
clustered mitochondria (cluA/CLU1) homolog |
| chr20_+_36661910 | 1.75 |
ENST00000373433.4
|
RPRD1B
|
regulation of nuclear pre-mRNA domain containing 1B |
| chr16_-_4401284 | 1.73 |
ENST00000318059.3
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| chr17_+_79761997 | 1.73 |
ENST00000400723.3
ENST00000570996.1 |
GCGR
|
glucagon receptor |
| chr7_-_75452673 | 1.70 |
ENST00000416943.1
|
CCL24
|
chemokine (C-C motif) ligand 24 |
| chr12_+_109577202 | 1.69 |
ENST00000377848.3
ENST00000377854.5 |
ACACB
|
acetyl-CoA carboxylase beta |
| chr4_+_159593271 | 1.69 |
ENST00000512251.1
ENST00000511912.1 |
ETFDH
|
electron-transferring-flavoprotein dehydrogenase |
| chr2_+_200820494 | 1.66 |
ENST00000435773.2
|
C2orf47
|
chromosome 2 open reading frame 47 |
| chr2_+_234627424 | 1.66 |
ENST00000373409.3
|
UGT1A4
|
UDP glucuronosyltransferase 1 family, polypeptide A4 |
| chr13_+_28527647 | 1.65 |
ENST00000567234.1
|
LINC00543
|
long intergenic non-protein coding RNA 543 |
| chr3_+_52812523 | 1.64 |
ENST00000540715.1
|
ITIH1
|
inter-alpha-trypsin inhibitor heavy chain 1 |
| chr7_+_97840739 | 1.61 |
ENST00000609256.1
|
BHLHA15
|
basic helix-loop-helix family, member a15 |
| chr12_+_132413739 | 1.58 |
ENST00000443358.2
|
PUS1
|
pseudouridylate synthase 1 |
| chr6_+_31895467 | 1.58 |
ENST00000556679.1
ENST00000456570.1 |
CFB
CFB
|
complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B |
| chr2_+_200820269 | 1.57 |
ENST00000392290.1
|
C2orf47
|
chromosome 2 open reading frame 47 |
| chr20_+_44509857 | 1.57 |
ENST00000372523.1
ENST00000372520.1 |
ZSWIM1
|
zinc finger, SWIM-type containing 1 |
| chr11_+_114128522 | 1.54 |
ENST00000535401.1
|
NNMT
|
nicotinamide N-methyltransferase |
| chr11_+_64073699 | 1.54 |
ENST00000405666.1
ENST00000468670.1 |
ESRRA
|
estrogen-related receptor alpha |
| chr20_+_42984330 | 1.52 |
ENST00000316673.4
ENST00000609795.1 ENST00000457232.1 ENST00000609262.1 |
HNF4A
|
hepatocyte nuclear factor 4, alpha |
| chr1_+_65613852 | 1.52 |
ENST00000327299.7
|
AK4
|
adenylate kinase 4 |
| chr3_+_186383741 | 1.51 |
ENST00000232003.4
|
HRG
|
histidine-rich glycoprotein |
| chr17_-_1613663 | 1.50 |
ENST00000330676.6
|
TLCD2
|
TLC domain containing 2 |
| chr10_+_96443378 | 1.49 |
ENST00000285979.6
|
CYP2C18
|
cytochrome P450, family 2, subfamily C, polypeptide 18 |
| chrX_+_38211777 | 1.48 |
ENST00000039007.4
|
OTC
|
ornithine carbamoyltransferase |
| chr6_+_131148538 | 1.48 |
ENST00000541421.2
|
SMLR1
|
small leucine-rich protein 1 |
| chr19_+_35773242 | 1.47 |
ENST00000222304.3
|
HAMP
|
hepcidin antimicrobial peptide |
| chr1_+_61547894 | 1.47 |
ENST00000403491.3
|
NFIA
|
nuclear factor I/A |
| chr1_+_65613513 | 1.46 |
ENST00000395334.2
|
AK4
|
adenylate kinase 4 |
| chr3_+_186330712 | 1.46 |
ENST00000411641.2
ENST00000273784.5 |
AHSG
|
alpha-2-HS-glycoprotein |
| chr19_-_6720686 | 1.45 |
ENST00000245907.6
|
C3
|
complement component 3 |
| chr5_-_42812143 | 1.43 |
ENST00000514985.1
|
SEPP1
|
selenoprotein P, plasma, 1 |
| chr6_+_31895287 | 1.43 |
ENST00000447952.2
|
C2
|
complement component 2 |
| chr12_+_56624436 | 1.41 |
ENST00000266980.4
ENST00000437277.1 |
SLC39A5
|
solute carrier family 39 (zinc transporter), member 5 |
| chr1_+_61548374 | 1.40 |
ENST00000485903.2
ENST00000371185.2 ENST00000371184.2 |
NFIA
|
nuclear factor I/A |
| chr17_+_7531281 | 1.40 |
ENST00000575729.1
ENST00000340624.5 |
SHBG
|
sex hormone-binding globulin |
| chr12_+_121163538 | 1.40 |
ENST00000242592.4
|
ACADS
|
acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| chr6_+_31895480 | 1.39 |
ENST00000418949.2
ENST00000383177.3 ENST00000477310.1 |
C2
CFB
|
complement component 2 Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B |
| chr6_+_31895254 | 1.39 |
ENST00000299367.5
ENST00000442278.2 |
C2
|
complement component 2 |
| chr6_+_31916733 | 1.38 |
ENST00000483004.1
|
CFB
|
complement factor B |
| chr19_+_44100632 | 1.37 |
ENST00000533118.1
|
ZNF576
|
zinc finger protein 576 |
| chr12_+_132413765 | 1.35 |
ENST00000376649.3
ENST00000322060.5 |
PUS1
|
pseudouridylate synthase 1 |
| chr7_-_65447192 | 1.34 |
ENST00000421103.1
ENST00000345660.6 ENST00000304895.4 |
GUSB
|
glucuronidase, beta |
| chr5_-_42811986 | 1.34 |
ENST00000511224.1
ENST00000507920.1 ENST00000510965.1 |
SEPP1
|
selenoprotein P, plasma, 1 |
| chr2_+_120125245 | 1.33 |
ENST00000393103.2
|
DBI
|
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| chr12_+_54694979 | 1.32 |
ENST00000552848.1
|
COPZ1
|
coatomer protein complex, subunit zeta 1 |
| chr17_+_1674982 | 1.31 |
ENST00000572048.1
ENST00000573763.1 |
SERPINF1
|
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| chr10_+_101542462 | 1.31 |
ENST00000370449.4
ENST00000370434.1 |
ABCC2
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| chr12_+_6493199 | 1.27 |
ENST00000228918.4
|
LTBR
|
lymphotoxin beta receptor (TNFR superfamily, member 3) |
| chr16_-_4401258 | 1.25 |
ENST00000577031.1
|
PAM16
|
presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| chr2_+_217498105 | 1.24 |
ENST00000233809.4
|
IGFBP2
|
insulin-like growth factor binding protein 2, 36kDa |
| chr22_-_37415475 | 1.22 |
ENST00000403892.3
ENST00000249042.3 ENST00000438203.1 |
TST
|
thiosulfate sulfurtransferase (rhodanese) |
| chr19_+_35630344 | 1.22 |
ENST00000455515.2
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr12_+_121163602 | 1.22 |
ENST00000411593.2
|
ACADS
|
acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| chr10_+_96443204 | 1.20 |
ENST00000339022.5
|
CYP2C18
|
cytochrome P450, family 2, subfamily C, polypeptide 18 |
| chr11_+_47279248 | 1.20 |
ENST00000449369.1
|
NR1H3
|
nuclear receptor subfamily 1, group H, member 3 |
| chr22_-_42526802 | 1.20 |
ENST00000359033.4
ENST00000389970.3 ENST00000360608.5 |
CYP2D6
|
cytochrome P450, family 2, subfamily D, polypeptide 6 |
| chr14_-_75643296 | 1.20 |
ENST00000303575.4
|
TMED10
|
transmembrane emp24-like trafficking protein 10 (yeast) |
| chr11_+_22688150 | 1.20 |
ENST00000454584.2
|
GAS2
|
growth arrest-specific 2 |
| chr1_-_160253998 | 1.20 |
ENST00000392220.2
|
PEX19
|
peroxisomal biogenesis factor 19 |
| chr11_+_47279504 | 1.19 |
ENST00000441012.2
ENST00000437276.1 ENST00000436029.1 ENST00000467728.1 ENST00000405853.3 |
NR1H3
|
nuclear receptor subfamily 1, group H, member 3 |
| chr4_-_7069760 | 1.19 |
ENST00000264954.4
|
GRPEL1
|
GrpE-like 1, mitochondrial (E. coli) |
| chr19_-_58864848 | 1.18 |
ENST00000263100.3
|
A1BG
|
alpha-1-B glycoprotein |
| chr3_-_197300194 | 1.18 |
ENST00000358186.2
ENST00000431056.1 |
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1 |
| chr13_+_113777105 | 1.17 |
ENST00000409306.1
ENST00000375551.3 ENST00000375559.3 |
F10
|
coagulation factor X |
| chr3_-_42917363 | 1.16 |
ENST00000437102.1
|
CYP8B1
|
cytochrome P450, family 8, subfamily B, polypeptide 1 |
| chr3_-_119396193 | 1.16 |
ENST00000484810.1
ENST00000497116.1 ENST00000261070.2 |
COX17
|
COX17 cytochrome c oxidase copper chaperone |
| chr9_+_127020202 | 1.16 |
ENST00000373600.3
ENST00000320246.5 |
NEK6
|
NIMA-related kinase 6 |
| chr19_+_35630022 | 1.16 |
ENST00000589209.1
|
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr6_+_143772060 | 1.14 |
ENST00000367591.4
|
PEX3
|
peroxisomal biogenesis factor 3 |
| chr1_-_197036364 | 1.14 |
ENST00000367412.1
|
F13B
|
coagulation factor XIII, B polypeptide |
| chr17_-_7531121 | 1.14 |
ENST00000573566.1
ENST00000269298.5 |
SAT2
|
spermidine/spermine N1-acetyltransferase family member 2 |
| chr12_+_100897130 | 1.13 |
ENST00000551379.1
ENST00000188403.7 ENST00000551184.1 |
NR1H4
|
nuclear receptor subfamily 1, group H, member 4 |
| chr11_-_66206260 | 1.13 |
ENST00000329819.4
ENST00000310999.7 ENST00000430466.2 |
MRPL11
|
mitochondrial ribosomal protein L11 |
| chr11_+_47279155 | 1.12 |
ENST00000444396.1
ENST00000457932.1 ENST00000412937.1 |
NR1H3
|
nuclear receptor subfamily 1, group H, member 3 |
| chr3_+_186560462 | 1.11 |
ENST00000412955.2
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing |
| chr19_-_51869592 | 1.11 |
ENST00000596253.1
ENST00000309244.4 |
ETFB
|
electron-transfer-flavoprotein, beta polypeptide |
| chr19_-_38806390 | 1.10 |
ENST00000589247.1
ENST00000329420.8 ENST00000591784.1 |
YIF1B
|
Yip1 interacting factor homolog B (S. cerevisiae) |
| chr3_+_186560476 | 1.10 |
ENST00000320741.2
ENST00000444204.2 |
ADIPOQ
|
adiponectin, C1Q and collagen domain containing |
| chr2_+_27719697 | 1.10 |
ENST00000264717.2
ENST00000424318.2 |
GCKR
|
glucokinase (hexokinase 4) regulator |
| chr20_-_43883197 | 1.09 |
ENST00000338380.2
|
SLPI
|
secretory leukocyte peptidase inhibitor |
| chr19_+_35630628 | 1.09 |
ENST00000588715.1
ENST00000588607.1 |
FXYD1
|
FXYD domain containing ion transport regulator 1 |
| chr7_+_80267949 | 1.09 |
ENST00000482059.2
|
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr16_-_10652993 | 1.09 |
ENST00000536829.1
|
EMP2
|
epithelial membrane protein 2 |
| chr9_-_27005686 | 1.08 |
ENST00000380055.5
|
LRRC19
|
leucine rich repeat containing 19 |
| chr4_+_111397216 | 1.07 |
ENST00000265162.5
|
ENPEP
|
glutamyl aminopeptidase (aminopeptidase A) |
| chr11_-_61348576 | 1.07 |
ENST00000263846.4
|
SYT7
|
synaptotagmin VII |
| chr14_+_105212297 | 1.03 |
ENST00000556623.1
ENST00000555674.1 |
ADSSL1
|
adenylosuccinate synthase like 1 |
| chr17_-_4852243 | 1.03 |
ENST00000225655.5
|
PFN1
|
profilin 1 |
| chr22_+_37415676 | 1.03 |
ENST00000401419.3
|
MPST
|
mercaptopyruvate sulfurtransferase |
| chr11_-_66675371 | 1.03 |
ENST00000393955.2
|
PC
|
pyruvate carboxylase |
| chr6_+_43737939 | 1.02 |
ENST00000372067.3
|
VEGFA
|
vascular endothelial growth factor A |
| chr22_+_46663895 | 1.02 |
ENST00000421359.1
|
TTC38
|
tetratricopeptide repeat domain 38 |
| chr22_+_46663861 | 1.01 |
ENST00000381031.3
ENST00000445282.2 |
TTC38
|
tetratricopeptide repeat domain 38 |
| chr22_+_37415728 | 1.01 |
ENST00000404802.3
|
MPST
|
mercaptopyruvate sulfurtransferase |
| chr15_+_91449971 | 1.01 |
ENST00000557865.1
|
MAN2A2
|
mannosidase, alpha, class 2A, member 2 |
| chr7_-_15601595 | 1.01 |
ENST00000342526.3
|
AGMO
|
alkylglycerol monooxygenase |
| chr11_-_61348292 | 1.01 |
ENST00000539008.1
ENST00000540677.1 ENST00000542836.1 ENST00000542670.1 ENST00000535826.1 ENST00000545053.1 |
SYT7
|
synaptotagmin VII |
| chr7_+_80267973 | 1.00 |
ENST00000394788.3
ENST00000447544.2 |
CD36
|
CD36 molecule (thrombospondin receptor) |
| chr9_+_139839686 | 1.00 |
ENST00000371634.2
|
C8G
|
complement component 8, gamma polypeptide |
| chr17_+_4692230 | 0.99 |
ENST00000331264.7
|
GLTPD2
|
glycolipid transfer protein domain containing 2 |
| chr22_+_37415700 | 0.99 |
ENST00000397129.1
|
MPST
|
mercaptopyruvate sulfurtransferase |
| chr22_+_25348671 | 0.99 |
ENST00000406486.4
|
KIAA1671
|
KIAA1671 |
| chr19_-_38806540 | 0.99 |
ENST00000592694.1
|
YIF1B
|
Yip1 interacting factor homolog B (S. cerevisiae) |
| chr14_+_77787227 | 0.98 |
ENST00000216465.5
ENST00000361389.4 ENST00000554279.1 ENST00000557639.1 ENST00000349555.3 ENST00000556627.1 ENST00000557053.1 |
GSTZ1
|
glutathione S-transferase zeta 1 |
| chr18_-_54318353 | 0.97 |
ENST00000590954.1
ENST00000540155.1 |
TXNL1
|
thioredoxin-like 1 |
| chr6_-_160147925 | 0.97 |
ENST00000535561.1
|
SOD2
|
superoxide dismutase 2, mitochondrial |
| chr19_-_4540486 | 0.97 |
ENST00000306390.6
|
LRG1
|
leucine-rich alpha-2-glycoprotein 1 |
| chr9_+_139839711 | 0.96 |
ENST00000224181.3
|
C8G
|
complement component 8, gamma polypeptide |
| chr12_+_132413798 | 0.96 |
ENST00000440818.2
ENST00000542167.2 ENST00000538037.1 ENST00000456665.2 |
PUS1
|
pseudouridylate synthase 1 |
| chr17_-_4852332 | 0.96 |
ENST00000572383.1
|
PFN1
|
profilin 1 |
| chr8_+_22224760 | 0.95 |
ENST00000359741.5
ENST00000520644.1 ENST00000240095.6 |
SLC39A14
|
solute carrier family 39 (zinc transporter), member 14 |
| chr17_+_53828333 | 0.95 |
ENST00000268896.5
|
PCTP
|
phosphatidylcholine transfer protein |
| chr19_+_44100727 | 0.95 |
ENST00000528387.1
ENST00000529930.1 ENST00000336564.4 ENST00000607544.1 ENST00000526798.1 |
ZNF576
SRRM5
|
zinc finger protein 576 serine/arginine repetitive matrix 5 |
| chr3_-_53878644 | 0.95 |
ENST00000481668.1
ENST00000467802.1 |
CHDH
|
choline dehydrogenase |
| chr7_-_74489609 | 0.95 |
ENST00000329959.4
ENST00000503250.2 ENST00000543840.1 |
WBSCR16
|
Williams-Beuren syndrome chromosome region 16 |
| chr12_+_57916466 | 0.95 |
ENST00000355673.3
|
MBD6
|
methyl-CpG binding domain protein 6 |
| chr12_+_113659234 | 0.94 |
ENST00000551096.1
ENST00000551099.1 ENST00000335509.6 ENST00000552897.1 ENST00000550785.1 ENST00000549279.1 |
TPCN1
|
two pore segment channel 1 |
| chr16_+_30075463 | 0.93 |
ENST00000562168.1
ENST00000569545.1 |
ALDOA
|
aldolase A, fructose-bisphosphate |
| chr2_-_31637560 | 0.92 |
ENST00000379416.3
|
XDH
|
xanthine dehydrogenase |
| chr19_-_38806560 | 0.91 |
ENST00000591755.1
ENST00000337679.8 ENST00000339413.6 |
YIF1B
|
Yip1 interacting factor homolog B (S. cerevisiae) |
| chr2_-_28113217 | 0.91 |
ENST00000444339.2
|
RBKS
|
ribokinase |
| chrX_+_2746850 | 0.91 |
ENST00000381163.3
ENST00000338623.5 ENST00000542787.1 |
GYG2
|
glycogenin 2 |
| chr22_+_37415776 | 0.90 |
ENST00000341116.3
ENST00000429360.2 ENST00000404393.1 |
MPST
|
mercaptopyruvate sulfurtransferase |
| chr16_+_56995854 | 0.90 |
ENST00000566128.1
|
CETP
|
cholesteryl ester transfer protein, plasma |
| chr6_+_80816342 | 0.89 |
ENST00000369760.4
ENST00000356489.5 ENST00000320393.6 |
BCKDHB
|
branched chain keto acid dehydrogenase E1, beta polypeptide |
| chr2_-_207024134 | 0.89 |
ENST00000457011.1
ENST00000440274.1 ENST00000432169.1 |
NDUFS1
|
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) |
| chr6_-_160148356 | 0.89 |
ENST00000401980.3
ENST00000545162.1 |
SOD2
|
superoxide dismutase 2, mitochondrial |
| chr8_+_22224811 | 0.88 |
ENST00000381237.1
|
SLC39A14
|
solute carrier family 39 (zinc transporter), member 14 |
| chr1_+_65613217 | 0.88 |
ENST00000545314.1
|
AK4
|
adenylate kinase 4 |
| chrX_+_2746818 | 0.88 |
ENST00000398806.3
|
GYG2
|
glycogenin 2 |
| chr17_+_53828381 | 0.88 |
ENST00000576183.1
|
PCTP
|
phosphatidylcholine transfer protein |
| chr1_-_16539094 | 0.87 |
ENST00000270747.3
|
ARHGEF19
|
Rho guanine nucleotide exchange factor (GEF) 19 |
| chr8_-_80942061 | 0.87 |
ENST00000519386.1
|
MRPS28
|
mitochondrial ribosomal protein S28 |
| chr6_-_135424186 | 0.86 |
ENST00000529882.1
|
HBS1L
|
HBS1-like (S. cerevisiae) |
| chr9_+_74764340 | 0.85 |
ENST00000376986.1
ENST00000358399.3 |
GDA
|
guanine deaminase |
| chr12_-_56236711 | 0.85 |
ENST00000409200.3
|
MMP19
|
matrix metallopeptidase 19 |
| chr12_-_56727676 | 0.85 |
ENST00000547572.1
ENST00000257931.5 ENST00000440411.3 |
PAN2
|
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) |
| chr11_-_111649074 | 0.85 |
ENST00000534218.1
|
RP11-108O10.2
|
RP11-108O10.2 |
| chr12_-_56236690 | 0.84 |
ENST00000322569.4
|
MMP19
|
matrix metallopeptidase 19 |
| chr3_-_9921934 | 0.84 |
ENST00000423850.1
|
CIDEC
|
cell death-inducing DFFA-like effector c |
| chr8_+_22225041 | 0.84 |
ENST00000289952.5
ENST00000524285.1 |
SLC39A14
|
solute carrier family 39 (zinc transporter), member 14 |
| chr1_+_153747746 | 0.83 |
ENST00000368661.3
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3 |
| chr17_-_1395954 | 0.83 |
ENST00000359786.5
|
MYO1C
|
myosin IC |
Network of associatons between targets according to the STRING database.
First level regulatory network of RXRA_NR2F6_NR2C2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.7 | 11.1 | GO:2000910 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
| 1.9 | 1.9 | GO:0010903 | negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) |
| 1.3 | 3.9 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 1.2 | 1.2 | GO:0009822 | alkaloid catabolic process(GO:0009822) |
| 1.1 | 2.2 | GO:0097018 | renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) |
| 1.1 | 4.3 | GO:0034445 | regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) |
| 1.0 | 5.2 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 1.0 | 6.1 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.8 | 5.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.7 | 3.0 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.7 | 2.2 | GO:0045720 | negative regulation of integrin biosynthetic process(GO:0045720) |
| 0.7 | 3.5 | GO:0090341 | negative regulation of secretion of lysosomal enzymes(GO:0090341) |
| 0.7 | 6.7 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.6 | 3.8 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.6 | 3.4 | GO:0006789 | bilirubin conjugation(GO:0006789) |
| 0.6 | 2.3 | GO:0006844 | acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616) |
| 0.6 | 3.9 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.5 | 12.1 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.5 | 1.6 | GO:0006147 | guanine catabolic process(GO:0006147) |
| 0.5 | 1.6 | GO:0050822 | peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823) |
| 0.5 | 3.6 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.5 | 3.6 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.5 | 2.1 | GO:1990927 | vesicle-mediated cholesterol transport(GO:0090119) calcium ion regulated lysosome exocytosis(GO:1990927) |
| 0.5 | 1.5 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
| 0.5 | 4.0 | GO:0010732 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 0.5 | 1.5 | GO:0070781 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
| 0.5 | 1.5 | GO:1903413 | cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641) |
| 0.5 | 1.4 | GO:0002894 | positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894) |
| 0.4 | 1.3 | GO:0050787 | antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787) |
| 0.4 | 4.2 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.4 | 2.8 | GO:0019474 | L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440) |
| 0.4 | 2.7 | GO:1902896 | terminal web assembly(GO:1902896) |
| 0.4 | 1.1 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 0.4 | 1.9 | GO:0003068 | age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571) |
| 0.3 | 2.4 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 0.3 | 5.5 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.3 | 1.0 | GO:0003169 | coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.3 | 2.0 | GO:0019626 | short-chain fatty acid catabolic process(GO:0019626) |
| 0.3 | 5.3 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.3 | 5.3 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.3 | 5.9 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.3 | 0.9 | GO:0006145 | purine nucleobase catabolic process(GO:0006145) |
| 0.3 | 1.8 | GO:0010728 | regulation of hydrogen peroxide biosynthetic process(GO:0010728) |
| 0.3 | 1.5 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.3 | 1.2 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.3 | 1.7 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.3 | 1.7 | GO:0070873 | regulation of glycogen metabolic process(GO:0070873) |
| 0.3 | 1.7 | GO:2000418 | positive regulation of eosinophil migration(GO:2000418) |
| 0.3 | 1.1 | GO:0001079 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
| 0.3 | 1.4 | GO:0034224 | cellular response to zinc ion starvation(GO:0034224) |
| 0.3 | 1.7 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 0.3 | 6.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 0.8 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.3 | 1.0 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.2 | 2.2 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.2 | 0.9 | GO:0019285 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.2 | 0.9 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.2 | 0.7 | GO:0045041 | B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041) |
| 0.2 | 1.3 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.2 | 1.0 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
| 0.2 | 2.3 | GO:0001554 | luteolysis(GO:0001554) |
| 0.2 | 2.0 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.2 | 0.2 | GO:0060730 | regulation of intestinal epithelial structure maintenance(GO:0060730) |
| 0.2 | 0.6 | GO:0046730 | induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528) |
| 0.2 | 0.4 | GO:0072179 | nephric duct formation(GO:0072179) |
| 0.2 | 1.7 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.2 | 2.1 | GO:0070543 | response to linoleic acid(GO:0070543) |
| 0.2 | 2.8 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.2 | 4.4 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.2 | 1.1 | GO:0033132 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.2 | 0.9 | GO:0019303 | D-ribose catabolic process(GO:0019303) |
| 0.2 | 0.7 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.2 | 1.1 | GO:0019556 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.2 | 1.6 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.2 | 3.6 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.2 | 2.3 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.2 | 1.5 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.2 | 4.7 | GO:0072189 | ureter development(GO:0072189) |
| 0.2 | 3.9 | GO:1903963 | arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963) |
| 0.1 | 10.4 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.1 | 0.6 | GO:0046166 | glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.1 | 0.6 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.1 | 2.7 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.1 | 0.4 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.1 | 3.8 | GO:0015879 | carnitine transport(GO:0015879) |
| 0.1 | 0.8 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.1 | 2.5 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 1.1 | GO:0002005 | angiotensin catabolic process in blood(GO:0002005) |
| 0.1 | 0.5 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.1 | 0.8 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
| 0.1 | 0.4 | GO:0035674 | tricarboxylic acid transmembrane transport(GO:0035674) |
| 0.1 | 0.4 | GO:1904404 | cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404) |
| 0.1 | 0.8 | GO:0006420 | arginyl-tRNA aminoacylation(GO:0006420) |
| 0.1 | 2.3 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 0.7 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.1 | 0.5 | GO:0060151 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.1 | 0.6 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
| 0.1 | 0.4 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
| 0.1 | 4.4 | GO:0036151 | phosphatidylcholine acyl-chain remodeling(GO:0036151) |
| 0.1 | 1.5 | GO:0045046 | protein import into peroxisome membrane(GO:0045046) |
| 0.1 | 0.2 | GO:0042494 | detection of bacterial lipoprotein(GO:0042494) |
| 0.1 | 0.9 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.1 | 4.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.1 | 0.5 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
| 0.1 | 2.7 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.1 | 0.8 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.1 | 0.7 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.1 | 0.5 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 0.8 | GO:0007008 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
| 0.1 | 0.3 | GO:0034371 | chylomicron remodeling(GO:0034371) |
| 0.1 | 0.7 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.1 | 0.7 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.1 | 0.3 | GO:2000397 | regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397) |
| 0.1 | 0.5 | GO:0014040 | positive regulation of Schwann cell differentiation(GO:0014040) |
| 0.1 | 1.0 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.1 | 1.1 | GO:0070836 | caveola assembly(GO:0070836) |
| 0.1 | 0.2 | GO:0009644 | response to high light intensity(GO:0009644) |
| 0.1 | 2.3 | GO:0050961 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.1 | 1.8 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 1.5 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.1 | 0.3 | GO:0002879 | positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879) |
| 0.1 | 4.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 0.3 | GO:0006669 | sphinganine-1-phosphate biosynthetic process(GO:0006669) |
| 0.1 | 0.2 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.1 | 0.4 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.1 | 0.5 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.1 | 0.5 | GO:1904058 | positive regulation of sensory perception of pain(GO:1904058) |
| 0.1 | 0.8 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.1 | 0.6 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.1 | 0.3 | GO:0061030 | epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) |
| 0.1 | 1.5 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 2.8 | GO:0006735 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 0.4 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.1 | 2.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.1 | 0.3 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.1 | 0.6 | GO:0036155 | acylglycerol acyl-chain remodeling(GO:0036155) |
| 0.1 | 0.7 | GO:0042262 | DNA protection(GO:0042262) |
| 0.1 | 0.6 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 0.4 | GO:0055129 | L-proline biosynthetic process(GO:0055129) |
| 0.1 | 0.5 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.1 | 1.5 | GO:0010226 | response to lithium ion(GO:0010226) |
| 0.1 | 0.4 | GO:0060751 | epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) |
| 0.1 | 0.2 | GO:0044854 | plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) |
| 0.1 | 0.3 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 0.3 | GO:1902445 | regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) |
| 0.1 | 5.7 | GO:0009250 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.1 | 0.2 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747) |
| 0.1 | 0.8 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
| 0.1 | 0.2 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.1 | 1.7 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.1 | 0.1 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.0 | 0.7 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.4 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.0 | 0.1 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.0 | 0.1 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.0 | 0.1 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.0 | 0.4 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.0 | 0.5 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 0.9 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.2 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.0 | 1.0 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 0.0 | 0.1 | GO:2000588 | positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588) |
| 0.0 | 0.7 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.0 | 1.6 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 1.3 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.0 | 0.4 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
| 0.0 | 5.0 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 1.0 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 0.7 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.0 | 0.5 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
| 0.0 | 0.7 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 2.5 | GO:0006656 | phosphatidylcholine biosynthetic process(GO:0006656) |
| 0.0 | 0.5 | GO:0071550 | death-inducing signaling complex assembly(GO:0071550) |
| 0.0 | 0.8 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 1.0 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.0 | 0.6 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.0 | 0.1 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
| 0.0 | 4.7 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.7 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.0 | 0.9 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
| 0.0 | 0.8 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 1.7 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.2 | GO:0071163 | DNA replication preinitiation complex assembly(GO:0071163) |
| 0.0 | 0.1 | GO:2001176 | mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178) |
| 0.0 | 0.2 | GO:1901376 | mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788) |
| 0.0 | 0.7 | GO:1904294 | positive regulation of ERAD pathway(GO:1904294) |
| 0.0 | 0.2 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.0 | 0.4 | GO:0002084 | protein depalmitoylation(GO:0002084) |
| 0.0 | 0.4 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.0 | 1.2 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.1 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.0 | 0.4 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.0 | 0.4 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.4 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 1.1 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.0 | 0.3 | GO:0072719 | copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719) |
| 0.0 | 0.2 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 0.2 | GO:0071501 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.0 | 1.8 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.8 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.6 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.0 | 0.3 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.0 | 0.9 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.0 | 0.1 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.0 | 0.2 | GO:1901341 | activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.1 | GO:1904100 | regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100) |
| 0.0 | 0.8 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.5 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 2.2 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.0 | 0.1 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.0 | 0.3 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) positive regulation of inclusion body assembly(GO:0090261) |
| 0.0 | 1.2 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
| 0.0 | 0.4 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.0 | 0.2 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.0 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.3 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.8 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.0 | 1.0 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.0 | 0.3 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.0 | 0.3 | GO:1990845 | adaptive thermogenesis(GO:1990845) |
| 0.0 | 0.8 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 0.1 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.0 | 0.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.1 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.0 | 1.0 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.5 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.0 | 0.2 | GO:0042045 | epithelial fluid transport(GO:0042045) |
| 0.0 | 0.5 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 0.2 | GO:0009253 | peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) |
| 0.0 | 0.1 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.0 | 1.2 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.0 | 0.3 | GO:0021692 | cerebellar Purkinje cell layer morphogenesis(GO:0021692) |
| 0.0 | 0.8 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.0 | 0.0 | GO:0070245 | positive regulation of thymocyte apoptotic process(GO:0070245) |
| 0.0 | 0.1 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.0 | 0.2 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.0 | 0.3 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
| 0.0 | 0.4 | GO:0018107 | peptidyl-threonine phosphorylation(GO:0018107) |
| 0.0 | 0.3 | GO:0001935 | endothelial cell proliferation(GO:0001935) |
| 0.0 | 0.7 | GO:0045737 | positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) |
| 0.0 | 0.6 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.0 | 0.7 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.3 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 1.3 | GO:0046426 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.2 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.0 | 0.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.0 | 0.2 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.0 | 0.3 | GO:0046519 | sphingoid metabolic process(GO:0046519) |
| 0.0 | 0.1 | GO:0045621 | positive regulation of T cell differentiation(GO:0045582) positive regulation of lymphocyte differentiation(GO:0045621) |
| 0.0 | 0.1 | GO:0016267 | O-glycan processing, core 1(GO:0016267) |
| 0.0 | 0.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.1 | GO:1903659 | regulation of complement-dependent cytotoxicity(GO:1903659) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.3 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.0 | 0.1 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 0.6 | GO:0006636 | unsaturated fatty acid biosynthetic process(GO:0006636) |
| 0.0 | 0.1 | GO:0086043 | bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043) |
| 0.0 | 0.1 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
| 0.0 | 0.4 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.5 | GO:0007031 | peroxisome organization(GO:0007031) |
| 0.0 | 0.3 | GO:0006939 | smooth muscle contraction(GO:0006939) |
| 0.0 | 0.1 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.4 | GO:0009649 | entrainment of circadian clock(GO:0009649) |
| 0.0 | 0.2 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.0 | 0.1 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.0 | 0.1 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.0 | 0.3 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.1 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 0.4 | GO:0039694 | viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) |
| 0.0 | 0.8 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.0 | 0.1 | GO:0060992 | response to fungicide(GO:0060992) |
| 0.0 | 0.7 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.8 | 3.9 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.5 | 9.9 | GO:0042627 | chylomicron(GO:0042627) |
| 0.5 | 2.0 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.4 | 1.5 | GO:0031251 | PAN complex(GO:0031251) |
| 0.3 | 2.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.3 | 3.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.3 | 0.8 | GO:0071749 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 0.2 | 1.6 | GO:0042825 | TAP complex(GO:0042825) |
| 0.2 | 1.7 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.2 | 0.8 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.2 | 2.0 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.2 | 1.1 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 0.2 | 2.1 | GO:0032009 | early phagosome(GO:0032009) |
| 0.2 | 1.0 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 5.2 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.1 | 0.4 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.1 | 0.8 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.1 | 3.7 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.1 | 0.7 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 1.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 14.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.5 | GO:0000839 | Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839) |
| 0.1 | 1.1 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.1 | 1.5 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 1.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 1.0 | GO:0045240 | dihydrolipoyl dehydrogenase complex(GO:0045240) |
| 0.1 | 0.8 | GO:0034715 | pICln-Sm protein complex(GO:0034715) |
| 0.1 | 0.7 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.5 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 2.1 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 1.8 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 2.8 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 0.7 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 5.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 2.6 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 0.4 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.1 | 0.6 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.1 | 0.2 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.1 | 0.7 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 40.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 1.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 0.6 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 12.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 1.1 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 0.4 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.1 | 1.6 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.3 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.1 | 0.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 1.0 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.1 | 0.8 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 0.9 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 1.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
| 0.0 | 0.1 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.0 | 2.0 | GO:0032994 | protein-lipid complex(GO:0032994) |
| 0.0 | 0.2 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.0 | 2.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 1.2 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.0 | 3.4 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 4.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.1 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 0.1 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.0 | 0.4 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 3.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 4.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 2.0 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 0.8 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 5.1 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.7 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.0 | 0.1 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
| 0.0 | 0.2 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 2.2 | GO:0044439 | microbody part(GO:0044438) peroxisomal part(GO:0044439) |
| 0.0 | 2.1 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.3 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.3 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 0.5 | GO:0031264 | death-inducing signaling complex(GO:0031264) |
| 0.0 | 1.5 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 0.4 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.0 | 1.8 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 0.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 1.8 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 24.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.3 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.6 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 0.0 | 0.3 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.0 | 0.7 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 0.6 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 1.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.0 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 3.2 | GO:0061695 | transferase complex, transferring phosphorus-containing groups(GO:0061695) |
| 0.0 | 19.6 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 0.1 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 1.1 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.4 | GO:1902562 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.0 | 2.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.1 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.7 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 1.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 0.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 0.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.6 | GO:0016459 | myosin complex(GO:0016459) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 13.0 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 1.8 | 5.3 | GO:0004174 | electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649) |
| 1.3 | 3.9 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 1.1 | 6.7 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 1.0 | 3.0 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 1.0 | 3.9 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.9 | 4.7 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 0.8 | 2.4 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.8 | 3.1 | GO:0001855 | complement component C4b binding(GO:0001855) |
| 0.7 | 3.6 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.7 | 5.0 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.7 | 2.1 | GO:0047025 | 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025) |
| 0.7 | 4.2 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.6 | 4.5 | GO:0031849 | olfactory receptor binding(GO:0031849) |
| 0.6 | 4.9 | GO:0004466 | long-chain-acyl-CoA dehydrogenase activity(GO:0004466) |
| 0.6 | 1.2 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.6 | 2.4 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.6 | 5.9 | GO:0005497 | androgen binding(GO:0005497) |
| 0.6 | 2.3 | GO:0015227 | acyl carnitine transmembrane transporter activity(GO:0015227) |
| 0.6 | 1.7 | GO:0003826 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.6 | 2.8 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.5 | 2.2 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 0.5 | 1.6 | GO:0008892 | guanine deaminase activity(GO:0008892) |
| 0.5 | 4.3 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.5 | 2.8 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.4 | 2.2 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.4 | 5.7 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.4 | 4.8 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
| 0.4 | 3.5 | GO:0032810 | sterol response element binding(GO:0032810) |
| 0.4 | 1.5 | GO:0008112 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
| 0.4 | 1.1 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 0.3 | 1.0 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
| 0.3 | 1.7 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.3 | 1.3 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.3 | 2.7 | GO:0005124 | scavenger receptor binding(GO:0005124) |
| 0.3 | 1.0 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.3 | 2.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.3 | 2.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.3 | 1.6 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.3 | 3.1 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.3 | 1.2 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.3 | 1.2 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.3 | 1.1 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
| 0.3 | 0.8 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
| 0.3 | 0.8 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
| 0.3 | 8.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.3 | 3.1 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.2 | 2.7 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 1.4 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 0.7 | GO:0004108 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
| 0.2 | 1.2 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.2 | 0.7 | GO:0015361 | low-affinity sodium:dicarboxylate symporter activity(GO:0015361) |
| 0.2 | 2.0 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.2 | 2.0 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.2 | 2.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 2.9 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.2 | 1.0 | GO:0004572 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572) |
| 0.2 | 0.6 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) |
| 0.2 | 2.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.2 | 6.5 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.2 | 6.3 | GO:0001848 | complement binding(GO:0001848) |
| 0.2 | 2.4 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.2 | 3.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.2 | 5.5 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.2 | 2.2 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.2 | 1.6 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.2 | 0.5 | GO:0030626 | U12 snRNA binding(GO:0030626) |
| 0.2 | 0.8 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.2 | 0.9 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.1 | 0.6 | GO:0015207 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 0.1 | 1.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.1 | 2.6 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.1 | 0.4 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.1 | 3.0 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.1 | 0.6 | GO:0033981 | D-dopachrome decarboxylase activity(GO:0033981) |
| 0.1 | 1.0 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.1 | 2.3 | GO:0033691 | sialic acid binding(GO:0033691) |
| 0.1 | 0.7 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.1 | 0.9 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.1 | 0.8 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
| 0.1 | 0.4 | GO:0061663 | NEDD8 ligase activity(GO:0061663) |
| 0.1 | 0.8 | GO:0004814 | arginine-tRNA ligase activity(GO:0004814) |
| 0.1 | 0.4 | GO:0008441 | 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441) |
| 0.1 | 0.6 | GO:0050252 | retinol O-fatty-acyltransferase activity(GO:0050252) |
| 0.1 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.1 | 0.8 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.7 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
| 0.1 | 0.9 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 0.1 | 0.5 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 0.1 | 2.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 1.0 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 0.6 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 1.2 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 0.7 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.1 | 1.2 | GO:0000268 | peroxisome targeting sequence binding(GO:0000268) |
| 0.1 | 0.7 | GO:0030614 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
| 0.1 | 4.1 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.1 | 0.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 1.7 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.1 | 1.0 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.1 | 0.7 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 13.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.4 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
| 0.1 | 4.1 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.1 | 1.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 1.0 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.1 | 1.3 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 1.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 0.4 | GO:0015137 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
| 0.1 | 0.3 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
| 0.1 | 0.3 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.1 | 3.4 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 0.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.1 | 0.7 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.1 | 0.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 0.8 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.8 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.1 | 0.3 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 1.7 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.1 | 0.2 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.1 | 0.2 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.1 | 0.1 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.0 | 0.4 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.0 | 3.9 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 0.3 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 0.4 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.0 | 4.2 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.0 | 1.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.3 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
| 0.0 | 0.5 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 3.1 | GO:0098531 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.0 | 0.7 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.0 | 0.4 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.7 | GO:0015923 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
| 0.0 | 1.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.9 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.7 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.3 | GO:0017077 | oxidative phosphorylation uncoupler activity(GO:0017077) |
| 0.0 | 0.8 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.2 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.0 | 0.2 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.0 | 0.5 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.1 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.0 | 0.8 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617) |
| 0.0 | 1.3 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.1 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 10.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 1.2 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.8 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 1.1 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.0 | 0.4 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.0 | 0.1 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
| 0.0 | 2.1 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 0.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.2 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.2 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 0.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.5 | GO:0071949 | FAD binding(GO:0071949) |
| 0.0 | 0.9 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
| 0.0 | 0.1 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.0 | 0.6 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.4 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
| 0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 0.6 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.0 | 0.1 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
| 0.0 | 0.4 | GO:0098847 | sequence-specific single stranded DNA binding(GO:0098847) |
| 0.0 | 0.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.9 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 0.2 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.3 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 1.1 | GO:0050660 | flavin adenine dinucleotide binding(GO:0050660) |
| 0.0 | 0.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.3 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.1 | GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) |
| 0.0 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.7 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.3 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.0 | 0.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 3.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.1 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.0 | 0.6 | GO:0030546 | receptor activator activity(GO:0030546) |
| 0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 18.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 4.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 7.2 | ST ADRENERGIC | Adrenergic Pathway |
| 0.1 | 0.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 7.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 1.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 4.8 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 4.7 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 3.1 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 1.1 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 19.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.4 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.0 | 1.3 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 5.0 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 2.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.4 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.7 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.4 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 2.4 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.3 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 1.5 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.3 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 1.0 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 0.2 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 0.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.4 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 3.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 11.4 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.5 | 13.8 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.5 | 15.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.5 | 9.6 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.5 | 5.0 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.4 | 7.5 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.2 | 3.5 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol |
| 0.2 | 14.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 3.0 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.2 | 4.1 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 2.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.1 | 2.8 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.1 | 2.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 9.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 3.4 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 12.2 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 7.0 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.1 | 4.3 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.1 | 8.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.2 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 2.2 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.0 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 10.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.0 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 1.3 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 0.8 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.1 | 1.1 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 1.3 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 1.6 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 1.0 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.0 | 0.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 1.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 2.2 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.0 | 1.2 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.7 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.4 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.3 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.4 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 1.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.2 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 0.1 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.8 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.3 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.0 | 0.5 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.3 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.5 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.4 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 3.4 | REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM | Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism |
| 0.0 | 0.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.4 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 1.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.3 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.4 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.5 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.4 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 1.1 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.0 | 0.3 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 0.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.0 | 0.7 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |