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Illumina Body Map 2: averaged replicates

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Results for SOX10_SOX15

Z-value: 1.79

Motif logo

Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
ENSG00000100146.12 SOX10
ENSG00000129194.3 SOX15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX10hg19_v2_chr22_-_38380543_38380569-0.392.9e-02Click!
SOX15hg19_v2_chr17_-_7493390_7493488-0.383.2e-02Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_111260856 7.56 ENST00000352690.4
CD96
CD96 molecule
chr3_+_111260954 7.33 ENST00000283285.5
CD96
CD96 molecule
chr3_+_111260980 6.80 ENST00000438817.2
CD96
CD96 molecule
chr18_-_74728998 6.15 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr1_-_200992827 5.90 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr4_-_109090106 4.92 ENST00000379951.2
LEF1
lymphoid enhancer-binding factor 1
chr11_+_128563652 4.56 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_128222103 4.20 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chrX_+_12993202 4.16 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr4_+_154387480 3.66 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr13_-_41593425 3.58 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr5_-_65018834 3.54 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chrX_+_12993336 3.53 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr9_-_74383302 3.52 ENST00000377066.5
TMEM2
transmembrane protein 2
chr5_-_157002775 3.47 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr5_-_157002749 3.45 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr8_+_61822605 3.29 ENST00000526936.1
AC022182.1
AC022182.1
chr4_-_164534657 3.20 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr4_-_109089573 3.16 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr14_-_91884150 3.10 ENST00000553403.1
CCDC88C
coiled-coil domain containing 88C
chr10_+_11206925 2.84 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2
CUGBP, Elav-like family member 2
chr6_+_114178512 2.77 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_+_11751748 2.71 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr5_-_65017921 2.67 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr8_-_80993010 2.65 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr14_+_22309368 2.65 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr14_-_91884115 2.61 ENST00000389857.6
CCDC88C
coiled-coil domain containing 88C
chr9_-_123476612 2.55 ENST00000426959.1
MEGF9
multiple EGF-like-domains 9
chr6_-_30654977 2.54 ENST00000399199.3
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr11_+_36317830 2.49 ENST00000530639.1
PRR5L
proline rich 5 like
chr10_+_11207088 2.46 ENST00000608830.1
CELF2
CUGBP, Elav-like family member 2
chr17_+_75447326 2.44 ENST00000591088.1
SEPT9
septin 9
chr15_-_52043722 2.40 ENST00000454181.2
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chrX_+_37639302 2.32 ENST00000545017.1
ENST00000536160.1
CYBB
cytochrome b-245, beta polypeptide
chr10_-_99030395 2.29 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr12_+_8666126 2.27 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr6_-_130536774 2.26 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr1_-_154155675 2.25 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr22_+_27053422 2.24 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr12_-_42631529 2.24 ENST00000548917.1
YAF2
YY1 associated factor 2
chr12_-_45269769 2.23 ENST00000548826.1
NELL2
NEL-like 2 (chicken)
chr3_+_39509163 2.20 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP
myelin-associated oligodendrocyte basic protein
chr12_-_45270077 2.19 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2
NEL-like 2 (chicken)
chr17_-_9939854 2.15 ENST00000584146.2
GAS7
growth arrest-specific 7
chr2_+_232573208 2.15 ENST00000409115.3
PTMA
prothymosin, alpha
chr21_+_30672433 2.14 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr5_+_149865838 2.12 ENST00000519157.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_+_39509070 2.11 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
MOBP
myelin-associated oligodendrocyte basic protein
chr7_+_29234028 2.10 ENST00000222792.6
CHN2
chimerin 2
chr12_-_45270151 2.09 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr4_-_176733377 2.08 ENST00000505375.1
GPM6A
glycoprotein M6A
chr20_-_4804244 2.07 ENST00000379400.3
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr16_-_4852915 2.06 ENST00000322048.7
ROGDI
rogdi homolog (Drosophila)
chr5_-_146435572 2.03 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr2_-_158182410 2.03 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr12_-_109027643 2.01 ENST00000388962.3
ENST00000550948.1
SELPLG
selectin P ligand
chr17_+_36861735 2.01 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_232573222 2.00 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr2_+_120517174 1.99 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr5_-_175964366 1.98 ENST00000274811.4
RNF44
ring finger protein 44
chr5_+_147258266 1.91 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chrX_+_129305623 1.90 ENST00000257017.4
RAB33A
RAB33A, member RAS oncogene family
chr17_-_7297519 1.88 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr7_+_50344289 1.88 ENST00000413698.1
ENST00000359197.5
ENST00000331340.3
ENST00000357364.4
ENST00000343574.5
ENST00000349824.4
ENST00000346667.4
ENST00000440768.2
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr17_-_7297833 1.87 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr17_+_75283973 1.87 ENST00000431235.2
ENST00000449803.2
SEPT9
septin 9
chr22_+_27053567 1.83 ENST00000449717.1
ENST00000453023.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chrY_+_15016013 1.82 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr5_-_146435694 1.80 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr17_-_9940058 1.80 ENST00000585266.1
GAS7
growth arrest-specific 7
chrX_+_37639264 1.80 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr12_-_24715307 1.79 ENST00000538905.1
RP11-444D3.1
RP11-444D3.1
chr1_+_40840320 1.79 ENST00000372708.1
SMAP2
small ArfGAP2
chr5_-_39424961 1.77 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr2_+_89184868 1.76 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr15_-_70388943 1.76 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr14_+_22320634 1.74 ENST00000390435.1
TRAV8-3
T cell receptor alpha variable 8-3
chr3_-_71353892 1.72 ENST00000484350.1
FOXP1
forkhead box P1
chr3_-_18466026 1.67 ENST00000417717.2
SATB1
SATB homeobox 1
chr6_-_64029879 1.66 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr20_+_48884002 1.64 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr17_-_76713100 1.61 ENST00000585509.1
CYTH1
cytohesin 1
chr2_-_158182322 1.61 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr6_-_91006461 1.60 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr5_+_149865377 1.60 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_-_9939935 1.60 ENST00000580043.1
GAS7
growth arrest-specific 7
chr4_+_26322987 1.60 ENST00000505958.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr13_-_99959641 1.59 ENST00000376414.4
GPR183
G protein-coupled receptor 183
chrY_+_15815447 1.56 ENST00000284856.3
TMSB4Y
thymosin beta 4, Y-linked
chr11_+_67007518 1.55 ENST00000530342.1
ENST00000308783.5
KDM2A
lysine (K)-specific demethylase 2A
chr7_+_29234101 1.55 ENST00000435288.2
CHN2
chimerin 2
chr5_-_146435501 1.52 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr17_+_37809333 1.52 ENST00000443521.1
STARD3
StAR-related lipid transfer (START) domain containing 3
chr1_+_66797687 1.52 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_+_118955635 1.51 ENST00000433996.2
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr9_-_35115836 1.51 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
FAM214B
family with sequence similarity 214, member B
chr17_-_49124230 1.51 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr22_+_37959647 1.49 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr7_+_31726822 1.48 ENST00000409146.3
PPP1R17
protein phosphatase 1, regulatory subunit 17
chr20_-_39317868 1.47 ENST00000373313.2
MAFB
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr10_-_14613968 1.44 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr7_-_105926058 1.44 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr10_+_114710211 1.44 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_151102529 1.43 ENST00000302632.3
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr3_+_152879985 1.43 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr20_+_35202909 1.42 ENST00000558530.1
ENST00000558028.1
ENST00000560025.1
TGIF2-C20orf24
TGIF2
TGIF2-C20orf24 readthrough
TGFB-induced factor homeobox 2
chr3_+_151986709 1.40 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr4_-_140477910 1.39 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr10_+_99079008 1.38 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr22_+_19710468 1.37 ENST00000366425.3
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr12_-_12674032 1.36 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr1_+_200993071 1.36 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr9_-_130712995 1.35 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr12_+_104359641 1.35 ENST00000537100.1
TDG
thymine-DNA glycosylase
chrX_-_142722897 1.34 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr9_-_123476719 1.33 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr14_+_22984601 1.33 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr12_+_15475462 1.33 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_+_66458072 1.31 ENST00000423207.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_+_32288725 1.30 ENST00000315285.3
SPAST
spastin
chr13_+_111767650 1.30 ENST00000449979.1
ENST00000370623.3
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr10_-_14614311 1.30 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr10_-_14614122 1.29 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr14_+_77228532 1.28 ENST00000167106.4
ENST00000554237.1
VASH1
vasohibin 1
chr2_-_166060382 1.27 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr1_-_204436344 1.26 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr2_-_166060552 1.26 ENST00000283254.7
ENST00000453007.1
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr15_-_52944231 1.24 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr13_+_78315466 1.24 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr18_+_72201829 1.23 ENST00000582365.1
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr4_+_106067943 1.23 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
TET2
tet methylcytosine dioxygenase 2
chr3_-_62359180 1.23 ENST00000283268.3
FEZF2
FEZ family zinc finger 2
chr15_+_52043813 1.23 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr15_+_81293254 1.22 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr10_-_14614095 1.22 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr3_+_141105235 1.22 ENST00000503809.1
ZBTB38
zinc finger and BTB domain containing 38
chr2_-_37501692 1.20 ENST00000443977.1
PRKD3
protein kinase D3
chr13_+_78315348 1.20 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chr10_-_14646388 1.19 ENST00000468747.1
ENST00000378467.4
FAM107B
family with sequence similarity 107, member B
chr8_-_133071627 1.18 ENST00000443356.2
ENST00000603859.1
ENST00000254627.3
OC90
OC90
Otoconin-90
otoconin 90
chr2_-_37899323 1.18 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr14_+_23011142 1.18 ENST00000390533.1
TRAJ4
T cell receptor alpha joining 4
chr12_-_49582593 1.17 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr13_+_78315528 1.17 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr10_-_99094458 1.17 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr3_-_69590486 1.16 ENST00000497880.1
FRMD4B
FERM domain containing 4B
chr1_+_36621174 1.15 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr1_-_226926864 1.15 ENST00000429204.1
ENST00000366784.1
ITPKB
inositol-trisphosphate 3-kinase B
chr2_+_32288657 1.14 ENST00000345662.1
SPAST
spastin
chr17_-_18950310 1.14 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr2_-_166060571 1.14 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr12_-_49504449 1.13 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr14_-_67981916 1.12 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr22_+_22453093 1.12 ENST00000390283.2
IGLV8-61
immunoglobulin lambda variable 8-61
chr11_+_35198118 1.11 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44
CD44 molecule (Indian blood group)
chr14_-_57272366 1.10 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2
orthodenticle homeobox 2
chr18_+_72201664 1.09 ENST00000358821.3
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr12_-_31477072 1.09 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr15_+_52043758 1.09 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr2_-_158182105 1.08 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr8_-_20040638 1.08 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr11_-_130184555 1.08 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr6_-_127840021 1.06 ENST00000465909.2
SOGA3
SOGA family member 3
chr4_-_123377880 1.05 ENST00000226730.4
IL2
interleukin 2
chr9_+_137218362 1.04 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr13_+_78315295 1.04 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr1_-_32801825 1.04 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr15_+_75074915 1.04 ENST00000567123.1
ENST00000569462.1
CSK
c-src tyrosine kinase
chr12_-_90049878 1.03 ENST00000359142.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr4_+_146403912 1.03 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1
SMAD family member 1
chr4_+_118955500 1.03 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr7_+_114562909 1.02 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr11_-_130184470 1.01 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chrX_-_19689106 1.01 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr17_-_73389737 1.01 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr22_+_27053545 0.98 ENST00000458302.1
ENST00000419237.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr2_+_149402989 0.98 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr18_-_74207146 0.97 ENST00000443185.2
ZNF516
zinc finger protein 516
chr1_+_29241027 0.97 ENST00000373797.1
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr5_-_150521192 0.97 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr8_-_121824374 0.96 ENST00000517992.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr9_-_130517309 0.96 ENST00000414380.1
SH2D3C
SH2 domain containing 3C
chr6_+_108881012 0.96 ENST00000343882.6
FOXO3
forkhead box O3
chr6_-_134861089 0.95 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr10_-_14596140 0.94 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr18_-_53019208 0.94 ENST00000562607.1
TCF4
transcription factor 4
chr22_-_39150947 0.93 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2
Sad1 and UNC84 domain containing 2
chr12_-_90049828 0.92 ENST00000261173.2
ENST00000348959.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr3_+_133118839 0.92 ENST00000302334.2
BFSP2
beaded filament structural protein 2, phakinin
chr12_-_14133053 0.92 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chrX_-_110655306 0.91 ENST00000371993.2
DCX
doublecortin
chr6_+_64282447 0.89 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_+_29815013 0.89 ENST00000394744.2
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr2_+_162272605 0.89 ENST00000389554.3
TBR1
T-box, brain, 1
chr11_-_102323489 0.89 ENST00000361236.3
TMEM123
transmembrane protein 123
chr22_-_21984282 0.89 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr8_-_116681686 0.89 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr15_-_67439270 0.88 ENST00000558463.1
RP11-342M21.2
Uncharacterized protein
chr17_+_73452545 0.88 ENST00000314256.7
KIAA0195
KIAA0195
chr20_-_23066953 0.87 ENST00000246006.4
CD93
CD93 molecule

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
7.2 21.7 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
1.2 8.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.0 6.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.0 7.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.8 4.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.7 2.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.6 3.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.5 1.6 GO:0035700 astrocyte chemotaxis(GO:0035700) regulation of astrocyte chemotaxis(GO:2000458)
0.5 2.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 2.0 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.5 1.9 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.5 0.5 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.4 1.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 6.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 1.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.3 1.4 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.3 6.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 2.9 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.3 1.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 0.9 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.3 1.8 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 1.7 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.3 1.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.3 1.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.3 2.1 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 2.4 GO:0051013 microtubule severing(GO:0051013)
0.2 0.7 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.2 3.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 1.7 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2 2.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.2 2.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.4 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 1.7 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 4.2 GO:0043383 negative T cell selection(GO:0043383)
0.2 1.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.2 5.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.7 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.2 0.5 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.2 3.0 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.1 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 1.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 4.6 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 1.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.9 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 2.1 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.6 GO:0010157 response to chlorate(GO:0010157)
0.1 4.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 1.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 2.0 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 1.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 3.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 7.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 0.5 GO:0003292 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.1 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.3 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.9 GO:0099515 actin filament-based transport(GO:0099515)
0.1 3.5 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.1 0.3 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 0.6 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.4 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 2.1 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.1 0.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 5.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 6.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 1.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.4 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.6 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 1.0 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.9 GO:0070777 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 2.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) negative regulation of chromatin silencing(GO:0031936) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.4 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.1 0.6 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 1.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 1.4 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.3 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 1.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 2.9 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 2.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 1.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 5.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 1.3 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.7 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.3 GO:0001736 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 1.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.8 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.7 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.9 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.4 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 1.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.4 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.6 GO:0045581 negative regulation of T cell differentiation(GO:0045581)
0.0 0.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.8 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.8 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.1 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 1.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.1 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 2.1 GO:0003407 neural retina development(GO:0003407)
0.0 1.2 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.9 GO:0023014 signal transduction by protein phosphorylation(GO:0023014)
0.0 1.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.0 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.9 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 2.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 2.2 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.5 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 2.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 1.1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.2 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 2.7 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.5 GO:0007264 small GTPase mediated signal transduction(GO:0007264)
0.0 0.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.8 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 1.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0042116 macrophage activation(GO:0042116)
0.0 1.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.9 GO:0050871 positive regulation of B cell activation(GO:0050871)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.4 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.3 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.3 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.3 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 3.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.9 GO:0033269 internode region of axon(GO:0033269)
0.7 9.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.7 2.8 GO:0042585 germinal vesicle(GO:0042585)
0.3 0.9 GO:0008623 CHRAC(GO:0008623)
0.3 1.7 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.3 2.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 2.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 1.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.8 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 2.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.0 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:1990015 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.1 4.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 3.0 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 3.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 4.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.3 GO:0000322 storage vacuole(GO:0000322)
0.1 2.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.4 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 2.3 GO:0071565 nBAF complex(GO:0071565)
0.1 2.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.6 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 4.2 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 8.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 5.6 GO:0005871 kinesin complex(GO:0005871)
0.1 1.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 1.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 4.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 1.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.7 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.2 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 1.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 5.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 4.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.9 GO:0099738 cell cortex region(GO:0099738)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 5.2 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.6 6.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.5 10.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.5 2.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.5 1.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.4 1.7 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.4 8.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.4 1.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.4 1.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 1.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.3 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 3.5 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 2.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 0.6 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.2 1.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 0.6 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 3.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 2.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 0.6 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.1 8.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.6 GO:0008142 oxysterol binding(GO:0008142)
0.1 6.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.1 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.1 1.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 2.1 GO:0000150 recombinase activity(GO:0000150)
0.1 2.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.6 GO:0005119 smoothened binding(GO:0005119)
0.1 1.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.9 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0043398 HLH domain binding(GO:0043398)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 2.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 5.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.8 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 1.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 0.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 1.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.3 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.9 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.1 2.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 3.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 4.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.5 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 5.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0031996 thioesterase binding(GO:0031996)
0.0 3.4 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 5.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 6.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 5.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 1.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.7 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 4.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.4 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 1.5 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 1.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 2.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 4.4 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 4.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 7.3 GO:0005525 GTP binding(GO:0005525)
0.0 1.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 1.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 6.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 9.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.1 4.6 PID ATR PATHWAY ATR signaling pathway
0.1 6.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 4.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 2.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 5.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 3.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.3 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 6.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 21.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 5.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 2.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 4.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 4.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 6.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.1 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.9 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes