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Illumina Body Map 2: averaged replicates

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Results for SIX5_SMARCC2_HCFC1

Z-value: 4.86

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Transcription factors associated with SIX5_SMARCC2_HCFC1

Gene Symbol Gene ID Gene Info
ENSG00000177045.6 SIX homeobox 5
ENSG00000139613.7 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
ENSG00000172534.9 host cell factor C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX5hg19_v2_chr19_-_46272106_46272115-0.291.1e-01Click!
HCFC1hg19_v2_chrX_-_153236819_153236978-0.261.5e-01Click!
SMARCC2hg19_v2_chr12_-_56583243_565832930.038.9e-01Click!

Activity profile of SIX5_SMARCC2_HCFC1 motif

Sorted Z-values of SIX5_SMARCC2_HCFC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_4791722 11.82 ENST00000269856.3
fem-1 homolog a (C. elegans)
chr19_-_51014345 9.03 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
Josephin domain containing 2
chr1_+_45965725 8.77 ENST00000401061.4
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr19_-_51014460 7.64 ENST00000595669.1
Josephin domain containing 2
chr4_-_8160510 6.58 ENST00000407564.3
ENST00000361737.5
ENST00000296372.8
ENST00000545242.1
ENST00000546334.1
ENST00000318888.4
ENST00000428004.2
actin binding LIM protein family, member 2
chr4_-_8160416 6.23 ENST00000505872.1
ENST00000447017.2
ENST00000341937.5
ENST00000361581.5
actin binding LIM protein family, member 2
chr19_-_51014588 5.63 ENST00000598418.1
Josephin domain containing 2
chr1_-_2458026 5.62 ENST00000435556.3
ENST00000378466.3
pantothenate kinase 4
chr8_-_28747424 5.62 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
integrator complex subunit 9
chr12_+_107168418 5.25 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8 guanine nucleotide exchange factor B
chr1_+_202317855 5.05 ENST00000356764.2
protein phosphatase 1, regulatory subunit 12B
chr3_-_46037299 4.93 ENST00000296137.2
FYVE and coiled-coil domain containing 1
chr12_+_120740119 4.88 ENST00000536460.1
ENST00000202967.4
sirtuin 4
chr11_-_73309112 4.87 ENST00000450446.2
family with sequence similarity 168, member A
chr11_-_73309228 4.86 ENST00000356467.4
ENST00000064778.4
family with sequence similarity 168, member A
chr1_-_156710916 4.72 ENST00000368211.4
mitochondrial ribosomal protein L24
chr12_+_107168342 4.70 ENST00000392837.4
RIC8 guanine nucleotide exchange factor B
chr7_-_132766800 4.50 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr7_-_132766818 4.46 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr4_-_152682129 4.46 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112 homolog (yeast)
chr3_+_69788576 4.35 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr19_+_35225060 4.35 ENST00000599244.1
ENST00000392232.3
zinc finger protein 181
chr10_-_104262460 4.30 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr5_-_145562147 4.28 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr12_+_6961279 4.18 ENST00000229268.8
ENST00000389231.5
ENST00000542087.1
ubiquitin specific peptidase 5 (isopeptidase T)
chr10_-_104262426 4.09 ENST00000487599.1
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr2_+_63816126 4.05 ENST00000454035.1
malate dehydrogenase 1, NAD (soluble)
chr19_-_47551836 3.96 ENST00000253047.6
transmembrane protein 160
chr20_-_62587735 3.93 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
uridine-cytidine kinase 1-like 1
chr1_-_156710859 3.93 ENST00000361531.2
ENST00000412846.1
mitochondrial ribosomal protein L24
chr19_+_1241732 3.91 ENST00000215375.2
ENST00000395633.1
ENST00000591660.1
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr9_+_134165063 3.89 ENST00000372264.3
phosphatidic acid phosphatase type 2 domain containing 3
chr1_-_26324534 3.88 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
platelet-activating factor acetylhydrolase 2, 40kDa
chr17_+_7358889 3.87 ENST00000575379.1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr6_-_41703296 3.71 ENST00000373033.1
transcription factor EB
chr19_-_39390350 3.67 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr16_+_46918235 3.64 ENST00000340124.4
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr2_+_63816269 3.60 ENST00000432309.1
malate dehydrogenase 1, NAD (soluble)
chr13_-_41837620 3.53 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
mitochondrial translational release factor 1
chr6_+_42531798 3.52 ENST00000372903.2
ENST00000372899.1
ENST00000372901.1
ubiquitin protein ligase E3 component n-recognin 2
chr14_-_73493784 3.52 ENST00000553891.1
zinc finger, FYVE domain containing 1
chr16_+_2009500 3.44 ENST00000268668.6
ENST00000543683.2
ENST00000569148.1
ENST00000570172.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
chr1_+_156024525 3.42 ENST00000368305.4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr12_+_861717 3.41 ENST00000535572.1
WNK lysine deficient protein kinase 1
chr16_-_67840442 3.38 ENST00000536251.1
ENST00000448631.2
ENST00000602677.1
ENST00000411657.2
ENST00000425512.2
ENST00000317506.3
RAN binding protein 10
chr12_-_54121261 3.33 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr9_+_134165195 3.33 ENST00000372261.1
phosphatidic acid phosphatase type 2 domain containing 3
chr17_+_67410832 3.32 ENST00000590474.1
mitogen-activated protein kinase kinase 6
chrX_-_130037162 3.31 ENST00000432489.1
ecto-NOX disulfide-thiol exchanger 2
chr2_+_63816295 3.31 ENST00000539945.1
ENST00000544381.1
malate dehydrogenase 1, NAD (soluble)
chr7_+_92861653 3.30 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
coiled-coil domain containing 132
chr5_+_175815732 3.29 ENST00000274787.2
HIG1 hypoxia inducible domain family, member 2A
chr17_-_21117902 3.24 ENST00000317635.5
transmembrane protein 11
chr7_-_150924121 3.22 ENST00000441774.1
ENST00000222388.2
ENST00000287844.2
ATP-binding cassette, sub-family F (GCN20), member 2
chr14_-_73493825 3.21 ENST00000318876.5
ENST00000556143.1
zinc finger, FYVE domain containing 1
chr8_+_17780346 3.19 ENST00000325083.8
pericentriolar material 1
chr19_-_39390440 3.14 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr15_-_55700457 3.10 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr2_+_217277137 3.10 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr16_+_53738053 3.09 ENST00000394647.3
fat mass and obesity associated
chr8_-_28747717 3.09 ENST00000416984.2
integrator complex subunit 9
chr1_-_93645818 3.09 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr7_-_75988321 3.08 ENST00000307630.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr19_-_47354023 3.08 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
adaptor-related protein complex 2, sigma 1 subunit
chr2_-_85581701 3.06 ENST00000295802.4
retinol saturase (all-trans-retinol 13,14-reductase)
chr11_-_66139199 3.05 ENST00000357440.2
solute carrier family 29 (equilibrative nucleoside transporter), member 2
chr8_+_17780483 3.04 ENST00000517730.1
ENST00000518537.1
ENST00000523055.1
ENST00000519253.1
pericentriolar material 1
chr2_-_85581623 2.98 ENST00000449375.1
ENST00000409984.2
ENST00000457495.2
ENST00000263854.6
retinol saturase (all-trans-retinol 13,14-reductase)
chr2_+_63816087 2.98 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
malate dehydrogenase 1, NAD (soluble)
chr8_+_145159846 2.91 ENST00000532522.1
ENST00000527572.1
ENST00000527058.1
MAF1 homolog (S. cerevisiae)
chrX_-_130037198 2.89 ENST00000370935.1
ENST00000338144.3
ENST00000394363.1
ecto-NOX disulfide-thiol exchanger 2
chr10_+_60094735 2.87 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr14_+_36295638 2.85 ENST00000543183.1
breast cancer metastasis-suppressor 1-like
chr19_-_47354082 2.83 ENST00000593442.1
ENST00000263270.6
adaptor-related protein complex 2, sigma 1 subunit
chr19_-_42746714 2.83 ENST00000222330.3
glycogen synthase kinase 3 alpha
chr13_-_30881621 2.82 ENST00000380615.3
katanin p60 subunit A-like 1
chr12_-_54121212 2.82 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr18_-_43684186 2.76 ENST00000590406.1
ENST00000282050.2
ENST00000590324.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr19_-_5680499 2.74 ENST00000587589.1
chromosome 19 open reading frame 70
chr1_+_156737292 2.70 ENST00000271526.4
ENST00000353233.3
papillary renal cell carcinoma (translocation-associated)
chrX_-_106362013 2.68 ENST00000372487.1
ENST00000372479.3
ENST00000203616.8
RNA binding motif protein 41
chr1_+_156024552 2.68 ENST00000368304.5
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr4_+_159593418 2.67 ENST00000507475.1
ENST00000307738.5
electron-transferring-flavoprotein dehydrogenase
chr18_-_43684230 2.63 ENST00000592989.1
ENST00000589869.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr7_-_150754935 2.62 ENST00000297518.4
cyclin-dependent kinase 5
chr7_+_102389434 2.59 ENST00000409231.3
ENST00000418198.1
family with sequence similarity 185, member A
chr1_-_114355083 2.59 ENST00000261441.5
round spermatid basic protein 1
chr17_+_41322483 2.58 ENST00000341165.6
ENST00000586650.1
ENST00000422280.1
neighbor of BRCA1 gene 1
chr18_+_71815743 2.58 ENST00000169551.6
ENST00000580087.1
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr7_+_74072288 2.58 ENST00000443166.1
general transcription factor IIi
chr2_+_217277466 2.57 ENST00000358207.5
ENST00000434435.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr22_+_30163340 2.56 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr3_+_133524459 2.55 ENST00000484684.1
signal recognition particle receptor, B subunit
chr12_+_56660633 2.53 ENST00000308197.5
coenzyme Q10 homolog A (S. cerevisiae)
chr7_-_74867509 2.53 ENST00000426327.3
GATS protein-like 2
chr8_-_109799793 2.52 ENST00000297459.3
transmembrane protein 74
chr4_-_2965052 2.52 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14 nucleolar protein
chr11_+_57425209 2.52 ENST00000533905.1
ENST00000525602.1
ENST00000302731.4
cleavage and polyadenylation factor I subunit 1
chr1_-_185126037 2.51 ENST00000367506.5
ENST00000367504.3
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr9_+_116037922 2.51 ENST00000374198.4
pre-mRNA processing factor 4
chr1_+_44412577 2.50 ENST00000372343.3
importin 13
chrX_-_2418936 2.45 ENST00000461691.1
ENST00000381223.4
ENST00000381222.2
ENST00000412516.2
ENST00000334651.5
zinc finger, BED-type containing 1
dehydrogenase/reductase (SDR family) X-linked
chr19_-_39390212 2.45 ENST00000437828.1
sirtuin 2
chr1_+_1550795 2.41 ENST00000520777.1
ENST00000357210.4
ENST00000360522.4
ENST00000378710.3
ENST00000355826.5
ENST00000518681.1
ENST00000505820.2
mindbomb E3 ubiquitin protein ligase 2
chr9_-_138853156 2.40 ENST00000371756.3
UBA domain containing 1
chr2_-_69870747 2.40 ENST00000409068.1
AP2 associated kinase 1
chr17_+_41323204 2.40 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
neighbor of BRCA1 gene 1
chr3_-_14166316 2.39 ENST00000396914.3
ENST00000295767.5
coiled-coil-helix-coiled-coil-helix domain containing 4
chr15_-_65477637 2.39 ENST00000300107.3
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr3_-_183735651 2.38 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr16_+_2097403 2.38 ENST00000219476.3
tuberous sclerosis 2
chr15_+_55700741 2.38 ENST00000569691.1
chromosome 15 open reading frame 65
chr19_+_35225121 2.37 ENST00000595708.1
ENST00000593781.1
zinc finger protein 181
chr9_-_111882195 2.36 ENST00000374586.3
transmembrane protein 245
chr19_-_5680891 2.36 ENST00000309324.4
chromosome 19 open reading frame 70
chr13_-_41768654 2.35 ENST00000379483.3
kelch repeat and BTB (POZ) domain containing 7
chr10_+_124134201 2.35 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_+_95612006 2.32 ENST00000551311.1
ENST00000546445.1
vezatin, adherens junctions transmembrane protein
chr1_-_115300579 2.32 ENST00000358528.4
ENST00000525132.1
cold shock domain containing E1, RNA-binding
chr13_-_114145253 2.28 ENST00000496873.1
ENST00000478244.1
DCN1, defective in cullin neddylation 1, domain containing 2
chr6_-_88411911 2.27 ENST00000257787.5
akirin 2
chr18_+_9475001 2.27 ENST00000019317.4
ralA binding protein 1
chr19_-_5680231 2.25 ENST00000587950.1
chromosome 19 open reading frame 70
chr6_-_41703952 2.25 ENST00000358871.2
ENST00000403298.4
transcription factor EB
chr1_-_144932316 2.23 ENST00000313431.9
phosphodiesterase 4D interacting protein
chr12_+_95611536 2.23 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chr15_+_41099919 2.21 ENST00000561617.1
zinc finger, FYVE domain containing 19
chr4_+_159593271 2.21 ENST00000512251.1
ENST00000511912.1
electron-transferring-flavoprotein dehydrogenase
chr20_-_2489542 2.19 ENST00000421216.1
ENST00000381253.1
zinc finger protein 343
chr19_-_36980337 2.17 ENST00000434377.2
ENST00000424129.2
ENST00000452939.1
ENST00000427002.1
zinc finger protein 566
chr11_+_134123389 2.16 ENST00000281182.4
ENST00000537423.1
ENST00000543332.1
ENST00000374752.4
acyl-CoA dehydrogenase family, member 8
chr20_+_55966444 2.16 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chr3_+_183353356 2.16 ENST00000242810.6
ENST00000493074.1
ENST00000437402.1
ENST00000454495.2
ENST00000473045.1
ENST00000468101.1
ENST00000427201.2
ENST00000482138.1
ENST00000454652.2
kelch-like family member 24
chr1_-_235667716 2.16 ENST00000313984.3
ENST00000366600.3
beta-1,3-N-acetylgalactosaminyltransferase 2
chr7_-_135194822 2.13 ENST00000428680.2
ENST00000315544.5
ENST00000423368.2
ENST00000451834.1
ENST00000361528.4
ENST00000356162.4
ENST00000541284.1
CCR4-NOT transcription complex, subunit 4
chr10_+_74870206 2.13 ENST00000357321.4
ENST00000349051.5
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr1_-_115300592 2.12 ENST00000261443.5
ENST00000534699.1
ENST00000339438.6
ENST00000529046.1
ENST00000525970.1
ENST00000369530.1
ENST00000530886.1
cold shock domain containing E1, RNA-binding
chr3_+_184016986 2.11 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr17_+_43239231 2.11 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr12_+_9102632 2.11 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr19_-_19249255 2.11 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
transmembrane protein 161A
chr11_-_113644491 2.10 ENST00000200135.3
zw10 kinetochore protein
chr5_-_36152031 2.10 ENST00000296603.4
LMBR1 domain containing 2
chr1_-_144932464 2.08 ENST00000479408.2
phosphodiesterase 4D interacting protein
chr12_+_56661033 2.08 ENST00000433805.2
coenzyme Q10 homolog A (S. cerevisiae)
chr3_+_158991025 2.08 ENST00000337808.6
IQCJ-SCHIP1 readthrough
chr15_-_55700522 2.06 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr4_-_88141615 2.06 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
kelch-like family member 8
chr1_+_1551220 2.05 ENST00000378712.1
mindbomb E3 ubiquitin protein ligase 2
chr2_-_242447732 2.03 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
serine/threonine kinase 25
chr11_-_63933504 2.03 ENST00000255681.6
MACRO domain containing 1
chr5_+_178487354 2.03 ENST00000315475.6
zinc finger protein 354C
chr14_-_77923897 2.02 ENST00000343765.2
ENST00000327028.4
ENST00000556412.1
ENST00000557466.1
ENST00000448935.2
ENST00000553888.1
ENST00000557658.1
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr6_-_163148780 2.01 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
parkin RBR E3 ubiquitin protein ligase
chr17_+_27046988 1.99 ENST00000496182.1
ribosomal protein L23a
chr3_-_50329990 1.99 ENST00000417626.2
interferon-related developmental regulator 2
chr1_-_151138422 1.98 ENST00000440902.2
LysM, putative peptidoglycan-binding, domain containing 1
chr20_-_35724388 1.97 ENST00000344359.3
ENST00000373664.3
retinoblastoma-like 1 (p107)
chr15_+_75182346 1.97 ENST00000569931.1
ENST00000352410.4
ENST00000566377.1
ENST00000569233.1
ENST00000567132.1
ENST00000564633.1
ENST00000568907.1
ENST00000563422.1
ENST00000564003.1
ENST00000562800.1
ENST00000563786.1
ENST00000535694.1
ENST00000323744.6
ENST00000568828.1
ENST00000562606.1
ENST00000565576.1
ENST00000567570.1
mannose phosphate isomerase
chr2_-_170430366 1.97 ENST00000453153.2
ENST00000445210.1
FAST kinase domains 1
chr2_-_170430277 1.96 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr11_-_71791518 1.96 ENST00000537217.1
ENST00000366394.3
ENST00000358965.6
ENST00000546131.1
ENST00000543937.1
ENST00000368959.5
ENST00000541641.1
nuclear mitotic apparatus protein 1
chr2_-_69870835 1.95 ENST00000409085.4
ENST00000406297.3
AP2 associated kinase 1
chr16_-_4588822 1.94 ENST00000564828.1
cell death-inducing p53 target 1
chr4_-_186347099 1.93 ENST00000505357.1
ENST00000264689.6
UFM1-specific peptidase 2
chr10_+_74870253 1.92 ENST00000544879.1
ENST00000537969.1
ENST00000372997.3
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr2_+_217277271 1.91 ENST00000425815.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr17_+_43138664 1.91 ENST00000258960.2
N-myristoyltransferase 1
chr15_-_34635314 1.91 ENST00000557912.1
ENST00000328848.4
NOP10 ribonucleoprotein
chrX_+_49091920 1.91 ENST00000376227.3
coiled-coil domain containing 22
chr10_-_121356518 1.91 ENST00000369092.4
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr17_-_5015129 1.91 ENST00000575898.1
ENST00000416429.2
zinc finger protein 232
chr5_+_85913721 1.90 ENST00000247655.3
ENST00000509578.1
ENST00000515763.1
cytochrome c oxidase subunit VIIc
chr1_-_151138323 1.89 ENST00000368908.5
LysM, putative peptidoglycan-binding, domain containing 1
chr10_-_94050820 1.89 ENST00000265997.4
cytoplasmic polyadenylation element binding protein 3
chr15_-_55700216 1.88 ENST00000569205.1
cell cycle progression 1
chr3_-_43147549 1.88 ENST00000344697.2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr13_-_30881134 1.88 ENST00000380617.3
ENST00000441394.1
katanin p60 subunit A-like 1
chr19_+_58920102 1.87 ENST00000599238.1
ENST00000322834.7
zinc finger protein 584
chr1_+_12040238 1.85 ENST00000444836.1
ENST00000235329.5
mitofusin 2
chr2_+_202316392 1.85 ENST00000194530.3
ENST00000392249.2
STE20-related kinase adaptor beta
chr12_+_95611569 1.85 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr1_-_150980828 1.85 ENST00000361936.5
ENST00000361738.6
family with sequence similarity 63, member A
chr19_+_56652643 1.83 ENST00000586123.1
zinc finger protein 444
chr10_-_27530997 1.83 ENST00000375901.1
ENST00000412279.1
ENST00000375905.4
acyl-CoA binding domain containing 5
chr4_-_88141755 1.83 ENST00000273963.5
kelch-like family member 8
chr14_+_102430855 1.82 ENST00000360184.4
dynein, cytoplasmic 1, heavy chain 1
chr19_-_36980455 1.82 ENST00000454319.1
ENST00000392170.2
zinc finger protein 566
chr10_+_111985837 1.81 ENST00000393134.1
MAX interactor 1, dimerization protein
chr9_-_26946981 1.80 ENST00000523212.1
phospholipase A2-activating protein
chr3_-_43147431 1.80 ENST00000441964.1
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr1_+_202317815 1.80 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr10_+_111985713 1.79 ENST00000239007.7
MAX interactor 1, dimerization protein
chr20_+_20033158 1.79 ENST00000340348.6
ENST00000377309.2
ENST00000389656.3
ENST00000377306.1
ENST00000245957.5
ENST00000377303.2
ENST00000475466.1
chromosome 20 open reading frame 26
chr4_-_169931393 1.79 ENST00000504480.1
ENST00000306193.3
carbonyl reductase 4
chr1_+_150980889 1.79 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
prune exopolyphosphatase
chr6_+_110501621 1.79 ENST00000368930.1
ENST00000307731.1
cell division cycle 40
chr19_-_36980756 1.78 ENST00000493391.1
zinc finger protein 566
chr6_-_163148700 1.78 ENST00000366894.1
ENST00000338468.3
parkin RBR E3 ubiquitin protein ligase
chr5_+_5422778 1.78 ENST00000296564.7
KIAA0947

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX5_SMARCC2_HCFC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
2.8 8.5 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
2.2 8.8 GO:0009236 cobalamin biosynthetic process(GO:0009236)
1.6 4.9 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
1.4 4.3 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
1.3 5.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
1.2 7.0 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
1.1 3.3 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
1.0 3.1 GO:0042245 RNA repair(GO:0042245)
0.9 2.8 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.9 5.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.9 2.8 GO:0006481 C-terminal protein methylation(GO:0006481)
0.9 3.6 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.9 6.9 GO:0044211 CTP salvage(GO:0044211)
0.8 2.5 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.8 2.5 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.8 13.9 GO:0006108 malate metabolic process(GO:0006108)
0.8 4.9 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.8 2.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.8 6.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.7 3.7 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.7 2.9 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.7 3.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.7 4.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.7 3.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.7 6.6 GO:0051013 microtubule severing(GO:0051013)
0.7 7.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.6 1.9 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.6 1.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.6 4.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.6 1.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.6 1.9 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.6 3.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.6 1.7 GO:0032203 telomere formation via telomerase(GO:0032203)
0.6 1.7 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.6 8.9 GO:0000733 DNA strand renaturation(GO:0000733)
0.6 26.0 GO:0042407 cristae formation(GO:0042407)
0.6 5.5 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.5 3.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.5 3.8 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.5 3.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.5 1.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.5 2.9 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.5 1.4 GO:1905166 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.5 0.5 GO:0036090 cleavage furrow ingression(GO:0036090)
0.5 0.5 GO:0016078 tRNA catabolic process(GO:0016078)
0.5 1.4 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.4 1.7 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.4 0.4 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.4 2.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.4 4.7 GO:0000101 sulfur amino acid transport(GO:0000101)
0.4 1.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.4 3.0 GO:0035624 receptor transactivation(GO:0035624)
0.4 1.7 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.4 3.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4 3.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.4 1.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 8.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.4 1.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.4 0.7 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.4 2.2 GO:0006574 valine catabolic process(GO:0006574)
0.4 1.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.4 1.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.3 1.0 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.3 1.0 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 2.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 1.4 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.3 1.0 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3 1.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 3.9 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.0 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.3 6.3 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.3 5.6 GO:0090168 Golgi reassembly(GO:0090168)
0.3 1.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 4.9 GO:0006449 regulation of translational termination(GO:0006449)
0.3 2.7 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.3 1.5 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.3 3.6 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 0.9 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 0.9 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.3 7.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.3 2.9 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.3 1.7 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.3 0.8 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.3 0.3 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.3 1.4 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.3 1.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 1.9 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3 2.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.3 2.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.3 2.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.3 2.3 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.3 1.8 GO:0051697 protein delipidation(GO:0051697)
0.3 1.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3 2.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.3 7.6 GO:0016180 snRNA processing(GO:0016180)
0.3 1.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.3 1.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 2.3 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.2 1.4 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 2.0 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.9 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 1.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.2 1.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 11.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 1.3 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.2 2.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 2.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 3.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 2.7 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 2.6 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 1.8 GO:0030242 pexophagy(GO:0030242)
0.2 1.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.2 2.8 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.2 3.6 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.2 1.8 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.2 3.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 5.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 3.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.2 2.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 0.5 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 4.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 1.0 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 4.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2 0.5 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.2 1.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 1.3 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.2 19.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 2.6 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 1.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 1.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 2.6 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.2 3.5 GO:0045116 protein neddylation(GO:0045116)
0.2 1.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 1.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.9 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.0 GO:0021997 neural plate axis specification(GO:0021997)
0.1 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 5.8 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.7 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 1.9 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.1 3.1 GO:1901642 nucleoside transmembrane transport(GO:1901642)
0.1 0.5 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 3.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 2.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 2.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 11.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.1 4.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 6.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 2.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 2.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 2.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 4.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 4.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.7 GO:1901661 quinone metabolic process(GO:1901661)
0.1 1.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.5 GO:1903507 negative regulation of nucleic acid-templated transcription(GO:1903507)
0.1 4.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 3.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 1.6 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.1 0.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 6.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.3 GO:1990910 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.1 3.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.1 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 3.5 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 2.9 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 1.0 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 2.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.5 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.3 GO:0040009 regulation of growth rate(GO:0040009) G-quadruplex DNA unwinding(GO:0044806)
0.1 7.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.8 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.3 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 2.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 4.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.4 GO:0039019 pronephric nephron development(GO:0039019)
0.1 4.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 1.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 2.9 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 2.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.1 1.0 GO:1903405 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.1 0.3 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180) RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 0.9 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 1.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.7 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 12.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 1.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 2.9 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.1 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 6.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.1 0.2 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 2.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 3.1 GO:0031648 protein destabilization(GO:0031648)
0.1 3.1 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.7 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.1 4.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 2.2 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.6 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 1.8 GO:0048820 hair follicle maturation(GO:0048820)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.1 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.9 GO:0051597 response to methylmercury(GO:0051597)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.3 GO:0070142 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.1 0.5 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.6 GO:1902855 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184) regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 1.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 1.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.8 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 1.2 GO:0010628 positive regulation of gene expression(GO:0010628)
0.1 1.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 3.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.4 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 4.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.5 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 7.7 GO:0009267 cellular response to starvation(GO:0009267)
0.1 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 3.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 2.0 GO:0006468 protein phosphorylation(GO:0006468)
0.0 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.4 GO:0018126 protein hydroxylation(GO:0018126)
0.0 3.4 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.7 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.5 GO:1905216 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 5.4 GO:0045333 cellular respiration(GO:0045333)
0.0 2.1 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 12.7 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.4 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.0 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.5 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.8 GO:0016246 RNA interference(GO:0016246)
0.0 5.3 GO:0048511 rhythmic process(GO:0048511)
0.0 1.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1903336 intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336)
0.0 0.5 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.6 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 3.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.6 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 1.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.8 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 1.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 1.8 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.0 0.4 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.8 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 1.9 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 2.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 3.3 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 4.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.5 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 2.2 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.9 GO:0034453 microtubule anchoring(GO:0034453)
0.0 10.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 1.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:0061684 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.0 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 2.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 2.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.5 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 2.5 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 10.0 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.7 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.2 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 3.4 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 1.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509) beta-amyloid metabolic process(GO:0050435)
0.0 0.6 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 1.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.1 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.8 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 1.0 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 3.3 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 2.2 GO:0008380 RNA splicing(GO:0008380)
0.0 2.7 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:0006101 citrate metabolic process(GO:0006101)
0.0 0.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 3.0 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 2.4 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.3 GO:0016236 macroautophagy(GO:0016236)
0.0 0.9 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0070423 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.9 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.6 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.6 GO:0007030 Golgi organization(GO:0007030)
0.0 3.6 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.0 0.1 GO:1903772 virus maturation(GO:0019075) regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.9 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.3 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.6 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.2 GO:0007005 mitochondrion organization(GO:0007005)
0.0 0.9 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 52.2 GO:0006351 transcription, DNA-templated(GO:0006351)
0.0 1.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.5 GO:0006952 defense response(GO:0006952)
0.0 1.0 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0015813 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.3 GO:0048278 vesicle docking(GO:0048278)
0.0 0.6 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.1 GO:0051882 mitochondrial depolarization(GO:0051882) regulation of mitochondrial depolarization(GO:0051900)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
1.3 10.4 GO:0061617 MICOS complex(GO:0061617)
1.3 6.5 GO:0009368 endopeptidase Clp complex(GO:0009368)
1.0 4.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.9 9.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.9 4.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.8 2.5 GO:0030689 Noc complex(GO:0030689)
0.7 10.3 GO:0071986 Ragulator complex(GO:0071986)
0.7 5.7 GO:0002177 manchette(GO:0002177)
0.7 2.1 GO:0034515 proteasome storage granule(GO:0034515)
0.7 9.3 GO:0072687 meiotic spindle(GO:0072687)
0.7 2.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 2.5 GO:0071001 U4/U6 snRNP(GO:0071001)
0.6 5.5 GO:0055028 cortical microtubule(GO:0055028)
0.6 3.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.5 8.7 GO:0032039 integrator complex(GO:0032039)
0.5 2.1 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.5 2.5 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.5 1.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.4 1.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.4 2.5 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.4 1.1 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.1 GO:0008623 CHRAC(GO:0008623)
0.4 7.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 2.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 9.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 2.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 1.4 GO:0055087 Ski complex(GO:0055087)
0.3 3.7 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.3 4.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.3 4.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.7 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.3 1.4 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.3 1.9 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 2.5 GO:0070552 BRISC complex(GO:0070552)
0.2 5.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 2.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 3.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 0.7 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.2 5.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 9.6 GO:0034451 centriolar satellite(GO:0034451)
0.2 2.9 GO:0030870 Mre11 complex(GO:0030870)
0.2 0.9 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.2 0.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.2 4.8 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.9 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 1.5 GO:1990130 Iml1 complex(GO:1990130)
0.2 2.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 1.7 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 1.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.6 GO:0071203 WASH complex(GO:0071203)
0.2 4.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.2 8.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 14.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 1.5 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.2 3.6 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 4.8 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.2 5.1 GO:0036020 endolysosome membrane(GO:0036020)
0.2 0.9 GO:0060091 kinocilium(GO:0060091)
0.2 4.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.5 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 2.6 GO:0005869 dynactin complex(GO:0005869)
0.2 1.5 GO:0005683 U7 snRNP(GO:0005683)
0.2 3.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 3.1 GO:0030897 HOPS complex(GO:0030897)
0.2 0.5 GO:0044609 DBIRD complex(GO:0044609)
0.2 5.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 2.0 GO:0005686 U2 snRNP(GO:0005686)
0.2 14.2 GO:0070469 respiratory chain(GO:0070469)
0.1 1.2 GO:0070545 PeBoW complex(GO:0070545)
0.1 5.3 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.4 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 3.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 2.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 4.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 4.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.7 GO:0031201 SNARE complex(GO:0031201)
0.1 1.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 12.3 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.8 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 6.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.5 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 5.8 GO:0016592 mediator complex(GO:0016592)
0.1 2.9 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.7 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.7 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.3 GO:0001940 male pronucleus(GO:0001940)
0.1 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.7 GO:0000815 ESCRT III complex(GO:0000815)
0.1 2.7 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 4.3 GO:0030057 desmosome(GO:0030057)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.1 GO:0072487 MSL complex(GO:0072487)
0.1 4.3 GO:0000421 autophagosome membrane(GO:0000421)
0.1 6.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 0.9 GO:0035859 Seh1-associated complex(GO:0035859)
0.1 3.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 23.7 GO:0043209 myelin sheath(GO:0043209)
0.1 2.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 1.2 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.4 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.1 0.3 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.1 1.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.4 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.6 GO:0005638 lamin filament(GO:0005638)
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.2 GO:0009346 citrate lyase complex(GO:0009346)
0.1 1.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.5 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 2.8 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0070876 SOSS complex(GO:0070876)
0.0 5.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.0 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 5.2 GO:0043195 terminal bouton(GO:0043195)
0.0 16.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.5 GO:0042382 paraspeckles(GO:0042382)
0.0 1.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 2.9 GO:0015030 Cajal body(GO:0015030)
0.0 1.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 5.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 2.1 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 2.6 GO:0044439 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 2.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 1.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 12.5 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 1.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.3 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.5 GO:0005814 centriole(GO:0005814)
0.0 4.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.0 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 8.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.1 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 2.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 7.1 GO:0030016 myofibril(GO:0030016)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 7.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 8.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 3.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 9.7 GO:0016607 nuclear speck(GO:0016607)
0.0 2.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 28.3 GO:0005739 mitochondrion(GO:0005739)
0.0 2.8 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0099568 cytoplasmic region(GO:0099568)
0.0 46.6 GO:0005829 cytosol(GO:0005829)
0.0 0.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 100.0 GO:0005634 nucleus(GO:0005634)
0.0 0.4 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 13.9 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
3.1 9.3 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
2.7 8.2 GO:0031862 prostanoid receptor binding(GO:0031862)
1.9 5.7 GO:0000994 RNA polymerase III core binding(GO:0000994)
1.6 4.9 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
1.4 4.3 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
1.2 4.9 GO:0047708 biotinidase activity(GO:0047708)
1.1 4.6 GO:0016005 phospholipase A2 activator activity(GO:0016005)
1.1 3.3 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
1.0 3.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.9 2.8 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.9 3.7 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.9 2.7 GO:0030626 U12 snRNA binding(GO:0030626)
0.9 2.7 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.8 2.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.8 5.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.8 4.9 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.8 8.7 GO:0004849 uridine kinase activity(GO:0004849)
0.8 3.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.8 3.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.8 5.4 GO:0043532 angiostatin binding(GO:0043532)
0.8 9.8 GO:0031419 cobalamin binding(GO:0031419)
0.6 1.9 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.6 8.9 GO:0036310 annealing helicase activity(GO:0036310)
0.6 2.5 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.6 2.4 GO:0004803 transposase activity(GO:0004803)
0.6 6.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.6 4.8 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 4.7 GO:0048039 ubiquinone binding(GO:0048039)
0.5 3.5 GO:0070728 leucine binding(GO:0070728)
0.5 3.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 1.4 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.5 2.3 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.5 6.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.4 2.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.4 4.7 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.4 3.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.4 3.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.4 1.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.4 1.5 GO:0071209 U7 snRNA binding(GO:0071209)
0.4 2.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.4 2.9 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.4 3.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 12.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 1.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 4.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 1.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.3 2.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 7.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 0.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.3 2.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.3 1.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.3 2.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 0.8 GO:0033149 FFAT motif binding(GO:0033149)
0.3 0.8 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.3 0.8 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.3 3.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 9.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 1.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 4.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 5.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 1.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 1.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 4.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 6.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.4 GO:1903135 cupric ion binding(GO:1903135)
0.2 3.0 GO:0000182 rDNA binding(GO:0000182)
0.2 1.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 8.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 2.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.2 2.1 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 1.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 4.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2 0.6 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.2 5.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.8 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2 5.1 GO:0097602 cullin family protein binding(GO:0097602)
0.2 4.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.4 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.2 0.7 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 0.9 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.2 1.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.1 GO:0097001 ceramide binding(GO:0097001)
0.2 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 3.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 23.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 0.9 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 1.7 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 7.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.2 2.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.2 0.6 GO:0003896 DNA primase activity(GO:0003896)
0.2 1.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 4.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 3.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.6 GO:0034452 dynactin binding(GO:0034452)
0.1 1.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 9.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 9.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 5.4 GO:0045503 dynein light chain binding(GO:0045503)
0.1 0.8 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 4.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 5.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 1.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 1.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 5.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 15.1 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.5 GO:0016595 glutamate binding(GO:0016595)
0.1 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 3.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.9 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 6.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.1 0.7 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 1.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.8 GO:0008483 transaminase activity(GO:0008483)
0.1 2.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.1 24.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.7 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 4.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 3.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.5 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1 0.3 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 3.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 3.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.5 GO:0030515 snoRNA binding(GO:0030515)
0.1 1.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 4.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.5 GO:0051400 BH domain binding(GO:0051400)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 1.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 3.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 5.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 1.4 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 0.7 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 21.2 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 1.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 1.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 4.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 6.9 GO:0019213 deacetylase activity(GO:0019213)
0.1 1.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.2 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 6.4 GO:0017022 myosin binding(GO:0017022)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 1.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 3.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 1.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 4.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 3.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.9 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 2.2 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 2.6 GO:0030507 spectrin binding(GO:0030507)
0.0 2.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.8 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.6 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 1.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 1.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 1.1 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0046870 cadmium ion binding(GO:0046870)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.6 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 1.5 GO:0043621 protein self-association(GO:0043621)
0.0 5.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 2.0 GO:0002039 p53 binding(GO:0002039)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 2.0 GO:0051117 ATPase binding(GO:0051117)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.4 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 41.5 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 2.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 1.0 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 1.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 14.4 GO:0003723 RNA binding(GO:0003723)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 7.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 8.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 9.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 3.3 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 6.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 8.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.6 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 2.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 4.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 4.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 3.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 1.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 7.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.3 7.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.3 1.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 32.2 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.2 18.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 8.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 15.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 4.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 5.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 3.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 5.8 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.2 3.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 3.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 0.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 2.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 2.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 3.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 4.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 2.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 2.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 3.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.1 1.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 6.3 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 1.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 35.0 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 5.9 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.9 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 2.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 4.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 3.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 4.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.9 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 2.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 6.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.9 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides