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Illumina Body Map 2: averaged replicates

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Results for SMAD4

Z-value: 3.46

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Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.9 SMAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg19_v2_chr18_+_48556470_48556640-0.105.9e-01Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_23247030 9.43 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr22_+_22735135 7.28 ENST00000390297.2
IGLV1-44
immunoglobulin lambda variable 1-44
chr22_+_22712087 6.97 ENST00000390294.2
IGLV1-47
immunoglobulin lambda variable 1-47
chr22_+_23063100 6.93 ENST00000390309.2
IGLV3-19
immunoglobulin lambda variable 3-19
chr9_-_34691201 6.87 ENST00000378800.3
ENST00000311925.2
CCL19
chemokine (C-C motif) ligand 19
chr2_-_85890569 6.36 ENST00000494165.1
SFTPB
surfactant protein B
chr10_-_73848531 6.15 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr22_+_22676808 5.80 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr14_-_106878083 5.42 ENST00000390619.2
IGHV4-39
immunoglobulin heavy variable 4-39
chr14_-_106209368 5.31 ENST00000390548.2
ENST00000390549.2
ENST00000390542.2
IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_23029188 5.31 ENST00000390305.2
IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_22681656 5.06 ENST00000390291.2
IGLV1-50
immunoglobulin lambda variable 1-50 (non-functional)
chr14_-_106725723 5.02 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr2_+_90229045 4.91 ENST00000390278.2
IGKV1D-42
immunoglobulin kappa variable 1D-42 (non-functional)
chr10_+_81370689 4.83 ENST00000372308.3
ENST00000398636.3
ENST00000428376.2
ENST00000372313.5
ENST00000419470.2
ENST00000429958.1
ENST00000439264.1
SFTPA1
surfactant protein A1
chr2_-_89513402 4.73 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr19_-_15575369 4.65 ENST00000343625.7
RASAL3
RAS protein activator like 3
chr22_+_22764088 4.64 ENST00000390299.2
IGLV1-40
immunoglobulin lambda variable 1-40
chr1_+_27668505 4.62 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr2_+_89901292 4.59 ENST00000448155.2
IGKV1D-39
immunoglobulin kappa variable 1D-39
chr2_-_89568263 4.13 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr14_-_107131560 4.09 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr2_+_90153696 4.06 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr16_+_32077386 4.05 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr14_-_106816253 4.00 ENST00000390615.2
IGHV3-33
immunoglobulin heavy variable 3-33
chr11_-_118213455 3.99 ENST00000300692.4
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr6_-_32731243 3.95 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr2_-_89417335 3.90 ENST00000490686.1
IGKV1-17
immunoglobulin kappa variable 1-17
chr14_-_106552755 3.87 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr6_-_32731299 3.71 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr9_-_37034028 3.69 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5
paired box 5
chr14_-_106830057 3.68 ENST00000390616.2
IGHV4-34
immunoglobulin heavy variable 4-34
chr14_-_106406090 3.67 ENST00000390593.2
IGHV6-1
immunoglobulin heavy variable 6-1
chr22_+_22786288 3.64 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr2_+_89184868 3.64 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr10_-_73848764 3.63 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr22_+_23077065 3.62 ENST00000390310.2
IGLV2-18
immunoglobulin lambda variable 2-18
chr19_-_44285401 3.62 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_-_106237742 3.56 ENST00000390551.2
IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr2_-_89161064 3.52 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr22_+_22930626 3.46 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr14_-_106668095 3.42 ENST00000390606.2
IGHV3-20
immunoglobulin heavy variable 3-20
chr22_+_22385332 3.37 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr1_+_32827759 3.36 ENST00000373534.3
TSSK3
testis-specific serine kinase 3
chr15_+_81071684 3.34 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
KIAA1199
chr1_-_44482979 3.28 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr22_+_23089870 3.26 ENST00000390311.2
IGLV3-16
immunoglobulin lambda variable 3-16
chr11_-_118213360 3.24 ENST00000529594.1
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr19_-_42636617 3.23 ENST00000529067.1
ENST00000529952.1
ENST00000533720.1
ENST00000389341.5
ENST00000342301.4
POU2F2
POU class 2 homeobox 2
chr2_-_158295915 3.13 ENST00000418920.1
CYTIP
cytohesin 1 interacting protein
chr14_-_106994333 3.11 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr1_+_32739733 3.10 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr2_-_158345462 3.07 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chrX_-_48328631 2.96 ENST00000429543.1
ENST00000317669.5
SLC38A5
solute carrier family 38, member 5
chr2_+_89923550 2.95 ENST00000509129.1
IGKV1D-37
immunoglobulin kappa variable 1D-37 (non-functional)
chr2_-_89459813 2.94 ENST00000390256.2
IGKV6-21
immunoglobulin kappa variable 6-21 (non-functional)
chr1_-_153538292 2.94 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr11_+_117070037 2.88 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr19_-_17958771 2.88 ENST00000534444.1
JAK3
Janus kinase 3
chr1_+_32739714 2.84 ENST00000461712.2
ENST00000373562.3
ENST00000477031.2
ENST00000373557.2
LCK
lymphocyte-specific protein tyrosine kinase
chr16_+_33020496 2.84 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr19_+_17638059 2.83 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr7_-_142247606 2.82 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr17_-_61777459 2.79 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2
LIM domain containing 2
chr6_+_32709119 2.78 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr14_-_91720224 2.76 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr22_+_23241661 2.73 ENST00000390322.2
IGLJ2
immunoglobulin lambda joining 2
chr11_+_60869980 2.72 ENST00000544014.1
CD5
CD5 molecule
chr2_-_89160770 2.61 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr2_+_90458201 2.61 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr2_-_89340242 2.61 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr4_-_74847800 2.60 ENST00000296029.3
PF4
platelet factor 4
chr11_+_60869867 2.60 ENST00000347785.3
CD5
CD5 molecule
chr2_-_89161432 2.57 ENST00000390242.2
IGKJ1
immunoglobulin kappa joining 1
chr7_-_142511084 2.57 ENST00000417977.2
TRBV30
T cell receptor beta variable 30 (gene/pseudogene)
chrX_-_48328551 2.52 ENST00000376876.3
SLC38A5
solute carrier family 38, member 5
chr9_+_136399929 2.50 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr1_-_160681593 2.49 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chr8_+_22019168 2.49 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr2_-_112237835 2.47 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr1_-_31230650 2.47 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr22_+_22569155 2.44 ENST00000390287.2
IGLV10-54
immunoglobulin lambda variable 10-54
chr1_+_159175201 2.44 ENST00000368121.2
DARC
Duffy blood group, atypical chemokine receptor
chr2_-_242801031 2.43 ENST00000334409.5
PDCD1
programmed cell death 1
chr6_+_116937636 2.43 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr7_+_142829162 2.42 ENST00000291009.3
PIP
prolactin-induced protein
chr19_+_17638041 2.40 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr1_+_159141397 2.40 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr10_-_81708854 2.35 ENST00000372292.3
SFTPD
surfactant protein D
chr1_-_207095212 2.34 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr19_-_42636543 2.31 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2
POU class 2 homeobox 2
chr19_-_17958832 2.28 ENST00000458235.1
JAK3
Janus kinase 3
chr19_+_49055332 2.25 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr14_-_106330458 2.25 ENST00000461719.1
IGHJ4
immunoglobulin heavy joining 4
chr2_-_85895295 2.19 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chr16_+_2880369 2.19 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr20_+_57766075 2.16 ENST00000371030.2
ZNF831
zinc finger protein 831
chr15_-_20193370 2.14 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr22_+_23213658 2.13 ENST00000390318.2
IGLV4-3
immunoglobulin lambda variable 4-3
chr17_+_41003166 2.11 ENST00000308423.2
AOC3
amine oxidase, copper containing 3
chr2_+_177025619 2.11 ENST00000410016.1
HOXD3
homeobox D3
chr7_+_142028105 2.10 ENST00000390353.2
TRBV6-1
T cell receptor beta variable 6-1
chr19_-_43032532 2.05 ENST00000403461.1
ENST00000352591.5
ENST00000358394.3
ENST00000403444.3
ENST00000308072.4
ENST00000599389.1
ENST00000351134.3
ENST00000161559.6
CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr22_+_22707260 2.05 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr8_+_104383728 2.05 ENST00000330295.5
CTHRC1
collagen triple helix repeat containing 1
chr8_+_104383759 2.04 ENST00000415886.2
CTHRC1
collagen triple helix repeat containing 1
chr15_-_74726283 2.03 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr10_-_73848086 2.02 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr14_+_22309368 2.02 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr19_-_14629224 2.02 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr14_+_22320634 2.00 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr16_-_33647696 1.98 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr12_-_57871825 1.98 ENST00000548139.1
ARHGAP9
Rho GTPase activating protein 9
chr12_-_57871853 1.97 ENST00000549602.1
ENST00000430041.2
ARHGAP9
Rho GTPase activating protein 9
chr14_+_22771851 1.97 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr4_+_71384257 1.96 ENST00000339336.4
AMTN
amelotin
chr19_-_11688447 1.96 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr11_-_118213331 1.96 ENST00000392884.2
CD3D
CD3d molecule, delta (CD3-TCR complex)
chr15_+_49715293 1.93 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr11_-_107729887 1.93 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr14_+_22362613 1.92 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chr12_-_15103621 1.91 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_-_9913489 1.91 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr1_-_207095324 1.90 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr1_+_26485511 1.90 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr19_-_41859814 1.90 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr1_+_26869597 1.89 ENST00000530003.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_+_11649532 1.89 ENST00000252456.2
ENST00000592923.1
ENST00000535659.2
CNN1
calponin 1, basic, smooth muscle
chr5_-_121413974 1.89 ENST00000231004.4
LOX
lysyl oxidase
chr15_+_49715449 1.89 ENST00000560979.1
FGF7
fibroblast growth factor 7
chr19_-_54784353 1.88 ENST00000391746.1
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr7_+_142448053 1.88 ENST00000422143.2
TRBV29-1
T cell receptor beta variable 29-1
chr2_-_85108164 1.88 ENST00000409520.2
TRABD2A
TraB domain containing 2A
chr1_+_203734296 1.87 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr2_-_85108363 1.87 ENST00000335459.5
TRABD2A
TraB domain containing 2A
chr14_+_22739823 1.85 ENST00000390464.2
TRAV38-1
T cell receptor alpha variable 38-1
chr1_-_153522562 1.85 ENST00000368714.1
S100A4
S100 calcium binding protein A4
chr19_-_11688500 1.84 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr13_+_102104952 1.83 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_-_139727118 1.83 ENST00000484111.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr16_+_9056563 1.83 ENST00000564485.1
RP11-77H9.8
RP11-77H9.8
chr8_+_104384616 1.82 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr1_-_32827682 1.79 ENST00000432622.1
FAM229A
family with sequence similarity 229, member A
chr19_+_46171464 1.79 ENST00000590918.1
ENST00000263281.3
ENST00000304207.8
GIPR
gastric inhibitory polypeptide receptor
chr1_-_202129704 1.77 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_54784937 1.77 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr12_-_53594227 1.75 ENST00000550743.2
ITGB7
integrin, beta 7
chr12_-_7281469 1.74 ENST00000542370.1
ENST00000266560.3
RBP5
retinol binding protein 5, cellular
chr1_-_59249732 1.74 ENST00000371222.2
JUN
jun proto-oncogene
chr1_-_160492994 1.73 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr4_-_13546632 1.71 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr11_+_60739115 1.71 ENST00000344028.5
ENST00000346437.4
CD6
CD6 molecule
chr12_-_15104040 1.71 ENST00000541644.1
ENST00000545895.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_87769459 1.70 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr4_+_25657444 1.70 ENST00000504570.1
ENST00000382051.3
SLC34A2
solute carrier family 34 (type II sodium/phosphate contransporter), member 2
chr12_-_57872336 1.69 ENST00000552066.1
ARHGAP9
Rho GTPase activating protein 9
chr19_+_49838653 1.68 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chrX_-_70326455 1.68 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr9_-_117150243 1.68 ENST00000374088.3
AKNA
AT-hook transcription factor
chr9_-_113342160 1.67 ENST00000401783.2
ENST00000374461.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr19_-_54824344 1.67 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr19_-_51529849 1.66 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
KLK11
kallikrein-related peptidase 11
chr9_-_113341985 1.64 ENST00000374469.1
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr19_-_47287990 1.64 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr19_-_54984354 1.64 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr1_-_157670647 1.64 ENST00000368184.3
FCRL3
Fc receptor-like 3
chr2_-_158345341 1.63 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr4_+_74718906 1.61 ENST00000226524.3
PF4V1
platelet factor 4 variant 1
chr15_+_81591757 1.60 ENST00000558332.1
IL16
interleukin 16
chr12_-_48213568 1.59 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7
histone deacetylase 7
chr11_-_107729287 1.59 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr1_-_44497024 1.58 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr1_-_160832642 1.57 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr12_-_11463353 1.57 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
PRB4
proline-rich protein BstNI subfamily 4
chr11_+_45943169 1.57 ENST00000529052.1
ENST00000531526.1
GYLTL1B
glycosyltransferase-like 1B
chr19_+_7413835 1.57 ENST00000576789.1
CTB-133G6.1
CTB-133G6.1
chrX_+_48542168 1.56 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr1_-_153538011 1.56 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr1_-_161168834 1.56 ENST00000367995.3
ENST00000367996.5
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr1_-_160832490 1.55 ENST00000322302.7
ENST00000368033.3
CD244
CD244 molecule, natural killer cell receptor 2B4
chr12_+_54384370 1.55 ENST00000504315.1
HOXC6
homeobox C6
chr11_+_67171548 1.53 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr19_+_41949054 1.53 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chr2_+_30454390 1.52 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr6_-_32908765 1.51 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr7_+_94023873 1.50 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chrX_-_119445306 1.49 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr1_+_27669719 1.49 ENST00000473280.1
SYTL1
synaptotagmin-like 1
chr12_+_52445191 1.48 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr4_+_166794383 1.48 ENST00000061240.2
ENST00000507499.1
TLL1
tolloid-like 1
chr13_+_102104980 1.48 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_+_26348259 1.48 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr16_+_2880157 1.47 ENST00000382280.3
ZG16B
zymogen granule protein 16B
chr12_-_11422739 1.47 ENST00000279573.7
PRB3
proline-rich protein BstNI subfamily 3
chr12_+_104982622 1.46 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr5_-_168727786 1.45 ENST00000332966.8
SLIT3
slit homolog 3 (Drosophila)
chr11_-_64612041 1.44 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr5_-_168728103 1.44 ENST00000519560.1
SLIT3
slit homolog 3 (Drosophila)
chr12_+_54519842 1.44 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chr7_-_45018686 1.43 ENST00000258787.7
MYO1G
myosin IG

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 6.9 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
2.1 6.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
1.7 5.2 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
1.3 1.3 GO:1902214 regulation of interleukin-4-mediated signaling pathway(GO:1902214)
1.3 3.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
1.2 4.9 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
1.0 3.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
1.0 7.8 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.9 3.8 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.9 2.6 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.8 2.4 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.8 2.4 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.8 3.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.8 4.7 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.8 2.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.7 4.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.7 5.5 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.7 2.1 GO:0043317 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.6 109.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.6 1.2 GO:0070662 mast cell proliferation(GO:0070662)
0.6 9.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.6 2.4 GO:0006218 uridine catabolic process(GO:0006218)
0.6 1.7 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.6 2.2 GO:0000103 sulfate assimilation(GO:0000103)
0.5 4.4 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 0.5 GO:0030908 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.5 3.6 GO:0071461 cellular response to redox state(GO:0071461)
0.5 12.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.5 0.5 GO:0071231 cellular response to folic acid(GO:0071231)
0.5 2.0 GO:0030185 nitric oxide transport(GO:0030185)
0.5 1.5 GO:0033037 polysaccharide localization(GO:0033037)
0.5 1.0 GO:0046102 inosine metabolic process(GO:0046102)
0.5 1.4 GO:0043315 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.5 1.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 3.6 GO:2000035 regulation of stem cell division(GO:2000035)
0.4 2.2 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.4 1.3 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.4 3.5 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.4 2.6 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.4 3.4 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 9.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 6.4 GO:0015816 glycine transport(GO:0015816)
0.4 2.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 2.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 1.2 GO:0090273 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.4 1.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.4 2.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4 1.6 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.4 1.2 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.4 1.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 1.5 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.4 1.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.3 2.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) abortive mitotic cell cycle(GO:0033277)
0.3 2.4 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.3 1.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.0 GO:0086044 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.3 0.6 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.3 0.9 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.3 0.9 GO:2000452 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) positive regulation of necroptotic process(GO:0060545) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.3 0.9 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.3 2.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 0.9 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.3 0.9 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.3 4.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.2 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.3 2.1 GO:0071462 cellular response to water stimulus(GO:0071462)
0.3 4.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.3 0.3 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.3 2.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 2.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.9 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.3 0.9 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.3 1.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.3 2.0 GO:0014028 notochord formation(GO:0014028)
0.3 1.1 GO:0019417 sulfur oxidation(GO:0019417)
0.3 0.5 GO:0061010 gall bladder development(GO:0061010)
0.3 1.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 0.8 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.3 1.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3 0.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.3 2.3 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.3 2.0 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.3 54.6 GO:0002377 immunoglobulin production(GO:0002377)
0.2 0.7 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 1.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 1.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.2 0.7 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.2 1.0 GO:0061743 motor learning(GO:0061743)
0.2 2.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.2 0.7 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.2 0.9 GO:0002432 granuloma formation(GO:0002432)
0.2 2.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 0.7 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.2 0.7 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.2 0.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.9 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.8 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.2 1.0 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488)
0.2 1.2 GO:0042335 cuticle development(GO:0042335)
0.2 4.2 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.2 1.8 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2 0.8 GO:0001878 response to yeast(GO:0001878)
0.2 2.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.5 GO:0050894 determination of affect(GO:0050894)
0.2 22.4 GO:0031295 T cell costimulation(GO:0031295)
0.2 4.9 GO:0045109 intermediate filament organization(GO:0045109)
0.2 2.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 1.0 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 0.8 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.2 0.3 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2 0.5 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 3.7 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 4.3 GO:0001771 immunological synapse formation(GO:0001771)
0.2 1.3 GO:0070383 DNA cytosine deamination(GO:0070383)
0.2 1.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 1.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2 0.9 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.2 1.9 GO:0072501 cellular divalent inorganic anion homeostasis(GO:0072501)
0.2 0.6 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.2 2.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.6 GO:0060018 astrocyte fate commitment(GO:0060018)
0.2 0.6 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.6 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.5 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 1.4 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.9 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.1 0.4 GO:0051714 regulation of cytolysis in other organism(GO:0051710) positive regulation of cytolysis in other organism(GO:0051714)
0.1 1.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 1.9 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 1.7 GO:0001787 natural killer cell proliferation(GO:0001787)
0.1 2.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.7 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.1 2.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 14.5 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.1 1.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.4 GO:0007412 axon target recognition(GO:0007412)
0.1 0.4 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.7 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 0.5 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 1.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.3 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.1 0.5 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.7 GO:0010165 response to X-ray(GO:0010165)
0.1 2.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 0.6 GO:0010958 regulation of amino acid import(GO:0010958) L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) negative regulation of mitotic cell cycle DNA replication(GO:1903464) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.6 GO:0070384 Harderian gland development(GO:0070384)
0.1 0.5 GO:0061626 BMP signaling pathway involved in heart development(GO:0061312) pharyngeal arch artery morphogenesis(GO:0061626)
0.1 0.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.9 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 1.0 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 2.5 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 0.8 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.6 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 1.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0033082 extrathymic T cell differentiation(GO:0033078) regulation of extrathymic T cell differentiation(GO:0033082)
0.1 0.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 1.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.3 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.1 0.7 GO:0021699 hindbrain maturation(GO:0021578) cerebellum maturation(GO:0021590) central nervous system maturation(GO:0021626) cerebellar cortex maturation(GO:0021699)
0.1 1.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.4 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.1 GO:0032264 IMP salvage(GO:0032264)
0.1 3.1 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.3 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0003169 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.4 GO:0010446 response to alkaline pH(GO:0010446)
0.1 7.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 1.0 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.4 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.6 GO:1905066 arterial endothelial cell fate commitment(GO:0060844) positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 0.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.1 1.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.3 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.1 1.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.6 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 0.7 GO:2001199 regulation of dendritic cell differentiation(GO:2001198) negative regulation of dendritic cell differentiation(GO:2001199)
0.1 0.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 1.0 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807)
0.1 0.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.5 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.5 GO:0030002 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
0.1 1.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.9 GO:0072321 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) chaperone-mediated protein transport(GO:0072321)
0.1 0.4 GO:0050893 sensory processing(GO:0050893)
0.1 0.4 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.3 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.7 GO:0048680 positive regulation of axon regeneration(GO:0048680)
0.1 1.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.9 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.8 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.1 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.5 GO:0032328 alanine transport(GO:0032328)
0.1 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.6 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 1.5 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.1 1.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.6 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 1.0 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.1 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.3 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 1.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.3 GO:0043585 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 3.4 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.7 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 0.5 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.0 4.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.9 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 1.1 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0048631 negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.5 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.8 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 1.1 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.2 GO:1900111 regulation of histone H3-K9 dimethylation(GO:1900109) positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.3 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.5 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.2 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) regulation of aldosterone secretion(GO:2000858)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 1.5 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 3.2 GO:0031016 pancreas development(GO:0031016)
0.0 1.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.8 GO:0072678 T cell migration(GO:0072678)
0.0 0.2 GO:0071839 apoptotic process in bone marrow(GO:0071839)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.7 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 2.1 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.9 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 2.9 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.1 GO:1990736 positive regulation of regulation of vascular smooth muscle cell membrane depolarization(GO:1904199) regulation of vascular smooth muscle cell membrane depolarization(GO:1990736)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.5 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 1.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.6 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.6 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:1901739 regulation of myoblast fusion(GO:1901739) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:1903859 dendrite extension(GO:0097484) regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 1.0 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.5 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0045076 regulation of interleukin-2 biosynthetic process(GO:0045076)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 1.7 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 1.3 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.8 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.9 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 1.6 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.8 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 1.6 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 1.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.3 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 2.5 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 1.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.5 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 1.0 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.6 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 1.0 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 1.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0030282 bone mineralization(GO:0030282)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.3 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.2 GO:0014029 nucleolus organization(GO:0007000) neural crest formation(GO:0014029)
0.0 0.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 1.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0070228 regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.8 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.0 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 1.3 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.8 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 11.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.9 2.6 GO:0097679 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.9 11.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.8 2.4 GO:0001534 radial spoke(GO:0001534)
0.7 15.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.6 34.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.5 1.5 GO:0005584 collagen type I trimer(GO:0005584)
0.4 1.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 1.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 1.5 GO:0005607 laminin-2 complex(GO:0005607)
0.4 1.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 1.4 GO:0031523 Myb complex(GO:0031523)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 7.5 GO:0042101 T cell receptor complex(GO:0042101)
0.3 1.9 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 2.9 GO:0071953 elastic fiber(GO:0071953)
0.3 0.8 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 2.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.8 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2 1.7 GO:0035976 AP1 complex(GO:0035976)
0.2 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.6 GO:0071821 FANCM-MHF complex(GO:0071821)
0.2 3.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.2 0.7 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.3 GO:0071437 invadopodium(GO:0071437)
0.2 0.3 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 5.6 GO:0031528 microvillus membrane(GO:0031528)
0.2 9.7 GO:0001772 immunological synapse(GO:0001772)
0.2 0.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 22.6 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.1 1.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 3.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 2.6 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 21.8 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0032010 phagolysosome(GO:0032010)
0.1 2.4 GO:0005605 basal lamina(GO:0005605)
0.1 1.1 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.1 GO:0097526 spliceosomal tri-snRNP complex(GO:0097526)
0.1 0.7 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 2.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 1.0 GO:0044853 plasma membrane raft(GO:0044853)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.4 GO:0031905 early endosome lumen(GO:0031905)
0.1 9.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 3.9 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.8 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 5.9 GO:0005902 microvillus(GO:0005902)
0.1 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.2 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 1.3 GO:0097342 ripoptosome(GO:0097342)
0.1 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 1.7 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.4 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.5 GO:0030478 actin cap(GO:0030478)
0.0 1.5 GO:0042629 mast cell granule(GO:0042629)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 6.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 8.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 12.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 72.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.1 GO:0001533 cornified envelope(GO:0001533)
0.0 2.5 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 6.7 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 8.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 1.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 2.3 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 6.3 GO:0005769 early endosome(GO:0005769)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.7 GO:0034774 secretory granule lumen(GO:0034774)
0.0 0.3 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.6 6.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
1.0 16.8 GO:0032395 MHC class II receptor activity(GO:0032395)
0.8 3.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.7 6.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.7 5.5 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.7 2.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 1.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.6 3.6 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.6 6.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.6 2.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.6 2.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.6 145.9 GO:0003823 antigen binding(GO:0003823)
0.6 2.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.5 4.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.5 2.4 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.5 4.6 GO:0048495 Roundabout binding(GO:0048495)
0.5 2.3 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.4 1.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.4 3.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 1.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.4 1.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.4 3.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 1.2 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.4 11.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 2.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.3 1.0 GO:0086078 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.3 2.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 2.2 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.3 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.3 1.9 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 8.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.3 1.5 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.3 4.7 GO:0019864 IgG binding(GO:0019864)
0.3 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.6 GO:0050436 microfibril binding(GO:0050436)
0.3 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3 0.8 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.3 10.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 1.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.7 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 1.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 1.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 1.0 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0005055 laminin receptor activity(GO:0005055)
0.2 1.8 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.2 1.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 1.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 3.7 GO:0008199 ferric iron binding(GO:0008199)
0.2 1.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 3.0 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 0.5 GO:0031877 somatostatin receptor binding(GO:0031877)
0.2 2.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 1.8 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 3.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 0.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.2 0.8 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.8 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.2 0.6 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 1.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.5 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 1.7 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.9 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.1 0.4 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 1.3 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.4 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 1.0 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.4 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 1.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 2.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.9 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 1.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 2.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0019862 IgA binding(GO:0019862)
0.1 1.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0035326 enhancer binding(GO:0035326)
0.1 0.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 2.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 4.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.7 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 7.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.1 0.6 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 3.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.1 0.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 1.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.9 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 6.2 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.4 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.3 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.1 0.5 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.6 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.5 GO:0005119 smoothened binding(GO:0005119)
0.1 0.9 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 2.3 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.1 GO:0031005 filamin binding(GO:0031005)
0.1 6.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.8 GO:0048018 receptor agonist activity(GO:0048018)
0.1 1.0 GO:0017022 myosin binding(GO:0017022)
0.1 3.0 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 1.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 3.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 2.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0036310 annealing helicase activity(GO:0036310)
0.1 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004) neurotrophin receptor activity(GO:0005030)
0.1 1.0 GO:0019841 retinol binding(GO:0019841)
0.1 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 1.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 1.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.3 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 13.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 1.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.5 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.5 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.8 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 2.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 10.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.0 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 2.6 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.2 3.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 13.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 12.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 4.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 5.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 4.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 18.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.8 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 0.7 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 11.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 3.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.2 PID BCR 5PATHWAY BCR signaling pathway
0.1 22.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.6 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 1.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 7.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 6.9 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 1.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 14.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 4.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 3.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 4.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 5.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 21.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.4 5.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.3 4.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 4.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 6.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 12.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 5.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 8.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 3.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 10.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.2 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 2.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 6.0 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 2.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 5.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 2.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 2.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 3.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 3.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 4.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0 0.2 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 3.6 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 2.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling